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Network neighborhood for query Sequence : IMA2_HUMAN

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IMA2_HUMAN
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IMA2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
θ value	0 (rank : 2)	NC score	0.998158 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	38
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA4_MOUSE
θ value	3.62588e-142 (rank : 3)	NC score	0.975346 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	27
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA4_HUMAN
θ value	6.18479e-142 (rank : 4)	NC score	0.975606 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA3_HUMAN
θ value	3.06949e-141 (rank : 5)	NC score	0.976332 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA3_MOUSE
θ value	4.00889e-141 (rank : 6)	NC score	0.975883 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA5_HUMAN
θ value	3.64273e-126 (rank : 7)	NC score	0.972242 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA7_HUMAN
θ value	3.76964e-123 (rank : 8)	NC score	0.969051 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA7_MOUSE
θ value	5.44333e-122 (rank : 9)	NC score	0.968150 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA1_HUMAN
θ value	1.75107e-120 (rank : 10)	NC score	0.970630 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
θ value	5.09482e-120 (rank : 11)	NC score	0.970130 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

SPAG6_MOUSE
θ value	3.18553e-13 (rank : 12)	NC score	0.632302 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	62	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

SPAG6_HUMAN
θ value	1.02475e-11 (rank : 13)	NC score	0.634055 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

ARMC4_HUMAN
θ value	1.17247e-07 (rank : 14)	NC score	0.327542 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CTNB1_HUMAN
θ value	4.45536e-07 (rank : 15)	NC score	0.249487 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_MOUSE
θ value	4.45536e-07 (rank : 16)	NC score	0.249530 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
θ value	2.88788e-06 (rank : 17)	NC score	0.236423 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	55	Shared Neighborhood Hits	24
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_HUMAN
θ value	1.87187e-05 (rank : 18)	NC score	0.204660 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

TRIPC_HUMAN
θ value	0.00035302 (rank : 19)	NC score	0.119385 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	319	Shared Neighborhood Hits	10
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

GDS1_HUMAN
θ value	0.000461057 (rank : 20)	NC score	0.319884 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	26
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

PKP4_HUMAN
θ value	0.00175202 (rank : 21)	NC score	0.168865 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

PKP4_MOUSE
θ value	0.00175202 (rank : 22)	NC score	0.169700 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PSMD5_MOUSE
θ value	0.0252991 (rank : 23)	NC score	0.081679 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BJY1, Q3UFV2, Q8BMA9, Q8VEE9	Gene names	Psmd5
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 5 (26S proteasome subunit S5B) (26S protease subunit S5 basic).

PSMD5_HUMAN
θ value	0.0736092 (rank : 24)	NC score	0.075382 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q16401, Q15045	Gene names	PSMD5, KIAA0072
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 5 (26S proteasome subunit S5B) (26S protease subunit S5 basic).

LRRK2_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.008754 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	1382	Shared Neighborhood Hits	8
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

CTND2_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.134538 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	333	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

CTND2_MOUSE
θ value	0.47712 (rank : 27)	NC score	0.134990 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CTND1_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.120144 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

LRRK2_MOUSE
θ value	0.813845 (rank : 29)	NC score	0.010902 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	1359	Shared Neighborhood Hits	9
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

CTND1_HUMAN
θ value	1.06291 (rank : 30)	NC score	0.112957 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

LRC47_MOUSE
θ value	1.06291 (rank : 31)	NC score	0.010966 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	299	Shared Neighborhood Hits	4
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

IPO4_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.016441 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

SLC2B_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.021955 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	214	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

TRXR2_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.012717 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NNW7, O95840, Q96IJ2, Q9H2Z5, Q9NZV3, Q9NZV4, Q9P2Y0, Q9P2Y1, Q9UQU8	Gene names	TXNRD2, TRXR2
Domain Architecture
Description	Thioredoxin reductase 2, mitochondrial precursor (EC 1.8.1.9) (TR3) (TR-beta) (Selenoprotein Z) (SelZ).

ARVC_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.118543 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

CENPI_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.022543 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1K4, Q8BXU9	Gene names	Cenpi, Fshprh1
Domain Architecture	No domain graphic available
Description	Centromere protein I (CENP-I) (Follicle-stimulating hormone primary response protein) (FSH primary response protein 1).

SETD2_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.015430 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	412	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

STK39_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.001287 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	882	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

STK39_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.001261 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	915	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

ARVC_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.119180 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	95	Shared Neighborhood Hits	25
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ARMC6_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.051480 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4	Gene names	Armc6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

ECEL1_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.006312 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JMI0	Gene names	Ecel1, Dine, Xce
Domain Architecture
Description	Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein) (Damage-induced neuronal endopeptidase).

RASA2_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.015029 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

LETM1_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.008241 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

FBX41_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.008609 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	475	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

FBX41_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.008777 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	430	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

TAP1_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.002392 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

UN45A_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.049363 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

DSRAD_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.008899 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

FMNL_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.002429 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	529	Shared Neighborhood Hits	2
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

TTC14_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.006972 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	274	Shared Neighborhood Hits	3
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

GCN1L_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.056067 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	112	Shared Neighborhood Hits	10
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

IMB1_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.067332 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

PKP1_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.060541 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP1_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.059903 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP3_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.058910 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

PKP3_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.055977 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

RL35_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.087195 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P42766, Q4VBY5, Q5JTN5, Q6IBC7, Q96QJ7, Q9BYF4	Gene names	RPL35
Domain Architecture	No domain graphic available
Description	60S ribosomal protein L35.

SARM1_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.065020 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

SARM1_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.065893 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

TNPO1_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.060912 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	64	Shared Neighborhood Hits	8
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.056676 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

Hits sorted by NC score

IMA2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
NC score	0.998158 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	38
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA3_HUMAN
NC score	0.976332 (rank : 3)	θ value	3.06949e-141 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA3_MOUSE
NC score	0.975883 (rank : 4)	θ value	4.00889e-141 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA4_HUMAN
NC score	0.975606 (rank : 5)	θ value	6.18479e-142 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA4_MOUSE
NC score	0.975346 (rank : 6)	θ value	3.62588e-142 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	27
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA5_HUMAN
NC score	0.972242 (rank : 7)	θ value	3.64273e-126 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	68	Shared Neighborhood Hits	29
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IMA1_HUMAN
NC score	0.970630 (rank : 8)	θ value	1.75107e-120 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	26
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
NC score	0.970130 (rank : 9)	θ value	5.09482e-120 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

IMA7_HUMAN
NC score	0.969051 (rank : 10)	θ value	3.76964e-123 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA7_MOUSE
NC score	0.968150 (rank : 11)	θ value	5.44333e-122 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

SPAG6_HUMAN
NC score	0.634055 (rank : 12)	θ value	1.02475e-11 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	24
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

SPAG6_MOUSE
NC score	0.632302 (rank : 13)	θ value	3.18553e-13 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	62	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

ARMC4_HUMAN
NC score	0.327542 (rank : 14)	θ value	1.17247e-07 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	88	Shared Neighborhood Hits	29
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

GDS1_HUMAN
NC score	0.319884 (rank : 15)	θ value	0.000461057 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	26
SwissProt Accessions	P52306, Q9NYM2, Q9NZA8	Gene names	RAP1GDS1
Domain Architecture
Description	Rap1 GTPase-GDP dissociation stimulator 1 (SMG P21 stimulatory GDP/GTP exchange protein) (SMG GDS protein) (Exchange factor smgGDS).

CTNB1_MOUSE
NC score	0.249530 (rank : 16)	θ value	4.45536e-07 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q02248, Q922W1, Q9D335	Gene names	Ctnnb1, Catnb
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

CTNB1_HUMAN
NC score	0.249487 (rank : 17)	θ value	4.45536e-07 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	P35222, Q8NEW9, Q8NI94, Q9H391	Gene names	CTNNB1, CTNNB
Domain Architecture
Description	Catenin beta-1 (Beta-catenin).

PLAK_MOUSE
NC score	0.236423 (rank : 18)	θ value	2.88788e-06 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	55	Shared Neighborhood Hits	24
SwissProt Accessions	Q02257, Q8CGD3	Gene names	Jup
Domain Architecture	No domain graphic available
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PLAK_HUMAN
NC score	0.204660 (rank : 19)	θ value	1.87187e-05 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	P14923, Q9HCX9	Gene names	JUP, DP3
Domain Architecture
Description	Junction plakoglobin (Desmoplakin-3) (Desmoplakin III).

PKP4_MOUSE
NC score	0.169700 (rank : 20)	θ value	0.00175202 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

PKP4_HUMAN
NC score	0.168865 (rank : 21)	θ value	0.00175202 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q99569	Gene names	PKP4
Domain Architecture
Description	Plakophilin-4 (p0071).

CTND2_MOUSE
NC score	0.134990 (rank : 22)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	O35927	Gene names	Ctnnd2, Catnd2, Nprap
Domain Architecture
Description	Catenin delta-2 (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin).

CTND2_HUMAN
NC score	0.134538 (rank : 23)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	333	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UQB3, O00379, O15390, O43206, O43840, Q13589, Q9UM66, Q9UPM3	Gene names	CTNND2, NPRAP
Domain Architecture
Description	Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24).

CTND1_MOUSE
NC score	0.120144 (rank : 24)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	P30999	Gene names	Ctnnd1, Catns
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

TRIPC_HUMAN
NC score	0.119385 (rank : 25)	θ value	0.00035302 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	319	Shared Neighborhood Hits	10
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

ARVC_HUMAN
NC score	0.119180 (rank : 26)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	95	Shared Neighborhood Hits	25
SwissProt Accessions	O00192	Gene names	ARVCF
Domain Architecture
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome.

ARVC_MOUSE
NC score	0.118543 (rank : 27)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	P98203, Q6PGJ6, Q8BQ36, Q8BRF2, Q8C3U7, Q924L2, Q924L3, Q924L4, Q924L5	Gene names	Arvcf
Domain Architecture	No domain graphic available
Description	Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog.

CTND1_HUMAN
NC score	0.112957 (rank : 28)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73	Gene names	CTNND1, KIAA0384
Domain Architecture
Description	Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).

RL35_HUMAN
NC score	0.087195 (rank : 29)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	P42766, Q4VBY5, Q5JTN5, Q6IBC7, Q96QJ7, Q9BYF4	Gene names	RPL35
Domain Architecture	No domain graphic available
Description	60S ribosomal protein L35.

PSMD5_MOUSE
NC score	0.081679 (rank : 30)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BJY1, Q3UFV2, Q8BMA9, Q8VEE9	Gene names	Psmd5
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 5 (26S proteasome subunit S5B) (26S protease subunit S5 basic).

PSMD5_HUMAN
NC score	0.075382 (rank : 31)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q16401, Q15045	Gene names	PSMD5, KIAA0072
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 5 (26S proteasome subunit S5B) (26S protease subunit S5 basic).

IMB1_MOUSE
NC score	0.067332 (rank : 32)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

SARM1_MOUSE
NC score	0.065893 (rank : 33)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

SARM1_HUMAN
NC score	0.065020 (rank : 34)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q6SZW1, O60277, Q7LGG3, Q9NXY5	Gene names	SARM1, KIAA0524, SARM
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Tir-1 homolog).

TNPO1_HUMAN
NC score	0.060912 (rank : 35)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	64	Shared Neighborhood Hits	8
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

PKP1_HUMAN
NC score	0.060541 (rank : 36)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	Q13835, O00645, Q15152	Gene names	PKP1
Domain Architecture
Description	Plakophilin-1 (Band-6 protein) (B6P).

PKP1_MOUSE
NC score	0.059903 (rank : 37)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	16
SwissProt Accessions	P97350	Gene names	Pkp1
Domain Architecture
Description	Plakophilin-1.

PKP3_HUMAN
NC score	0.058910 (rank : 38)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y446	Gene names	PKP3
Domain Architecture
Description	Plakophilin-3.

TNPO1_MOUSE
NC score	0.056676 (rank : 39)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

GCN1L_HUMAN
NC score	0.056067 (rank : 40)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	112	Shared Neighborhood Hits	10
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

PKP3_MOUSE
NC score	0.055977 (rank : 41)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

ARMC6_MOUSE
NC score	0.051480 (rank : 42)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BNU0, Q8C4P5, Q8C7S1, Q8K2S7, Q99JQ2, Q9CWE4	Gene names	Armc6
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 6.

UN45A_HUMAN
NC score	0.049363 (rank : 43)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	122	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

CENPI_MOUSE
NC score	0.022543 (rank : 44)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1K4, Q8BXU9	Gene names	Cenpi, Fshprh1
Domain Architecture	No domain graphic available
Description	Centromere protein I (CENP-I) (Follicle-stimulating hormone primary response protein) (FSH primary response protein 1).

SLC2B_HUMAN
NC score	0.021955 (rank : 45)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	214	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

IPO4_MOUSE
NC score	0.016441 (rank : 46)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

SETD2_HUMAN
NC score	0.015430 (rank : 47)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	412	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

RASA2_HUMAN
NC score	0.015029 (rank : 48)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

TRXR2_HUMAN
NC score	0.012717 (rank : 49)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NNW7, O95840, Q96IJ2, Q9H2Z5, Q9NZV3, Q9NZV4, Q9P2Y0, Q9P2Y1, Q9UQU8	Gene names	TXNRD2, TRXR2
Domain Architecture
Description	Thioredoxin reductase 2, mitochondrial precursor (EC 1.8.1.9) (TR3) (TR-beta) (Selenoprotein Z) (SelZ).

LRC47_MOUSE
NC score	0.010966 (rank : 50)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	299	Shared Neighborhood Hits	4
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

LRRK2_MOUSE
NC score	0.010902 (rank : 51)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	1359	Shared Neighborhood Hits	9
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

DSRAD_HUMAN
NC score	0.008899 (rank : 52)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

FBX41_MOUSE
NC score	0.008777 (rank : 53)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	430	Shared Neighborhood Hits	3
SwissProt Accessions	Q6NS60, Q6P7W4, Q6ZPG1	Gene names	Fbxo41, D6Ertd538e, Kiaa1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

LRRK2_HUMAN
NC score	0.008754 (rank : 54)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	1382	Shared Neighborhood Hits	8
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

FBX41_HUMAN
NC score	0.008609 (rank : 55)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	475	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TF61	Gene names	FBXO41, FBX41, KIAA1940
Domain Architecture	No domain graphic available
Description	F-box only protein 41.

LETM1_MOUSE
NC score	0.008241 (rank : 56)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

TTC14_HUMAN
NC score	0.006972 (rank : 57)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	274	Shared Neighborhood Hits	3
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

ECEL1_MOUSE
NC score	0.006312 (rank : 58)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JMI0	Gene names	Ecel1, Dine, Xce
Domain Architecture
Description	Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein) (Damage-induced neuronal endopeptidase).

FMNL_HUMAN
NC score	0.002429 (rank : 59)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	529	Shared Neighborhood Hits	2
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

TAP1_MOUSE
NC score	0.002392 (rank : 60)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	95	Shared Neighborhood Hits	2
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

STK39_HUMAN
NC score	0.001287 (rank : 61)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	882	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

STK39_MOUSE
NC score	0.001261 (rank : 62)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	915	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).