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Network neighborhood for query Sequence : TEX15_HUMAN

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TEX15_HUMAN
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TEX15_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

ATRX_HUMAN
θ value	0.000461057 (rank : 2)	NC score	0.113856 (rank : 4)
Query Neighborhood Hits	174	Target Neighborhood Hits	842	Shared Neighborhood Hits	63
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

AF9_HUMAN
θ value	0.00390308 (rank : 3)	NC score	0.126025 (rank : 3)
Query Neighborhood Hits	174	Target Neighborhood Hits	202	Shared Neighborhood Hits	17
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

PIBF1_HUMAN
θ value	0.0148317 (rank : 4)	NC score	0.071161 (rank : 12)
Query Neighborhood Hits	174	Target Neighborhood Hits	1041	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

CYLC1_HUMAN
θ value	0.0193708 (rank : 5)	NC score	0.126342 (rank : 2)
Query Neighborhood Hits	174	Target Neighborhood Hits	408	Shared Neighborhood Hits	46
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

LRRF1_HUMAN
θ value	0.0193708 (rank : 6)	NC score	0.100966 (rank : 6)
Query Neighborhood Hits	174	Target Neighborhood Hits	625	Shared Neighborhood Hits	42
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

NCOA3_HUMAN
θ value	0.0193708 (rank : 7)	NC score	0.059380 (rank : 35)
Query Neighborhood Hits	174	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

CENPE_HUMAN
θ value	0.0431538 (rank : 8)	NC score	0.060247 (rank : 30)
Query Neighborhood Hits	174	Target Neighborhood Hits	2060	Shared Neighborhood Hits	75
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

BRD4_MOUSE
θ value	0.0563607 (rank : 9)	NC score	0.060915 (rank : 27)
Query Neighborhood Hits	174	Target Neighborhood Hits	845	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CI084_HUMAN
θ value	0.0736092 (rank : 10)	NC score	0.101737 (rank : 5)
Query Neighborhood Hits	174	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VXU9, Q96M73	Gene names	C9orf84
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf84.

PDE1C_HUMAN
θ value	0.0736092 (rank : 11)	NC score	0.045678 (rank : 85)
Query Neighborhood Hits	174	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).

ASPM_MOUSE
θ value	0.0961366 (rank : 12)	NC score	0.066273 (rank : 19)
Query Neighborhood Hits	174	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

ESCO1_MOUSE
θ value	0.125558 (rank : 13)	NC score	0.068170 (rank : 16)
Query Neighborhood Hits	174	Target Neighborhood Hits	87	Shared Neighborhood Hits	13
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

SYNE2_HUMAN
θ value	0.125558 (rank : 14)	NC score	0.067784 (rank : 18)
Query Neighborhood Hits	174	Target Neighborhood Hits	1323	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

PLCD1_MOUSE
θ value	0.163984 (rank : 15)	NC score	0.051570 (rank : 70)
Query Neighborhood Hits	174	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PRP4B_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.024432 (rank : 135)
Query Neighborhood Hits	174	Target Neighborhood Hits	1040	Shared Neighborhood Hits	31
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

UBP1_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.067934 (rank : 17)
Query Neighborhood Hits	174	Target Neighborhood Hits	259	Shared Neighborhood Hits	27
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

CCD41_MOUSE
θ value	0.21417 (rank : 18)	NC score	0.060160 (rank : 31)
Query Neighborhood Hits	174	Target Neighborhood Hits	1399	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

MYST3_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.053836 (rank : 55)
Query Neighborhood Hits	174	Target Neighborhood Hits	772	Shared Neighborhood Hits	40
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

GOGB1_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.064604 (rank : 24)
Query Neighborhood Hits	174	Target Neighborhood Hits	2297	Shared Neighborhood Hits	78
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

RSF1_HUMAN
θ value	0.279714 (rank : 21)	NC score	0.086932 (rank : 8)
Query Neighborhood Hits	174	Target Neighborhood Hits	539	Shared Neighborhood Hits	50
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SYCP1_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.066102 (rank : 21)
Query Neighborhood Hits	174	Target Neighborhood Hits	1456	Shared Neighborhood Hits	65
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

BRCA2_HUMAN
θ value	0.365318 (rank : 23)	NC score	0.065908 (rank : 22)
Query Neighborhood Hits	174	Target Neighborhood Hits	202	Shared Neighborhood Hits	26
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

PININ_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.088153 (rank : 7)
Query Neighborhood Hits	174	Target Neighborhood Hits	753	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CE290_HUMAN
θ value	0.47712 (rank : 25)	NC score	0.064803 (rank : 23)
Query Neighborhood Hits	174	Target Neighborhood Hits	1553	Shared Neighborhood Hits	56
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

ANKK1_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.010753 (rank : 173)
Query Neighborhood Hits	174	Target Neighborhood Hits	1075	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

BRD4_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.055487 (rank : 44)
Query Neighborhood Hits	174	Target Neighborhood Hits	851	Shared Neighborhood Hits	42
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CHD1_HUMAN
θ value	0.62314 (rank : 28)	NC score	0.036381 (rank : 105)
Query Neighborhood Hits	174	Target Neighborhood Hits	337	Shared Neighborhood Hits	24
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

DSPP_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.070392 (rank : 13)
Query Neighborhood Hits	174	Target Neighborhood Hits	645	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

FYB_HUMAN
θ value	0.62314 (rank : 30)	NC score	0.057001 (rank : 41)
Query Neighborhood Hits	174	Target Neighborhood Hits	379	Shared Neighborhood Hits	25
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GOGA4_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.059683 (rank : 33)
Query Neighborhood Hits	174	Target Neighborhood Hits	2034	Shared Neighborhood Hits	69
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HMMR_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.060850 (rank : 28)
Query Neighborhood Hits	174	Target Neighborhood Hits	1082	Shared Neighborhood Hits	47
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MYCB2_HUMAN
θ value	0.62314 (rank : 33)	NC score	0.060120 (rank : 32)
Query Neighborhood Hits	174	Target Neighborhood Hits	390	Shared Neighborhood Hits	24
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PDE1C_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.038296 (rank : 98)
Query Neighborhood Hits	174	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

REST_MOUSE
θ value	0.62314 (rank : 35)	NC score	0.055485 (rank : 45)
Query Neighborhood Hits	174	Target Neighborhood Hits	1506	Shared Neighborhood Hits	65
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

TGON2_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.070336 (rank : 14)
Query Neighborhood Hits	174	Target Neighborhood Hits	1037	Shared Neighborhood Hits	52
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ATRX_MOUSE
θ value	0.813845 (rank : 37)	NC score	0.085427 (rank : 9)
Query Neighborhood Hits	174	Target Neighborhood Hits	682	Shared Neighborhood Hits	49
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BMPR2_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.017295 (rank : 155)
Query Neighborhood Hits	174	Target Neighborhood Hits	736	Shared Neighborhood Hits	7
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

MPP10_MOUSE
θ value	0.813845 (rank : 39)	NC score	0.060281 (rank : 29)
Query Neighborhood Hits	174	Target Neighborhood Hits	251	Shared Neighborhood Hits	18
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

OSBL6_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.037383 (rank : 103)
Query Neighborhood Hits	174	Target Neighborhood Hits	101	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

PININ_MOUSE
θ value	0.813845 (rank : 41)	NC score	0.082476 (rank : 10)
Query Neighborhood Hits	174	Target Neighborhood Hits	777	Shared Neighborhood Hits	49
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RASA2_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.035144 (rank : 107)
Query Neighborhood Hits	174	Target Neighborhood Hits	159	Shared Neighborhood Hits	4
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

TARA_HUMAN
θ value	0.813845 (rank : 43)	NC score	0.066123 (rank : 20)
Query Neighborhood Hits	174	Target Neighborhood Hits	1626	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

UBP32_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.034264 (rank : 109)
Query Neighborhood Hits	174	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

BCAS1_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.047984 (rank : 79)
Query Neighborhood Hits	174	Target Neighborhood Hits	215	Shared Neighborhood Hits	8
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

EPN4_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.052061 (rank : 66)
Query Neighborhood Hits	174	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q14677, Q8NAF1, Q96E05	Gene names	CLINT1, ENTH, EPN4, EPNR, KIAA0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin-interacting protein localized in the trans- Golgi region) (Clint).

EPN4_MOUSE
θ value	1.06291 (rank : 47)	NC score	0.051774 (rank : 67)
Query Neighborhood Hits	174	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KN9, Q8CFH4	Gene names	Clint1, Enth, Epn4, Epnr, Kiaa0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin).

RASA2_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.034248 (rank : 110)
Query Neighborhood Hits	174	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

BARD1_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.020365 (rank : 145)
Query Neighborhood Hits	174	Target Neighborhood Hits	411	Shared Neighborhood Hits	9
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CA103_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.053309 (rank : 60)
Query Neighborhood Hits	174	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T3J3, Q86XS4, Q8N3B6, Q96HT4, Q9NUM5, Q9NV32	Gene names	C1orf103, RIF1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf103 (Receptor-interacting factor 1).

CP135_MOUSE
θ value	1.38821 (rank : 51)	NC score	0.054492 (rank : 51)
Query Neighborhood Hits	174	Target Neighborhood Hits	1278	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

GCC2_MOUSE
θ value	1.38821 (rank : 52)	NC score	0.055148 (rank : 47)
Query Neighborhood Hits	174	Target Neighborhood Hits	1619	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

PRP4B_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.020104 (rank : 146)
Query Neighborhood Hits	174	Target Neighborhood Hits	1030	Shared Neighborhood Hits	31
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

UBP6_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.030473 (rank : 117)
Query Neighborhood Hits	174	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

ATF6A_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.041321 (rank : 92)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

BPA1_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.047706 (rank : 80)
Query Neighborhood Hits	174	Target Neighborhood Hits	1477	Shared Neighborhood Hits	60
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

C8AP2_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.081927 (rank : 11)
Query Neighborhood Hits	174	Target Neighborhood Hits	548	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

ERC2_MOUSE
θ value	1.81305 (rank : 58)	NC score	0.056056 (rank : 42)
Query Neighborhood Hits	174	Target Neighborhood Hits	1166	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ITB6_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.014374 (rank : 161)
Query Neighborhood Hits	174	Target Neighborhood Hits	318	Shared Neighborhood Hits	5
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

KLC3_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.027555 (rank : 126)
Query Neighborhood Hits	174	Target Neighborhood Hits	137	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P597, Q6GMU2, Q8NAL1, Q8WWJ9	Gene names	KLC3, KLC2, KLC2L
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3 (kinesin light chain 2) (KLC2-like).

MYCB2_MOUSE
θ value	1.81305 (rank : 61)	NC score	0.050601 (rank : 74)
Query Neighborhood Hits	174	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYH8_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.037384 (rank : 102)
Query Neighborhood Hits	174	Target Neighborhood Hits	1610	Shared Neighborhood Hits	59
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

OSBL6_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.035193 (rank : 106)
Query Neighborhood Hits	174	Target Neighborhood Hits	105	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

PPIG_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.053366 (rank : 59)
Query Neighborhood Hits	174	Target Neighborhood Hits	670	Shared Neighborhood Hits	66
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

THOC2_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.062713 (rank : 25)
Query Neighborhood Hits	174	Target Neighborhood Hits	337	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

ZFP37_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.003668 (rank : 187)
Query Neighborhood Hits	174	Target Neighborhood Hits	797	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6Q3	Gene names	ZFP37
Domain Architecture
Description	Zinc finger protein 37 homolog (Zfp-37).

ZN577_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.003519 (rank : 188)
Query Neighborhood Hits	174	Target Neighborhood Hits	748	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BSK1	Gene names	ZNF577
Domain Architecture	No domain graphic available
Description	Zinc finger protein 577.

ABTAP_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.057297 (rank : 40)
Query Neighborhood Hits	174	Target Neighborhood Hits	381	Shared Neighborhood Hits	31
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

AN30A_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.049141 (rank : 76)
Query Neighborhood Hits	174	Target Neighborhood Hits	1119	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CENPF_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.054238 (rank : 53)
Query Neighborhood Hits	174	Target Neighborhood Hits	1932	Shared Neighborhood Hits	65
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CF146_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.045944 (rank : 84)
Query Neighborhood Hits	174	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D9W6	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf146 homolog.

CIR_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.058179 (rank : 37)
Query Neighborhood Hits	174	Target Neighborhood Hits	255	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

CN145_MOUSE
θ value	2.36792 (rank : 73)	NC score	0.057908 (rank : 38)
Query Neighborhood Hits	174	Target Neighborhood Hits	916	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

ERC2_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.054550 (rank : 50)
Query Neighborhood Hits	174	Target Neighborhood Hits	1156	Shared Neighborhood Hits	51
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

MYST3_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.044316 (rank : 89)
Query Neighborhood Hits	174	Target Neighborhood Hits	688	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NKTR_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.040819 (rank : 93)
Query Neighborhood Hits	174	Target Neighborhood Hits	417	Shared Neighborhood Hits	38
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

SFRIP_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.068311 (rank : 15)
Query Neighborhood Hits	174	Target Neighborhood Hits	530	Shared Neighborhood Hits	41
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SPB10_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.011845 (rank : 170)
Query Neighborhood Hits	174	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P48595, Q4VAX4	Gene names	SERPINB10, PI10
Domain Architecture
Description	Serpin B10 (Bomapin) (Protease inhibitor 10).

TOPRS_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.033951 (rank : 111)
Query Neighborhood Hits	174	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

ZBTB6_MOUSE
θ value	2.36792 (rank : 80)	NC score	0.009150 (rank : 176)
Query Neighborhood Hits	174	Target Neighborhood Hits	793	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K088, Q8BLM4	Gene names	Zbtb6, Zfp482, Znf482
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482).

BMPR2_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.014654 (rank : 160)
Query Neighborhood Hits	174	Target Neighborhood Hits	738	Shared Neighborhood Hits	8
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

CLSPN_HUMAN
θ value	3.0926 (rank : 82)	NC score	0.046205 (rank : 81)
Query Neighborhood Hits	174	Target Neighborhood Hits	433	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

JIP4_MOUSE
θ value	3.0926 (rank : 83)	NC score	0.038564 (rank : 96)
Query Neighborhood Hits	174	Target Neighborhood Hits	593	Shared Neighborhood Hits	38
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

K22E_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.019548 (rank : 147)
Query Neighborhood Hits	174	Target Neighborhood Hits	515	Shared Neighborhood Hits	25
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

PLCD1_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.037782 (rank : 100)
Query Neighborhood Hits	174	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

TSH2_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.030819 (rank : 116)
Query Neighborhood Hits	174	Target Neighborhood Hits	479	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

AATM_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.023862 (rank : 136)
Query Neighborhood Hits	174	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P05202, O09188	Gene names	Got2, Got-2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

BNIP3_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.032570 (rank : 113)
Query Neighborhood Hits	174	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q12983, O14620, Q96GP0	Gene names	BNIP3, NIP3
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.

BRCA1_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.024910 (rank : 132)
Query Neighborhood Hits	174	Target Neighborhood Hits	381	Shared Neighborhood Hits	14
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

C8AP2_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.059454 (rank : 34)
Query Neighborhood Hits	174	Target Neighborhood Hits	405	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

DMD_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.046144 (rank : 82)
Query Neighborhood Hits	174	Target Neighborhood Hits	1135	Shared Neighborhood Hits	43
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

EPIPL_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.021823 (rank : 139)
Query Neighborhood Hits	174	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	P58107, Q76E58	Gene names	EPPK1, EPIPL
Domain Architecture
Description	Epiplakin (450 kDa epidermal antigen).

HCDH_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.025843 (rank : 129)
Query Neighborhood Hits	174	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q61425, Q3TF75, Q3THK8, Q3UFI0, Q8K149, Q925U9	Gene names	Hadhsc, Hadh, Mschad, Schad
Domain Architecture
Description	Short chain 3-hydroxyacyl-CoA dehydrogenase, mitochondrial precursor (EC 1.1.1.35) (HCDH) (Medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase).

IF4B_MOUSE
θ value	4.03905 (rank : 94)	NC score	0.028076 (rank : 125)
Query Neighborhood Hits	174	Target Neighborhood Hits	368	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MASTL_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.006198 (rank : 184)
Query Neighborhood Hits	174	Target Neighborhood Hits	862	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MDN1_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.053787 (rank : 56)
Query Neighborhood Hits	174	Target Neighborhood Hits	662	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

MUC1_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.029996 (rank : 120)
Query Neighborhood Hits	174	Target Neighborhood Hits	388	Shared Neighborhood Hits	13
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PMS1_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.029374 (rank : 121)
Query Neighborhood Hits	174	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

ROR1_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.003105 (rank : 189)
Query Neighborhood Hits	174	Target Neighborhood Hits	1018	Shared Neighborhood Hits	9
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

RSSA_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.044861 (rank : 87)
Query Neighborhood Hits	174	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	P08865, P11085, P12030, Q16471, Q6IPD1	Gene names	RPSA, LAMBR, LAMR1
Domain Architecture
Description	40S ribosomal protein SA (p40) (34/67 kDa laminin receptor) (Colon carcinoma laminin-binding protein) (NEM/1CHD4) (Multidrug resistance- associated protein MGr1-Ag).

RSSA_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.044873 (rank : 86)
Query Neighborhood Hits	174	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	P14206	Gene names	Rpsa, Lamr1, P40-8
Domain Architecture
Description	40S ribosomal protein SA (p40) (34/67 kDa laminin receptor).

SON_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.030179 (rank : 119)
Query Neighborhood Hits	174	Target Neighborhood Hits	957	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SP3_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.007282 (rank : 180)
Query Neighborhood Hits	174	Target Neighborhood Hits	737	Shared Neighborhood Hits	13
SwissProt Accessions	Q02447, Q8TD56, Q9BQR1	Gene names	SP3
Domain Architecture
Description	Transcription factor Sp3 (SPR-2).

ZBTB6_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.008036 (rank : 178)
Query Neighborhood Hits	174	Target Neighborhood Hits	805	Shared Neighborhood Hits	14
SwissProt Accessions	Q15916	Gene names	ZBTB6, ZID, ZNF482
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482) (Zinc finger protein with interaction domain).

ZN700_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.002446 (rank : 190)
Query Neighborhood Hits	174	Target Neighborhood Hits	772	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0M5	Gene names	ZNF700
Domain Architecture	No domain graphic available
Description	Zinc finger protein 700.

CT043_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.029228 (rank : 122)
Query Neighborhood Hits	174	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q99K95, Q543D3, Q80X88, Q9CV27	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf43 homolog.

CUZD1_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.012053 (rank : 169)
Query Neighborhood Hits	174	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

INADL_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.010989 (rank : 172)
Query Neighborhood Hits	174	Target Neighborhood Hits	290	Shared Neighborhood Hits	8
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

LAMA1_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.017550 (rank : 151)
Query Neighborhood Hits	174	Target Neighborhood Hits	838	Shared Neighborhood Hits	27
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MAP1B_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.055929 (rank : 43)
Query Neighborhood Hits	174	Target Neighborhood Hits	977	Shared Neighborhood Hits	59
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAP9_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.054354 (rank : 52)
Query Neighborhood Hits	174	Target Neighborhood Hits	529	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

NCOA6_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.026382 (rank : 128)
Query Neighborhood Hits	174	Target Neighborhood Hits	1202	Shared Neighborhood Hits	33
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NSD1_MOUSE
θ value	5.27518 (rank : 113)	NC score	0.032228 (rank : 114)
Query Neighborhood Hits	174	Target Neighborhood Hits	472	Shared Neighborhood Hits	25
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

P80C_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.037498 (rank : 101)
Query Neighborhood Hits	174	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

PALB2_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.031271 (rank : 115)
Query Neighborhood Hits	174	Target Neighborhood Hits	117	Shared Neighborhood Hits	12
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

RIF1_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.039603 (rank : 94)
Query Neighborhood Hits	174	Target Neighborhood Hits	315	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

SETD2_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.027062 (rank : 127)
Query Neighborhood Hits	174	Target Neighborhood Hits	412	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SFRP2_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.016916 (rank : 157)
Query Neighborhood Hits	174	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SPB10_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.009575 (rank : 175)
Query Neighborhood Hits	174	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1K6	Gene names	Serpinb10
Domain Architecture	No domain graphic available
Description	Serpin B10.

TARA_MOUSE
θ value	5.27518 (rank : 120)	NC score	0.054617 (rank : 49)
Query Neighborhood Hits	174	Target Neighborhood Hits	1133	Shared Neighborhood Hits	48
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCF8_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.008035 (rank : 179)
Query Neighborhood Hits	174	Target Neighborhood Hits	1057	Shared Neighborhood Hits	30
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

TSH2_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.024479 (rank : 134)
Query Neighborhood Hits	174	Target Neighborhood Hits	467	Shared Neighborhood Hits	10
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

TXND2_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.046072 (rank : 83)
Query Neighborhood Hits	174	Target Neighborhood Hits	793	Shared Neighborhood Hits	41
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

ANR26_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.049865 (rank : 75)
Query Neighborhood Hits	174	Target Neighborhood Hits	1614	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BUB1_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.018143 (rank : 149)
Query Neighborhood Hits	174	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

CAPS2_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.016256 (rank : 158)
Query Neighborhood Hits	174	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

CN145_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.051681 (rank : 68)
Query Neighborhood Hits	174	Target Neighborhood Hits	1196	Shared Neighborhood Hits	49
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

DVL1_MOUSE
θ value	6.88961 (rank : 128)	NC score	0.018723 (rank : 148)
Query Neighborhood Hits	174	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

FKSG2_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.022342 (rank : 138)
Query Neighborhood Hits	174	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HAU6	Gene names	FKSG2
Domain Architecture
Description	Apoptosis inhibitor FKSG2.

GPTC8_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.038255 (rank : 99)
Query Neighborhood Hits	174	Target Neighborhood Hits	366	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

HSP7C_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.013817 (rank : 164)
Query Neighborhood Hits	174	Target Neighborhood Hits	150	Shared Neighborhood Hits	19
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.014099 (rank : 163)
Query Neighborhood Hits	174	Target Neighborhood Hits	166	Shared Neighborhood Hits	20
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

I15RA_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.028260 (rank : 124)
Query Neighborhood Hits	174	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q13261, Q6B0J2, Q7LDR4, Q7Z609	Gene names	IL15RA
Domain Architecture	No domain graphic available
Description	Interleukin-15 receptor alpha chain precursor (IL-15R-alpha) (IL- 15RA).

IMB1_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.017466 (rank : 153)
Query Neighborhood Hits	174	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

INOC1_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.030300 (rank : 118)
Query Neighborhood Hits	174	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

MYH9_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.038396 (rank : 97)
Query Neighborhood Hits	174	Target Neighborhood Hits	1829	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NOL8_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.023551 (rank : 137)
Query Neighborhood Hits	174	Target Neighborhood Hits	210	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

NUCKS_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.035133 (rank : 108)
Query Neighborhood Hits	174	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

POLI_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.017138 (rank : 156)
Query Neighborhood Hits	174	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

RPB6_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.041967 (rank : 91)
Query Neighborhood Hits	174	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	P61218, P41584	Gene names	POLR2F, POLRF
Domain Architecture
Description	DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide (EC 2.7.7.6) (RPB6) (RPABC14.4) (RPB14.4) (RPABC2).

RPB6_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.041981 (rank : 90)
Query Neighborhood Hits	174	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	P61219	Gene names	Polr2f
Domain Architecture
Description	DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide (EC 2.7.7.6) (RPB6) (RPABC14.4) (RPB14.4).

SFRP2_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.015589 (rank : 159)
Query Neighborhood Hits	174	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

SGOL2_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.049070 (rank : 77)
Query Neighborhood Hits	174	Target Neighborhood Hits	207	Shared Neighborhood Hits	23
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

SH24A_MOUSE
θ value	6.88961 (rank : 144)	NC score	0.033419 (rank : 112)
Query Neighborhood Hits	174	Target Neighborhood Hits	326	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

SP3_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.006341 (rank : 183)
Query Neighborhood Hits	174	Target Neighborhood Hits	731	Shared Neighborhood Hits	13
SwissProt Accessions	O70494, Q68FF2, Q8CF64, Q8K378	Gene names	Sp3
Domain Architecture	No domain graphic available
Description	Transcription factor Sp3.

STC2_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.020707 (rank : 144)
Query Neighborhood Hits	174	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	O76061	Gene names	STC2
Domain Architecture
Description	Stanniocalcin-2 precursor (STC-2) (Stanniocalcin-related protein) (STCRP) (STC-related protein).

SYTL2_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.013534 (rank : 165)
Query Neighborhood Hits	174	Target Neighborhood Hits	248	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

UBP2L_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.025157 (rank : 131)
Query Neighborhood Hits	174	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

ZN638_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.037342 (rank : 104)
Query Neighborhood Hits	174	Target Neighborhood Hits	343	Shared Neighborhood Hits	33
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

ABLM1_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.005116 (rank : 185)
Query Neighborhood Hits	174	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

ANC1_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.021525 (rank : 141)
Query Neighborhood Hits	174	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

ANC1_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.021697 (rank : 140)
Query Neighborhood Hits	174	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

ANK2_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.020845 (rank : 143)
Query Neighborhood Hits	174	Target Neighborhood Hits	1615	Shared Neighborhood Hits	61
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASPM_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.044413 (rank : 88)
Query Neighborhood Hits	174	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

BTBD7_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.013205 (rank : 167)
Query Neighborhood Hits	174	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

CA026_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.025316 (rank : 130)
Query Neighborhood Hits	174	Target Neighborhood Hits	100	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

CCNB3_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.017536 (rank : 152)
Query Neighborhood Hits	174	Target Neighborhood Hits	211	Shared Neighborhood Hits	19
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CHD9_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.029081 (rank : 123)
Query Neighborhood Hits	174	Target Neighborhood Hits	427	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

DVL1L_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.017620 (rank : 150)
Query Neighborhood Hits	174	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

DVL1_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.017324 (rank : 154)
Query Neighborhood Hits	174	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

FOXF1_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.007204 (rank : 182)
Query Neighborhood Hits	174	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q12946, Q5FWE5	Gene names	FOXF1, FKHL5, FREAC1
Domain Architecture
Description	Forkhead box protein F1 (Forkhead-related protein FKHL5) (Forkhead- related transcription factor 1) (FREAC-1) (Forkhead-related activator 1).

FOXF1_MOUSE
θ value	8.99809 (rank : 162)	NC score	0.007241 (rank : 181)
Query Neighborhood Hits	174	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q61080, Q61661	Gene names	Foxf1, Fkhl5, Foxf1a, Freac1, Hfh8
Domain Architecture
Description	Forkhead box protein F1 (Forkhead-related protein FKHL5) (Forkhead- related transcription factor 1) (FREAC-1) (Hepatocyte nuclear factor 3 forkhead homolog 8) (HFH-8).

FUS_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.013348 (rank : 166)
Query Neighborhood Hits	174	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

GSTM2_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.008337 (rank : 177)
Query Neighborhood Hits	174	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P15626	Gene names	Gstm2
Domain Architecture
Description	Glutathione S-transferase Mu 2 (EC 2.5.1.18) (GST class-mu 2) (Glutathione S-transferase pmGT2) (GST 5-5).

ITF2_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.013073 (rank : 168)
Query Neighborhood Hits	174	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

NCOA3_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.038658 (rank : 95)
Query Neighborhood Hits	174	Target Neighborhood Hits	203	Shared Neighborhood Hits	12
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NPT1_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.011079 (rank : 171)
Query Neighborhood Hits	174	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q14916, Q13783	Gene names	SLC17A1, NPT1
Domain Architecture
Description	Sodium-dependent phosphate transport protein 1 (Sodium/phosphate cotransporter 1) (Na(+)/PI cotransporter 1) (Solute carrier family 17 member 1) (Renal sodium-dependent phosphate transport protein 1) (Renal sodium-phosphate transport protein 1) (Renal Na(+)-dependent phosphate cotransporter 1) (Na/Pi-4).

RAB3I_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.024762 (rank : 133)
Query Neighborhood Hits	174	Target Neighborhood Hits	270	Shared Neighborhood Hits	16
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

RNS10_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.021196 (rank : 142)
Query Neighborhood Hits	174	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D5A9, Q6XL64	Gene names	Rnase10
Domain Architecture	No domain graphic available
Description	Ribonuclease-like protein 10 precursor (Protein Train A).

RPGR1_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.048265 (rank : 78)
Query Neighborhood Hits	174	Target Neighborhood Hits	578	Shared Neighborhood Hits	36
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SHAN2_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.014249 (rank : 162)
Query Neighborhood Hits	174	Target Neighborhood Hits	346	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

TPR_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.052991 (rank : 61)
Query Neighborhood Hits	174	Target Neighborhood Hits	1921	Shared Neighborhood Hits	69
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TRIO_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.010317 (rank : 174)
Query Neighborhood Hits	174	Target Neighborhood Hits	1580	Shared Neighborhood Hits	38
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

VLDLR_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.003962 (rank : 186)
Query Neighborhood Hits	174	Target Neighborhood Hits	383	Shared Neighborhood Hits	5
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

CCD41_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.051031 (rank : 72)
Query Neighborhood Hits	174	Target Neighborhood Hits	1139	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CF060_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.050937 (rank : 73)
Query Neighborhood Hits	174	Target Neighborhood Hits	1270	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

DMP1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.052322 (rank : 64)
Query Neighborhood Hits	174	Target Neighborhood Hits	491	Shared Neighborhood Hits	44
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

ESCO1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.058918 (rank : 36)
Query Neighborhood Hits	174	Target Neighborhood Hits	361	Shared Neighborhood Hits	41
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

GOGA4_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.053623 (rank : 57)
Query Neighborhood Hits	174	Target Neighborhood Hits	1939	Shared Neighborhood Hits	65
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

IWS1_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.051124 (rank : 71)
Query Neighborhood Hits	174	Target Neighborhood Hits	1241	Shared Neighborhood Hits	63
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LRRF1_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.054936 (rank : 48)
Query Neighborhood Hits	174	Target Neighborhood Hits	440	Shared Neighborhood Hits	34
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

MAP9_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.053419 (rank : 58)
Query Neighborhood Hits	174	Target Neighborhood Hits	518	Shared Neighborhood Hits	46
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

NIPBL_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.057667 (rank : 39)
Query Neighborhood Hits	174	Target Neighborhood Hits	1311	Shared Neighborhood Hits	76
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.054185 (rank : 54)
Query Neighborhood Hits	174	Target Neighborhood Hits	1041	Shared Neighborhood Hits	61
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RBBP6_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.062263 (rank : 26)
Query Neighborhood Hits	174	Target Neighborhood Hits	1135	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

REST_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.051677 (rank : 69)
Query Neighborhood Hits	174	Target Neighborhood Hits	1605	Shared Neighborhood Hits	69
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RRBP1_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.052698 (rank : 63)
Query Neighborhood Hits	174	Target Neighborhood Hits	1650	Shared Neighborhood Hits	67
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SYCP1_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.052910 (rank : 62)
Query Neighborhood Hits	174	Target Neighborhood Hits	1313	Shared Neighborhood Hits	54
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TRIPB_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.052220 (rank : 65)
Query Neighborhood Hits	174	Target Neighborhood Hits	1587	Shared Neighborhood Hits	65
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TXND2_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.055389 (rank : 46)
Query Neighborhood Hits	174	Target Neighborhood Hits	828	Shared Neighborhood Hits	52
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

Hits sorted by NC score

TEX15_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	174
SwissProt Accessions	Q9BXT5	Gene names	TEX15
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 15 protein.

CYLC1_HUMAN
NC score	0.126342 (rank : 2)	θ value	0.0193708 (rank : 5)
Query Neighborhood Hits	174	Target Neighborhood Hits	408	Shared Neighborhood Hits	46
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

AF9_HUMAN
NC score	0.126025 (rank : 3)	θ value	0.00390308 (rank : 3)
Query Neighborhood Hits	174	Target Neighborhood Hits	202	Shared Neighborhood Hits	17
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

ATRX_HUMAN
NC score	0.113856 (rank : 4)	θ value	0.000461057 (rank : 2)
Query Neighborhood Hits	174	Target Neighborhood Hits	842	Shared Neighborhood Hits	63
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

CI084_HUMAN
NC score	0.101737 (rank : 5)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	174	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VXU9, Q96M73	Gene names	C9orf84
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf84.

LRRF1_HUMAN
NC score	0.100966 (rank : 6)	θ value	0.0193708 (rank : 6)
Query Neighborhood Hits	174	Target Neighborhood Hits	625	Shared Neighborhood Hits	42
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

PININ_HUMAN
NC score	0.088153 (rank : 7)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	174	Target Neighborhood Hits	753	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

RSF1_HUMAN
NC score	0.086932 (rank : 8)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	174	Target Neighborhood Hits	539	Shared Neighborhood Hits	50
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

ATRX_MOUSE
NC score	0.085427 (rank : 9)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	174	Target Neighborhood Hits	682	Shared Neighborhood Hits	49
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

PININ_MOUSE
NC score	0.082476 (rank : 10)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	174	Target Neighborhood Hits	777	Shared Neighborhood Hits	49
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

C8AP2_HUMAN
NC score	0.081927 (rank : 11)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	174	Target Neighborhood Hits	548	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

PIBF1_HUMAN
NC score	0.071161 (rank : 12)	θ value	0.0148317 (rank : 4)
Query Neighborhood Hits	174	Target Neighborhood Hits	1041	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

DSPP_HUMAN
NC score	0.070392 (rank : 13)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	174	Target Neighborhood Hits	645	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TGON2_HUMAN
NC score	0.070336 (rank : 14)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	174	Target Neighborhood Hits	1037	Shared Neighborhood Hits	52
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SFRIP_HUMAN
NC score	0.068311 (rank : 15)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	174	Target Neighborhood Hits	530	Shared Neighborhood Hits	41
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

ESCO1_MOUSE
NC score	0.068170 (rank : 16)	θ value	0.125558 (rank : 13)
Query Neighborhood Hits	174	Target Neighborhood Hits	87	Shared Neighborhood Hits	13
SwissProt Accessions	Q69Z69, Q8BQI2, Q8BR47, Q922F5	Gene names	Esco1, Kiaa1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1).

UBP1_HUMAN
NC score	0.067934 (rank : 17)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	174	Target Neighborhood Hits	259	Shared Neighborhood Hits	27
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

SYNE2_HUMAN
NC score	0.067784 (rank : 18)	θ value	0.125558 (rank : 14)
Query Neighborhood Hits	174	Target Neighborhood Hits	1323	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

ASPM_MOUSE
NC score	0.066273 (rank : 19)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	174	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

TARA_HUMAN
NC score	0.066123 (rank : 20)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	174	Target Neighborhood Hits	1626	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SYCP1_MOUSE
NC score	0.066102 (rank : 21)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	174	Target Neighborhood Hits	1456	Shared Neighborhood Hits	65
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

BRCA2_HUMAN
NC score	0.065908 (rank : 22)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	174	Target Neighborhood Hits	202	Shared Neighborhood Hits	26
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

CE290_HUMAN
NC score	0.064803 (rank : 23)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	174	Target Neighborhood Hits	1553	Shared Neighborhood Hits	56
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

GOGB1_HUMAN
NC score	0.064604 (rank : 24)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	174	Target Neighborhood Hits	2297	Shared Neighborhood Hits	78
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

THOC2_HUMAN
NC score	0.062713 (rank : 25)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	174	Target Neighborhood Hits	337	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

RBBP6_HUMAN
NC score	0.062263 (rank : 26)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	174	Target Neighborhood Hits	1135	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

BRD4_MOUSE
NC score	0.060915 (rank : 27)	θ value	0.0563607 (rank : 9)
Query Neighborhood Hits	174	Target Neighborhood Hits	845	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

HMMR_HUMAN
NC score	0.060850 (rank : 28)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	174	Target Neighborhood Hits	1082	Shared Neighborhood Hits	47
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

MPP10_MOUSE
NC score	0.060281 (rank : 29)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	174	Target Neighborhood Hits	251	Shared Neighborhood Hits	18
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

CENPE_HUMAN
NC score	0.060247 (rank : 30)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	174	Target Neighborhood Hits	2060	Shared Neighborhood Hits	75
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CCD41_MOUSE
NC score	0.060160 (rank : 31)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	174	Target Neighborhood Hits	1399	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

MYCB2_HUMAN
NC score	0.060120 (rank : 32)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	174	Target Neighborhood Hits	390	Shared Neighborhood Hits	24
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

GOGA4_HUMAN
NC score	0.059683 (rank : 33)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	174	Target Neighborhood Hits	2034	Shared Neighborhood Hits	69
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

C8AP2_MOUSE
NC score	0.059454 (rank : 34)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	174	Target Neighborhood Hits	405	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

NCOA3_HUMAN
NC score	0.059380 (rank : 35)	θ value	0.0193708 (rank : 7)
Query Neighborhood Hits	174	Target Neighborhood Hits	171	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

ESCO1_HUMAN
NC score	0.058918 (rank : 36)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	174	Target Neighborhood Hits	361	Shared Neighborhood Hits	41
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

CIR_MOUSE
NC score	0.058179 (rank : 37)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	174	Target Neighborhood Hits	255	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

CN145_MOUSE
NC score	0.057908 (rank : 38)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	174	Target Neighborhood Hits	916	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

NIPBL_HUMAN
NC score	0.057667 (rank : 39)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	174	Target Neighborhood Hits	1311	Shared Neighborhood Hits	76
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ABTAP_MOUSE
NC score	0.057297 (rank : 40)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	174	Target Neighborhood Hits	381	Shared Neighborhood Hits	31
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

FYB_HUMAN
NC score	0.057001 (rank : 41)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	174	Target Neighborhood Hits	379	Shared Neighborhood Hits	25
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

ERC2_MOUSE
NC score	0.056056 (rank : 42)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	174	Target Neighborhood Hits	1166	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

MAP1B_MOUSE
NC score	0.055929 (rank : 43)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	174	Target Neighborhood Hits	977	Shared Neighborhood Hits	59
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

BRD4_HUMAN
NC score	0.055487 (rank : 44)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	174	Target Neighborhood Hits	851	Shared Neighborhood Hits	42
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

REST_MOUSE
NC score	0.055485 (rank : 45)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	174	Target Neighborhood Hits	1506	Shared Neighborhood Hits	65
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

TXND2_MOUSE
NC score	0.055389 (rank : 46)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	174	Target Neighborhood Hits	828	Shared Neighborhood Hits	52
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

GCC2_MOUSE
NC score	0.055148 (rank : 47)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	174	Target Neighborhood Hits	1619	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

LRRF1_MOUSE
NC score	0.054936 (rank : 48)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	174	Target Neighborhood Hits	440	Shared Neighborhood Hits	34
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

TARA_MOUSE
NC score	0.054617 (rank : 49)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	174	Target Neighborhood Hits	1133	Shared Neighborhood Hits	48
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ERC2_HUMAN
NC score	0.054550 (rank : 50)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	174	Target Neighborhood Hits	1156	Shared Neighborhood Hits	51
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

CP135_MOUSE
NC score	0.054492 (rank : 51)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	174	Target Neighborhood Hits	1278	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MAP9_MOUSE
NC score	0.054354 (rank : 52)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	174	Target Neighborhood Hits	529	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

CENPF_HUMAN
NC score	0.054238 (rank : 53)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	174	Target Neighborhood Hits	1932	Shared Neighborhood Hits	65
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

NPBL_MOUSE
NC score	0.054185 (rank : 54)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	174	Target Neighborhood Hits	1041	Shared Neighborhood Hits	61
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

MYST3_HUMAN
NC score	0.053836 (rank : 55)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	174	Target Neighborhood Hits	772	Shared Neighborhood Hits	40
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MDN1_HUMAN
NC score	0.053787 (rank : 56)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	174	Target Neighborhood Hits	662	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

GOGA4_MOUSE
NC score	0.053623 (rank : 57)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	174	Target Neighborhood Hits	1939	Shared Neighborhood Hits	65
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MAP9_HUMAN
NC score	0.053419 (rank : 58)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	174	Target Neighborhood Hits	518	Shared Neighborhood Hits	46
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

PPIG_HUMAN
NC score	0.053366 (rank : 59)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	174	Target Neighborhood Hits	670	Shared Neighborhood Hits	66
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

CA103_HUMAN
NC score	0.053309 (rank : 60)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	174	Target Neighborhood Hits	82	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T3J3, Q86XS4, Q8N3B6, Q96HT4, Q9NUM5, Q9NV32	Gene names	C1orf103, RIF1
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf103 (Receptor-interacting factor 1).

TPR_HUMAN
NC score	0.052991 (rank : 61)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	174	Target Neighborhood Hits	1921	Shared Neighborhood Hits	69
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SYCP1_HUMAN
NC score	0.052910 (rank : 62)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	174	Target Neighborhood Hits	1313	Shared Neighborhood Hits	54
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

RRBP1_MOUSE
NC score	0.052698 (rank : 63)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	174	Target Neighborhood Hits	1650	Shared Neighborhood Hits	67
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

DMP1_HUMAN
NC score	0.052322 (rank : 64)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	174	Target Neighborhood Hits	491	Shared Neighborhood Hits	44
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

TRIPB_HUMAN
NC score	0.052220 (rank : 65)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	174	Target Neighborhood Hits	1587	Shared Neighborhood Hits	65
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

EPN4_HUMAN
NC score	0.052061 (rank : 66)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	174	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q14677, Q8NAF1, Q96E05	Gene names	CLINT1, ENTH, EPN4, EPNR, KIAA0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin-interacting protein localized in the trans- Golgi region) (Clint).

EPN4_MOUSE
NC score	0.051774 (rank : 67)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	174	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q99KN9, Q8CFH4	Gene names	Clint1, Enth, Epn4, Epnr, Kiaa0171
Domain Architecture
Description	Clathrin interactor 1 (Epsin-4) (Epsin-related protein) (EpsinR) (Enthoprotin).

CN145_HUMAN
NC score	0.051681 (rank : 68)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	174	Target Neighborhood Hits	1196	Shared Neighborhood Hits	49
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

REST_HUMAN
NC score	0.051677 (rank : 69)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	174	Target Neighborhood Hits	1605	Shared Neighborhood Hits	69
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

PLCD1_MOUSE
NC score	0.051570 (rank : 70)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	174	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

IWS1_HUMAN
NC score	0.051124 (rank : 71)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	174	Target Neighborhood Hits	1241	Shared Neighborhood Hits	63
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CCD41_HUMAN
NC score	0.051031 (rank : 72)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	174	Target Neighborhood Hits	1139	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CF060_HUMAN
NC score	0.050937 (rank : 73)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	174	Target Neighborhood Hits	1270	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

MYCB2_MOUSE
NC score	0.050601 (rank : 74)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	174	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ANR26_HUMAN
NC score	0.049865 (rank : 75)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	174	Target Neighborhood Hits	1614	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AN30A_HUMAN
NC score	0.049141 (rank : 76)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	174	Target Neighborhood Hits	1119	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

SGOL2_HUMAN
NC score	0.049070 (rank : 77)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	174	Target Neighborhood Hits	207	Shared Neighborhood Hits	23
SwissProt Accessions	Q562F6, Q53RR9, Q53T20, Q86XY4, Q8IWK2, Q8IZK1, Q8N1Q5, Q96LQ3	Gene names	SGOL2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2 (Tripin).

RPGR1_HUMAN
NC score	0.048265 (rank : 78)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	174	Target Neighborhood Hits	578	Shared Neighborhood Hits	36
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

BCAS1_MOUSE
NC score	0.047984 (rank : 79)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	174	Target Neighborhood Hits	215	Shared Neighborhood Hits	8
SwissProt Accessions	Q80YN3, Q9CVA1	Gene names	Bcas1, Nabc1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog).

BPA1_MOUSE
NC score	0.047706 (rank : 80)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	174	Target Neighborhood Hits	1477	Shared Neighborhood Hits	60
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CLSPN_HUMAN
NC score	0.046205 (rank : 81)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	174	Target Neighborhood Hits	433	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

DMD_HUMAN
NC score	0.046144 (rank : 82)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	174	Target Neighborhood Hits	1135	Shared Neighborhood Hits	43
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

TXND2_HUMAN
NC score	0.046072 (rank : 83)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	174	Target Neighborhood Hits	793	Shared Neighborhood Hits	41
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CF146_MOUSE
NC score	0.045944 (rank : 84)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	174	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D9W6	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf146 homolog.

PDE1C_HUMAN
NC score	0.045678 (rank : 85)	θ value	0.0736092 (rank : 11)
Query Neighborhood Hits	174	Target Neighborhood Hits	134	Shared Neighborhood Hits	12
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).

RSSA_MOUSE
NC score	0.044873 (rank : 86)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	174	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	P14206	Gene names	Rpsa, Lamr1, P40-8
Domain Architecture
Description	40S ribosomal protein SA (p40) (34/67 kDa laminin receptor).

RSSA_HUMAN
NC score	0.044861 (rank : 87)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	174	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	P08865, P11085, P12030, Q16471, Q6IPD1	Gene names	RPSA, LAMBR, LAMR1
Domain Architecture
Description	40S ribosomal protein SA (p40) (34/67 kDa laminin receptor) (Colon carcinoma laminin-binding protein) (NEM/1CHD4) (Multidrug resistance- associated protein MGr1-Ag).

ASPM_HUMAN
NC score	0.044413 (rank : 88)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	174	Target Neighborhood Hits	197	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

MYST3_MOUSE
NC score	0.044316 (rank : 89)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	174	Target Neighborhood Hits	688	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

RPB6_MOUSE
NC score	0.041981 (rank : 90)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	174	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	P61219	Gene names	Polr2f
Domain Architecture
Description	DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide (EC 2.7.7.6) (RPB6) (RPABC14.4) (RPB14.4).

RPB6_HUMAN
NC score	0.041967 (rank : 91)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	174	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	P61218, P41584	Gene names	POLR2F, POLRF
Domain Architecture
Description	DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide (EC 2.7.7.6) (RPB6) (RPABC14.4) (RPB14.4) (RPABC2).

ATF6A_HUMAN
NC score	0.041321 (rank : 92)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	174	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	P18850, O15139, Q5VW62, Q6IPB5, Q9UEC9	Gene names	ATF6
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 alpha (Activating transcription factor 6 alpha) (ATF6-alpha).

NKTR_MOUSE
NC score	0.040819 (rank : 93)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	174	Target Neighborhood Hits	417	Shared Neighborhood Hits	38
SwissProt Accessions	P30415	Gene names	Nktr
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RIF1_MOUSE
NC score	0.039603 (rank : 94)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	174	Target Neighborhood Hits	315	Shared Neighborhood Hits	30
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

NCOA3_MOUSE
NC score	0.038658 (rank : 95)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	174	Target Neighborhood Hits	203	Shared Neighborhood Hits	12
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

JIP4_MOUSE
NC score	0.038564 (rank : 96)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	174	Target Neighborhood Hits	593	Shared Neighborhood Hits	38
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

MYH9_MOUSE
NC score	0.038396 (rank : 97)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	174	Target Neighborhood Hits	1829	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PDE1C_MOUSE
NC score	0.038296 (rank : 98)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	174	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

GPTC8_HUMAN
NC score	0.038255 (rank : 99)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	174	Target Neighborhood Hits	366	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

PLCD1_HUMAN
NC score	0.037782 (rank : 100)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	174	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

P80C_HUMAN
NC score	0.037498 (rank : 101)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	174	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

MYH8_HUMAN
NC score	0.037384 (rank : 102)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	174	Target Neighborhood Hits	1610	Shared Neighborhood Hits	59
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

OSBL6_HUMAN
NC score	0.037383 (rank : 103)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	174	Target Neighborhood Hits	101	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

ZN638_HUMAN
NC score	0.037342 (rank : 104)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	174	Target Neighborhood Hits	343	Shared Neighborhood Hits	33
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

CHD1_HUMAN
NC score	0.036381 (rank : 105)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	174	Target Neighborhood Hits	337	Shared Neighborhood Hits	24
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

OSBL6_MOUSE
NC score	0.035193 (rank : 106)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	174	Target Neighborhood Hits	105	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

RASA2_MOUSE
NC score	0.035144 (rank : 107)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	174	Target Neighborhood Hits	159	Shared Neighborhood Hits	4
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

NUCKS_MOUSE
NC score	0.035133 (rank : 108)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	174	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

UBP32_HUMAN
NC score	0.034264 (rank : 109)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	174	Target Neighborhood Hits	170	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

RASA2_HUMAN
NC score	0.034248 (rank : 110)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	174	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

TOPRS_HUMAN
NC score	0.033951 (rank : 111)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	174	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

SH24A_MOUSE
NC score	0.033419 (rank : 112)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	174	Target Neighborhood Hits	326	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

BNIP3_HUMAN
NC score	0.032570 (rank : 113)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	174	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q12983, O14620, Q96GP0	Gene names	BNIP3, NIP3
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.

NSD1_MOUSE
NC score	0.032228 (rank : 114)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	174	Target Neighborhood Hits	472	Shared Neighborhood Hits	25
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PALB2_HUMAN
NC score	0.031271 (rank : 115)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	174	Target Neighborhood Hits	117	Shared Neighborhood Hits	12
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

TSH2_HUMAN
NC score	0.030819 (rank : 116)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	174	Target Neighborhood Hits	479	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRE2, Q4VXM4, Q6N003, Q8N260	Gene names	TSHZ2, C20orf17, TSH2, ZNF218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (Ovarian cancer-related protein 10-2) (OVC10-2).

UBP6_HUMAN
NC score	0.030473 (rank : 117)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	174	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

INOC1_HUMAN
NC score	0.030300 (rank : 118)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	174	Target Neighborhood Hits	181	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

SON_MOUSE
NC score	0.030179 (rank : 119)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	174	Target Neighborhood Hits	957	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MUC1_MOUSE
NC score	0.029996 (rank : 120)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	174	Target Neighborhood Hits	388	Shared Neighborhood Hits	13
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PMS1_HUMAN
NC score	0.029374 (rank : 121)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	174	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

CT043_MOUSE
NC score	0.029228 (rank : 122)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	174	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q99K95, Q543D3, Q80X88, Q9CV27	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf43 homolog.

CHD9_MOUSE
NC score	0.029081 (rank : 123)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	174	Target Neighborhood Hits	427	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

I15RA_HUMAN
NC score	0.028260 (rank : 124)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	174	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q13261, Q6B0J2, Q7LDR4, Q7Z609	Gene names	IL15RA
Domain Architecture	No domain graphic available
Description	Interleukin-15 receptor alpha chain precursor (IL-15R-alpha) (IL- 15RA).

IF4B_MOUSE
NC score	0.028076 (rank : 125)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	174	Target Neighborhood Hits	368	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

KLC3_HUMAN
NC score	0.027555 (rank : 126)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	174	Target Neighborhood Hits	137	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P597, Q6GMU2, Q8NAL1, Q8WWJ9	Gene names	KLC3, KLC2, KLC2L
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3 (kinesin light chain 2) (KLC2-like).

SETD2_HUMAN
NC score	0.027062 (rank : 127)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	174	Target Neighborhood Hits	412	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

NCOA6_HUMAN
NC score	0.026382 (rank : 128)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	174	Target Neighborhood Hits	1202	Shared Neighborhood Hits	33
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

HCDH_MOUSE
NC score	0.025843 (rank : 129)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	174	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q61425, Q3TF75, Q3THK8, Q3UFI0, Q8K149, Q925U9	Gene names	Hadhsc, Hadh, Mschad, Schad
Domain Architecture
Description	Short chain 3-hydroxyacyl-CoA dehydrogenase, mitochondrial precursor (EC 1.1.1.35) (HCDH) (Medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase).

CA026_MOUSE
NC score	0.025316 (rank : 130)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	174	Target Neighborhood Hits	100	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DBQ9, Q6PAN2, Q7TMQ6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf26 homolog.

UBP2L_HUMAN
NC score	0.025157 (rank : 131)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	174	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

BRCA1_HUMAN
NC score	0.024910 (rank : 132)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	174	Target Neighborhood Hits	381	Shared Neighborhood Hits	14
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

RAB3I_HUMAN
NC score	0.024762 (rank : 133)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	174	Target Neighborhood Hits	270	Shared Neighborhood Hits	16
SwissProt Accessions	Q96QF0, Q6PCE4, Q96A24, Q96QE6, Q96QE7, Q96QE8, Q96QE9, Q96QF1, Q9H673	Gene names	RAB3IP
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

TSH2_MOUSE
NC score	0.024479 (rank : 134)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	174	Target Neighborhood Hits	467	Shared Neighborhood Hits	10
SwissProt Accessions	Q68FE9, Q5DTF1, Q6AXH5, Q9JL71	Gene names	Tshz2, Kiaa4248, Sdccag33l, Tsh2, Zfp218, Znf218
Domain Architecture	No domain graphic available
Description	Teashirt homolog 2 (Zinc finger protein 218) (SDCCAG33-like protein).

PRP4B_MOUSE
NC score	0.024432 (rank : 135)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	174	Target Neighborhood Hits	1040	Shared Neighborhood Hits	31
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

AATM_MOUSE
NC score	0.023862 (rank : 136)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	174	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	P05202, O09188	Gene names	Got2, Got-2
Domain Architecture
Description	Aspartate aminotransferase, mitochondrial precursor (EC 2.6.1.1) (Transaminase A) (Glutamate oxaloacetate transaminase 2).

NOL8_MOUSE
NC score	0.023551 (rank : 137)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	174	Target Neighborhood Hits	210	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

FKSG2_HUMAN
NC score	0.022342 (rank : 138)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	174	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HAU6	Gene names	FKSG2
Domain Architecture
Description	Apoptosis inhibitor FKSG2.

EPIPL_HUMAN
NC score	0.021823 (rank : 139)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	174	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	P58107, Q76E58	Gene names	EPPK1, EPIPL
Domain Architecture
Description	Epiplakin (450 kDa epidermal antigen).

ANC1_MOUSE
NC score	0.021697 (rank : 140)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	174	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	P53995, Q8BP33, Q8C772	Gene names	Anapc1, Mcpr, Tsg24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

ANC1_HUMAN
NC score	0.021525 (rank : 141)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	174	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1A4, Q9BSE6, Q9H8D0	Gene names	ANAPC1, TSG24
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Protein Tsg24) (Mitotic checkpoint regulator).

RNS10_MOUSE
NC score	0.021196 (rank : 142)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	174	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D5A9, Q6XL64	Gene names	Rnase10
Domain Architecture	No domain graphic available
Description	Ribonuclease-like protein 10 precursor (Protein Train A).

ANK2_HUMAN
NC score	0.020845 (rank : 143)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	174	Target Neighborhood Hits	1615	Shared Neighborhood Hits	61
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

STC2_HUMAN
NC score	0.020707 (rank : 144)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	174	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	O76061	Gene names	STC2
Domain Architecture
Description	Stanniocalcin-2 precursor (STC-2) (Stanniocalcin-related protein) (STCRP) (STC-related protein).

BARD1_MOUSE
NC score	0.020365 (rank : 145)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	174	Target Neighborhood Hits	411	Shared Neighborhood Hits	9
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

PRP4B_HUMAN
NC score	0.020104 (rank : 146)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	174	Target Neighborhood Hits	1030	Shared Neighborhood Hits	31
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

K22E_HUMAN
NC score	0.019548 (rank : 147)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	174	Target Neighborhood Hits	515	Shared Neighborhood Hits	25
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

DVL1_MOUSE
NC score	0.018723 (rank : 148)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	174	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

BUB1_HUMAN
NC score	0.018143 (rank : 149)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	174	Target Neighborhood Hits	543	Shared Neighborhood Hits	15
SwissProt Accessions	O43683, O43430, O43643, O60626	Gene names	BUB1, BUB1L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 2.7.11.1) (hBUB1) (BUB1A).

DVL1L_HUMAN
NC score	0.017620 (rank : 150)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	174	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	P54792	Gene names	DVL1L1, DVL, DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1-like (Dishevelled- 1-like) (DSH homolog 1-like).

LAMA1_MOUSE
NC score	0.017550 (rank : 151)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	174	Target Neighborhood Hits	838	Shared Neighborhood Hits	27
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

CCNB3_MOUSE
NC score	0.017536 (rank : 152)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	174	Target Neighborhood Hits	211	Shared Neighborhood Hits	19
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

IMB1_MOUSE
NC score	0.017466 (rank : 153)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	174	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

DVL1_HUMAN
NC score	0.017324 (rank : 154)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	174	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	O14640	Gene names	DVL1
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

BMPR2_HUMAN
NC score	0.017295 (rank : 155)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	174	Target Neighborhood Hits	736	Shared Neighborhood Hits	7
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

POLI_MOUSE
NC score	0.017138 (rank : 156)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	174	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

SFRP2_MOUSE
NC score	0.016916 (rank : 157)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	174	Target Neighborhood Hits	47	Shared Neighborhood Hits	3
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

CAPS2_HUMAN
NC score	0.016256 (rank : 158)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	174	Target Neighborhood Hits	81	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

SFRP2_HUMAN
NC score	0.015589 (rank : 159)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	174	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

BMPR2_MOUSE
NC score	0.014654 (rank : 160)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	174	Target Neighborhood Hits	738	Shared Neighborhood Hits	8
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

ITB6_HUMAN
NC score	0.014374 (rank : 161)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	174	Target Neighborhood Hits	318	Shared Neighborhood Hits	5
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

SHAN2_HUMAN
NC score	0.014249 (rank : 162)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	174	Target Neighborhood Hits	346	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

HSP7C_MOUSE
NC score	0.014099 (rank : 163)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	174	Target Neighborhood Hits	166	Shared Neighborhood Hits	20
SwissProt Accessions	P63017, P08109, P12225, Q62373, Q62374, Q62375	Gene names	Hspa8, Hsc70, Hsc73
Domain Architecture	No domain graphic available
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

HSP7C_HUMAN
NC score	0.013817 (rank : 164)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	174	Target Neighborhood Hits	150	Shared Neighborhood Hits	19
SwissProt Accessions	P11142, Q9H3R6	Gene names	HSPA8, HSC70, HSP73, HSPA10
Domain Architecture
Description	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).

SYTL2_HUMAN
NC score	0.013534 (rank : 165)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	174	Target Neighborhood Hits	248	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

FUS_HUMAN
NC score	0.013348 (rank : 166)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	174	Target Neighborhood Hits	179	Shared Neighborhood Hits	4
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

BTBD7_MOUSE
NC score	0.013205 (rank : 167)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	174	Target Neighborhood Hits	228	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

ITF2_MOUSE
NC score	0.013073 (rank : 168)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	174	Target Neighborhood Hits	154	Shared Neighborhood Hits	10
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

CUZD1_MOUSE
NC score	0.012053 (rank : 169)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	174	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

SPB10_HUMAN
NC score	0.011845 (rank : 170)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	174	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P48595, Q4VAX4	Gene names	SERPINB10, PI10
Domain Architecture
Description	Serpin B10 (Bomapin) (Protease inhibitor 10).

NPT1_HUMAN
NC score	0.011079 (rank : 171)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	174	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q14916, Q13783	Gene names	SLC17A1, NPT1
Domain Architecture
Description	Sodium-dependent phosphate transport protein 1 (Sodium/phosphate cotransporter 1) (Na(+)/PI cotransporter 1) (Solute carrier family 17 member 1) (Renal sodium-dependent phosphate transport protein 1) (Renal sodium-phosphate transport protein 1) (Renal Na(+)-dependent phosphate cotransporter 1) (Na/Pi-4).

INADL_MOUSE
NC score	0.010989 (rank : 172)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	174	Target Neighborhood Hits	290	Shared Neighborhood Hits	8
SwissProt Accessions	Q63ZW7, O70471, Q5PRG3, Q6P6J1, Q80YR8, Q8BPB9	Gene names	Inadl, Cipp, Patj
Domain Architecture	No domain graphic available
Description	InaD-like protein (Inadl protein) (Pals1-associated tight junction protein) (Protein associated to tight junctions) (Channel-interacting PDZ domain-containing protein).

ANKK1_HUMAN
NC score	0.010753 (rank : 173)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	174	Target Neighborhood Hits	1075	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

TRIO_HUMAN
NC score	0.010317 (rank : 174)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	174	Target Neighborhood Hits	1580	Shared Neighborhood Hits	38
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

SPB10_MOUSE
NC score	0.009575 (rank : 175)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	174	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K1K6	Gene names	Serpinb10
Domain Architecture	No domain graphic available
Description	Serpin B10.

ZBTB6_MOUSE
NC score	0.009150 (rank : 176)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	174	Target Neighborhood Hits	793	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K088, Q8BLM4	Gene names	Zbtb6, Zfp482, Znf482
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482).

GSTM2_MOUSE
NC score	0.008337 (rank : 177)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	174	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P15626	Gene names	Gstm2
Domain Architecture
Description	Glutathione S-transferase Mu 2 (EC 2.5.1.18) (GST class-mu 2) (Glutathione S-transferase pmGT2) (GST 5-5).

ZBTB6_HUMAN
NC score	0.008036 (rank : 178)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	174	Target Neighborhood Hits	805	Shared Neighborhood Hits	14
SwissProt Accessions	Q15916	Gene names	ZBTB6, ZID, ZNF482
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482) (Zinc finger protein with interaction domain).

TCF8_HUMAN
NC score	0.008035 (rank : 179)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	174	Target Neighborhood Hits	1057	Shared Neighborhood Hits	30
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

SP3_HUMAN
NC score	0.007282 (rank : 180)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	174	Target Neighborhood Hits	737	Shared Neighborhood Hits	13
SwissProt Accessions	Q02447, Q8TD56, Q9BQR1	Gene names	SP3
Domain Architecture
Description	Transcription factor Sp3 (SPR-2).

FOXF1_MOUSE
NC score	0.007241 (rank : 181)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	174	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	Q61080, Q61661	Gene names	Foxf1, Fkhl5, Foxf1a, Freac1, Hfh8
Domain Architecture
Description	Forkhead box protein F1 (Forkhead-related protein FKHL5) (Forkhead- related transcription factor 1) (FREAC-1) (Hepatocyte nuclear factor 3 forkhead homolog 8) (HFH-8).

FOXF1_HUMAN
NC score	0.007204 (rank : 182)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	174	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q12946, Q5FWE5	Gene names	FOXF1, FKHL5, FREAC1
Domain Architecture
Description	Forkhead box protein F1 (Forkhead-related protein FKHL5) (Forkhead- related transcription factor 1) (FREAC-1) (Forkhead-related activator 1).

SP3_MOUSE
NC score	0.006341 (rank : 183)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	174	Target Neighborhood Hits	731	Shared Neighborhood Hits	13
SwissProt Accessions	O70494, Q68FF2, Q8CF64, Q8K378	Gene names	Sp3
Domain Architecture	No domain graphic available
Description	Transcription factor Sp3.

MASTL_MOUSE
NC score	0.006198 (rank : 184)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	174	Target Neighborhood Hits	862	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

ABLM1_HUMAN
NC score	0.005116 (rank : 185)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	174	Target Neighborhood Hits	387	Shared Neighborhood Hits	5
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

VLDLR_HUMAN
NC score	0.003962 (rank : 186)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	174	Target Neighborhood Hits	383	Shared Neighborhood Hits	5
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ZFP37_HUMAN
NC score	0.003668 (rank : 187)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	174	Target Neighborhood Hits	797	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6Q3	Gene names	ZFP37
Domain Architecture
Description	Zinc finger protein 37 homolog (Zfp-37).

ZN577_HUMAN
NC score	0.003519 (rank : 188)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	174	Target Neighborhood Hits	748	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BSK1	Gene names	ZNF577
Domain Architecture	No domain graphic available
Description	Zinc finger protein 577.

ROR1_HUMAN
NC score	0.003105 (rank : 189)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	174	Target Neighborhood Hits	1018	Shared Neighborhood Hits	9
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ZN700_HUMAN
NC score	0.002446 (rank : 190)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	174	Target Neighborhood Hits	772	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H0M5	Gene names	ZNF700
Domain Architecture	No domain graphic available
Description	Zinc finger protein 700.