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Network neighborhood for query Sequence : KIFA3_HUMAN

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KIFA3_HUMAN
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KIFA3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	29	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).

KIFA3_MOUSE
θ value	0 (rank : 2)	NC score	0.998473 (rank : 2)
Query Neighborhood Hits	29	Target Neighborhood Hits	24	Shared Neighborhood Hits	21
SwissProt Accessions	P70188, P70189	Gene names	Kifap3
Domain Architecture
Description	Kinesin-associated protein 3 (KAP3).

CP250_HUMAN
θ value	0.21417 (rank : 3)	NC score	0.028763 (rank : 10)
Query Neighborhood Hits	29	Target Neighborhood Hits	1805	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

SSRP1_HUMAN
θ value	0.47712 (rank : 4)	NC score	0.058668 (rank : 4)
Query Neighborhood Hits	29	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

GOGA6_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.036443 (rank : 6)
Query Neighborhood Hits	29	Target Neighborhood Hits	1007	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

ARMC4_HUMAN
θ value	1.38821 (rank : 6)	NC score	0.060566 (rank : 3)
Query Neighborhood Hits	29	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

CENPE_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.017575 (rank : 23)
Query Neighborhood Hits	29	Target Neighborhood Hits	2060	Shared Neighborhood Hits	18
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RENT1_HUMAN
θ value	1.38821 (rank : 8)	NC score	0.024417 (rank : 14)
Query Neighborhood Hits	29	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

SSRP1_MOUSE
θ value	1.38821 (rank : 9)	NC score	0.050734 (rank : 5)
Query Neighborhood Hits	29	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

ROCK2_MOUSE
θ value	1.81305 (rank : 10)	NC score	0.012879 (rank : 26)
Query Neighborhood Hits	29	Target Neighborhood Hits	2072	Shared Neighborhood Hits	17
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

ROCK2_HUMAN
θ value	2.36792 (rank : 11)	NC score	0.012317 (rank : 27)
Query Neighborhood Hits	29	Target Neighborhood Hits	2073	Shared Neighborhood Hits	15
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ATR_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.031834 (rank : 9)
Query Neighborhood Hits	29	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

ITSN2_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.018111 (rank : 21)
Query Neighborhood Hits	29	Target Neighborhood Hits	1371	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MORC4_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.031989 (rank : 8)
Query Neighborhood Hits	29	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

ATR_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.025892 (rank : 12)
Query Neighborhood Hits	29	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q13535, Q7KYL3, Q93051, Q9BXK4	Gene names	ATR, FRP1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).

CEP63_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.021416 (rank : 18)
Query Neighborhood Hits	29	Target Neighborhood Hits	1005	Shared Neighborhood Hits	14
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

DNJCD_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.025046 (rank : 13)
Query Neighborhood Hits	29	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	O75165, Q6PI82, Q6UJ77, Q6ZSW1, Q6ZUT5, Q86XG3, Q96DC1, Q9BWK9	Gene names	DNAJC13, KIAA0678, RME8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8).

MACF1_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.020012 (rank : 19)
Query Neighborhood Hits	29	Target Neighborhood Hits	1341	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.022653 (rank : 16)
Query Neighborhood Hits	29	Target Neighborhood Hits	1321	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

RFC1_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.017224 (rank : 24)
Query Neighborhood Hits	29	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

T3JAM_MOUSE
θ value	5.27518 (rank : 21)	NC score	0.032713 (rank : 7)
Query Neighborhood Hits	29	Target Neighborhood Hits	535	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

GLE1_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.024070 (rank : 15)
Query Neighborhood Hits	29	Target Neighborhood Hits	445	Shared Neighborhood Hits	9
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

IREB1_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.022069 (rank : 17)
Query Neighborhood Hits	29	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P21399, Q14652	Gene names	ACO1, IREB1
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

SM1L2_MOUSE
θ value	6.88961 (rank : 24)	NC score	0.019653 (rank : 20)
Query Neighborhood Hits	29	Target Neighborhood Hits	918	Shared Neighborhood Hits	14
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

ANR18_HUMAN
θ value	8.99809 (rank : 25)	NC score	0.009389 (rank : 28)
Query Neighborhood Hits	29	Target Neighborhood Hits	1106	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

BIN3_MOUSE
θ value	8.99809 (rank : 26)	NC score	0.018066 (rank : 22)
Query Neighborhood Hits	29	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JI08	Gene names	Bin3
Domain Architecture	No domain graphic available
Description	Bridging integrator 3.

CO4A3_HUMAN
θ value	8.99809 (rank : 27)	NC score	0.003579 (rank : 29)
Query Neighborhood Hits	29	Target Neighborhood Hits	421	Shared Neighborhood Hits	2
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

IREB1_MOUSE
θ value	8.99809 (rank : 28)	NC score	0.016066 (rank : 25)
Query Neighborhood Hits	29	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P28271, Q99K54	Gene names	Aco1, Ireb1, Irebp
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

MIA2_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.028029 (rank : 11)
Query Neighborhood Hits	29	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

Hits sorted by NC score

KIFA3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	29	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).

KIFA3_MOUSE
NC score	0.998473 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	29	Target Neighborhood Hits	24	Shared Neighborhood Hits	21
SwissProt Accessions	P70188, P70189	Gene names	Kifap3
Domain Architecture
Description	Kinesin-associated protein 3 (KAP3).

ARMC4_HUMAN
NC score	0.060566 (rank : 3)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	29	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T2S8, Q9H0C0	Gene names	ARMC4
Domain Architecture	No domain graphic available
Description	Armadillo repeat-containing protein 4.

SSRP1_HUMAN
NC score	0.058668 (rank : 4)	θ value	0.47712 (rank : 4)
Query Neighborhood Hits	29	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

SSRP1_MOUSE
NC score	0.050734 (rank : 5)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	29	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

GOGA6_HUMAN
NC score	0.036443 (rank : 6)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	29	Target Neighborhood Hits	1007	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

T3JAM_MOUSE
NC score	0.032713 (rank : 7)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	29	Target Neighborhood Hits	535	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

MORC4_HUMAN
NC score	0.031989 (rank : 8)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	29	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TE76, Q5JUK7, Q96MZ2, Q9HAI7	Gene names	MORC4, ZCWCC2
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 4 (Zinc finger CW-type coiled- coil domain protein 2).

ATR_MOUSE
NC score	0.031834 (rank : 9)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	29	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JKK8	Gene names	Atr
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein).

CP250_HUMAN
NC score	0.028763 (rank : 10)	θ value	0.21417 (rank : 3)
Query Neighborhood Hits	29	Target Neighborhood Hits	1805	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MIA2_MOUSE
NC score	0.028029 (rank : 11)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	29	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

ATR_HUMAN
NC score	0.025892 (rank : 12)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	29	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q13535, Q7KYL3, Q93051, Q9BXK4	Gene names	ATR, FRP1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1).

DNJCD_HUMAN
NC score	0.025046 (rank : 13)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	29	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	O75165, Q6PI82, Q6UJ77, Q6ZSW1, Q6ZUT5, Q86XG3, Q96DC1, Q9BWK9	Gene names	DNAJC13, KIAA0678, RME8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8).

RENT1_HUMAN
NC score	0.024417 (rank : 14)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	29	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

GLE1_HUMAN
NC score	0.024070 (rank : 15)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	29	Target Neighborhood Hits	445	Shared Neighborhood Hits	9
SwissProt Accessions	Q53GS7, O75458, Q53GT9, Q5VVU1, Q8NCP6, Q9UFL6	Gene names	GLE1L, GLE1
Domain Architecture	No domain graphic available
Description	Nucleoporin GLE1 (GLE1-like protein) (hGLE1).

MACF4_HUMAN
NC score	0.022653 (rank : 16)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	29	Target Neighborhood Hits	1321	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

IREB1_HUMAN
NC score	0.022069 (rank : 17)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	29	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	P21399, Q14652	Gene names	ACO1, IREB1
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

CEP63_HUMAN
NC score	0.021416 (rank : 18)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	29	Target Neighborhood Hits	1005	Shared Neighborhood Hits	14
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

MACF1_HUMAN
NC score	0.020012 (rank : 19)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	29	Target Neighborhood Hits	1341	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

SM1L2_MOUSE
NC score	0.019653 (rank : 20)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	29	Target Neighborhood Hits	918	Shared Neighborhood Hits	14
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

ITSN2_MOUSE
NC score	0.018111 (rank : 21)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	29	Target Neighborhood Hits	1371	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

BIN3_MOUSE
NC score	0.018066 (rank : 22)	θ value	8.99809 (rank : 26)
Query Neighborhood Hits	29	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JI08	Gene names	Bin3
Domain Architecture	No domain graphic available
Description	Bridging integrator 3.

CENPE_HUMAN
NC score	0.017575 (rank : 23)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	29	Target Neighborhood Hits	2060	Shared Neighborhood Hits	18
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RFC1_HUMAN
NC score	0.017224 (rank : 24)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	29	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

IREB1_MOUSE
NC score	0.016066 (rank : 25)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	29	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P28271, Q99K54	Gene names	Aco1, Ireb1, Irebp
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

ROCK2_MOUSE
NC score	0.012879 (rank : 26)	θ value	1.81305 (rank : 10)
Query Neighborhood Hits	29	Target Neighborhood Hits	2072	Shared Neighborhood Hits	17
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

ROCK2_HUMAN
NC score	0.012317 (rank : 27)	θ value	2.36792 (rank : 11)
Query Neighborhood Hits	29	Target Neighborhood Hits	2073	Shared Neighborhood Hits	15
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ANR18_HUMAN
NC score	0.009389 (rank : 28)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	29	Target Neighborhood Hits	1106	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

CO4A3_HUMAN
NC score	0.003579 (rank : 29)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	29	Target Neighborhood Hits	421	Shared Neighborhood Hits	2
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).