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Network neighborhood for query Sequence : IREB1_HUMAN

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IREB1_HUMAN
SwissProt Accessions	P21399, Q14652	Gene names	ACO1, IREB1
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IREB1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P21399, Q14652	Gene names	ACO1, IREB1
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

IREB1_MOUSE
θ value	0 (rank : 2)	NC score	0.999787 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P28271, Q99K54	Gene names	Aco1, Ireb1, Irebp
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

IREB2_HUMAN
θ value	0 (rank : 3)	NC score	0.988347 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P48200, Q13095	Gene names	IREB2
Domain Architecture
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

IREB2_MOUSE
θ value	0 (rank : 4)	NC score	0.988410 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q811J3, O70235	Gene names	Ireb2, Irp2
Domain Architecture	No domain graphic available
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

ACON_HUMAN
θ value	6.14528e-49 (rank : 5)	NC score	0.793021 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q99798, O75809	Gene names	ACO2
Domain Architecture
Description	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

ACON_MOUSE
θ value	6.7944e-48 (rank : 6)	NC score	0.792442 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KI0	Gene names	Aco2
Domain Architecture	No domain graphic available
Description	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

KIFA3_HUMAN
θ value	6.88961 (rank : 7)	NC score	0.022069 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).

AL2S8_HUMAN
θ value	8.99809 (rank : 8)	NC score	0.015656 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N187, Q8ND29, Q8WXC0, Q96J78, Q96Q38, Q96Q39, Q9H712	Gene names	ALS2CR8, CARF
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24).

I27RA_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.008566 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

KIFA3_MOUSE
θ value	8.99809 (rank : 10)	NC score	0.015876 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P70188, P70189	Gene names	Kifap3
Domain Architecture
Description	Kinesin-associated protein 3 (KAP3).

Hits sorted by NC score

IREB1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P21399, Q14652	Gene names	ACO1, IREB1
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

IREB1_MOUSE
NC score	0.999787 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P28271, Q99K54	Gene names	Aco1, Ireb1, Irebp
Domain Architecture
Description	Iron-responsive element-binding protein 1 (IRE-BP 1) (Iron regulatory protein 1) (IRP1) (Ferritin repressor protein) (Aconitate hydratase) (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

IREB2_MOUSE
NC score	0.988410 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q811J3, O70235	Gene names	Ireb2, Irp2
Domain Architecture	No domain graphic available
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

IREB2_HUMAN
NC score	0.988347 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P48200, Q13095	Gene names	IREB2
Domain Architecture
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

ACON_HUMAN
NC score	0.793021 (rank : 5)	θ value	6.14528e-49 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q99798, O75809	Gene names	ACO2
Domain Architecture
Description	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

ACON_MOUSE
NC score	0.792442 (rank : 6)	θ value	6.7944e-48 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KI0	Gene names	Aco2
Domain Architecture	No domain graphic available
Description	Aconitate hydratase, mitochondrial precursor (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase).

KIFA3_HUMAN
NC score	0.022069 (rank : 7)	θ value	6.88961 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q92845, Q8NHU7, Q9H416	Gene names	KIFAP3, SMAP
Domain Architecture
Description	Kinesin-associated protein 3 (Smg GDS-associated protein).

KIFA3_MOUSE
NC score	0.015876 (rank : 8)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P70188, P70189	Gene names	Kifap3
Domain Architecture
Description	Kinesin-associated protein 3 (KAP3).

AL2S8_HUMAN
NC score	0.015656 (rank : 9)	θ value	8.99809 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N187, Q8ND29, Q8WXC0, Q96J78, Q96Q38, Q96Q39, Q9H712	Gene names	ALS2CR8, CARF
Domain Architecture	No domain graphic available
Description	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein (Calcium-response factor) (CaRF) (Testis development protein NYD-SP24).

I27RA_HUMAN
NC score	0.008566 (rank : 10)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).