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Network neighborhood for query Sequence : GT2D1_HUMAN

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GT2D1_HUMAN
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GT2D1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

GT2D1_MOUSE
θ value	0 (rank : 2)	NC score	0.990907 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

GTF2I_HUMAN
θ value	2.71407e-105 (rank : 3)	NC score	0.865123 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

GTF2I_MOUSE
θ value	3.91911e-104 (rank : 4)	NC score	0.879435 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

MAGI2_HUMAN
θ value	0.62314 (rank : 5)	NC score	0.018485 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	373	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

ACD_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.051239 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

PABP2_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.026676 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	212	Shared Neighborhood Hits	2
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

NCA11_MOUSE
θ value	1.06291 (rank : 8)	NC score	0.015184 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	661	Shared Neighborhood Hits	7
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

ENAH_MOUSE
θ value	1.38821 (rank : 9)	NC score	0.017704 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	919	Shared Neighborhood Hits	10
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

PEG3_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.006661 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	1101	Shared Neighborhood Hits	6
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

TITIN_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.010586 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	2923	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SAPS1_MOUSE
θ value	1.81305 (rank : 12)	NC score	0.018533 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

BCAS1_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.025853 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	133	Shared Neighborhood Hits	2
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

SMOO_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.018060 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	391	Shared Neighborhood Hits	9
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CASP_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.007817 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	1152	Shared Neighborhood Hits	6
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CIR1A_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.023187 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R2N2, Q62306, Q69Z48, Q6NVG9, Q8VEL5	Gene names	Cirh1a, Kiaa1988, Tex292
Domain Architecture	No domain graphic available
Description	Cirhin (Testis-expressed gene 292 protein).

CUTL1_MOUSE
θ value	3.0926 (rank : 17)	NC score	0.009132 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	1620	Shared Neighborhood Hits	11
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

GRB10_HUMAN
θ value	3.0926 (rank : 18)	NC score	0.034283 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	147	Shared Neighborhood Hits	6
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

GRB10_MOUSE
θ value	3.0926 (rank : 19)	NC score	0.034593 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

K0329_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.050137 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

MGR1_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.008619 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

NACAM_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.015884 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	1866	Shared Neighborhood Hits	20
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

AF10_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.012339 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	182	Shared Neighborhood Hits	5
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AR13B_MOUSE
θ value	4.03905 (rank : 24)	NC score	0.009009 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	245	Shared Neighborhood Hits	2
SwissProt Accessions	Q640N2	Gene names	Arl13b, Arl2l1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

CRSP7_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.023812 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	247	Shared Neighborhood Hits	5
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

ELK1_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.010241 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

ZEP2_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.004727 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	964	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

APBA2_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.012605 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

C2TA_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.013767 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

GRB7_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.022144 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

PK3CG_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.008196 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

WASIP_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.015029 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	392	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

CCAR1_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.010883 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	414	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

GRB14_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.020243 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

K1849_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.011853 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	220	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MEF2B_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.012291 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

PRRT3_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.013241 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	998	Shared Neighborhood Hits	15
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TAD3L_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.020066 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	189	Shared Neighborhood Hits	4
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

TAD3L_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.020193 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

CIR1A_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.017894 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q969X6, Q8NCD9, Q8TF14, Q96SP0, Q96SR9, Q96SZ9, Q96T13, Q9BWK6	Gene names	CIRH1A, KIAA1988
Domain Architecture
Description	Cirhin.

CO8A1_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.003900 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	251	Shared Neighborhood Hits	4
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

HUNK_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.000140 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	874	Shared Neighborhood Hits	4
SwissProt Accessions	O88866	Gene names	Hunk, Makv
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V).

MAGAB_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.004398 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P43364, Q5ETU4, Q6ZRZ5	Gene names	MAGEA11, MAGE11
Domain Architecture
Description	Melanoma-associated antigen 11 (MAGE-11 antigen).

REXO1_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.010310 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

TGFB4_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.008227 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	Q64280	Gene names	Ebaf, Lefty, Lefty1, Stra3, Tgfb4
Domain Architecture
Description	Transforming growth factor beta-4 precursor (TGF-beta-4) (Lefty protein) (Lefty-1 protein) (STRA3 protein).

WNK2_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.001015 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	1407	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

Hits sorted by NC score

GT2D1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UHL9, O95444, Q75MX7, Q86UM3, Q8WVC4, Q9UHK8, Q9UI91	Gene names	GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Muscle TFII-I repeat domain-containing protein 1) (General transcription factor III) (Slow- muscle-fiber enhancer-binding protein) (USE B1-binding protein) (MusTRD1/BEN) (Williams-Beuren syndrome chromosome region 11 protein).

GT2D1_MOUSE
NC score	0.990907 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JI57, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7	Gene names	Gtf2ird1, Ben
Domain Architecture
Description	General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (Binding factor for early enhancer).

GTF2I_MOUSE
NC score	0.879435 (rank : 3)	θ value	3.91911e-104 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ESZ8, O54700, O55030, O55031, Q8VHD1, Q8VHD2, Q8VHD3, Q8VHD4, Q9CSB5, Q9D9K9	Gene names	Gtf2i, Bap135, Diws1t
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135).

GTF2I_HUMAN
NC score	0.865123 (rank : 4)	θ value	2.71407e-105 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	P78347, O14743, O15359, O43546, O43588, O43589, Q9BSZ4	Gene names	GTF2I, BAP135, WBSCR6
Domain Architecture
Description	General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BTK-associated protein 135) (BAP-135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosome region 6 protein).

ACD_HUMAN
NC score	0.051239 (rank : 5)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

K0329_HUMAN
NC score	0.050137 (rank : 6)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	O15040, Q9UEG6	Gene names	KIAA0329, KIAA0297
Domain Architecture
Description	Protein KIAA0329/KIAA0297.

GRB10_MOUSE
NC score	0.034593 (rank : 7)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q60760, O35352, Q7TSA4, Q8BSH4, Q8BSS5, Q91WC5	Gene names	Grb10
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein).

GRB10_HUMAN
NC score	0.034283 (rank : 8)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	147	Shared Neighborhood Hits	6
SwissProt Accessions	Q13322, O00427, O00701, O75222, Q92606, Q92907, Q92948	Gene names	GRB10, GRBIR, KIAA0207
Domain Architecture
Description	Growth factor receptor-bound protein 10 (GRB10 adaptor protein) (Insulin receptor-binding protein GRB-IR).

PABP2_HUMAN
NC score	0.026676 (rank : 9)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	212	Shared Neighborhood Hits	2
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

BCAS1_HUMAN
NC score	0.025853 (rank : 10)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	133	Shared Neighborhood Hits	2
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

CRSP7_HUMAN
NC score	0.023812 (rank : 11)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	247	Shared Neighborhood Hits	5
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

CIR1A_MOUSE
NC score	0.023187 (rank : 12)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	155	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R2N2, Q62306, Q69Z48, Q6NVG9, Q8VEL5	Gene names	Cirh1a, Kiaa1988, Tex292
Domain Architecture	No domain graphic available
Description	Cirhin (Testis-expressed gene 292 protein).

GRB7_HUMAN
NC score	0.022144 (rank : 13)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	Q14451, Q92568, Q96DF9	Gene names	GRB7
Domain Architecture
Description	Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7) (B47).

GRB14_HUMAN
NC score	0.020243 (rank : 14)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	137	Shared Neighborhood Hits	5
SwissProt Accessions	Q14449, Q7Z6I1	Gene names	GRB14
Domain Architecture
Description	Growth factor receptor-bound protein 14 (GRB14 adapter protein).

TAD3L_MOUSE
NC score	0.020193 (rank : 15)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R0L9, Q8CIH4, Q8K289, Q8R5E3, Q9CTJ0	Gene names	Tada3l, Ada3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (mADA3).

TAD3L_HUMAN
NC score	0.020066 (rank : 16)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	189	Shared Neighborhood Hits	4
SwissProt Accessions	O75528, Q9UFS2	Gene names	TADA3L, ADA3
Domain Architecture	No domain graphic available
Description	Transcriptional adapter 3-like (ADA3-like protein) (ADA3 homolog) (hADA3).

SAPS1_MOUSE
NC score	0.018533 (rank : 17)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	144	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

MAGI2_HUMAN
NC score	0.018485 (rank : 18)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	373	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

SMOO_HUMAN
NC score	0.018060 (rank : 19)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	391	Shared Neighborhood Hits	9
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CIR1A_HUMAN
NC score	0.017894 (rank : 20)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	158	Shared Neighborhood Hits	3
SwissProt Accessions	Q969X6, Q8NCD9, Q8TF14, Q96SP0, Q96SR9, Q96SZ9, Q96T13, Q9BWK6	Gene names	CIRH1A, KIAA1988
Domain Architecture
Description	Cirhin.

ENAH_MOUSE
NC score	0.017704 (rank : 21)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	919	Shared Neighborhood Hits	10
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

NACAM_MOUSE
NC score	0.015884 (rank : 22)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	1866	Shared Neighborhood Hits	20
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCA11_MOUSE
NC score	0.015184 (rank : 23)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	661	Shared Neighborhood Hits	7
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

WASIP_MOUSE
NC score	0.015029 (rank : 24)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	392	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

C2TA_HUMAN
NC score	0.013767 (rank : 25)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

PRRT3_HUMAN
NC score	0.013241 (rank : 26)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	998	Shared Neighborhood Hits	15
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

APBA2_MOUSE
NC score	0.012605 (rank : 27)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

AF10_MOUSE
NC score	0.012339 (rank : 28)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	182	Shared Neighborhood Hits	5
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

MEF2B_MOUSE
NC score	0.012291 (rank : 29)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

K1849_HUMAN
NC score	0.011853 (rank : 30)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	220	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JH8, Q75LH3, Q9BSP5, Q9H0M6, Q9NW43, Q9NWC4	Gene names	KIAA1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

CCAR1_MOUSE
NC score	0.010883 (rank : 31)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	414	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

TITIN_HUMAN
NC score	0.010586 (rank : 32)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	2923	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

REXO1_HUMAN
NC score	0.010310 (rank : 33)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	242	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

ELK1_HUMAN
NC score	0.010241 (rank : 34)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

CUTL1_MOUSE
NC score	0.009132 (rank : 35)	θ value	3.0926 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	1620	Shared Neighborhood Hits	11
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

AR13B_MOUSE
NC score	0.009009 (rank : 36)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	245	Shared Neighborhood Hits	2
SwissProt Accessions	Q640N2	Gene names	Arl13b, Arl2l1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

MGR1_HUMAN
NC score	0.008619 (rank : 37)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

TGFB4_MOUSE
NC score	0.008227 (rank : 38)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	Q64280	Gene names	Ebaf, Lefty, Lefty1, Stra3, Tgfb4
Domain Architecture
Description	Transforming growth factor beta-4 precursor (TGF-beta-4) (Lefty protein) (Lefty-1 protein) (STRA3 protein).

PK3CG_MOUSE
NC score	0.008196 (rank : 39)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

CASP_MOUSE
NC score	0.007817 (rank : 40)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	1152	Shared Neighborhood Hits	6
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

PEG3_MOUSE
NC score	0.006661 (rank : 41)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	1101	Shared Neighborhood Hits	6
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

ZEP2_MOUSE
NC score	0.004727 (rank : 42)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	964	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

MAGAB_HUMAN
NC score	0.004398 (rank : 43)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	P43364, Q5ETU4, Q6ZRZ5	Gene names	MAGEA11, MAGE11
Domain Architecture
Description	Melanoma-associated antigen 11 (MAGE-11 antigen).

CO8A1_MOUSE
NC score	0.003900 (rank : 44)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	251	Shared Neighborhood Hits	4
SwissProt Accessions	Q00780, Q9D2V4	Gene names	Col8a1
Domain Architecture
Description	Collagen alpha-1(VIII) chain precursor.

WNK2_HUMAN
NC score	0.001015 (rank : 45)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	1407	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

HUNK_MOUSE
NC score	0.000140 (rank : 46)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	874	Shared Neighborhood Hits	4
SwissProt Accessions	O88866	Gene names	Hunk, Makv
Domain Architecture
Description	Hormonally up-regulated neu tumor-associated kinase (EC 2.7.11.1) (Serine/threonine-protein kinase MAK-V).