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Network neighborhood for query Sequence : SMN_HUMAN

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SMN_HUMAN
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMN_HUMAN
θ value	7.40825e-95 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

SMN_MOUSE
θ value	2.91321e-91 (rank : 2)	NC score	0.979949 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	P97801, O09092	Gene names	Smn1, Smn
Domain Architecture
Description	Survival motor neuron protein.

SPF30_HUMAN
θ value	1.80886e-08 (rank : 3)	NC score	0.522560 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	O75940	Gene names	SMNDC1, SMNR, SPF30
Domain Architecture
Description	Survival of motor neuron-related-splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain- containing protein 1).

SPF30_MOUSE
θ value	1.99992e-07 (rank : 4)	NC score	0.508031 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGT7, Q4QQL0	Gene names	Smndc1, Smnr, Spf30
Domain Architecture
Description	Survival of motor neuron-related-splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain- containing protein 1).

TDRD3_MOUSE
θ value	0.000121331 (rank : 5)	NC score	0.329306 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q91W18, Q8BZW6	Gene names	Tdrd3
Domain Architecture
Description	Tudor domain-containing protein 3.

TDRD3_HUMAN
θ value	0.000461057 (rank : 6)	NC score	0.313007 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.

CEL_HUMAN
θ value	0.0431538 (rank : 7)	NC score	0.057243 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	896	Shared Neighborhood Hits	15
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

DBND2_HUMAN
θ value	0.125558 (rank : 8)	NC score	0.100580 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQY9, Q9BQZ0, Q9BVL1, Q9H1F6, Q9NWZ0, Q9NY07, Q9NZ31	Gene names	DBNDD2, C20orf35
Domain Architecture
Description	Dysbindin domain-containing protein 2 (HSMNP1).

MYO15_HUMAN
θ value	0.21417 (rank : 9)	NC score	0.028413 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	671	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PKP4_MOUSE
θ value	0.21417 (rank : 10)	NC score	0.047338 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

INP5E_HUMAN
θ value	0.813845 (rank : 11)	NC score	0.055002 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	201	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

JHD2C_MOUSE
θ value	1.06291 (rank : 12)	NC score	0.029248 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

SC24C_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.039153 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	662	Shared Neighborhood Hits	10
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MAP1A_HUMAN
θ value	1.38821 (rank : 14)	NC score	0.033222 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	1626	Shared Neighborhood Hits	13
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NLGNX_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.035443 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

STK31_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.048546 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	570	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

SON_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.032738 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	1568	Shared Neighborhood Hits	21
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NFAC1_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.025327 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

PYGO1_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.047283 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

BCL9_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.037171 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	1008	Shared Neighborhood Hits	14
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

PKP4_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.041402 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

TITIN_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.008349 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	2923	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

K1802_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.019614 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	1596	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

FA47A_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.045423 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	451	Shared Neighborhood Hits	11
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

BOC_MOUSE
θ value	6.88961 (rank : 25)	NC score	0.008450 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	433	Shared Neighborhood Hits	4
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CD2_HUMAN
θ value	6.88961 (rank : 26)	NC score	0.018823 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	504	Shared Neighborhood Hits	5
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

GTF2I_HUMAN
θ value	6.88961 (rank : 27)	NC score	0.029285 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	151	Shared Neighborhood Hits	4
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

GTF2I_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.028460 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

NLGNY_HUMAN
θ value	6.88961 (rank : 29)	NC score	0.031971 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

PER2_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.014604 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PYGO1_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.039481 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0P5	Gene names	Pygo1
Domain Architecture
Description	Pygopus homolog 1.

TCGAP_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.012876 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	872	Shared Neighborhood Hits	8
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

UHRF1_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.012626 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	278	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

CK5P2_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.005468 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	1151	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

FMN2_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.037738 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	349	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

MTF2_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.013163 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

STK31_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.030548 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	474	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

TDRD1_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.059793 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MV1	Gene names	Tdrd1
Domain Architecture
Description	Tudor domain-containing protein 1.

UBP30_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.014475 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

Hits sorted by NC score

SMN_HUMAN
NC score	0.999962 (rank : 1)	θ value	7.40825e-95 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

SMN_MOUSE
NC score	0.979949 (rank : 2)	θ value	2.91321e-91 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	29	Shared Neighborhood Hits	17
SwissProt Accessions	P97801, O09092	Gene names	Smn1, Smn
Domain Architecture
Description	Survival motor neuron protein.

SPF30_HUMAN
NC score	0.522560 (rank : 3)	θ value	1.80886e-08 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	O75940	Gene names	SMNDC1, SMNR, SPF30
Domain Architecture
Description	Survival of motor neuron-related-splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain- containing protein 1).

SPF30_MOUSE
NC score	0.508031 (rank : 4)	θ value	1.99992e-07 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGT7, Q4QQL0	Gene names	Smndc1, Smnr, Spf30
Domain Architecture
Description	Survival of motor neuron-related-splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain- containing protein 1).

TDRD3_MOUSE
NC score	0.329306 (rank : 5)	θ value	0.000121331 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	Q91W18, Q8BZW6	Gene names	Tdrd3
Domain Architecture
Description	Tudor domain-containing protein 3.

TDRD3_HUMAN
NC score	0.313007 (rank : 6)	θ value	0.000461057 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.

DBND2_HUMAN
NC score	0.100580 (rank : 7)	θ value	0.125558 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BQY9, Q9BQZ0, Q9BVL1, Q9H1F6, Q9NWZ0, Q9NY07, Q9NZ31	Gene names	DBNDD2, C20orf35
Domain Architecture
Description	Dysbindin domain-containing protein 2 (HSMNP1).

TDRD1_MOUSE
NC score	0.059793 (rank : 8)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q99MV1	Gene names	Tdrd1
Domain Architecture
Description	Tudor domain-containing protein 1.

CEL_HUMAN
NC score	0.057243 (rank : 9)	θ value	0.0431538 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	896	Shared Neighborhood Hits	15
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

INP5E_HUMAN
NC score	0.055002 (rank : 10)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	201	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

STK31_HUMAN
NC score	0.048546 (rank : 11)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	570	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

PKP4_MOUSE
NC score	0.047338 (rank : 12)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	129	Shared Neighborhood Hits	4
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PYGO1_HUMAN
NC score	0.047283 (rank : 13)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3Y4	Gene names	PYGO1
Domain Architecture
Description	Pygopus homolog 1.

FA47A_HUMAN
NC score	0.045423 (rank : 14)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	451	Shared Neighborhood Hits	11
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

PKP4_HUMAN
NC score	0.041402 (rank : 15)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PYGO1_MOUSE
NC score	0.039481 (rank : 16)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0P5	Gene names	Pygo1
Domain Architecture
Description	Pygopus homolog 1.

SC24C_HUMAN
NC score	0.039153 (rank : 17)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	662	Shared Neighborhood Hits	10
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

FMN2_MOUSE
NC score	0.037738 (rank : 18)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	349	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

BCL9_HUMAN
NC score	0.037171 (rank : 19)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	1008	Shared Neighborhood Hits	14
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

NLGNX_HUMAN
NC score	0.035443 (rank : 20)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

MAP1A_HUMAN
NC score	0.033222 (rank : 21)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	1626	Shared Neighborhood Hits	13
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SON_HUMAN
NC score	0.032738 (rank : 22)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	1568	Shared Neighborhood Hits	21
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NLGNY_HUMAN
NC score	0.031971 (rank : 23)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

STK31_MOUSE
NC score	0.030548 (rank : 24)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	474	Shared Neighborhood Hits	5
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

GTF2I_HUMAN
NC score	0.029285 (rank : 25)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	151	Shared Neighborhood Hits	4
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

JHD2C_MOUSE
NC score	0.029248 (rank : 26)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

GTF2I_MOUSE
NC score	0.028460 (rank : 27)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

MYO15_HUMAN
NC score	0.028413 (rank : 28)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	671	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NFAC1_HUMAN
NC score	0.025327 (rank : 29)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	O95644, Q12865, Q15793	Gene names	NFATC1, NFAT2, NFATC
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

K1802_MOUSE
NC score	0.019614 (rank : 30)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	1596	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CD2_HUMAN
NC score	0.018823 (rank : 31)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	504	Shared Neighborhood Hits	5
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

PER2_MOUSE
NC score	0.014604 (rank : 32)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

UBP30_HUMAN
NC score	0.014475 (rank : 33)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

MTF2_HUMAN
NC score	0.013163 (rank : 34)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	119	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

TCGAP_HUMAN
NC score	0.012876 (rank : 35)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	872	Shared Neighborhood Hits	8
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

UHRF1_MOUSE
NC score	0.012626 (rank : 36)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	278	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

BOC_MOUSE
NC score	0.008450 (rank : 37)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	433	Shared Neighborhood Hits	4
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

TITIN_HUMAN
NC score	0.008349 (rank : 38)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	2923	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CK5P2_MOUSE
NC score	0.005468 (rank : 39)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	1151	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).