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Network neighborhood for query Sequence : TPO_HUMAN

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TPO_HUMAN
SwissProt Accessions	P40225, Q13020, Q15790, Q15791, Q15792	Gene names	THPO
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TPO_HUMAN
θ value	2.76981e-150 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P40225, Q13020, Q15790, Q15791, Q15792	Gene names	THPO
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TPO_MOUSE
θ value	1.59483e-97 (rank : 2)	NC score	0.818149 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	258	Shared Neighborhood Hits	8
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

NCOA5_MOUSE
θ value	0.0330416 (rank : 3)	NC score	0.135370 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W39	Gene names	Ncoa5
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

EPO_MOUSE
θ value	0.0563607 (rank : 4)	NC score	0.167642 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P07321	Gene names	Epo
Domain Architecture
Description	Erythropoietin precursor.

PGCA_HUMAN
θ value	0.0563607 (rank : 5)	NC score	0.034975 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	821	Shared Neighborhood Hits	9
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

UBP2L_HUMAN
θ value	0.125558 (rank : 6)	NC score	0.121589 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

CEL_HUMAN
θ value	0.163984 (rank : 7)	NC score	0.032017 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	896	Shared Neighborhood Hits	10
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

NCOA5_HUMAN
θ value	0.21417 (rank : 8)	NC score	0.121299 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

UBP2L_MOUSE
θ value	0.279714 (rank : 9)	NC score	0.108174 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

NTKL_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.033163 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	326	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

UBQL3_HUMAN
θ value	1.06291 (rank : 11)	NC score	0.035493 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

K1543_HUMAN
θ value	1.38821 (rank : 12)	NC score	0.041553 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	435	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SYNJ1_MOUSE
θ value	1.38821 (rank : 13)	NC score	0.030649 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	516	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

EPO_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.096856 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	P01588, Q549U2, Q9UDZ0, Q9UEZ5, Q9UHA0	Gene names	EPO
Domain Architecture
Description	Erythropoietin precursor (Epoetin).

CAND2_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.026814 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

CIC_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.027735 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	992	Shared Neighborhood Hits	10
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

WASF4_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.047376 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	282	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

CIC_MOUSE
θ value	5.27518 (rank : 18)	NC score	0.029731 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	742	Shared Neighborhood Hits	9
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

GSHR_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.018430 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P00390, Q7Z5C9, Q9NP63	Gene names	GSR, GLUR, GRD1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

NRG2_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.021429 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

FAT2_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.006107 (rank : 35)
Query Neighborhood Hits	30	Target Neighborhood Hits	507	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

IF4G1_MOUSE
θ value	6.88961 (rank : 22)	NC score	0.017880 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	534	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

RERE_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.023733 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	779	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

WASF2_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.047223 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	280	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

DJBP_HUMAN
θ value	8.99809 (rank : 25)	NC score	0.015518 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

GP162_HUMAN
θ value	8.99809 (rank : 26)	NC score	0.011462 (rank : 33)
Query Neighborhood Hits	30	Target Neighborhood Hits	244	Shared Neighborhood Hits	2
SwissProt Accessions	Q16538, Q16664, Q59EH5, Q66K56	Gene names	GPR162, GRCA
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 162 (Gene-rich cluster gene A protein).

HLF_MOUSE
θ value	8.99809 (rank : 27)	NC score	0.013734 (rank : 32)
Query Neighborhood Hits	30	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

NAF1_HUMAN
θ value	8.99809 (rank : 28)	NC score	0.006235 (rank : 34)
Query Neighborhood Hits	30	Target Neighborhood Hits	937	Shared Neighborhood Hits	2
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NRG2_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.019767 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	392	Shared Neighborhood Hits	5
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

REXO1_MOUSE
θ value	8.99809 (rank : 30)	NC score	0.014088 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	166	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

CN032_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.075360 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	267	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

CN032_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.050967 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

RU1C_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.060392 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.059467 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

SF3A2_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.054470 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	263	Shared Neighborhood Hits	5
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

Hits sorted by NC score

TPO_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.76981e-150 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P40225, Q13020, Q15790, Q15791, Q15792	Gene names	THPO
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

TPO_MOUSE
NC score	0.818149 (rank : 2)	θ value	1.59483e-97 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	258	Shared Neighborhood Hits	8
SwissProt Accessions	P40226	Gene names	Thpo
Domain Architecture
Description	Thrombopoietin precursor (Megakaryocyte colony-stimulating factor) (Myeloproliferative leukemia virus oncogene ligand) (C-mpl ligand) (ML) (Megakaryocyte growth and development factor) (MGDF).

EPO_MOUSE
NC score	0.167642 (rank : 3)	θ value	0.0563607 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	P07321	Gene names	Epo
Domain Architecture
Description	Erythropoietin precursor.

NCOA5_MOUSE
NC score	0.135370 (rank : 4)	θ value	0.0330416 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W39	Gene names	Ncoa5
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

UBP2L_HUMAN
NC score	0.121589 (rank : 5)	θ value	0.125558 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

NCOA5_HUMAN
NC score	0.121299 (rank : 6)	θ value	0.21417 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCD5, Q6HA99, Q9H1F2, Q9H2T2, Q9H4Y9	Gene names	NCOA5, KIAA1637
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 5 (NCoA-5) (Coactivator independent of AF-2) (CIA).

UBP2L_MOUSE
NC score	0.108174 (rank : 7)	θ value	0.279714 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

EPO_HUMAN
NC score	0.096856 (rank : 8)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	P01588, Q549U2, Q9UDZ0, Q9UEZ5, Q9UHA0	Gene names	EPO
Domain Architecture
Description	Erythropoietin precursor (Epoetin).

CN032_HUMAN
NC score	0.075360 (rank : 9)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	267	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NDC0, Q96BG5	Gene names	C14orf32
Domain Architecture	No domain graphic available
Description	Protein C14orf32.

RU1C_HUMAN
NC score	0.060392 (rank : 10)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	30	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
NC score	0.059467 (rank : 11)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	30	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

SF3A2_HUMAN
NC score	0.054470 (rank : 12)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	30	Target Neighborhood Hits	263	Shared Neighborhood Hits	5
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

CN032_MOUSE
NC score	0.050967 (rank : 13)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	30	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BH93, Q3TF12, Q3TGL0, Q8CC90	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf32 homolog.

WASF4_HUMAN
NC score	0.047376 (rank : 14)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	282	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IV90	Gene names	WASF4, SCAR2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4).

WASF2_HUMAN
NC score	0.047223 (rank : 15)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	280	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

K1543_HUMAN
NC score	0.041553 (rank : 16)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	435	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

UBQL3_HUMAN
NC score	0.035493 (rank : 17)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

PGCA_HUMAN
NC score	0.034975 (rank : 18)	θ value	0.0563607 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	821	Shared Neighborhood Hits	9
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

NTKL_MOUSE
NC score	0.033163 (rank : 19)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	326	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

CEL_HUMAN
NC score	0.032017 (rank : 20)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	896	Shared Neighborhood Hits	10
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

SYNJ1_MOUSE
NC score	0.030649 (rank : 21)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	516	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

CIC_MOUSE
NC score	0.029731 (rank : 22)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	742	Shared Neighborhood Hits	9
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_HUMAN
NC score	0.027735 (rank : 23)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	992	Shared Neighborhood Hits	10
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CAND2_HUMAN
NC score	0.026814 (rank : 24)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

RERE_HUMAN
NC score	0.023733 (rank : 25)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	779	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

NRG2_HUMAN
NC score	0.021429 (rank : 26)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
NC score	0.019767 (rank : 27)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	392	Shared Neighborhood Hits	5
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

GSHR_HUMAN
NC score	0.018430 (rank : 28)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P00390, Q7Z5C9, Q9NP63	Gene names	GSR, GLUR, GRD1
Domain Architecture
Description	Glutathione reductase, mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).

IF4G1_MOUSE
NC score	0.017880 (rank : 29)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	534	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

DJBP_HUMAN
NC score	0.015518 (rank : 30)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

REXO1_MOUSE
NC score	0.014088 (rank : 31)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	166	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TT28, Q3UMP1, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29	Gene names	Rexo1, Kiaa1138, Tceb3bp1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Transcription elongation factor B polypeptide 3-binding protein 1).

HLF_MOUSE
NC score	0.013734 (rank : 32)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

GP162_HUMAN
NC score	0.011462 (rank : 33)	θ value	8.99809 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	244	Shared Neighborhood Hits	2
SwissProt Accessions	Q16538, Q16664, Q59EH5, Q66K56	Gene names	GPR162, GRCA
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 162 (Gene-rich cluster gene A protein).

NAF1_HUMAN
NC score	0.006235 (rank : 34)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	937	Shared Neighborhood Hits	2
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

FAT2_HUMAN
NC score	0.006107 (rank : 35)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	507	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).