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Network neighborhood for query Sequence : PKP1_HUMAN

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PKP1_HUMAN
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PKP1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP1_MOUSE
θ value	0 (rank : 2)	NC score	0.998023 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP2_HUMAN
θ value	4.20666e-90 (rank : 3)	NC score	0.948794 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

PKP4_MOUSE
θ value	2.83479e-70 (rank : 4)	NC score	0.902626 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PKP4_HUMAN
θ value	9.11921e-69 (rank : 5)	NC score	0.901647 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

CTND2_HUMAN
θ value	1.45591e-66 (rank : 6)	NC score	0.875279 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

PKP3_HUMAN
θ value	2.74572e-65 (rank : 7)	NC score	0.924726 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
θ value	7.98882e-65 (rank : 8)	NC score	0.924419 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

CTND2_MOUSE
θ value	5.17823e-64 (rank : 9)	NC score	0.886419 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

ARVC_MOUSE
θ value	7.47731e-63 (rank : 10)	NC score	0.907528 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

ARVC_HUMAN
θ value	1.41016e-61 (rank : 11)	NC score	0.904457 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	95	Shared Neighborhood Hits	25
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

CTND1_HUMAN
θ value	6.77864e-56 (rank : 12)	NC score	0.899199 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_MOUSE
θ value	7.49467e-55 (rank : 13)	NC score	0.899782 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

APC_HUMAN
θ value	0.00390308 (rank : 14)	NC score	0.206218 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	603	Shared Neighborhood Hits	24
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	0.00390308 (rank : 15)	NC score	0.212130 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	441	Shared Neighborhood Hits	25
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CTNB1_HUMAN
θ value	0.0330416 (rank : 16)	NC score	0.242453 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	0.0330416 (rank : 17)	NC score	0.242515 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
θ value	0.0330416 (rank : 18)	NC score	0.221648 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	55	Shared Neighborhood Hits	22
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

ARMC4_HUMAN
θ value	0.0736092 (rank : 19)	NC score	0.315721 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

ZF106_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.017839 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	472	Shared Neighborhood Hits	3
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

IMA3_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.060548 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	53	Shared Neighborhood Hits	19
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

SGOL2_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.026955 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

ZYGBL_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.039555 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z7L7, O00156, Q5T272, Q5T273	Gene names	ZYG11BL, C9orf60, ZYG
Domain Architecture	No domain graphic available
Description	Zyg-11 protein homolog (Zyg-11 homolog B-like).

ZYGBL_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.039639 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q80ZJ6, Q6PGH5, Q8BG38	Gene names	Zyg11bl, Zyg
Domain Architecture	No domain graphic available
Description	Zyg-11 protein homolog (Zyg-11 homolog B-like).

LRP10_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.010531 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

ARMX3_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.041427 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UH62, Q53HC6, Q7LCF5, Q9NPE4	Gene names	ARMCX3, ALEX3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3 (Protein ALEX3) (ARM protein lost in epithelial cancers on chromosome X 3).

GDS1_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.124618 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

RAD_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.004913 (rank : 41)
Query Neighborhood Hits	36	Target Neighborhood Hits	224	Shared Neighborhood Hits	3
SwissProt Accessions	P55042, Q96F39	Gene names	RRAD, RAD
Domain Architecture
Description	GTP-binding protein RAD (RAS associated with diabetes) (RAD1).

SPAG6_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.029679 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

COG4_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.010281 (rank : 39)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H9E3, Q96D40, Q9BRF0, Q9BVZ2, Q9H5Y4, Q9Y3W3	Gene names	COG4
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 4.

CX020_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.014366 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NDZ0, Q5JXE5	Gene names	CXorf20
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf20.

IMA3_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.058793 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA4_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.061149 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	59	Shared Neighborhood Hits	18
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.061203 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

DPOLZ_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.007925 (rank : 40)
Query Neighborhood Hits	36	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

PLAK_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.182749 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

IMA2_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.060541 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.060782 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA5_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.068448 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA7_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.070488 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA7_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.073218 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

Hits sorted by NC score

PKP1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP1_MOUSE
NC score	0.998023 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP2_HUMAN
NC score	0.948794 (rank : 3)	θ value	4.20666e-90 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

PKP3_HUMAN
NC score	0.924726 (rank : 4)	θ value	2.74572e-65 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	42	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
NC score	0.924419 (rank : 5)	θ value	7.98882e-65 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

ARVC_MOUSE
NC score	0.907528 (rank : 6)	θ value	7.47731e-63 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

ARVC_HUMAN
NC score	0.904457 (rank : 7)	θ value	1.41016e-61 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	95	Shared Neighborhood Hits	25
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

PKP4_MOUSE
NC score	0.902626 (rank : 8)	θ value	2.83479e-70 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PKP4_HUMAN
NC score	0.901647 (rank : 9)	θ value	9.11921e-69 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

CTND1_MOUSE
NC score	0.899782 (rank : 10)	θ value	7.49467e-55 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_HUMAN
NC score	0.899199 (rank : 11)	θ value	6.77864e-56 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND2_MOUSE
NC score	0.886419 (rank : 12)	θ value	5.17823e-64 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CTND2_HUMAN
NC score	0.875279 (rank : 13)	θ value	1.45591e-66 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	333	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

ARMC4_HUMAN
NC score	0.315721 (rank : 14)	θ value	0.0736092 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CTNB1_MOUSE
NC score	0.242515 (rank : 15)	θ value	0.0330416 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.242453 (rank : 16)	θ value	0.0330416 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
NC score	0.221648 (rank : 17)	θ value	0.0330416 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	55	Shared Neighborhood Hits	22
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

APC_MOUSE
NC score	0.212130 (rank : 18)	θ value	0.00390308 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	441	Shared Neighborhood Hits	25
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
NC score	0.206218 (rank : 19)	θ value	0.00390308 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	603	Shared Neighborhood Hits	24
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

PLAK_HUMAN
NC score	0.182749 (rank : 20)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

GDS1_HUMAN
NC score	0.124618 (rank : 21)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	43	Shared Neighborhood Hits	22
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

IMA7_MOUSE
NC score	0.073218 (rank : 22)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA7_HUMAN
NC score	0.070488 (rank : 23)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA5_HUMAN
NC score	0.068448 (rank : 24)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA4_MOUSE
NC score	0.061203 (rank : 25)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	18
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA4_HUMAN
NC score	0.061149 (rank : 26)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	59	Shared Neighborhood Hits	18
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA2_MOUSE
NC score	0.060782 (rank : 27)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA3_HUMAN
NC score	0.060548 (rank : 28)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	53	Shared Neighborhood Hits	19
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA2_HUMAN
NC score	0.060541 (rank : 29)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA3_MOUSE
NC score	0.058793 (rank : 30)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

ARMX3_HUMAN
NC score	0.041427 (rank : 31)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	38	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UH62, Q53HC6, Q7LCF5, Q9NPE4	Gene names	ARMCX3, ALEX3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3 (Protein ALEX3) (ARM protein lost in epithelial cancers on chromosome X 3).

ZYGBL_MOUSE
NC score	0.039639 (rank : 32)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q80ZJ6, Q6PGH5, Q8BG38	Gene names	Zyg11bl, Zyg
Domain Architecture	No domain graphic available
Description	Zyg-11 protein homolog (Zyg-11 homolog B-like).

ZYGBL_HUMAN
NC score	0.039555 (rank : 33)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z7L7, O00156, Q5T272, Q5T273	Gene names	ZYG11BL, C9orf60, ZYG
Domain Architecture	No domain graphic available
Description	Zyg-11 protein homolog (Zyg-11 homolog B-like).

SPAG6_HUMAN
NC score	0.029679 (rank : 34)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	58	Shared Neighborhood Hits	13
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

SGOL2_MOUSE
NC score	0.026955 (rank : 35)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

ZF106_MOUSE
NC score	0.017839 (rank : 36)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	472	Shared Neighborhood Hits	3
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

CX020_HUMAN
NC score	0.014366 (rank : 37)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NDZ0, Q5JXE5	Gene names	CXorf20
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf20.

LRP10_MOUSE
NC score	0.010531 (rank : 38)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	169	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

COG4_HUMAN
NC score	0.010281 (rank : 39)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H9E3, Q96D40, Q9BRF0, Q9BVZ2, Q9H5Y4, Q9Y3W3	Gene names	COG4
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 4.

DPOLZ_HUMAN
NC score	0.007925 (rank : 40)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

RAD_HUMAN
NC score	0.004913 (rank : 41)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	224	Shared Neighborhood Hits	3
SwissProt Accessions	P55042, Q96F39	Gene names	RRAD, RAD
Domain Architecture
Description	GTP-binding protein RAD (RAS associated with diabetes) (RAD1).