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Network neighborhood for query Sequence : P4HA1_HUMAN

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P4HA1_HUMAN
SwissProt Accessions	P13674, Q15082, Q15083, Q5VSQ5	Gene names	P4HA1, P4HA
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-1 subunit precursor (EC 1.14.11.2) (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-1 subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

P4HA1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	P13674, Q15082, Q15083, Q5VSQ5	Gene names	P4HA1, P4HA
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-1 subunit precursor (EC 1.14.11.2) (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-1 subunit).

P4HA1_MOUSE
θ value	0 (rank : 2)	NC score	0.999359 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	19
SwissProt Accessions	Q60715, Q3TEB7, Q80T05, Q91VJ7	Gene names	P4ha1
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-1 subunit precursor (EC 1.14.11.2) (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-1 subunit).

P4HA2_HUMAN
θ value	0 (rank : 3)	NC score	0.990106 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	O15460, Q8WWN0	Gene names	P4HA2
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-2 subunit precursor (EC 1.14.11.2) (4-PH alpha-2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-2 subunit).

P4HA2_MOUSE
θ value	0 (rank : 4)	NC score	0.989933 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q60716, Q8VBU4	Gene names	P4ha2
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-2 subunit precursor (EC 1.14.11.2) (4-PH alpha-2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-2 subunit).

EGLX_MOUSE
θ value	1.86753e-13 (rank : 5)	NC score	0.520766 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BG58, Q8CAF1, Q9D499	Gene names	Ph4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

EGLX_HUMAN
θ value	2.43908e-13 (rank : 6)	NC score	0.521692 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NXG6, Q6PAG6, Q8TCJ9, Q8WV55, Q96F22, Q9BW77	Gene names	PH4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

P3H2_MOUSE
θ value	0.279714 (rank : 7)	NC score	0.088523 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	34	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CG71, Q8C673	Gene names	Leprel1, P3h2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1).

P3H2_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.086475 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IVL5, Q9NVI2	Gene names	LEPREL1, MLAT4, P3H2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4).

DCTN2_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.069751 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q13561, Q86YN2, Q9BW17	Gene names	DCTN2, DCTN50
Domain Architecture
Description	Dynactin subunit 2 (Dynactin complex 50 kDa subunit) (50 kDa dynein- associated polypeptide) (p50 dynamitin) (DCTN-50).

LUZP1_HUMAN
θ value	1.38821 (rank : 10)	NC score	0.013854 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	739	Shared Neighborhood Hits	6
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

BPA1_MOUSE
θ value	1.81305 (rank : 11)	NC score	0.012947 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	1477	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

DCTN2_MOUSE
θ value	1.81305 (rank : 12)	NC score	0.061729 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KJ8	Gene names	Dctn2
Domain Architecture
Description	Dynactin subunit 2 (Dynactin complex 50 kDa subunit) (50 kDa dynein- associated polypeptide) (p50 dynamitin) (DCTN-50) (Growth cone membrane protein 23-48K) (GMP23-48K).

PCYOX_MOUSE
θ value	1.81305 (rank : 13)	NC score	0.070441 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

RFX1_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.028686 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	256	Shared Neighborhood Hits	5
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

P3H1_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.075340 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q3V1T4, Q3TWX8, Q8BSV2, Q8CFL3, Q9CWK5, Q9QZT6, Q9QZT7	Gene names	Lepre1, Gros1, P3h1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

RFX1_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.026617 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

P3H1_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.062703 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	Q32P28, Q7KZR4, Q96BR8, Q96SK8, Q96SL5, Q96SN3, Q9H6K3, Q9HC86, Q9HC87	Gene names	LEPRE1, GROS1, P3H1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

TRIPB_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.006415 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	1587	Shared Neighborhood Hits	6
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

BBS4_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.020707 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

BPAEA_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.011927 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	1369	Shared Neighborhood Hits	9
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

EEA1_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.006045 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	1796	Shared Neighborhood Hits	8
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

NO55_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.057859 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q92791, Q9H4F6	Gene names	SC65, NOL55
Domain Architecture	No domain graphic available
Description	Nucleolar autoantigen No55.

Hits sorted by NC score

P4HA1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	P13674, Q15082, Q15083, Q5VSQ5	Gene names	P4HA1, P4HA
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-1 subunit precursor (EC 1.14.11.2) (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-1 subunit).

P4HA1_MOUSE
NC score	0.999359 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	21	Shared Neighborhood Hits	19
SwissProt Accessions	Q60715, Q3TEB7, Q80T05, Q91VJ7	Gene names	P4ha1
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-1 subunit precursor (EC 1.14.11.2) (4-PH alpha-1) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-1 subunit).

P4HA2_HUMAN
NC score	0.990106 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	O15460, Q8WWN0	Gene names	P4HA2
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-2 subunit precursor (EC 1.14.11.2) (4-PH alpha-2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-2 subunit).

P4HA2_MOUSE
NC score	0.989933 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q60716, Q8VBU4	Gene names	P4ha2
Domain Architecture
Description	Prolyl 4-hydroxylase alpha-2 subunit precursor (EC 1.14.11.2) (4-PH alpha-2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase alpha-2 subunit).

EGLX_HUMAN
NC score	0.521692 (rank : 5)	θ value	2.43908e-13 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NXG6, Q6PAG6, Q8TCJ9, Q8WV55, Q96F22, Q9BW77	Gene names	PH4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

EGLX_MOUSE
NC score	0.520766 (rank : 6)	θ value	1.86753e-13 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BG58, Q8CAF1, Q9D499	Gene names	Ph4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

P3H2_MOUSE
NC score	0.088523 (rank : 7)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	34	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CG71, Q8C673	Gene names	Leprel1, P3h2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1).

P3H2_HUMAN
NC score	0.086475 (rank : 8)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IVL5, Q9NVI2	Gene names	LEPREL1, MLAT4, P3H2
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 2 precursor (EC 1.14.11.7) (Leprecan-like protein 1) (Myxoid liposarcoma-associated protein 4).

P3H1_MOUSE
NC score	0.075340 (rank : 9)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q3V1T4, Q3TWX8, Q8BSV2, Q8CFL3, Q9CWK5, Q9QZT6, Q9QZT7	Gene names	Lepre1, Gros1, P3h1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

PCYOX_MOUSE
NC score	0.070441 (rank : 10)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQF9, Q3UHV6, Q69ZW0, Q8BZX1	Gene names	Pcyox1, Kiaa0908
Domain Architecture	No domain graphic available
Description	Prenylcysteine oxidase precursor (EC 1.8.3.5).

DCTN2_HUMAN
NC score	0.069751 (rank : 11)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q13561, Q86YN2, Q9BW17	Gene names	DCTN2, DCTN50
Domain Architecture
Description	Dynactin subunit 2 (Dynactin complex 50 kDa subunit) (50 kDa dynein- associated polypeptide) (p50 dynamitin) (DCTN-50).

P3H1_HUMAN
NC score	0.062703 (rank : 12)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	Q32P28, Q7KZR4, Q96BR8, Q96SK8, Q96SL5, Q96SN3, Q9H6K3, Q9HC86, Q9HC87	Gene names	LEPRE1, GROS1, P3H1
Domain Architecture	No domain graphic available
Description	Prolyl 3-hydroxylase 1 precursor (EC 1.14.11.7) (Leucine- and proline- enriched proteoglycan 1) (Leprecan-1) (Growth suppressor 1).

DCTN2_MOUSE
NC score	0.061729 (rank : 13)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KJ8	Gene names	Dctn2
Domain Architecture
Description	Dynactin subunit 2 (Dynactin complex 50 kDa subunit) (50 kDa dynein- associated polypeptide) (p50 dynamitin) (DCTN-50) (Growth cone membrane protein 23-48K) (GMP23-48K).

NO55_HUMAN
NC score	0.057859 (rank : 14)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	8
SwissProt Accessions	Q92791, Q9H4F6	Gene names	SC65, NOL55
Domain Architecture	No domain graphic available
Description	Nucleolar autoantigen No55.

RFX1_HUMAN
NC score	0.028686 (rank : 15)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	256	Shared Neighborhood Hits	5
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

RFX1_MOUSE
NC score	0.026617 (rank : 16)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

BBS4_MOUSE
NC score	0.020707 (rank : 17)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

LUZP1_HUMAN
NC score	0.013854 (rank : 18)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	739	Shared Neighborhood Hits	6
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

BPA1_MOUSE
NC score	0.012947 (rank : 19)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	1477	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_HUMAN
NC score	0.011927 (rank : 20)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	1369	Shared Neighborhood Hits	9
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TRIPB_HUMAN
NC score	0.006415 (rank : 21)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	1587	Shared Neighborhood Hits	6
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

EEA1_HUMAN
NC score	0.006045 (rank : 22)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	1796	Shared Neighborhood Hits	8
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).