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Network neighborhood for query Sequence : P73L_MOUSE

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P73L_MOUSE
SwissProt Accessions	O88898, O88897, O88899, O89097, Q8C826, Q9QWY9, Q9QWZ0	Gene names	Tp73l, P63, P73l, Trp63
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Transformation-related protein 63).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

P73L_HUMAN
θ value	0 (rank : 1)	NC score	0.997089 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

P73L_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	O88898, O88897, O88899, O89097, Q8C826, Q9QWY9, Q9QWZ0	Gene names	Tp73l, P63, P73l, Trp63
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Transformation-related protein 63).

P73_HUMAN
θ value	0 (rank : 3)	NC score	0.964130 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).

P53_HUMAN
θ value	4.67263e-73 (rank : 4)	NC score	0.907222 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

P53_MOUSE
θ value	6.7473e-72 (rank : 5)	NC score	0.911548 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P02340, Q9QUP3	Gene names	Tp53, P53, Trp53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53).

TULP4_HUMAN
θ value	0.0193708 (rank : 6)	NC score	0.085307 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	426	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

FOXI1_MOUSE
θ value	0.0252991 (rank : 7)	NC score	0.034817 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q922I5, Q5SRI5, Q9D299	Gene names	Foxi1
Domain Architecture	No domain graphic available
Description	Forkhead box protein I1.

EVI2B_MOUSE
θ value	0.0961366 (rank : 8)	NC score	0.118730 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

HELZ_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.056147 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

MLL2_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.047570 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	1788	Shared Neighborhood Hits	42
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SAMD4_HUMAN
θ value	0.163984 (rank : 11)	NC score	0.072422 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

ABI3_HUMAN
θ value	0.365318 (rank : 12)	NC score	0.051127 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

RBM12_MOUSE
θ value	0.365318 (rank : 13)	NC score	0.043775 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	313	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

CRX_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.021158 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	359	Shared Neighborhood Hits	8
SwissProt Accessions	O54751	Gene names	Crx
Domain Architecture
Description	Cone-rod homeobox protein.

DYR1B_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.010222 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	799	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

WBS14_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.050221 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	171	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

BRWD2_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.063835 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZH6, Q5VWA1	Gene names	BRWD2, WDR11
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 2 (WD repeat protein 11).

EPHA4_MOUSE
θ value	0.813845 (rank : 18)	NC score	0.006846 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	982	Shared Neighborhood Hits	7
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

FHOD1_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.050492 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	217	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

MLL3_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.045708 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	1644	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CBP_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.039167 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	941	Shared Neighborhood Hits	37
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SYNP2_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.034301 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	252	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

OXSR1_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.005149 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	874	Shared Neighborhood Hits	9
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

WASF2_MOUSE
θ value	1.38821 (rank : 24)	NC score	0.035225 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	315	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

ZN313_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.025935 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

CPSF6_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.046592 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	359	Shared Neighborhood Hits	16
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.046796 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	356	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

DIAP1_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.034233 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	784	Shared Neighborhood Hits	20
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DYM_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.048429 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHY3	Gene names	Dym
Domain Architecture	No domain graphic available
Description	Dymeclin.

PCLO_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.028065 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	2275	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RSMB_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.045130 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	P27048, Q3UJT1	Gene names	Snrpb
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB).

DIAP3_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.033957 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	209	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

MAST1_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.005450 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	1146	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ATN1_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.037621 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	676	Shared Neighborhood Hits	26
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

K0773_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.032341 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q86XD5, Q7L0D6, Q86T97	Gene names	KIAA0773
Domain Architecture	No domain graphic available
Description	Uncharacterized protein KIAA0773.

MAGE1_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.023946 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	1389	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PCLO_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.025948 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	2046	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RBM16_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.043750 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	300	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

RSMB_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.039521 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

TULP4_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.053108 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	247	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

3BP1_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.016469 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CBP_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.035163 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	1051	Shared Neighborhood Hits	43
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DIAP1_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.031497 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	839	Shared Neighborhood Hits	21
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

DYM_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.040907 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q7RTS9, Q6P2P5, Q8N2M0, Q9BVE9	Gene names	DYM
Domain Architecture	No domain graphic available
Description	Dymeclin (Dyggve-Melchior-Clausen syndrome protein).

GGN_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.031872 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	269	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MAML2_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.041389 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	360	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MLL4_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.029579 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	722	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NPL4_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.043547 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

NPL4_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.043664 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P60670	Gene names	Nploc4, Kiaa1499, Npl4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

RERE_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.027905 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	785	Shared Neighborhood Hits	31
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RIN3_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.022416 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	239	Shared Neighborhood Hits	14
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SHC3_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.016187 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

SMAD5_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.016561 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	Q99717, O14688, Q15798, Q9UQA1	Gene names	SMAD5, MADH5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (hSmad5) (JV5-1).

SOCS7_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.023442 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

YLPM1_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.028767 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

ABI2_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.023454 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

CRX_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.012746 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	360	Shared Neighborhood Hits	6
SwissProt Accessions	O43186	Gene names	CRX, CORD2
Domain Architecture
Description	Cone-rod homeobox protein.

DDEF2_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.011113 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	625	Shared Neighborhood Hits	14
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

ENAH_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.026705 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	919	Shared Neighborhood Hits	25
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EPHA4_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.004294 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	975	Shared Neighborhood Hits	7
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

MUC7_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.026440 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	538	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PRDM4_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.000428 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	749	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKN5, Q9UFA6	Gene names	PRDM4, PFM1
Domain Architecture
Description	PR domain zinc finger protein 4 (PR domain-containing protein 4).

PTC1_MOUSE
θ value	5.27518 (rank : 63)	NC score	0.015825 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q61115	Gene names	Ptch1, Ptch
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

RBM12_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.034989 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	298	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SF01_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.029124 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	287	Shared Neighborhood Hits	15
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SRRM2_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.025235 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	1296	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.024956 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	1470	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ZIC5_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.001973 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	774	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

ABI2_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.023819 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	350	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

CAP1_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.016696 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q01518, Q53HR7, Q5T0S1, Q6I9U6	Gene names	CAP1, CAP
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

CASP9_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.014806 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	P55211, O95348, Q92852, Q9BQ62, Q9UEQ3, Q9UIJ8	Gene names	CASP9, MCH6
Domain Architecture
Description	Caspase-9 precursor (EC 3.4.22.-) (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6) (Apoptotic protease Mch-6) (Apoptotic protease- activating factor 3) (APAF-3) [Contains: Caspase-9 subunit p35; Caspase-9 subunit p10].

ENAH_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.021730 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	784	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

EVL_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.017251 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	203	Shared Neighborhood Hits	11
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FMN2_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.029997 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	484	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

PI5PA_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.023524 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	749	Shared Neighborhood Hits	38
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ZN295_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.002769 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	847	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

AFF1_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.013511 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	506	Shared Neighborhood Hits	13
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CCNK_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.023156 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	350	Shared Neighborhood Hits	14
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

DIAP3_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.028992 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	221	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

F113A_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.018737 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1Z5	Gene names	Fam113a
Domain Architecture	No domain graphic available
Description	Protein FAM113A.

ITSN2_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.005243 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	1371	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MLL3_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.034381 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	1399	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RED1_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.007002 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P78563, O00395, O00465, O00691, O00692, P78555, Q8NFD1	Gene names	ADARB1, ADAR2, DRADA2, RED1
Domain Architecture
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

SETBP_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.019996 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	305	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETBP_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.021158 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	352	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SH2D3_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.011017 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

SMAD1_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.015552 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

SMP1L_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.007353 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

Hits sorted by NC score

P73L_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	O88898, O88897, O88899, O89097, Q8C826, Q9QWY9, Q9QWZ0	Gene names	Tp73l, P63, P73l, Trp63
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Transformation-related protein 63).

P73L_HUMAN
NC score	0.997089 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	102	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

P73_HUMAN
NC score	0.964130 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).

P53_MOUSE
NC score	0.911548 (rank : 4)	θ value	6.7473e-72 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P02340, Q9QUP3	Gene names	Tp53, P53, Trp53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53).

P53_HUMAN
NC score	0.907222 (rank : 5)	θ value	4.67263e-73 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

EVI2B_MOUSE
NC score	0.118730 (rank : 6)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

TULP4_HUMAN
NC score	0.085307 (rank : 7)	θ value	0.0193708 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	426	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

SAMD4_HUMAN
NC score	0.072422 (rank : 8)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

BRWD2_HUMAN
NC score	0.063835 (rank : 9)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	94	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZH6, Q5VWA1	Gene names	BRWD2, WDR11
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 2 (WD repeat protein 11).

HELZ_HUMAN
NC score	0.056147 (rank : 10)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

TULP4_MOUSE
NC score	0.053108 (rank : 11)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	247	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JIL5, Q8CA75, Q922C2	Gene names	Tulp4, Tusp
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ABI3_HUMAN
NC score	0.051127 (rank : 12)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P2A4, Q9H0P6	Gene names	ABI3, NESH
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

FHOD1_MOUSE
NC score	0.050492 (rank : 13)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	217	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

WBS14_MOUSE
NC score	0.050221 (rank : 14)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	171	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

DYM_MOUSE
NC score	0.048429 (rank : 15)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHY3	Gene names	Dym
Domain Architecture	No domain graphic available
Description	Dymeclin.

MLL2_HUMAN
NC score	0.047570 (rank : 16)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	1788	Shared Neighborhood Hits	42
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CPSF6_MOUSE
NC score	0.046796 (rank : 17)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	356	Shared Neighborhood Hits	16
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CPSF6_HUMAN
NC score	0.046592 (rank : 18)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	359	Shared Neighborhood Hits	16
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

MLL3_HUMAN
NC score	0.045708 (rank : 19)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	1644	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RSMB_MOUSE
NC score	0.045130 (rank : 20)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	7
SwissProt Accessions	P27048, Q3UJT1	Gene names	Snrpb
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB).

RBM12_MOUSE
NC score	0.043775 (rank : 21)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	313	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM16_HUMAN
NC score	0.043750 (rank : 22)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	300	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

NPL4_MOUSE
NC score	0.043664 (rank : 23)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P60670	Gene names	Nploc4, Kiaa1499, Npl4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

NPL4_HUMAN
NC score	0.043547 (rank : 24)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

MAML2_HUMAN
NC score	0.041389 (rank : 25)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	360	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

DYM_HUMAN
NC score	0.040907 (rank : 26)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q7RTS9, Q6P2P5, Q8N2M0, Q9BVE9	Gene names	DYM
Domain Architecture	No domain graphic available
Description	Dymeclin (Dyggve-Melchior-Clausen syndrome protein).

RSMB_HUMAN
NC score	0.039521 (rank : 27)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

CBP_HUMAN
NC score	0.039167 (rank : 28)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	941	Shared Neighborhood Hits	37
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

ATN1_HUMAN
NC score	0.037621 (rank : 29)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	676	Shared Neighborhood Hits	26
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

WASF2_MOUSE
NC score	0.035225 (rank : 30)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	315	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BH43	Gene names	Wasf2, Wave2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2).

CBP_MOUSE
NC score	0.035163 (rank : 31)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	1051	Shared Neighborhood Hits	43
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

RBM12_HUMAN
NC score	0.034989 (rank : 32)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	298	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

FOXI1_MOUSE
NC score	0.034817 (rank : 33)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q922I5, Q5SRI5, Q9D299	Gene names	Foxi1
Domain Architecture	No domain graphic available
Description	Forkhead box protein I1.

MLL3_MOUSE
NC score	0.034381 (rank : 34)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	1399	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SYNP2_MOUSE
NC score	0.034301 (rank : 35)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	252	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

DIAP1_HUMAN
NC score	0.034233 (rank : 36)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	784	Shared Neighborhood Hits	20
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP3_HUMAN
NC score	0.033957 (rank : 37)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	209	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

K0773_HUMAN
NC score	0.032341 (rank : 38)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q86XD5, Q7L0D6, Q86T97	Gene names	KIAA0773
Domain Architecture	No domain graphic available
Description	Uncharacterized protein KIAA0773.

GGN_HUMAN
NC score	0.031872 (rank : 39)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	269	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

DIAP1_MOUSE
NC score	0.031497 (rank : 40)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	839	Shared Neighborhood Hits	21
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

FMN2_HUMAN
NC score	0.029997 (rank : 41)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	484	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MLL4_HUMAN
NC score	0.029579 (rank : 42)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	722	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SF01_HUMAN
NC score	0.029124 (rank : 43)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	287	Shared Neighborhood Hits	15
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

DIAP3_MOUSE
NC score	0.028992 (rank : 44)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	221	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

YLPM1_MOUSE
NC score	0.028767 (rank : 45)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	505	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

PCLO_MOUSE
NC score	0.028065 (rank : 46)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	2275	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RERE_MOUSE
NC score	0.027905 (rank : 47)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	785	Shared Neighborhood Hits	31
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

ENAH_MOUSE
NC score	0.026705 (rank : 48)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	919	Shared Neighborhood Hits	25
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

MUC7_HUMAN
NC score	0.026440 (rank : 49)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	538	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PCLO_HUMAN
NC score	0.025948 (rank : 50)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	2046	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ZN313_MOUSE
NC score	0.025935 (rank : 51)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	273	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

SRRM2_HUMAN
NC score	0.025235 (rank : 52)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	1296	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
NC score	0.024956 (rank : 53)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	1470	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MAGE1_HUMAN
NC score	0.023946 (rank : 54)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	1389	Shared Neighborhood Hits	51
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ABI2_HUMAN
NC score	0.023819 (rank : 55)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	350	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

PI5PA_HUMAN
NC score	0.023524 (rank : 56)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	749	Shared Neighborhood Hits	38
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ABI2_MOUSE
NC score	0.023454 (rank : 57)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	266	Shared Neighborhood Hits	10
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

SOCS7_MOUSE
NC score	0.023442 (rank : 58)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHQ2	Gene names	Socs7, Cish7, Nap4
Domain Architecture
Description	Suppressor of cytokine signaling 7 (SOCS-7).

CCNK_MOUSE
NC score	0.023156 (rank : 59)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	350	Shared Neighborhood Hits	14
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

RIN3_MOUSE
NC score	0.022416 (rank : 60)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	239	Shared Neighborhood Hits	14
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ENAH_HUMAN
NC score	0.021730 (rank : 61)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	784	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

CRX_MOUSE
NC score	0.021158 (rank : 62)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	359	Shared Neighborhood Hits	8
SwissProt Accessions	O54751	Gene names	Crx
Domain Architecture
Description	Cone-rod homeobox protein.

SETBP_MOUSE
NC score	0.021158 (rank : 63)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	352	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETBP_HUMAN
NC score	0.019996 (rank : 64)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	305	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

F113A_MOUSE
NC score	0.018737 (rank : 65)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P1Z5	Gene names	Fam113a
Domain Architecture	No domain graphic available
Description	Protein FAM113A.

EVL_MOUSE
NC score	0.017251 (rank : 66)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	203	Shared Neighborhood Hits	11
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

CAP1_HUMAN
NC score	0.016696 (rank : 67)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q01518, Q53HR7, Q5T0S1, Q6I9U6	Gene names	CAP1, CAP
Domain Architecture
Description	Adenylyl cyclase-associated protein 1 (CAP 1).

SMAD5_HUMAN
NC score	0.016561 (rank : 68)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	57	Shared Neighborhood Hits	7
SwissProt Accessions	Q99717, O14688, Q15798, Q9UQA1	Gene names	SMAD5, MADH5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (hSmad5) (JV5-1).

3BP1_MOUSE
NC score	0.016469 (rank : 69)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	238	Shared Neighborhood Hits	9
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

SHC3_HUMAN
NC score	0.016187 (rank : 70)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	Q92529, Q8TAP2, Q9UCX5	Gene names	SHC3, NSHC, SHCC
Domain Architecture
Description	SHC-transforming protein 3 (SH2 domain protein C3) (Src homology 2 domain-containing-transforming protein C3) (Neuronal Shc) (N-Shc) (Protein Rai).

PTC1_MOUSE
NC score	0.015825 (rank : 71)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q61115	Gene names	Ptch1, Ptch
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

SMAD1_HUMAN
NC score	0.015552 (rank : 72)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

CASP9_HUMAN
NC score	0.014806 (rank : 73)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	P55211, O95348, Q92852, Q9BQ62, Q9UEQ3, Q9UIJ8	Gene names	CASP9, MCH6
Domain Architecture
Description	Caspase-9 precursor (EC 3.4.22.-) (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6) (Apoptotic protease Mch-6) (Apoptotic protease- activating factor 3) (APAF-3) [Contains: Caspase-9 subunit p35; Caspase-9 subunit p10].

AFF1_HUMAN
NC score	0.013511 (rank : 74)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	506	Shared Neighborhood Hits	13
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CRX_HUMAN
NC score	0.012746 (rank : 75)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	360	Shared Neighborhood Hits	6
SwissProt Accessions	O43186	Gene names	CRX, CORD2
Domain Architecture
Description	Cone-rod homeobox protein.

DDEF2_MOUSE
NC score	0.011113 (rank : 76)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	625	Shared Neighborhood Hits	14
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

SH2D3_MOUSE
NC score	0.011017 (rank : 77)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZS8, Q9JME1	Gene names	Sh2d3c, Chat, Shep1
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (SH2 domain-containing Eph receptor- binding protein 1) (Cas/HEF1-associated signal transducer).

DYR1B_MOUSE
NC score	0.010222 (rank : 78)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	799	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z188	Gene names	Dyrk1b
Domain Architecture
Description	Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1).

SMP1L_MOUSE
NC score	0.007353 (rank : 79)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

RED1_HUMAN
NC score	0.007002 (rank : 80)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P78563, O00395, O00465, O00691, O00692, P78555, Q8NFD1	Gene names	ADARB1, ADAR2, DRADA2, RED1
Domain Architecture
Description	Double-stranded RNA-specific editase 1 (EC 3.5.-.-) (dsRNA adenosine deaminase) (RNA-editing deaminase 1) (RNA-editing enzyme 1).

EPHA4_MOUSE
NC score	0.006846 (rank : 81)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	982	Shared Neighborhood Hits	7
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

MAST1_HUMAN
NC score	0.005450 (rank : 82)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	1146	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ITSN2_MOUSE
NC score	0.005243 (rank : 83)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	1371	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

OXSR1_HUMAN
NC score	0.005149 (rank : 84)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	874	Shared Neighborhood Hits	9
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

EPHA4_HUMAN
NC score	0.004294 (rank : 85)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	975	Shared Neighborhood Hits	7
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

ZN295_HUMAN
NC score	0.002769 (rank : 86)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	847	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULJ3, Q6P4R0	Gene names	ZNF295, KIAA1227, ZBTB21
Domain Architecture
Description	Zinc finger protein 295 (Zinc finger and BTB domain-containing protein 21).

ZIC5_HUMAN
NC score	0.001973 (rank : 87)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	774	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

PRDM4_HUMAN
NC score	0.000428 (rank : 88)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	749	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKN5, Q9UFA6	Gene names	PRDM4, PFM1
Domain Architecture
Description	PR domain zinc finger protein 4 (PR domain-containing protein 4).