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Network neighborhood for query Sequence : GTF2I_HUMAN

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GTF2I_HUMAN
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GTF2I_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	151	Target Neighborhood Hits	151	Shared Neighborhood Hits	151
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

GTF2I_MOUSE
θ value	0 (rank : 2)	NC score	0.979415 (rank : 2)
Query Neighborhood Hits	151	Target Neighborhood Hits	72	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

GT2D1_HUMAN
θ value	2.71407e-105 (rank : 3)	NC score	0.865123 (rank : 3)
Query Neighborhood Hits	151	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

GT2D1_MOUSE
θ value	1.95407e-87 (rank : 4)	NC score	0.845763 (rank : 4)
Query Neighborhood Hits	151	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

TITIN_HUMAN
θ value	0.000461057 (rank : 5)	NC score	0.024632 (rank : 72)
Query Neighborhood Hits	151	Target Neighborhood Hits	2923	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

NFM_MOUSE
θ value	0.00509761 (rank : 6)	NC score	0.024916 (rank : 71)
Query Neighborhood Hits	151	Target Neighborhood Hits	1159	Shared Neighborhood Hits	35
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

AFF4_HUMAN
θ value	0.0193708 (rank : 7)	NC score	0.085431 (rank : 6)
Query Neighborhood Hits	151	Target Neighborhood Hits	611	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
θ value	0.0193708 (rank : 8)	NC score	0.082873 (rank : 9)
Query Neighborhood Hits	151	Target Neighborhood Hits	581	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

MYST3_HUMAN
θ value	0.0193708 (rank : 9)	NC score	0.058836 (rank : 15)
Query Neighborhood Hits	151	Target Neighborhood Hits	772	Shared Neighborhood Hits	44
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

ACINU_HUMAN
θ value	0.0252991 (rank : 10)	NC score	0.085063 (rank : 7)
Query Neighborhood Hits	151	Target Neighborhood Hits	828	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ACINU_MOUSE
θ value	0.0563607 (rank : 11)	NC score	0.071986 (rank : 12)
Query Neighborhood Hits	151	Target Neighborhood Hits	712	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFF1_HUMAN
θ value	0.0961366 (rank : 12)	NC score	0.084146 (rank : 8)
Query Neighborhood Hits	151	Target Neighborhood Hits	506	Shared Neighborhood Hits	32
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

MORC3_HUMAN
θ value	0.0961366 (rank : 13)	NC score	0.048747 (rank : 21)
Query Neighborhood Hits	151	Target Neighborhood Hits	489	Shared Neighborhood Hits	13
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

AP3B2_MOUSE
θ value	0.125558 (rank : 14)	NC score	0.048986 (rank : 20)
Query Neighborhood Hits	151	Target Neighborhood Hits	246	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

ATRX_HUMAN
θ value	0.163984 (rank : 15)	NC score	0.038710 (rank : 31)
Query Neighborhood Hits	151	Target Neighborhood Hits	842	Shared Neighborhood Hits	40
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ESX1L_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.022755 (rank : 81)
Query Neighborhood Hits	151	Target Neighborhood Hits	498	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

ZAN_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.034784 (rank : 42)
Query Neighborhood Hits	151	Target Neighborhood Hits	679	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ASPH_HUMAN
θ value	0.21417 (rank : 18)	NC score	0.072197 (rank : 11)
Query Neighborhood Hits	151	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

SRCH_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.066622 (rank : 14)
Query Neighborhood Hits	151	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

IWS1_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.089304 (rank : 5)
Query Neighborhood Hits	151	Target Neighborhood Hits	1241	Shared Neighborhood Hits	90
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DNL1_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.045028 (rank : 26)
Query Neighborhood Hits	151	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

MYCL1_MOUSE
θ value	0.47712 (rank : 22)	NC score	0.033424 (rank : 51)
Query Neighborhood Hits	151	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

NTKL_MOUSE
θ value	0.47712 (rank : 23)	NC score	0.045581 (rank : 25)
Query Neighborhood Hits	151	Target Neighborhood Hits	326	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

HS105_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.037456 (rank : 34)
Query Neighborhood Hits	151	Target Neighborhood Hits	209	Shared Neighborhood Hits	30
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

TBCD2_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.043932 (rank : 27)
Query Neighborhood Hits	151	Target Neighborhood Hits	419	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

ABL1_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.003040 (rank : 147)
Query Neighborhood Hits	151	Target Neighborhood Hits	1220	Shared Neighborhood Hits	17
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

AFAD_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.021774 (rank : 91)
Query Neighborhood Hits	151	Target Neighborhood Hits	689	Shared Neighborhood Hits	13
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

BAZ2B_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.033521 (rank : 48)
Query Neighborhood Hits	151	Target Neighborhood Hits	803	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CHD5_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.018541 (rank : 107)
Query Neighborhood Hits	151	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

MLL2_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.035630 (rank : 38)
Query Neighborhood Hits	151	Target Neighborhood Hits	1788	Shared Neighborhood Hits	60
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OXRP_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.042919 (rank : 28)
Query Neighborhood Hits	151	Target Neighborhood Hits	544	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

SYTL1_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.028133 (rank : 63)
Query Neighborhood Hits	151	Target Neighborhood Hits	314	Shared Neighborhood Hits	40
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

AMELY_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.035721 (rank : 37)
Query Neighborhood Hits	151	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q99218, Q6RWT1	Gene names	AMELY, AMGL, AMGY
Domain Architecture
Description	Amelogenin, Y isoform precursor.

CCD38_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.034275 (rank : 44)
Query Neighborhood Hits	151	Target Neighborhood Hits	287	Shared Neighborhood Hits	4
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CJ047_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.035031 (rank : 41)
Query Neighborhood Hits	151	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

FOXJ2_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.012558 (rank : 125)
Query Neighborhood Hits	151	Target Neighborhood Hits	239	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

IWS1_MOUSE
θ value	1.38821 (rank : 37)	NC score	0.081965 (rank : 10)
Query Neighborhood Hits	151	Target Neighborhood Hits	1258	Shared Neighborhood Hits	92
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MINT_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.038338 (rank : 32)
Query Neighborhood Hits	151	Target Neighborhood Hits	1291	Shared Neighborhood Hits	58
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYST2_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.051805 (rank : 18)
Query Neighborhood Hits	151	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
θ value	1.38821 (rank : 40)	NC score	0.051993 (rank : 17)
Query Neighborhood Hits	151	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

NXPH2_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.022248 (rank : 85)
Query Neighborhood Hits	151	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q61199, Q8BIN8	Gene names	Nxph2, Nph2
Domain Architecture	No domain graphic available
Description	Neurexophilin-2 precursor.

PCLO_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.028205 (rank : 62)
Query Neighborhood Hits	151	Target Neighborhood Hits	2275	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RPA1_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.023573 (rank : 77)
Query Neighborhood Hits	151	Target Neighborhood Hits	112	Shared Neighborhood Hits	9
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

SPEG_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.008028 (rank : 138)
Query Neighborhood Hits	151	Target Neighborhood Hits	1762	Shared Neighborhood Hits	36
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZFY1_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.003663 (rank : 146)
Query Neighborhood Hits	151	Target Neighborhood Hits	790	Shared Neighborhood Hits	15
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

AP3B2_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.047083 (rank : 23)
Query Neighborhood Hits	151	Target Neighborhood Hits	246	Shared Neighborhood Hits	22
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

HS105_MOUSE
θ value	1.81305 (rank : 47)	NC score	0.023883 (rank : 74)
Query Neighborhood Hits	151	Target Neighborhood Hits	129	Shared Neighborhood Hits	9
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

JIP3_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.025417 (rank : 68)
Query Neighborhood Hits	151	Target Neighborhood Hits	759	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

MAP1B_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.035276 (rank : 40)
Query Neighborhood Hits	151	Target Neighborhood Hits	977	Shared Neighborhood Hits	56
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

SET1A_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.034343 (rank : 43)
Query Neighborhood Hits	151	Target Neighborhood Hits	690	Shared Neighborhood Hits	39
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SSX3_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.025044 (rank : 70)
Query Neighborhood Hits	151	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q99909, O60223, Q5JQZ3	Gene names	SSX3
Domain Architecture
Description	Protein SSX3.

ZEP1_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.011458 (rank : 128)
Query Neighborhood Hits	151	Target Neighborhood Hits	1063	Shared Neighborhood Hits	33
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

ZFY19_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.026447 (rank : 66)
Query Neighborhood Hits	151	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

CNOT3_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.034250 (rank : 45)
Query Neighborhood Hits	151	Target Neighborhood Hits	425	Shared Neighborhood Hits	19
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.032568 (rank : 53)
Query Neighborhood Hits	151	Target Neighborhood Hits	504	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CTR9_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.033520 (rank : 49)
Query Neighborhood Hits	151	Target Neighborhood Hits	383	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CTR9_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.037478 (rank : 33)
Query Neighborhood Hits	151	Target Neighborhood Hits	427	Shared Neighborhood Hits	19
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

GSCR1_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.029371 (rank : 58)
Query Neighborhood Hits	151	Target Neighborhood Hits	674	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

IF2P_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.027129 (rank : 64)
Query Neighborhood Hits	151	Target Neighborhood Hits	889	Shared Neighborhood Hits	32
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

JIP1_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.022058 (rank : 87)
Query Neighborhood Hits	151	Target Neighborhood Hits	271	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

NDF1_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.014275 (rank : 122)
Query Neighborhood Hits	151	Target Neighborhood Hits	186	Shared Neighborhood Hits	10
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NUCL_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.018744 (rank : 105)
Query Neighborhood Hits	151	Target Neighborhood Hits	415	Shared Neighborhood Hits	24
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

SYNP2_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.020395 (rank : 96)
Query Neighborhood Hits	151	Target Neighborhood Hits	323	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

WNK1_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.006340 (rank : 141)
Query Neighborhood Hits	151	Target Neighborhood Hits	1179	Shared Neighborhood Hits	22
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

EP300_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.022036 (rank : 88)
Query Neighborhood Hits	151	Target Neighborhood Hits	821	Shared Neighborhood Hits	37
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GLU2B_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.025321 (rank : 69)
Query Neighborhood Hits	151	Target Neighborhood Hits	377	Shared Neighborhood Hits	19
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

PP1R7_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.019249 (rank : 102)
Query Neighborhood Hits	151	Target Neighborhood Hits	256	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UM45, Q9CV31, Q9Z105	Gene names	Ppp1r7, Sds22
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22).

SPRL1_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.046706 (rank : 24)
Query Neighborhood Hits	151	Target Neighborhood Hits	403	Shared Neighborhood Hits	41
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

SRRM1_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.035918 (rank : 36)
Query Neighborhood Hits	151	Target Neighborhood Hits	966	Shared Neighborhood Hits	52
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TCF8_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.004660 (rank : 144)
Query Neighborhood Hits	151	Target Neighborhood Hits	1057	Shared Neighborhood Hits	25
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

AFF1_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.067443 (rank : 13)
Query Neighborhood Hits	151	Target Neighborhood Hits	351	Shared Neighborhood Hits	21
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ANTR1_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.023735 (rank : 76)
Query Neighborhood Hits	151	Target Neighborhood Hits	128	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

ASPP1_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.018969 (rank : 104)
Query Neighborhood Hits	151	Target Neighborhood Hits	1244	Shared Neighborhood Hits	42
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CD68_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.022266 (rank : 84)
Query Neighborhood Hits	151	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	P34810, Q96BI7	Gene names	CD68
Domain Architecture
Description	Macrosialin precursor (GP110) (CD68 antigen).

IF3X_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.032667 (rank : 52)
Query Neighborhood Hits	151	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O75153, Q6AHY2, Q6P3X7, Q6ZUG8, Q8N4U7, Q9BTA3, Q9H979	Gene names	KIAA0664
Domain Architecture	No domain graphic available
Description	Putative eukaryotic translation initiation factor 3 subunit (eIF-3).

MYO15_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.011339 (rank : 130)
Query Neighborhood Hits	151	Target Neighborhood Hits	467	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYST3_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.047359 (rank : 22)
Query Neighborhood Hits	151	Target Neighborhood Hits	688	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NASP_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.049291 (rank : 19)
Query Neighborhood Hits	151	Target Neighborhood Hits	709	Shared Neighborhood Hits	51
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NCKX4_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.017089 (rank : 111)
Query Neighborhood Hits	151	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFF2, Q8N8U6, Q8NCX1, Q8NFF0, Q8NFF1	Gene names	SLC24A4, NCKX4
Domain Architecture
Description	Sodium/potassium/calcium exchanger 4 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 4) (Solute carrier family 24 member 4).

NOP14_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.024060 (rank : 73)
Query Neighborhood Hits	151	Target Neighborhood Hits	324	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

NSBP1_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.030167 (rank : 56)
Query Neighborhood Hits	151	Target Neighborhood Hits	251	Shared Neighborhood Hits	15
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PRG4_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.023220 (rank : 79)
Query Neighborhood Hits	151	Target Neighborhood Hits	624	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SF3A1_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.021776 (rank : 90)
Query Neighborhood Hits	151	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SHAN2_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.023882 (rank : 75)
Query Neighborhood Hits	151	Target Neighborhood Hits	346	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

XRCC1_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.032217 (rank : 54)
Query Neighborhood Hits	151	Target Neighborhood Hits	242	Shared Neighborhood Hits	32
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZCH14_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.030288 (rank : 55)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ANTR1_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.022068 (rank : 86)
Query Neighborhood Hits	151	Target Neighborhood Hits	143	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

CD248_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.010603 (rank : 133)
Query Neighborhood Hits	151	Target Neighborhood Hits	578	Shared Neighborhood Hits	20
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CLCA_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.025577 (rank : 67)
Query Neighborhood Hits	151	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	P09496	Gene names	CLTA
Domain Architecture
Description	Clathrin light chain A (Lca).

CN155_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.030165 (rank : 57)
Query Neighborhood Hits	151	Target Neighborhood Hits	385	Shared Neighborhood Hits	26
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CQ032_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.034099 (rank : 46)
Query Neighborhood Hits	151	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SYH2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf32 homolog.

CRTAP_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.019043 (rank : 103)
Query Neighborhood Hits	151	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	O75718	Gene names	CRTAP, CASP
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

CSPG2_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.010736 (rank : 132)
Query Neighborhood Hits	151	Target Neighborhood Hits	681	Shared Neighborhood Hits	24
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

IF39_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.020237 (rank : 97)
Query Neighborhood Hits	151	Target Neighborhood Hits	187	Shared Neighborhood Hits	10
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

JHD2C_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.019960 (rank : 101)
Query Neighborhood Hits	151	Target Neighborhood Hits	279	Shared Neighborhood Hits	28
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

MKL2_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.016399 (rank : 112)
Query Neighborhood Hits	151	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

NCKX4_MOUSE
θ value	5.27518 (rank : 97)	NC score	0.016216 (rank : 114)
Query Neighborhood Hits	151	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGQ8, Q8BLL5, Q8BLL7	Gene names	Slc24a4, Nckx4
Domain Architecture
Description	Sodium/potassium/calcium exchanger 4 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 4).

NFH_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.026550 (rank : 65)
Query Neighborhood Hits	151	Target Neighborhood Hits	1242	Shared Neighborhood Hits	46
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NOL3_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.033497 (rank : 50)
Query Neighborhood Hits	151	Target Neighborhood Hits	97	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

NTKL_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.035611 (rank : 39)
Query Neighborhood Hits	151	Target Neighborhood Hits	266	Shared Neighborhood Hits	7
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

RYR1_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.014581 (rank : 121)
Query Neighborhood Hits	151	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

SALL2_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.004110 (rank : 145)
Query Neighborhood Hits	151	Target Neighborhood Hits	836	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

SOX13_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.021286 (rank : 92)
Query Neighborhood Hits	151	Target Neighborhood Hits	495	Shared Neighborhood Hits	32
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SRCA_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.020081 (rank : 99)
Query Neighborhood Hits	151	Target Neighborhood Hits	212	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TRI44_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.018087 (rank : 108)
Query Neighborhood Hits	151	Target Neighborhood Hits	393	Shared Neighborhood Hits	17
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

VCX1_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.033828 (rank : 47)
Query Neighborhood Hits	151	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

ZFY2_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.002428 (rank : 149)
Query Neighborhood Hits	151	Target Neighborhood Hits	795	Shared Neighborhood Hits	14
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.

ATX2L_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.016112 (rank : 115)
Query Neighborhood Hits	151	Target Neighborhood Hits	443	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CLMN_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.013583 (rank : 123)
Query Neighborhood Hits	151	Target Neighborhood Hits	205	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

CTCF_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.000822 (rank : 151)
Query Neighborhood Hits	151	Target Neighborhood Hits	796	Shared Neighborhood Hits	16
SwissProt Accessions	Q61164	Gene names	Ctcf
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

DYNA_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.013343 (rank : 124)
Query Neighborhood Hits	151	Target Neighborhood Hits	1194	Shared Neighborhood Hits	27
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

KLH17_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.002836 (rank : 148)
Query Neighborhood Hits	151	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q6TDP3	Gene names	Klhl17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

LR37A_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.028396 (rank : 61)
Query Neighborhood Hits	151	Target Neighborhood Hits	720	Shared Neighborhood Hits	39
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MCM3_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.009428 (rank : 135)
Query Neighborhood Hits	151	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

MDN1_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.038817 (rank : 30)
Query Neighborhood Hits	151	Target Neighborhood Hits	662	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MOT8_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.011791 (rank : 126)
Query Neighborhood Hits	151	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P36021, Q7Z797	Gene names	SLC16A2, MCT8, XPCT
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

PHAR1_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.017296 (rank : 110)
Query Neighborhood Hits	151	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

PHAR1_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.017393 (rank : 109)
Query Neighborhood Hits	151	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

RFIP1_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.016228 (rank : 113)
Query Neighborhood Hits	151	Target Neighborhood Hits	236	Shared Neighborhood Hits	12
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RP1L1_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.022561 (rank : 83)
Query Neighborhood Hits	151	Target Neighborhood Hits	1072	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SMN_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.029285 (rank : 59)
Query Neighborhood Hits	151	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

SNAI_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.001072 (rank : 150)
Query Neighborhood Hits	151	Target Neighborhood Hits	708	Shared Neighborhood Hits	8
SwissProt Accessions	O95863, Q9P113, Q9UBP7, Q9UHH7	Gene names	SNAI1, SNAH
Domain Architecture	No domain graphic available
Description	Zinc finger protein SNAI1 (Protein snail homolog) (Protein sna).

SPT5H_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.020181 (rank : 98)
Query Neighborhood Hits	151	Target Neighborhood Hits	437	Shared Neighborhood Hits	29
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT6H_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.014744 (rank : 120)
Query Neighborhood Hits	151	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

SYK_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.020679 (rank : 94)
Query Neighborhood Hits	151	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MN1	Gene names	Kars
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

TCAL1_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.019981 (rank : 100)
Query Neighborhood Hits	151	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q921P9	Gene names	Tceal1
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 1 (TCEA-like protein 1) (Transcription elongation factor S-II protein-like 1).

U5S1_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.011496 (rank : 127)
Query Neighborhood Hits	151	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	O08810	Gene names	Eftud2, Snrp116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2).

WBS14_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.022846 (rank : 80)
Query Neighborhood Hits	151	Target Neighborhood Hits	273	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

AF17_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.009450 (rank : 134)
Query Neighborhood Hits	151	Target Neighborhood Hits	230	Shared Neighborhood Hits	13
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AHI1_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.004953 (rank : 143)
Query Neighborhood Hits	151	Target Neighborhood Hits	537	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

AP1G2_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.008967 (rank : 136)
Query Neighborhood Hits	151	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

CALX_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.011194 (rank : 131)
Query Neighborhood Hits	151	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

CCNK_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.014990 (rank : 117)
Query Neighborhood Hits	151	Target Neighborhood Hits	350	Shared Neighborhood Hits	21
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CENPB_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.020549 (rank : 95)
Query Neighborhood Hits	151	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

DAXX_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.023265 (rank : 78)
Query Neighborhood Hits	151	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

DIDO1_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.018693 (rank : 106)
Query Neighborhood Hits	151	Target Neighborhood Hits	960	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

FYB_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.014968 (rank : 118)
Query Neighborhood Hits	151	Target Neighborhood Hits	194	Shared Neighborhood Hits	14
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

IF4B_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.022006 (rank : 89)
Query Neighborhood Hits	151	Target Neighborhood Hits	368	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

KLH11_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.005992 (rank : 142)
Query Neighborhood Hits	151	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVR0	Gene names	KLHL11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

KNTC2_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.008935 (rank : 137)
Query Neighborhood Hits	151	Target Neighborhood Hits	673	Shared Neighborhood Hits	10
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

NACAM_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.039313 (rank : 29)
Query Neighborhood Hits	151	Target Neighborhood Hits	1866	Shared Neighborhood Hits	71
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NFM_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.020853 (rank : 93)
Query Neighborhood Hits	151	Target Neighborhood Hits	1328	Shared Neighborhood Hits	54
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NPFF2_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.000323 (rank : 152)
Query Neighborhood Hits	151	Target Neighborhood Hits	804	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5X5, Q96RV1, Q9NR49	Gene names	NPFFR2, GPR74, NPFF2, NPGPR
Domain Architecture
Description	Neuropeptide FF receptor 2 (Neuropeptide G-protein coupled receptor) (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77).

RNH2B_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.015290 (rank : 116)
Query Neighborhood Hits	151	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TBB1, Q6PK48, Q9HAF7	Gene names	RNASEH2B, DLEU8
Domain Architecture	No domain graphic available
Description	Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HI subunit B) (Aicardi-Goutieres syndrome 2 protein) (AGS2) (Deleted in lymphocytic leukemia 8).

RSF1_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.037293 (rank : 35)
Query Neighborhood Hits	151	Target Neighborhood Hits	539	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SI1L2_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.006496 (rank : 140)
Query Neighborhood Hits	151	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SRCA_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.022649 (rank : 82)
Query Neighborhood Hits	151	Target Neighborhood Hits	380	Shared Neighborhood Hits	27
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TF3C1_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.011364 (rank : 129)
Query Neighborhood Hits	151	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

TRDN_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.028875 (rank : 60)
Query Neighborhood Hits	151	Target Neighborhood Hits	542	Shared Neighborhood Hits	23
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ZAN_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.014927 (rank : 119)
Query Neighborhood Hits	151	Target Neighborhood Hits	808	Shared Neighborhood Hits	10
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZO1_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.007779 (rank : 139)
Query Neighborhood Hits	151	Target Neighborhood Hits	453	Shared Neighborhood Hits	19
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

TXND2_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.055036 (rank : 16)
Query Neighborhood Hits	151	Target Neighborhood Hits	793	Shared Neighborhood Hits	69
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

Hits sorted by NC score

GTF2I_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	151	Target Neighborhood Hits	151	Shared Neighborhood Hits	151
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

GTF2I_MOUSE
NC score	0.979415 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	151	Target Neighborhood Hits	72	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

GT2D1_HUMAN
NC score	0.865123 (rank : 3)	θ value	2.71407e-105 (rank : 3)
Query Neighborhood Hits	151	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

GT2D1_MOUSE
NC score	0.845763 (rank : 4)	θ value	1.95407e-87 (rank : 4)
Query Neighborhood Hits	151	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

IWS1_HUMAN
NC score	0.089304 (rank : 5)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	151	Target Neighborhood Hits	1241	Shared Neighborhood Hits	90
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AFF4_HUMAN
NC score	0.085431 (rank : 6)	θ value	0.0193708 (rank : 7)
Query Neighborhood Hits	151	Target Neighborhood Hits	611	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ACINU_HUMAN
NC score	0.085063 (rank : 7)	θ value	0.0252991 (rank : 10)
Query Neighborhood Hits	151	Target Neighborhood Hits	828	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFF1_HUMAN
NC score	0.084146 (rank : 8)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	151	Target Neighborhood Hits	506	Shared Neighborhood Hits	32
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AFF4_MOUSE
NC score	0.082873 (rank : 9)	θ value	0.0193708 (rank : 8)
Query Neighborhood Hits	151	Target Neighborhood Hits	581	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

IWS1_MOUSE
NC score	0.081965 (rank : 10)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	151	Target Neighborhood Hits	1258	Shared Neighborhood Hits	92
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ASPH_HUMAN
NC score	0.072197 (rank : 11)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	151	Target Neighborhood Hits	158	Shared Neighborhood Hits	24
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

ACINU_MOUSE
NC score	0.071986 (rank : 12)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	151	Target Neighborhood Hits	712	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFF1_MOUSE
NC score	0.067443 (rank : 13)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	151	Target Neighborhood Hits	351	Shared Neighborhood Hits	21
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

SRCH_HUMAN
NC score	0.066622 (rank : 14)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	151	Target Neighborhood Hits	225	Shared Neighborhood Hits	12
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

MYST3_HUMAN
NC score	0.058836 (rank : 15)	θ value	0.0193708 (rank : 9)
Query Neighborhood Hits	151	Target Neighborhood Hits	772	Shared Neighborhood Hits	44
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

TXND2_HUMAN
NC score	0.055036 (rank : 16)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	151	Target Neighborhood Hits	793	Shared Neighborhood Hits	69
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MYST2_MOUSE
NC score	0.051993 (rank : 17)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	151	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_HUMAN
NC score	0.051805 (rank : 18)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	151	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

NASP_HUMAN
NC score	0.049291 (rank : 19)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	151	Target Neighborhood Hits	709	Shared Neighborhood Hits	51
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

AP3B2_MOUSE
NC score	0.048986 (rank : 20)	θ value	0.125558 (rank : 14)
Query Neighborhood Hits	151	Target Neighborhood Hits	246	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

MORC3_HUMAN
NC score	0.048747 (rank : 21)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	151	Target Neighborhood Hits	489	Shared Neighborhood Hits	13
SwissProt Accessions	Q14149, Q9UEZ2	Gene names	MORC3, KIAA0136, ZCWCC3
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 3 (Zinc finger CW-type coiled- coil domain protein 3).

MYST3_MOUSE
NC score	0.047359 (rank : 22)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	151	Target Neighborhood Hits	688	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

AP3B2_HUMAN
NC score	0.047083 (rank : 23)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	151	Target Neighborhood Hits	246	Shared Neighborhood Hits	22
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

SPRL1_MOUSE
NC score	0.046706 (rank : 24)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	151	Target Neighborhood Hits	403	Shared Neighborhood Hits	41
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

NTKL_MOUSE
NC score	0.045581 (rank : 25)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	151	Target Neighborhood Hits	326	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

DNL1_HUMAN
NC score	0.045028 (rank : 26)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	151	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

TBCD2_HUMAN
NC score	0.043932 (rank : 27)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	151	Target Neighborhood Hits	419	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

OXRP_HUMAN
NC score	0.042919 (rank : 28)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	151	Target Neighborhood Hits	544	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

NACAM_MOUSE
NC score	0.039313 (rank : 29)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	151	Target Neighborhood Hits	1866	Shared Neighborhood Hits	71
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MDN1_HUMAN
NC score	0.038817 (rank : 30)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	151	Target Neighborhood Hits	662	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

ATRX_HUMAN
NC score	0.038710 (rank : 31)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	151	Target Neighborhood Hits	842	Shared Neighborhood Hits	40
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

MINT_HUMAN
NC score	0.038338 (rank : 32)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	151	Target Neighborhood Hits	1291	Shared Neighborhood Hits	58
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CTR9_MOUSE
NC score	0.037478 (rank : 33)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	151	Target Neighborhood Hits	427	Shared Neighborhood Hits	19
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

HS105_HUMAN
NC score	0.037456 (rank : 34)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	151	Target Neighborhood Hits	209	Shared Neighborhood Hits	30
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

RSF1_HUMAN
NC score	0.037293 (rank : 35)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	151	Target Neighborhood Hits	539	Shared Neighborhood Hits	37
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SRRM1_MOUSE
NC score	0.035918 (rank : 36)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	151	Target Neighborhood Hits	966	Shared Neighborhood Hits	52
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

AMELY_HUMAN
NC score	0.035721 (rank : 37)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	151	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q99218, Q6RWT1	Gene names	AMELY, AMGL, AMGY
Domain Architecture
Description	Amelogenin, Y isoform precursor.

MLL2_HUMAN
NC score	0.035630 (rank : 38)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	151	Target Neighborhood Hits	1788	Shared Neighborhood Hits	60
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

NTKL_HUMAN
NC score	0.035611 (rank : 39)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	151	Target Neighborhood Hits	266	Shared Neighborhood Hits	7
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

MAP1B_MOUSE
NC score	0.035276 (rank : 40)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	151	Target Neighborhood Hits	977	Shared Neighborhood Hits	56
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CJ047_HUMAN
NC score	0.035031 (rank : 41)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	151	Target Neighborhood Hits	164	Shared Neighborhood Hits	11
SwissProt Accessions	Q86WR7, Q5W0J9, Q5W0K0, Q5W0K1, Q5W0K2, Q6PJC8, Q8N317	Gene names	C10orf47
Domain Architecture	No domain graphic available
Description	Protein C10orf47.

ZAN_HUMAN
NC score	0.034784 (rank : 42)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	151	Target Neighborhood Hits	679	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

SET1A_HUMAN
NC score	0.034343 (rank : 43)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	151	Target Neighborhood Hits	690	Shared Neighborhood Hits	39
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

CCD38_HUMAN
NC score	0.034275 (rank : 44)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	151	Target Neighborhood Hits	287	Shared Neighborhood Hits	4
SwissProt Accessions	Q502W7, Q8N835	Gene names	CCDC38
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 38.

CNOT3_HUMAN
NC score	0.034250 (rank : 45)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	151	Target Neighborhood Hits	425	Shared Neighborhood Hits	19
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CQ032_MOUSE
NC score	0.034099 (rank : 46)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	151	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SYH2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf32 homolog.

VCX1_HUMAN
NC score	0.033828 (rank : 47)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	151	Target Neighborhood Hits	129	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H320, Q9P0H3	Gene names	VCX, VCX1, VCX10R, VCXB1
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 1 (VCX-B1 protein) (Variably charged protein X-B1) (Variable charge protein on X with ten repeats) (VCX- 10r).

BAZ2B_HUMAN
NC score	0.033521 (rank : 48)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	151	Target Neighborhood Hits	803	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CTR9_HUMAN
NC score	0.033520 (rank : 49)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	151	Target Neighborhood Hits	383	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

NOL3_MOUSE
NC score	0.033497 (rank : 50)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	151	Target Neighborhood Hits	97	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

MYCL1_MOUSE
NC score	0.033424 (rank : 51)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	151	Target Neighborhood Hits	123	Shared Neighborhood Hits	8
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

IF3X_HUMAN
NC score	0.032667 (rank : 52)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	151	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	O75153, Q6AHY2, Q6P3X7, Q6ZUG8, Q8N4U7, Q9BTA3, Q9H979	Gene names	KIAA0664
Domain Architecture	No domain graphic available
Description	Putative eukaryotic translation initiation factor 3 subunit (eIF-3).

CNOT3_MOUSE
NC score	0.032568 (rank : 53)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	151	Target Neighborhood Hits	504	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

XRCC1_MOUSE
NC score	0.032217 (rank : 54)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	151	Target Neighborhood Hits	242	Shared Neighborhood Hits	32
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

ZCH14_HUMAN
NC score	0.030288 (rank : 55)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

NSBP1_HUMAN
NC score	0.030167 (rank : 56)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	151	Target Neighborhood Hits	251	Shared Neighborhood Hits	15
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

CN155_HUMAN
NC score	0.030165 (rank : 57)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	151	Target Neighborhood Hits	385	Shared Neighborhood Hits	26
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

GSCR1_HUMAN
NC score	0.029371 (rank : 58)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	151	Target Neighborhood Hits	674	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SMN_HUMAN
NC score	0.029285 (rank : 59)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	151	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

TRDN_HUMAN
NC score	0.028875 (rank : 60)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	151	Target Neighborhood Hits	542	Shared Neighborhood Hits	23
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

LR37A_HUMAN
NC score	0.028396 (rank : 61)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	151	Target Neighborhood Hits	720	Shared Neighborhood Hits	39
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

PCLO_MOUSE
NC score	0.028205 (rank : 62)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	151	Target Neighborhood Hits	2275	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SYTL1_MOUSE
NC score	0.028133 (rank : 63)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	151	Target Neighborhood Hits	314	Shared Neighborhood Hits	40
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

IF2P_HUMAN
NC score	0.027129 (rank : 64)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	151	Target Neighborhood Hits	889	Shared Neighborhood Hits	32
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NFH_HUMAN
NC score	0.026550 (rank : 65)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	151	Target Neighborhood Hits	1242	Shared Neighborhood Hits	46
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ZFY19_HUMAN
NC score	0.026447 (rank : 66)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	151	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	Q96K21, Q86WC2, Q8WU96	Gene names	ZFYVE19, MPFYVE
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 19 (MLL partner containing FYVE domain).

CLCA_HUMAN
NC score	0.025577 (rank : 67)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	151	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	P09496	Gene names	CLTA
Domain Architecture
Description	Clathrin light chain A (Lca).

JIP3_MOUSE
NC score	0.025417 (rank : 68)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	151	Target Neighborhood Hits	759	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

GLU2B_HUMAN
NC score	0.025321 (rank : 69)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	151	Target Neighborhood Hits	377	Shared Neighborhood Hits	19
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

SSX3_HUMAN
NC score	0.025044 (rank : 70)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	151	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q99909, O60223, Q5JQZ3	Gene names	SSX3
Domain Architecture
Description	Protein SSX3.

NFM_MOUSE
NC score	0.024916 (rank : 71)	θ value	0.00509761 (rank : 6)
Query Neighborhood Hits	151	Target Neighborhood Hits	1159	Shared Neighborhood Hits	35
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

TITIN_HUMAN
NC score	0.024632 (rank : 72)	θ value	0.000461057 (rank : 5)
Query Neighborhood Hits	151	Target Neighborhood Hits	2923	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

NOP14_MOUSE
NC score	0.024060 (rank : 73)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	151	Target Neighborhood Hits	324	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R3N1	Gene names	Nop14
Domain Architecture	No domain graphic available
Description	Probable nucleolar complex protein 14.

HS105_MOUSE
NC score	0.023883 (rank : 74)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	151	Target Neighborhood Hits	129	Shared Neighborhood Hits	9
SwissProt Accessions	Q61699, Q3TNS2, Q3UIY8, Q62578, Q62579, Q6A0A5, Q8C430, Q8VCW6	Gene names	Hsph1, Hsp105, Hsp110, Kiaa0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock-related 100 kDa protein E7I) (HSP-E7I) (Heat shock 110 kDa protein) (42 degrees C-HSP).

SHAN2_HUMAN
NC score	0.023882 (rank : 75)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	151	Target Neighborhood Hits	346	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

ANTR1_HUMAN
NC score	0.023735 (rank : 76)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	151	Target Neighborhood Hits	128	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H6X2, Q96P02, Q9NVP3	Gene names	ANTXR1, ATR, TEM8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

RPA1_MOUSE
NC score	0.023573 (rank : 77)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	151	Target Neighborhood Hits	112	Shared Neighborhood Hits	9
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

DAXX_HUMAN
NC score	0.023265 (rank : 78)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	151	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

PRG4_MOUSE
NC score	0.023220 (rank : 79)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	151	Target Neighborhood Hits	624	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WBS14_HUMAN
NC score	0.022846 (rank : 80)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	151	Target Neighborhood Hits	273	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

ESX1L_HUMAN
NC score	0.022755 (rank : 81)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	151	Target Neighborhood Hits	498	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

SRCA_HUMAN
NC score	0.022649 (rank : 82)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	151	Target Neighborhood Hits	380	Shared Neighborhood Hits	27
SwissProt Accessions	Q86TD4	Gene names	SRL
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

RP1L1_HUMAN
NC score	0.022561 (rank : 83)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	151	Target Neighborhood Hits	1072	Shared Neighborhood Hits	47
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CD68_HUMAN
NC score	0.022266 (rank : 84)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	151	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	P34810, Q96BI7	Gene names	CD68
Domain Architecture
Description	Macrosialin precursor (GP110) (CD68 antigen).

NXPH2_MOUSE
NC score	0.022248 (rank : 85)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	151	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q61199, Q8BIN8	Gene names	Nxph2, Nph2
Domain Architecture	No domain graphic available
Description	Neurexophilin-2 precursor.

ANTR1_MOUSE
NC score	0.022068 (rank : 86)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	151	Target Neighborhood Hits	143	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CZ52	Gene names	Antxr1, Atr, Tem8
Domain Architecture
Description	Anthrax toxin receptor 1 precursor (Tumor endothelial marker 8).

JIP1_HUMAN
NC score	0.022058 (rank : 87)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	151	Target Neighborhood Hits	271	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

EP300_HUMAN
NC score	0.022036 (rank : 88)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	151	Target Neighborhood Hits	821	Shared Neighborhood Hits	37
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

IF4B_MOUSE
NC score	0.022006 (rank : 89)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	151	Target Neighborhood Hits	368	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

SF3A1_MOUSE
NC score	0.021776 (rank : 90)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	151	Target Neighborhood Hits	198	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

AFAD_HUMAN
NC score	0.021774 (rank : 91)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	151	Target Neighborhood Hits	689	Shared Neighborhood Hits	13
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

SOX13_MOUSE
NC score	0.021286 (rank : 92)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	151	Target Neighborhood Hits	495	Shared Neighborhood Hits	32
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

NFM_HUMAN
NC score	0.020853 (rank : 93)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	151	Target Neighborhood Hits	1328	Shared Neighborhood Hits	54
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

SYK_MOUSE
NC score	0.020679 (rank : 94)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	151	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MN1	Gene names	Kars
Domain Architecture
Description	Lysyl-tRNA synthetase (EC 6.1.1.6) (Lysine--tRNA ligase) (LysRS).

CENPB_MOUSE
NC score	0.020549 (rank : 95)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	151	Target Neighborhood Hits	163	Shared Neighborhood Hits	15
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

SYNP2_HUMAN
NC score	0.020395 (rank : 96)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	151	Target Neighborhood Hits	323	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UMS6, Q9UK89	Gene names	SYNPO2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin) (Genethonin 2).

IF39_HUMAN
NC score	0.020237 (rank : 97)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	151	Target Neighborhood Hits	187	Shared Neighborhood Hits	10
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

SPT5H_MOUSE
NC score	0.020181 (rank : 98)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	151	Target Neighborhood Hits	437	Shared Neighborhood Hits	29
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SRCA_MOUSE
NC score	0.020081 (rank : 99)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	151	Target Neighborhood Hits	212	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TCAL1_MOUSE
NC score	0.019981 (rank : 100)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	151	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q921P9	Gene names	Tceal1
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 1 (TCEA-like protein 1) (Transcription elongation factor S-II protein-like 1).

JHD2C_HUMAN
NC score	0.019960 (rank : 101)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	151	Target Neighborhood Hits	279	Shared Neighborhood Hits	28
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

PP1R7_MOUSE
NC score	0.019249 (rank : 102)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	151	Target Neighborhood Hits	256	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UM45, Q9CV31, Q9Z105	Gene names	Ppp1r7, Sds22
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22).

CRTAP_HUMAN
NC score	0.019043 (rank : 103)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	151	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	O75718	Gene names	CRTAP, CASP
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

ASPP1_MOUSE
NC score	0.018969 (rank : 104)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	151	Target Neighborhood Hits	1244	Shared Neighborhood Hits	42
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

NUCL_HUMAN
NC score	0.018744 (rank : 105)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	151	Target Neighborhood Hits	415	Shared Neighborhood Hits	24
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

DIDO1_HUMAN
NC score	0.018693 (rank : 106)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	151	Target Neighborhood Hits	960	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

CHD5_HUMAN
NC score	0.018541 (rank : 107)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	151	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

TRI44_HUMAN
NC score	0.018087 (rank : 108)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	151	Target Neighborhood Hits	393	Shared Neighborhood Hits	17
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

PHAR1_MOUSE
NC score	0.017393 (rank : 109)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	151	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

PHAR1_HUMAN
NC score	0.017296 (rank : 110)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	151	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

NCKX4_HUMAN
NC score	0.017089 (rank : 111)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	151	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFF2, Q8N8U6, Q8NCX1, Q8NFF0, Q8NFF1	Gene names	SLC24A4, NCKX4
Domain Architecture
Description	Sodium/potassium/calcium exchanger 4 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 4) (Solute carrier family 24 member 4).

MKL2_HUMAN
NC score	0.016399 (rank : 112)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	151	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

RFIP1_HUMAN
NC score	0.016228 (rank : 113)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	151	Target Neighborhood Hits	236	Shared Neighborhood Hits	12
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

NCKX4_MOUSE
NC score	0.016216 (rank : 114)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	151	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGQ8, Q8BLL5, Q8BLL7	Gene names	Slc24a4, Nckx4
Domain Architecture
Description	Sodium/potassium/calcium exchanger 4 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 4).

ATX2L_HUMAN
NC score	0.016112 (rank : 115)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	151	Target Neighborhood Hits	443	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

RNH2B_HUMAN
NC score	0.015290 (rank : 116)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	151	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TBB1, Q6PK48, Q9HAF7	Gene names	RNASEH2B, DLEU8
Domain Architecture	No domain graphic available
Description	Ribonuclease H2 subunit B (RNase H2 subunit B) (Ribonuclease HI subunit B) (Aicardi-Goutieres syndrome 2 protein) (AGS2) (Deleted in lymphocytic leukemia 8).

CCNK_MOUSE
NC score	0.014990 (rank : 117)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	151	Target Neighborhood Hits	350	Shared Neighborhood Hits	21
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

FYB_MOUSE
NC score	0.014968 (rank : 118)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	151	Target Neighborhood Hits	194	Shared Neighborhood Hits	14
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

ZAN_MOUSE
NC score	0.014927 (rank : 119)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	151	Target Neighborhood Hits	808	Shared Neighborhood Hits	10
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

SPT6H_HUMAN
NC score	0.014744 (rank : 120)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	151	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

RYR1_HUMAN
NC score	0.014581 (rank : 121)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	151	Target Neighborhood Hits	303	Shared Neighborhood Hits	20
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

NDF1_HUMAN
NC score	0.014275 (rank : 122)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	151	Target Neighborhood Hits	186	Shared Neighborhood Hits	10
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

CLMN_HUMAN
NC score	0.013583 (rank : 123)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	151	Target Neighborhood Hits	205	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

DYNA_HUMAN
NC score	0.013343 (rank : 124)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	151	Target Neighborhood Hits	1194	Shared Neighborhood Hits	27
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

FOXJ2_HUMAN
NC score	0.012558 (rank : 125)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	151	Target Neighborhood Hits	239	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

MOT8_HUMAN
NC score	0.011791 (rank : 126)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	151	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	P36021, Q7Z797	Gene names	SLC16A2, MCT8, XPCT
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

U5S1_MOUSE
NC score	0.011496 (rank : 127)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	151	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	O08810	Gene names	Eftud2, Snrp116
Domain Architecture
Description	116 kDa U5 small nuclear ribonucleoprotein component (U5 snRNP- specific protein, 116 kDa) (U5-116 kDa) (Elongation factor Tu GTP- binding domain protein 2).

ZEP1_MOUSE
NC score	0.011458 (rank : 128)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	151	Target Neighborhood Hits	1063	Shared Neighborhood Hits	33
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

TF3C1_HUMAN
NC score	0.011364 (rank : 129)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	151	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

MYO15_MOUSE
NC score	0.011339 (rank : 130)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	151	Target Neighborhood Hits	467	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CALX_MOUSE
NC score	0.011194 (rank : 131)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	151	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

CSPG2_HUMAN
NC score	0.010736 (rank : 132)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	151	Target Neighborhood Hits	681	Shared Neighborhood Hits	24
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CD248_MOUSE
NC score	0.010603 (rank : 133)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	151	Target Neighborhood Hits	578	Shared Neighborhood Hits	20
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

AF17_HUMAN
NC score	0.009450 (rank : 134)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	151	Target Neighborhood Hits	230	Shared Neighborhood Hits	13
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

MCM3_HUMAN
NC score	0.009428 (rank : 135)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	151	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	P25205, Q92660, Q9BTR3, Q9NUE7	Gene names	MCM3
Domain Architecture
Description	DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme-associated protein P1) (RLF subunit beta) (P102 protein) (P1-MCM3).

AP1G2_MOUSE
NC score	0.008967 (rank : 136)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	151	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

KNTC2_HUMAN
NC score	0.008935 (rank : 137)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	151	Target Neighborhood Hits	673	Shared Neighborhood Hits	10
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

SPEG_HUMAN
NC score	0.008028 (rank : 138)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	151	Target Neighborhood Hits	1762	Shared Neighborhood Hits	36
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZO1_MOUSE
NC score	0.007779 (rank : 139)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	151	Target Neighborhood Hits	453	Shared Neighborhood Hits	19
SwissProt Accessions	P39447	Gene names	Tjp1, Zo1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

SI1L2_HUMAN
NC score	0.006496 (rank : 140)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	151	Target Neighborhood Hits	131	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

WNK1_MOUSE
NC score	0.006340 (rank : 141)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	151	Target Neighborhood Hits	1179	Shared Neighborhood Hits	22
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

KLH11_HUMAN
NC score	0.005992 (rank : 142)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	151	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NVR0	Gene names	KLHL11
Domain Architecture	No domain graphic available
Description	Kelch-like protein 11 precursor.

AHI1_HUMAN
NC score	0.004953 (rank : 143)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	151	Target Neighborhood Hits	537	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

TCF8_HUMAN
NC score	0.004660 (rank : 144)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	151	Target Neighborhood Hits	1057	Shared Neighborhood Hits	25
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

SALL2_MOUSE
NC score	0.004110 (rank : 145)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	151	Target Neighborhood Hits	836	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

ZFY1_MOUSE
NC score	0.003663 (rank : 146)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	151	Target Neighborhood Hits	790	Shared Neighborhood Hits	15
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

ABL1_HUMAN
NC score	0.003040 (rank : 147)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	151	Target Neighborhood Hits	1220	Shared Neighborhood Hits	17
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

KLH17_MOUSE
NC score	0.002836 (rank : 148)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	151	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q6TDP3	Gene names	Klhl17
Domain Architecture	No domain graphic available
Description	Kelch-like protein 17 (Actinfilin).

ZFY2_MOUSE
NC score	0.002428 (rank : 149)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	151	Target Neighborhood Hits	795	Shared Neighborhood Hits	14
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.

SNAI_HUMAN
NC score	0.001072 (rank : 150)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	151	Target Neighborhood Hits	708	Shared Neighborhood Hits	8
SwissProt Accessions	O95863, Q9P113, Q9UBP7, Q9UHH7	Gene names	SNAI1, SNAH
Domain Architecture	No domain graphic available
Description	Zinc finger protein SNAI1 (Protein snail homolog) (Protein sna).

CTCF_MOUSE
NC score	0.000822 (rank : 151)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	151	Target Neighborhood Hits	796	Shared Neighborhood Hits	16
SwissProt Accessions	Q61164	Gene names	Ctcf
Domain Architecture
Description	Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein).

NPFF2_HUMAN
NC score	0.000323 (rank : 152)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	151	Target Neighborhood Hits	804	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5X5, Q96RV1, Q9NR49	Gene names	NPFFR2, GPR74, NPFF2, NPGPR
Domain Architecture
Description	Neuropeptide FF receptor 2 (Neuropeptide G-protein coupled receptor) (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77).