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Network neighborhood for query Sequence : ERG1_HUMAN

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ERG1_HUMAN
SwissProt Accessions	Q14534, Q9UEK6	Gene names	SQLE, ERG1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ERG1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q14534, Q9UEK6	Gene names	SQLE, ERG1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).

ERG1_MOUSE
θ value	0 (rank : 2)	NC score	0.994500 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	P52019	Gene names	Sqle, Erg1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).

OXLA_HUMAN
θ value	0.0961366 (rank : 3)	NC score	0.149275 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

KMO_HUMAN
θ value	0.163984 (rank : 4)	NC score	0.100234 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	O15229, Q5SY07, Q5SY08, Q5SY09	Gene names	KMO
Domain Architecture	No domain graphic available
Description	Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase).

OXLA_MOUSE
θ value	0.279714 (rank : 5)	NC score	0.135881 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

AOF1_HUMAN
θ value	0.365318 (rank : 6)	NC score	0.069695 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_MOUSE
θ value	0.365318 (rank : 7)	NC score	0.069934 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

CM007_MOUSE
θ value	1.06291 (rank : 8)	NC score	0.043105 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	416	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DLDH_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.054939 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	P09622, Q14131, Q14167	Gene names	DLD, GCSL, LAD, PHE3
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein).

DLDH_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.054989 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	35	Shared Neighborhood Hits	10
SwissProt Accessions	O08749	Gene names	Dld
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase).

RETST_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.076680 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NUM9, Q53R95, Q53SA9, Q6UX05, Q8N2H5, Q96FA4, Q9NXE5	Gene names	RETSAT
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

RETST_MOUSE
θ value	2.36792 (rank : 12)	NC score	0.075771 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q64FW2, Q3UNN9, Q78JX8, Q8VHE7, Q9CW85	Gene names	Retsat
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

CM007_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.037001 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	422	Shared Neighborhood Hits	3
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

MUC2_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.009049 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	906	Shared Neighborhood Hits	3
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

HEAT2_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.025271 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

K0586_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.018760 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	311	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

COQ6_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.026049 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2Z9, Q96CA1, Q96CK2	Gene names	COQ6
Domain Architecture
Description	Ubiquinone biosynthesis monooxygenase COQ6 (EC 1.14.13.-).

COQ6_MOUSE
θ value	8.99809 (rank : 18)	NC score	0.026155 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1S0	Gene names	Coq6
Domain Architecture
Description	Ubiquinone biosynthesis monooxygenase COQ6 (EC 1.14.13.-).

PLK1_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.000538 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	849	Shared Neighborhood Hits	2
SwissProt Accessions	Q07832	Gene names	Plk1, Plk
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).

Hits sorted by NC score

ERG1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	Q14534, Q9UEK6	Gene names	SQLE, ERG1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).

ERG1_MOUSE
NC score	0.994500 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	P52019	Gene names	Sqle, Erg1
Domain Architecture
Description	Squalene monooxygenase (EC 1.14.99.7) (Squalene epoxidase) (SE).

OXLA_HUMAN
NC score	0.149275 (rank : 3)	θ value	0.0961366 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RQ9, Q4GZN1, Q4GZN2, Q6P2Q3, Q8TEM5, Q96RQ8	Gene names	IL4I1, FIG1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (hFIG1).

OXLA_MOUSE
NC score	0.135881 (rank : 4)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	O09046, Q3T9N9, Q3U7S6, Q3V0K2, Q6Y632, Q6YBV6, Q6YDI8, Q8R2G8, Q9CXK7	Gene names	Il4i1, Fig1
Domain Architecture
Description	L-amino-acid oxidase precursor (EC 1.4.3.2) (LAAO) (Interleukin-4- induced protein 1) (IL4-induced protein 1) (Protein Fig-1) (mFIG1).

KMO_HUMAN
NC score	0.100234 (rank : 5)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	O15229, Q5SY07, Q5SY08, Q5SY09	Gene names	KMO
Domain Architecture	No domain graphic available
Description	Kynurenine 3-monooxygenase (EC 1.14.13.9) (Kynurenine 3-hydroxylase).

RETST_HUMAN
NC score	0.076680 (rank : 6)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NUM9, Q53R95, Q53SA9, Q6UX05, Q8N2H5, Q96FA4, Q9NXE5	Gene names	RETSAT
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

RETST_MOUSE
NC score	0.075771 (rank : 7)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q64FW2, Q3UNN9, Q78JX8, Q8VHE7, Q9CW85	Gene names	Retsat
Domain Architecture	No domain graphic available
Description	All-trans-retinol 13,14-reductase precursor (EC 1.3.99.23) (All-trans- 13,14-dihydroretinol saturase) (RetSat).

AOF1_MOUSE
NC score	0.069934 (rank : 8)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

AOF1_HUMAN
NC score	0.069695 (rank : 9)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NB78, Q5TGV3, Q6AI15, Q6ZUU4, Q8N258, Q96EL7	Gene names	AOF1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

DLDH_MOUSE
NC score	0.054989 (rank : 10)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	35	Shared Neighborhood Hits	10
SwissProt Accessions	O08749	Gene names	Dld
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase).

DLDH_HUMAN
NC score	0.054939 (rank : 11)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	P09622, Q14131, Q14167	Gene names	DLD, GCSL, LAD, PHE3
Domain Architecture
Description	Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein).

CM007_MOUSE
NC score	0.043105 (rank : 12)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	416	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

CM007_HUMAN
NC score	0.037001 (rank : 13)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	422	Shared Neighborhood Hits	3
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

COQ6_MOUSE
NC score	0.026155 (rank : 14)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R1S0	Gene names	Coq6
Domain Architecture
Description	Ubiquinone biosynthesis monooxygenase COQ6 (EC 1.14.13.-).

COQ6_HUMAN
NC score	0.026049 (rank : 15)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2Z9, Q96CA1, Q96CK2	Gene names	COQ6
Domain Architecture
Description	Ubiquinone biosynthesis monooxygenase COQ6 (EC 1.14.13.-).

HEAT2_HUMAN
NC score	0.025271 (rank : 16)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

K0586_HUMAN
NC score	0.018760 (rank : 17)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	311	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

MUC2_HUMAN
NC score	0.009049 (rank : 18)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	906	Shared Neighborhood Hits	3
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PLK1_MOUSE
NC score	0.000538 (rank : 19)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	849	Shared Neighborhood Hits	2
SwissProt Accessions	Q07832	Gene names	Plk1, Plk
Domain Architecture
Description	Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13).