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Network neighborhood for query Sequence : ARMC4_HUMAN

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ARMC4_HUMAN
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARMC4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

PLAK_MOUSE
θ value	5.43371e-13 (rank : 2)	NC score	0.541346 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_HUMAN
θ value	1.2105e-12 (rank : 3)	NC score	0.525006 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

CTNB1_HUMAN
θ value	7.84624e-12 (rank : 4)	NC score	0.542489 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	7.84624e-12 (rank : 5)	NC score	0.542554 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

IMA2_MOUSE
θ value	2.36244e-08 (rank : 6)	NC score	0.323748 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA2_HUMAN
θ value	1.17247e-07 (rank : 7)	NC score	0.327542 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

ARVC_HUMAN
θ value	5.81887e-07 (rank : 8)	NC score	0.405117 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	95	Shared Neighborhood Hits	40
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ARVC_MOUSE
θ value	7.59969e-07 (rank : 9)	NC score	0.406518 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

CTND2_HUMAN
θ value	1.29631e-06 (rank : 10)	NC score	0.381228 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	333	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

SPAG6_HUMAN
θ value	1.09739e-05 (rank : 11)	NC score	0.331200 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

IMA5_HUMAN
θ value	1.43324e-05 (rank : 12)	NC score	0.286632 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

GDS1_HUMAN
θ value	4.1701e-05 (rank : 13)	NC score	0.358632 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	33
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

PKP4_MOUSE
θ value	4.1701e-05 (rank : 14)	NC score	0.378102 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	129	Shared Neighborhood Hits	39
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

CTND1_MOUSE
θ value	7.1131e-05 (rank : 15)	NC score	0.376962 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	69	Shared Neighborhood Hits	38
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND1_HUMAN
θ value	9.29e-05 (rank : 16)	NC score	0.379171 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

SPAG6_MOUSE
θ value	9.29e-05 (rank : 17)	NC score	0.315536 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

CTND2_MOUSE
θ value	0.00228821 (rank : 18)	NC score	0.370310 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

PKP4_HUMAN
θ value	0.00298849 (rank : 19)	NC score	0.365895 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	34
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PKP3_MOUSE
θ value	0.00869519 (rank : 20)	NC score	0.337480 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

PKP3_HUMAN
θ value	0.0113563 (rank : 21)	NC score	0.340242 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

RTDR1_HUMAN
θ value	0.0148317 (rank : 22)	NC score	0.210093 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

ARMC6_MOUSE
θ value	0.0563607 (rank : 23)	NC score	0.141172 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4	Gene names	Armc6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

IMA7_HUMAN
θ value	0.0563607 (rank : 24)	NC score	0.246506 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

ARMC7_HUMAN
θ value	0.0736092 (rank : 25)	NC score	0.183150 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H6L4	Gene names	ARMC7
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 7.

PKP1_HUMAN
θ value	0.0736092 (rank : 26)	NC score	0.315721 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

ARMX3_HUMAN
θ value	0.279714 (rank : 27)	NC score	0.109800 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UH62, Q53HC6, Q7LCF5, Q9NPE4	Gene names	ARMCX3, ALEX3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3 (Protein ALEX3) (ARM protein lost in epithelial cancers on chromosome X 3).

PKP1_MOUSE
θ value	0.279714 (rank : 28)	NC score	0.319937 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP2_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.307080 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

RIF1_HUMAN
θ value	0.365318 (rank : 30)	NC score	0.047206 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	320	Shared Neighborhood Hits	6
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

IMA3_MOUSE
θ value	0.47712 (rank : 31)	NC score	0.232022 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

ARMC7_MOUSE
θ value	0.62314 (rank : 32)	NC score	0.161610 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UJZ3, Q8R599	Gene names	Armc7
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 7.

GGA1_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.041421 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

SETBP_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.041126 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

IMA3_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.230273 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA7_MOUSE
θ value	0.813845 (rank : 36)	NC score	0.238076 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

TRRAP_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.037523 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

HOME2_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.021913 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	882	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

KIFA3_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.062416 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P70188, P70189	Gene names	Kifap3
Domain Architecture
Description	Kinesin-associated protein 3 (KAP3).

K0146_MOUSE
θ value	1.38821 (rank : 40)	NC score	0.040393 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGX7, Q3TCD0, Q5U457, Q6A0B6, Q6IS60, Q811E1, Q8BWD6, Q8R305	Gene names	Kiaa0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

KIFA3_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.060566 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).

IFT74_MOUSE
θ value	1.81305 (rank : 42)	NC score	0.018004 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	939	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IWS1_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.018374 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	1241	Shared Neighborhood Hits	13
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ARMX2_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.070904 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	134	Shared Neighborhood Hits	16
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

ARMX2_MOUSE
θ value	2.36792 (rank : 45)	NC score	0.067156 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

GGA1_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.035626 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

TTC12_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.036587 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

2AAB_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.035873 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

APC_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.133098 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	603	Shared Neighborhood Hits	33
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

APC_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.136005 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	441	Shared Neighborhood Hits	30
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

ARMX3_MOUSE
θ value	3.0926 (rank : 51)	NC score	0.100546 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BHS6, Q91VP8, Q9DC32	Gene names	Armcx3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3.

IMA4_MOUSE
θ value	3.0926 (rank : 52)	NC score	0.233555 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

SART3_MOUSE
θ value	3.0926 (rank : 53)	NC score	0.018343 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	341	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLI8, Q6ZQI2, Q8BPK9, Q8C3B7, Q8CFU9	Gene names	Sart3, Kiaa0156
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (mSART-3) (Tumor-rejection antigen SART3).

SMC1A_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.015831 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	1346	Shared Neighborhood Hits	13
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.014984 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	1384	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

AP2B1_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.036830 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.036832 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

ARMX1_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.071304 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P291, Q53HK2, Q9H2Q0	Gene names	ARMCX1, ALEX1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1 (Protein ALEX1) (ARM protein lost in epithelial cancers on chromosome X 1).

ARMX1_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.068151 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CX83	Gene names	Armcx1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1.

DYNA_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.012071 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	1194	Shared Neighborhood Hits	13
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

IMA1_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.226744 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.226186 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

IMA4_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.232719 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	33
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

SARM1_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.053662 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

SARM1_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.052982 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

2AAB_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.027404 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

AP1B1_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.035545 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q10567, P78436	Gene names	AP1B1, ADTB1, BAM22
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

AP1B1_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.035676 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	O35643, Q922E2	Gene names	Ap1b1, Adtb1
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

CCD46_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.008348 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	1405	Shared Neighborhood Hits	13
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

JHD2C_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.013922 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	297	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

LHFP_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.020731 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BM86, Q3T9G7, Q3TWU2	Gene names	Lhfp
Domain Architecture	No domain graphic available
Description	Lipoma HMGIC fusion partner precursor.

RHG26_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.009867 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RIC8B_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.028187 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVN3, Q4G103, Q6ZRN4, Q86WD3	Gene names	RIC8B
Domain Architecture	No domain graphic available
Description	Synembryn-B (Brain synembrin) (hSyn) (Protein Ric-8B).

RIC8B_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.027933 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XE1, Q58L65	Gene names	Ric8b
Domain Architecture	No domain graphic available
Description	Synembryn-B (Protein Ric-8B).

ROCK1_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.002191 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	2000	Shared Neighborhood Hits	11
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK1_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.001999 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	2126	Shared Neighborhood Hits	13
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SFR11_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.027857 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	246	Shared Neighborhood Hits	8
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

UN45A_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.042511 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

ACOX3_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.014030 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPL9	Gene names	Acox3
Domain Architecture
Description	Acyl-coenzyme A oxidase 3, peroxisomal (EC 1.3.3.6) (Pristanoyl-CoA oxidase) (Branched-chain acyl-CoA oxidase) (BRCACox).

ANK3_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.004192 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	853	Shared Neighborhood Hits	11
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

NCKX6_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.018036 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q6J4K2, Q4KMS9, Q6J4K1, Q9H6I8	Gene names	SLC24A6, NCKX6, NCLX
Domain Architecture	No domain graphic available
Description	Sodium/potassium/calcium exchanger 6 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) (Solute carrier family 24 member 6).

WBP4_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.021419 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

ARMC6_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.092125 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NXE6, O94999, Q9BTH5	Gene names	ARMC6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

CNGA1_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.006397 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

COA1_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.010715 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

GP158_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.012730 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	221	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

SFR12_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.016425 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	553	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SFRS4_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.009242 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	406	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

Hits sorted by NC score

ARMC4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CTNB1_MOUSE
NC score	0.542554 (rank : 2)	θ value	7.84624e-12 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	37
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.542489 (rank : 3)	θ value	7.84624e-12 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
NC score	0.541346 (rank : 4)	θ value	5.43371e-13 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_HUMAN
NC score	0.525006 (rank : 5)	θ value	1.2105e-12 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

ARVC_MOUSE
NC score	0.406518 (rank : 6)	θ value	7.59969e-07 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

ARVC_HUMAN
NC score	0.405117 (rank : 7)	θ value	5.81887e-07 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	95	Shared Neighborhood Hits	40
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

CTND2_HUMAN
NC score	0.381228 (rank : 8)	θ value	1.29631e-06 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	333	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

CTND1_HUMAN
NC score	0.379171 (rank : 9)	θ value	9.29e-05 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

PKP4_MOUSE
NC score	0.378102 (rank : 10)	θ value	4.1701e-05 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	129	Shared Neighborhood Hits	39
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

CTND1_MOUSE
NC score	0.376962 (rank : 11)	θ value	7.1131e-05 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	69	Shared Neighborhood Hits	38
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

CTND2_MOUSE
NC score	0.370310 (rank : 12)	θ value	0.00228821 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

PKP4_HUMAN
NC score	0.365895 (rank : 13)	θ value	0.00298849 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	107	Shared Neighborhood Hits	34
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

GDS1_HUMAN
NC score	0.358632 (rank : 14)	θ value	4.1701e-05 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	33
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

PKP3_HUMAN
NC score	0.340242 (rank : 15)	θ value	0.0113563 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
NC score	0.337480 (rank : 16)	θ value	0.00869519 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

SPAG6_HUMAN
NC score	0.331200 (rank : 17)	θ value	1.09739e-05 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

IMA2_HUMAN
NC score	0.327542 (rank : 18)	θ value	1.17247e-07 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
NC score	0.323748 (rank : 19)	θ value	2.36244e-08 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	29
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

PKP1_MOUSE
NC score	0.319937 (rank : 20)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP1_HUMAN
NC score	0.315721 (rank : 21)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

SPAG6_MOUSE
NC score	0.315536 (rank : 22)	θ value	9.29e-05 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

PKP2_HUMAN
NC score	0.307080 (rank : 23)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q99959, Q99960	Gene names	PKP2
Domain Architecture
Description	Plakophilin-2.

IMA5_HUMAN
NC score	0.286632 (rank : 24)	θ value	1.43324e-05 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA7_HUMAN
NC score	0.246506 (rank : 25)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA7_MOUSE
NC score	0.238076 (rank : 26)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA4_MOUSE
NC score	0.233555 (rank : 27)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	60	Shared Neighborhood Hits	33
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA4_HUMAN
NC score	0.232719 (rank : 28)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	33
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA3_MOUSE
NC score	0.232022 (rank : 29)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA3_HUMAN
NC score	0.230273 (rank : 30)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA1_HUMAN
NC score	0.226744 (rank : 31)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
NC score	0.226186 (rank : 32)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

RTDR1_HUMAN
NC score	0.210093 (rank : 33)	θ value	0.0148317 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

ARMC7_HUMAN
NC score	0.183150 (rank : 34)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H6L4	Gene names	ARMC7
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 7.

ARMC7_MOUSE
NC score	0.161610 (rank : 35)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UJZ3, Q8R599	Gene names	Armc7
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 7.

ARMC6_MOUSE
NC score	0.141172 (rank : 36)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4	Gene names	Armc6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

APC_MOUSE
NC score	0.136005 (rank : 37)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	441	Shared Neighborhood Hits	30
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

APC_HUMAN
NC score	0.133098 (rank : 38)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	603	Shared Neighborhood Hits	33
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ARMX3_HUMAN
NC score	0.109800 (rank : 39)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UH62, Q53HC6, Q7LCF5, Q9NPE4	Gene names	ARMCX3, ALEX3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3 (Protein ALEX3) (ARM protein lost in epithelial cancers on chromosome X 3).

ARMX3_MOUSE
NC score	0.100546 (rank : 40)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BHS6, Q91VP8, Q9DC32	Gene names	Armcx3
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 3.

ARMC6_HUMAN
NC score	0.092125 (rank : 41)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	Q6NXE6, O94999, Q9BTH5	Gene names	ARMC6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

ARMX1_HUMAN
NC score	0.071304 (rank : 42)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P291, Q53HK2, Q9H2Q0	Gene names	ARMCX1, ALEX1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1 (Protein ALEX1) (ARM protein lost in epithelial cancers on chromosome X 1).

ARMX2_HUMAN
NC score	0.070904 (rank : 43)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	134	Shared Neighborhood Hits	16
SwissProt Accessions	Q7L311, O60267, Q5H9D9	Gene names	ARMCX2, ALEX2, KIAA0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2 (Protein ALEX2) (ARM protein lost in epithelial cancers on chromosome X 2).

ARMX1_MOUSE
NC score	0.068151 (rank : 44)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	41	Shared Neighborhood Hits	17
SwissProt Accessions	Q9CX83	Gene names	Armcx1
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 1.

ARMX2_MOUSE
NC score	0.067156 (rank : 45)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q6A058, Q9CXI9	Gene names	Armcx2, Kiaa0512
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing X-linked protein 2.

KIFA3_MOUSE
NC score	0.062416 (rank : 46)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P70188, P70189	Gene names	Kifap3
Domain Architecture
Description	Kinesin-associated protein 3 (KAP3).

KIFA3_HUMAN
NC score	0.060566 (rank : 47)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).

SARM1_HUMAN
NC score	0.053662 (rank : 48)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

SARM1_MOUSE
NC score	0.052982 (rank : 49)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

RIF1_HUMAN
NC score	0.047206 (rank : 50)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	320	Shared Neighborhood Hits	6
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

UN45A_HUMAN
NC score	0.042511 (rank : 51)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

GGA1_MOUSE
NC score	0.041421 (rank : 52)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

SETBP_MOUSE
NC score	0.041126 (rank : 53)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

K0146_MOUSE
NC score	0.040393 (rank : 54)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGX7, Q3TCD0, Q5U457, Q6A0B6, Q6IS60, Q811E1, Q8BWD6, Q8R305	Gene names	Kiaa0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

TRRAP_HUMAN
NC score	0.037523 (rank : 55)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

AP2B1_MOUSE
NC score	0.036832 (rank : 56)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_HUMAN
NC score	0.036830 (rank : 57)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

TTC12_HUMAN
NC score	0.036587 (rank : 58)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	125	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

2AAB_MOUSE
NC score	0.035873 (rank : 59)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

AP1B1_MOUSE
NC score	0.035676 (rank : 60)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	O35643, Q922E2	Gene names	Ap1b1, Adtb1
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

GGA1_HUMAN
NC score	0.035626 (rank : 61)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

AP1B1_HUMAN
NC score	0.035545 (rank : 62)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q10567, P78436	Gene names	AP1B1, ADTB1, BAM22
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

RIC8B_HUMAN
NC score	0.028187 (rank : 63)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVN3, Q4G103, Q6ZRN4, Q86WD3	Gene names	RIC8B
Domain Architecture	No domain graphic available
Description	Synembryn-B (Brain synembrin) (hSyn) (Protein Ric-8B).

RIC8B_MOUSE
NC score	0.027933 (rank : 64)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XE1, Q58L65	Gene names	Ric8b
Domain Architecture	No domain graphic available
Description	Synembryn-B (Protein Ric-8B).

SFR11_HUMAN
NC score	0.027857 (rank : 65)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	246	Shared Neighborhood Hits	8
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

2AAB_HUMAN
NC score	0.027404 (rank : 66)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

HOME2_MOUSE
NC score	0.021913 (rank : 67)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	882	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

WBP4_MOUSE
NC score	0.021419 (rank : 68)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q61048, Q8K1Z9, Q9CS45	Gene names	Wbp4, Fbp21, Fnbp21
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21).

LHFP_MOUSE
NC score	0.020731 (rank : 69)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BM86, Q3T9G7, Q3TWU2	Gene names	Lhfp
Domain Architecture	No domain graphic available
Description	Lipoma HMGIC fusion partner precursor.

IWS1_HUMAN
NC score	0.018374 (rank : 70)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	1241	Shared Neighborhood Hits	13
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SART3_MOUSE
NC score	0.018343 (rank : 71)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	341	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLI8, Q6ZQI2, Q8BPK9, Q8C3B7, Q8CFU9	Gene names	Sart3, Kiaa0156
Domain Architecture	No domain graphic available
Description	Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (mSART-3) (Tumor-rejection antigen SART3).

NCKX6_HUMAN
NC score	0.018036 (rank : 72)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q6J4K2, Q4KMS9, Q6J4K1, Q9H6I8	Gene names	SLC24A6, NCKX6, NCLX
Domain Architecture	No domain graphic available
Description	Sodium/potassium/calcium exchanger 6 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 6) (Solute carrier family 24 member 6).

IFT74_MOUSE
NC score	0.018004 (rank : 73)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	939	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

SFR12_HUMAN
NC score	0.016425 (rank : 74)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	553	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

SMC1A_HUMAN
NC score	0.015831 (rank : 75)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	1346	Shared Neighborhood Hits	13
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
NC score	0.014984 (rank : 76)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	1384	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

ACOX3_MOUSE
NC score	0.014030 (rank : 77)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPL9	Gene names	Acox3
Domain Architecture
Description	Acyl-coenzyme A oxidase 3, peroxisomal (EC 1.3.3.6) (Pristanoyl-CoA oxidase) (Branched-chain acyl-CoA oxidase) (BRCACox).

JHD2C_MOUSE
NC score	0.013922 (rank : 78)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	297	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

GP158_HUMAN
NC score	0.012730 (rank : 79)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	221	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

DYNA_HUMAN
NC score	0.012071 (rank : 80)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	1194	Shared Neighborhood Hits	13
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

COA1_HUMAN
NC score	0.010715 (rank : 81)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q13085	Gene names	ACACA, ACAC, ACC1, ACCA
Domain Architecture
Description	Acetyl-CoA carboxylase 1 (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)].

RHG26_HUMAN
NC score	0.009867 (rank : 82)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

SFRS4_MOUSE
NC score	0.009242 (rank : 83)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	406	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

CCD46_MOUSE
NC score	0.008348 (rank : 84)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	1405	Shared Neighborhood Hits	13
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CNGA1_HUMAN
NC score	0.006397 (rank : 85)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	149	Shared Neighborhood Hits	4
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

ANK3_HUMAN
NC score	0.004192 (rank : 86)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	853	Shared Neighborhood Hits	11
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ROCK1_HUMAN
NC score	0.002191 (rank : 87)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	2000	Shared Neighborhood Hits	11
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK1_MOUSE
NC score	0.001999 (rank : 88)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	2126	Shared Neighborhood Hits	13
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).