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Network neighborhood for query Sequence : P3H2_MOUSE

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P3H2_MOUSE
SwissProt Accessions	Q8CG71, Q8C673	Gene names	Leprel1, P3h2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

P3H2_HUMAN
θ value	0 (rank : 1)	NC score	0.998603 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IVL5, Q9NVI2	Gene names	LEPREL1, MLAT4, P3H2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4).

P3H2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CG71, Q8C673	Gene names	Leprel1, P3h2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1).

P3H1_MOUSE
θ value	2.32313e-181 (rank : 3)	NC score	0.983182 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q3V1T4, Q3TWX8, Q8BSV2, Q8CFL3, Q9CWK5, Q9QZT6, Q9QZT7	Gene names	Lepre1, Gros1, P3h1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

P3H1_HUMAN
θ value	3.5924e-174 (rank : 4)	NC score	0.981997 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q32P28, Q7KZR4, Q96BR8, Q96SK8, Q96SL5, Q96SN3, Q9H6K3, Q9HC86, Q9HC87	Gene names	LEPRE1, GROS1, P3H1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

P3H3_HUMAN
θ value	3.08376e-125 (rank : 5)	NC score	0.965996 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IVL6, Q13512, Q15740, Q66K32, Q6NX61, Q7L2T1	Gene names	LEPREL2, P3H3
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 3 precursor (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B).

P3H3_MOUSE
θ value	1.17183e-124 (rank : 6)	NC score	0.964763 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CG70, O88836	Gene names	Leprel2, P3h3
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 3 precursor (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B).

CRTAP_HUMAN
θ value	7.51208e-47 (rank : 7)	NC score	0.865857 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	O75718	Gene names	CRTAP, CASP
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

CRTAP_MOUSE
θ value	1.56636e-44 (rank : 8)	NC score	0.857621 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CYD3, O88698	Gene names	Crtap, Casp
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

NO55_HUMAN
θ value	2.19584e-30 (rank : 9)	NC score	0.840322 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q92791, Q9H4F6	Gene names	SC65, NOL55
Domain Architecture	No domain graphic available
Description	Nucleolar autoantigen No55.

P4HA2_HUMAN
θ value	0.0736092 (rank : 10)	NC score	0.102718 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	O15460, Q8WWN0	Gene names	P4HA2
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-2 subunit precursor (EC 1.14.11.2) (4-PH alpha-2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-2 subunit).

DIAP2_MOUSE
θ value	0.125558 (rank : 11)	NC score	0.031885 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

EGLN1_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.084165 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

EGLN1_MOUSE
θ value	0.279714 (rank : 13)	NC score	0.083021 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	88	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

FKBP5_HUMAN
θ value	0.279714 (rank : 14)	NC score	0.029143 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q13451	Gene names	FKBP5, AIG6, FKBP51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51) (54 kDa progesterone receptor-associated immunophilin) (FKBP54) (P54) (FF1 antigen) (HSP90-binding immunophilin) (Androgen-regulated protein 6).

P4HA1_HUMAN
θ value	0.279714 (rank : 15)	NC score	0.088523 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	P13674, Q15082, Q15083, Q5VSQ5	Gene names	P4HA1, P4HA
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-1 subunit precursor (EC 1.14.11.2) (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-1 subunit).

P4HA1_MOUSE
θ value	0.279714 (rank : 16)	NC score	0.084627 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q60715, Q3TEB7, Q80T05, Q91VJ7	Gene names	P4ha1
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-1 subunit precursor (EC 1.14.11.2) (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-1 subunit).

P4HA2_MOUSE
θ value	0.279714 (rank : 17)	NC score	0.121824 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q60716, Q8VBU4	Gene names	P4ha2
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-2 subunit precursor (EC 1.14.11.2) (4-PH alpha-2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-2 subunit).

CF058_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.032780 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P5S2, Q5VUP2	Gene names	C6orf58
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf58 precursor.

EGLN2_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.079510 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KS0, Q8WWY4, Q9BV14	Gene names	EGLN2, EIT6
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (HPH-3) (Prolyl hydroxylase domain-containing protein 1) (PHD1) (Estrogen-induced tag 6).

EGLN2_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.087015 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE2, Q8C6I4, Q8CIL9, Q8VHJ1, Q99MI0	Gene names	Egln2
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (Falkor).

FKBP5_MOUSE
θ value	1.06291 (rank : 21)	NC score	0.027509 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q64378	Gene names	Fkbp5, Fkbp51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51).

ROCK1_MOUSE
θ value	1.81305 (rank : 22)	NC score	-0.000165 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	2126	Shared Neighborhood Hits	6
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

TNFL6_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.019518 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	P41047, Q61217, Q9R1F2	Gene names	Faslg, Apt1lg1, Fasl, gld, Tnfsf6
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 6 (Fas antigen ligand) (Fas ligand) (CD178 antigen) (CD95L protein) [Contains: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form].

IMB1_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.029763 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

IMB1_MOUSE
θ value	4.03905 (rank : 25)	NC score	0.029882 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

AKAP9_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.006881 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	1710	Shared Neighborhood Hits	8
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

PDE4B_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.007248 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q07343, O15443	Gene names	PDE4B
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.17) (DPDE4) (PDE32).

EGLN3_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.058966 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H6Z9	Gene names	EGLN3
Domain Architecture
Description	Egl nine homolog 3 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-prolyl hydroxylase 3) (HIF-PH3) (HPH-1) (Prolyl hydroxylase domain-containing protein 3) (PHD3).

EGLN3_MOUSE
θ value	6.88961 (rank : 29)	NC score	0.058955 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q91UZ4, Q3TCG8, Q8C8M6, Q8CCA8, Q8R5C7	Gene names	Egln3
Domain Architecture
Description	Egl nine homolog 3 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-prolyl hydroxylase 3) (HIF-PH3) (SM-20).

LRP1B_MOUSE
θ value	6.88961 (rank : 30)	NC score	0.001470 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	606	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

DIAP2_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.013876 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

DMD_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.001660 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	1111	Shared Neighborhood Hits	5
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

MRCKB_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.000673 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	2239	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

UTP15_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.002524 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	296	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

Hits sorted by NC score

P3H2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CG71, Q8C673	Gene names	Leprel1, P3h2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1).

P3H2_HUMAN
NC score	0.998603 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IVL5, Q9NVI2	Gene names	LEPREL1, MLAT4, P3H2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4).

P3H1_MOUSE
NC score	0.983182 (rank : 3)	θ value	2.32313e-181 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	37	Shared Neighborhood Hits	19
SwissProt Accessions	Q3V1T4, Q3TWX8, Q8BSV2, Q8CFL3, Q9CWK5, Q9QZT6, Q9QZT7	Gene names	Lepre1, Gros1, P3h1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

P3H1_HUMAN
NC score	0.981997 (rank : 4)	θ value	3.5924e-174 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	18
SwissProt Accessions	Q32P28, Q7KZR4, Q96BR8, Q96SK8, Q96SL5, Q96SN3, Q9H6K3, Q9HC86, Q9HC87	Gene names	LEPRE1, GROS1, P3H1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

P3H3_HUMAN
NC score	0.965996 (rank : 5)	θ value	3.08376e-125 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IVL6, Q13512, Q15740, Q66K32, Q6NX61, Q7L2T1	Gene names	LEPREL2, P3H3
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 3 precursor (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B).

P3H3_MOUSE
NC score	0.964763 (rank : 6)	θ value	1.17183e-124 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CG70, O88836	Gene names	Leprel2, P3h3
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 3 precursor (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B).

CRTAP_HUMAN
NC score	0.865857 (rank : 7)	θ value	7.51208e-47 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	O75718	Gene names	CRTAP, CASP
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

CRTAP_MOUSE
NC score	0.857621 (rank : 8)	θ value	1.56636e-44 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CYD3, O88698	Gene names	Crtap, Casp
Domain Architecture	No domain graphic available
Description	Cartilage-associated protein precursor.

NO55_HUMAN
NC score	0.840322 (rank : 9)	θ value	2.19584e-30 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	16	Shared Neighborhood Hits	12
SwissProt Accessions	Q92791, Q9H4F6	Gene names	SC65, NOL55
Domain Architecture	No domain graphic available
Description	Nucleolar autoantigen No55.

P4HA2_MOUSE
NC score	0.121824 (rank : 10)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	18	Shared Neighborhood Hits	9
SwissProt Accessions	Q60716, Q8VBU4	Gene names	P4ha2
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-2 subunit precursor (EC 1.14.11.2) (4-PH alpha-2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-2 subunit).

P4HA2_HUMAN
NC score	0.102718 (rank : 11)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	O15460, Q8WWN0	Gene names	P4HA2
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-2 subunit precursor (EC 1.14.11.2) (4-PH alpha-2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-2 subunit).

P4HA1_HUMAN
NC score	0.088523 (rank : 12)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	22	Shared Neighborhood Hits	9
SwissProt Accessions	P13674, Q15082, Q15083, Q5VSQ5	Gene names	P4HA1, P4HA
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-1 subunit precursor (EC 1.14.11.2) (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-1 subunit).

EGLN2_MOUSE
NC score	0.087015 (rank : 13)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	14	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE2, Q8C6I4, Q8CIL9, Q8VHJ1, Q99MI0	Gene names	Egln2
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (Falkor).

P4HA1_MOUSE
NC score	0.084627 (rank : 14)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q60715, Q3TEB7, Q80T05, Q91VJ7	Gene names	P4ha1
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-1 subunit precursor (EC 1.14.11.2) (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-1 subunit).

EGLN1_HUMAN
NC score	0.084165 (rank : 15)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	61	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

EGLN1_MOUSE
NC score	0.083021 (rank : 16)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	88	Shared Neighborhood Hits	10
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

EGLN2_HUMAN
NC score	0.079510 (rank : 17)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KS0, Q8WWY4, Q9BV14	Gene names	EGLN2, EIT6
Domain Architecture
Description	Egl nine homolog 2 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 1) (HIF-prolyl hydroxylase 1) (HIF-PH1) (HPH-3) (Prolyl hydroxylase domain-containing protein 1) (PHD1) (Estrogen-induced tag 6).

EGLN3_HUMAN
NC score	0.058966 (rank : 18)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H6Z9	Gene names	EGLN3
Domain Architecture
Description	Egl nine homolog 3 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-prolyl hydroxylase 3) (HIF-PH3) (HPH-1) (Prolyl hydroxylase domain-containing protein 3) (PHD3).

EGLN3_MOUSE
NC score	0.058955 (rank : 19)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q91UZ4, Q3TCG8, Q8C8M6, Q8CCA8, Q8R5C7	Gene names	Egln3
Domain Architecture
Description	Egl nine homolog 3 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-prolyl hydroxylase 3) (HIF-PH3) (SM-20).

CF058_HUMAN
NC score	0.032780 (rank : 20)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P5S2, Q5VUP2	Gene names	C6orf58
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf58 precursor.

DIAP2_MOUSE
NC score	0.031885 (rank : 21)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

IMB1_MOUSE
NC score	0.029882 (rank : 22)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

IMB1_HUMAN
NC score	0.029763 (rank : 23)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

FKBP5_HUMAN
NC score	0.029143 (rank : 24)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q13451	Gene names	FKBP5, AIG6, FKBP51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51) (54 kDa progesterone receptor-associated immunophilin) (FKBP54) (P54) (FF1 antigen) (HSP90-binding immunophilin) (Androgen-regulated protein 6).

FKBP5_MOUSE
NC score	0.027509 (rank : 25)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q64378	Gene names	Fkbp5, Fkbp51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51).

TNFL6_MOUSE
NC score	0.019518 (rank : 26)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	P41047, Q61217, Q9R1F2	Gene names	Faslg, Apt1lg1, Fasl, gld, Tnfsf6
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 6 (Fas antigen ligand) (Fas ligand) (CD178 antigen) (CD95L protein) [Contains: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form].

DIAP2_HUMAN
NC score	0.013876 (rank : 27)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

PDE4B_HUMAN
NC score	0.007248 (rank : 28)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	Q07343, O15443	Gene names	PDE4B
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.17) (DPDE4) (PDE32).

AKAP9_HUMAN
NC score	0.006881 (rank : 29)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	1710	Shared Neighborhood Hits	8
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

UTP15_HUMAN
NC score	0.002524 (rank : 30)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	296	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TED0, Q6IA60, Q96E08, Q9H9F8	Gene names	UTP15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog.

DMD_MOUSE
NC score	0.001660 (rank : 31)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	1111	Shared Neighborhood Hits	5
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

LRP1B_MOUSE
NC score	0.001470 (rank : 32)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	606	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MRCKB_HUMAN
NC score	0.000673 (rank : 33)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	2239	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ROCK1_MOUSE
NC score	-0.000165 (rank : 34)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	2126	Shared Neighborhood Hits	6
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).