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Network neighborhood for query Sequence : CAND2_HUMAN

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CAND2_HUMAN
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAND1_HUMAN
θ value	0 (rank : 1)	NC score	0.980566 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CAND1_MOUSE
θ value	0 (rank : 2)	NC score	0.980509 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

CAND2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

CAND2_MOUSE
θ value	0 (rank : 4)	NC score	0.992498 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

IPO4_HUMAN
θ value	9.92553e-07 (rank : 5)	NC score	0.233366 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	49	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

IPO4_MOUSE
θ value	9.29e-05 (rank : 6)	NC score	0.195599 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

FRAP_MOUSE
θ value	0.00102713 (rank : 7)	NC score	0.109508 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	77	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
θ value	0.00134147 (rank : 8)	NC score	0.109219 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	83	Shared Neighborhood Hits	15
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

2AAA_HUMAN
θ value	0.0431538 (rank : 9)	NC score	0.081144 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
θ value	0.0961366 (rank : 10)	NC score	0.079142 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	15
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

KIFC2_HUMAN
θ value	0.279714 (rank : 11)	NC score	0.017946 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	237	Shared Neighborhood Hits	5
SwissProt Accessions	Q96AC6	Gene names	KIFC2
Domain Architecture
Description	Kinesin-like protein KIFC2.

CLAP2_HUMAN
θ value	0.365318 (rank : 12)	NC score	0.088557 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	O75122, Q7L8F6, Q8N6R6, Q9BQT3, Q9BQT4, Q9H7A3, Q9NSZ2	Gene names	CLASP2, KIAA0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

CLAP2_MOUSE
θ value	0.365318 (rank : 13)	NC score	0.089139 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

IMB3_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.108486 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	57	Shared Neighborhood Hits	18
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

GCN1L_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.155618 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	112	Shared Neighborhood Hits	21
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

IMB3_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.103943 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

TNPO2_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.060358 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.060680 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

KCNK7_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.018545 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

COPG_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.033298 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y678	Gene names	COPG
Domain Architecture
Description	Coatomer subunit gamma (Gamma-coat protein) (Gamma-COP).

KIF1A_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.011307 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	240	Shared Neighborhood Hits	5
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

SF3B1_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.056283 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	341	Shared Neighborhood Hits	16
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.047025 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SOX30_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.010362 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	374	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

FA5_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.008843 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	172	Shared Neighborhood Hits	2
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

TPO_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.026814 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P40225, Q13020, Q15790, Q15791, Q15792	Gene names	THPO
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

COPG2_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.029043 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBF2	Gene names	COPG2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

IMB1_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.059840 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

COPG2_MOUSE
θ value	6.88961 (rank : 29)	NC score	0.027134 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

TGM5_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.005715 (rank : 42)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7I9, Q3V1F9	Gene names	Tgm5
Domain Architecture	No domain graphic available
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5).

TNPO1_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.057725 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.057698 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TPO_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.018945 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	258	Shared Neighborhood Hits	3
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

UBR2_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.016982 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

IMB1_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.057607 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

K0423_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.012213 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

KCNK7_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.013492 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KIF1A_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.009824 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	239	Shared Neighborhood Hits	5
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KIF1B_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.009423 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q60575, Q9R0B4, Q9WVE5, Q9Z119	Gene names	Kif1b
Domain Architecture
Description	Kinesin-like protein KIF1B.

UTP20_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.015512 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

CLAP1_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.055586 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z460, O75118, Q8N5B8, Q9BQT5	Gene names	CLASP1, KIAA0622, MAST1
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1).

RNBP6_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.059482 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

Hits sorted by NC score

CAND2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

CAND2_MOUSE
NC score	0.992498 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

CAND1_HUMAN
NC score	0.980566 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CAND1_MOUSE
NC score	0.980509 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

IPO4_HUMAN
NC score	0.233366 (rank : 5)	θ value	9.92553e-07 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	49	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

IPO4_MOUSE
NC score	0.195599 (rank : 6)	θ value	9.29e-05 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

GCN1L_HUMAN
NC score	0.155618 (rank : 7)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	112	Shared Neighborhood Hits	21
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

FRAP_MOUSE
NC score	0.109508 (rank : 8)	θ value	0.00102713 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	77	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
NC score	0.109219 (rank : 9)	θ value	0.00134147 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	83	Shared Neighborhood Hits	15
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

IMB3_HUMAN
NC score	0.108486 (rank : 10)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	57	Shared Neighborhood Hits	18
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_MOUSE
NC score	0.103943 (rank : 11)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

CLAP2_MOUSE
NC score	0.089139 (rank : 12)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

CLAP2_HUMAN
NC score	0.088557 (rank : 13)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	O75122, Q7L8F6, Q8N6R6, Q9BQT3, Q9BQT4, Q9H7A3, Q9NSZ2	Gene names	CLASP2, KIAA0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

2AAA_HUMAN
NC score	0.081144 (rank : 14)	θ value	0.0431538 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
NC score	0.079142 (rank : 15)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	15
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

TNPO2_MOUSE
NC score	0.060680 (rank : 16)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_HUMAN
NC score	0.060358 (rank : 17)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

IMB1_MOUSE
NC score	0.059840 (rank : 18)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

RNBP6_HUMAN
NC score	0.059482 (rank : 19)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	40	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

TNPO1_HUMAN
NC score	0.057725 (rank : 20)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
NC score	0.057698 (rank : 21)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

IMB1_HUMAN
NC score	0.057607 (rank : 22)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

SF3B1_HUMAN
NC score	0.056283 (rank : 23)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	341	Shared Neighborhood Hits	16
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

CLAP1_HUMAN
NC score	0.055586 (rank : 24)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z460, O75118, Q8N5B8, Q9BQT5	Gene names	CLASP1, KIAA0622, MAST1
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1).

SF3B1_MOUSE
NC score	0.047025 (rank : 25)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

COPG_HUMAN
NC score	0.033298 (rank : 26)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y678	Gene names	COPG
Domain Architecture
Description	Coatomer subunit gamma (Gamma-coat protein) (Gamma-COP).

COPG2_HUMAN
NC score	0.029043 (rank : 27)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBF2	Gene names	COPG2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

COPG2_MOUSE
NC score	0.027134 (rank : 28)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

TPO_HUMAN
NC score	0.026814 (rank : 29)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P40225, Q13020, Q15790, Q15791, Q15792	Gene names	THPO
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TPO_MOUSE
NC score	0.018945 (rank : 30)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	258	Shared Neighborhood Hits	3
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

KCNK7_MOUSE
NC score	0.018545 (rank : 31)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KIFC2_HUMAN
NC score	0.017946 (rank : 32)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	237	Shared Neighborhood Hits	5
SwissProt Accessions	Q96AC6	Gene names	KIFC2
Domain Architecture
Description	Kinesin-like protein KIFC2.

UBR2_MOUSE
NC score	0.016982 (rank : 33)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

UTP20_HUMAN
NC score	0.015512 (rank : 34)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

KCNK7_HUMAN
NC score	0.013492 (rank : 35)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

K0423_MOUSE
NC score	0.012213 (rank : 36)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	115	Shared Neighborhood Hits	7
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

KIF1A_HUMAN
NC score	0.011307 (rank : 37)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	240	Shared Neighborhood Hits	5
SwissProt Accessions	Q12756	Gene names	KIF1A, ATSV
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

SOX30_MOUSE
NC score	0.010362 (rank : 38)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	374	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

KIF1A_MOUSE
NC score	0.009824 (rank : 39)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	239	Shared Neighborhood Hits	5
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

KIF1B_MOUSE
NC score	0.009423 (rank : 40)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	167	Shared Neighborhood Hits	5
SwissProt Accessions	Q60575, Q9R0B4, Q9WVE5, Q9Z119	Gene names	Kif1b
Domain Architecture
Description	Kinesin-like protein KIF1B.

FA5_HUMAN
NC score	0.008843 (rank : 41)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	172	Shared Neighborhood Hits	2
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

TGM5_MOUSE
NC score	0.005715 (rank : 42)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D7I9, Q3V1F9	Gene names	Tgm5
Domain Architecture	No domain graphic available
Description	Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase-5) (TGase 5).