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Network neighborhood for query Sequence : ATR_MOUSE

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ATR_MOUSE
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ATR_HUMAN
θ value	0 (rank : 1)	NC score	0.996814 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	Q13535, Q7KYL3, Q93051, Q9BXK4	Gene names	ATR, FRP1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).

ATR_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

ATM_HUMAN
θ value	1.18549e-84 (rank : 3)	NC score	0.806565 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	78	Shared Neighborhood Hits	32
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

ATM_MOUSE
θ value	2.64101e-84 (rank : 4)	NC score	0.812630 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q62388	Gene names	Atm
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T, mutated homolog).

FRAP_MOUSE
θ value	1.61718e-49 (rank : 5)	NC score	0.762427 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	77	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
θ value	8.02596e-49 (rank : 6)	NC score	0.761111 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	83	Shared Neighborhood Hits	32
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

SMG1_MOUSE
θ value	1.08474e-45 (rank : 7)	NC score	0.711289 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	212	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SMG1_HUMAN
θ value	1.41672e-45 (rank : 8)	NC score	0.705802 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

PRKDC_HUMAN
θ value	1.20211e-36 (rank : 9)	NC score	0.687440 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

PRKDC_MOUSE
θ value	4.27553e-34 (rank : 10)	NC score	0.690161 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

TRRAP_MOUSE
θ value	1.80466e-16 (rank : 11)	NC score	0.465262 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q80YV3, Q8C0Z5, Q8K104	Gene names	Trrap
Domain Architecture
Description	Transformation/transcription domain-associated protein (Tra1 homolog).

TRRAP_HUMAN
θ value	2.35696e-16 (rank : 12)	NC score	0.455913 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

PK3C3_MOUSE
θ value	2.52405e-10 (rank : 13)	NC score	0.464222 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

PK3C3_HUMAN
θ value	2.13673e-09 (rank : 14)	NC score	0.461092 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

PK3CG_MOUSE
θ value	3.41135e-07 (rank : 15)	NC score	0.366614 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_HUMAN
θ value	7.59969e-07 (rank : 16)	NC score	0.367331 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

P3C2A_MOUSE
θ value	6.43352e-06 (rank : 17)	NC score	0.288746 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	181	Shared Neighborhood Hits	28
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

P3C2A_HUMAN
θ value	8.40245e-06 (rank : 18)	NC score	0.286333 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	188	Shared Neighborhood Hits	28
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

PI4KB_HUMAN
θ value	3.19293e-05 (rank : 19)	NC score	0.376479 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

PI4KB_MOUSE
θ value	3.19293e-05 (rank : 20)	NC score	0.373304 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	67	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BKC8, Q8C146	Gene names	Pik4cb
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).

PK3CB_HUMAN
θ value	3.19293e-05 (rank : 21)	NC score	0.365528 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_MOUSE
θ value	3.19293e-05 (rank : 22)	NC score	0.365594 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CD_HUMAN
θ value	5.44631e-05 (rank : 23)	NC score	0.356409 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_MOUSE
θ value	5.44631e-05 (rank : 24)	NC score	0.357315 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

P3C2G_MOUSE
θ value	9.29e-05 (rank : 25)	NC score	0.326273 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	28
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

P3C2G_HUMAN
θ value	0.00020696 (rank : 26)	NC score	0.318408 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	29
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PI4KA_HUMAN
θ value	0.000461057 (rank : 27)	NC score	0.333225 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

PK3CA_HUMAN
θ value	0.00175202 (rank : 28)	NC score	0.320491 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_MOUSE
θ value	0.00175202 (rank : 29)	NC score	0.320237 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

P3C2B_HUMAN
θ value	0.0193708 (rank : 30)	NC score	0.255631 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	148	Shared Neighborhood Hits	28
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

NR5A2_MOUSE
θ value	0.0563607 (rank : 31)	NC score	0.032179 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

NR5A2_HUMAN
θ value	0.163984 (rank : 32)	NC score	0.020258 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

CAND1_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.060575 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CAND1_MOUSE
θ value	0.47712 (rank : 34)	NC score	0.056387 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

SYCP1_MOUSE
θ value	0.47712 (rank : 35)	NC score	0.007090 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	1456	Shared Neighborhood Hits	9
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CF152_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.027806 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	597	Shared Neighborhood Hits	9
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

TF3C3_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.029248 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

UTP20_MOUSE
θ value	1.38821 (rank : 38)	NC score	0.024827 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XG71, Q80V22, Q8BXH9, Q8CHL6, Q99K11	Gene names	Utp20, Drim
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein).

ABCC8_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.011171 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

TTBK2_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.007341 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	822	Shared Neighborhood Hits	3
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

KIFA3_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.031834 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).

SMC2_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.013718 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	1405	Shared Neighborhood Hits	14
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SKIL_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.010830 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	460	Shared Neighborhood Hits	9
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

UBD_MOUSE
θ value	4.03905 (rank : 44)	NC score	0.035667 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P63072, Q9WV10	Gene names	Ubd, Fat10
Domain Architecture	No domain graphic available
Description	Ubiquitin D (Ubiquitin-like protein FAT10) (Diubiquitin).

CADH7_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.001299 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULB5, Q9H157	Gene names	CDH7, CDH7L1
Domain Architecture
Description	Cadherin-7 precursor.

HM2L1_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.014880 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	130	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

SMC2_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.015090 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	1131	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

CB010_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.014994 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

CHD6_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.005426 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.005398 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

KIFA3_MOUSE
θ value	6.88961 (rank : 51)	NC score	0.019263 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P70188, P70189	Gene names	Kifap3
Domain Architecture
Description	Kinesin-associated protein 3 (KAP3).

PDE6C_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.006790 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P51160, Q5VY29	Gene names	PDE6C, PDEA2
Domain Architecture
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

SETBP_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.009261 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	305	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

TBL3_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.011073 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q12788	Gene names	TBL3, SAZD
Domain Architecture
Description	WD repeat protein SAZD (Transducin beta-like 3 protein).

TCRG1_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.016407 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	929	Shared Neighborhood Hits	13
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.012574 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	947	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

UBE1L_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.008645 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

BMR1B_HUMAN
θ value	8.99809 (rank : 58)	NC score	-0.000600 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	760	Shared Neighborhood Hits	3
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

BMR1B_MOUSE
θ value	8.99809 (rank : 59)	NC score	-0.000628 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	758	Shared Neighborhood Hits	3
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

CF152_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.015701 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	704	Shared Neighborhood Hits	8
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

CTNA2_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.007070 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3Y0	Gene names	CTNNA2, CAPR
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

CTNA2_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.007122 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q61301, Q61300, Q6AXD1	Gene names	Ctnna2, Catna2
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

UTP20_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.019551 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

Hits sorted by NC score

ATR_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	63	Target Neighborhood Hits	63	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

ATR_HUMAN
NC score	0.996814 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	63	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	Q13535, Q7KYL3, Q93051, Q9BXK4	Gene names	ATR, FRP1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).

ATM_MOUSE
NC score	0.812630 (rank : 3)	θ value	2.64101e-84 (rank : 4)
Query Neighborhood Hits	63	Target Neighborhood Hits	93	Shared Neighborhood Hits	32
SwissProt Accessions	Q62388	Gene names	Atm
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T, mutated homolog).

ATM_HUMAN
NC score	0.806565 (rank : 4)	θ value	1.18549e-84 (rank : 3)
Query Neighborhood Hits	63	Target Neighborhood Hits	78	Shared Neighborhood Hits	32
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

FRAP_MOUSE
NC score	0.762427 (rank : 5)	θ value	1.61718e-49 (rank : 5)
Query Neighborhood Hits	63	Target Neighborhood Hits	77	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
NC score	0.761111 (rank : 6)	θ value	8.02596e-49 (rank : 6)
Query Neighborhood Hits	63	Target Neighborhood Hits	83	Shared Neighborhood Hits	32
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

SMG1_MOUSE
NC score	0.711289 (rank : 7)	θ value	1.08474e-45 (rank : 7)
Query Neighborhood Hits	63	Target Neighborhood Hits	212	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SMG1_HUMAN
NC score	0.705802 (rank : 8)	θ value	1.41672e-45 (rank : 8)
Query Neighborhood Hits	63	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

PRKDC_MOUSE
NC score	0.690161 (rank : 9)	θ value	4.27553e-34 (rank : 10)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341	Gene names	Prkdc, Xrcc7
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).

PRKDC_HUMAN
NC score	0.687440 (rank : 10)	θ value	1.20211e-36 (rank : 9)
Query Neighborhood Hits	63	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3	Gene names	PRKDC
Domain Architecture
Description	DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).

TRRAP_MOUSE
NC score	0.465262 (rank : 11)	θ value	1.80466e-16 (rank : 11)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q80YV3, Q8C0Z5, Q8K104	Gene names	Trrap
Domain Architecture
Description	Transformation/transcription domain-associated protein (Tra1 homolog).

PK3C3_MOUSE
NC score	0.464222 (rank : 12)	θ value	2.52405e-10 (rank : 13)
Query Neighborhood Hits	63	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

PK3C3_HUMAN
NC score	0.461092 (rank : 13)	θ value	2.13673e-09 (rank : 14)
Query Neighborhood Hits	63	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

TRRAP_HUMAN
NC score	0.455913 (rank : 14)	θ value	2.35696e-16 (rank : 12)
Query Neighborhood Hits	63	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

PI4KB_HUMAN
NC score	0.376479 (rank : 15)	θ value	3.19293e-05 (rank : 19)
Query Neighborhood Hits	63	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBF8, O15096, P78405, Q9BWR6	Gene names	PIK4CB, PI4KB
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).

PI4KB_MOUSE
NC score	0.373304 (rank : 16)	θ value	3.19293e-05 (rank : 20)
Query Neighborhood Hits	63	Target Neighborhood Hits	67	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BKC8, Q8C146	Gene names	Pik4cb
Domain Architecture
Description	Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).

PK3CG_HUMAN
NC score	0.367331 (rank : 17)	θ value	7.59969e-07 (rank : 16)
Query Neighborhood Hits	63	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	P48736, Q8IV23, Q9BZC8	Gene names	PIK3CG
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CG_MOUSE
NC score	0.366614 (rank : 18)	θ value	3.41135e-07 (rank : 15)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JHG7	Gene names	Pik3cg, Pi3kg1
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).

PK3CB_MOUSE
NC score	0.365594 (rank : 19)	θ value	3.19293e-05 (rank : 22)
Query Neighborhood Hits	63	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI9	Gene names	Pik3cb
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CB_HUMAN
NC score	0.365528 (rank : 20)	θ value	3.19293e-05 (rank : 21)
Query Neighborhood Hits	63	Target Neighborhood Hits	43	Shared Neighborhood Hits	28
SwissProt Accessions	P42338	Gene names	PIK3CB
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).

PK3CD_MOUSE
NC score	0.357315 (rank : 21)	θ value	5.44631e-05 (rank : 24)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	O35904	Gene names	Pik3cd
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PK3CD_HUMAN
NC score	0.356409 (rank : 22)	θ value	5.44631e-05 (rank : 23)
Query Neighborhood Hits	63	Target Neighborhood Hits	40	Shared Neighborhood Hits	28
SwissProt Accessions	O00329, O15445	Gene names	PIK3CD
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).

PI4KA_HUMAN
NC score	0.333225 (rank : 23)	θ value	0.000461057 (rank : 27)
Query Neighborhood Hits	63	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

P3C2G_MOUSE
NC score	0.326273 (rank : 24)	θ value	9.29e-05 (rank : 25)
Query Neighborhood Hits	63	Target Neighborhood Hits	113	Shared Neighborhood Hits	28
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PK3CA_HUMAN
NC score	0.320491 (rank : 25)	θ value	0.00175202 (rank : 28)
Query Neighborhood Hits	63	Target Neighborhood Hits	45	Shared Neighborhood Hits	28
SwissProt Accessions	P42336, Q99762	Gene names	PIK3CA
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

PK3CA_MOUSE
NC score	0.320237 (rank : 26)	θ value	0.00175202 (rank : 29)
Query Neighborhood Hits	63	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	P42337	Gene names	Pik3ca
Domain Architecture
Description	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).

P3C2G_HUMAN
NC score	0.318408 (rank : 27)	θ value	0.00020696 (rank : 26)
Query Neighborhood Hits	63	Target Neighborhood Hits	92	Shared Neighborhood Hits	29
SwissProt Accessions	O75747	Gene names	PIK3C2G
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

P3C2A_MOUSE
NC score	0.288746 (rank : 28)	θ value	6.43352e-06 (rank : 17)
Query Neighborhood Hits	63	Target Neighborhood Hits	181	Shared Neighborhood Hits	28
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

P3C2A_HUMAN
NC score	0.286333 (rank : 29)	θ value	8.40245e-06 (rank : 18)
Query Neighborhood Hits	63	Target Neighborhood Hits	188	Shared Neighborhood Hits	28
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2B_HUMAN
NC score	0.255631 (rank : 30)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	63	Target Neighborhood Hits	148	Shared Neighborhood Hits	28
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

CAND1_HUMAN
NC score	0.060575 (rank : 31)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	63	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CAND1_MOUSE
NC score	0.056387 (rank : 32)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	63	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

UBD_MOUSE
NC score	0.035667 (rank : 33)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	63	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P63072, Q9WV10	Gene names	Ubd, Fat10
Domain Architecture	No domain graphic available
Description	Ubiquitin D (Ubiquitin-like protein FAT10) (Diubiquitin).

NR5A2_MOUSE
NC score	0.032179 (rank : 34)	θ value	0.0563607 (rank : 31)
Query Neighborhood Hits	63	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

KIFA3_HUMAN
NC score	0.031834 (rank : 35)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	63	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).

TF3C3_HUMAN
NC score	0.029248 (rank : 36)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	63	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

CF152_MOUSE
NC score	0.027806 (rank : 37)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	63	Target Neighborhood Hits	597	Shared Neighborhood Hits	9
SwissProt Accessions	Q80ST9, Q9CYM9, Q9D5J9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf152 homolog.

UTP20_MOUSE
NC score	0.024827 (rank : 38)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	63	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XG71, Q80V22, Q8BXH9, Q8CHL6, Q99K11	Gene names	Utp20, Drim
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein).

NR5A2_HUMAN
NC score	0.020258 (rank : 39)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	63	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

UTP20_HUMAN
NC score	0.019551 (rank : 40)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	63	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

KIFA3_MOUSE
NC score	0.019263 (rank : 41)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	63	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P70188, P70189	Gene names	Kifap3
Domain Architecture
Description	Kinesin-associated protein 3 (KAP3).

TCRG1_HUMAN
NC score	0.016407 (rank : 42)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	63	Target Neighborhood Hits	929	Shared Neighborhood Hits	13
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

CF152_HUMAN
NC score	0.015701 (rank : 43)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	63	Target Neighborhood Hits	704	Shared Neighborhood Hits	8
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

SMC2_MOUSE
NC score	0.015090 (rank : 44)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	63	Target Neighborhood Hits	1131	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

CB010_HUMAN
NC score	0.014994 (rank : 45)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	63	Target Neighborhood Hits	130	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

HM2L1_HUMAN
NC score	0.014880 (rank : 46)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	63	Target Neighborhood Hits	130	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

SMC2_HUMAN
NC score	0.013718 (rank : 47)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	63	Target Neighborhood Hits	1405	Shared Neighborhood Hits	14
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TCRG1_MOUSE
NC score	0.012574 (rank : 48)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	63	Target Neighborhood Hits	947	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

ABCC8_HUMAN
NC score	0.011171 (rank : 49)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	63	Target Neighborhood Hits	118	Shared Neighborhood Hits	4
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

TBL3_HUMAN
NC score	0.011073 (rank : 50)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	63	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q12788	Gene names	TBL3, SAZD
Domain Architecture
Description	WD repeat protein SAZD (Transducin beta-like 3 protein).

SKIL_HUMAN
NC score	0.010830 (rank : 51)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	63	Target Neighborhood Hits	460	Shared Neighborhood Hits	9
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SETBP_HUMAN
NC score	0.009261 (rank : 52)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	63	Target Neighborhood Hits	305	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

UBE1L_HUMAN
NC score	0.008645 (rank : 53)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	63	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P41226	Gene names	UBE1L, UBE2
Domain Architecture
Description	Ubiquitin-activating enzyme E1 homolog (D8).

TTBK2_HUMAN
NC score	0.007341 (rank : 54)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	63	Target Neighborhood Hits	822	Shared Neighborhood Hits	3
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

CTNA2_MOUSE
NC score	0.007122 (rank : 55)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	63	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q61301, Q61300, Q6AXD1	Gene names	Ctnna2, Catna2
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

SYCP1_MOUSE
NC score	0.007090 (rank : 56)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	63	Target Neighborhood Hits	1456	Shared Neighborhood Hits	9
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CTNA2_HUMAN
NC score	0.007070 (rank : 57)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	63	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3Y0	Gene names	CTNNA2, CAPR
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

PDE6C_HUMAN
NC score	0.006790 (rank : 58)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	63	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P51160, Q5VY29	Gene names	PDE6C, PDEA2
Domain Architecture
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

CHD6_HUMAN
NC score	0.005426 (rank : 59)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	63	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
NC score	0.005398 (rank : 60)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	63	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CADH7_HUMAN
NC score	0.001299 (rank : 61)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	63	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULB5, Q9H157	Gene names	CDH7, CDH7L1
Domain Architecture
Description	Cadherin-7 precursor.

BMR1B_HUMAN
NC score	-0.000600 (rank : 62)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	63	Target Neighborhood Hits	760	Shared Neighborhood Hits	3
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

BMR1B_MOUSE
NC score	-0.000628 (rank : 63)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	63	Target Neighborhood Hits	758	Shared Neighborhood Hits	3
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).