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Network neighborhood for query Sequence : SPDEF_HUMAN

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SPDEF_HUMAN
SwissProt Accessions	O95238	Gene names	SPDEF, PDEF, PSE
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPDEF_HUMAN
θ value	3.0341e-181 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	O95238	Gene names	SPDEF, PDEF, PSE
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).

SPDEF_MOUSE
θ value	5.93515e-169 (rank : 2)	NC score	0.997456 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WTP3	Gene names	Spdef, Pdef, Pse
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).

ELF5_HUMAN
θ value	1.62847e-25 (rank : 3)	NC score	0.909025 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	51	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UKW6, O95175, Q8N2K9, Q96QY3, Q9UKW5	Gene names	ELF5
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-specific Ets transcription factor 2) (ESE-2) (Epithelium- restricted ESE-1-related Ets factor).

ELF5_MOUSE
θ value	3.62785e-25 (rank : 4)	NC score	0.910345 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	50	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VDK3, Q921H5, Q9Z2K6	Gene names	Elf5
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-5 (E74-like factor 5).

GABPA_HUMAN
θ value	4.9032e-22 (rank : 5)	NC score	0.885550 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q06546, Q12939	Gene names	GABPA, E4TF1A
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha) (Transcription factor E4TF1-60) (Nuclear respiratory factor 2 subunit alpha).

GABPA_MOUSE
θ value	9.24701e-21 (rank : 6)	NC score	0.885270 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	50	Shared Neighborhood Hits	47
SwissProt Accessions	Q00422	Gene names	Gabpa, E4tf1a
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha).

ELF2_HUMAN
θ value	2.97466e-19 (rank : 7)	NC score	0.866414 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	78	Shared Neighborhood Hits	47
SwissProt Accessions	Q15723, Q15724, Q15725, Q6P1K5	Gene names	ELF2, NERF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

ELF2_MOUSE
θ value	2.97466e-19 (rank : 8)	NC score	0.867323 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	81	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JHC9, Q6NST2, Q8BTX8, Q9JHC7, Q9JHC8, Q9JHD0	Gene names	Elf2, Nerf
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

ELF1_HUMAN
θ value	3.88503e-19 (rank : 9)	NC score	0.859314 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	104	Shared Neighborhood Hits	47
SwissProt Accessions	P32519, Q9UDE1	Gene names	ELF1
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

ELF1_MOUSE
θ value	3.88503e-19 (rank : 10)	NC score	0.851675 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	139	Shared Neighborhood Hits	47
SwissProt Accessions	Q60775	Gene names	Elf1
Domain Architecture
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

ELF4_HUMAN
θ value	3.88503e-19 (rank : 11)	NC score	0.861167 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	87	Shared Neighborhood Hits	47
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

ELF4_MOUSE
θ value	3.88503e-19 (rank : 12)	NC score	0.838314 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	191	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

FLI1_MOUSE
θ value	5.07402e-19 (rank : 13)	NC score	0.855119 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P26323	Gene names	Fli1, Fli-1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Retroviral integration site protein Fli-1).

FLI1_HUMAN
θ value	6.62687e-19 (rank : 14)	NC score	0.854226 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	65	Shared Neighborhood Hits	47
SwissProt Accessions	Q01543, Q14319, Q92480, Q9UE07	Gene names	FLI1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Fli-1 proto- oncogene) (ERGB transcription factor).

ELK1_HUMAN
θ value	7.32683e-18 (rank : 15)	NC score	0.883237 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

ELK1_MOUSE
θ value	7.32683e-18 (rank : 16)	NC score	0.880975 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	110	Shared Neighborhood Hits	48
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

ELK4_HUMAN
θ value	8.10077e-17 (rank : 17)	NC score	0.855434 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	184	Shared Neighborhood Hits	47
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

ETV4_HUMAN
θ value	1.38178e-16 (rank : 18)	NC score	0.817412 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	P43268, Q96AW9	Gene names	ETV4, E1AF
Domain Architecture	No domain graphic available
Description	ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F).

ETV4_MOUSE
θ value	1.38178e-16 (rank : 19)	NC score	0.817739 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

ETV1_HUMAN
θ value	3.07829e-16 (rank : 20)	NC score	0.823961 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	107	Shared Neighborhood Hits	45
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

ETV1_MOUSE
θ value	3.07829e-16 (rank : 21)	NC score	0.824842 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	92	Shared Neighborhood Hits	45
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

ELK4_MOUSE
θ value	4.02038e-16 (rank : 22)	NC score	0.865065 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	107	Shared Neighborhood Hits	47
SwissProt Accessions	P41158	Gene names	Elk4, Sap1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

ETV5_HUMAN
θ value	6.85773e-16 (rank : 23)	NC score	0.816911 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	181	Shared Neighborhood Hits	46
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

ETV5_MOUSE
θ value	6.85773e-16 (rank : 24)	NC score	0.798750 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	328	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

ELK3_HUMAN
θ value	5.8054e-15 (rank : 25)	NC score	0.867767 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	P41970, Q6FG57, Q6GU29, Q9UD17	Gene names	ELK3, NET, SAP2
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP) (SRF accessory protein 2) (SAP-2).

ETV3_HUMAN
θ value	5.8054e-15 (rank : 26)	NC score	0.808461 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	312	Shared Neighborhood Hits	47
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ETV3_MOUSE
θ value	5.8054e-15 (rank : 27)	NC score	0.833510 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	128	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ELK3_MOUSE
θ value	9.90251e-15 (rank : 28)	NC score	0.864217 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	72	Shared Neighborhood Hits	47
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

ETS2_HUMAN
θ value	9.90251e-15 (rank : 29)	NC score	0.847519 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	P15036	Gene names	ETS2
Domain Architecture
Description	C-ets-2 protein.

ETS2_MOUSE
θ value	9.90251e-15 (rank : 30)	NC score	0.845541 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	P15037	Gene names	Ets2
Domain Architecture
Description	C-ets-2 protein.

ETS1_HUMAN
θ value	1.29331e-14 (rank : 31)	NC score	0.846254 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	49	Shared Neighborhood Hits	47
SwissProt Accessions	P14921, Q14278, Q16080	Gene names	ETS1
Domain Architecture
Description	C-ets-1 protein (p54).

ETS1_MOUSE
θ value	1.29331e-14 (rank : 32)	NC score	0.846301 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	48	Shared Neighborhood Hits	47
SwissProt Accessions	P27577, Q61403	Gene names	Ets1, Ets-1
Domain Architecture
Description	C-ets-1 protein (p54).

ETV6_HUMAN
θ value	2.20605e-14 (rank : 33)	NC score	0.834691 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	120	Shared Neighborhood Hits	48
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ETV6_MOUSE
θ value	2.20605e-14 (rank : 34)	NC score	0.836426 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	P97360	Gene names	Etv6, Tel, Tel1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ERF_HUMAN
θ value	2.88119e-14 (rank : 35)	NC score	0.831082 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	162	Shared Neighborhood Hits	47
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ERF_MOUSE
θ value	2.88119e-14 (rank : 36)	NC score	0.830544 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	160	Shared Neighborhood Hits	47
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

ETV2_HUMAN
θ value	3.18553e-13 (rank : 37)	NC score	0.866446 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	O00321, Q9UEA0	Gene names	ETV2, ER71, ETSRP71
Domain Architecture
Description	ETS translocation variant 2 (Ets-related protein 71).

ERG_MOUSE
θ value	4.16044e-13 (rank : 38)	NC score	0.831332 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	P81270, Q8C5L4, Q920K7, Q920K8, Q920K9	Gene names	Erg, Erg-3
Domain Architecture
Description	Transcriptional regulator ERG.

ERG_HUMAN
θ value	5.43371e-13 (rank : 39)	NC score	0.839816 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	86	Shared Neighborhood Hits	47
SwissProt Accessions	P11308, Q16113	Gene names	ERG
Domain Architecture
Description	Transcriptional regulator ERG (Transforming protein ERG).

ETV7_HUMAN
θ value	1.2105e-12 (rank : 40)	NC score	0.867495 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	61	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y603, Q9NZ65, Q9NZ66, Q9NZ68, Q9NZR8, Q9UNJ7, Q9Y5K4, Q9Y604	Gene names	ETV7, TEL2, TELB, TREF
Domain Architecture
Description	Transcription factor ETV7 (Transcription factor Tel-2) (ETS-related protein Tel2) (Tel-related Ets factor).

ETV2_MOUSE
θ value	1.58096e-12 (rank : 41)	NC score	0.864365 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	58	Shared Neighborhood Hits	47
SwissProt Accessions	P41163	Gene names	Etv2, Er71, Etsrp71
Domain Architecture
Description	ETS translocation variant 2 (Ets-related protein 71).

SPIC_HUMAN
θ value	1.06045e-08 (rank : 42)	NC score	0.688304 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N5J4	Gene names	SPIC
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-C.

SPI1_HUMAN
θ value	6.87365e-08 (rank : 43)	NC score	0.702445 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	P17947	Gene names	SPI1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein).

SPI1_MOUSE
θ value	6.87365e-08 (rank : 44)	NC score	0.704997 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	47	Shared Neighborhood Hits	45
SwissProt Accessions	P17433, Q99L57	Gene names	Spi1, Sfpi-1, Sfpi1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein) (SFFV proviral integration 1 protein).

SPIB_MOUSE
θ value	9.92553e-07 (rank : 45)	NC score	0.680995 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

SPIC_MOUSE
θ value	1.69304e-06 (rank : 46)	NC score	0.654980 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P3D7, Q9Z0Y0	Gene names	Spic
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-C (Pu.1-related factor) (Prf).

SPIB_HUMAN
θ value	3.77169e-06 (rank : 47)	NC score	0.685546 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q01892, Q15359	Gene names	SPIB
Domain Architecture
Description	Transcription factor Spi-B.

TXLNB_MOUSE
θ value	0.365318 (rank : 48)	NC score	0.011671 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	640	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

DNMBP_MOUSE
θ value	1.06291 (rank : 49)	NC score	0.009303 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	435	Shared Neighborhood Hits	2
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

SFR14_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.018638 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IX01, O15071, O60369, Q5JPH7, Q8WUF7	Gene names	SFRS14, KIAA0365
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

QSCN6_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.013954 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BND5, Q3TDY9, Q3TE19, Q3TR29, Q3UEL4, Q8K041, Q9DBL6	Gene names	Qscn6, Sox
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase) (mSOx).

BTBDA_MOUSE
θ value	2.36792 (rank : 52)	NC score	0.018633 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q80X66	Gene names	Btbd10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

IRF4_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.016595 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

RD23B_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.009941 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

PON3_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.005338 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q15166, O75855, O76060, Q6IRU9, Q8IX97, Q9BZH9	Gene names	PON3
Domain Architecture
Description	Serum paraoxonase/lactonase 3 (EC 3.1.1.-).

PRRT3_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.005866 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	998	Shared Neighborhood Hits	8
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

Hits sorted by NC score

SPDEF_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.0341e-181 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	O95238	Gene names	SPDEF, PDEF, PSE
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).

SPDEF_MOUSE
NC score	0.997456 (rank : 2)	θ value	5.93515e-169 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WTP3	Gene names	Spdef, Pdef, Pse
Domain Architecture	No domain graphic available
Description	SAM pointed domain-containing Ets transcription factor (Prostate- derived Ets factor) (Prostate epithelium-specific Ets transcription factor) (Prostate-specific Ets).

ELF5_MOUSE
NC score	0.910345 (rank : 3)	θ value	3.62785e-25 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	50	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VDK3, Q921H5, Q9Z2K6	Gene names	Elf5
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-5 (E74-like factor 5).

ELF5_HUMAN
NC score	0.909025 (rank : 4)	θ value	1.62847e-25 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	51	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UKW6, O95175, Q8N2K9, Q96QY3, Q9UKW5	Gene names	ELF5
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-specific Ets transcription factor 2) (ESE-2) (Epithelium- restricted ESE-1-related Ets factor).

GABPA_HUMAN
NC score	0.885550 (rank : 5)	θ value	4.9032e-22 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q06546, Q12939	Gene names	GABPA, E4TF1A
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha) (Transcription factor E4TF1-60) (Nuclear respiratory factor 2 subunit alpha).

GABPA_MOUSE
NC score	0.885270 (rank : 6)	θ value	9.24701e-21 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	50	Shared Neighborhood Hits	47
SwissProt Accessions	Q00422	Gene names	Gabpa, E4tf1a
Domain Architecture
Description	GA-binding protein alpha chain (GABP-subunit alpha).

ELK1_HUMAN
NC score	0.883237 (rank : 7)	θ value	7.32683e-18 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	P19419, O75606, O95058, Q969X8, Q9UJM4	Gene names	ELK1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

ELK1_MOUSE
NC score	0.880975 (rank : 8)	θ value	7.32683e-18 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	110	Shared Neighborhood Hits	48
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

ELK3_HUMAN
NC score	0.867767 (rank : 9)	θ value	5.8054e-15 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	P41970, Q6FG57, Q6GU29, Q9UD17	Gene names	ELK3, NET, SAP2
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP) (SRF accessory protein 2) (SAP-2).

ETV7_HUMAN
NC score	0.867495 (rank : 10)	θ value	1.2105e-12 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	61	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y603, Q9NZ65, Q9NZ66, Q9NZ68, Q9NZR8, Q9UNJ7, Q9Y5K4, Q9Y604	Gene names	ETV7, TEL2, TELB, TREF
Domain Architecture
Description	Transcription factor ETV7 (Transcription factor Tel-2) (ETS-related protein Tel2) (Tel-related Ets factor).

ELF2_MOUSE
NC score	0.867323 (rank : 11)	θ value	2.97466e-19 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	81	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JHC9, Q6NST2, Q8BTX8, Q9JHC7, Q9JHC8, Q9JHD0	Gene names	Elf2, Nerf
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

ETV2_HUMAN
NC score	0.866446 (rank : 12)	θ value	3.18553e-13 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	O00321, Q9UEA0	Gene names	ETV2, ER71, ETSRP71
Domain Architecture
Description	ETS translocation variant 2 (Ets-related protein 71).

ELF2_HUMAN
NC score	0.866414 (rank : 13)	θ value	2.97466e-19 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	78	Shared Neighborhood Hits	47
SwissProt Accessions	Q15723, Q15724, Q15725, Q6P1K5	Gene names	ELF2, NERF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

ELK4_MOUSE
NC score	0.865065 (rank : 14)	θ value	4.02038e-16 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	107	Shared Neighborhood Hits	47
SwissProt Accessions	P41158	Gene names	Elk4, Sap1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

ETV2_MOUSE
NC score	0.864365 (rank : 15)	θ value	1.58096e-12 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	58	Shared Neighborhood Hits	47
SwissProt Accessions	P41163	Gene names	Etv2, Er71, Etsrp71
Domain Architecture
Description	ETS translocation variant 2 (Ets-related protein 71).

ELK3_MOUSE
NC score	0.864217 (rank : 16)	θ value	9.90251e-15 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	72	Shared Neighborhood Hits	47
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

ELF4_HUMAN
NC score	0.861167 (rank : 17)	θ value	3.88503e-19 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	87	Shared Neighborhood Hits	47
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

ELF1_HUMAN
NC score	0.859314 (rank : 18)	θ value	3.88503e-19 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	104	Shared Neighborhood Hits	47
SwissProt Accessions	P32519, Q9UDE1	Gene names	ELF1
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

ELK4_HUMAN
NC score	0.855434 (rank : 19)	θ value	8.10077e-17 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	184	Shared Neighborhood Hits	47
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

FLI1_MOUSE
NC score	0.855119 (rank : 20)	θ value	5.07402e-19 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P26323	Gene names	Fli1, Fli-1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Retroviral integration site protein Fli-1).

FLI1_HUMAN
NC score	0.854226 (rank : 21)	θ value	6.62687e-19 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	65	Shared Neighborhood Hits	47
SwissProt Accessions	Q01543, Q14319, Q92480, Q9UE07	Gene names	FLI1
Domain Architecture
Description	Friend leukemia integration 1 transcription factor (Fli-1 proto- oncogene) (ERGB transcription factor).

ELF1_MOUSE
NC score	0.851675 (rank : 22)	θ value	3.88503e-19 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	139	Shared Neighborhood Hits	47
SwissProt Accessions	Q60775	Gene names	Elf1
Domain Architecture
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

ETS2_HUMAN
NC score	0.847519 (rank : 23)	θ value	9.90251e-15 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	P15036	Gene names	ETS2
Domain Architecture
Description	C-ets-2 protein.

ETS1_MOUSE
NC score	0.846301 (rank : 24)	θ value	1.29331e-14 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	48	Shared Neighborhood Hits	47
SwissProt Accessions	P27577, Q61403	Gene names	Ets1, Ets-1
Domain Architecture
Description	C-ets-1 protein (p54).

ETS1_HUMAN
NC score	0.846254 (rank : 25)	θ value	1.29331e-14 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	49	Shared Neighborhood Hits	47
SwissProt Accessions	P14921, Q14278, Q16080	Gene names	ETS1
Domain Architecture
Description	C-ets-1 protein (p54).

ETS2_MOUSE
NC score	0.845541 (rank : 26)	θ value	9.90251e-15 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	P15037	Gene names	Ets2
Domain Architecture
Description	C-ets-2 protein.

ERG_HUMAN
NC score	0.839816 (rank : 27)	θ value	5.43371e-13 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	86	Shared Neighborhood Hits	47
SwissProt Accessions	P11308, Q16113	Gene names	ERG
Domain Architecture
Description	Transcriptional regulator ERG (Transforming protein ERG).

ELF4_MOUSE
NC score	0.838314 (rank : 28)	θ value	3.88503e-19 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	191	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z2U4	Gene names	Elf4, Mef
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

ETV6_MOUSE
NC score	0.836426 (rank : 29)	θ value	2.20605e-14 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	P97360	Gene names	Etv6, Tel, Tel1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ETV6_HUMAN
NC score	0.834691 (rank : 30)	θ value	2.20605e-14 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	120	Shared Neighborhood Hits	48
SwissProt Accessions	P41212, Q9UMF6	Gene names	ETV6, TEL, TEL1
Domain Architecture
Description	Transcription factor ETV6 (ETS-related protein Tel1) (Tel) (ETS translocation variant 6).

ETV3_MOUSE
NC score	0.833510 (rank : 31)	θ value	5.8054e-15 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	128	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4Z4, Q9QZW1	Gene names	Etv3, Mets, Pe1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ERG_MOUSE
NC score	0.831332 (rank : 32)	θ value	4.16044e-13 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	P81270, Q8C5L4, Q920K7, Q920K8, Q920K9	Gene names	Erg, Erg-3
Domain Architecture
Description	Transcriptional regulator ERG.

ERF_HUMAN
NC score	0.831082 (rank : 33)	θ value	2.88119e-14 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	162	Shared Neighborhood Hits	47
SwissProt Accessions	P50548, Q9UPI7	Gene names	ERF
Domain Architecture
Description	ETS domain-containing transcription factor ERF (Ets2 repressor factor).

ERF_MOUSE
NC score	0.830544 (rank : 34)	θ value	2.88119e-14 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	160	Shared Neighborhood Hits	47
SwissProt Accessions	P70459	Gene names	Erf
Domain Architecture
Description	ETS domain-containing transcription factor ERF.

ETV1_MOUSE
NC score	0.824842 (rank : 35)	θ value	3.07829e-16 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	92	Shared Neighborhood Hits	45
SwissProt Accessions	P41164	Gene names	Etv1, Er81, Etsrp81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

ETV1_HUMAN
NC score	0.823961 (rank : 36)	θ value	3.07829e-16 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	107	Shared Neighborhood Hits	45
SwissProt Accessions	P50549, O75849, Q9UQ71, Q9Y636	Gene names	ETV1, ER81
Domain Architecture
Description	ETS translocation variant 1 (ER81 protein).

ETV4_MOUSE
NC score	0.817739 (rank : 37)	θ value	1.38178e-16 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	P28322	Gene names	Etv4, Pea-3, Pea3
Domain Architecture
Description	ETS translocation variant 4 (Polyomavirus enhancer activator 3) (Protein PEA3).

ETV4_HUMAN
NC score	0.817412 (rank : 38)	θ value	1.38178e-16 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	P43268, Q96AW9	Gene names	ETV4, E1AF
Domain Architecture	No domain graphic available
Description	ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F).

ETV5_HUMAN
NC score	0.816911 (rank : 39)	θ value	6.85773e-16 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	181	Shared Neighborhood Hits	46
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

ETV3_HUMAN
NC score	0.808461 (rank : 40)	θ value	5.8054e-15 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	312	Shared Neighborhood Hits	47
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ETV5_MOUSE
NC score	0.798750 (rank : 41)	θ value	6.85773e-16 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	328	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

SPI1_MOUSE
NC score	0.704997 (rank : 42)	θ value	6.87365e-08 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	47	Shared Neighborhood Hits	45
SwissProt Accessions	P17433, Q99L57	Gene names	Spi1, Sfpi-1, Sfpi1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein) (SFFV proviral integration 1 protein).

SPI1_HUMAN
NC score	0.702445 (rank : 43)	θ value	6.87365e-08 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	50	Shared Neighborhood Hits	45
SwissProt Accessions	P17947	Gene names	SPI1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein).

SPIC_HUMAN
NC score	0.688304 (rank : 44)	θ value	1.06045e-08 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q8N5J4	Gene names	SPIC
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-C.

SPIB_HUMAN
NC score	0.685546 (rank : 45)	θ value	3.77169e-06 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q01892, Q15359	Gene names	SPIB
Domain Architecture
Description	Transcription factor Spi-B.

SPIB_MOUSE
NC score	0.680995 (rank : 46)	θ value	9.92553e-07 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

SPIC_MOUSE
NC score	0.654980 (rank : 47)	θ value	1.69304e-06 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P3D7, Q9Z0Y0	Gene names	Spic
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-C (Pu.1-related factor) (Prf).

SFR14_HUMAN
NC score	0.018638 (rank : 48)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IX01, O15071, O60369, Q5JPH7, Q8WUF7	Gene names	SFRS14, KIAA0365
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

BTBDA_MOUSE
NC score	0.018633 (rank : 49)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q80X66	Gene names	Btbd10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

IRF4_MOUSE
NC score	0.016595 (rank : 50)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q64287, Q60802	Gene names	Irf4, Spip
Domain Architecture
Description	Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (NF-EM5) (PU.1 interaction partner) (Transcriptional activator PIP).

QSCN6_MOUSE
NC score	0.013954 (rank : 51)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BND5, Q3TDY9, Q3TE19, Q3TR29, Q3UEL4, Q8K041, Q9DBL6	Gene names	Qscn6, Sox
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase) (mSOx).

TXLNB_MOUSE
NC score	0.011671 (rank : 52)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	640	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VBT1, Q3UVB8, Q8BUK2	Gene names	Txlnb, Mdp77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77).

RD23B_MOUSE
NC score	0.009941 (rank : 53)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

DNMBP_MOUSE
NC score	0.009303 (rank : 54)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	435	Shared Neighborhood Hits	2
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

PRRT3_HUMAN
NC score	0.005866 (rank : 55)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	998	Shared Neighborhood Hits	8
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PON3_HUMAN
NC score	0.005338 (rank : 56)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q15166, O75855, O76060, Q6IRU9, Q8IX97, Q9BZH9	Gene names	PON3
Domain Architecture
Description	Serum paraoxonase/lactonase 3 (EC 3.1.1.-).