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Network neighborhood for query Sequence : ETV4_MOUSE

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ETV4_MOUSE
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ETV4_HUMAN
θ value	0 (rank : 1)	NC score	0.993690 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	P43268, Q96AW9	Gene names	ETV4, E1AF
Domain Architecture	No domain graphic available
Description	ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F).

ETV4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

ETV1_MOUSE
θ value	1.4755e-135 (rank : 3)	NC score	0.976842 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	92	Shared Neighborhood Hits	44
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

ETV1_HUMAN
θ value	4.29305e-135 (rank : 4)	NC score	0.976116 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	107	Shared Neighborhood Hits	45
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

ETV5_HUMAN
θ value	4.03687e-117 (rank : 5)	NC score	0.966686 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	181	Shared Neighborhood Hits	49
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

ETV5_MOUSE
θ value	4.03687e-117 (rank : 6)	NC score	0.945361 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	328	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

ETS1_HUMAN
θ value	1.2049e-28 (rank : 7)	NC score	0.869952 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	49	Shared Neighborhood Hits	41
SwissProt Accessions	P14921, Q14278, Q16080	Gene names	ETS1
Domain Architecture
Description	C-ets-1 protein (p54).

ETS1_MOUSE
θ value	1.2049e-28 (rank : 8)	NC score	0.869669 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	P27577, Q61403	Gene names	Ets1, Ets-1
Domain Architecture
Description	C-ets-1 protein (p54).

ELK4_MOUSE
θ value	2.68423e-28 (rank : 9)	NC score	0.875934 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	P41158	Gene names	Elk4, Sap1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

ETS2_HUMAN
θ value	7.80994e-28 (rank : 10)	NC score	0.867318 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	P15036	Gene names	ETS2
Domain Architecture
Description	C-ets-2 protein.

ETS2_MOUSE
θ value	7.80994e-28 (rank : 11)	NC score	0.866986 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	52	Shared Neighborhood Hits	41
SwissProt Accessions	P15037	Gene names	Ets2
Domain Architecture
Description	C-ets-2 protein.

ELK4_HUMAN
θ value	1.73987e-27 (rank : 12)	NC score	0.860734 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	184	Shared Neighborhood Hits	48
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

ELK1_HUMAN
θ value	4.28545e-26 (rank : 13)	NC score	0.875152 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	112	Shared Neighborhood Hits	42
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

ELK1_MOUSE
θ value	4.28545e-26 (rank : 14)	NC score	0.873109 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

ELK3_HUMAN
θ value	1.62847e-25 (rank : 15)	NC score	0.880055 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	64	Shared Neighborhood Hits	42
SwissProt Accessions	P41970, Q6FG57, Q6GU29, Q9UD17	Gene names	ELK3, NET, SAP2
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP) (SRF accessory protein 2) (SAP-2).

ELK3_MOUSE
θ value	4.73814e-25 (rank : 16)	NC score	0.877248 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	72	Shared Neighborhood Hits	42
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

ERG_MOUSE
θ value	6.18819e-25 (rank : 17)	NC score	0.843397 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	P81270, Q8C5L4, Q920K7, Q920K8, Q920K9	Gene names	Erg, Erg-3
Domain Architecture
Description	Transcriptional regulator ERG.

FLI1_HUMAN
θ value	6.18819e-25 (rank : 18)	NC score	0.843577 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q01543, Q14319, Q92480, Q9UE07	Gene names	FLI1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Fli-1 proto- oncogene) (ERGB transcription factor).

FLI1_MOUSE
θ value	6.18819e-25 (rank : 19)	NC score	0.845794 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	56	Shared Neighborhood Hits	41
SwissProt Accessions	P26323	Gene names	Fli1, Fli-1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Retroviral integration site protein Fli-1).

ERG_HUMAN
θ value	1.05554e-24 (rank : 20)	NC score	0.843414 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	P11308, Q16113	Gene names	ERG
Domain Architecture
Description	Transcriptional regulator ERG (Transforming protein ERG).

ETV2_HUMAN
θ value	5.23862e-24 (rank : 21)	NC score	0.875840 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	O00321, Q9UEA0	Gene names	ETV2, ER71, ETSRP71
Domain Architecture
Description	ETS translocation variant 2 (Ets-related protein 71).

ETV2_MOUSE
θ value	3.39556e-23 (rank : 22)	NC score	0.870772 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	58	Shared Neighborhood Hits	41
SwissProt Accessions	P41163	Gene names	Etv2, Er71, Etsrp71
Domain Architecture
Description	ETS translocation variant 2 (Ets-related protein 71).

GABPA_MOUSE
θ value	3.39556e-23 (rank : 23)	NC score	0.850003 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	50	Shared Neighborhood Hits	41
SwissProt Accessions	Q00422	Gene names	Gabpa, E4tf1a
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha).

GABPA_HUMAN
θ value	7.56453e-23 (rank : 24)	NC score	0.849000 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	55	Shared Neighborhood Hits	41
SwissProt Accessions	Q06546, Q12939	Gene names	GABPA, E4TF1A
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha) (Transcription factor E4TF1-60) (Nuclear respiratory factor 2 subunit alpha).

ERF_HUMAN
θ value	1.02238e-19 (rank : 25)	NC score	0.818438 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	162	Shared Neighborhood Hits	42
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ERF_MOUSE
θ value	1.02238e-19 (rank : 26)	NC score	0.818106 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	160	Shared Neighborhood Hits	43
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

ETV3_HUMAN
θ value	3.88503e-19 (rank : 27)	NC score	0.785141 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	312	Shared Neighborhood Hits	46
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ETV3_MOUSE
θ value	3.88503e-19 (rank : 28)	NC score	0.808954 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ELF4_HUMAN
θ value	3.28887e-18 (rank : 29)	NC score	0.787713 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	87	Shared Neighborhood Hits	42
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

ELF1_MOUSE
θ value	4.29542e-18 (rank : 30)	NC score	0.781826 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	139	Shared Neighborhood Hits	45
SwissProt Accessions	Q60775	Gene names	Elf1
Domain Architecture
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

ELF1_HUMAN
θ value	5.60996e-18 (rank : 31)	NC score	0.787370 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	P32519, Q9UDE1	Gene names	ELF1
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

ELF4_MOUSE
θ value	9.56915e-18 (rank : 32)	NC score	0.768211 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	191	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

SPDEF_HUMAN
θ value	1.38178e-16 (rank : 33)	NC score	0.817739 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	56	Shared Neighborhood Hits	41
SwissProt Accessions	O95238	Gene names	SPDEF, PDEF, PSE
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).

ELF2_HUMAN
θ value	1.80466e-16 (rank : 34)	NC score	0.787685 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	78	Shared Neighborhood Hits	42
SwissProt Accessions	Q15723, Q15724, Q15725, Q6P1K5	Gene names	ELF2, NERF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

ELF2_MOUSE
θ value	1.80466e-16 (rank : 35)	NC score	0.787128 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JHC9, Q6NST2, Q8BTX8, Q9JHC7, Q9JHC8, Q9JHD0	Gene names	Elf2, Nerf
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

SPDEF_MOUSE
θ value	1.80466e-16 (rank : 36)	NC score	0.815582 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	56	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTP3	Gene names	Spdef, Pdef, Pse
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).

ETV6_HUMAN
θ value	4.44505e-15 (rank : 37)	NC score	0.780334 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ETV6_MOUSE
θ value	1.68911e-14 (rank : 38)	NC score	0.781024 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	P97360	Gene names	Etv6, Tel, Tel1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ETV7_HUMAN
θ value	4.59992e-12 (rank : 39)	NC score	0.802621 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	61	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y603, Q9NZ65, Q9NZ66, Q9NZ68, Q9NZR8, Q9UNJ7, Q9Y5K4, Q9Y604	Gene names	ETV7, TEL2, TELB, TREF
Domain Architecture
Description	Transcription factor ETV7 (Transcription factor Tel-2) (ETS-related protein Tel2) (Tel-related Ets factor).

ELF5_HUMAN
θ value	1.133e-10 (rank : 40)	NC score	0.754488 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UKW6, O95175, Q8N2K9, Q96QY3, Q9UKW5	Gene names	ELF5
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-specific Ets transcription factor 2) (ESE-2) (Epithelium- restricted ESE-1-related Ets factor).

ELF5_MOUSE
θ value	1.133e-10 (rank : 41)	NC score	0.754237 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	50	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VDK3, Q921H5, Q9Z2K6	Gene names	Elf5
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-5 (E74-like factor 5).

GSCR1_HUMAN
θ value	0.0193708 (rank : 42)	NC score	0.062896 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	674	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

GA2L2_MOUSE
θ value	0.0563607 (rank : 43)	NC score	0.026472 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

DPOLM_MOUSE
θ value	0.0736092 (rank : 44)	NC score	0.034852 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JIW4, Q9JJW9	Gene names	Polm
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

MYST3_MOUSE
θ value	0.163984 (rank : 45)	NC score	0.024870 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	688	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PDC6I_HUMAN
θ value	0.21417 (rank : 46)	NC score	0.033900 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

SPRR3_MOUSE
θ value	0.47712 (rank : 47)	NC score	0.044114 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

THSD1_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.023389 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

PROX1_MOUSE
θ value	0.62314 (rank : 49)	NC score	0.026163 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

ZHX3_MOUSE
θ value	0.813845 (rank : 50)	NC score	0.012020 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	321	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

IP3KB_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.015807 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

VAX2_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.008969 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	338	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTP9	Gene names	Vax2, Vex
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 2 (Ventral retina homeodomain protein).

PCLO_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.017582 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	2275	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PTPRN_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.006763 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

LNK_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.009521 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	151	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

MBD2_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.010541 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

RIN3_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.015978 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SOX9_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.007456 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

DGKK_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.015335 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	378	Shared Neighborhood Hits	14
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

IWS1_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.008185 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	1241	Shared Neighborhood Hits	17
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NCOA6_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.031933 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	1202	Shared Neighborhood Hits	37
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.033081 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	1076	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PML_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.010132 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	248	Shared Neighborhood Hits	4
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

T22D4_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.014368 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

THSD1_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.018603 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TSH2_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.005849 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	467	Shared Neighborhood Hits	3
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

BSN_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.019644 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	2057	Shared Neighborhood Hits	38
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CSKI2_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.003707 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	812	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

FOXJ3_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.011577 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	177	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

KCNC3_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.003125 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	256	Shared Neighborhood Hits	8
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

NRG2_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.004582 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

PROX1_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.021394 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	Q92786, Q5SW76, Q8TB91	Gene names	PROX1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

SNTB2_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.007709 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

VAX2_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.004796 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	337	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIW0	Gene names	VAX2
Domain Architecture
Description	Ventral anterior homeobox 2.

AATK_MOUSE
θ value	5.27518 (rank : 75)	NC score	-0.002794 (rank : 104)
Query Neighborhood Hits	100	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ACD_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.020546 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

BAT2_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.020968 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	931	Shared Neighborhood Hits	25
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BRD4_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.025838 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	851	Shared Neighborhood Hits	23
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

OS9_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.011875 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

TCF7_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.007530 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	186	Shared Neighborhood Hits	11
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

UTP20_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.008817 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

AMHR2_HUMAN
θ value	6.88961 (rank : 82)	NC score	-0.001423 (rank : 103)
Query Neighborhood Hits	100	Target Neighborhood Hits	715	Shared Neighborhood Hits	5
SwissProt Accessions	Q16671, Q13762	Gene names	AMHR2, AMHR
Domain Architecture
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII).

CNOT4_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.012576 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

PGBM_MOUSE
θ value	6.88961 (rank : 84)	NC score	-0.003270 (rank : 105)
Query Neighborhood Hits	100	Target Neighborhood Hits	1073	Shared Neighborhood Hits	4
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SIM2_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.003184 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SPR1A_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.027185 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	136	Shared Neighborhood Hits	13
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

TCGAP_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.009707 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	872	Shared Neighborhood Hits	23
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TJAP1_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.006032 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

CEBPA_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.005356 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	P53566, Q91XB6	Gene names	Cebpa
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

CNOT4_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.013444 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	277	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CSKI2_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.001178 (rank : 102)
Query Neighborhood Hits	100	Target Neighborhood Hits	747	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

GSLG1_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.011909 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q61543, Q9QZ40	Gene names	Glg1, Esl1, Mg160, Selel
Domain Architecture
Description	Golgi apparatus protein 1 precursor (Golgi sialoglycoprotein MG-160) (E-selectin ligand 1) (ESL-1) (Selel).

MILK1_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.005464 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	427	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

REST_MOUSE
θ value	8.99809 (rank : 94)	NC score	-0.004378 (rank : 106)
Query Neighborhood Hits	100	Target Neighborhood Hits	1506	Shared Neighborhood Hits	8
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SOX9_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.006783 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SYN1_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.009727 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TAB3_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.012119 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TAB3_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.010767 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	273	Shared Neighborhood Hits	13
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

VTNC_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.003662 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

WNK2_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.001563 (rank : 101)
Query Neighborhood Hits	100	Target Neighborhood Hits	1407	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

SPI1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.492720 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	50	Shared Neighborhood Hits	40
SwissProt Accessions	P17947	Gene names	SPI1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein).

SPI1_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.493602 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	47	Shared Neighborhood Hits	39
SwissProt Accessions	P17433, Q99L57	Gene names	Spi1, Sfpi-1, Sfpi1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein) (SFFV proviral integration 1 protein).

SPIB_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.495908 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q01892, Q15359	Gene names	SPIB
Domain Architecture
Description	Transcription factor Spi-B.

SPIB_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.480797 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	65	Shared Neighborhood Hits	39
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

SPIC_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.413512 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N5J4	Gene names	SPIC
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-C.

SPIC_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.387943 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P3D7, Q9Z0Y0	Gene names	Spic
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-C (Pu.1-related factor) (Prf).

Hits sorted by NC score

ETV4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	100
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

ETV4_HUMAN
NC score	0.993690 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	100	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	P43268, Q96AW9	Gene names	ETV4, E1AF
Domain Architecture	No domain graphic available
Description	ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F).

ETV1_MOUSE
NC score	0.976842 (rank : 3)	θ value	1.4755e-135 (rank : 3)
Query Neighborhood Hits	100	Target Neighborhood Hits	92	Shared Neighborhood Hits	44
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

ETV1_HUMAN
NC score	0.976116 (rank : 4)	θ value	4.29305e-135 (rank : 4)
Query Neighborhood Hits	100	Target Neighborhood Hits	107	Shared Neighborhood Hits	45
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

ETV5_HUMAN
NC score	0.966686 (rank : 5)	θ value	4.03687e-117 (rank : 5)
Query Neighborhood Hits	100	Target Neighborhood Hits	181	Shared Neighborhood Hits	49
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

ETV5_MOUSE
NC score	0.945361 (rank : 6)	θ value	4.03687e-117 (rank : 6)
Query Neighborhood Hits	100	Target Neighborhood Hits	328	Shared Neighborhood Hits	52
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

ELK3_HUMAN
NC score	0.880055 (rank : 7)	θ value	1.62847e-25 (rank : 15)
Query Neighborhood Hits	100	Target Neighborhood Hits	64	Shared Neighborhood Hits	42
SwissProt Accessions	P41970, Q6FG57, Q6GU29, Q9UD17	Gene names	ELK3, NET, SAP2
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP) (SRF accessory protein 2) (SAP-2).

ELK3_MOUSE
NC score	0.877248 (rank : 8)	θ value	4.73814e-25 (rank : 16)
Query Neighborhood Hits	100	Target Neighborhood Hits	72	Shared Neighborhood Hits	42
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

ELK4_MOUSE
NC score	0.875934 (rank : 9)	θ value	2.68423e-28 (rank : 9)
Query Neighborhood Hits	100	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	P41158	Gene names	Elk4, Sap1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

ETV2_HUMAN
NC score	0.875840 (rank : 10)	θ value	5.23862e-24 (rank : 21)
Query Neighborhood Hits	100	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	O00321, Q9UEA0	Gene names	ETV2, ER71, ETSRP71
Domain Architecture
Description	ETS translocation variant 2 (Ets-related protein 71).

ELK1_HUMAN
NC score	0.875152 (rank : 11)	θ value	4.28545e-26 (rank : 13)
Query Neighborhood Hits	100	Target Neighborhood Hits	112	Shared Neighborhood Hits	42
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

ELK1_MOUSE
NC score	0.873109 (rank : 12)	θ value	4.28545e-26 (rank : 14)
Query Neighborhood Hits	100	Target Neighborhood Hits	110	Shared Neighborhood Hits	42
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

ETV2_MOUSE
NC score	0.870772 (rank : 13)	θ value	3.39556e-23 (rank : 22)
Query Neighborhood Hits	100	Target Neighborhood Hits	58	Shared Neighborhood Hits	41
SwissProt Accessions	P41163	Gene names	Etv2, Er71, Etsrp71
Domain Architecture
Description	ETS translocation variant 2 (Ets-related protein 71).

ETS1_HUMAN
NC score	0.869952 (rank : 14)	θ value	1.2049e-28 (rank : 7)
Query Neighborhood Hits	100	Target Neighborhood Hits	49	Shared Neighborhood Hits	41
SwissProt Accessions	P14921, Q14278, Q16080	Gene names	ETS1
Domain Architecture
Description	C-ets-1 protein (p54).

ETS1_MOUSE
NC score	0.869669 (rank : 15)	θ value	1.2049e-28 (rank : 8)
Query Neighborhood Hits	100	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	P27577, Q61403	Gene names	Ets1, Ets-1
Domain Architecture
Description	C-ets-1 protein (p54).

ETS2_HUMAN
NC score	0.867318 (rank : 16)	θ value	7.80994e-28 (rank : 10)
Query Neighborhood Hits	100	Target Neighborhood Hits	53	Shared Neighborhood Hits	41
SwissProt Accessions	P15036	Gene names	ETS2
Domain Architecture
Description	C-ets-2 protein.

ETS2_MOUSE
NC score	0.866986 (rank : 17)	θ value	7.80994e-28 (rank : 11)
Query Neighborhood Hits	100	Target Neighborhood Hits	52	Shared Neighborhood Hits	41
SwissProt Accessions	P15037	Gene names	Ets2
Domain Architecture
Description	C-ets-2 protein.

ELK4_HUMAN
NC score	0.860734 (rank : 18)	θ value	1.73987e-27 (rank : 12)
Query Neighborhood Hits	100	Target Neighborhood Hits	184	Shared Neighborhood Hits	48
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

GABPA_MOUSE
NC score	0.850003 (rank : 19)	θ value	3.39556e-23 (rank : 23)
Query Neighborhood Hits	100	Target Neighborhood Hits	50	Shared Neighborhood Hits	41
SwissProt Accessions	Q00422	Gene names	Gabpa, E4tf1a
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha).

GABPA_HUMAN
NC score	0.849000 (rank : 20)	θ value	7.56453e-23 (rank : 24)
Query Neighborhood Hits	100	Target Neighborhood Hits	55	Shared Neighborhood Hits	41
SwissProt Accessions	Q06546, Q12939	Gene names	GABPA, E4TF1A
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha) (Transcription factor E4TF1-60) (Nuclear respiratory factor 2 subunit alpha).

FLI1_MOUSE
NC score	0.845794 (rank : 21)	θ value	6.18819e-25 (rank : 19)
Query Neighborhood Hits	100	Target Neighborhood Hits	56	Shared Neighborhood Hits	41
SwissProt Accessions	P26323	Gene names	Fli1, Fli-1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Retroviral integration site protein Fli-1).

FLI1_HUMAN
NC score	0.843577 (rank : 22)	θ value	6.18819e-25 (rank : 18)
Query Neighborhood Hits	100	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q01543, Q14319, Q92480, Q9UE07	Gene names	FLI1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Fli-1 proto- oncogene) (ERGB transcription factor).

ERG_HUMAN
NC score	0.843414 (rank : 23)	θ value	1.05554e-24 (rank : 20)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	41
SwissProt Accessions	P11308, Q16113	Gene names	ERG
Domain Architecture
Description	Transcriptional regulator ERG (Transforming protein ERG).

ERG_MOUSE
NC score	0.843397 (rank : 24)	θ value	6.18819e-25 (rank : 17)
Query Neighborhood Hits	100	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	P81270, Q8C5L4, Q920K7, Q920K8, Q920K9	Gene names	Erg, Erg-3
Domain Architecture
Description	Transcriptional regulator ERG.

ERF_HUMAN
NC score	0.818438 (rank : 25)	θ value	1.02238e-19 (rank : 25)
Query Neighborhood Hits	100	Target Neighborhood Hits	162	Shared Neighborhood Hits	42
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ERF_MOUSE
NC score	0.818106 (rank : 26)	θ value	1.02238e-19 (rank : 26)
Query Neighborhood Hits	100	Target Neighborhood Hits	160	Shared Neighborhood Hits	43
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

SPDEF_HUMAN
NC score	0.817739 (rank : 27)	θ value	1.38178e-16 (rank : 33)
Query Neighborhood Hits	100	Target Neighborhood Hits	56	Shared Neighborhood Hits	41
SwissProt Accessions	O95238	Gene names	SPDEF, PDEF, PSE
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).

SPDEF_MOUSE
NC score	0.815582 (rank : 28)	θ value	1.80466e-16 (rank : 36)
Query Neighborhood Hits	100	Target Neighborhood Hits	56	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTP3	Gene names	Spdef, Pdef, Pse
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).

ETV3_MOUSE
NC score	0.808954 (rank : 29)	θ value	3.88503e-19 (rank : 28)
Query Neighborhood Hits	100	Target Neighborhood Hits	128	Shared Neighborhood Hits	44
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ETV7_HUMAN
NC score	0.802621 (rank : 30)	θ value	4.59992e-12 (rank : 39)
Query Neighborhood Hits	100	Target Neighborhood Hits	61	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y603, Q9NZ65, Q9NZ66, Q9NZ68, Q9NZR8, Q9UNJ7, Q9Y5K4, Q9Y604	Gene names	ETV7, TEL2, TELB, TREF
Domain Architecture
Description	Transcription factor ETV7 (Transcription factor Tel-2) (ETS-related protein Tel2) (Tel-related Ets factor).

ELF4_HUMAN
NC score	0.787713 (rank : 31)	θ value	3.28887e-18 (rank : 29)
Query Neighborhood Hits	100	Target Neighborhood Hits	87	Shared Neighborhood Hits	42
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

ELF2_HUMAN
NC score	0.787685 (rank : 32)	θ value	1.80466e-16 (rank : 34)
Query Neighborhood Hits	100	Target Neighborhood Hits	78	Shared Neighborhood Hits	42
SwissProt Accessions	Q15723, Q15724, Q15725, Q6P1K5	Gene names	ELF2, NERF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

ELF1_HUMAN
NC score	0.787370 (rank : 33)	θ value	5.60996e-18 (rank : 31)
Query Neighborhood Hits	100	Target Neighborhood Hits	104	Shared Neighborhood Hits	41
SwissProt Accessions	P32519, Q9UDE1	Gene names	ELF1
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

ELF2_MOUSE
NC score	0.787128 (rank : 34)	θ value	1.80466e-16 (rank : 35)
Query Neighborhood Hits	100	Target Neighborhood Hits	81	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JHC9, Q6NST2, Q8BTX8, Q9JHC7, Q9JHC8, Q9JHD0	Gene names	Elf2, Nerf
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

ETV3_HUMAN
NC score	0.785141 (rank : 35)	θ value	3.88503e-19 (rank : 27)
Query Neighborhood Hits	100	Target Neighborhood Hits	312	Shared Neighborhood Hits	46
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ELF1_MOUSE
NC score	0.781826 (rank : 36)	θ value	4.29542e-18 (rank : 30)
Query Neighborhood Hits	100	Target Neighborhood Hits	139	Shared Neighborhood Hits	45
SwissProt Accessions	Q60775	Gene names	Elf1
Domain Architecture
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

ETV6_MOUSE
NC score	0.781024 (rank : 37)	θ value	1.68911e-14 (rank : 38)
Query Neighborhood Hits	100	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	P97360	Gene names	Etv6, Tel, Tel1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ETV6_HUMAN
NC score	0.780334 (rank : 38)	θ value	4.44505e-15 (rank : 37)
Query Neighborhood Hits	100	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ELF4_MOUSE
NC score	0.768211 (rank : 39)	θ value	9.56915e-18 (rank : 32)
Query Neighborhood Hits	100	Target Neighborhood Hits	191	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

ELF5_HUMAN
NC score	0.754488 (rank : 40)	θ value	1.133e-10 (rank : 40)
Query Neighborhood Hits	100	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UKW6, O95175, Q8N2K9, Q96QY3, Q9UKW5	Gene names	ELF5
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-specific Ets transcription factor 2) (ESE-2) (Epithelium- restricted ESE-1-related Ets factor).

ELF5_MOUSE
NC score	0.754237 (rank : 41)	θ value	1.133e-10 (rank : 41)
Query Neighborhood Hits	100	Target Neighborhood Hits	50	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VDK3, Q921H5, Q9Z2K6	Gene names	Elf5
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-5 (E74-like factor 5).

SPIB_HUMAN
NC score	0.495908 (rank : 42)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	100	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q01892, Q15359	Gene names	SPIB
Domain Architecture
Description	Transcription factor Spi-B.

SPI1_MOUSE
NC score	0.493602 (rank : 43)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	100	Target Neighborhood Hits	47	Shared Neighborhood Hits	39
SwissProt Accessions	P17433, Q99L57	Gene names	Spi1, Sfpi-1, Sfpi1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein) (SFFV proviral integration 1 protein).

SPI1_HUMAN
NC score	0.492720 (rank : 44)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	100	Target Neighborhood Hits	50	Shared Neighborhood Hits	40
SwissProt Accessions	P17947	Gene names	SPI1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein).

SPIB_MOUSE
NC score	0.480797 (rank : 45)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	100	Target Neighborhood Hits	65	Shared Neighborhood Hits	39
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

SPIC_HUMAN
NC score	0.413512 (rank : 46)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	100	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N5J4	Gene names	SPIC
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-C.

SPIC_MOUSE
NC score	0.387943 (rank : 47)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	100	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P3D7, Q9Z0Y0	Gene names	Spic
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-C (Pu.1-related factor) (Prf).

GSCR1_HUMAN
NC score	0.062896 (rank : 48)	θ value	0.0193708 (rank : 42)
Query Neighborhood Hits	100	Target Neighborhood Hits	674	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SPRR3_MOUSE
NC score	0.044114 (rank : 49)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	100	Target Neighborhood Hits	106	Shared Neighborhood Hits	9
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

DPOLM_MOUSE
NC score	0.034852 (rank : 50)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	100	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JIW4, Q9JJW9	Gene names	Polm
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

PDC6I_HUMAN
NC score	0.033900 (rank : 51)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	100	Target Neighborhood Hits	278	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WUM4, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5	Gene names	PDCD6IP, AIP1, ALIX, KIAA1375
Domain Architecture
Description	Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95).

NCOA6_MOUSE
NC score	0.033081 (rank : 52)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	100	Target Neighborhood Hits	1076	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOA6_HUMAN
NC score	0.031933 (rank : 53)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	100	Target Neighborhood Hits	1202	Shared Neighborhood Hits	37
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SPR1A_HUMAN
NC score	0.027185 (rank : 54)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	100	Target Neighborhood Hits	136	Shared Neighborhood Hits	13
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

GA2L2_MOUSE
NC score	0.026472 (rank : 55)	θ value	0.0563607 (rank : 43)
Query Neighborhood Hits	100	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

PROX1_MOUSE
NC score	0.026163 (rank : 56)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	100	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	P48437, O88478, Q3UPV1, Q543D8	Gene names	Prox1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

BRD4_HUMAN
NC score	0.025838 (rank : 57)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	100	Target Neighborhood Hits	851	Shared Neighborhood Hits	23
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

MYST3_MOUSE
NC score	0.024870 (rank : 58)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	100	Target Neighborhood Hits	688	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

THSD1_MOUSE
NC score	0.023389 (rank : 59)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	100	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

PROX1_HUMAN
NC score	0.021394 (rank : 60)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	100	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	Q92786, Q5SW76, Q8TB91	Gene names	PROX1
Domain Architecture
Description	Homeobox prospero-like protein PROX1 (PROX 1).

BAT2_HUMAN
NC score	0.020968 (rank : 61)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	100	Target Neighborhood Hits	931	Shared Neighborhood Hits	25
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ACD_HUMAN
NC score	0.020546 (rank : 62)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	100	Target Neighborhood Hits	143	Shared Neighborhood Hits	8
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

BSN_MOUSE
NC score	0.019644 (rank : 63)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	100	Target Neighborhood Hits	2057	Shared Neighborhood Hits	38
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

THSD1_HUMAN
NC score	0.018603 (rank : 64)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	100	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

PCLO_MOUSE
NC score	0.017582 (rank : 65)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	100	Target Neighborhood Hits	2275	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RIN3_HUMAN
NC score	0.015978 (rank : 66)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	100	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

IP3KB_HUMAN
NC score	0.015807 (rank : 67)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	100	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

DGKK_HUMAN
NC score	0.015335 (rank : 68)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	100	Target Neighborhood Hits	378	Shared Neighborhood Hits	14
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

T22D4_HUMAN
NC score	0.014368 (rank : 69)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	100	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

CNOT4_MOUSE
NC score	0.013444 (rank : 70)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	100	Target Neighborhood Hits	277	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_HUMAN
NC score	0.012576 (rank : 71)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	100	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

TAB3_HUMAN
NC score	0.012119 (rank : 72)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	100	Target Neighborhood Hits	168	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

ZHX3_MOUSE
NC score	0.012020 (rank : 73)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	100	Target Neighborhood Hits	321	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

GSLG1_MOUSE
NC score	0.011909 (rank : 74)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	100	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q61543, Q9QZ40	Gene names	Glg1, Esl1, Mg160, Selel
Domain Architecture
Description	Golgi apparatus protein 1 precursor (Golgi sialoglycoprotein MG-160) (E-selectin ligand 1) (ESL-1) (Selel).

OS9_HUMAN
NC score	0.011875 (rank : 75)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	100	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q13438, O00579	Gene names	OS9
Domain Architecture	No domain graphic available
Description	Protein OS-9 precursor (Amplified in osteosarcoma 9).

FOXJ3_HUMAN
NC score	0.011577 (rank : 76)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	100	Target Neighborhood Hits	177	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

TAB3_MOUSE
NC score	0.010767 (rank : 77)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	100	Target Neighborhood Hits	273	Shared Neighborhood Hits	13
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

MBD2_MOUSE
NC score	0.010541 (rank : 78)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	100	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2E1, Q811D9, Q9Z2D9	Gene names	Mbd2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2).

PML_HUMAN
NC score	0.010132 (rank : 79)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	100	Target Neighborhood Hits	248	Shared Neighborhood Hits	4
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

SYN1_HUMAN
NC score	0.009727 (rank : 80)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	100	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

TCGAP_HUMAN
NC score	0.009707 (rank : 81)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	100	Target Neighborhood Hits	872	Shared Neighborhood Hits	23
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

LNK_HUMAN
NC score	0.009521 (rank : 82)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	100	Target Neighborhood Hits	151	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQQ2, O95184	Gene names	LNK
Domain Architecture
Description	Lymphocyte-specific adapter protein Lnk (Signal transduction protein Lnk) (Lymphocyte adapter protein).

VAX2_MOUSE
NC score	0.008969 (rank : 83)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	100	Target Neighborhood Hits	338	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTP9	Gene names	Vax2, Vex
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 2 (Ventral retina homeodomain protein).

UTP20_HUMAN
NC score	0.008817 (rank : 84)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	100	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

IWS1_HUMAN
NC score	0.008185 (rank : 85)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	100	Target Neighborhood Hits	1241	Shared Neighborhood Hits	17
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SNTB2_MOUSE
NC score	0.007709 (rank : 86)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	100	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	Q61235	Gene names	Sntb2, Snt2b2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

TCF7_HUMAN
NC score	0.007530 (rank : 87)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	100	Target Neighborhood Hits	186	Shared Neighborhood Hits	11
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

SOX9_HUMAN
NC score	0.007456 (rank : 88)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	100	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_MOUSE
NC score	0.006783 (rank : 89)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	100	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

PTPRN_MOUSE
NC score	0.006763 (rank : 90)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	100	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

TJAP1_HUMAN
NC score	0.006032 (rank : 91)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	100	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

TSH2_MOUSE
NC score	0.005849 (rank : 92)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	100	Target Neighborhood Hits	467	Shared Neighborhood Hits	3
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

MILK1_HUMAN
NC score	0.005464 (rank : 93)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	100	Target Neighborhood Hits	427	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

CEBPA_MOUSE
NC score	0.005356 (rank : 94)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	100	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	P53566, Q91XB6	Gene names	Cebpa
Domain Architecture
Description	CCAAT/enhancer-binding protein alpha (C/EBP alpha).

VAX2_HUMAN
NC score	0.004796 (rank : 95)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	100	Target Neighborhood Hits	337	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIW0	Gene names	VAX2
Domain Architecture
Description	Ventral anterior homeobox 2.

NRG2_HUMAN
NC score	0.004582 (rank : 96)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	100	Target Neighborhood Hits	419	Shared Neighborhood Hits	4
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

CSKI2_MOUSE
NC score	0.003707 (rank : 97)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	100	Target Neighborhood Hits	812	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

VTNC_MOUSE
NC score	0.003662 (rank : 98)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	100	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P29788, Q8VII4	Gene names	Vtn
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein).

SIM2_HUMAN
NC score	0.003184 (rank : 99)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	100	Target Neighborhood Hits	76	Shared Neighborhood Hits	5
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

KCNC3_HUMAN
NC score	0.003125 (rank : 100)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	100	Target Neighborhood Hits	256	Shared Neighborhood Hits	8
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

WNK2_HUMAN
NC score	0.001563 (rank : 101)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	100	Target Neighborhood Hits	1407	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CSKI2_HUMAN
NC score	0.001178 (rank : 102)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	100	Target Neighborhood Hits	747	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

AMHR2_HUMAN
NC score	-0.001423 (rank : 103)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	100	Target Neighborhood Hits	715	Shared Neighborhood Hits	5
SwissProt Accessions	Q16671, Q13762	Gene names	AMHR2, AMHR
Domain Architecture
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII).

AATK_MOUSE
NC score	-0.002794 (rank : 104)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	100	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

PGBM_MOUSE
NC score	-0.003270 (rank : 105)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	100	Target Neighborhood Hits	1073	Shared Neighborhood Hits	4
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

REST_MOUSE
NC score	-0.004378 (rank : 106)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	100	Target Neighborhood Hits	1506	Shared Neighborhood Hits	8
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.