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Network neighborhood for query Sequence : HEAT2_HUMAN

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HEAT2_HUMAN
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HEAT2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

GCN1L_HUMAN
θ value	9.29e-05 (rank : 2)	NC score	0.259549 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

2AAB_MOUSE
θ value	0.00298849 (rank : 3)	NC score	0.216530 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_HUMAN
θ value	0.00390308 (rank : 4)	NC score	0.217558 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

SF3B1_HUMAN
θ value	0.0736092 (rank : 5)	NC score	0.147460 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	341	Shared Neighborhood Hits	16
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.0736092 (rank : 6)	NC score	0.147331 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

2AAA_HUMAN
θ value	0.163984 (rank : 7)	NC score	0.195257 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	42	Shared Neighborhood Hits	12
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
θ value	0.163984 (rank : 8)	NC score	0.195645 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

ECM29_HUMAN
θ value	0.163984 (rank : 9)	NC score	0.121634 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VYK3, O15074, Q8WU82	Gene names	ECM29, KIAA0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

MMS19_MOUSE
θ value	0.21417 (rank : 10)	NC score	0.114289 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D071, Q925N8, Q9CWX3	Gene names	Mms19l, Mms19
Domain Architecture	No domain graphic available
Description	MMS19-like protein (MET18 homolog).

LAMC3_MOUSE
θ value	0.62314 (rank : 11)	NC score	0.018484 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	624	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MMS19_HUMAN
θ value	0.62314 (rank : 12)	NC score	0.104934 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q96T76, Q5T455, Q66K82, Q7L4W8, Q969Z1, Q96DF1, Q96MR1, Q96RK5, Q96SK1, Q9BUE2, Q9BYS9	Gene names	MMS19L, MMS19
Domain Architecture	No domain graphic available
Description	MMS19-like protein (hMMS19) (MET18 homolog).

TNPO2_HUMAN
θ value	0.62314 (rank : 13)	NC score	0.104889 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	0.62314 (rank : 14)	NC score	0.106551 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

ECM29_MOUSE
θ value	0.813845 (rank : 15)	NC score	0.111866 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

CLPP_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.065522 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q16740	Gene names	CLPP
Domain Architecture
Description	Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial precursor (EC 3.4.21.92) (Endopeptidase Clp).

FRAP_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.056706 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	77	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

RNF31_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.039820 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

TNR8_MOUSE
θ value	1.38821 (rank : 19)	NC score	0.046563 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	208	Shared Neighborhood Hits	2
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNPO1_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.102646 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.103132 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TRRAP_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.037232 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

DYXC1_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.027884 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

IMB3_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.059572 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.059878 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

SEPT9_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.012830 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	706	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CI096_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.007495 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NE28, Q5T8U8	Gene names	C9orf96
Domain Architecture	No domain graphic available
Description	Protein kinase-like protein C9orf96.

FRAP_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.049967 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

ORC3_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.028906 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBD5, Q13565, Q6IUY7, Q9UG44, Q9UNT6	Gene names	ORC3L, LATHEO
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

ERG1_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.025271 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q14534, Q9UEK6	Gene names	SQLE, ERG1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).

HAPIP_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.012864 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	350	Shared Neighborhood Hits	3
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

KPCD2_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.001851 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	910	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

ZN318_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.017531 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	642	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

MY18A_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.002136 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	1989	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

UN45A_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.013436 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

UTP20_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.017319 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

IMB1_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.054467 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

IMB1_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.055184 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

Hits sorted by NC score

HEAT2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

GCN1L_HUMAN
NC score	0.259549 (rank : 2)	θ value	9.29e-05 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

2AAB_HUMAN
NC score	0.217558 (rank : 3)	θ value	0.00390308 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_MOUSE
NC score	0.216530 (rank : 4)	θ value	0.00298849 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAA_MOUSE
NC score	0.195645 (rank : 5)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAA_HUMAN
NC score	0.195257 (rank : 6)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	42	Shared Neighborhood Hits	12
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

SF3B1_HUMAN
NC score	0.147460 (rank : 7)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	341	Shared Neighborhood Hits	16
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.147331 (rank : 8)	θ value	0.0736092 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

ECM29_HUMAN
NC score	0.121634 (rank : 9)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VYK3, O15074, Q8WU82	Gene names	ECM29, KIAA0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

MMS19_MOUSE
NC score	0.114289 (rank : 10)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D071, Q925N8, Q9CWX3	Gene names	Mms19l, Mms19
Domain Architecture	No domain graphic available
Description	MMS19-like protein (MET18 homolog).

ECM29_MOUSE
NC score	0.111866 (rank : 11)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	65	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

TNPO2_MOUSE
NC score	0.106551 (rank : 12)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

MMS19_HUMAN
NC score	0.104934 (rank : 13)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q96T76, Q5T455, Q66K82, Q7L4W8, Q969Z1, Q96DF1, Q96MR1, Q96RK5, Q96SK1, Q9BUE2, Q9BYS9	Gene names	MMS19L, MMS19
Domain Architecture	No domain graphic available
Description	MMS19-like protein (hMMS19) (MET18 homolog).

TNPO2_HUMAN
NC score	0.104889 (rank : 14)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO1_MOUSE
NC score	0.103132 (rank : 15)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO1_HUMAN
NC score	0.102646 (rank : 16)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

CLPP_HUMAN
NC score	0.065522 (rank : 17)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q16740	Gene names	CLPP
Domain Architecture
Description	Putative ATP-dependent Clp protease proteolytic subunit, mitochondrial precursor (EC 3.4.21.92) (Endopeptidase Clp).

IMB3_MOUSE
NC score	0.059878 (rank : 18)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_HUMAN
NC score	0.059572 (rank : 19)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

FRAP_MOUSE
NC score	0.056706 (rank : 20)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	77	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

IMB1_MOUSE
NC score	0.055184 (rank : 21)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

IMB1_HUMAN
NC score	0.054467 (rank : 22)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

FRAP_HUMAN
NC score	0.049967 (rank : 23)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

TNR8_MOUSE
NC score	0.046563 (rank : 24)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	208	Shared Neighborhood Hits	2
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

RNF31_HUMAN
NC score	0.039820 (rank : 25)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

TRRAP_HUMAN
NC score	0.037232 (rank : 26)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

ORC3_HUMAN
NC score	0.028906 (rank : 27)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBD5, Q13565, Q6IUY7, Q9UG44, Q9UNT6	Gene names	ORC3L, LATHEO
Domain Architecture
Description	Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo).

DYXC1_MOUSE
NC score	0.027884 (rank : 28)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

ERG1_HUMAN
NC score	0.025271 (rank : 29)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q14534, Q9UEK6	Gene names	SQLE, ERG1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).

LAMC3_MOUSE
NC score	0.018484 (rank : 30)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	624	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

ZN318_MOUSE
NC score	0.017531 (rank : 31)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	642	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

UTP20_HUMAN
NC score	0.017319 (rank : 32)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	3
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

UN45A_HUMAN
NC score	0.013436 (rank : 33)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

HAPIP_HUMAN
NC score	0.012864 (rank : 34)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	350	Shared Neighborhood Hits	3
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

SEPT9_HUMAN
NC score	0.012830 (rank : 35)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	706	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CI096_HUMAN
NC score	0.007495 (rank : 36)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	821	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NE28, Q5T8U8	Gene names	C9orf96
Domain Architecture	No domain graphic available
Description	Protein kinase-like protein C9orf96.

MY18A_MOUSE
NC score	0.002136 (rank : 37)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	1989	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

KPCD2_HUMAN
NC score	0.001851 (rank : 38)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	910	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).