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Network neighborhood for query Sequence : PKP3_MOUSE

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PKP3_MOUSE
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PKP3_HUMAN
θ value	0 (rank : 1)	NC score	0.997772 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

PKP1_MOUSE
θ value	2.65329e-68 (rank : 3)	NC score	0.927583 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP4_MOUSE
θ value	2.93355e-67 (rank : 4)	NC score	0.900334 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	129	Shared Neighborhood Hits	23
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PKP1_HUMAN
θ value	7.98882e-65 (rank : 5)	NC score	0.924419 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

ARVC_HUMAN
θ value	8.83269e-64 (rank : 6)	NC score	0.909052 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

CTND2_HUMAN
θ value	8.83269e-64 (rank : 7)	NC score	0.874562 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	333	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

PKP4_HUMAN
θ value	1.50663e-63 (rank : 8)	NC score	0.898165 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	107	Shared Neighborhood Hits	23
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

ARVC_MOUSE
θ value	5.7252e-63 (rank : 9)	NC score	0.911166 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	67	Shared Neighborhood Hits	22
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

CTND1_HUMAN
θ value	1.84173e-61 (rank : 10)	NC score	0.906203 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	67	Shared Neighborhood Hits	23
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_MOUSE
θ value	2.03627e-60 (rank : 11)	NC score	0.906293 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND2_MOUSE
θ value	3.47335e-60 (rank : 12)	NC score	0.884846 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	227	Shared Neighborhood Hits	23
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

PKP2_HUMAN
θ value	1.23536e-57 (rank : 13)	NC score	0.922045 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	18
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

PLAK_MOUSE
θ value	0.00298849 (rank : 14)	NC score	0.239405 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_HUMAN
θ value	0.00665767 (rank : 15)	NC score	0.207855 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

ARMC4_HUMAN
θ value	0.00869519 (rank : 16)	NC score	0.337480 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CTNB1_HUMAN
θ value	0.0961366 (rank : 17)	NC score	0.254992 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	0.0961366 (rank : 18)	NC score	0.255047 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

NFKB1_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.018046 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

UBL7_HUMAN
θ value	0.62314 (rank : 20)	NC score	0.029659 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q96S82, Q96I03	Gene names	UBL7, BMSCUBP
Domain Architecture
Description	Ubiquitin-like protein 7 (Ubiquitin-like protein SB132) (Bone marrow stromal cell ubiquitin-like protein) (BMSC-UbP).

SYNE1_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.011261 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	1484	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

AIRE_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.018514 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

APC_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.172223 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	603	Shared Neighborhood Hits	25
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.177151 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	441	Shared Neighborhood Hits	25
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ERC2_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.009993 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	1156	Shared Neighborhood Hits	7
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	1.06291 (rank : 26)	NC score	0.010013 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	1166	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ZBT7A_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.000398 (rank : 51)
Query Neighborhood Hits	46	Target Neighborhood Hits	795	Shared Neighborhood Hits	3
SwissProt Accessions	O88939, Q9CRJ0	Gene names	Zbtb7a, Lrf, Zbtb7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor).

SMOC2_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.019409 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

TNPO2_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.032914 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.032877 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

ZBT7A_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.000086 (rank : 52)
Query Neighborhood Hits	46	Target Neighborhood Hits	823	Shared Neighborhood Hits	3
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).

GDS1_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.133943 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

RB6I2_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.005876 (rank : 47)
Query Neighborhood Hits	46	Target Neighborhood Hits	1584	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

TIF1A_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.010332 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	4.03905 (rank : 35)	NC score	0.010519 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TNPO1_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.029301 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	64	Shared Neighborhood Hits	8
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.028084 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TTF1_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.025934 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

IMA5_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.066877 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	68	Shared Neighborhood Hits	22
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

KCNK7_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.007206 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

MSX1_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.001216 (rank : 50)
Query Neighborhood Hits	46	Target Neighborhood Hits	374	Shared Neighborhood Hits	2
SwissProt Accessions	P28360, Q96NY4	Gene names	MSX1, HOX7
Domain Architecture
Description	Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7).

YTHD3_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.007405 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYK6, Q3UVI5, Q6NXJ6, Q6NXJ8, Q8BKB6	Gene names	Ythdf3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

FUT4_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.005660 (rank : 48)
Query Neighborhood Hits	46	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q11127	Gene names	Fut4, Elft
Domain Architecture
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 4) (FUCT-IV) (Fuc-TIV).

IMA3_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.050492 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

KIF2C_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.002105 (rank : 49)
Query Neighborhood Hits	46	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

SMOC2_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.010955 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

IMA2_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.055977 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.055971 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA4_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.052205 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.052278 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	60	Shared Neighborhood Hits	19
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA7_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.065787 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA7_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.068147 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

Hits sorted by NC score

PKP3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

PKP3_HUMAN
NC score	0.997772 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	46	Target Neighborhood Hits	42	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP1_MOUSE
NC score	0.927583 (rank : 3)	θ value	2.65329e-68 (rank : 3)
Query Neighborhood Hits	46	Target Neighborhood Hits	37	Shared Neighborhood Hits	21
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP1_HUMAN
NC score	0.924419 (rank : 4)	θ value	7.98882e-65 (rank : 5)
Query Neighborhood Hits	46	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP2_HUMAN
NC score	0.922045 (rank : 5)	θ value	1.23536e-57 (rank : 13)
Query Neighborhood Hits	46	Target Neighborhood Hits	40	Shared Neighborhood Hits	18
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

ARVC_MOUSE
NC score	0.911166 (rank : 6)	θ value	5.7252e-63 (rank : 9)
Query Neighborhood Hits	46	Target Neighborhood Hits	67	Shared Neighborhood Hits	22
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

ARVC_HUMAN
NC score	0.909052 (rank : 7)	θ value	8.83269e-64 (rank : 6)
Query Neighborhood Hits	46	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

CTND1_MOUSE
NC score	0.906293 (rank : 8)	θ value	2.03627e-60 (rank : 11)
Query Neighborhood Hits	46	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_HUMAN
NC score	0.906203 (rank : 9)	θ value	1.84173e-61 (rank : 10)
Query Neighborhood Hits	46	Target Neighborhood Hits	67	Shared Neighborhood Hits	23
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

PKP4_MOUSE
NC score	0.900334 (rank : 10)	θ value	2.93355e-67 (rank : 4)
Query Neighborhood Hits	46	Target Neighborhood Hits	129	Shared Neighborhood Hits	23
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PKP4_HUMAN
NC score	0.898165 (rank : 11)	θ value	1.50663e-63 (rank : 8)
Query Neighborhood Hits	46	Target Neighborhood Hits	107	Shared Neighborhood Hits	23
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

CTND2_MOUSE
NC score	0.884846 (rank : 12)	θ value	3.47335e-60 (rank : 12)
Query Neighborhood Hits	46	Target Neighborhood Hits	227	Shared Neighborhood Hits	23
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CTND2_HUMAN
NC score	0.874562 (rank : 13)	θ value	8.83269e-64 (rank : 7)
Query Neighborhood Hits	46	Target Neighborhood Hits	333	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

ARMC4_HUMAN
NC score	0.337480 (rank : 14)	θ value	0.00869519 (rank : 16)
Query Neighborhood Hits	46	Target Neighborhood Hits	88	Shared Neighborhood Hits	23
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CTNB1_MOUSE
NC score	0.255047 (rank : 15)	θ value	0.0961366 (rank : 18)
Query Neighborhood Hits	46	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.254992 (rank : 16)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	46	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
NC score	0.239405 (rank : 17)	θ value	0.00298849 (rank : 14)
Query Neighborhood Hits	46	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_HUMAN
NC score	0.207855 (rank : 18)	θ value	0.00665767 (rank : 15)
Query Neighborhood Hits	46	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

APC_MOUSE
NC score	0.177151 (rank : 19)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	46	Target Neighborhood Hits	441	Shared Neighborhood Hits	25
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
NC score	0.172223 (rank : 20)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	46	Target Neighborhood Hits	603	Shared Neighborhood Hits	25
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

GDS1_HUMAN
NC score	0.133943 (rank : 21)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	46	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

IMA7_MOUSE
NC score	0.068147 (rank : 22)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	46	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA5_HUMAN
NC score	0.066877 (rank : 23)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	46	Target Neighborhood Hits	68	Shared Neighborhood Hits	22
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA7_HUMAN
NC score	0.065787 (rank : 24)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	46	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA2_HUMAN
NC score	0.055977 (rank : 25)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	46	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
NC score	0.055971 (rank : 26)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	46	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA4_MOUSE
NC score	0.052278 (rank : 27)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	46	Target Neighborhood Hits	60	Shared Neighborhood Hits	19
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA4_HUMAN
NC score	0.052205 (rank : 28)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	46	Target Neighborhood Hits	59	Shared Neighborhood Hits	19
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA3_MOUSE
NC score	0.050492 (rank : 29)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	46	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

TNPO2_HUMAN
NC score	0.032914 (rank : 30)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	46	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
NC score	0.032877 (rank : 31)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	46	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

UBL7_HUMAN
NC score	0.029659 (rank : 32)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	46	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q96S82, Q96I03	Gene names	UBL7, BMSCUBP
Domain Architecture
Description	Ubiquitin-like protein 7 (Ubiquitin-like protein SB132) (Bone marrow stromal cell ubiquitin-like protein) (BMSC-UbP).

TNPO1_HUMAN
NC score	0.029301 (rank : 33)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	46	Target Neighborhood Hits	64	Shared Neighborhood Hits	8
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
NC score	0.028084 (rank : 34)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	46	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TTF1_MOUSE
NC score	0.025934 (rank : 35)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	46	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

SMOC2_HUMAN
NC score	0.019409 (rank : 36)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	46	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

AIRE_MOUSE
NC score	0.018514 (rank : 37)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	46	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

NFKB1_HUMAN
NC score	0.018046 (rank : 38)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	46	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

SYNE1_HUMAN
NC score	0.011261 (rank : 39)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	46	Target Neighborhood Hits	1484	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SMOC2_MOUSE
NC score	0.010955 (rank : 40)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	46	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

TIF1A_MOUSE
NC score	0.010519 (rank : 41)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	46	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1A_HUMAN
NC score	0.010332 (rank : 42)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	46	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

ERC2_MOUSE
NC score	0.010013 (rank : 43)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	46	Target Neighborhood Hits	1166	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ERC2_HUMAN
NC score	0.009993 (rank : 44)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	46	Target Neighborhood Hits	1156	Shared Neighborhood Hits	7
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

YTHD3_MOUSE
NC score	0.007405 (rank : 45)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	46	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BYK6, Q3UVI5, Q6NXJ6, Q6NXJ8, Q8BKB6	Gene names	Ythdf3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

KCNK7_MOUSE
NC score	0.007206 (rank : 46)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	46	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

RB6I2_HUMAN
NC score	0.005876 (rank : 47)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	46	Target Neighborhood Hits	1584	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

FUT4_MOUSE
NC score	0.005660 (rank : 48)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	46	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q11127	Gene names	Fut4, Elft
Domain Architecture
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 4) (FUCT-IV) (Fuc-TIV).

KIF2C_HUMAN
NC score	0.002105 (rank : 49)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	46	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q99661, Q96C18, Q96HB8, Q9BWV8	Gene names	KIF2C, KNSL6
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK) (Kinesin-like protein 6).

MSX1_HUMAN
NC score	0.001216 (rank : 50)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	46	Target Neighborhood Hits	374	Shared Neighborhood Hits	2
SwissProt Accessions	P28360, Q96NY4	Gene names	MSX1, HOX7
Domain Architecture
Description	Homeobox protein MSX-1 (Msh homeobox 1-like protein) (Hox-7).

ZBT7A_MOUSE
NC score	0.000398 (rank : 51)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	46	Target Neighborhood Hits	795	Shared Neighborhood Hits	3
SwissProt Accessions	O88939, Q9CRJ0	Gene names	Zbtb7a, Lrf, Zbtb7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor).

ZBT7A_HUMAN
NC score	0.000086 (rank : 52)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	46	Target Neighborhood Hits	823	Shared Neighborhood Hits	3
SwissProt Accessions	O95365, O00456	Gene names	ZBTB7A, FBI1, LRF, ZBTB7
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 7A (Leukemia/lymphoma- related factor) (Factor that binds to inducer of short transcripts protein 1) (Factor binding IST protein 1) (FBI-1) (HIV-1 1st-binding protein 1) (TTF-I-interacting peptide 21) (TIP21).