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Network neighborhood for query Sequence : SMAD1_MOUSE

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SMAD1_MOUSE
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMAD1_HUMAN
θ value	0 (rank : 1)	NC score	0.999236 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	59	Shared Neighborhood Hits	46
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

SMAD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

SMAD5_HUMAN
θ value	0 (rank : 3)	NC score	0.995033 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	Q99717, O14688, Q15798, Q9UQA1	Gene names	SMAD5, MADH5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (hSmad5) (JV5-1).

SMAD5_MOUSE
θ value	0 (rank : 4)	NC score	0.993891 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

SMAD9_HUMAN
θ value	0 (rank : 5)	NC score	0.992606 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	O15198, O14989	Gene names	SMAD9, MADH6, MADH9
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Madh6).

SMAD9_MOUSE
θ value	0 (rank : 6)	NC score	0.988540 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JIW5, Q8CFF9	Gene names	Smad9, Madh8, Madh9, Smad8
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Smad8).

SMAD3_HUMAN
θ value	9.54178e-143 (rank : 7)	NC score	0.984424 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	P84022, O09064, O09144, O14510, O35273, Q92940, Q93002, Q9GKR4	Gene names	SMAD3, MADH3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (hMAD-3) (JV15-2) (hSMAD3).

SMAD3_MOUSE
θ value	9.54178e-143 (rank : 8)	NC score	0.984424 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUN5, O09064, O09144, O14510, O35273, Q8BX84, Q92940, Q93002, Q9GKR4	Gene names	Smad3, Madh3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (mMad3).

SMAD2_HUMAN
θ value	8.37844e-131 (rank : 9)	NC score	0.981219 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q15796	Gene names	SMAD2, MADH2, MADR2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (hMAD-2) (JV18-1) (hSMAD2).

SMAD2_MOUSE
θ value	8.37844e-131 (rank : 10)	NC score	0.981221 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q62432, Q9D8P6	Gene names	Smad2, Madh2, Madr2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2).

SMAD4_MOUSE
θ value	1.36269e-64 (rank : 11)	NC score	0.922113 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

SMAD4_HUMAN
θ value	3.96481e-64 (rank : 12)	NC score	0.923628 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q13485	Gene names	SMAD4, DPC4, MADH4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (hSMAD4).

SMAD6_MOUSE
θ value	1.33526e-19 (rank : 13)	NC score	0.768456 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	O35182, Q9CW62	Gene names	Smad6, Madh6, Madh7, Msmad6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (Mad homolog 7).

SMAD6_HUMAN
θ value	8.65492e-19 (rank : 14)	NC score	0.765501 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	O43541, O43654, Q15799, Q9UKZ3	Gene names	SMAD6, MADH6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (hSMAD6).

SMAD7_HUMAN
θ value	1.16975e-15 (rank : 15)	NC score	0.750721 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	O15105, O14740, Q6DK23	Gene names	SMAD7, MADH7, MADH8
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (hSMAD7).

SMAD7_MOUSE
θ value	1.16975e-15 (rank : 16)	NC score	0.751534 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	O35253, O88709	Gene names	Smad7, Madh7
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (Madh8).

IRF4_HUMAN
θ value	0.00020696 (rank : 17)	NC score	0.061264 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

CRSP2_HUMAN
θ value	0.00665767 (rank : 18)	NC score	0.103974 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	380	Shared Neighborhood Hits	16
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

NCOA6_HUMAN
θ value	0.0563607 (rank : 19)	NC score	0.044302 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	1202	Shared Neighborhood Hits	19
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

DAZ1_HUMAN
θ value	0.125558 (rank : 20)	NC score	0.059533 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	192	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQZ3, Q9NQZ4	Gene names	DAZ1, DAZ
Domain Architecture
Description	Deleted in azoospermia protein 1.

DAZ2_HUMAN
θ value	0.125558 (rank : 21)	NC score	0.060072 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q13117, Q96P41, Q9NR91	Gene names	DAZ2
Domain Architecture
Description	Deleted in azoospermia protein 2.

DAZ3_HUMAN
θ value	0.125558 (rank : 22)	NC score	0.060264 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR90	Gene names	DAZ3
Domain Architecture
Description	Deleted in azoospermia protein 3.

DAZ4_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.059602 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	192	Shared Neighborhood Hits	8
SwissProt Accessions	Q86SG3, Q9NR88, Q9NR89	Gene names	DAZ4
Domain Architecture
Description	Deleted in azoospermia protein 4.

NCOA6_MOUSE
θ value	0.125558 (rank : 24)	NC score	0.055460 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	1076	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

COKA1_HUMAN
θ value	0.163984 (rank : 25)	NC score	0.016300 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	403	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CD248_MOUSE
θ value	0.279714 (rank : 26)	NC score	0.018906 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	578	Shared Neighborhood Hits	15
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CSKI1_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.023448 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	1031	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANK2_HUMAN
θ value	0.365318 (rank : 28)	NC score	0.009561 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	1615	Shared Neighborhood Hits	17
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

LPP_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.022463 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	775	Shared Neighborhood Hits	19
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

FAT2_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.009886 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	507	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

SSBP4_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.016673 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	753	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

CEL_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.009252 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	896	Shared Neighborhood Hits	17
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

ZIM10_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.021715 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	577	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

EFS_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.017459 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	348	Shared Neighborhood Hits	8
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

GT2D1_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.024759 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

OGFR_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.011468 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	584	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PO3F4_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.006666 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	P49335, Q5H9G9, Q99410	Gene names	POU3F4, BRN4, OTF9
Domain Architecture
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

CSKI1_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.013365 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	997	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PLCB4_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.003018 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	658	Shared Neighborhood Hits	5
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

GNAS1_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.008416 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	651	Shared Neighborhood Hits	19
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

HXC10_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.002628 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	417	Shared Neighborhood Hits	5
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

LEF1_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.007950 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
θ value	5.27518 (rank : 43)	NC score	0.007788 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

P73_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.012337 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).

BRD8_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.011767 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	422	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CTDP1_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.012041 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	416	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

HXC10_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.002275 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	417	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYD6, O15219, O15220, Q9BVD5	Gene names	HOXC10
Domain Architecture
Description	Homeobox protein Hox-C10.

IRF7_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.025634 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

ITF2_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.005601 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

KBTB4_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.015607 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	187	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NVX7, Q6IA85, Q9BUC3, Q9NV76	Gene names	KBTBD4, BKLHD4
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4).

NCOR2_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.006596 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	870	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

RGS3_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.004820 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	1375	Shared Neighborhood Hits	13
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

WNT16_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.005621 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYS1	Gene names	Wnt16
Domain Architecture
Description	Protein Wnt-16 precursor.

CT2NL_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.001236 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	902	Shared Neighborhood Hits	9
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

HXB13_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.001187 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	377	Shared Neighborhood Hits	4
SwissProt Accessions	Q92826, Q96QM4, Q99810	Gene names	HOXB13
Domain Architecture
Description	Homeobox protein Hox-B13.

MEF2B_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.009937 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	150	Shared Neighborhood Hits	7
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

Hits sorted by NC score

SMAD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

SMAD1_HUMAN
NC score	0.999236 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	59	Shared Neighborhood Hits	46
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

SMAD5_HUMAN
NC score	0.995033 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	Q99717, O14688, Q15798, Q9UQA1	Gene names	SMAD5, MADH5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (hSmad5) (JV5-1).

SMAD5_MOUSE
NC score	0.993891 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	74	Shared Neighborhood Hits	33
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

SMAD9_HUMAN
NC score	0.992606 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	O15198, O14989	Gene names	SMAD9, MADH6, MADH9
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Madh6).

SMAD9_MOUSE
NC score	0.988540 (rank : 6)	θ value	0 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	75	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JIW5, Q8CFF9	Gene names	Smad9, Madh8, Madh9, Smad8
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Smad8).

SMAD3_HUMAN
NC score	0.984424 (rank : 7)	θ value	9.54178e-143 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	P84022, O09064, O09144, O14510, O35273, Q92940, Q93002, Q9GKR4	Gene names	SMAD3, MADH3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (hMAD-3) (JV15-2) (hSMAD3).

SMAD3_MOUSE
NC score	0.984424 (rank : 8)	θ value	9.54178e-143 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUN5, O09064, O09144, O14510, O35273, Q8BX84, Q92940, Q93002, Q9GKR4	Gene names	Smad3, Madh3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (mMad3).

SMAD2_MOUSE
NC score	0.981221 (rank : 9)	θ value	8.37844e-131 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q62432, Q9D8P6	Gene names	Smad2, Madh2, Madr2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2).

SMAD2_HUMAN
NC score	0.981219 (rank : 10)	θ value	8.37844e-131 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q15796	Gene names	SMAD2, MADH2, MADR2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (hMAD-2) (JV18-1) (hSMAD2).

SMAD4_HUMAN
NC score	0.923628 (rank : 11)	θ value	3.96481e-64 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q13485	Gene names	SMAD4, DPC4, MADH4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (hSMAD4).

SMAD4_MOUSE
NC score	0.922113 (rank : 12)	θ value	1.36269e-64 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

SMAD6_MOUSE
NC score	0.768456 (rank : 13)	θ value	1.33526e-19 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	O35182, Q9CW62	Gene names	Smad6, Madh6, Madh7, Msmad6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (Mad homolog 7).

SMAD6_HUMAN
NC score	0.765501 (rank : 14)	θ value	8.65492e-19 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	O43541, O43654, Q15799, Q9UKZ3	Gene names	SMAD6, MADH6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (hSMAD6).

SMAD7_MOUSE
NC score	0.751534 (rank : 15)	θ value	1.16975e-15 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	O35253, O88709	Gene names	Smad7, Madh7
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (Madh8).

SMAD7_HUMAN
NC score	0.750721 (rank : 16)	θ value	1.16975e-15 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	O15105, O14740, Q6DK23	Gene names	SMAD7, MADH7, MADH8
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (hSMAD7).

CRSP2_HUMAN
NC score	0.103974 (rank : 17)	θ value	0.00665767 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	380	Shared Neighborhood Hits	16
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

IRF4_HUMAN
NC score	0.061264 (rank : 18)	θ value	0.00020696 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q15306, Q99660	Gene names	IRF4, MUM1
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (Multiple myeloma oncogene 1).

DAZ3_HUMAN
NC score	0.060264 (rank : 19)	θ value	0.125558 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR90	Gene names	DAZ3
Domain Architecture
Description	Deleted in azoospermia protein 3.

DAZ2_HUMAN
NC score	0.060072 (rank : 20)	θ value	0.125558 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q13117, Q96P41, Q9NR91	Gene names	DAZ2
Domain Architecture
Description	Deleted in azoospermia protein 2.

DAZ4_HUMAN
NC score	0.059602 (rank : 21)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	192	Shared Neighborhood Hits	8
SwissProt Accessions	Q86SG3, Q9NR88, Q9NR89	Gene names	DAZ4
Domain Architecture
Description	Deleted in azoospermia protein 4.

DAZ1_HUMAN
NC score	0.059533 (rank : 22)	θ value	0.125558 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	192	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NQZ3, Q9NQZ4	Gene names	DAZ1, DAZ
Domain Architecture
Description	Deleted in azoospermia protein 1.

NCOA6_MOUSE
NC score	0.055460 (rank : 23)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	1076	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOA6_HUMAN
NC score	0.044302 (rank : 24)	θ value	0.0563607 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	1202	Shared Neighborhood Hits	19
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

IRF7_HUMAN
NC score	0.025634 (rank : 25)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q92985, O00331, O00332, O00333, O75924	Gene names	IRF7
Domain Architecture
Description	Interferon regulatory factor 7 (IRF-7).

GT2D1_MOUSE
NC score	0.024759 (rank : 26)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

CSKI1_MOUSE
NC score	0.023448 (rank : 27)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	1031	Shared Neighborhood Hits	18
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LPP_HUMAN
NC score	0.022463 (rank : 28)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	775	Shared Neighborhood Hits	19
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

ZIM10_HUMAN
NC score	0.021715 (rank : 29)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	577	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

CD248_MOUSE
NC score	0.018906 (rank : 30)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	578	Shared Neighborhood Hits	15
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

EFS_HUMAN
NC score	0.017459 (rank : 31)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	348	Shared Neighborhood Hits	8
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

SSBP4_HUMAN
NC score	0.016673 (rank : 32)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	753	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

COKA1_HUMAN
NC score	0.016300 (rank : 33)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	403	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

KBTB4_HUMAN
NC score	0.015607 (rank : 34)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	187	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NVX7, Q6IA85, Q9BUC3, Q9NV76	Gene names	KBTBD4, BKLHD4
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 4 (BTB and kelch domain-containing protein 4).

CSKI1_HUMAN
NC score	0.013365 (rank : 35)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	997	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

P73_HUMAN
NC score	0.012337 (rank : 36)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).

CTDP1_HUMAN
NC score	0.012041 (rank : 37)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	416	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

BRD8_MOUSE
NC score	0.011767 (rank : 38)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	422	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

OGFR_MOUSE
NC score	0.011468 (rank : 39)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	584	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

MEF2B_HUMAN
NC score	0.009937 (rank : 40)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	150	Shared Neighborhood Hits	7
SwissProt Accessions	Q02080	Gene names	MEF2B, XMEF2
Domain Architecture
Description	Myocyte-specific enhancer factor 2B (Serum response factor-like protein 2) (XMEF2) (RSRFR2).

FAT2_HUMAN
NC score	0.009886 (rank : 41)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	507	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

ANK2_HUMAN
NC score	0.009561 (rank : 42)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	1615	Shared Neighborhood Hits	17
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CEL_HUMAN
NC score	0.009252 (rank : 43)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	896	Shared Neighborhood Hits	17
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

GNAS1_MOUSE
NC score	0.008416 (rank : 44)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	651	Shared Neighborhood Hits	19
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

LEF1_HUMAN
NC score	0.007950 (rank : 45)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
NC score	0.007788 (rank : 46)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

PO3F4_HUMAN
NC score	0.006666 (rank : 47)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	P49335, Q5H9G9, Q99410	Gene names	POU3F4, BRN4, OTF9
Domain Architecture
Description	POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4).

NCOR2_HUMAN
NC score	0.006596 (rank : 48)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	870	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

WNT16_MOUSE
NC score	0.005621 (rank : 49)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	49	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QYS1	Gene names	Wnt16
Domain Architecture
Description	Protein Wnt-16 precursor.

ITF2_HUMAN
NC score	0.005601 (rank : 50)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

RGS3_HUMAN
NC score	0.004820 (rank : 51)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	1375	Shared Neighborhood Hits	13
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PLCB4_HUMAN
NC score	0.003018 (rank : 52)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	658	Shared Neighborhood Hits	5
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

HXC10_MOUSE
NC score	0.002628 (rank : 53)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	417	Shared Neighborhood Hits	5
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

HXC10_HUMAN
NC score	0.002275 (rank : 54)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	417	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYD6, O15219, O15220, Q9BVD5	Gene names	HOXC10
Domain Architecture
Description	Homeobox protein Hox-C10.

CT2NL_MOUSE
NC score	0.001236 (rank : 55)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	902	Shared Neighborhood Hits	9
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

HXB13_HUMAN
NC score	0.001187 (rank : 56)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	377	Shared Neighborhood Hits	4
SwissProt Accessions	Q92826, Q96QM4, Q99810	Gene names	HOXB13
Domain Architecture
Description	Homeobox protein Hox-B13.