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Network neighborhood for query Sequence : P73_HUMAN

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P73_HUMAN
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

P73L_HUMAN
θ value	0 (rank : 1)	NC score	0.962297 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

P73L_MOUSE
θ value	0 (rank : 2)	NC score	0.964130 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	88	Shared Neighborhood Hits	11
SwissProt Accessions	O88898, O88897, O88899, O89097, Q8C826, Q9QWY9, Q9QWZ0	Gene names	Tp73l, P63, P73l, Trp63
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Transformation-related protein 63).

P73_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).

P53_HUMAN
θ value	3.95564e-72 (rank : 4)	NC score	0.919054 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

P53_MOUSE
θ value	1.96316e-71 (rank : 5)	NC score	0.923116 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P02340, Q9QUP3	Gene names	Tp53, P53, Trp53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53).

MNT_HUMAN
θ value	0.00869519 (rank : 6)	NC score	0.063055 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	496	Shared Neighborhood Hits	11
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

EVI2B_MOUSE
θ value	0.0431538 (rank : 7)	NC score	0.123639 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

GCFC_HUMAN
θ value	0.21417 (rank : 8)	NC score	0.052127 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5B6, Q9NYQ0	Gene names	GCFC, C21orf66
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor homolog.

PYRG1_MOUSE
θ value	0.279714 (rank : 9)	NC score	0.044906 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P70698, Q922Y4	Gene names	Ctps
Domain Architecture
Description	CTP synthase 1 (EC 6.3.4.2) (UTP--ammonia ligase 1) (CTP synthetase 1).

DOK2_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.032765 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

PO2F3_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.015831 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	328	Shared Neighborhood Hits	2
SwissProt Accessions	P31362	Gene names	Pou2f3, Epoc1, Oct11, Otf-11, Otf11
Domain Architecture
Description	POU domain, class 2, transcription factor 3 (Octamer-binding transcription factor 11) (Oct-11) (Epoc-1).

TARA_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.026783 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	1133	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NEMO_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.016646 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	820	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

TCF20_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.033622 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	323	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

WIRE_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.044725 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	310	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CELR3_MOUSE
θ value	1.06291 (rank : 16)	NC score	0.006787 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	687	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

MAML2_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.048564 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	360	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

PPRB_MOUSE
θ value	1.06291 (rank : 18)	NC score	0.027762 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	354	Shared Neighborhood Hits	12
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

PYRG1_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.040335 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P17812, Q5VW67, Q96GK6	Gene names	CTPS
Domain Architecture
Description	CTP synthase 1 (EC 6.3.4.2) (UTP--ammonia ligase 1) (CTP synthetase 1).

CDK4_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.003461 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	834	Shared Neighborhood Hits	5
SwissProt Accessions	P11802, O00576	Gene names	CDK4
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3).

MTF1_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.001747 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	814	Shared Neighborhood Hits	7
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

DUS8_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.013734 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

CCNK_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.023688 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	350	Shared Neighborhood Hits	12
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

FOXK2_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.009547 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

K1802_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.022453 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	1596	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1849_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.015106 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

NEST_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.008509 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	1305	Shared Neighborhood Hits	8
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PGBM_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.005584 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	1113	Shared Neighborhood Hits	9
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TAU_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.019052 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	502	Shared Neighborhood Hits	18
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

WASF3_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.019528 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	204	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

WIRE_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.037511 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

ENAM_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.028175 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	229	Shared Neighborhood Hits	13
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

LPP_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.017803 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	775	Shared Neighborhood Hits	24
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

RCOR3_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.021677 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

RPB1_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.027656 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	362	Shared Neighborhood Hits	14
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.027535 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	363	Shared Neighborhood Hits	14
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

T22D2_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.020884 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	250	Shared Neighborhood Hits	7
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

ARI1A_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.016958 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	787	Shared Neighborhood Hits	16
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CEBPB_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.015966 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	P28033	Gene names	Cebpb
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Interleukin-6- dependent-binding protein) (IL-6DBP) (Liver-enriched transcriptional activator) (LAP) (AGP/EBP).

HRX_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.013812 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	825	Shared Neighborhood Hits	12
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

K0999_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.001004 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	931	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

MANS1_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.022932 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H8J5, Q8NEC1	Gene names	MANSC1
Domain Architecture	No domain graphic available
Description	MANSC domain-containing protein 1 precursor.

RCOR3_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.021748 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

SMAD1_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.017938 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

ATF6A_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.015925 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

CD248_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.014907 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	679	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CDK4_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.002240 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	838	Shared Neighborhood Hits	5
SwissProt Accessions	P30285	Gene names	Cdk4, Crk3
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3) (CRK3).

MNT_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.040864 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	432	Shared Neighborhood Hits	10
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NPL4_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.041458 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

NPL4_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.041572 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P60670	Gene names	Nploc4, Kiaa1499, Npl4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

PCDH9_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.004648 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

SGIP1_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.018460 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SMAD1_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.012337 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

TRPM7_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.008586 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TTBK2_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.004920 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	811	Shared Neighborhood Hits	8
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

ARS2_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.012283 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	212	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

DYH5_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.007997 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

EP400_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.008234 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	556	Shared Neighborhood Hits	13
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

KLHL1_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.002868 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	193	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI74	Gene names	Klhl1
Domain Architecture
Description	Kelch-like protein 1.

NCOR2_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.013385 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	790	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PHC3_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.010893 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

TRI66_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.008472 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	479	Shared Neighborhood Hits	10
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

K1802_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.015526 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	1378	Shared Neighborhood Hits	26
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MKL2_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.008589 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

MUC2_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.013637 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	906	Shared Neighborhood Hits	20
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.010724 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	1020	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PME17_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.010815 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q60696	Gene names	Silv, D10H12S53E, Pmel17, Si
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Silver locus protein).

RAI1_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.017792 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	360	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TREF1_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.010407 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	651	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

TSH2_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.005731 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	467	Shared Neighborhood Hits	3
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

ZIMP7_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.010257 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	566	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

Hits sorted by NC score

P73_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).

P73L_MOUSE
NC score	0.964130 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	88	Shared Neighborhood Hits	11
SwissProt Accessions	O88898, O88897, O88899, O89097, Q8C826, Q9QWY9, Q9QWZ0	Gene names	Tp73l, P63, P73l, Trp63
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Transformation-related protein 63).

P73L_HUMAN
NC score	0.962297 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

P53_MOUSE
NC score	0.923116 (rank : 4)	θ value	1.96316e-71 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P02340, Q9QUP3	Gene names	Tp53, P53, Trp53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53).

P53_HUMAN
NC score	0.919054 (rank : 5)	θ value	3.95564e-72 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	P04637, Q15086, Q15087, Q15088, Q16535, Q16807, Q16808, Q16809, Q16810, Q16811, Q16848, Q86UG1, Q8J016, Q99659, Q9BTM4, Q9HAQ8, Q9NP68, Q9NPJ2, Q9NZD0, Q9UBI2, Q9UQ61	Gene names	TP53, P53
Domain Architecture
Description	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13).

EVI2B_MOUSE
NC score	0.123639 (rank : 6)	θ value	0.0431538 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VD58, Q3U1A3	Gene names	Evi2b
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

MNT_HUMAN
NC score	0.063055 (rank : 7)	θ value	0.00869519 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	496	Shared Neighborhood Hits	11
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

GCFC_HUMAN
NC score	0.052127 (rank : 8)	θ value	0.21417 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5B6, Q9NYQ0	Gene names	GCFC, C21orf66
Domain Architecture	No domain graphic available
Description	GC-rich sequence DNA-binding factor homolog.

MAML2_HUMAN
NC score	0.048564 (rank : 9)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	360	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

PYRG1_MOUSE
NC score	0.044906 (rank : 10)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P70698, Q922Y4	Gene names	Ctps
Domain Architecture
Description	CTP synthase 1 (EC 6.3.4.2) (UTP--ammonia ligase 1) (CTP synthetase 1).

WIRE_MOUSE
NC score	0.044725 (rank : 11)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	310	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

NPL4_MOUSE
NC score	0.041572 (rank : 12)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	16	Shared Neighborhood Hits	5
SwissProt Accessions	P60670	Gene names	Nploc4, Kiaa1499, Npl4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

NPL4_HUMAN
NC score	0.041458 (rank : 13)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

MNT_MOUSE
NC score	0.040864 (rank : 14)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	432	Shared Neighborhood Hits	10
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PYRG1_HUMAN
NC score	0.040335 (rank : 15)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P17812, Q5VW67, Q96GK6	Gene names	CTPS
Domain Architecture
Description	CTP synthase 1 (EC 6.3.4.2) (UTP--ammonia ligase 1) (CTP synthetase 1).

WIRE_HUMAN
NC score	0.037511 (rank : 16)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

TCF20_HUMAN
NC score	0.033622 (rank : 17)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	323	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

DOK2_HUMAN
NC score	0.032765 (rank : 18)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

ENAM_MOUSE
NC score	0.028175 (rank : 19)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	229	Shared Neighborhood Hits	13
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

PPRB_MOUSE
NC score	0.027762 (rank : 20)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	354	Shared Neighborhood Hits	12
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RPB1_HUMAN
NC score	0.027656 (rank : 21)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	362	Shared Neighborhood Hits	14
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
NC score	0.027535 (rank : 22)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	363	Shared Neighborhood Hits	14
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

TARA_MOUSE
NC score	0.026783 (rank : 23)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	1133	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CCNK_MOUSE
NC score	0.023688 (rank : 24)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	350	Shared Neighborhood Hits	12
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

MANS1_HUMAN
NC score	0.022932 (rank : 25)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H8J5, Q8NEC1	Gene names	MANSC1
Domain Architecture	No domain graphic available
Description	MANSC domain-containing protein 1 precursor.

K1802_MOUSE
NC score	0.022453 (rank : 26)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	1596	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RCOR3_MOUSE
NC score	0.021748 (rank : 27)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

RCOR3_HUMAN
NC score	0.021677 (rank : 28)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

T22D2_HUMAN
NC score	0.020884 (rank : 29)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	250	Shared Neighborhood Hits	7
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

WASF3_HUMAN
NC score	0.019528 (rank : 30)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	204	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UPY6, O94974	Gene names	WASF3, KIAA0900, SCAR3, WAVE3
Domain Architecture
Description	Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3).

TAU_MOUSE
NC score	0.019052 (rank : 31)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	502	Shared Neighborhood Hits	18
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

SGIP1_MOUSE
NC score	0.018460 (rank : 32)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SMAD1_HUMAN
NC score	0.017938 (rank : 33)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

LPP_HUMAN
NC score	0.017803 (rank : 34)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	775	Shared Neighborhood Hits	24
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

RAI1_HUMAN
NC score	0.017792 (rank : 35)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	360	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ARI1A_HUMAN
NC score	0.016958 (rank : 36)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	787	Shared Neighborhood Hits	16
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

NEMO_HUMAN
NC score	0.016646 (rank : 37)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	820	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

CEBPB_MOUSE
NC score	0.015966 (rank : 38)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	101	Shared Neighborhood Hits	2
SwissProt Accessions	P28033	Gene names	Cebpb
Domain Architecture
Description	CCAAT/enhancer-binding protein beta (C/EBP beta) (Interleukin-6- dependent-binding protein) (IL-6DBP) (Liver-enriched transcriptional activator) (LAP) (AGP/EBP).

ATF6A_HUMAN
NC score	0.015925 (rank : 39)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

PO2F3_MOUSE
NC score	0.015831 (rank : 40)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	328	Shared Neighborhood Hits	2
SwissProt Accessions	P31362	Gene names	Pou2f3, Epoc1, Oct11, Otf-11, Otf11
Domain Architecture
Description	POU domain, class 2, transcription factor 3 (Octamer-binding transcription factor 11) (Oct-11) (Epoc-1).

K1802_HUMAN
NC score	0.015526 (rank : 41)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	1378	Shared Neighborhood Hits	26
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

K1849_HUMAN
NC score	0.015106 (rank : 42)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

CD248_HUMAN
NC score	0.014907 (rank : 43)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	679	Shared Neighborhood Hits	30
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

HRX_HUMAN
NC score	0.013812 (rank : 44)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	825	Shared Neighborhood Hits	12
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

DUS8_MOUSE
NC score	0.013734 (rank : 45)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

MUC2_HUMAN
NC score	0.013637 (rank : 46)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	906	Shared Neighborhood Hits	20
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NCOR2_MOUSE
NC score	0.013385 (rank : 47)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	790	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

SMAD1_MOUSE
NC score	0.012337 (rank : 48)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

ARS2_MOUSE
NC score	0.012283 (rank : 49)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	212	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MR6, Q99MR4, Q99MR5, Q99MR7	Gene names	Ars2, Asr2
Domain Architecture
Description	Arsenite-resistance protein 2.

PHC3_MOUSE
NC score	0.010893 (rank : 50)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

PME17_MOUSE
NC score	0.010815 (rank : 51)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q60696	Gene names	Silv, D10H12S53E, Pmel17, Si
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Silver locus protein).

MUC5B_HUMAN
NC score	0.010724 (rank : 52)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	1020	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TREF1_HUMAN
NC score	0.010407 (rank : 53)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	651	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

ZIMP7_MOUSE
NC score	0.010257 (rank : 54)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	566	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

FOXK2_HUMAN
NC score	0.009547 (rank : 55)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

MKL2_MOUSE
NC score	0.008589 (rank : 56)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

TRPM7_HUMAN
NC score	0.008586 (rank : 57)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	104	Shared Neighborhood Hits	2
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

NEST_HUMAN
NC score	0.008509 (rank : 58)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	1305	Shared Neighborhood Hits	8
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

TRI66_HUMAN
NC score	0.008472 (rank : 59)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	479	Shared Neighborhood Hits	10
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

EP400_HUMAN
NC score	0.008234 (rank : 60)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	556	Shared Neighborhood Hits	13
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

DYH5_HUMAN
NC score	0.007997 (rank : 61)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	323	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

CELR3_MOUSE
NC score	0.006787 (rank : 62)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	687	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

TSH2_MOUSE
NC score	0.005731 (rank : 63)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	467	Shared Neighborhood Hits	3
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

PGBM_HUMAN
NC score	0.005584 (rank : 64)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	1113	Shared Neighborhood Hits	9
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TTBK2_MOUSE
NC score	0.004920 (rank : 65)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	811	Shared Neighborhood Hits	8
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

PCDH9_HUMAN
NC score	0.004648 (rank : 66)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC56	Gene names	PCDH9
Domain Architecture
Description	Protocadherin-9 precursor.

CDK4_HUMAN
NC score	0.003461 (rank : 67)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	834	Shared Neighborhood Hits	5
SwissProt Accessions	P11802, O00576	Gene names	CDK4
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3).

KLHL1_MOUSE
NC score	0.002868 (rank : 68)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	193	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JI74	Gene names	Klhl1
Domain Architecture
Description	Kelch-like protein 1.

CDK4_MOUSE
NC score	0.002240 (rank : 69)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	838	Shared Neighborhood Hits	5
SwissProt Accessions	P30285	Gene names	Cdk4, Crk3
Domain Architecture
Description	Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3) (CRK3).

MTF1_HUMAN
NC score	0.001747 (rank : 70)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	814	Shared Neighborhood Hits	7
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

K0999_MOUSE
NC score	0.001004 (rank : 71)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	931	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).