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Network neighborhood for query Sequence : IMB1_MOUSE

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IMB1_MOUSE
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IMB1_HUMAN
θ value	0 (rank : 1)	NC score	0.997809 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

IMB1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

TNPO1_MOUSE
θ value	3.07116e-24 (rank : 3)	NC score	0.629321 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	63	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO2_MOUSE
θ value	6.84181e-24 (rank : 4)	NC score	0.626081 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO1_HUMAN
θ value	8.93572e-24 (rank : 5)	NC score	0.627292 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO2_HUMAN
θ value	5.79196e-23 (rank : 6)	NC score	0.621484 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

IMB3_MOUSE
θ value	2.36244e-08 (rank : 7)	NC score	0.391179 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_HUMAN
θ value	4.0297e-08 (rank : 8)	NC score	0.388715 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

RNBP6_HUMAN
θ value	7.1131e-05 (rank : 9)	NC score	0.358231 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

IPO4_MOUSE
θ value	0.000121331 (rank : 10)	NC score	0.309640 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	44	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

2AAA_MOUSE
θ value	0.00298849 (rank : 11)	NC score	0.184466 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	15
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAB_MOUSE
θ value	0.00390308 (rank : 12)	NC score	0.179559 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAA_HUMAN
θ value	0.0113563 (rank : 13)	NC score	0.174314 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

IMA7_HUMAN
θ value	0.0113563 (rank : 14)	NC score	0.141444 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

FRAP_HUMAN
θ value	0.0148317 (rank : 15)	NC score	0.116116 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	83	Shared Neighborhood Hits	17
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_MOUSE
θ value	0.0148317 (rank : 16)	NC score	0.115158 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	77	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

IMA5_HUMAN
θ value	0.0148317 (rank : 17)	NC score	0.127826 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

IPO4_HUMAN
θ value	0.0148317 (rank : 18)	NC score	0.292007 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	49	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

DOCK3_MOUSE
θ value	0.0252991 (rank : 19)	NC score	0.064554 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

2AAB_HUMAN
θ value	0.0563607 (rank : 20)	NC score	0.161741 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

IMA7_MOUSE
θ value	0.0961366 (rank : 21)	NC score	0.130499 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

DOCK3_HUMAN
θ value	0.279714 (rank : 22)	NC score	0.054425 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

IMA1_HUMAN
θ value	0.365318 (rank : 23)	NC score	0.088860 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	9
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

IMA1_MOUSE
θ value	0.365318 (rank : 24)	NC score	0.092956 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

P3H2_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.038579 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IVL5, Q9NVI2	Gene names	LEPREL1, MLAT4, P3H2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4).

S3TC2_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.038791 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

IMA4_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.100625 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

GCN1L_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.110166 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	112	Shared Neighborhood Hits	24
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

IMA4_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.098862 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	16
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IF2P_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.015548 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	889	Shared Neighborhood Hits	4
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

SLIT2_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.009970 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	684	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SMG1_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.043018 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

P3H2_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.029882 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG71, Q8C673	Gene names	Leprel1, P3h2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1).

RTDR1_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.071448 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

SLIT2_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.009399 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	708	Shared Neighborhood Hits	5
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SPAG6_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.087818 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

WDR17_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.012569 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	335	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

CAND2_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.059840 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	40	Shared Neighborhood Hits	18
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

ESCO1_MOUSE
θ value	5.27518 (rank : 39)	NC score	0.022860 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

K2C1B_HUMAN
θ value	5.27518 (rank : 40)	NC score	0.005209 (rank : 64)
Query Neighborhood Hits	51	Target Neighborhood Hits	542	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

PCNT_HUMAN
θ value	5.27518 (rank : 41)	NC score	0.006628 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	1551	Shared Neighborhood Hits	6
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CAND1_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.040439 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CAND1_MOUSE
θ value	6.88961 (rank : 43)	NC score	0.032274 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

TEX15_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.017466 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

TRI16_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.012784 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	231	Shared Neighborhood Hits	3
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

XPO2_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.092219 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	P55060, O75432, Q32M40, Q9H5B7, Q9NTS0, Q9UP98, Q9UP99, Q9UPA0	Gene names	CSE1L, CAS, XPO2
Domain Architecture
Description	Exportin-2 (Exp2) (Importin-alpha re-exporter) (Chromosome segregation 1-like protein) (Cellular apoptosis susceptibility protein).

XPO2_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.090900 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ERK4	Gene names	Cse1l, Xpo2
Domain Architecture
Description	Exportin-2 (Exp2) (Importin-alpha re-exporter) (Chromosome segregation 1-like protein).

ABCAD_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.006269 (rank : 63)
Query Neighborhood Hits	51	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ARP5_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.012580 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q80US4, Q8BL26	Gene names	Actr5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5.

FYV1_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.011205 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

RXFP2_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.002927 (rank : 65)
Query Neighborhood Hits	51	Target Neighborhood Hits	760	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

ECM29_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.050635 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VYK3, O15074, Q8WU82	Gene names	ECM29, KIAA0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

ECM29_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.051111 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	65	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

HEAT2_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.055184 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

IMA2_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.067332 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.066534 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

IMA3_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.079881 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IMA3_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.085028 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	13
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IPO11_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.073413 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UI26, Q8N5R2, Q9NSJ6, Q9NVB1	Gene names	IPO11, RANBP11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

IPO11_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.074115 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K2V6, Q8BU45, Q8K0B4	Gene names	Ipo11, Ranbp11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

IPO9_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.064010 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q96P70, Q8N1Y1, Q8N3I2, Q8NCG9, Q96SU6, Q9NW01, Q9P0A8, Q9ULM8	Gene names	IPO9, IMP9, KIAA1192, RANBP9
Domain Architecture
Description	Importin-9 (Imp9) (Ran-binding protein 9) (RanbP9).

IPO9_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.063692 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q91YE6, Q924M3, Q924M4	Gene names	Ipo9, Imp9, Ranbp9
Domain Architecture
Description	Importin-9 (Importin 9a) (Imp9a) (Importin 9b) (Imp9b) (Ran-binding protein 9) (RanBP9).

PMF1_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.064782 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CPV5, Q3UCB8, Q8K237, Q924B3, Q9D6E2	Gene names	Pmf1
Domain Architecture	No domain graphic available
Description	Polyamine-modulated factor 1 (PMF-1).

PP4RL_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.053470 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

SPAG6_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.073266 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

Hits sorted by NC score

IMB1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

IMB1_HUMAN
NC score	0.997809 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	46
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

TNPO1_MOUSE
NC score	0.629321 (rank : 3)	θ value	3.07116e-24 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	63	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO1_HUMAN
NC score	0.627292 (rank : 4)	θ value	8.93572e-24 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO2_MOUSE
NC score	0.626081 (rank : 5)	θ value	6.84181e-24 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_HUMAN
NC score	0.621484 (rank : 6)	θ value	5.79196e-23 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

IMB3_MOUSE
NC score	0.391179 (rank : 7)	θ value	2.36244e-08 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_HUMAN
NC score	0.388715 (rank : 8)	θ value	4.0297e-08 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	20
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

RNBP6_HUMAN
NC score	0.358231 (rank : 9)	θ value	7.1131e-05 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

IPO4_MOUSE
NC score	0.309640 (rank : 10)	θ value	0.000121331 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	44	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

IPO4_HUMAN
NC score	0.292007 (rank : 11)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	49	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

2AAA_MOUSE
NC score	0.184466 (rank : 12)	θ value	0.00298849 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	15
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAB_MOUSE
NC score	0.179559 (rank : 13)	θ value	0.00390308 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAA_HUMAN
NC score	0.174314 (rank : 14)	θ value	0.0113563 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAB_HUMAN
NC score	0.161741 (rank : 15)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

IMA7_HUMAN
NC score	0.141444 (rank : 16)	θ value	0.0113563 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	O60684	Gene names	KPNA6, IPOA7
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6).

IMA7_MOUSE
NC score	0.130499 (rank : 17)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	O35345, Q9CVP9	Gene names	Kpna6, Kpna5
Domain Architecture
Description	Importin alpha-7 subunit (Karyopherin alpha-6 subunit) (Importin alpha S2).

IMA5_HUMAN
NC score	0.127826 (rank : 18)	θ value	0.0148317 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

FRAP_HUMAN
NC score	0.116116 (rank : 19)	θ value	0.0148317 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	83	Shared Neighborhood Hits	17
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_MOUSE
NC score	0.115158 (rank : 20)	θ value	0.0148317 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	77	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

GCN1L_HUMAN
NC score	0.110166 (rank : 21)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	112	Shared Neighborhood Hits	24
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

IMA4_MOUSE
NC score	0.100625 (rank : 22)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	O35343	Gene names	Kpna4
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Importin alpha Q1).

IMA4_HUMAN
NC score	0.098862 (rank : 23)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	16
SwissProt Accessions	O00629, O00190	Gene names	KPNA4, QIP1
Domain Architecture
Description	Importin alpha-4 subunit (Karyopherin alpha-4 subunit) (Qip1 protein).

IMA1_MOUSE
NC score	0.092956 (rank : 24)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q60960, Q3TF32	Gene names	Kpna1, Rch2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (Importin alpha S1).

XPO2_HUMAN
NC score	0.092219 (rank : 25)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	P55060, O75432, Q32M40, Q9H5B7, Q9NTS0, Q9UP98, Q9UP99, Q9UPA0	Gene names	CSE1L, CAS, XPO2
Domain Architecture
Description	Exportin-2 (Exp2) (Importin-alpha re-exporter) (Chromosome segregation 1-like protein) (Cellular apoptosis susceptibility protein).

XPO2_MOUSE
NC score	0.090900 (rank : 26)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	27	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ERK4	Gene names	Cse1l, Xpo2
Domain Architecture
Description	Exportin-2 (Exp2) (Importin-alpha re-exporter) (Chromosome segregation 1-like protein).

IMA1_HUMAN
NC score	0.088860 (rank : 27)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	9
SwissProt Accessions	P52294, Q9BQ56	Gene names	KPNA1, RCH2
Domain Architecture
Description	Importin alpha-1 subunit (Karyopherin alpha-1 subunit) (SRP1-beta) (RAG cohort protein 2) (Nucleoprotein interactor 1) (NPI-1).

SPAG6_MOUSE
NC score	0.087818 (rank : 28)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	62	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JLI7, Q8K461	Gene names	Spag6, Pf16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Axoneme central apparatus protein).

IMA3_MOUSE
NC score	0.085028 (rank : 29)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	13
SwissProt Accessions	O35344	Gene names	Kpna3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (Importin alpha Q2).

IMA3_HUMAN
NC score	0.079881 (rank : 30)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	O00505, O00191, O43195, Q96AA7	Gene names	KPNA3
Domain Architecture
Description	Importin alpha-3 subunit (Karyopherin alpha-3 subunit) (SRP1-gamma).

IPO11_MOUSE
NC score	0.074115 (rank : 31)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K2V6, Q8BU45, Q8K0B4	Gene names	Ipo11, Ranbp11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

IPO11_HUMAN
NC score	0.073413 (rank : 32)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UI26, Q8N5R2, Q9NSJ6, Q9NVB1	Gene names	IPO11, RANBP11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

SPAG6_HUMAN
NC score	0.073266 (rank : 33)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	O75602, Q5VUX5, Q5VUX6, Q5VUX7, Q6FI74, Q8NHQ6	Gene names	SPAG6, PF16
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 6 (PF16 protein homolog) (Sperm flagellar protein) (Repro-SA-1).

RTDR1_HUMAN
NC score	0.071448 (rank : 34)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

IMA2_HUMAN
NC score	0.067332 (rank : 35)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	9
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

IMA2_MOUSE
NC score	0.066534 (rank : 36)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	P52293, Q64292	Gene names	Kpna2, Rch1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1) (Pendulin) (Pore targeting complex 58 kDa subunit) (PTAC58) (Importin alpha P1).

PMF1_MOUSE
NC score	0.064782 (rank : 37)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	51	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CPV5, Q3UCB8, Q8K237, Q924B3, Q9D6E2	Gene names	Pmf1
Domain Architecture	No domain graphic available
Description	Polyamine-modulated factor 1 (PMF-1).

DOCK3_MOUSE
NC score	0.064554 (rank : 38)	θ value	0.0252991 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIQ7	Gene names	Dock3, Moca
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

IPO9_HUMAN
NC score	0.064010 (rank : 39)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q96P70, Q8N1Y1, Q8N3I2, Q8NCG9, Q96SU6, Q9NW01, Q9P0A8, Q9ULM8	Gene names	IPO9, IMP9, KIAA1192, RANBP9
Domain Architecture
Description	Importin-9 (Imp9) (Ran-binding protein 9) (RanbP9).

IPO9_MOUSE
NC score	0.063692 (rank : 40)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q91YE6, Q924M3, Q924M4	Gene names	Ipo9, Imp9, Ranbp9
Domain Architecture
Description	Importin-9 (Importin 9a) (Imp9a) (Importin 9b) (Imp9b) (Ran-binding protein 9) (RanBP9).

CAND2_HUMAN
NC score	0.059840 (rank : 41)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	40	Shared Neighborhood Hits	18
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

HEAT2_HUMAN
NC score	0.055184 (rank : 42)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

DOCK3_HUMAN
NC score	0.054425 (rank : 43)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

PP4RL_HUMAN
NC score	0.053470 (rank : 44)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	51	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

ECM29_MOUSE
NC score	0.051111 (rank : 45)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	65	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

ECM29_HUMAN
NC score	0.050635 (rank : 46)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VYK3, O15074, Q8WU82	Gene names	ECM29, KIAA0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

SMG1_MOUSE
NC score	0.043018 (rank : 47)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

CAND1_HUMAN
NC score	0.040439 (rank : 48)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

S3TC2_MOUSE
NC score	0.038791 (rank : 49)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

P3H2_HUMAN
NC score	0.038579 (rank : 50)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IVL5, Q9NVI2	Gene names	LEPREL1, MLAT4, P3H2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4).

CAND1_MOUSE
NC score	0.032274 (rank : 51)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

P3H2_MOUSE
NC score	0.029882 (rank : 52)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CG71, Q8C673	Gene names	Leprel1, P3h2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1).

ESCO1_MOUSE
NC score	0.022860 (rank : 53)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

TEX15_HUMAN
NC score	0.017466 (rank : 54)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

IF2P_HUMAN
NC score	0.015548 (rank : 55)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	889	Shared Neighborhood Hits	4
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

TRI16_HUMAN
NC score	0.012784 (rank : 56)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	231	Shared Neighborhood Hits	3
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

ARP5_MOUSE
NC score	0.012580 (rank : 57)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q80US4, Q8BL26	Gene names	Actr5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5.

WDR17_HUMAN
NC score	0.012569 (rank : 58)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	335	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZU2	Gene names	WDR17
Domain Architecture
Description	WD repeat protein 17.

FYV1_MOUSE
NC score	0.011205 (rank : 59)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

SLIT2_MOUSE
NC score	0.009970 (rank : 60)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	684	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_HUMAN
NC score	0.009399 (rank : 61)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	708	Shared Neighborhood Hits	5
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

PCNT_HUMAN
NC score	0.006628 (rank : 62)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	1551	Shared Neighborhood Hits	6
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

ABCAD_HUMAN
NC score	0.006269 (rank : 63)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

K2C1B_HUMAN
NC score	0.005209 (rank : 64)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	542	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

RXFP2_MOUSE
NC score	0.002927 (rank : 65)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	760	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).