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Network neighborhood for query Sequence : CPSF3_HUMAN

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CPSF3_HUMAN
SwissProt Accessions	Q9UKF6, O14769, Q96F36	Gene names	CPSF3, CPSF73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CPSF3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKF6, O14769, Q96F36	Gene names	CPSF3, CPSF73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).

CPSF3_MOUSE
θ value	0 (rank : 2)	NC score	0.999455 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXK7	Gene names	Cpsf3, Cpsf73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).

CPSF2_MOUSE
θ value	2.77131e-33 (rank : 3)	NC score	0.701958 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	O35218	Gene names	Cpsf2, Cpsf100, Mcpsf
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

CPSF2_HUMAN
θ value	3.61944e-33 (rank : 4)	NC score	0.701064 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2I0, Q6NSJ1, Q9H3W7	Gene names	CPSF2, CPSF100, KIAA1367
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

NTRK1_HUMAN
θ value	0.0330416 (rank : 5)	NC score	0.016281 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	1023	Shared Neighborhood Hits	3
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

ITSN2_MOUSE
θ value	0.365318 (rank : 6)	NC score	0.028532 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	1371	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

RNZ1_HUMAN
θ value	1.81305 (rank : 7)	NC score	0.065656 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H777, Q9NS99	Gene names	ELAC1, D29
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (Ribonuclease Z 1) (RNase Z 1) (tRNase Z 1) (tRNA 3 endonuclease 1) (ElaC homolog protein 1) (Deleted in Ma29).

ITSN2_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.019176 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	1173	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

RNZ1_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.062531 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VEB6, Q9CXB1, Q9ERF4	Gene names	Elac1
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (Ribonuclease Z 1) (RNase Z 1) (tRNase Z 1) (tRNA 3 endonuclease 1) (ElaC homolog protein 1).

PO210_MOUSE
θ value	3.0926 (rank : 10)	NC score	0.017620 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY81, Q3U031, Q69ZW2, Q7TQM1	Gene names	Nup210, Kiaa0906
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210 precursor (POM210) (Nuclear pore protein gp210).

VHL_MOUSE
θ value	6.88961 (rank : 11)	NC score	0.021683 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P40338	Gene names	Vhl, Vhlh
Domain Architecture
Description	Von Hippel-Lindau disease tumor suppressor (pVHL).

K0179_HUMAN
θ value	8.99809 (rank : 12)	NC score	0.013411 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q14684, Q8TBZ4	Gene names	KIAA0179
Domain Architecture
Description	Protein KIAA0179.

UTP20_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.011586 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

Hits sorted by NC score

CPSF3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKF6, O14769, Q96F36	Gene names	CPSF3, CPSF73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).

CPSF3_MOUSE
NC score	0.999455 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXK7	Gene names	Cpsf3, Cpsf73
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 73 kDa subunit (CPSF 73 kDa subunit).

CPSF2_MOUSE
NC score	0.701958 (rank : 3)	θ value	2.77131e-33 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	O35218	Gene names	Cpsf2, Cpsf100, Mcpsf
Domain Architecture
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

CPSF2_HUMAN
NC score	0.701064 (rank : 4)	θ value	3.61944e-33 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2I0, Q6NSJ1, Q9H3W7	Gene names	CPSF2, CPSF100, KIAA1367
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit).

RNZ1_HUMAN
NC score	0.065656 (rank : 5)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H777, Q9NS99	Gene names	ELAC1, D29
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (Ribonuclease Z 1) (RNase Z 1) (tRNase Z 1) (tRNA 3 endonuclease 1) (ElaC homolog protein 1) (Deleted in Ma29).

RNZ1_MOUSE
NC score	0.062531 (rank : 6)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VEB6, Q9CXB1, Q9ERF4	Gene names	Elac1
Domain Architecture
Description	Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (Ribonuclease Z 1) (RNase Z 1) (tRNase Z 1) (tRNA 3 endonuclease 1) (ElaC homolog protein 1).

ITSN2_MOUSE
NC score	0.028532 (rank : 7)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	1371	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

VHL_MOUSE
NC score	0.021683 (rank : 8)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	P40338	Gene names	Vhl, Vhlh
Domain Architecture
Description	Von Hippel-Lindau disease tumor suppressor (pVHL).

ITSN2_HUMAN
NC score	0.019176 (rank : 9)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	1173	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

PO210_MOUSE
NC score	0.017620 (rank : 10)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY81, Q3U031, Q69ZW2, Q7TQM1	Gene names	Nup210, Kiaa0906
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210 precursor (POM210) (Nuclear pore protein gp210).

NTRK1_HUMAN
NC score	0.016281 (rank : 11)	θ value	0.0330416 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	1023	Shared Neighborhood Hits	3
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

K0179_HUMAN
NC score	0.013411 (rank : 12)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q14684, Q8TBZ4	Gene names	KIAA0179
Domain Architecture
Description	Protein KIAA0179.

UTP20_HUMAN
NC score	0.011586 (rank : 13)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).