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Network neighborhood for query Sequence : 2AAA_MOUSE

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2AAA_MOUSE
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

2AAA_HUMAN
θ value	0 (rank : 1)	NC score	0.999359 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	42	Shared Neighborhood Hits	40
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAB_HUMAN
θ value	0 (rank : 3)	NC score	0.989286 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_MOUSE
θ value	0 (rank : 4)	NC score	0.992600 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

PP4R1_HUMAN
θ value	2.43908e-13 (rank : 5)	NC score	0.466871 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4R1_MOUSE
θ value	6.00763e-12 (rank : 6)	NC score	0.455110 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4RL_HUMAN
θ value	7.84624e-12 (rank : 7)	NC score	0.494141 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

GCN1L_HUMAN
θ value	4.45536e-07 (rank : 8)	NC score	0.309525 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

SF3B1_HUMAN
θ value	8.40245e-06 (rank : 9)	NC score	0.251891 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	8.40245e-06 (rank : 10)	NC score	0.250390 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

PI3R4_MOUSE
θ value	0.00035302 (rank : 11)	NC score	0.141009 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	535	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

IMB1_MOUSE
θ value	0.00298849 (rank : 12)	NC score	0.184466 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

IMB1_HUMAN
θ value	0.00390308 (rank : 13)	NC score	0.180612 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

PI3R4_HUMAN
θ value	0.00665767 (rank : 14)	NC score	0.141140 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

CAND2_MOUSE
θ value	0.0252991 (rank : 15)	NC score	0.081100 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

TNPO1_HUMAN
θ value	0.0563607 (rank : 16)	NC score	0.111645 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

STK36_HUMAN
θ value	0.0736092 (rank : 17)	NC score	0.011123 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	896	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

TNPO1_MOUSE
θ value	0.0736092 (rank : 18)	NC score	0.112643 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

CAND2_HUMAN
θ value	0.0961366 (rank : 19)	NC score	0.079142 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

HD_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.109295 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

HD_MOUSE
θ value	0.163984 (rank : 21)	NC score	0.075300 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

HEAT2_HUMAN
θ value	0.163984 (rank : 22)	NC score	0.195645 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

K0423_MOUSE
θ value	0.365318 (rank : 23)	NC score	0.110001 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

NTKL_MOUSE
θ value	0.47712 (rank : 24)	NC score	0.052801 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

PCIF1_HUMAN
θ value	0.47712 (rank : 25)	NC score	0.088521 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

IPO4_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.067482 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

K0423_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.098766 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

SPC25_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.032206 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	241	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UA16, Q9D021, Q9D1K6	Gene names	Spbc25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25.

NTKL_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.056853 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

PCIF1_MOUSE
θ value	1.06291 (rank : 30)	NC score	0.078671 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	P59114	Gene names	Pcif1
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

TNPO2_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.103330 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

RTDR1_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.125107 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

IMA5_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.020783 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

O13C3_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.000153 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	690	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NGS6, Q5VVG1	Gene names	OR13C3
Domain Architecture
Description	Olfactory receptor 13C3.

PACE1_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.052151 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

BTAF1_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.011416 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

GPR85_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.004638 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	863	Shared Neighborhood Hits	4
SwissProt Accessions	P60893, Q9JHI6, Q9NPD1	Gene names	GPR85, SREB2
Domain Architecture
Description	Probable G-protein coupled receptor 85 (Super conserved receptor expressed in brain 2).

GPR85_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.004638 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	863	Shared Neighborhood Hits	4
SwissProt Accessions	P60894, Q9JHI6, Q9NPD1	Gene names	Gpr85, Sreb2
Domain Architecture
Description	Probable G-protein coupled receptor 85 (Super conserved receptor expressed in brain 2).

PACE1_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.047057 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PLAP_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.008312 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	261	Shared Neighborhood Hits	5
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

TNPO2_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.090636 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

HEAT1_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.058722 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

Hits sorted by NC score

2AAA_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAA_HUMAN
NC score	0.999359 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	42	Shared Neighborhood Hits	40
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAB_MOUSE
NC score	0.992600 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_HUMAN
NC score	0.989286 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

PP4RL_HUMAN
NC score	0.494141 (rank : 5)	θ value	7.84624e-12 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

PP4R1_HUMAN
NC score	0.466871 (rank : 6)	θ value	2.43908e-13 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4R1_MOUSE
NC score	0.455110 (rank : 7)	θ value	6.00763e-12 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	94	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

GCN1L_HUMAN
NC score	0.309525 (rank : 8)	θ value	4.45536e-07 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

SF3B1_HUMAN
NC score	0.251891 (rank : 9)	θ value	8.40245e-06 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.250390 (rank : 10)	θ value	8.40245e-06 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

HEAT2_HUMAN
NC score	0.195645 (rank : 11)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q86Y56, Q69YL1, Q96FI9, Q9NX75	Gene names	HEATR2
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 2.

IMB1_MOUSE
NC score	0.184466 (rank : 12)	θ value	0.00298849 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

IMB1_HUMAN
NC score	0.180612 (rank : 13)	θ value	0.00390308 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	51	Shared Neighborhood Hits	16
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

PI3R4_HUMAN
NC score	0.141140 (rank : 14)	θ value	0.00665767 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	534	Shared Neighborhood Hits	11
SwissProt Accessions	Q99570	Gene names	PIK3R4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein).

PI3R4_MOUSE
NC score	0.141009 (rank : 15)	θ value	0.00035302 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	535	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VD65, Q56A65, Q8C948, Q8C9D7, Q9CVC5	Gene names	Pik3r4
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 4 (EC 2.7.11.1) (PI3- kinase regulatory subunit 4).

RTDR1_HUMAN
NC score	0.125107 (rank : 16)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHP6	Gene names	RTDR1
Domain Architecture
Description	Rhabdoid tumor deletion region protein 1.

TNPO1_MOUSE
NC score	0.112643 (rank : 17)	θ value	0.0736092 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	63	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO1_HUMAN
NC score	0.111645 (rank : 18)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

K0423_MOUSE
NC score	0.110001 (rank : 19)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

HD_HUMAN
NC score	0.109295 (rank : 20)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

TNPO2_MOUSE
NC score	0.103330 (rank : 21)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

K0423_HUMAN
NC score	0.098766 (rank : 22)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

TNPO2_HUMAN
NC score	0.090636 (rank : 23)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

PCIF1_HUMAN
NC score	0.088521 (rank : 24)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4Z3, Q9NT85	Gene names	PCIF1, C20orf67
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

CAND2_MOUSE
NC score	0.081100 (rank : 25)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

CAND2_HUMAN
NC score	0.079142 (rank : 26)	θ value	0.0961366 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

PCIF1_MOUSE
NC score	0.078671 (rank : 27)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	P59114	Gene names	Pcif1
Domain Architecture
Description	Phosphorylated CTD-interacting factor 1.

HD_MOUSE
NC score	0.075300 (rank : 28)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	116	Shared Neighborhood Hits	8
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

IPO4_HUMAN
NC score	0.067482 (rank : 29)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

HEAT1_HUMAN
NC score	0.058722 (rank : 30)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

NTKL_HUMAN
NC score	0.056853 (rank : 31)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	266	Shared Neighborhood Hits	9
SwissProt Accessions	Q96KG9, Q96G50, Q96KG8, Q96KH1, Q9HAW5, Q9HBL3, Q9NR53	Gene names	SCYL1, GKLP, NTKL, TAPK, TEIF, TRAP
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (Teratoma- associated tyrosine kinase) (Telomerase transcriptional element- interacting factor) (Telomerase regulation-associated protein).

NTKL_MOUSE
NC score	0.052801 (rank : 32)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EQC5, Q3TST7, Q3UKU0, Q8K222	Gene names	Scyl1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like protein (SCY1-like protein 1) (105 kDa kinase- like protein) (Mitosis-associated kinase-like protein NTKL).

PACE1_HUMAN
NC score	0.052151 (rank : 33)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZE3, Q5THA6, Q5THA8, Q8IZN9, Q96C56, Q9UBK6	Gene names	SCYL3, PACE1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

PACE1_MOUSE
NC score	0.047057 (rank : 34)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DBQ7, Q6NY01, Q8BQC9, Q8BRJ1	Gene names	Scyl3, Pace1
Domain Architecture	No domain graphic available
Description	Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin- binding protein PACE-1) (SCY1-like protein 3).

SPC25_MOUSE
NC score	0.032206 (rank : 35)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	241	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UA16, Q9D021, Q9D1K6	Gene names	Spbc25
Domain Architecture	No domain graphic available
Description	Kinetochore protein Spc25.

IMA5_HUMAN
NC score	0.020783 (rank : 36)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	O15131	Gene names	KPNA5
Domain Architecture
Description	Importin alpha-6 subunit (Karyopherin alpha-5 subunit).

BTAF1_HUMAN
NC score	0.011416 (rank : 37)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	97	Shared Neighborhood Hits	12
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

STK36_HUMAN
NC score	0.011123 (rank : 38)	θ value	0.0736092 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	896	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

PLAP_MOUSE
NC score	0.008312 (rank : 39)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	261	Shared Neighborhood Hits	5
SwissProt Accessions	P27612, Q8C6C4	Gene names	Plaa, Plap
Domain Architecture
Description	Phospholipase A-2-activating protein (PLAP).

GPR85_HUMAN
NC score	0.004638 (rank : 40)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	863	Shared Neighborhood Hits	4
SwissProt Accessions	P60893, Q9JHI6, Q9NPD1	Gene names	GPR85, SREB2
Domain Architecture
Description	Probable G-protein coupled receptor 85 (Super conserved receptor expressed in brain 2).

GPR85_MOUSE
NC score	0.004638 (rank : 41)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	863	Shared Neighborhood Hits	4
SwissProt Accessions	P60894, Q9JHI6, Q9NPD1	Gene names	Gpr85, Sreb2
Domain Architecture
Description	Probable G-protein coupled receptor 85 (Super conserved receptor expressed in brain 2).

O13C3_HUMAN
NC score	0.000153 (rank : 42)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	690	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NGS6, Q5VVG1	Gene names	OR13C3
Domain Architecture
Description	Olfactory receptor 13C3.