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Network neighborhood for query Sequence : GTF2I_MOUSE

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GTF2I_MOUSE
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GTF2I_HUMAN
θ value	0 (rank : 1)	NC score	0.979415 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	151	Shared Neighborhood Hits	52
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

GTF2I_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

GT2D1_HUMAN
θ value	3.91911e-104 (rank : 3)	NC score	0.879435 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

GT2D1_MOUSE
θ value	1.07224e-85 (rank : 4)	NC score	0.860955 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

MORC3_HUMAN
θ value	0.0563607 (rank : 5)	NC score	0.050066 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	489	Shared Neighborhood Hits	8
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

ESX1L_HUMAN
θ value	0.62314 (rank : 6)	NC score	0.021403 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	498	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

IWS1_HUMAN
θ value	0.62314 (rank : 7)	NC score	0.042915 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NTKL_MOUSE
θ value	0.62314 (rank : 8)	NC score	0.043925 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	326	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

TBCD2_HUMAN
θ value	0.62314 (rank : 9)	NC score	0.042261 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	419	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

PP1R7_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.023157 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	256	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UM45, Q9CV31, Q9Z105	Gene names	Ppp1r7, Sds22
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22).

SEPT9_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.015943 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	706	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

AP3B2_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.033888 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	246	Shared Neighborhood Hits	10
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

HS105_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.024369 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	209	Shared Neighborhood Hits	11
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

MYST2_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.039799 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
θ value	1.06291 (rank : 15)	NC score	0.039884 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

CCD38_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.035228 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

SPRL1_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.035597 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	403	Shared Neighborhood Hits	17
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TOIP2_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.030196 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

CELR1_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.004847 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	613	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

JIP3_MOUSE
θ value	1.81305 (rank : 20)	NC score	0.022249 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

JPH4_MOUSE
θ value	1.81305 (rank : 21)	NC score	0.016792 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

ZN638_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.022418 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

AFF1_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.036245 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	351	Shared Neighborhood Hits	13
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

SHAN2_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.024946 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	346	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SRBS1_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.016695 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

AFF1_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.045095 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	506	Shared Neighborhood Hits	17
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ANR25_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.011637 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	398	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

DYNA_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.011918 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	1194	Shared Neighborhood Hits	14
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

IWS1_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.034724 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	1258	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYO15_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.009363 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	467	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NTKL_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.034776 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	266	Shared Neighborhood Hits	7
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

SOX13_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.016870 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	495	Shared Neighborhood Hits	13
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SSX3_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.024427 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q99909, O60223, Q5JQZ3	Gene names	SSX3
Domain Architecture
Description	Protein SSX3.

VGFR2_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.002417 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	1103	Shared Neighborhood Hits	6
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

ZAN_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.026271 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	679	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZCH14_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.032357 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

BAZ2B_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.021379 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	803	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

IF3X_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.033515 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O75153, Q6AHY2, Q6P3X7, Q6ZUG8, Q8N4U7, Q9BTA3, Q9H979	Gene names	KIAA0664
Domain Architecture	No domain graphic available
Description	Putative eukaryotic translation initiation factor 3 subunit (eIF-3).

MLL2_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.019786 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	1788	Shared Neighborhood Hits	28
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CLCA_HUMAN
θ value	5.27518 (rank : 40)	NC score	0.025560 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	P09496	Gene names	CLTA
Domain Architecture
Description	Clathrin light chain A (Lca).

CQ032_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.034873 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SYH2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf32 homolog.

CRTAP_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.019593 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	O75718	Gene names	CRTAP, CASP
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

CSPG2_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.009541 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	681	Shared Neighborhood Hits	8
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

DNL1_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.033833 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

JHD2C_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.016178 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

JHD3C_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.008607 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

LR37A_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.017314 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	720	Shared Neighborhood Hits	17
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

NOL6_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.016214 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R5K4, Q6PAN8, Q8C6V4, Q8R5K3, Q8VCG0, Q8WTY7	Gene names	Nol6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

OXRP_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.024341 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	544	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PP4R1_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.016279 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

WBS14_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.021911 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	273	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

AP3B2_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.035571 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	246	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

ASPP1_MOUSE
θ value	6.88961 (rank : 53)	NC score	0.012257 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	1244	Shared Neighborhood Hits	24
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

LUZP1_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.007665 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	940	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

NPFF2_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.001929 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	804	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5X5, Q96RV1, Q9NR49	Gene names	NPFFR2, GPR74, NPFF2, NPGPR
Domain Architecture
Description	Neuropeptide FF receptor 2 (Neuropeptide G-protein coupled receptor) (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77).

ROBO4_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.006587 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	364	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

SIP1_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.001743 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	870	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

SMN_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.028460 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

SYK_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.020966 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MN1	Gene names	Kars
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

GNAS1_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.005980 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	651	Shared Neighborhood Hits	9
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

K0256_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.011277 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

KLH11_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.005533 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVR0	Gene names	KLHL11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

KNTC2_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.008376 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	673	Shared Neighborhood Hits	7
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

LYN_HUMAN
θ value	8.99809 (rank : 64)	NC score	-0.000336 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	1022	Shared Neighborhood Hits	6
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MYST3_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.034355 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	772	Shared Neighborhood Hits	18
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NFH_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.007462 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	1242	Shared Neighborhood Hits	24
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SIP1_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.001496 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	832	Shared Neighborhood Hits	6
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

SRCH_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.046959 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TAF3_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.012008 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	568	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TITIN_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.011002 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	2923	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TRI44_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.011115 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	327	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

ZAN_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.010712 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	808	Shared Neighborhood Hits	9
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

GTF2I_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	72	Target Neighborhood Hits	72	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

GTF2I_HUMAN
NC score	0.979415 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	72	Target Neighborhood Hits	151	Shared Neighborhood Hits	52
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

GT2D1_HUMAN
NC score	0.879435 (rank : 3)	θ value	3.91911e-104 (rank : 3)
Query Neighborhood Hits	72	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

GT2D1_MOUSE
NC score	0.860955 (rank : 4)	θ value	1.07224e-85 (rank : 4)
Query Neighborhood Hits	72	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

MORC3_HUMAN
NC score	0.050066 (rank : 5)	θ value	0.0563607 (rank : 5)
Query Neighborhood Hits	72	Target Neighborhood Hits	489	Shared Neighborhood Hits	8
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

SRCH_HUMAN
NC score	0.046959 (rank : 6)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	72	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

AFF1_HUMAN
NC score	0.045095 (rank : 7)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	72	Target Neighborhood Hits	506	Shared Neighborhood Hits	17
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

NTKL_MOUSE
NC score	0.043925 (rank : 8)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	72	Target Neighborhood Hits	326	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

IWS1_HUMAN
NC score	0.042915 (rank : 9)	θ value	0.62314 (rank : 7)
Query Neighborhood Hits	72	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TBCD2_HUMAN
NC score	0.042261 (rank : 10)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	72	Target Neighborhood Hits	419	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

MYST2_MOUSE
NC score	0.039884 (rank : 11)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	72	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_HUMAN
NC score	0.039799 (rank : 12)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	72	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

AFF1_MOUSE
NC score	0.036245 (rank : 13)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	72	Target Neighborhood Hits	351	Shared Neighborhood Hits	13
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

SPRL1_MOUSE
NC score	0.035597 (rank : 14)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	72	Target Neighborhood Hits	403	Shared Neighborhood Hits	17
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

AP3B2_MOUSE
NC score	0.035571 (rank : 15)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	72	Target Neighborhood Hits	246	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

CCD38_HUMAN
NC score	0.035228 (rank : 16)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	72	Target Neighborhood Hits	287	Shared Neighborhood Hits	5
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CQ032_MOUSE
NC score	0.034873 (rank : 17)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	72	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SYH2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf32 homolog.

NTKL_HUMAN
NC score	0.034776 (rank : 18)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	72	Target Neighborhood Hits	266	Shared Neighborhood Hits	7
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

IWS1_MOUSE
NC score	0.034724 (rank : 19)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	72	Target Neighborhood Hits	1258	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYST3_HUMAN
NC score	0.034355 (rank : 20)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	72	Target Neighborhood Hits	772	Shared Neighborhood Hits	18
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

AP3B2_HUMAN
NC score	0.033888 (rank : 21)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	72	Target Neighborhood Hits	246	Shared Neighborhood Hits	10
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

DNL1_HUMAN
NC score	0.033833 (rank : 22)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	72	Target Neighborhood Hits	216	Shared Neighborhood Hits	9
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

IF3X_HUMAN
NC score	0.033515 (rank : 23)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	72	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O75153, Q6AHY2, Q6P3X7, Q6ZUG8, Q8N4U7, Q9BTA3, Q9H979	Gene names	KIAA0664
Domain Architecture	No domain graphic available
Description	Putative eukaryotic translation initiation factor 3 subunit (eIF-3).

ZCH14_HUMAN
NC score	0.032357 (rank : 24)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	72	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

TOIP2_MOUSE
NC score	0.030196 (rank : 25)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	72	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

SMN_HUMAN
NC score	0.028460 (rank : 26)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	72	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

ZAN_HUMAN
NC score	0.026271 (rank : 27)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	72	Target Neighborhood Hits	679	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CLCA_HUMAN
NC score	0.025560 (rank : 28)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	72	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	P09496	Gene names	CLTA
Domain Architecture
Description	Clathrin light chain A (Lca).

SHAN2_HUMAN
NC score	0.024946 (rank : 29)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	72	Target Neighborhood Hits	346	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SSX3_HUMAN
NC score	0.024427 (rank : 30)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	72	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	Q99909, O60223, Q5JQZ3	Gene names	SSX3
Domain Architecture
Description	Protein SSX3.

HS105_HUMAN
NC score	0.024369 (rank : 31)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	72	Target Neighborhood Hits	209	Shared Neighborhood Hits	11
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

OXRP_HUMAN
NC score	0.024341 (rank : 32)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	72	Target Neighborhood Hits	544	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PP1R7_MOUSE
NC score	0.023157 (rank : 33)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	72	Target Neighborhood Hits	256	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UM45, Q9CV31, Q9Z105	Gene names	Ppp1r7, Sds22
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22).

ZN638_HUMAN
NC score	0.022418 (rank : 34)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	72	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

JIP3_MOUSE
NC score	0.022249 (rank : 35)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	72	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

WBS14_HUMAN
NC score	0.021911 (rank : 36)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	72	Target Neighborhood Hits	273	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

ESX1L_HUMAN
NC score	0.021403 (rank : 37)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	72	Target Neighborhood Hits	498	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

BAZ2B_HUMAN
NC score	0.021379 (rank : 38)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	72	Target Neighborhood Hits	803	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

SYK_MOUSE
NC score	0.020966 (rank : 39)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	72	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MN1	Gene names	Kars
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

MLL2_HUMAN
NC score	0.019786 (rank : 40)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	72	Target Neighborhood Hits	1788	Shared Neighborhood Hits	28
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CRTAP_HUMAN
NC score	0.019593 (rank : 41)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	72	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	O75718	Gene names	CRTAP, CASP
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

LR37A_HUMAN
NC score	0.017314 (rank : 42)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	72	Target Neighborhood Hits	720	Shared Neighborhood Hits	17
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

SOX13_MOUSE
NC score	0.016870 (rank : 43)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	72	Target Neighborhood Hits	495	Shared Neighborhood Hits	13
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

JPH4_MOUSE
NC score	0.016792 (rank : 44)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	72	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q80WT0, Q8BMI1	Gene names	Jph4, Jphl1
Domain Architecture	No domain graphic available
Description	Junctophilin-4 (Junctophilin-like 1 protein).

SRBS1_MOUSE
NC score	0.016695 (rank : 45)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	72	Target Neighborhood Hits	409	Shared Neighborhood Hits	12
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

PP4R1_MOUSE
NC score	0.016279 (rank : 46)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	72	Target Neighborhood Hits	94	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

NOL6_MOUSE
NC score	0.016214 (rank : 47)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	72	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R5K4, Q6PAN8, Q8C6V4, Q8R5K3, Q8VCG0, Q8WTY7	Gene names	Nol6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

JHD2C_HUMAN
NC score	0.016178 (rank : 48)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	72	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

SEPT9_HUMAN
NC score	0.015943 (rank : 49)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	72	Target Neighborhood Hits	706	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ASPP1_MOUSE
NC score	0.012257 (rank : 50)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	72	Target Neighborhood Hits	1244	Shared Neighborhood Hits	24
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TAF3_HUMAN
NC score	0.012008 (rank : 51)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	72	Target Neighborhood Hits	568	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

DYNA_HUMAN
NC score	0.011918 (rank : 52)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	72	Target Neighborhood Hits	1194	Shared Neighborhood Hits	14
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

ANR25_MOUSE
NC score	0.011637 (rank : 53)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	72	Target Neighborhood Hits	398	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

K0256_MOUSE
NC score	0.011277 (rank : 54)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	72	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q6A098	Gene names	Kiaa0256
Domain Architecture	No domain graphic available
Description	Protein KIAA0256.

TRI44_MOUSE
NC score	0.011115 (rank : 55)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	72	Target Neighborhood Hits	327	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TITIN_HUMAN
NC score	0.011002 (rank : 56)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	72	Target Neighborhood Hits	2923	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZAN_MOUSE
NC score	0.010712 (rank : 57)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	72	Target Neighborhood Hits	808	Shared Neighborhood Hits	9
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CSPG2_HUMAN
NC score	0.009541 (rank : 58)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	72	Target Neighborhood Hits	681	Shared Neighborhood Hits	8
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

MYO15_MOUSE
NC score	0.009363 (rank : 59)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	72	Target Neighborhood Hits	467	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

JHD3C_HUMAN
NC score	0.008607 (rank : 60)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	72	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

KNTC2_HUMAN
NC score	0.008376 (rank : 61)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	72	Target Neighborhood Hits	673	Shared Neighborhood Hits	7
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

LUZP1_MOUSE
NC score	0.007665 (rank : 62)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	72	Target Neighborhood Hits	940	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

NFH_HUMAN
NC score	0.007462 (rank : 63)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	72	Target Neighborhood Hits	1242	Shared Neighborhood Hits	24
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ROBO4_HUMAN
NC score	0.006587 (rank : 64)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	72	Target Neighborhood Hits	364	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

GNAS1_MOUSE
NC score	0.005980 (rank : 65)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	72	Target Neighborhood Hits	651	Shared Neighborhood Hits	9
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

KLH11_HUMAN
NC score	0.005533 (rank : 66)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	72	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVR0	Gene names	KLHL11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

CELR1_HUMAN
NC score	0.004847 (rank : 67)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	72	Target Neighborhood Hits	613	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

VGFR2_HUMAN
NC score	0.002417 (rank : 68)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	72	Target Neighborhood Hits	1103	Shared Neighborhood Hits	6
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

NPFF2_HUMAN
NC score	0.001929 (rank : 69)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	72	Target Neighborhood Hits	804	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5X5, Q96RV1, Q9NR49	Gene names	NPFFR2, GPR74, NPFF2, NPGPR
Domain Architecture
Description	Neuropeptide FF receptor 2 (Neuropeptide G-protein coupled receptor) (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77).

SIP1_MOUSE
NC score	0.001743 (rank : 70)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	72	Target Neighborhood Hits	870	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

SIP1_HUMAN
NC score	0.001496 (rank : 71)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	72	Target Neighborhood Hits	832	Shared Neighborhood Hits	6
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

LYN_HUMAN
NC score	-0.000336 (rank : 72)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	72	Target Neighborhood Hits	1022	Shared Neighborhood Hits	6
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).