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Network neighborhood for query Sequence : GT2D1_MOUSE

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GT2D1_MOUSE
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GT2D1_HUMAN
θ value	0 (rank : 1)	NC score	0.990907 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

GT2D1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

GTF2I_HUMAN
θ value	1.95407e-87 (rank : 3)	NC score	0.845763 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	151	Shared Neighborhood Hits	4
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

GTF2I_MOUSE
θ value	1.07224e-85 (rank : 4)	NC score	0.860955 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

K0329_HUMAN
θ value	0.279714 (rank : 5)	NC score	0.065048 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

ODP2_HUMAN
θ value	0.365318 (rank : 6)	NC score	0.039773 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

EVPL_MOUSE
θ value	1.38821 (rank : 7)	NC score	0.010004 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	952	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

FINC_HUMAN
θ value	1.38821 (rank : 8)	NC score	0.018037 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

GRB10_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.031905 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.032412 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

DUS3L_MOUSE
θ value	1.81305 (rank : 11)	NC score	0.026463 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XI1, Q3TZQ1, Q7TT12	Gene names	Dus3l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

PEG3_MOUSE
θ value	1.81305 (rank : 12)	NC score	0.007533 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	1101	Shared Neighborhood Hits	5
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

SASH1_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.020808 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

TRPM6_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.015449 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

FINC_MOUSE
θ value	2.36792 (rank : 15)	NC score	0.016939 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

NCA11_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.012940 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	661	Shared Neighborhood Hits	10
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

SELPL_MOUSE
θ value	2.36792 (rank : 17)	NC score	0.017994 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	588	Shared Neighborhood Hits	5
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SMAD9_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.025599 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	O15198, O14989	Gene names	SMAD9, MADH6, MADH9
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Madh6).

SMAD9_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.025386 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIW5, Q8CFF9	Gene names	Smad9, Madh8, Madh9, Smad8
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Smad8).

ZN397_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.000971 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	749	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NF99, Q9BRM2	Gene names	ZNF397, ZSCAN15
Domain Architecture
Description	Zinc finger protein 397 (Zinc finger and SCAN domain-containing protein 15).

BIN1_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.017318 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	283	Shared Neighborhood Hits	5
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

SMAD1_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.024759 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

MECP2_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.025168 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

ACD_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.039815 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

DSG1B_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.004295 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TSF1, Q7TQ60	Gene names	Dsg1b, Dsg5
Domain Architecture	No domain graphic available
Description	Desmoglein-1 beta precursor (Dsg1-beta) (Desmoglein-5).

GSC_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.007694 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	369	Shared Neighborhood Hits	3
SwissProt Accessions	P56915, Q86YR1	Gene names	GSC
Domain Architecture	No domain graphic available
Description	Homeobox protein goosecoid.

GSC_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.007693 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	368	Shared Neighborhood Hits	3
SwissProt Accessions	Q02591	Gene names	Gsc
Domain Architecture
Description	Homeobox protein goosecoid.

SYFA_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.025149 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y285, Q9NSD8, Q9Y4W8	Gene names	FARSLA, FARS, FARSA, FARSL
Domain Architecture
Description	Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (Phenylalanine--tRNA ligase alpha chain) (PheRS) (CML33).

ALO17_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.016098 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	317	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

RBNS5_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.011607 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	266	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

SMAD1_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.022476 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

GNAS1_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.005604 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	651	Shared Neighborhood Hits	8
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

MECP2_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.020086 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

RTP3_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.009415 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

TXND2_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.006276 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	828	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZDH14_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.005862 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZN3, Q5JS07, Q5JS08, Q6PHS4, Q8IZN2, Q9H7F1	Gene names	ZDHHC14
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 14) (DHHC-14) (NEW1 domain-containing protein) (NEW1CP).

Hits sorted by NC score

GT2D1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

GT2D1_HUMAN
NC score	0.990907 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

GTF2I_MOUSE
NC score	0.860955 (rank : 3)	θ value	1.07224e-85 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

GTF2I_HUMAN
NC score	0.845763 (rank : 4)	θ value	1.95407e-87 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	151	Shared Neighborhood Hits	4
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

K0329_HUMAN
NC score	0.065048 (rank : 5)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

ACD_HUMAN
NC score	0.039815 (rank : 6)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

ODP2_HUMAN
NC score	0.039773 (rank : 7)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

GRB10_MOUSE
NC score	0.032412 (rank : 8)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB10_HUMAN
NC score	0.031905 (rank : 9)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

DUS3L_MOUSE
NC score	0.026463 (rank : 10)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q91XI1, Q3TZQ1, Q7TT12	Gene names	Dus3l
Domain Architecture	No domain graphic available
Description	tRNA-dihydrouridine synthase 3-like (EC 1.-.-.-).

SMAD9_HUMAN
NC score	0.025599 (rank : 11)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	O15198, O14989	Gene names	SMAD9, MADH6, MADH9
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Madh6).

SMAD9_MOUSE
NC score	0.025386 (rank : 12)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIW5, Q8CFF9	Gene names	Smad9, Madh8, Madh9, Smad8
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Smad8).

MECP2_HUMAN
NC score	0.025168 (rank : 13)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	P51608, O15233	Gene names	MECP2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

SYFA_HUMAN
NC score	0.025149 (rank : 14)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y285, Q9NSD8, Q9Y4W8	Gene names	FARSLA, FARS, FARSA, FARSL
Domain Architecture
Description	Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (Phenylalanine--tRNA ligase alpha chain) (PheRS) (CML33).

SMAD1_MOUSE
NC score	0.024759 (rank : 15)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

SMAD1_HUMAN
NC score	0.022476 (rank : 16)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

SASH1_MOUSE
NC score	0.020808 (rank : 17)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	263	Shared Neighborhood Hits	3
SwissProt Accessions	P59808	Gene names	Sash1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1.

MECP2_MOUSE
NC score	0.020086 (rank : 18)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

FINC_HUMAN
NC score	0.018037 (rank : 19)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

SELPL_MOUSE
NC score	0.017994 (rank : 20)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	588	Shared Neighborhood Hits	5
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

BIN1_MOUSE
NC score	0.017318 (rank : 21)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	283	Shared Neighborhood Hits	5
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

FINC_MOUSE
NC score	0.016939 (rank : 22)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	309	Shared Neighborhood Hits	4
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

ALO17_HUMAN
NC score	0.016098 (rank : 23)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	317	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

TRPM6_HUMAN
NC score	0.015449 (rank : 24)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

NCA11_MOUSE
NC score	0.012940 (rank : 25)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	661	Shared Neighborhood Hits	10
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

RBNS5_MOUSE
NC score	0.011607 (rank : 26)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	266	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Y56, Q8K0L6, Q9CTW0	Gene names	Zfyve20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20).

EVPL_MOUSE
NC score	0.010004 (rank : 27)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	952	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

RTP3_MOUSE
NC score	0.009415 (rank : 28)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

GSC_HUMAN
NC score	0.007694 (rank : 29)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	369	Shared Neighborhood Hits	3
SwissProt Accessions	P56915, Q86YR1	Gene names	GSC
Domain Architecture	No domain graphic available
Description	Homeobox protein goosecoid.

GSC_MOUSE
NC score	0.007693 (rank : 30)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	368	Shared Neighborhood Hits	3
SwissProt Accessions	Q02591	Gene names	Gsc
Domain Architecture
Description	Homeobox protein goosecoid.

PEG3_MOUSE
NC score	0.007533 (rank : 31)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	1101	Shared Neighborhood Hits	5
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

TXND2_MOUSE
NC score	0.006276 (rank : 32)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	828	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZDH14_HUMAN
NC score	0.005862 (rank : 33)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IZN3, Q5JS07, Q5JS08, Q6PHS4, Q8IZN2, Q9H7F1	Gene names	ZDHHC14
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 14) (DHHC-14) (NEW1 domain-containing protein) (NEW1CP).

GNAS1_MOUSE
NC score	0.005604 (rank : 34)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	651	Shared Neighborhood Hits	8
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

DSG1B_MOUSE
NC score	0.004295 (rank : 35)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TSF1, Q7TQ60	Gene names	Dsg1b, Dsg5
Domain Architecture	No domain graphic available
Description	Desmoglein-1 beta precursor (Dsg1-beta) (Desmoglein-5).

ZN397_HUMAN
NC score	0.000971 (rank : 36)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	749	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NF99, Q9BRM2	Gene names	ZNF397, ZSCAN15
Domain Architecture
Description	Zinc finger protein 397 (Zinc finger and SCAN domain-containing protein 15).