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Network neighborhood for query Sequence : UTP20_HUMAN

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UTP20_HUMAN
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UTP20_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

UTP20_MOUSE
θ value	0 (rank : 2)	NC score	0.989022 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	Q5XG71, Q80V22, Q8BXH9, Q8CHL6, Q99K11	Gene names	Utp20, Drim
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein).

CI093_HUMAN
θ value	0.0148317 (rank : 3)	NC score	0.043231 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	1088	Shared Neighborhood Hits	21
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

RIMB1_HUMAN
θ value	0.0252991 (rank : 4)	NC score	0.054739 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	1479	Shared Neighborhood Hits	20
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

IF140_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.061623 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

FLIP1_HUMAN
θ value	0.47712 (rank : 6)	NC score	0.026316 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	1405	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

RIMB1_MOUSE
θ value	0.62314 (rank : 7)	NC score	0.038319 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	1376	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

TRI39_HUMAN
θ value	0.62314 (rank : 8)	NC score	0.018084 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	693	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

GOGA4_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.025426 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	2034	Shared Neighborhood Hits	26
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

THYG_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.018263 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

EVPL_MOUSE
θ value	1.38821 (rank : 11)	NC score	0.023083 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	952	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

WIPI1_MOUSE
θ value	1.38821 (rank : 12)	NC score	0.023983 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3E3, Q8BGE1, Q8R1A9, Q8R1C7	Gene names	Wipi1, D11Ertd498e
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa).

ABCAD_HUMAN
θ value	1.81305 (rank : 13)	NC score	0.011627 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

BCAS2_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.047795 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	O75934, Q6FGS0	Gene names	BCAS2, DAM1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 2 (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27).

BCAS2_MOUSE
θ value	1.81305 (rank : 15)	NC score	0.047795 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D287, Q3TKJ5, Q91YX8, Q9D2U4, Q9DAI0	Gene names	Bcas2, Dam1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 2 homolog (DNA amplified in mammary carcinoma 1 protein).

K0494_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.029259 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	230	Shared Neighborhood Hits	10
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

NEMO_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.031886 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	820	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

PTPRR_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.013015 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

CTGE2_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.021509 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	594	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

LRSM1_MOUSE
θ value	2.36792 (rank : 20)	NC score	0.019425 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	874	Shared Neighborhood Hits	18
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

STAT2_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.014066 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

AT8B4_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.008866 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TF62, Q9H727	Gene names	ATP8B4, KIAA1939
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IM (EC 3.6.3.1) (ATPase class I type 8B member 4).

CI065_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.029909 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUY3, Q5T304	Gene names	C9orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf65.

CNKR2_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.026255 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.026256 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

RBP17_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.028193 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2T7	Gene names	RANBP17
Domain Architecture
Description	Ran-binding protein 17.

CAND2_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.018792 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

GCC2_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.015408 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	1619	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

HELZ_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.016745 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

LRSM1_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.017744 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	1078	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

NF2L3_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.021063 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

NF2L3_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.021709 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

ZPBP1_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.020753 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BS86, Q15941, Q75KX9, Q75MI3	Gene names	ZPBP, ZPBP1
Domain Architecture	No domain graphic available
Description	Zona pellucida-binding protein 1 precursor (Sp38).

BRD1_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.009431 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BTAF1_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.013196 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

DHX9_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.010735 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

ETV4_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.008817 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

EXOC2_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.017562 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

MY18A_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.013314 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	1929	Shared Neighborhood Hits	26
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PRI1_HUMAN
θ value	5.27518 (rank : 40)	NC score	0.020078 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P49642	Gene names	PRIM1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

TCAL5_HUMAN
θ value	5.27518 (rank : 41)	NC score	0.008080 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	806	Shared Neighborhood Hits	7
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ANKR1_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.013227 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	316	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

MY18B_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.013631 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	1299	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

OS9_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.035550 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

PDE1C_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.006186 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).

POPD1_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.033456 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ES83, Q8C8L3	Gene names	Bves, Pop1, Popdc1
Domain Architecture
Description	Blood vessel epicardial substance (Popeye domain-containing protein 1) (Popeye protein 1).

SENP1_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.011706 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

ALG12_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.013404 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BV10, Q8NG10, Q96AA4	Gene names	ALG12
Domain Architecture
Description	Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6- mannosyltransferase (EC 2.4.1.-) (Mannosyltransferase ALG12 homolog) (hALG12) (Membrane protein SB87).

ANKR1_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.010760 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	308	Shared Neighborhood Hits	4
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ATR_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.019551 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

CAND2_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.015512 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

CLPP_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.021222 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q16740	Gene names	CLPP
Domain Architecture
Description	Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial precursor (EC 3.4.21.92) (Endopeptidase Clp).

CLPP_MOUSE
θ value	8.99809 (rank : 53)	NC score	0.020978 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	O88696, Q3TI13	Gene names	Clpp
Domain Architecture
Description	Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial precursor (EC 3.4.21.92) (Endopeptidase Clp).

CPSF3_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.011586 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKF6, O14769, Q96F36	Gene names	CPSF3, CPSF73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).

DESP_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.015179 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	1470	Shared Neighborhood Hits	21
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DHX9_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.009274 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

EEA1_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.014002 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	1796	Shared Neighborhood Hits	26
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

HEAT2_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.017319 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

ITSN1_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.010437 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	1757	Shared Neighborhood Hits	23
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

MBD4_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.012664 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2D7, Q792D2, Q8R3R3	Gene names	Mbd4
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase).

NEBU_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.009765 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	420	Shared Neighborhood Hits	8
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

NOC2L_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.014247 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WV70, Q8VE16	Gene names	Noc2l
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

PKN3_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.001488 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	1009	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PRKDC_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.010056 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

RBP17_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.026907 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q99NF8, Q9D4E3	Gene names	Ranbp17
Domain Architecture
Description	Ran-binding protein 17.

STMN2_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.013361 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	458	Shared Neighborhood Hits	12
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.013361 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	458	Shared Neighborhood Hits	12
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

TRAIP_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.017001 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	745	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TXND3_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.010372 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

Hits sorted by NC score

UTP20_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

UTP20_MOUSE
NC score	0.989022 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	Q5XG71, Q80V22, Q8BXH9, Q8CHL6, Q99K11	Gene names	Utp20, Drim
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein).

IF140_HUMAN
NC score	0.061623 (rank : 3)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	111	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

RIMB1_HUMAN
NC score	0.054739 (rank : 4)	θ value	0.0252991 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	1479	Shared Neighborhood Hits	20
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

BCAS2_HUMAN
NC score	0.047795 (rank : 5)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	O75934, Q6FGS0	Gene names	BCAS2, DAM1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 2 (DNA amplified in mammary carcinoma 1 protein) (Spliceosome-associated protein SPF 27).

BCAS2_MOUSE
NC score	0.047795 (rank : 6)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	80	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D287, Q3TKJ5, Q91YX8, Q9D2U4, Q9DAI0	Gene names	Bcas2, Dam1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 2 homolog (DNA amplified in mammary carcinoma 1 protein).

CI093_HUMAN
NC score	0.043231 (rank : 7)	θ value	0.0148317 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	1088	Shared Neighborhood Hits	21
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

RIMB1_MOUSE
NC score	0.038319 (rank : 8)	θ value	0.62314 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	1376	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

OS9_HUMAN
NC score	0.035550 (rank : 9)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	134	Shared Neighborhood Hits	8
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

POPD1_MOUSE
NC score	0.033456 (rank : 10)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ES83, Q8C8L3	Gene names	Bves, Pop1, Popdc1
Domain Architecture
Description	Blood vessel epicardial substance (Popeye domain-containing protein 1) (Popeye protein 1).

NEMO_HUMAN
NC score	0.031886 (rank : 11)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	820	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

CI065_HUMAN
NC score	0.029909 (rank : 12)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WUY3, Q5T304	Gene names	C9orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf65.

K0494_HUMAN
NC score	0.029259 (rank : 13)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	230	Shared Neighborhood Hits	10
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

RBP17_HUMAN
NC score	0.028193 (rank : 14)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2T7	Gene names	RANBP17
Domain Architecture
Description	Ran-binding protein 17.

RBP17_MOUSE
NC score	0.026907 (rank : 15)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q99NF8, Q9D4E3	Gene names	Ranbp17
Domain Architecture
Description	Ran-binding protein 17.

FLIP1_HUMAN
NC score	0.026316 (rank : 16)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	1405	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CNKR2_MOUSE
NC score	0.026256 (rank : 17)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.026255 (rank : 18)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

GOGA4_HUMAN
NC score	0.025426 (rank : 19)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	2034	Shared Neighborhood Hits	26
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

WIPI1_MOUSE
NC score	0.023983 (rank : 20)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3E3, Q8BGE1, Q8R1A9, Q8R1C7	Gene names	Wipi1, D11Ertd498e
Domain Architecture	No domain graphic available
Description	WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa).

EVPL_MOUSE
NC score	0.023083 (rank : 21)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	952	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

NF2L3_MOUSE
NC score	0.021709 (rank : 22)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTM4	Gene names	Nfe2l3, Nrf3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

CTGE2_HUMAN
NC score	0.021509 (rank : 23)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	594	Shared Neighborhood Hits	18
SwissProt Accessions	Q96RT6	Gene names	CTAGE1, CTAGE2
Domain Architecture	No domain graphic available
Description	Protein cTAGE-2.

CLPP_HUMAN
NC score	0.021222 (rank : 24)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	5	Shared Neighborhood Hits	4
SwissProt Accessions	Q16740	Gene names	CLPP
Domain Architecture
Description	Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial precursor (EC 3.4.21.92) (Endopeptidase Clp).

NF2L3_HUMAN
NC score	0.021063 (rank : 25)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4A8, Q6NUS0, Q7Z498, Q86UJ4, Q86VR5, Q9UQA4	Gene names	NFE2L3, NRF3
Domain Architecture	No domain graphic available
Description	Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3).

CLPP_MOUSE
NC score	0.020978 (rank : 26)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	O88696, Q3TI13	Gene names	Clpp
Domain Architecture
Description	Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial precursor (EC 3.4.21.92) (Endopeptidase Clp).

ZPBP1_HUMAN
NC score	0.020753 (rank : 27)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BS86, Q15941, Q75KX9, Q75MI3	Gene names	ZPBP, ZPBP1
Domain Architecture	No domain graphic available
Description	Zona pellucida-binding protein 1 precursor (Sp38).

PRI1_HUMAN
NC score	0.020078 (rank : 28)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P49642	Gene names	PRIM1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

ATR_MOUSE
NC score	0.019551 (rank : 29)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

LRSM1_MOUSE
NC score	0.019425 (rank : 30)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	874	Shared Neighborhood Hits	18
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

CAND2_MOUSE
NC score	0.018792 (rank : 31)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

THYG_HUMAN
NC score	0.018263 (rank : 32)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	154	Shared Neighborhood Hits	2
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TRI39_HUMAN
NC score	0.018084 (rank : 33)	θ value	0.62314 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	693	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

LRSM1_HUMAN
NC score	0.017744 (rank : 34)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	1078	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

EXOC2_HUMAN
NC score	0.017562 (rank : 35)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

HEAT2_HUMAN
NC score	0.017319 (rank : 36)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

TRAIP_MOUSE
NC score	0.017001 (rank : 37)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	745	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

HELZ_HUMAN
NC score	0.016745 (rank : 38)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	198	Shared Neighborhood Hits	3
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

CAND2_HUMAN
NC score	0.015512 (rank : 39)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

GCC2_MOUSE
NC score	0.015408 (rank : 40)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	1619	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

DESP_HUMAN
NC score	0.015179 (rank : 41)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	1470	Shared Neighborhood Hits	21
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

NOC2L_MOUSE
NC score	0.014247 (rank : 42)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WV70, Q8VE16	Gene names	Noc2l
Domain Architecture
Description	Nucleolar complex protein 2 homolog (Protein NOC2 homolog) (NOC2- like).

STAT2_MOUSE
NC score	0.014066 (rank : 43)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

EEA1_HUMAN
NC score	0.014002 (rank : 44)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	1796	Shared Neighborhood Hits	26
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

MY18B_HUMAN
NC score	0.013631 (rank : 45)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	1299	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

ALG12_HUMAN
NC score	0.013404 (rank : 46)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BV10, Q8NG10, Q96AA4	Gene names	ALG12
Domain Architecture
Description	Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6- mannosyltransferase (EC 2.4.1.-) (Mannosyltransferase ALG12 homolog) (hALG12) (Membrane protein SB87).

STMN2_HUMAN
NC score	0.013361 (rank : 47)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	458	Shared Neighborhood Hits	12
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
NC score	0.013361 (rank : 48)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	458	Shared Neighborhood Hits	12
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

MY18A_HUMAN
NC score	0.013314 (rank : 49)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	1929	Shared Neighborhood Hits	26
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ANKR1_MOUSE
NC score	0.013227 (rank : 50)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	316	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

BTAF1_HUMAN
NC score	0.013196 (rank : 51)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

PTPRR_MOUSE
NC score	0.013015 (rank : 52)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

MBD4_MOUSE
NC score	0.012664 (rank : 53)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2D7, Q792D2, Q8R3R3	Gene names	Mbd4
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase).

SENP1_MOUSE
NC score	0.011706 (rank : 54)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

ABCAD_HUMAN
NC score	0.011627 (rank : 55)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

CPSF3_HUMAN
NC score	0.011586 (rank : 56)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKF6, O14769, Q96F36	Gene names	CPSF3, CPSF73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).

ANKR1_HUMAN
NC score	0.010760 (rank : 57)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	308	Shared Neighborhood Hits	4
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

DHX9_HUMAN
NC score	0.010735 (rank : 58)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q08211, Q5VY62, Q6PD69, Q99556	Gene names	DHX9, DDX9, NDH2
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9).

ITSN1_HUMAN
NC score	0.010437 (rank : 59)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	1757	Shared Neighborhood Hits	23
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

TXND3_HUMAN
NC score	0.010372 (rank : 60)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

PRKDC_HUMAN
NC score	0.010056 (rank : 61)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

NEBU_HUMAN
NC score	0.009765 (rank : 62)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	420	Shared Neighborhood Hits	8
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

BRD1_HUMAN
NC score	0.009431 (rank : 63)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

DHX9_MOUSE
NC score	0.009274 (rank : 64)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	O70133, O35931, O54703, Q5FWY1, Q6R5F7, Q9CSA2	Gene names	Dhx9, Ddx9
Domain Architecture
Description	ATP-dependent RNA helicase A (EC 3.6.1.-) (Nuclear DNA helicase II) (NDH II) (DEAH box protein 9) (mHEL-5).

AT8B4_HUMAN
NC score	0.008866 (rank : 65)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TF62, Q9H727	Gene names	ATP8B4, KIAA1939
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IM (EC 3.6.3.1) (ATPase class I type 8B member 4).

ETV4_MOUSE
NC score	0.008817 (rank : 66)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

TCAL5_HUMAN
NC score	0.008080 (rank : 67)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	806	Shared Neighborhood Hits	7
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

PDE1C_HUMAN
NC score	0.006186 (rank : 68)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).

PKN3_MOUSE
NC score	0.001488 (rank : 69)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	1009	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).