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Network neighborhood for query Sequence : PKP4_HUMAN

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PKP4_HUMAN
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CTND2_HUMAN
θ value	0 (rank : 1)	NC score	0.951556 (rank : 4)
Query Neighborhood Hits	107	Target Neighborhood Hits	333	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

CTND2_MOUSE
θ value	0 (rank : 2)	NC score	0.964321 (rank : 3)
Query Neighborhood Hits	107	Target Neighborhood Hits	227	Shared Neighborhood Hits	45
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

PKP4_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	107	Target Neighborhood Hits	107	Shared Neighborhood Hits	107
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PKP4_MOUSE
θ value	0 (rank : 4)	NC score	0.993729 (rank : 2)
Query Neighborhood Hits	107	Target Neighborhood Hits	129	Shared Neighborhood Hits	75
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

ARVC_HUMAN
θ value	2.97994e-128 (rank : 5)	NC score	0.945767 (rank : 6)
Query Neighborhood Hits	107	Target Neighborhood Hits	95	Shared Neighborhood Hits	36
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ARVC_MOUSE
θ value	3.64273e-126 (rank : 6)	NC score	0.947461 (rank : 5)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

CTND1_MOUSE
θ value	1.58377e-121 (rank : 7)	NC score	0.942942 (rank : 7)
Query Neighborhood Hits	107	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_HUMAN
θ value	1.93603e-119 (rank : 8)	NC score	0.940777 (rank : 8)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

PKP1_MOUSE
θ value	3.34864e-71 (rank : 9)	NC score	0.902917 (rank : 10)
Query Neighborhood Hits	107	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP1_HUMAN
θ value	9.11921e-69 (rank : 10)	NC score	0.901647 (rank : 11)
Query Neighborhood Hits	107	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP2_HUMAN
θ value	7.71989e-68 (rank : 11)	NC score	0.909864 (rank : 9)
Query Neighborhood Hits	107	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

PKP3_HUMAN
θ value	1.50663e-63 (rank : 12)	NC score	0.898959 (rank : 12)
Query Neighborhood Hits	107	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
θ value	1.50663e-63 (rank : 13)	NC score	0.898165 (rank : 13)
Query Neighborhood Hits	107	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

APC_MOUSE
θ value	4.1701e-05 (rank : 14)	NC score	0.236845 (rank : 18)
Query Neighborhood Hits	107	Target Neighborhood Hits	441	Shared Neighborhood Hits	38
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
θ value	5.44631e-05 (rank : 15)	NC score	0.231467 (rank : 19)
Query Neighborhood Hits	107	Target Neighborhood Hits	603	Shared Neighborhood Hits	41
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

IMA7_MOUSE
θ value	0.000121331 (rank : 16)	NC score	0.187907 (rank : 21)
Query Neighborhood Hits	107	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA7_HUMAN
θ value	0.00035302 (rank : 17)	NC score	0.183361 (rank : 22)
Query Neighborhood Hits	107	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA2_HUMAN
θ value	0.00175202 (rank : 18)	NC score	0.168865 (rank : 26)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
θ value	0.00175202 (rank : 19)	NC score	0.169775 (rank : 25)
Query Neighborhood Hits	107	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

ARMC4_HUMAN
θ value	0.00298849 (rank : 20)	NC score	0.365895 (rank : 14)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CTNB1_HUMAN
θ value	0.00509761 (rank : 21)	NC score	0.272055 (rank : 16)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	30
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	0.00509761 (rank : 22)	NC score	0.272120 (rank : 15)
Query Neighborhood Hits	107	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

IMA4_HUMAN
θ value	0.00509761 (rank : 23)	NC score	0.161982 (rank : 27)
Query Neighborhood Hits	107	Target Neighborhood Hits	59	Shared Neighborhood Hits	24
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
θ value	0.00509761 (rank : 24)	NC score	0.161978 (rank : 28)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

PLAK_HUMAN
θ value	0.00665767 (rank : 25)	NC score	0.204873 (rank : 20)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

IMA5_HUMAN
θ value	0.0148317 (rank : 26)	NC score	0.175243 (rank : 23)
Query Neighborhood Hits	107	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

HIF1N_MOUSE
θ value	0.0563607 (rank : 27)	NC score	0.054908 (rank : 40)
Query Neighborhood Hits	107	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLR9, Q3U3G4	Gene names	Hif1an
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha inhibitor (EC 1.14.11.16) (Hypoxia- inducible factor asparagine hydroxylase).

NACAM_MOUSE
θ value	0.0736092 (rank : 28)	NC score	0.050494 (rank : 44)
Query Neighborhood Hits	107	Target Neighborhood Hits	1866	Shared Neighborhood Hits	53
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

RPTN_MOUSE
θ value	0.0736092 (rank : 29)	NC score	0.016919 (rank : 77)
Query Neighborhood Hits	107	Target Neighborhood Hits	650	Shared Neighborhood Hits	12
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

IMA1_HUMAN
θ value	0.0961366 (rank : 30)	NC score	0.147843 (rank : 31)
Query Neighborhood Hits	107	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
θ value	0.0961366 (rank : 31)	NC score	0.147584 (rank : 32)
Query Neighborhood Hits	107	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

IMA3_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.154532 (rank : 30)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA3_MOUSE
θ value	0.125558 (rank : 33)	NC score	0.154663 (rank : 29)
Query Neighborhood Hits	107	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

PLAK_MOUSE
θ value	0.163984 (rank : 34)	NC score	0.241204 (rank : 17)
Query Neighborhood Hits	107	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

SPTN5_HUMAN
θ value	0.163984 (rank : 35)	NC score	0.014882 (rank : 84)
Query Neighborhood Hits	107	Target Neighborhood Hits	674	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

MUC7_HUMAN
θ value	0.21417 (rank : 36)	NC score	0.050707 (rank : 43)
Query Neighborhood Hits	107	Target Neighborhood Hits	538	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

AKAP2_MOUSE
θ value	0.279714 (rank : 37)	NC score	0.035747 (rank : 52)
Query Neighborhood Hits	107	Target Neighborhood Hits	385	Shared Neighborhood Hits	16
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CCD27_MOUSE
θ value	0.279714 (rank : 38)	NC score	0.023457 (rank : 63)
Query Neighborhood Hits	107	Target Neighborhood Hits	461	Shared Neighborhood Hits	6
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

EPCR_HUMAN
θ value	0.279714 (rank : 39)	NC score	0.049014 (rank : 46)
Query Neighborhood Hits	107	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNN8, Q14218, Q6IB56, Q96CB3, Q9ULX1	Gene names	PROCR, EPCR
Domain Architecture
Description	Endothelial protein C receptor precursor (Endothelial cell protein C receptor) (Activated protein C receptor) (APC receptor) (CD201 antigen).

PRC1_HUMAN
θ value	0.279714 (rank : 40)	NC score	0.032505 (rank : 56)
Query Neighborhood Hits	107	Target Neighborhood Hits	328	Shared Neighborhood Hits	6
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

SON_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.022977 (rank : 64)
Query Neighborhood Hits	107	Target Neighborhood Hits	1568	Shared Neighborhood Hits	39
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NFRKB_MOUSE
θ value	0.365318 (rank : 42)	NC score	0.040775 (rank : 51)
Query Neighborhood Hits	107	Target Neighborhood Hits	393	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NP1L3_MOUSE
θ value	0.365318 (rank : 43)	NC score	0.020168 (rank : 71)
Query Neighborhood Hits	107	Target Neighborhood Hits	233	Shared Neighborhood Hits	7
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

GAB1_MOUSE
θ value	0.47712 (rank : 44)	NC score	0.032841 (rank : 55)
Query Neighborhood Hits	107	Target Neighborhood Hits	233	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

HEAT3_MOUSE
θ value	0.62314 (rank : 45)	NC score	0.079105 (rank : 33)
Query Neighborhood Hits	107	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BQM4, Q8C731	Gene names	Heatr3
Domain Architecture
Description	HEAT repeat-containing protein 3.

WT1_HUMAN
θ value	0.62314 (rank : 46)	NC score	0.001889 (rank : 105)
Query Neighborhood Hits	107	Target Neighborhood Hits	720	Shared Neighborhood Hits	7
SwissProt Accessions	P19544, Q15881, Q16256, Q16575, Q8IYZ5	Gene names	WT1
Domain Architecture
Description	Wilms' tumor protein (WT33).

AFF4_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.027494 (rank : 59)
Query Neighborhood Hits	107	Target Neighborhood Hits	611	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ANK2_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.012463 (rank : 87)
Query Neighborhood Hits	107	Target Neighborhood Hits	1615	Shared Neighborhood Hits	41
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MTMR7_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.016259 (rank : 79)
Query Neighborhood Hits	107	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

PCDA9_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.002619 (rank : 104)
Query Neighborhood Hits	107	Target Neighborhood Hits	203	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5H5, O15053	Gene names	PCDHA9, KIAA0345
Domain Architecture
Description	Protocadherin alpha 9 precursor (PCDH-alpha9).

TARA_HUMAN
θ value	0.813845 (rank : 51)	NC score	0.022911 (rank : 65)
Query Neighborhood Hits	107	Target Neighborhood Hits	1626	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SRRM2_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.041629 (rank : 48)
Query Neighborhood Hits	107	Target Neighborhood Hits	1296	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DAG1_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.034721 (rank : 54)
Query Neighborhood Hits	107	Target Neighborhood Hits	104	Shared Neighborhood Hits	12
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

GDS1_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.174868 (rank : 24)
Query Neighborhood Hits	107	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

MLL3_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.020568 (rank : 70)
Query Neighborhood Hits	107	Target Neighborhood Hits	1399	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NCOR1_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.024462 (rank : 61)
Query Neighborhood Hits	107	Target Neighborhood Hits	521	Shared Neighborhood Hits	19
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

PDXL2_MOUSE
θ value	1.38821 (rank : 57)	NC score	0.031322 (rank : 57)
Query Neighborhood Hits	107	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

CDKL5_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.004602 (rank : 97)
Query Neighborhood Hits	107	Target Neighborhood Hits	967	Shared Neighborhood Hits	17
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

COE1_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.020905 (rank : 67)
Query Neighborhood Hits	107	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UH73, Q8IW11	Gene names	EBF1, COE1, EBF
Domain Architecture
Description	Transcription factor COE1 (OE-1) (O/E-1) (Early B-cell factor).

COE1_MOUSE
θ value	1.81305 (rank : 60)	NC score	0.020905 (rank : 68)
Query Neighborhood Hits	107	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q07802	Gene names	Ebf1, Coe1, Ebf
Domain Architecture
Description	Transcription factor COE1 (OE-1) (O/E-1) (Early B-cell factor).

EGR1_MOUSE
θ value	1.81305 (rank : 61)	NC score	0.001187 (rank : 106)
Query Neighborhood Hits	107	Target Neighborhood Hits	816	Shared Neighborhood Hits	13
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

MUC2_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.024092 (rank : 62)
Query Neighborhood Hits	107	Target Neighborhood Hits	906	Shared Neighborhood Hits	33
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TRPS1_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.010309 (rank : 89)
Query Neighborhood Hits	107	Target Neighborhood Hits	609	Shared Neighborhood Hits	7
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

BMP2K_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.003406 (rank : 99)
Query Neighborhood Hits	107	Target Neighborhood Hits	874	Shared Neighborhood Hits	12
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

DAG1_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.028692 (rank : 58)
Query Neighborhood Hits	107	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q62165, Q61094, Q61141, Q61497	Gene names	Dag1, Dag-1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

DOT1L_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.041385 (rank : 50)
Query Neighborhood Hits	107	Target Neighborhood Hits	660	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

GAB1_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.022444 (rank : 66)
Query Neighborhood Hits	107	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

HIF1N_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.035363 (rank : 53)
Query Neighborhood Hits	107	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWT6, Q969Q7, Q9NPV5	Gene names	HIF1AN, FIH1
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha inhibitor (EC 1.14.11.16) (Hypoxia- inducible factor asparagine hydroxylase) (Factor inhibiting HIF-1) (FIH-1).

MAVS_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.045116 (rank : 47)
Query Neighborhood Hits	107	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

RIMB1_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.016671 (rank : 78)
Query Neighborhood Hits	107	Target Neighborhood Hits	1376	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ZBTB3_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.003374 (rank : 100)
Query Neighborhood Hits	107	Target Neighborhood Hits	910	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

MUC13_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.015544 (rank : 81)
Query Neighborhood Hits	107	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MYO15_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.004936 (rank : 94)
Query Neighborhood Hits	107	Target Neighborhood Hits	671	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RTDR1_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.058602 (rank : 36)
Query Neighborhood Hits	107	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

SMN_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.041402 (rank : 49)
Query Neighborhood Hits	107	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

TLN2_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.011188 (rank : 88)
Query Neighborhood Hits	107	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

WDR79_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.009563 (rank : 90)
Query Neighborhood Hits	107	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

ASPP2_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.006168 (rank : 92)
Query Neighborhood Hits	107	Target Neighborhood Hits	1156	Shared Neighborhood Hits	23
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CNOT3_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.017739 (rank : 76)
Query Neighborhood Hits	107	Target Neighborhood Hits	504	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

K1718_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.019856 (rank : 72)
Query Neighborhood Hits	107	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

MEGF9_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.005518 (rank : 93)
Query Neighborhood Hits	107	Target Neighborhood Hits	557	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SET1A_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.015677 (rank : 80)
Query Neighborhood Hits	107	Target Neighborhood Hits	690	Shared Neighborhood Hits	25
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TRI66_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.015203 (rank : 83)
Query Neighborhood Hits	107	Target Neighborhood Hits	491	Shared Neighborhood Hits	14
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

WT1_MOUSE
θ value	4.03905 (rank : 84)	NC score	-0.000023 (rank : 110)
Query Neighborhood Hits	107	Target Neighborhood Hits	723	Shared Neighborhood Hits	5
SwissProt Accessions	P22561	Gene names	Wt1, Wt-1
Domain Architecture
Description	Wilms' tumor protein homolog.

ATN1_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.058592 (rank : 37)
Query Neighborhood Hits	107	Target Neighborhood Hits	676	Shared Neighborhood Hits	27
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAP1_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.020699 (rank : 69)
Query Neighborhood Hits	107	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

P66A_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.015232 (rank : 82)
Query Neighborhood Hits	107	Target Neighborhood Hits	111	Shared Neighborhood Hits	11
SwissProt Accessions	Q86YP4, Q7L3J2, Q96F28, Q9NPU2, Q9NXS1	Gene names	GATAD2A
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A).

PER3_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.025365 (rank : 60)
Query Neighborhood Hits	107	Target Neighborhood Hits	479	Shared Neighborhood Hits	27
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PTPRZ_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.002681 (rank : 103)
Query Neighborhood Hits	107	Target Neighborhood Hits	255	Shared Neighborhood Hits	8
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

SPEG_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.000513 (rank : 109)
Query Neighborhood Hits	107	Target Neighborhood Hits	1762	Shared Neighborhood Hits	28
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TAB3_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.019268 (rank : 74)
Query Neighborhood Hits	107	Target Neighborhood Hits	168	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TAB3_MOUSE
θ value	5.27518 (rank : 92)	NC score	0.019443 (rank : 73)
Query Neighborhood Hits	107	Target Neighborhood Hits	273	Shared Neighborhood Hits	14
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

WHRN_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.004411 (rank : 98)
Query Neighborhood Hits	107	Target Neighborhood Hits	412	Shared Neighborhood Hits	7
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

CNOT3_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.018819 (rank : 75)
Query Neighborhood Hits	107	Target Neighborhood Hits	425	Shared Neighborhood Hits	17
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

GP125_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.003047 (rank : 102)
Query Neighborhood Hits	107	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

HEAT3_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.051945 (rank : 42)
Query Neighborhood Hits	107	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4Q2, Q8N525, Q8WV56, Q96CC9, Q9NWN7	Gene names	HEATR3
Domain Architecture
Description	HEAT repeat-containing protein 3.

KCNN1_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.004686 (rank : 96)
Query Neighborhood Hits	107	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

MUCDL_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.013969 (rank : 85)
Query Neighborhood Hits	107	Target Neighborhood Hits	461	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NFH_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.003242 (rank : 101)
Query Neighborhood Hits	107	Target Neighborhood Hits	1242	Shared Neighborhood Hits	20
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

P66A_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.012601 (rank : 86)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHY6, Q8BTQ2, Q8VEC9	Gene names	Gatad2a
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (GATA zinc finger domain- containing protein 2A).

AATK_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.000537 (rank : 108)
Query Neighborhood Hits	107	Target Neighborhood Hits	1243	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ABL2_HUMAN
θ value	8.99809 (rank : 102)	NC score	-0.001882 (rank : 111)
Query Neighborhood Hits	107	Target Neighborhood Hits	1045	Shared Neighborhood Hits	15
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ANK3_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.004935 (rank : 95)
Query Neighborhood Hits	107	Target Neighborhood Hits	853	Shared Neighborhood Hits	21
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

FOXE1_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.001026 (rank : 107)
Query Neighborhood Hits	107	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O00358, O75765	Gene names	FOXE1, FKHL15, TITF2, TTF2
Domain Architecture
Description	Forkhead box protein E1 (Thyroid transcription factor 2) (TTF-2) (Forkhead-related protein FKHL15).

MTMR7_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.008830 (rank : 91)
Query Neighborhood Hits	107	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

SRRM2_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.049027 (rank : 45)
Query Neighborhood Hits	107	Target Neighborhood Hits	1470	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ZAP70_HUMAN
θ value	8.99809 (rank : 107)	NC score	-0.002602 (rank : 112)
Query Neighborhood Hits	107	Target Neighborhood Hits	893	Shared Neighborhood Hits	7
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

CK024_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.055352 (rank : 39)
Query Neighborhood Hits	107	Target Neighborhood Hits	408	Shared Neighborhood Hits	21
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

MUC13_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.057270 (rank : 38)
Query Neighborhood Hits	107	Target Neighborhood Hits	447	Shared Neighborhood Hits	21
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PARM1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.054049 (rank : 41)
Query Neighborhood Hits	107	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

SPAG6_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.068854 (rank : 34)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

SPAG6_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.061694 (rank : 35)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

Hits sorted by NC score

PKP4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	107	Target Neighborhood Hits	107	Shared Neighborhood Hits	107
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PKP4_MOUSE
NC score	0.993729 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	107	Target Neighborhood Hits	129	Shared Neighborhood Hits	75
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

CTND2_MOUSE
NC score	0.964321 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	107	Target Neighborhood Hits	227	Shared Neighborhood Hits	45
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CTND2_HUMAN
NC score	0.951556 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	107	Target Neighborhood Hits	333	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

ARVC_MOUSE
NC score	0.947461 (rank : 5)	θ value	3.64273e-126 (rank : 6)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

ARVC_HUMAN
NC score	0.945767 (rank : 6)	θ value	2.97994e-128 (rank : 5)
Query Neighborhood Hits	107	Target Neighborhood Hits	95	Shared Neighborhood Hits	36
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

CTND1_MOUSE
NC score	0.942942 (rank : 7)	θ value	1.58377e-121 (rank : 7)
Query Neighborhood Hits	107	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_HUMAN
NC score	0.940777 (rank : 8)	θ value	1.93603e-119 (rank : 8)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

PKP2_HUMAN
NC score	0.909864 (rank : 9)	θ value	7.71989e-68 (rank : 11)
Query Neighborhood Hits	107	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

PKP1_MOUSE
NC score	0.902917 (rank : 10)	θ value	3.34864e-71 (rank : 9)
Query Neighborhood Hits	107	Target Neighborhood Hits	37	Shared Neighborhood Hits	22
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP1_HUMAN
NC score	0.901647 (rank : 11)	θ value	9.11921e-69 (rank : 10)
Query Neighborhood Hits	107	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP3_HUMAN
NC score	0.898959 (rank : 12)	θ value	1.50663e-63 (rank : 12)
Query Neighborhood Hits	107	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
NC score	0.898165 (rank : 13)	θ value	1.50663e-63 (rank : 13)
Query Neighborhood Hits	107	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

ARMC4_HUMAN
NC score	0.365895 (rank : 14)	θ value	0.00298849 (rank : 20)
Query Neighborhood Hits	107	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CTNB1_MOUSE
NC score	0.272120 (rank : 15)	θ value	0.00509761 (rank : 22)
Query Neighborhood Hits	107	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.272055 (rank : 16)	θ value	0.00509761 (rank : 21)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	30
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
NC score	0.241204 (rank : 17)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	107	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

APC_MOUSE
NC score	0.236845 (rank : 18)	θ value	4.1701e-05 (rank : 14)
Query Neighborhood Hits	107	Target Neighborhood Hits	441	Shared Neighborhood Hits	38
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
NC score	0.231467 (rank : 19)	θ value	5.44631e-05 (rank : 15)
Query Neighborhood Hits	107	Target Neighborhood Hits	603	Shared Neighborhood Hits	41
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PLAK_HUMAN
NC score	0.204873 (rank : 20)	θ value	0.00665767 (rank : 25)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

IMA7_MOUSE
NC score	0.187907 (rank : 21)	θ value	0.000121331 (rank : 16)
Query Neighborhood Hits	107	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA7_HUMAN
NC score	0.183361 (rank : 22)	θ value	0.00035302 (rank : 17)
Query Neighborhood Hits	107	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA5_HUMAN
NC score	0.175243 (rank : 23)	θ value	0.0148317 (rank : 26)
Query Neighborhood Hits	107	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

GDS1_HUMAN
NC score	0.174868 (rank : 24)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	107	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

IMA2_MOUSE
NC score	0.169775 (rank : 25)	θ value	0.00175202 (rank : 19)
Query Neighborhood Hits	107	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA2_HUMAN
NC score	0.168865 (rank : 26)	θ value	0.00175202 (rank : 18)
Query Neighborhood Hits	107	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA4_HUMAN
NC score	0.161982 (rank : 27)	θ value	0.00509761 (rank : 23)
Query Neighborhood Hits	107	Target Neighborhood Hits	59	Shared Neighborhood Hits	24
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
NC score	0.161978 (rank : 28)	θ value	0.00509761 (rank : 24)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA3_MOUSE
NC score	0.154663 (rank : 29)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	107	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA3_HUMAN
NC score	0.154532 (rank : 30)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA1_HUMAN
NC score	0.147843 (rank : 31)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	107	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
NC score	0.147584 (rank : 32)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	107	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

HEAT3_MOUSE
NC score	0.079105 (rank : 33)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	107	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BQM4, Q8C731	Gene names	Heatr3
Domain Architecture
Description	HEAT repeat-containing protein 3.

SPAG6_HUMAN
NC score	0.068854 (rank : 34)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

SPAG6_MOUSE
NC score	0.061694 (rank : 35)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

RTDR1_HUMAN
NC score	0.058602 (rank : 36)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	107	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

ATN1_HUMAN
NC score	0.058592 (rank : 37)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	107	Target Neighborhood Hits	676	Shared Neighborhood Hits	27
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MUC13_MOUSE
NC score	0.057270 (rank : 38)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	107	Target Neighborhood Hits	447	Shared Neighborhood Hits	21
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

CK024_HUMAN
NC score	0.055352 (rank : 39)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	107	Target Neighborhood Hits	408	Shared Neighborhood Hits	21
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

HIF1N_MOUSE
NC score	0.054908 (rank : 40)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	107	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLR9, Q3U3G4	Gene names	Hif1an
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha inhibitor (EC 1.14.11.16) (Hypoxia- inducible factor asparagine hydroxylase).

PARM1_MOUSE
NC score	0.054049 (rank : 41)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	107	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

HEAT3_HUMAN
NC score	0.051945 (rank : 42)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	107	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4Q2, Q8N525, Q8WV56, Q96CC9, Q9NWN7	Gene names	HEATR3
Domain Architecture
Description	HEAT repeat-containing protein 3.

MUC7_HUMAN
NC score	0.050707 (rank : 43)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	107	Target Neighborhood Hits	538	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NACAM_MOUSE
NC score	0.050494 (rank : 44)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	107	Target Neighborhood Hits	1866	Shared Neighborhood Hits	53
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SRRM2_MOUSE
NC score	0.049027 (rank : 45)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	107	Target Neighborhood Hits	1470	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

EPCR_HUMAN
NC score	0.049014 (rank : 46)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	107	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNN8, Q14218, Q6IB56, Q96CB3, Q9ULX1	Gene names	PROCR, EPCR
Domain Architecture
Description	Endothelial protein C receptor precursor (Endothelial cell protein C receptor) (Activated protein C receptor) (APC receptor) (CD201 antigen).

MAVS_HUMAN
NC score	0.045116 (rank : 47)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	107	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

SRRM2_HUMAN
NC score	0.041629 (rank : 48)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	107	Target Neighborhood Hits	1296	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SMN_HUMAN
NC score	0.041402 (rank : 49)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	107	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

DOT1L_HUMAN
NC score	0.041385 (rank : 50)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	107	Target Neighborhood Hits	660	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

NFRKB_MOUSE
NC score	0.040775 (rank : 51)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	107	Target Neighborhood Hits	393	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

AKAP2_MOUSE
NC score	0.035747 (rank : 52)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	107	Target Neighborhood Hits	385	Shared Neighborhood Hits	16
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

HIF1N_HUMAN
NC score	0.035363 (rank : 53)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	107	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWT6, Q969Q7, Q9NPV5	Gene names	HIF1AN, FIH1
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha inhibitor (EC 1.14.11.16) (Hypoxia- inducible factor asparagine hydroxylase) (Factor inhibiting HIF-1) (FIH-1).

DAG1_HUMAN
NC score	0.034721 (rank : 54)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	107	Target Neighborhood Hits	104	Shared Neighborhood Hits	12
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

GAB1_MOUSE
NC score	0.032841 (rank : 55)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	107	Target Neighborhood Hits	233	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PRC1_HUMAN
NC score	0.032505 (rank : 56)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	107	Target Neighborhood Hits	328	Shared Neighborhood Hits	6
SwissProt Accessions	O43663, Q9BSB6	Gene names	PRC1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

PDXL2_MOUSE
NC score	0.031322 (rank : 57)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	107	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

DAG1_MOUSE
NC score	0.028692 (rank : 58)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	107	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q62165, Q61094, Q61141, Q61497	Gene names	Dag1, Dag-1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

AFF4_HUMAN
NC score	0.027494 (rank : 59)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	107	Target Neighborhood Hits	611	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

PER3_HUMAN
NC score	0.025365 (rank : 60)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	107	Target Neighborhood Hits	479	Shared Neighborhood Hits	27
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

NCOR1_MOUSE
NC score	0.024462 (rank : 61)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	107	Target Neighborhood Hits	521	Shared Neighborhood Hits	19
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

MUC2_HUMAN
NC score	0.024092 (rank : 62)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	107	Target Neighborhood Hits	906	Shared Neighborhood Hits	33
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CCD27_MOUSE
NC score	0.023457 (rank : 63)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	107	Target Neighborhood Hits	461	Shared Neighborhood Hits	6
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

SON_HUMAN
NC score	0.022977 (rank : 64)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	107	Target Neighborhood Hits	1568	Shared Neighborhood Hits	39
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TARA_HUMAN
NC score	0.022911 (rank : 65)	θ value	0.813845 (rank : 51)
Query Neighborhood Hits	107	Target Neighborhood Hits	1626	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

GAB1_HUMAN
NC score	0.022444 (rank : 66)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	107	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

COE1_HUMAN
NC score	0.020905 (rank : 67)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	107	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UH73, Q8IW11	Gene names	EBF1, COE1, EBF
Domain Architecture
Description	Transcription factor COE1 (OE-1) (O/E-1) (Early B-cell factor).

COE1_MOUSE
NC score	0.020905 (rank : 68)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	107	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q07802	Gene names	Ebf1, Coe1, Ebf
Domain Architecture
Description	Transcription factor COE1 (OE-1) (O/E-1) (Early B-cell factor).

BAP1_HUMAN
NC score	0.020699 (rank : 69)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	107	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

MLL3_MOUSE
NC score	0.020568 (rank : 70)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	107	Target Neighborhood Hits	1399	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NP1L3_MOUSE
NC score	0.020168 (rank : 71)	θ value	0.365318 (rank : 43)
Query Neighborhood Hits	107	Target Neighborhood Hits	233	Shared Neighborhood Hits	7
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

K1718_HUMAN
NC score	0.019856 (rank : 72)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	107	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

TAB3_MOUSE
NC score	0.019443 (rank : 73)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	107	Target Neighborhood Hits	273	Shared Neighborhood Hits	14
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TAB3_HUMAN
NC score	0.019268 (rank : 74)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	107	Target Neighborhood Hits	168	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

CNOT3_HUMAN
NC score	0.018819 (rank : 75)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	107	Target Neighborhood Hits	425	Shared Neighborhood Hits	17
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CNOT3_MOUSE
NC score	0.017739 (rank : 76)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	107	Target Neighborhood Hits	504	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

RPTN_MOUSE
NC score	0.016919 (rank : 77)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	107	Target Neighborhood Hits	650	Shared Neighborhood Hits	12
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

RIMB1_MOUSE
NC score	0.016671 (rank : 78)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	107	Target Neighborhood Hits	1376	Shared Neighborhood Hits	26
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MTMR7_HUMAN
NC score	0.016259 (rank : 79)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	107	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y216, Q68DX4	Gene names	MTMR7
Domain Architecture	No domain graphic available
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

SET1A_HUMAN
NC score	0.015677 (rank : 80)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	107	Target Neighborhood Hits	690	Shared Neighborhood Hits	25
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MUC13_HUMAN
NC score	0.015544 (rank : 81)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	107	Target Neighborhood Hits	164	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

P66A_HUMAN
NC score	0.015232 (rank : 82)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	107	Target Neighborhood Hits	111	Shared Neighborhood Hits	11
SwissProt Accessions	Q86YP4, Q7L3J2, Q96F28, Q9NPU2, Q9NXS1	Gene names	GATAD2A
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A).

TRI66_MOUSE
NC score	0.015203 (rank : 83)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	107	Target Neighborhood Hits	491	Shared Neighborhood Hits	14
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

SPTN5_HUMAN
NC score	0.014882 (rank : 84)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	107	Target Neighborhood Hits	674	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

MUCDL_MOUSE
NC score	0.013969 (rank : 85)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	107	Target Neighborhood Hits	461	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

P66A_MOUSE
NC score	0.012601 (rank : 86)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHY6, Q8BTQ2, Q8VEC9	Gene names	Gatad2a
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (GATA zinc finger domain- containing protein 2A).

ANK2_HUMAN
NC score	0.012463 (rank : 87)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	107	Target Neighborhood Hits	1615	Shared Neighborhood Hits	41
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

TLN2_MOUSE
NC score	0.011188 (rank : 88)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	107	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TRPS1_MOUSE
NC score	0.010309 (rank : 89)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	107	Target Neighborhood Hits	609	Shared Neighborhood Hits	7
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

WDR79_HUMAN
NC score	0.009563 (rank : 90)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	107	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BUR4, Q9NW09	Gene names	WDR79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

MTMR7_MOUSE
NC score	0.008830 (rank : 91)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	107	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2C9, Q8C4J6	Gene names	Mtmr7
Domain Architecture
Description	Myotubularin-related protein 7 (EC 3.1.3.-).

ASPP2_HUMAN
NC score	0.006168 (rank : 92)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	107	Target Neighborhood Hits	1156	Shared Neighborhood Hits	23
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

MEGF9_HUMAN
NC score	0.005518 (rank : 93)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	107	Target Neighborhood Hits	557	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MYO15_HUMAN
NC score	0.004936 (rank : 94)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	107	Target Neighborhood Hits	671	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

ANK3_HUMAN
NC score	0.004935 (rank : 95)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	107	Target Neighborhood Hits	853	Shared Neighborhood Hits	21
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

KCNN1_MOUSE
NC score	0.004686 (rank : 96)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	107	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

CDKL5_HUMAN
NC score	0.004602 (rank : 97)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	107	Target Neighborhood Hits	967	Shared Neighborhood Hits	17
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

WHRN_MOUSE
NC score	0.004411 (rank : 98)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	107	Target Neighborhood Hits	412	Shared Neighborhood Hits	7
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

BMP2K_MOUSE
NC score	0.003406 (rank : 99)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	107	Target Neighborhood Hits	874	Shared Neighborhood Hits	12
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

ZBTB3_HUMAN
NC score	0.003374 (rank : 100)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	107	Target Neighborhood Hits	910	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

NFH_HUMAN
NC score	0.003242 (rank : 101)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	107	Target Neighborhood Hits	1242	Shared Neighborhood Hits	20
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GP125_HUMAN
NC score	0.003047 (rank : 102)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	107	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

PTPRZ_HUMAN
NC score	0.002681 (rank : 103)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	107	Target Neighborhood Hits	255	Shared Neighborhood Hits	8
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PCDA9_HUMAN
NC score	0.002619 (rank : 104)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	107	Target Neighborhood Hits	203	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5H5, O15053	Gene names	PCDHA9, KIAA0345
Domain Architecture
Description	Protocadherin alpha 9 precursor (PCDH-alpha9).

WT1_HUMAN
NC score	0.001889 (rank : 105)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	107	Target Neighborhood Hits	720	Shared Neighborhood Hits	7
SwissProt Accessions	P19544, Q15881, Q16256, Q16575, Q8IYZ5	Gene names	WT1
Domain Architecture
Description	Wilms' tumor protein (WT33).

EGR1_MOUSE
NC score	0.001187 (rank : 106)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	107	Target Neighborhood Hits	816	Shared Neighborhood Hits	13
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

FOXE1_HUMAN
NC score	0.001026 (rank : 107)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	107	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O00358, O75765	Gene names	FOXE1, FKHL15, TITF2, TTF2
Domain Architecture
Description	Forkhead box protein E1 (Thyroid transcription factor 2) (TTF-2) (Forkhead-related protein FKHL15).

AATK_HUMAN
NC score	0.000537 (rank : 108)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	107	Target Neighborhood Hits	1243	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

SPEG_HUMAN
NC score	0.000513 (rank : 109)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	107	Target Neighborhood Hits	1762	Shared Neighborhood Hits	28
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

WT1_MOUSE
NC score	-0.000023 (rank : 110)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	107	Target Neighborhood Hits	723	Shared Neighborhood Hits	5
SwissProt Accessions	P22561	Gene names	Wt1, Wt-1
Domain Architecture
Description	Wilms' tumor protein homolog.

ABL2_HUMAN
NC score	-0.001882 (rank : 111)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	107	Target Neighborhood Hits	1045	Shared Neighborhood Hits	15
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ZAP70_HUMAN
NC score	-0.002602 (rank : 112)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	107	Target Neighborhood Hits	893	Shared Neighborhood Hits	7
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).