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Network neighborhood for query Sequence : GDS1_HUMAN

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GDS1_HUMAN
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GDS1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

IMA2_MOUSE
θ value	8.40245e-06 (rank : 2)	NC score	0.330531 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

ARMC4_HUMAN
θ value	4.1701e-05 (rank : 3)	NC score	0.358632 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

IMA5_HUMAN
θ value	9.29e-05 (rank : 4)	NC score	0.306536 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA2_HUMAN
θ value	0.000461057 (rank : 5)	NC score	0.319884 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

CTND2_HUMAN
θ value	0.00665767 (rank : 6)	NC score	0.193001 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	333	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

CTND2_MOUSE
θ value	0.00665767 (rank : 7)	NC score	0.193781 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

SPAG6_HUMAN
θ value	0.0330416 (rank : 8)	NC score	0.273555 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

CTNB1_HUMAN
θ value	0.0563607 (rank : 9)	NC score	0.237929 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	0.0563607 (rank : 10)	NC score	0.237965 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

SPAG6_MOUSE
θ value	0.0563607 (rank : 11)	NC score	0.269116 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	62	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

IMA7_MOUSE
θ value	0.0736092 (rank : 12)	NC score	0.276837 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

PLAK_HUMAN
θ value	0.0736092 (rank : 13)	NC score	0.219039 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

ATX10_HUMAN
θ value	0.125558 (rank : 14)	NC score	0.127130 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBB4, O14998, O15009, Q6I9X4	Gene names	ATXN10, SCA10
Domain Architecture	No domain graphic available
Description	Ataxin-10 (Spinocerebellar ataxia type 10 protein) (Brain protein E46 homolog).

PLAK_MOUSE
θ value	0.125558 (rank : 15)	NC score	0.228040 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

ARMC6_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.122382 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NXE6, O94999, Q9BTH5	Gene names	ARMC6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

IMA4_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.267469 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

ATX10_MOUSE
θ value	0.279714 (rank : 18)	NC score	0.122444 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P28658, Q543S3, Q99LP5, Q9D1I1	Gene names	Atxn10, Sca10
Domain Architecture	No domain graphic available
Description	Ataxin-10 (Spinocerebellar ataxia type 10 protein homolog) (Brain protein E46).

IMA4_MOUSE
θ value	0.279714 (rank : 19)	NC score	0.265697 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	60	Shared Neighborhood Hits	25
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

CTND1_MOUSE
θ value	0.365318 (rank : 20)	NC score	0.166795 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.164490 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	67	Shared Neighborhood Hits	27
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

IMA1_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.265364 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA7_HUMAN
θ value	0.62314 (rank : 23)	NC score	0.269617 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

STK31_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.040093 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	570	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

IMA1_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.262823 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

IMA3_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.260686 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA3_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.260952 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	56	Shared Neighborhood Hits	26
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

PKP4_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.174868 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	107	Shared Neighborhood Hits	28
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PKP4_MOUSE
θ value	1.38821 (rank : 29)	NC score	0.176464 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	129	Shared Neighborhood Hits	30
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

ARMC6_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.111126 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4	Gene names	Armc6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

PKP3_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.137208 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

BAP29_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.026501 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	285	Shared Neighborhood Hits	3
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

NU133_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.030870 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0G9	Gene names	Nup133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

PKP3_MOUSE
θ value	4.03905 (rank : 34)	NC score	0.133943 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

RIF1_MOUSE
θ value	4.03905 (rank : 35)	NC score	0.028081 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	315	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

APC_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.074198 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	603	Shared Neighborhood Hits	23
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.075853 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	441	Shared Neighborhood Hits	22
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

PKP1_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.124618 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

AB2BP_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.021617 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q96P71, Q5JWF6, Q5JWF7, Q86VV1, Q9H433, Q9H8G8, Q9HBW7, Q9HCQ9	Gene names	APBA2BP, NECAB3, NIP1, XB51
Domain Architecture
Description	Amyloid beta A4 protein-binding family A member 2-binding protein (Neuronal calcium-binding protein 3) (NECAB 3) (X11L-binding protein 51) (Nek2-interacting protein 1).

ARMX3_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.032455 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BHS6, Q91VP8, Q9DC32	Gene names	Armcx3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3.

GNL3_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.019761 (rank : 47)
Query Neighborhood Hits	43	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVP2, Q96SV6, Q96SV7, Q9UJY0	Gene names	GNL3, E2IG3, NS
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin) (E2-induced gene 3-protein) (Novel nucleolar protein 47) (NNP47).

VATH_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.030485 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI12, Q6PK44, Q9H3E3, Q9Y300	Gene names	ATP6V1H
Domain Architecture
Description	Vacuolar ATP synthase subunit H (EC 3.6.3.14) (V-ATPase H subunit) (Vacuolar proton pump subunit H) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit SFD) (VMA13) (Nef-binding protein 1) (NBP1).

VATH_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.030510 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BVE3, Q921X8	Gene names	Atp6v1h
Domain Architecture	No domain graphic available
Description	Vacuolar ATP synthase subunit H (EC 3.6.3.14) (V-ATPase H subunit) (Vacuolar proton pump subunit H).

ARVC_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.148364 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	95	Shared Neighborhood Hits	30
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ARVC_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.149017 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

PKP1_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.118864 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP2_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.111483 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	16
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

Hits sorted by NC score

GDS1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

ARMC4_HUMAN
NC score	0.358632 (rank : 2)	θ value	4.1701e-05 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

IMA2_MOUSE
NC score	0.330531 (rank : 3)	θ value	8.40245e-06 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA2_HUMAN
NC score	0.319884 (rank : 4)	θ value	0.000461057 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA5_HUMAN
NC score	0.306536 (rank : 5)	θ value	9.29e-05 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA7_MOUSE
NC score	0.276837 (rank : 6)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

SPAG6_HUMAN
NC score	0.273555 (rank : 7)	θ value	0.0330416 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

IMA7_HUMAN
NC score	0.269617 (rank : 8)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

SPAG6_MOUSE
NC score	0.269116 (rank : 9)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	62	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

IMA4_HUMAN
NC score	0.267469 (rank : 10)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
NC score	0.265697 (rank : 11)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	60	Shared Neighborhood Hits	25
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA1_HUMAN
NC score	0.265364 (rank : 12)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
NC score	0.262823 (rank : 13)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

IMA3_MOUSE
NC score	0.260952 (rank : 14)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	56	Shared Neighborhood Hits	26
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA3_HUMAN
NC score	0.260686 (rank : 15)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

CTNB1_MOUSE
NC score	0.237965 (rank : 16)	θ value	0.0563607 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.237929 (rank : 17)	θ value	0.0563607 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
NC score	0.228040 (rank : 18)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_HUMAN
NC score	0.219039 (rank : 19)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

CTND2_MOUSE
NC score	0.193781 (rank : 20)	θ value	0.00665767 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CTND2_HUMAN
NC score	0.193001 (rank : 21)	θ value	0.00665767 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	333	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

PKP4_MOUSE
NC score	0.176464 (rank : 22)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	129	Shared Neighborhood Hits	30
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PKP4_HUMAN
NC score	0.174868 (rank : 23)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	107	Shared Neighborhood Hits	28
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

CTND1_MOUSE
NC score	0.166795 (rank : 24)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_HUMAN
NC score	0.164490 (rank : 25)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	67	Shared Neighborhood Hits	27
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

ARVC_MOUSE
NC score	0.149017 (rank : 26)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

ARVC_HUMAN
NC score	0.148364 (rank : 27)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	95	Shared Neighborhood Hits	30
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

PKP3_HUMAN
NC score	0.137208 (rank : 28)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	42	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
NC score	0.133943 (rank : 29)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

ATX10_HUMAN
NC score	0.127130 (rank : 30)	θ value	0.125558 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBB4, O14998, O15009, Q6I9X4	Gene names	ATXN10, SCA10
Domain Architecture	No domain graphic available
Description	Ataxin-10 (Spinocerebellar ataxia type 10 protein) (Brain protein E46 homolog).

PKP1_HUMAN
NC score	0.124618 (rank : 31)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

ATX10_MOUSE
NC score	0.122444 (rank : 32)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P28658, Q543S3, Q99LP5, Q9D1I1	Gene names	Atxn10, Sca10
Domain Architecture	No domain graphic available
Description	Ataxin-10 (Spinocerebellar ataxia type 10 protein homolog) (Brain protein E46).

ARMC6_HUMAN
NC score	0.122382 (rank : 33)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NXE6, O94999, Q9BTH5	Gene names	ARMC6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

PKP1_MOUSE
NC score	0.118864 (rank : 34)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP2_HUMAN
NC score	0.111483 (rank : 35)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	43	Target Neighborhood Hits	40	Shared Neighborhood Hits	16
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

ARMC6_MOUSE
NC score	0.111126 (rank : 36)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4	Gene names	Armc6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

APC_MOUSE
NC score	0.075853 (rank : 37)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	441	Shared Neighborhood Hits	22
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
NC score	0.074198 (rank : 38)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	603	Shared Neighborhood Hits	23
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

STK31_HUMAN
NC score	0.040093 (rank : 39)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	570	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

ARMX3_MOUSE
NC score	0.032455 (rank : 40)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BHS6, Q91VP8, Q9DC32	Gene names	Armcx3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3.

NU133_MOUSE
NC score	0.030870 (rank : 41)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0G9	Gene names	Nup133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

VATH_MOUSE
NC score	0.030510 (rank : 42)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BVE3, Q921X8	Gene names	Atp6v1h
Domain Architecture	No domain graphic available
Description	Vacuolar ATP synthase subunit H (EC 3.6.3.14) (V-ATPase H subunit) (Vacuolar proton pump subunit H).

VATH_HUMAN
NC score	0.030485 (rank : 43)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI12, Q6PK44, Q9H3E3, Q9Y300	Gene names	ATP6V1H
Domain Architecture
Description	Vacuolar ATP synthase subunit H (EC 3.6.3.14) (V-ATPase H subunit) (Vacuolar proton pump subunit H) (V-ATPase 50/57 kDa subunits) (Vacuolar proton pump subunit SFD) (VMA13) (Nef-binding protein 1) (NBP1).

RIF1_MOUSE
NC score	0.028081 (rank : 44)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	315	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

BAP29_MOUSE
NC score	0.026501 (rank : 45)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	285	Shared Neighborhood Hits	3
SwissProt Accessions	Q61334	Gene names	Bcap29, Bap29
Domain Architecture
Description	B-cell receptor-associated protein 29 (BCR-associated protein Bap29).

AB2BP_HUMAN
NC score	0.021617 (rank : 46)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q96P71, Q5JWF6, Q5JWF7, Q86VV1, Q9H433, Q9H8G8, Q9HBW7, Q9HCQ9	Gene names	APBA2BP, NECAB3, NIP1, XB51
Domain Architecture
Description	Amyloid beta A4 protein-binding family A member 2-binding protein (Neuronal calcium-binding protein 3) (NECAB 3) (X11L-binding protein 51) (Nek2-interacting protein 1).

GNL3_HUMAN
NC score	0.019761 (rank : 47)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVP2, Q96SV6, Q96SV7, Q9UJY0	Gene names	GNL3, E2IG3, NS
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein-like 3 (Nucleolar GTP-binding protein 3) (Nucleostemin) (E2-induced gene 3-protein) (Novel nucleolar protein 47) (NNP47).