Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : ATR_HUMAN

For an explanation of this page, click here

ATR_HUMAN
 
SwissProt Accessions Q13535, Q7KYL3, Q93051, Q9BXK4 Gene names ATR, FRP1
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).
Rank Plots



Hits sorted by θ


ATR_HUMAN
 
θ value 0 (rank : 1) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 71 Target Neighborhood Hits 71 Shared Neighborhood Hits 71
SwissProt Accessions Q13535, Q7KYL3, Q93051, Q9BXK4 Gene names ATR, FRP1
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).
ATR_MOUSE
 
θ value 0 (rank : 2) NC score 0.996814 (rank : 2)
Query Neighborhood Hits 71 Target Neighborhood Hits 63 Shared Neighborhood Hits 45
SwissProt Accessions Q9JKK8 Gene names Atr
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).
ATM_MOUSE
 
θ value 2.23575e-83 (rank : 3) NC score 0.800833 (rank : 3)
Query Neighborhood Hits 71 Target Neighborhood Hits 93 Shared Neighborhood Hits 33
SwissProt Accessions Q62388 Gene names Atm
Domain
Architecture
Description Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T, mutated homolog).
ATM_HUMAN
 
θ value 1.7238e-59 (rank : 4) NC score 0.794003 (rank : 4)
Query Neighborhood Hits 71 Target Neighborhood Hits 78 Shared Neighborhood Hits 32
SwissProt Accessions Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7 Gene names ATM
Domain
Architecture
Description Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).
FRAP_MOUSE
 
θ value 3.84914e-51 (rank : 5) NC score 0.765309 (rank : 5)
Query Neighborhood Hits 71 Target Neighborhood Hits 77 Shared Neighborhood Hits 34
SwissProt Accessions Q9JLN9, Q811J5, Q9CST1 Gene names Frap1, Frap
Domain
Architecture
Description FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).
FRAP_HUMAN
 
θ value 1.91031e-50 (rank : 6) NC score 0.763938 (rank : 6)
Query Neighborhood Hits 71 Target Neighborhood Hits 83 Shared Neighborhood Hits 34
SwissProt Accessions P42345, Q6LE87, Q96QG3, Q9Y4I3 Gene names FRAP1, FRAP, FRAP2
Domain
Architecture
Description FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).
SMG1_MOUSE
 
θ value 4.40402e-47 (rank : 7) NC score 0.714042 (rank : 7)
Query Neighborhood Hits 71 Target Neighborhood Hits 212 Shared Neighborhood Hits 35
SwissProt Accessions Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3 Gene names Smg1, Kiaa0421
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).
SMG1_HUMAN
 
θ value 5.7518e-47 (rank : 8) NC score 0.708641 (rank : 8)
Query Neighborhood Hits 71 Target Neighborhood Hits 231 Shared Neighborhood Hits 35
SwissProt Accessions Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3 Gene names SMG1, ATX, KIAA0421, LIP
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).
PRKDC_HUMAN
 
θ value 9.83387e-39 (rank : 9) NC score 0.693285 (rank : 10)
Query Neighborhood Hits 71 Target Neighborhood Hits 93 Shared Neighborhood Hits 30
SwissProt Accessions P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3 Gene names PRKDC
Domain
Architecture
Description DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).
PRKDC_MOUSE
 
θ value 1.57e-36 (rank : 10) NC score 0.696522 (rank : 9)
Query Neighborhood Hits 71 Target Neighborhood Hits 92 Shared Neighborhood Hits 31
SwissProt Accessions P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341 Gene names Prkdc, Xrcc7
Domain
Architecture
Description DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).
TRRAP_MOUSE
 
θ value 8.65492e-19 (rank : 11) NC score 0.477974 (rank : 11)
Query Neighborhood Hits 71 Target Neighborhood Hits 42 Shared Neighborhood Hits 15
SwissProt Accessions Q80YV3, Q8C0Z5, Q8K104 Gene names Trrap
Domain
Architecture
Description Transformation/transcription domain-associated protein (Tra1 homolog).
TRRAP_HUMAN
 
θ value 1.13037e-18 (rank : 12) NC score 0.468437 (rank : 12)
Query Neighborhood Hits 71 Target Neighborhood Hits 117 Shared Neighborhood Hits 15
SwissProt Accessions Q9Y4A5, O75218, Q9Y631, Q9Y6H4 Gene names TRRAP, PAF400
Domain
Architecture
Description Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).
PK3C3_MOUSE
 
θ value 3.29651e-10 (rank : 13) NC score 0.464131 (rank : 13)
Query Neighborhood Hits 71 Target Neighborhood Hits 49 Shared Neighborhood Hits 30
SwissProt Accessions Q6PF93, Q8R3S8 Gene names Pik3c3
Domain
Architecture

No domain graphic available

Description Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).
PK3C3_HUMAN
 
θ value 1.25267e-09 (rank : 14) NC score 0.461052 (rank : 14)
Query Neighborhood Hits 71 Target Neighborhood Hits 49 Shared Neighborhood Hits 30
SwissProt Accessions Q8NEB9, Q15134 Gene names PIK3C3
Domain
Architecture

No domain graphic available

Description Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).
PK3CG_MOUSE
 
θ value 1.53129e-07 (rank : 15) NC score 0.368325 (rank : 18)
Query Neighborhood Hits 71 Target Neighborhood Hits 43 Shared Neighborhood Hits 28
SwissProt Accessions Q9JHG7 Gene names Pik3cg, Pi3kg1
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).
PK3CG_HUMAN
 
θ value 3.41135e-07 (rank : 16) NC score 0.369032 (rank : 17)
Query Neighborhood Hits 71 Target Neighborhood Hits 41 Shared Neighborhood Hits 28
SwissProt Accessions P48736, Q8IV23, Q9BZC8 Gene names PIK3CG
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).
PK3CB_HUMAN
 
θ value 1.09739e-05 (rank : 17) NC score 0.367675 (rank : 20)
Query Neighborhood Hits 71 Target Neighborhood Hits 43 Shared Neighborhood Hits 28
SwissProt Accessions P42338 Gene names PIK3CB
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).
PK3CB_MOUSE
 
θ value 1.09739e-05 (rank : 18) NC score 0.367773 (rank : 19)
Query Neighborhood Hits 71 Target Neighborhood Hits 49 Shared Neighborhood Hits 28
SwissProt Accessions Q8BTI9 Gene names Pik3cb
Domain
Architecture

No domain graphic available

Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).
P3C2A_HUMAN
 
θ value 1.87187e-05 (rank : 19) NC score 0.286253 (rank : 29)
Query Neighborhood Hits 71 Target Neighborhood Hits 188 Shared Neighborhood Hits 28
SwissProt Accessions O00443 Gene names PIK3C2A
Domain
Architecture

No domain graphic available

Description Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).
P3C2A_MOUSE
 
θ value 1.87187e-05 (rank : 20) NC score 0.288660 (rank : 28)
Query Neighborhood Hits 71 Target Neighborhood Hits 181 Shared Neighborhood Hits 28
SwissProt Accessions Q61194, Q61182 Gene names Pik3c2a, Cpk
Domain
Architecture

No domain graphic available

Description Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).
PI4KB_HUMAN
 
θ value 2.44474e-05 (rank : 21) NC score 0.376881 (rank : 15)
Query Neighborhood Hits 71 Target Neighborhood Hits 79 Shared Neighborhood Hits 28
SwissProt Accessions Q9UBF8, O15096, P78405, Q9BWR6 Gene names PIK4CB, PI4KB
Domain
Architecture
Description Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).
PK3CD_HUMAN
 
θ value 2.44474e-05 (rank : 22) NC score 0.358702 (rank : 22)
Query Neighborhood Hits 71 Target Neighborhood Hits 40 Shared Neighborhood Hits 28
SwissProt Accessions O00329, O15445 Gene names PIK3CD
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).
PK3CD_MOUSE
 
θ value 2.44474e-05 (rank : 23) NC score 0.359761 (rank : 21)
Query Neighborhood Hits 71 Target Neighborhood Hits 42 Shared Neighborhood Hits 30
SwissProt Accessions O35904 Gene names Pik3cd
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).
PI4KB_MOUSE
 
θ value 3.19293e-05 (rank : 24) NC score 0.373726 (rank : 16)
Query Neighborhood Hits 71 Target Neighborhood Hits 67 Shared Neighborhood Hits 28
SwissProt Accessions Q8BKC8, Q8C146 Gene names Pik4cb
Domain
Architecture
Description Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).
P3C2G_MOUSE
 
θ value 0.000270298 (rank : 25) NC score 0.324750 (rank : 24)
Query Neighborhood Hits 71 Target Neighborhood Hits 113 Shared Neighborhood Hits 28
SwissProt Accessions O70167, O70168 Gene names Pik3c2g
Domain
Architecture
Description Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).
PI4KA_HUMAN
 
θ value 0.000461057 (rank : 26) NC score 0.333679 (rank : 23)
Query Neighborhood Hits 71 Target Neighborhood Hits 53 Shared Neighborhood Hits 28
SwissProt Accessions P42356, Q7Z625, Q9UPG2 Gene names PIK4CA, PIK4
Domain
Architecture
Description Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).
P3C2G_HUMAN
 
θ value 0.000602161 (rank : 27) NC score 0.316835 (rank : 27)
Query Neighborhood Hits 71 Target Neighborhood Hits 92 Shared Neighborhood Hits 28
SwissProt Accessions O75747 Gene names PIK3C2G
Domain
Architecture
Description Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).
PK3CA_HUMAN
 
θ value 0.00175202 (rank : 28) NC score 0.321949 (rank : 25)
Query Neighborhood Hits 71 Target Neighborhood Hits 45 Shared Neighborhood Hits 28
SwissProt Accessions P42336, Q99762 Gene names PIK3CA
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).
PK3CA_MOUSE
 
θ value 0.00175202 (rank : 29) NC score 0.321687 (rank : 26)
Query Neighborhood Hits 71 Target Neighborhood Hits 48 Shared Neighborhood Hits 28
SwissProt Accessions P42337 Gene names Pik3ca
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).
P3C2B_HUMAN
 
θ value 0.0252991 (rank : 30) NC score 0.255712 (rank : 30)
Query Neighborhood Hits 71 Target Neighborhood Hits 148 Shared Neighborhood Hits 28
SwissProt Accessions O00750, O95666, Q5SW99 Gene names PIK3C2B
Domain
Architecture
Description Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).
NR5A2_MOUSE
 
θ value 0.0736092 (rank : 31) NC score 0.025852 (rank : 39)
Query Neighborhood Hits 71 Target Neighborhood Hits 107 Shared Neighborhood Hits 3
SwissProt Accessions P45448 Gene names Nr5a2, Lrh1
Domain
Architecture
Description Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).
CAND1_HUMAN
 
θ value 0.0961366 (rank : 32) NC score 0.064651 (rank : 31)
Query Neighborhood Hits 71 Target Neighborhood Hits 45 Shared Neighborhood Hits 7
SwissProt Accessions Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85 Gene names CAND1, KIAA0829, TIP120, TIP120A
Domain
Architecture

No domain graphic available

Description Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).
CAND1_MOUSE
 
θ value 0.21417 (rank : 33) NC score 0.060458 (rank : 32)
Query Neighborhood Hits 71 Target Neighborhood Hits 42 Shared Neighborhood Hits 7
SwissProt Accessions Q6ZQ38, Q6PFR0, Q9CV45 Gene names Cand1, D10Ertd516e, Kiaa0829
Domain
Architecture

No domain graphic available

Description Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).
SYYC_HUMAN
 
θ value 0.62314 (rank : 34) NC score 0.037522 (rank : 34)
Query Neighborhood Hits 71 Target Neighborhood Hits 18 Shared Neighborhood Hits 3
SwissProt Accessions P54577, O43276, Q53EN1 Gene names YARS
Domain
Architecture
Description Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).
CF152_MOUSE
 
θ value 1.06291 (rank : 35) NC score 0.029634 (rank : 37)
Query Neighborhood Hits 71 Target Neighborhood Hits 597 Shared Neighborhood Hits 10
SwissProt Accessions Q80ST9, Q9CYM9, Q9D5J9 Gene names
Domain
Architecture

No domain graphic available

Description Protein C6orf152 homolog.
MDN1_HUMAN
 
θ value 1.38821 (rank : 36) NC score 0.019373 (rank : 41)
Query Neighborhood Hits 71 Target Neighborhood Hits 662 Shared Neighborhood Hits 7
SwissProt Accessions Q9NU22, O15019 Gene names MDN1, KIAA0301
Domain
Architecture
Description Midasin (MIDAS-containing protein).
SYYC_MOUSE
 
θ value 1.38821 (rank : 37) NC score 0.034088 (rank : 36)
Query Neighborhood Hits 71 Target Neighborhood Hits 27 Shared Neighborhood Hits 3
SwissProt Accessions Q91WQ3, Q3TEC8, Q3U9A1, Q3UTA7, Q8BVT2, Q8C183 Gene names Yars
Domain
Architecture

No domain graphic available

Description Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).
TBL3_HUMAN
 
θ value 1.38821 (rank : 38) NC score 0.013778 (rank : 51)
Query Neighborhood Hits 71 Target Neighborhood Hits 286 Shared Neighborhood Hits 3
SwissProt Accessions Q12788 Gene names TBL3, SAZD
Domain
Architecture
Description WD repeat protein SAZD (Transducin beta-like 3 protein).
ABCC8_HUMAN
 
θ value 1.81305 (rank : 39) NC score 0.011167 (rank : 56)
Query Neighborhood Hits 71 Target Neighborhood Hits 118 Shared Neighborhood Hits 4
SwissProt Accessions Q09428, O75948, Q16583 Gene names ABCC8, SUR, SUR1
Domain
Architecture
Description ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).
CF152_HUMAN
 
θ value 2.36792 (rank : 40) NC score 0.017758 (rank : 43)
Query Neighborhood Hits 71 Target Neighborhood Hits 704 Shared Neighborhood Hits 10
SwissProt Accessions Q86VQ0, Q9BWX7 Gene names C6orf152
Domain
Architecture

No domain graphic available

Description Protein C6orf152.
CTND1_HUMAN
 
θ value 3.0926 (rank : 41) NC score 0.011437 (rank : 55)
Query Neighborhood Hits 71 Target Neighborhood Hits 67 Shared Neighborhood Hits 3
SwissProt Accessions O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73 Gene names CTNND1, KIAA0384
Domain
Architecture
Description Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).
MK12_HUMAN
 
θ value 3.0926 (rank : 42) NC score -0.000285 (rank : 69)
Query Neighborhood Hits 71 Target Neighborhood Hits 830 Shared Neighborhood Hits 7
SwissProt Accessions P53778, Q14260, Q99588, Q99672 Gene names MAPK12, ERK6, SAPK3
Domain
Architecture
Description Mitogen-activated protein kinase 12 (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma).
SYNE1_HUMAN
 
θ value 3.0926 (rank : 43) NC score 0.009957 (rank : 57)
Query Neighborhood Hits 71 Target Neighborhood Hits 1484 Shared Neighborhood Hits 15
SwissProt Accessions Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8 Gene names SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain
Architecture
Description Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).
TTBK2_HUMAN
 
θ value 3.0926 (rank : 44) NC score 0.009157 (rank : 59)
Query Neighborhood Hits 71 Target Neighborhood Hits 822 Shared Neighborhood Hits 8
SwissProt Accessions Q6IQ55, O94932, Q6ZN52, Q8IVV1 Gene names TTBK2, KIAA0847
Domain
Architecture

No domain graphic available

Description Tau-tubulin kinase 2 (EC 2.7.11.1).
ALS2_MOUSE
 
θ value 4.03905 (rank : 45) NC score 0.015016 (rank : 49)
Query Neighborhood Hits 71 Target Neighborhood Hits 111 Shared Neighborhood Hits 4
SwissProt Accessions Q920R0, Q8JZR1, Q9CXJ3 Gene names Als2
Domain
Architecture
Description Alsin (Amyotrophic lateral sclerosis protein 2 homolog).
CCD46_HUMAN
 
θ value 4.03905 (rank : 46) NC score 0.008135 (rank : 62)
Query Neighborhood Hits 71 Target Neighborhood Hits 1430 Shared Neighborhood Hits 16
SwissProt Accessions Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4 Gene names CCDC46
Domain
Architecture

No domain graphic available

Description Coiled-coil domain-containing protein 46.
INSC_HUMAN
 
θ value 4.03905 (rank : 47) NC score 0.016766 (rank : 45)
Query Neighborhood Hits 71 Target Neighborhood Hits 17 Shared Neighborhood Hits 2
SwissProt Accessions Q1MX18, Q1MX19, Q3C1V6, Q4AC95, Q4AC96, Q4AC97, Q4AC98 Gene names INSC
Domain
Architecture

No domain graphic available

Description Protein inscuteable homolog.
KIFA3_HUMAN
 
θ value 4.03905 (rank : 48) NC score 0.025892 (rank : 38)
Query Neighborhood Hits 71 Target Neighborhood Hits 29 Shared Neighborhood Hits 3
SwissProt Accessions Q92845, Q8NHU7, Q9H416 Gene names KIFAP3, SMAP
Domain
Architecture
Description Kinesin-associated protein 3 (Smg GDS-associated protein).
PSMD2_HUMAN
 
θ value 4.03905 (rank : 49) NC score 0.019478 (rank : 40)
Query Neighborhood Hits 71 Target Neighborhood Hits 88 Shared Neighborhood Hits 4
SwissProt Accessions Q13200, Q12932, Q15321, Q96I12 Gene names PSMD2, TRAP2
Domain
Architecture

No domain graphic available

Description 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Tumor necrosis factor type 1 receptor- associated protein 2) (55.11 protein).
TCF25_HUMAN
 
θ value 4.03905 (rank : 50) NC score 0.016201 (rank : 46)
Query Neighborhood Hits 71 Target Neighborhood Hits 19 Shared Neighborhood Hits 2
SwissProt Accessions Q9BQ70, Q2MK75, Q9UPV3 Gene names TCF25, KIAA1049, NULP1
Domain
Architecture
Description Transcription factor 25 (Nuclear localized protein 1).
TCRG1_HUMAN
 
θ value 4.03905 (rank : 51) NC score 0.019159 (rank : 42)
Query Neighborhood Hits 71 Target Neighborhood Hits 929 Shared Neighborhood Hits 14
SwissProt Accessions O14776 Gene names TCERG1, CA150, TAF2S
Domain
Architecture

No domain graphic available

Description Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).
TCRG1_MOUSE
 
θ value 4.03905 (rank : 52) NC score 0.015233 (rank : 48)
Query Neighborhood Hits 71 Target Neighborhood Hits 947 Shared Neighborhood Hits 11
SwissProt Accessions Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5 Gene names Tcerg1, Taf2s
Domain
Architecture

No domain graphic available

Description Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).
UBD_MOUSE
 
θ value 4.03905 (rank : 53) NC score 0.035689 (rank : 35)
Query Neighborhood Hits 71 Target Neighborhood Hits 30 Shared Neighborhood Hits 3
SwissProt Accessions P63072, Q9WV10 Gene names Ubd, Fat10
Domain
Architecture

No domain graphic available

Description Ubiquitin D (Ubiquitin-like protein FAT10) (Diubiquitin).
ULK4_MOUSE
 
θ value 4.03905 (rank : 54) NC score 0.000722 (rank : 68)
Query Neighborhood Hits 71 Target Neighborhood Hits 793 Shared Neighborhood Hits 8
SwissProt Accessions Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6 Gene names Ulk4
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).
ALS2_HUMAN
 
θ value 5.27518 (rank : 55) NC score 0.013993 (rank : 50)
Query Neighborhood Hits 71 Target Neighborhood Hits 121 Shared Neighborhood Hits 4
SwissProt Accessions Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9 Gene names ALS2, KIAA1563
Domain
Architecture
Description Alsin (Amyotrophic lateral sclerosis protein 2).
CP250_MOUSE
 
θ value 5.27518 (rank : 56) NC score 0.005526 (rank : 65)
Query Neighborhood Hits 71 Target Neighborhood Hits 1583 Shared Neighborhood Hits 15
SwissProt Accessions Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6 Gene names Cep250, Cep2, Inmp
Domain
Architecture

No domain graphic available

Description Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).
ICAM1_MOUSE
 
θ value 5.27518 (rank : 57) NC score 0.009522 (rank : 58)
Query Neighborhood Hits 71 Target Neighborhood Hits 99 Shared Neighborhood Hits 2
SwissProt Accessions P13597, Q61828 Gene names Icam1, Icam-1
Domain
Architecture
Description Intercellular adhesion molecule 1 precursor (ICAM-1) (MALA-2).
PARVG_HUMAN
 
θ value 5.27518 (rank : 58) NC score 0.015465 (rank : 47)
Query Neighborhood Hits 71 Target Neighborhood Hits 44 Shared Neighborhood Hits 3
SwissProt Accessions Q9HBI0, Q9BQX5, Q9NSG1 Gene names PARVG
Domain
Architecture
Description Gamma-parvin.
STK36_HUMAN
 
θ value 5.27518 (rank : 59) NC score -0.001099 (rank : 70)
Query Neighborhood Hits 71 Target Neighborhood Hits 896 Shared Neighborhood Hits 8
SwissProt Accessions Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2 Gene names STK36, KIAA1278
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).
GATB_HUMAN
 
θ value 6.88961 (rank : 60) NC score 0.012325 (rank : 54)
Query Neighborhood Hits 71 Target Neighborhood Hits 8 Shared Neighborhood Hits 2
SwissProt Accessions O75879, Q9P0S6, Q9Y2B8 Gene names PET112L, PET112
Domain
Architecture
Description Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial precursor (EC 6.3.5.-) (Glu-ADT subunit B) (Cytochrome oxidase assembly factor PET112 homolog).
PDE6C_HUMAN
 
θ value 6.88961 (rank : 61) NC score 0.006777 (rank : 63)
Query Neighborhood Hits 71 Target Neighborhood Hits 56 Shared Neighborhood Hits 3
SwissProt Accessions P51160, Q5VY29 Gene names PDE6C, PDEA2
Domain
Architecture
Description Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).
PSMD2_MOUSE
 
θ value 6.88961 (rank : 62) NC score 0.017455 (rank : 44)
Query Neighborhood Hits 71 Target Neighborhood Hits 147 Shared Neighborhood Hits 6
SwissProt Accessions Q8VDM4 Gene names Psmd2
Domain
Architecture

No domain graphic available

Description 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).
SMC2_HUMAN
 
θ value 6.88961 (rank : 63) NC score 0.012542 (rank : 53)
Query Neighborhood Hits 71 Target Neighborhood Hits 1405 Shared Neighborhood Hits 18
SwissProt Accessions O95347, Q9P1P2 Gene names SMC2L1, CAPE, SMC2
Domain
Architecture
Description Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).
ANR32_MOUSE
 
θ value 8.99809 (rank : 64) NC score 0.003182 (rank : 67)
Query Neighborhood Hits 71 Target Neighborhood Hits 285 Shared Neighborhood Hits 2
SwissProt Accessions Q8R3P9, Q5XK30, Q8BHY5, Q921Y9 Gene names Ankrd32
Domain
Architecture

No domain graphic available

Description Ankyrin repeat domain-containing protein 32.
CTND1_MOUSE
 
θ value 8.99809 (rank : 65) NC score 0.008830 (rank : 60)
Query Neighborhood Hits 71 Target Neighborhood Hits 69 Shared Neighborhood Hits 3
SwissProt Accessions P30999 Gene names Ctnnd1, Catns
Domain
Architecture
Description Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).
GCN1L_HUMAN
 
θ value 8.99809 (rank : 66) NC score 0.037719 (rank : 33)
Query Neighborhood Hits 71 Target Neighborhood Hits 112 Shared Neighborhood Hits 9
SwissProt Accessions Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60 Gene names GCN1L1, KIAA0219
Domain
Architecture

No domain graphic available

Description GCN1-like protein 1 (HsGCN1).
GOGA4_MOUSE
 
θ value 8.99809 (rank : 67) NC score 0.008136 (rank : 61)
Query Neighborhood Hits 71 Target Neighborhood Hits 1939 Shared Neighborhood Hits 17
SwissProt Accessions Q91VW5, O70365, Q8CGH6 Gene names Golga4
Domain
Architecture
Description Golgin subfamily A member 4 (tGolgin-1).
NEK1_MOUSE
 
θ value 8.99809 (rank : 68) NC score -0.001659 (rank : 71)
Query Neighborhood Hits 71 Target Neighborhood Hits 1311 Shared Neighborhood Hits 13
SwissProt Accessions P51954 Gene names Nek1
Domain
Architecture
Description Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).
SMC2_MOUSE
 
θ value 8.99809 (rank : 69) NC score 0.013215 (rank : 52)
Query Neighborhood Hits 71 Target Neighborhood Hits 1131 Shared Neighborhood Hits 14
SwissProt Accessions Q8CG48, Q61076, Q9CS17, Q9CSD8 Gene names Smc2l1, Cape, Fin16, Smc2
Domain
Architecture
Description Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).
SORT_MOUSE
 
θ value 8.99809 (rank : 70) NC score 0.006091 (rank : 64)
Query Neighborhood Hits 71 Target Neighborhood Hits 13 Shared Neighborhood Hits 2
SwissProt Accessions Q6PHU5, Q3UHE2, Q8K043, Q9QXW6 Gene names Sort1
Domain
Architecture

No domain graphic available

Description Sortilin precursor (Neurotensin receptor 3) (NTR3) (mNTR3).
TTBK2_MOUSE
 
θ value 8.99809 (rank : 71) NC score 0.003375 (rank : 66)
Query Neighborhood Hits 71 Target Neighborhood Hits 811 Shared Neighborhood Hits 7
SwissProt Accessions Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8 Gene names Ttbk2, Kiaa0847, Ttbk1
Domain
Architecture

No domain graphic available

Description Tau-tubulin kinase 2.

Hits sorted by NC score


ATR_HUMAN
 
NC score 0.999962 (rank : 1) θ value 0 (rank : 1)
Query Neighborhood Hits 71 Target Neighborhood Hits 71 Shared Neighborhood Hits 71
SwissProt Accessions Q13535, Q7KYL3, Q93051, Q9BXK4 Gene names ATR, FRP1
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).
ATR_MOUSE
 
NC score 0.996814 (rank : 2) θ value 0 (rank : 2)
Query Neighborhood Hits 71 Target Neighborhood Hits 63 Shared Neighborhood Hits 45
SwissProt Accessions Q9JKK8 Gene names Atr
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).
ATM_MOUSE
 
NC score 0.800833 (rank : 3) θ value 2.23575e-83 (rank : 3)
Query Neighborhood Hits 71 Target Neighborhood Hits 93 Shared Neighborhood Hits 33
SwissProt Accessions Q62388 Gene names Atm
Domain
Architecture
Description Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated homolog) (A-T, mutated homolog).
ATM_HUMAN
 
NC score 0.794003 (rank : 4) θ value 1.7238e-59 (rank : 4)
Query Neighborhood Hits 71 Target Neighborhood Hits 78 Shared Neighborhood Hits 32
SwissProt Accessions Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7 Gene names ATM
Domain
Architecture
Description Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).
FRAP_MOUSE
 
NC score 0.765309 (rank : 5) θ value 3.84914e-51 (rank : 5)
Query Neighborhood Hits 71 Target Neighborhood Hits 77 Shared Neighborhood Hits 34
SwissProt Accessions Q9JLN9, Q811J5, Q9CST1 Gene names Frap1, Frap
Domain
Architecture
Description FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).
FRAP_HUMAN
 
NC score 0.763938 (rank : 6) θ value 1.91031e-50 (rank : 6)
Query Neighborhood Hits 71 Target Neighborhood Hits 83 Shared Neighborhood Hits 34
SwissProt Accessions P42345, Q6LE87, Q96QG3, Q9Y4I3 Gene names FRAP1, FRAP, FRAP2
Domain
Architecture
Description FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).
SMG1_MOUSE
 
NC score 0.714042 (rank : 7) θ value 4.40402e-47 (rank : 7)
Query Neighborhood Hits 71 Target Neighborhood Hits 212 Shared Neighborhood Hits 35
SwissProt Accessions Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3 Gene names Smg1, Kiaa0421
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).
SMG1_HUMAN
 
NC score 0.708641 (rank : 8) θ value 5.7518e-47 (rank : 8)
Query Neighborhood Hits 71 Target Neighborhood Hits 231 Shared Neighborhood Hits 35
SwissProt Accessions Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3 Gene names SMG1, ATX, KIAA0421, LIP
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).
PRKDC_MOUSE
 
NC score 0.696522 (rank : 9) θ value 1.57e-36 (rank : 10)
Query Neighborhood Hits 71 Target Neighborhood Hits 92 Shared Neighborhood Hits 31
SwissProt Accessions P97313, O88187, P97928, Q307W9, Q3V2W8, Q8C2A7, Q9Z341 Gene names Prkdc, Xrcc7
Domain
Architecture
Description DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (P460).
PRKDC_HUMAN
 
NC score 0.693285 (rank : 10) θ value 9.83387e-39 (rank : 9)
Query Neighborhood Hits 71 Target Neighborhood Hits 93 Shared Neighborhood Hits 30
SwissProt Accessions P78527, P78528, Q13327, Q13337, Q14175, Q59H99, Q7Z611, Q96SE6, Q9UME3 Gene names PRKDC
Domain
Architecture
Description DNA-dependent protein kinase catalytic subunit (EC 2.7.11.1) (DNA-PK catalytic subunit) (DNA-PKcs) (DNPK1) (p460).
TRRAP_MOUSE
 
NC score 0.477974 (rank : 11) θ value 8.65492e-19 (rank : 11)
Query Neighborhood Hits 71 Target Neighborhood Hits 42 Shared Neighborhood Hits 15
SwissProt Accessions Q80YV3, Q8C0Z5, Q8K104 Gene names Trrap
Domain
Architecture
Description Transformation/transcription domain-associated protein (Tra1 homolog).
TRRAP_HUMAN
 
NC score 0.468437 (rank : 12) θ value 1.13037e-18 (rank : 12)
Query Neighborhood Hits 71 Target Neighborhood Hits 117 Shared Neighborhood Hits 15
SwissProt Accessions Q9Y4A5, O75218, Q9Y631, Q9Y6H4 Gene names TRRAP, PAF400
Domain
Architecture
Description Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).
PK3C3_MOUSE
 
NC score 0.464131 (rank : 13) θ value 3.29651e-10 (rank : 13)
Query Neighborhood Hits 71 Target Neighborhood Hits 49 Shared Neighborhood Hits 30
SwissProt Accessions Q6PF93, Q8R3S8 Gene names Pik3c3
Domain
Architecture

No domain graphic available

Description Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).
PK3C3_HUMAN
 
NC score 0.461052 (rank : 14) θ value 1.25267e-09 (rank : 14)
Query Neighborhood Hits 71 Target Neighborhood Hits 49 Shared Neighborhood Hits 30
SwissProt Accessions Q8NEB9, Q15134 Gene names PIK3C3
Domain
Architecture

No domain graphic available

Description Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).
PI4KB_HUMAN
 
NC score 0.376881 (rank : 15) θ value 2.44474e-05 (rank : 21)
Query Neighborhood Hits 71 Target Neighborhood Hits 79 Shared Neighborhood Hits 28
SwissProt Accessions Q9UBF8, O15096, P78405, Q9BWR6 Gene names PIK4CB, PI4KB
Domain
Architecture
Description Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta) (NPIK) (PI4K92).
PI4KB_MOUSE
 
NC score 0.373726 (rank : 16) θ value 3.19293e-05 (rank : 24)
Query Neighborhood Hits 71 Target Neighborhood Hits 67 Shared Neighborhood Hits 28
SwissProt Accessions Q8BKC8, Q8C146 Gene names Pik4cb
Domain
Architecture
Description Phosphatidylinositol 4-kinase beta (EC 2.7.1.67) (PtdIns 4-kinase beta) (PI4Kbeta) (PI4K-beta).
PK3CG_HUMAN
 
NC score 0.369032 (rank : 17) θ value 3.41135e-07 (rank : 16)
Query Neighborhood Hits 71 Target Neighborhood Hits 41 Shared Neighborhood Hits 28
SwissProt Accessions P48736, Q8IV23, Q9BZC8 Gene names PIK3CG
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).
PK3CG_MOUSE
 
NC score 0.368325 (rank : 18) θ value 1.53129e-07 (rank : 15)
Query Neighborhood Hits 71 Target Neighborhood Hits 43 Shared Neighborhood Hits 28
SwissProt Accessions Q9JHG7 Gene names Pik3cg, Pi3kg1
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (EC 2.7.1.153) (PI3-kinase p110 subunit gamma) (PtdIns-3- kinase subunit p110) (PI3K) (PI3Kgamma) (p120-PI3K).
PK3CB_MOUSE
 
NC score 0.367773 (rank : 19) θ value 1.09739e-05 (rank : 18)
Query Neighborhood Hits 71 Target Neighborhood Hits 49 Shared Neighborhood Hits 28
SwissProt Accessions Q8BTI9 Gene names Pik3cb
Domain
Architecture

No domain graphic available

Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).
PK3CB_HUMAN
 
NC score 0.367675 (rank : 20) θ value 1.09739e-05 (rank : 17)
Query Neighborhood Hits 71 Target Neighborhood Hits 43 Shared Neighborhood Hits 28
SwissProt Accessions P42338 Gene names PIK3CB
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta).
PK3CD_MOUSE
 
NC score 0.359761 (rank : 21) θ value 2.44474e-05 (rank : 23)
Query Neighborhood Hits 71 Target Neighborhood Hits 42 Shared Neighborhood Hits 30
SwissProt Accessions O35904 Gene names Pik3cd
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).
PK3CD_HUMAN
 
NC score 0.358702 (rank : 22) θ value 2.44474e-05 (rank : 22)
Query Neighborhood Hits 71 Target Neighborhood Hits 40 Shared Neighborhood Hits 28
SwissProt Accessions O00329, O15445 Gene names PIK3CD
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform (EC 2.7.1.153) (PI3-kinase p110 subunit delta) (PtdIns-3- kinase p110) (PI3K) (p110delta).
PI4KA_HUMAN
 
NC score 0.333679 (rank : 23) θ value 0.000461057 (rank : 26)
Query Neighborhood Hits 71 Target Neighborhood Hits 53 Shared Neighborhood Hits 28
SwissProt Accessions P42356, Q7Z625, Q9UPG2 Gene names PIK4CA, PIK4
Domain
Architecture
Description Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).
P3C2G_MOUSE
 
NC score 0.324750 (rank : 24) θ value 0.000270298 (rank : 25)
Query Neighborhood Hits 71 Target Neighborhood Hits 113 Shared Neighborhood Hits 28
SwissProt Accessions O70167, O70168 Gene names Pik3c2g
Domain
Architecture
Description Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).
PK3CA_HUMAN
 
NC score 0.321949 (rank : 25) θ value 0.00175202 (rank : 28)
Query Neighborhood Hits 71 Target Neighborhood Hits 45 Shared Neighborhood Hits 28
SwissProt Accessions P42336, Q99762 Gene names PIK3CA
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).
PK3CA_MOUSE
 
NC score 0.321687 (rank : 26) θ value 0.00175202 (rank : 29)
Query Neighborhood Hits 71 Target Neighborhood Hits 48 Shared Neighborhood Hits 28
SwissProt Accessions P42337 Gene names Pik3ca
Domain
Architecture
Description Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) (PI3-kinase p110 subunit alpha) (PtdIns-3- kinase p110) (PI3K).
P3C2G_HUMAN
 
NC score 0.316835 (rank : 27) θ value 0.000602161 (rank : 27)
Query Neighborhood Hits 71 Target Neighborhood Hits 92 Shared Neighborhood Hits 28
SwissProt Accessions O75747 Gene names PIK3C2G
Domain
Architecture
Description Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).
P3C2A_MOUSE
 
NC score 0.288660 (rank : 28) θ value 1.87187e-05 (rank : 20)
Query Neighborhood Hits 71 Target Neighborhood Hits 181 Shared Neighborhood Hits 28
SwissProt Accessions Q61194, Q61182 Gene names Pik3c2a, Cpk
Domain
Architecture

No domain graphic available

Description Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).
P3C2A_HUMAN
 
NC score 0.286253 (rank : 29) θ value 1.87187e-05 (rank : 19)
Query Neighborhood Hits 71 Target Neighborhood Hits 188 Shared Neighborhood Hits 28
SwissProt Accessions O00443 Gene names PIK3C2A
Domain
Architecture

No domain graphic available

Description Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).
P3C2B_HUMAN
 
NC score 0.255712 (rank : 30) θ value 0.0252991 (rank : 30)
Query Neighborhood Hits 71 Target Neighborhood Hits 148 Shared Neighborhood Hits 28
SwissProt Accessions O00750, O95666, Q5SW99 Gene names PIK3C2B
Domain
Architecture
Description Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).
CAND1_HUMAN
 
NC score 0.064651 (rank : 31) θ value 0.0961366 (rank : 32)
Query Neighborhood Hits 71 Target Neighborhood Hits 45 Shared Neighborhood Hits 7
SwissProt Accessions Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85 Gene names CAND1, KIAA0829, TIP120, TIP120A
Domain
Architecture

No domain graphic available

Description Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).
CAND1_MOUSE
 
NC score 0.060458 (rank : 32) θ value 0.21417 (rank : 33)
Query Neighborhood Hits 71 Target Neighborhood Hits 42 Shared Neighborhood Hits 7
SwissProt Accessions Q6ZQ38, Q6PFR0, Q9CV45 Gene names Cand1, D10Ertd516e, Kiaa0829
Domain
Architecture

No domain graphic available

Description Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).
GCN1L_HUMAN
 
NC score 0.037719 (rank : 33) θ value 8.99809 (rank : 66)
Query Neighborhood Hits 71 Target Neighborhood Hits 112 Shared Neighborhood Hits 9
SwissProt Accessions Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60 Gene names GCN1L1, KIAA0219
Domain
Architecture

No domain graphic available

Description GCN1-like protein 1 (HsGCN1).
SYYC_HUMAN
 
NC score 0.037522 (rank : 34) θ value 0.62314 (rank : 34)
Query Neighborhood Hits 71 Target Neighborhood Hits 18 Shared Neighborhood Hits 3
SwissProt Accessions P54577, O43276, Q53EN1 Gene names YARS
Domain
Architecture
Description Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).
UBD_MOUSE
 
NC score 0.035689 (rank : 35) θ value 4.03905 (rank : 53)
Query Neighborhood Hits 71 Target Neighborhood Hits 30 Shared Neighborhood Hits 3
SwissProt Accessions P63072, Q9WV10 Gene names Ubd, Fat10
Domain
Architecture

No domain graphic available

Description Ubiquitin D (Ubiquitin-like protein FAT10) (Diubiquitin).
SYYC_MOUSE
 
NC score 0.034088 (rank : 36) θ value 1.38821 (rank : 37)
Query Neighborhood Hits 71 Target Neighborhood Hits 27 Shared Neighborhood Hits 3
SwissProt Accessions Q91WQ3, Q3TEC8, Q3U9A1, Q3UTA7, Q8BVT2, Q8C183 Gene names Yars
Domain
Architecture

No domain graphic available

Description Tyrosyl-tRNA synthetase, cytoplasmic (EC 6.1.1.1) (Tyrosyl--tRNA ligase) (TyrRS).
CF152_MOUSE
 
NC score 0.029634 (rank : 37) θ value 1.06291 (rank : 35)
Query Neighborhood Hits 71 Target Neighborhood Hits 597 Shared Neighborhood Hits 10
SwissProt Accessions Q80ST9, Q9CYM9, Q9D5J9 Gene names
Domain
Architecture

No domain graphic available

Description Protein C6orf152 homolog.
KIFA3_HUMAN
 
NC score 0.025892 (rank : 38) θ value 4.03905 (rank : 48)
Query Neighborhood Hits 71 Target Neighborhood Hits 29 Shared Neighborhood Hits 3
SwissProt Accessions Q92845, Q8NHU7, Q9H416 Gene names KIFAP3, SMAP
Domain
Architecture
Description Kinesin-associated protein 3 (Smg GDS-associated protein).
NR5A2_MOUSE
 
NC score 0.025852 (rank : 39) θ value 0.0736092 (rank : 31)
Query Neighborhood Hits 71 Target Neighborhood Hits 107 Shared Neighborhood Hits 3
SwissProt Accessions P45448 Gene names Nr5a2, Lrh1
Domain
Architecture
Description Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).
PSMD2_HUMAN
 
NC score 0.019478 (rank : 40) θ value 4.03905 (rank : 49)
Query Neighborhood Hits 71 Target Neighborhood Hits 88 Shared Neighborhood Hits 4
SwissProt Accessions Q13200, Q12932, Q15321, Q96I12 Gene names PSMD2, TRAP2
Domain
Architecture

No domain graphic available

Description 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Tumor necrosis factor type 1 receptor- associated protein 2) (55.11 protein).
MDN1_HUMAN
 
NC score 0.019373 (rank : 41) θ value 1.38821 (rank : 36)
Query Neighborhood Hits 71 Target Neighborhood Hits 662 Shared Neighborhood Hits 7
SwissProt Accessions Q9NU22, O15019 Gene names MDN1, KIAA0301
Domain
Architecture
Description Midasin (MIDAS-containing protein).
TCRG1_HUMAN
 
NC score 0.019159 (rank : 42) θ value 4.03905 (rank : 51)
Query Neighborhood Hits 71 Target Neighborhood Hits 929 Shared Neighborhood Hits 14
SwissProt Accessions O14776 Gene names TCERG1, CA150, TAF2S
Domain
Architecture

No domain graphic available

Description Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).
CF152_HUMAN
 
NC score 0.017758 (rank : 43) θ value 2.36792 (rank : 40)
Query Neighborhood Hits 71 Target Neighborhood Hits 704 Shared Neighborhood Hits 10
SwissProt Accessions Q86VQ0, Q9BWX7 Gene names C6orf152
Domain
Architecture

No domain graphic available

Description Protein C6orf152.
PSMD2_MOUSE
 
NC score 0.017455 (rank : 44) θ value 6.88961 (rank : 62)
Query Neighborhood Hits 71 Target Neighborhood Hits 147 Shared Neighborhood Hits 6
SwissProt Accessions Q8VDM4 Gene names Psmd2
Domain
Architecture

No domain graphic available

Description 26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).
INSC_HUMAN
 
NC score 0.016766 (rank : 45) θ value 4.03905 (rank : 47)
Query Neighborhood Hits 71 Target Neighborhood Hits 17 Shared Neighborhood Hits 2
SwissProt Accessions Q1MX18, Q1MX19, Q3C1V6, Q4AC95, Q4AC96, Q4AC97, Q4AC98 Gene names INSC
Domain
Architecture

No domain graphic available

Description Protein inscuteable homolog.
TCF25_HUMAN
 
NC score 0.016201 (rank : 46) θ value 4.03905 (rank : 50)
Query Neighborhood Hits 71 Target Neighborhood Hits 19 Shared Neighborhood Hits 2
SwissProt Accessions Q9BQ70, Q2MK75, Q9UPV3 Gene names TCF25, KIAA1049, NULP1
Domain
Architecture
Description Transcription factor 25 (Nuclear localized protein 1).
PARVG_HUMAN
 
NC score 0.015465 (rank : 47) θ value 5.27518 (rank : 58)
Query Neighborhood Hits 71 Target Neighborhood Hits 44 Shared Neighborhood Hits 3
SwissProt Accessions Q9HBI0, Q9BQX5, Q9NSG1 Gene names PARVG
Domain
Architecture
Description Gamma-parvin.
TCRG1_MOUSE
 
NC score 0.015233 (rank : 48) θ value 4.03905 (rank : 52)
Query Neighborhood Hits 71 Target Neighborhood Hits 947 Shared Neighborhood Hits 11
SwissProt Accessions Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5 Gene names Tcerg1, Taf2s
Domain
Architecture

No domain graphic available

Description Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).
ALS2_MOUSE
 
NC score 0.015016 (rank : 49) θ value 4.03905 (rank : 45)
Query Neighborhood Hits 71 Target Neighborhood Hits 111 Shared Neighborhood Hits 4
SwissProt Accessions Q920R0, Q8JZR1, Q9CXJ3 Gene names Als2
Domain
Architecture
Description Alsin (Amyotrophic lateral sclerosis protein 2 homolog).
ALS2_HUMAN
 
NC score 0.013993 (rank : 50) θ value 5.27518 (rank : 55)
Query Neighborhood Hits 71 Target Neighborhood Hits 121 Shared Neighborhood Hits 4
SwissProt Accessions Q96Q42, Q8N1E0, Q96PC4, Q96Q41, Q9H973, Q9HCK9 Gene names ALS2, KIAA1563
Domain
Architecture
Description Alsin (Amyotrophic lateral sclerosis protein 2).
TBL3_HUMAN
 
NC score 0.013778 (rank : 51) θ value 1.38821 (rank : 38)
Query Neighborhood Hits 71 Target Neighborhood Hits 286 Shared Neighborhood Hits 3
SwissProt Accessions Q12788 Gene names TBL3, SAZD
Domain
Architecture
Description WD repeat protein SAZD (Transducin beta-like 3 protein).
SMC2_MOUSE
 
NC score 0.013215 (rank : 52) θ value 8.99809 (rank : 69)
Query Neighborhood Hits 71 Target Neighborhood Hits 1131 Shared Neighborhood Hits 14
SwissProt Accessions Q8CG48, Q61076, Q9CS17, Q9CSD8 Gene names Smc2l1, Cape, Fin16, Smc2
Domain
Architecture
Description Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).
SMC2_HUMAN
 
NC score 0.012542 (rank : 53) θ value 6.88961 (rank : 63)
Query Neighborhood Hits 71 Target Neighborhood Hits 1405 Shared Neighborhood Hits 18
SwissProt Accessions O95347, Q9P1P2 Gene names SMC2L1, CAPE, SMC2
Domain
Architecture
Description Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).
GATB_HUMAN
 
NC score 0.012325 (rank : 54) θ value 6.88961 (rank : 60)
Query Neighborhood Hits 71 Target Neighborhood Hits 8 Shared Neighborhood Hits 2
SwissProt Accessions O75879, Q9P0S6, Q9Y2B8 Gene names PET112L, PET112
Domain
Architecture
Description Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial precursor (EC 6.3.5.-) (Glu-ADT subunit B) (Cytochrome oxidase assembly factor PET112 homolog).
CTND1_HUMAN
 
NC score 0.011437 (rank : 55) θ value 3.0926 (rank : 41)
Query Neighborhood Hits 71 Target Neighborhood Hits 67 Shared Neighborhood Hits 3
SwissProt Accessions O60716, O15088, O60713, O60714, O60715, O60935, Q6RBX8, Q9UP71, Q9UP72, Q9UP73 Gene names CTNND1, KIAA0384
Domain
Architecture
Description Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).
ABCC8_HUMAN
 
NC score 0.011167 (rank : 56) θ value 1.81305 (rank : 39)
Query Neighborhood Hits 71 Target Neighborhood Hits 118 Shared Neighborhood Hits 4
SwissProt Accessions Q09428, O75948, Q16583 Gene names ABCC8, SUR, SUR1
Domain
Architecture
Description ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).
SYNE1_HUMAN
 
NC score 0.009957 (rank : 57) θ value 3.0926 (rank : 43)
Query Neighborhood Hits 71 Target Neighborhood Hits 1484 Shared Neighborhood Hits 15
SwissProt Accessions Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8 Gene names SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain
Architecture
Description Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).
ICAM1_MOUSE
 
NC score 0.009522 (rank : 58) θ value 5.27518 (rank : 57)
Query Neighborhood Hits 71 Target Neighborhood Hits 99 Shared Neighborhood Hits 2
SwissProt Accessions P13597, Q61828 Gene names Icam1, Icam-1
Domain
Architecture
Description Intercellular adhesion molecule 1 precursor (ICAM-1) (MALA-2).
TTBK2_HUMAN
 
NC score 0.009157 (rank : 59) θ value 3.0926 (rank : 44)
Query Neighborhood Hits 71 Target Neighborhood Hits 822 Shared Neighborhood Hits 8
SwissProt Accessions Q6IQ55, O94932, Q6ZN52, Q8IVV1 Gene names TTBK2, KIAA0847
Domain
Architecture

No domain graphic available

Description Tau-tubulin kinase 2 (EC 2.7.11.1).
CTND1_MOUSE
 
NC score 0.008830 (rank : 60) θ value 8.99809 (rank : 65)
Query Neighborhood Hits 71 Target Neighborhood Hits 69 Shared Neighborhood Hits 3
SwissProt Accessions P30999 Gene names Ctnnd1, Catns
Domain
Architecture
Description Catenin delta-1 (p120 catenin) (p120(ctn)) (Cadherin-associated Src substrate) (CAS) (p120(cas)).
GOGA4_MOUSE
 
NC score 0.008136 (rank : 61) θ value 8.99809 (rank : 67)
Query Neighborhood Hits 71 Target Neighborhood Hits 1939 Shared Neighborhood Hits 17
SwissProt Accessions Q91VW5, O70365, Q8CGH6 Gene names Golga4
Domain
Architecture
Description Golgin subfamily A member 4 (tGolgin-1).
CCD46_HUMAN
 
NC score 0.008135 (rank : 62) θ value 4.03905 (rank : 46)
Query Neighborhood Hits 71 Target Neighborhood Hits 1430 Shared Neighborhood Hits 16
SwissProt Accessions Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4 Gene names CCDC46
Domain
Architecture

No domain graphic available

Description Coiled-coil domain-containing protein 46.
PDE6C_HUMAN
 
NC score 0.006777 (rank : 63) θ value 6.88961 (rank : 61)
Query Neighborhood Hits 71 Target Neighborhood Hits 56 Shared Neighborhood Hits 3
SwissProt Accessions P51160, Q5VY29 Gene names PDE6C, PDEA2
Domain
Architecture
Description Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).
SORT_MOUSE
 
NC score 0.006091 (rank : 64) θ value 8.99809 (rank : 70)
Query Neighborhood Hits 71 Target Neighborhood Hits 13 Shared Neighborhood Hits 2
SwissProt Accessions Q6PHU5, Q3UHE2, Q8K043, Q9QXW6 Gene names Sort1
Domain
Architecture

No domain graphic available

Description Sortilin precursor (Neurotensin receptor 3) (NTR3) (mNTR3).
CP250_MOUSE
 
NC score 0.005526 (rank : 65) θ value 5.27518 (rank : 56)
Query Neighborhood Hits 71 Target Neighborhood Hits 1583 Shared Neighborhood Hits 15
SwissProt Accessions Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6 Gene names Cep250, Cep2, Inmp
Domain
Architecture

No domain graphic available

Description Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).
TTBK2_MOUSE
 
NC score 0.003375 (rank : 66) θ value 8.99809 (rank : 71)
Query Neighborhood Hits 71 Target Neighborhood Hits 811 Shared Neighborhood Hits 7
SwissProt Accessions Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8 Gene names Ttbk2, Kiaa0847, Ttbk1
Domain
Architecture

No domain graphic available

Description Tau-tubulin kinase 2.
ANR32_MOUSE
 
NC score 0.003182 (rank : 67) θ value 8.99809 (rank : 64)
Query Neighborhood Hits 71 Target Neighborhood Hits 285 Shared Neighborhood Hits 2
SwissProt Accessions Q8R3P9, Q5XK30, Q8BHY5, Q921Y9 Gene names Ankrd32
Domain
Architecture

No domain graphic available

Description Ankyrin repeat domain-containing protein 32.
ULK4_MOUSE
 
NC score 0.000722 (rank : 68) θ value 4.03905 (rank : 54)
Query Neighborhood Hits 71 Target Neighborhood Hits 793 Shared Neighborhood Hits 8
SwissProt Accessions Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6 Gene names Ulk4
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).
MK12_HUMAN
 
NC score -0.000285 (rank : 69) θ value 3.0926 (rank : 42)
Query Neighborhood Hits 71 Target Neighborhood Hits 830 Shared Neighborhood Hits 7
SwissProt Accessions P53778, Q14260, Q99588, Q99672 Gene names MAPK12, ERK6, SAPK3
Domain
Architecture
Description Mitogen-activated protein kinase 12 (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (ERK5) (Stress-activated protein kinase 3) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma).
STK36_HUMAN
 
NC score -0.001099 (rank : 70) θ value 5.27518 (rank : 59)
Query Neighborhood Hits 71 Target Neighborhood Hits 896 Shared Neighborhood Hits 8
SwissProt Accessions Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2 Gene names STK36, KIAA1278
Domain
Architecture

No domain graphic available

Description Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).
NEK1_MOUSE
 
NC score -0.001659 (rank : 71) θ value 8.99809 (rank : 68)
Query Neighborhood Hits 71 Target Neighborhood Hits 1311 Shared Neighborhood Hits 13
SwissProt Accessions P51954 Gene names Nek1
Domain
Architecture
Description Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).