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Network neighborhood for query Sequence : PP4RL_HUMAN

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PP4RL_HUMAN
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PP4RL_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

PP4R1_HUMAN
θ value	1.33454e-136 (rank : 2)	NC score	0.960311 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4R1_MOUSE
θ value	3.88293e-136 (rank : 3)	NC score	0.950741 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

2AAA_HUMAN
θ value	7.84624e-12 (rank : 4)	NC score	0.492894 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
θ value	7.84624e-12 (rank : 5)	NC score	0.494141 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAB_MOUSE
θ value	3.64472e-09 (rank : 6)	NC score	0.475810 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_HUMAN
θ value	6.21693e-09 (rank : 7)	NC score	0.469704 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

TNPO1_HUMAN
θ value	0.0113563 (rank : 8)	NC score	0.086644 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	0.0961366 (rank : 9)	NC score	0.081612 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

BL1S3_MOUSE
θ value	1.81305 (rank : 10)	NC score	0.046470 (rank : 18)
Query Neighborhood Hits	15	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U5M8, Q8C6R4, Q8R0Z3	Gene names	Bloc1s3, Blos3, Rp
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (Reduced pigmentation protein) (BLOC subunit 3).

ULK1_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.001967 (rank : 23)
Query Neighborhood Hits	15	Target Neighborhood Hits	1121	Shared Neighborhood Hits	2
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

TCPD_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.017676 (rank : 20)
Query Neighborhood Hits	15	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPD_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.016916 (rank : 21)
Query Neighborhood Hits	15	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

HD_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.035944 (rank : 19)
Query Neighborhood Hits	15	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

T22D2_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.016174 (rank : 22)
Query Neighborhood Hits	15	Target Neighborhood Hits	250	Shared Neighborhood Hits	3
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

CI040_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.054834 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXQ3, Q9NWD3	Gene names	C9orf40
Domain Architecture	No domain graphic available
Description	Protein C9orf40.

CI040_MOUSE
θ value	θ > 10 (rank : 17)	NC score	0.050786 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCE4, Q8BJJ5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf40 homolog.

GCN1L_HUMAN
θ value	θ > 10 (rank : 18)	NC score	0.070398 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

IMB1_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.052195 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

IMB1_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.053470 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

SF3B1_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.050022 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	341	Shared Neighborhood Hits	8
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

TNPO2_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.056028 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	θ > 10 (rank : 23)	NC score	0.060120 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

Hits sorted by NC score

PP4RL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9P1A2, Q9BZ17, Q9BZ18	Gene names	PPP4R1L, C20orf192
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1-like.

PP4R1_HUMAN
NC score	0.960311 (rank : 2)	θ value	1.33454e-136 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	50	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TF05, Q99774, Q9UNQ7	Gene names	PPP4R1, MEG1, PP4R1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

PP4R1_MOUSE
NC score	0.950741 (rank : 3)	θ value	3.88293e-136 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K2V1, Q8R0R8	Gene names	Ppp4r1
Domain Architecture
Description	Serine/threonine-protein phosphatase 4 regulatory subunit 1.

2AAA_MOUSE
NC score	0.494141 (rank : 4)	θ value	7.84624e-12 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

2AAA_HUMAN
NC score	0.492894 (rank : 5)	θ value	7.84624e-12 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAB_MOUSE
NC score	0.475810 (rank : 6)	θ value	3.64472e-09 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TNP2	Gene names	Ppp2r1b
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

2AAB_HUMAN
NC score	0.469704 (rank : 7)	θ value	6.21693e-09 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	P30154, O75620	Gene names	PPP2R1B
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A, subunit A, PR65-beta isoform) (PP2A, subunit A, R1-beta isoform).

TNPO1_HUMAN
NC score	0.086644 (rank : 8)	θ value	0.0113563 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
NC score	0.081612 (rank : 9)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

GCN1L_HUMAN
NC score	0.070398 (rank : 10)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	15	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

TNPO2_MOUSE
NC score	0.060120 (rank : 11)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	15	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_HUMAN
NC score	0.056028 (rank : 12)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	15	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

CI040_HUMAN
NC score	0.054834 (rank : 13)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IXQ3, Q9NWD3	Gene names	C9orf40
Domain Architecture	No domain graphic available
Description	Protein C9orf40.

IMB1_MOUSE
NC score	0.053470 (rank : 14)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	15	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

IMB1_HUMAN
NC score	0.052195 (rank : 15)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	15	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

CI040_MOUSE
NC score	0.050786 (rank : 16)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCE4, Q8BJJ5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf40 homolog.

SF3B1_HUMAN
NC score	0.050022 (rank : 17)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	15	Target Neighborhood Hits	341	Shared Neighborhood Hits	8
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

BL1S3_MOUSE
NC score	0.046470 (rank : 18)	θ value	1.81305 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5U5M8, Q8C6R4, Q8R0Z3	Gene names	Bloc1s3, Blos3, Rp
Domain Architecture	No domain graphic available
Description	Biogenesis of lysosome-related organelles complex-1 subunit 3 (Reduced pigmentation protein) (BLOC subunit 3).

HD_HUMAN
NC score	0.035944 (rank : 19)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

TCPD_MOUSE
NC score	0.017676 (rank : 20)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P80315	Gene names	Cct4, Cctd
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (A45).

TCPD_HUMAN
NC score	0.016916 (rank : 21)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P50991, O14870, Q96C51	Gene names	CCT4, CCTD, SRB
Domain Architecture
Description	T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding).

T22D2_HUMAN
NC score	0.016174 (rank : 22)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	250	Shared Neighborhood Hits	3
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

ULK1_HUMAN
NC score	0.001967 (rank : 23)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	1121	Shared Neighborhood Hits	2
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).