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Network neighborhood for query Sequence : SMOC2_MOUSE

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SMOC2_MOUSE
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMOC2_HUMAN
θ value	0 (rank : 1)	NC score	0.996339 (rank : 2)
Query Neighborhood Hits	81	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	81	Target Neighborhood Hits	81	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC1_HUMAN
θ value	2.97994e-128 (rank : 3)	NC score	0.974760 (rank : 3)
Query Neighborhood Hits	81	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
θ value	1.80787e-125 (rank : 4)	NC score	0.972557 (rank : 4)
Query Neighborhood Hits	81	Target Neighborhood Hits	74	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

NID2_HUMAN
θ value	1.99529e-15 (rank : 5)	NC score	0.278386 (rank : 39)
Query Neighborhood Hits	81	Target Neighborhood Hits	456	Shared Neighborhood Hits	37
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	1.99529e-15 (rank : 6)	NC score	0.278918 (rank : 38)
Query Neighborhood Hits	81	Target Neighborhood Hits	338	Shared Neighborhood Hits	36
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

THYG_HUMAN
θ value	2.60593e-15 (rank : 7)	NC score	0.369060 (rank : 20)
Query Neighborhood Hits	81	Target Neighborhood Hits	154	Shared Neighborhood Hits	34
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

THYG_MOUSE
θ value	1.09485e-13 (rank : 8)	NC score	0.352299 (rank : 26)
Query Neighborhood Hits	81	Target Neighborhood Hits	161	Shared Neighborhood Hits	34
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TICN2_MOUSE
θ value	3.64472e-09 (rank : 9)	NC score	0.527447 (rank : 6)
Query Neighborhood Hits	81	Target Neighborhood Hits	69	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

NID1_HUMAN
θ value	1.80886e-08 (rank : 10)	NC score	0.247822 (rank : 42)
Query Neighborhood Hits	81	Target Neighborhood Hits	329	Shared Neighborhood Hits	35
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TICN2_HUMAN
θ value	5.26297e-08 (rank : 11)	NC score	0.524830 (rank : 7)
Query Neighborhood Hits	81	Target Neighborhood Hits	68	Shared Neighborhood Hits	53
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

NID1_MOUSE
θ value	6.87365e-08 (rank : 12)	NC score	0.243673 (rank : 43)
Query Neighborhood Hits	81	Target Neighborhood Hits	335	Shared Neighborhood Hits	34
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

HG2A_MOUSE
θ value	7.59969e-07 (rank : 13)	NC score	0.537840 (rank : 5)
Query Neighborhood Hits	81	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

TICN1_HUMAN
θ value	2.21117e-06 (rank : 14)	NC score	0.491329 (rank : 9)
Query Neighborhood Hits	81	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_MOUSE
θ value	2.21117e-06 (rank : 15)	NC score	0.489315 (rank : 10)
Query Neighborhood Hits	81	Target Neighborhood Hits	79	Shared Neighborhood Hits	51
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

IBP1_MOUSE
θ value	8.40245e-06 (rank : 16)	NC score	0.379833 (rank : 18)
Query Neighborhood Hits	81	Target Neighborhood Hits	97	Shared Neighborhood Hits	32
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

HG2A_HUMAN
θ value	1.09739e-05 (rank : 17)	NC score	0.492474 (rank : 8)
Query Neighborhood Hits	81	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

FST_HUMAN
θ value	1.43324e-05 (rank : 18)	NC score	0.355787 (rank : 25)
Query Neighborhood Hits	81	Target Neighborhood Hits	129	Shared Neighborhood Hits	34
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	1.43324e-05 (rank : 19)	NC score	0.348472 (rank : 28)
Query Neighborhood Hits	81	Target Neighborhood Hits	146	Shared Neighborhood Hits	34
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

IBP1_HUMAN
θ value	4.1701e-05 (rank : 20)	NC score	0.403707 (rank : 13)
Query Neighborhood Hits	81	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

TICN3_HUMAN
θ value	4.1701e-05 (rank : 21)	NC score	0.478900 (rank : 11)
Query Neighborhood Hits	81	Target Neighborhood Hits	82	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TEFF2_HUMAN
θ value	5.44631e-05 (rank : 22)	NC score	0.297494 (rank : 34)
Query Neighborhood Hits	81	Target Neighborhood Hits	211	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	5.44631e-05 (rank : 23)	NC score	0.297292 (rank : 35)
Query Neighborhood Hits	81	Target Neighborhood Hits	214	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TICN3_MOUSE
θ value	5.44631e-05 (rank : 24)	NC score	0.476554 (rank : 12)
Query Neighborhood Hits	81	Target Neighborhood Hits	83	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

SPRC_MOUSE
θ value	9.29e-05 (rank : 25)	NC score	0.359444 (rank : 23)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

IBP3_HUMAN
θ value	0.000121331 (rank : 26)	NC score	0.399906 (rank : 14)
Query Neighborhood Hits	81	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

SPRC_HUMAN
θ value	0.000158464 (rank : 27)	NC score	0.357769 (rank : 24)
Query Neighborhood Hits	81	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

AGRIN_HUMAN
θ value	0.00020696 (rank : 28)	NC score	0.164703 (rank : 47)
Query Neighborhood Hits	81	Target Neighborhood Hits	582	Shared Neighborhood Hits	41
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

IBP2_MOUSE
θ value	0.00035302 (rank : 29)	NC score	0.376611 (rank : 19)
Query Neighborhood Hits	81	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

SPRL1_MOUSE
θ value	0.00035302 (rank : 30)	NC score	0.282080 (rank : 37)
Query Neighborhood Hits	81	Target Neighborhood Hits	403	Shared Neighborhood Hits	24
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

FSTL3_HUMAN
θ value	0.000461057 (rank : 31)	NC score	0.337345 (rank : 30)
Query Neighborhood Hits	81	Target Neighborhood Hits	162	Shared Neighborhood Hits	37
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

IBP4_HUMAN
θ value	0.000461057 (rank : 32)	NC score	0.384020 (rank : 17)
Query Neighborhood Hits	81	Target Neighborhood Hits	52	Shared Neighborhood Hits	37
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
θ value	0.000461057 (rank : 33)	NC score	0.386066 (rank : 15)
Query Neighborhood Hits	81	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

SPRL1_HUMAN
θ value	0.000786445 (rank : 34)	NC score	0.305558 (rank : 33)
Query Neighborhood Hits	81	Target Neighborhood Hits	231	Shared Neighborhood Hits	27
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

IBP3_MOUSE
θ value	0.00134147 (rank : 35)	NC score	0.366622 (rank : 22)
Query Neighborhood Hits	81	Target Neighborhood Hits	60	Shared Neighborhood Hits	35
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP2_HUMAN
θ value	0.00390308 (rank : 36)	NC score	0.350997 (rank : 27)
Query Neighborhood Hits	81	Target Neighborhood Hits	61	Shared Neighborhood Hits	35
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP6_HUMAN
θ value	0.00509761 (rank : 37)	NC score	0.385022 (rank : 16)
Query Neighborhood Hits	81	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP6_MOUSE
θ value	0.00665767 (rank : 38)	NC score	0.368461 (rank : 21)
Query Neighborhood Hits	81	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

FSTL3_MOUSE
θ value	0.0148317 (rank : 39)	NC score	0.310884 (rank : 32)
Query Neighborhood Hits	81	Target Neighborhood Hits	152	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

KAZD1_MOUSE
θ value	0.0193708 (rank : 40)	NC score	0.162070 (rank : 48)
Query Neighborhood Hits	81	Target Neighborhood Hits	281	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

FSTL1_MOUSE
θ value	0.0330416 (rank : 41)	NC score	0.270459 (rank : 40)
Query Neighborhood Hits	81	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL1_HUMAN
θ value	0.0431538 (rank : 42)	NC score	0.270033 (rank : 41)
Query Neighborhood Hits	81	Target Neighborhood Hits	68	Shared Neighborhood Hits	34
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

KAZD1_HUMAN
θ value	0.0431538 (rank : 43)	NC score	0.165535 (rank : 46)
Query Neighborhood Hits	81	Target Neighborhood Hits	248	Shared Neighborhood Hits	38
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

IBP5_HUMAN
θ value	0.0563607 (rank : 44)	NC score	0.337402 (rank : 29)
Query Neighborhood Hits	81	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

FSTL5_MOUSE
θ value	0.0961366 (rank : 45)	NC score	0.108316 (rank : 52)
Query Neighborhood Hits	81	Target Neighborhood Hits	355	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

GUC1C_HUMAN
θ value	0.125558 (rank : 46)	NC score	0.071115 (rank : 64)
Query Neighborhood Hits	81	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

IBP5_MOUSE
θ value	0.125558 (rank : 47)	NC score	0.334217 (rank : 31)
Query Neighborhood Hits	81	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

TACD1_HUMAN
θ value	0.125558 (rank : 48)	NC score	0.289444 (rank : 36)
Query Neighborhood Hits	81	Target Neighborhood Hits	34	Shared Neighborhood Hits	31
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

CFAI_MOUSE
θ value	0.163984 (rank : 49)	NC score	0.030604 (rank : 91)
Query Neighborhood Hits	81	Target Neighborhood Hits	290	Shared Neighborhood Hits	14
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

FSTL5_HUMAN
θ value	0.163984 (rank : 50)	NC score	0.108768 (rank : 51)
Query Neighborhood Hits	81	Target Neighborhood Hits	347	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

ISK6_MOUSE
θ value	0.163984 (rank : 51)	NC score	0.202337 (rank : 45)
Query Neighborhood Hits	81	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

ANKY1_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.034354 (rank : 89)
Query Neighborhood Hits	81	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

KCIP2_MOUSE
θ value	0.62314 (rank : 53)	NC score	0.058198 (rank : 69)
Query Neighborhood Hits	81	Target Neighborhood Hits	124	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJ69, Q6DTJ2, Q8K1T8, Q8K1T9, Q8K1U0, Q8VHN4, Q8VHN5, Q8VHN6, Q9JJ68	Gene names	Kcnip2, Kchip2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2).

GP152_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.014385 (rank : 98)
Query Neighborhood Hits	81	Target Neighborhood Hits	636	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

KCIP2_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.057089 (rank : 72)
Query Neighborhood Hits	81	Target Neighborhood Hits	125	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NS61, Q7Z6F1, Q96K86, Q96T41, Q96T42, Q96T43, Q96T44, Q9H0N4, Q9HD10, Q9HD11, Q9NS60, Q9NY10, Q9NZI1	Gene names	KCNIP2, KCHIP2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2) (Cardiac voltage-gated potassium channel modulatory subunit).

SO1A2_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.020374 (rank : 95)
Query Neighborhood Hits	81	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

TACD2_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.240177 (rank : 44)
Query Neighborhood Hits	81	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

KCIP4_HUMAN
θ value	1.06291 (rank : 58)	NC score	0.055928 (rank : 73)
Query Neighborhood Hits	81	Target Neighborhood Hits	136	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PIL6, Q4W5G8, Q8NEU0, Q9BWT2, Q9H294, Q9H2A4	Gene names	KCNIP4, CALP, KCHIP4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

KCIP4_MOUSE
θ value	1.06291 (rank : 59)	NC score	0.055914 (rank : 74)
Query Neighborhood Hits	81	Target Neighborhood Hits	136	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PHZ8, Q6DTJ3, Q8CAD0, Q8R4I2, Q9EQ01	Gene names	Kcnip4, Calp, Kchip4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

CSEN_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.053442 (rank : 78)
Query Neighborhood Hits	81	Target Neighborhood Hits	128	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2W7, Q53TJ5, Q96T40, Q9UJ84, Q9UJ85	Gene names	KCNIP3, CSEN, DREAM, KCHIP3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3).

ESCO1_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.026905 (rank : 92)
Query Neighborhood Hits	81	Target Neighborhood Hits	361	Shared Neighborhood Hits	3
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

TULP1_MOUSE
θ value	1.38821 (rank : 62)	NC score	0.023394 (rank : 93)
Query Neighborhood Hits	81	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

ISK5_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.121098 (rank : 50)
Query Neighborhood Hits	81	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

S10A9_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.032737 (rank : 90)
Query Neighborhood Hits	81	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	P06702, Q9NYM0, Q9UCJ1	Gene names	S100A9, CAGB, MRP14
Domain Architecture
Description	Protein S100-A9 (S100 calcium-binding protein A9) (Calgranulin-B) (Migration inhibitory factor-related protein 14) (MRP-14) (P14) (Leukocyte L1 complex heavy chain) (Calprotectin L1H subunit).

FSTL4_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.101504 (rank : 53)
Query Neighborhood Hits	81	Target Neighborhood Hits	333	Shared Neighborhood Hits	34
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

ISK6_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.129941 (rank : 49)
Query Neighborhood Hits	81	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

LAMA3_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.023160 (rank : 94)
Query Neighborhood Hits	81	Target Neighborhood Hits	859	Shared Neighborhood Hits	15
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

GUC1A_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.050982 (rank : 83)
Query Neighborhood Hits	81	Target Neighborhood Hits	152	Shared Neighborhood Hits	18
SwissProt Accessions	P43081	Gene names	Guca1a, Gcap, Gcap1, Guca1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

HPCA_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.046018 (rank : 85)
Query Neighborhood Hits	81	Target Neighborhood Hits	156	Shared Neighborhood Hits	17
SwissProt Accessions	P84074, P32076, P41211, P70510	Gene names	HPCA, BDR2
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2).

HPCA_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.046018 (rank : 86)
Query Neighborhood Hits	81	Target Neighborhood Hits	156	Shared Neighborhood Hits	17
SwissProt Accessions	P84075, P32076, P41211, P70510	Gene names	Hpca
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin.

HTRA1_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.101106 (rank : 55)
Query Neighborhood Hits	81	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

KCIP1_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.051351 (rank : 81)
Query Neighborhood Hits	81	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZI2, Q5U822	Gene names	KCNIP1, KCHIP1, VABP
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein).

KCIP1_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.051275 (rank : 82)
Query Neighborhood Hits	81	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJ57, Q5SSA3, Q6DTJ1, Q8BGJ4, Q8C4K4, Q8CGL1, Q8K1U1, Q8K3M2	Gene names	Kcnip1, Kchip1
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1).

FSTL4_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.101293 (rank : 54)
Query Neighborhood Hits	81	Target Neighborhood Hits	344	Shared Neighborhood Hits	34
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

CSEN_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.047948 (rank : 84)
Query Neighborhood Hits	81	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXT8, Q924L0, Q99PH9, Q99PI0, Q99PI2, Q99PI3, Q9JHZ5	Gene names	Kcnip3, Csen, Dream, Kchip3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (A-type potassium channel modulatory protein 3) (KChIP3).

HPCL1_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.043228 (rank : 88)
Query Neighborhood Hits	81	Target Neighborhood Hits	150	Shared Neighborhood Hits	17
SwissProt Accessions	P37235, Q969S5	Gene names	HPCAL1, BDR1
Domain Architecture
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Calcium-binding protein BDR-1) (HLP2).

HPCL1_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.043535 (rank : 87)
Query Neighborhood Hits	81	Target Neighborhood Hits	149	Shared Neighborhood Hits	18
SwissProt Accessions	P62748, P35333	Gene names	Hpcal1
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Neural visinin-like protein 3) (NVL-3) (NVP-3).

PASK_MOUSE
θ value	6.88961 (rank : 78)	NC score	-0.002349 (rank : 100)
Query Neighborhood Hits	81	Target Neighborhood Hits	867	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).

CYGB_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.014546 (rank : 97)
Query Neighborhood Hits	81	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CX80	Gene names	Cygb
Domain Architecture
Description	Cytoglobin (Histoglobin) (HGb).

LAMA2_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.016819 (rank : 96)
Query Neighborhood Hits	81	Target Neighborhood Hits	1092	Shared Neighborhood Hits	13
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

PKP3_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.010955 (rank : 99)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

EGF_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.055144 (rank : 75)
Query Neighborhood Hits	81	Target Neighborhood Hits	343	Shared Neighborhood Hits	9
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.055070 (rank : 76)
Query Neighborhood Hits	81	Target Neighborhood Hits	358	Shared Neighborhood Hits	9
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

HTRA1_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.085455 (rank : 59)
Query Neighborhood Hits	81	Target Neighborhood Hits	155	Shared Neighborhood Hits	33
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

IBP7_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.085878 (rank : 58)
Query Neighborhood Hits	81	Target Neighborhood Hits	220	Shared Neighborhood Hits	29
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.079918 (rank : 61)
Query Neighborhood Hits	81	Target Neighborhood Hits	230	Shared Neighborhood Hits	27
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

IPK1_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.082437 (rank : 60)
Query Neighborhood Hits	81	Target Neighborhood Hits	38	Shared Neighborhood Hits	20
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

IPK2_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.061284 (rank : 65)
Query Neighborhood Hits	81	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

ISK3_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.059559 (rank : 66)
Query Neighborhood Hits	81	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

ISK4_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.095810 (rank : 57)
Query Neighborhood Hits	81	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

ISK4_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.100355 (rank : 56)
Query Neighborhood Hits	81	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

ISK7_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.072625 (rank : 63)
Query Neighborhood Hits	81	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

ISK7_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.073569 (rank : 62)
Query Neighborhood Hits	81	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

LRP5_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.059216 (rank : 67)
Query Neighborhood Hits	81	Target Neighborhood Hits	224	Shared Neighborhood Hits	7
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.058955 (rank : 68)
Query Neighborhood Hits	81	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.057309 (rank : 70)
Query Neighborhood Hits	81	Target Neighborhood Hits	235	Shared Neighborhood Hits	5
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.057247 (rank : 71)
Query Neighborhood Hits	81	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

RECK_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.051794 (rank : 79)
Query Neighborhood Hits	81	Target Neighborhood Hits	189	Shared Neighborhood Hits	24
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TECTA_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.053558 (rank : 77)
Query Neighborhood Hits	81	Target Neighborhood Hits	239	Shared Neighborhood Hits	7
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.051438 (rank : 80)
Query Neighborhood Hits	81	Target Neighborhood Hits	244	Shared Neighborhood Hits	7
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

Hits sorted by NC score

SMOC2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	81	Target Neighborhood Hits	81	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC2_HUMAN
NC score	0.996339 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	81	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC1_HUMAN
NC score	0.974760 (rank : 3)	θ value	2.97994e-128 (rank : 3)
Query Neighborhood Hits	81	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
NC score	0.972557 (rank : 4)	θ value	1.80787e-125 (rank : 4)
Query Neighborhood Hits	81	Target Neighborhood Hits	74	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

HG2A_MOUSE
NC score	0.537840 (rank : 5)	θ value	7.59969e-07 (rank : 13)
Query Neighborhood Hits	81	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

TICN2_MOUSE
NC score	0.527447 (rank : 6)	θ value	3.64472e-09 (rank : 9)
Query Neighborhood Hits	81	Target Neighborhood Hits	69	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_HUMAN
NC score	0.524830 (rank : 7)	θ value	5.26297e-08 (rank : 11)
Query Neighborhood Hits	81	Target Neighborhood Hits	68	Shared Neighborhood Hits	53
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

HG2A_HUMAN
NC score	0.492474 (rank : 8)	θ value	1.09739e-05 (rank : 17)
Query Neighborhood Hits	81	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

TICN1_HUMAN
NC score	0.491329 (rank : 9)	θ value	2.21117e-06 (rank : 14)
Query Neighborhood Hits	81	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_MOUSE
NC score	0.489315 (rank : 10)	θ value	2.21117e-06 (rank : 15)
Query Neighborhood Hits	81	Target Neighborhood Hits	79	Shared Neighborhood Hits	51
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN3_HUMAN
NC score	0.478900 (rank : 11)	θ value	4.1701e-05 (rank : 21)
Query Neighborhood Hits	81	Target Neighborhood Hits	82	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_MOUSE
NC score	0.476554 (rank : 12)	θ value	5.44631e-05 (rank : 24)
Query Neighborhood Hits	81	Target Neighborhood Hits	83	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

IBP1_HUMAN
NC score	0.403707 (rank : 13)	θ value	4.1701e-05 (rank : 20)
Query Neighborhood Hits	81	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP3_HUMAN
NC score	0.399906 (rank : 14)	θ value	0.000121331 (rank : 26)
Query Neighborhood Hits	81	Target Neighborhood Hits	67	Shared Neighborhood Hits	35
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP4_MOUSE
NC score	0.386066 (rank : 15)	θ value	0.000461057 (rank : 33)
Query Neighborhood Hits	81	Target Neighborhood Hits	55	Shared Neighborhood Hits	37
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP6_HUMAN
NC score	0.385022 (rank : 16)	θ value	0.00509761 (rank : 37)
Query Neighborhood Hits	81	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP4_HUMAN
NC score	0.384020 (rank : 17)	θ value	0.000461057 (rank : 32)
Query Neighborhood Hits	81	Target Neighborhood Hits	52	Shared Neighborhood Hits	37
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP1_MOUSE
NC score	0.379833 (rank : 18)	θ value	8.40245e-06 (rank : 16)
Query Neighborhood Hits	81	Target Neighborhood Hits	97	Shared Neighborhood Hits	32
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP2_MOUSE
NC score	0.376611 (rank : 19)	θ value	0.00035302 (rank : 29)
Query Neighborhood Hits	81	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

THYG_HUMAN
NC score	0.369060 (rank : 20)	θ value	2.60593e-15 (rank : 7)
Query Neighborhood Hits	81	Target Neighborhood Hits	154	Shared Neighborhood Hits	34
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

IBP6_MOUSE
NC score	0.368461 (rank : 21)	θ value	0.00665767 (rank : 38)
Query Neighborhood Hits	81	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP3_MOUSE
NC score	0.366622 (rank : 22)	θ value	0.00134147 (rank : 35)
Query Neighborhood Hits	81	Target Neighborhood Hits	60	Shared Neighborhood Hits	35
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

SPRC_MOUSE
NC score	0.359444 (rank : 23)	θ value	9.29e-05 (rank : 25)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_HUMAN
NC score	0.357769 (rank : 24)	θ value	0.000158464 (rank : 27)
Query Neighborhood Hits	81	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

FST_HUMAN
NC score	0.355787 (rank : 25)	θ value	1.43324e-05 (rank : 18)
Query Neighborhood Hits	81	Target Neighborhood Hits	129	Shared Neighborhood Hits	34
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

THYG_MOUSE
NC score	0.352299 (rank : 26)	θ value	1.09485e-13 (rank : 8)
Query Neighborhood Hits	81	Target Neighborhood Hits	161	Shared Neighborhood Hits	34
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

IBP2_HUMAN
NC score	0.350997 (rank : 27)	θ value	0.00390308 (rank : 36)
Query Neighborhood Hits	81	Target Neighborhood Hits	61	Shared Neighborhood Hits	35
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

FST_MOUSE
NC score	0.348472 (rank : 28)	θ value	1.43324e-05 (rank : 19)
Query Neighborhood Hits	81	Target Neighborhood Hits	146	Shared Neighborhood Hits	34
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

IBP5_HUMAN
NC score	0.337402 (rank : 29)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	81	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

FSTL3_HUMAN
NC score	0.337345 (rank : 30)	θ value	0.000461057 (rank : 31)
Query Neighborhood Hits	81	Target Neighborhood Hits	162	Shared Neighborhood Hits	37
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

IBP5_MOUSE
NC score	0.334217 (rank : 31)	θ value	0.125558 (rank : 47)
Query Neighborhood Hits	81	Target Neighborhood Hits	68	Shared Neighborhood Hits	35
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

FSTL3_MOUSE
NC score	0.310884 (rank : 32)	θ value	0.0148317 (rank : 39)
Query Neighborhood Hits	81	Target Neighborhood Hits	152	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

SPRL1_HUMAN
NC score	0.305558 (rank : 33)	θ value	0.000786445 (rank : 34)
Query Neighborhood Hits	81	Target Neighborhood Hits	231	Shared Neighborhood Hits	27
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

TEFF2_HUMAN
NC score	0.297494 (rank : 34)	θ value	5.44631e-05 (rank : 22)
Query Neighborhood Hits	81	Target Neighborhood Hits	211	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
NC score	0.297292 (rank : 35)	θ value	5.44631e-05 (rank : 23)
Query Neighborhood Hits	81	Target Neighborhood Hits	214	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TACD1_HUMAN
NC score	0.289444 (rank : 36)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	81	Target Neighborhood Hits	34	Shared Neighborhood Hits	31
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

SPRL1_MOUSE
NC score	0.282080 (rank : 37)	θ value	0.00035302 (rank : 30)
Query Neighborhood Hits	81	Target Neighborhood Hits	403	Shared Neighborhood Hits	24
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

NID2_MOUSE
NC score	0.278918 (rank : 38)	θ value	1.99529e-15 (rank : 6)
Query Neighborhood Hits	81	Target Neighborhood Hits	338	Shared Neighborhood Hits	36
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID2_HUMAN
NC score	0.278386 (rank : 39)	θ value	1.99529e-15 (rank : 5)
Query Neighborhood Hits	81	Target Neighborhood Hits	456	Shared Neighborhood Hits	37
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

FSTL1_MOUSE
NC score	0.270459 (rank : 40)	θ value	0.0330416 (rank : 41)
Query Neighborhood Hits	81	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL1_HUMAN
NC score	0.270033 (rank : 41)	θ value	0.0431538 (rank : 42)
Query Neighborhood Hits	81	Target Neighborhood Hits	68	Shared Neighborhood Hits	34
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

NID1_HUMAN
NC score	0.247822 (rank : 42)	θ value	1.80886e-08 (rank : 10)
Query Neighborhood Hits	81	Target Neighborhood Hits	329	Shared Neighborhood Hits	35
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
NC score	0.243673 (rank : 43)	θ value	6.87365e-08 (rank : 12)
Query Neighborhood Hits	81	Target Neighborhood Hits	335	Shared Neighborhood Hits	34
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TACD2_HUMAN
NC score	0.240177 (rank : 44)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	81	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

ISK6_MOUSE
NC score	0.202337 (rank : 45)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	81	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BT20	Gene names	Spink6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

KAZD1_HUMAN
NC score	0.165535 (rank : 46)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	81	Target Neighborhood Hits	248	Shared Neighborhood Hits	38
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

AGRIN_HUMAN
NC score	0.164703 (rank : 47)	θ value	0.00020696 (rank : 28)
Query Neighborhood Hits	81	Target Neighborhood Hits	582	Shared Neighborhood Hits	41
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

KAZD1_MOUSE
NC score	0.162070 (rank : 48)	θ value	0.0193708 (rank : 40)
Query Neighborhood Hits	81	Target Neighborhood Hits	281	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

ISK6_HUMAN
NC score	0.129941 (rank : 49)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	81	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UWN8, Q8N5P0	Gene names	SPINK6
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 6 precursor.

ISK5_HUMAN
NC score	0.121098 (rank : 50)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	81	Target Neighborhood Hits	89	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NQ38, O75770, Q96PP2, Q96PP3	Gene names	SPINK5
Domain Architecture
Description	Serine protease inhibitor Kazal-type 5 precursor (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Contains: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665].

FSTL5_HUMAN
NC score	0.108768 (rank : 51)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	81	Target Neighborhood Hits	347	Shared Neighborhood Hits	31
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
NC score	0.108316 (rank : 52)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	81	Target Neighborhood Hits	355	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FSTL4_MOUSE
NC score	0.101504 (rank : 53)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	81	Target Neighborhood Hits	333	Shared Neighborhood Hits	34
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL4_HUMAN
NC score	0.101293 (rank : 54)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	81	Target Neighborhood Hits	344	Shared Neighborhood Hits	34
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

HTRA1_MOUSE
NC score	0.101106 (rank : 55)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	81	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

ISK4_MOUSE
NC score	0.100355 (rank : 56)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	81	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	O35679	Gene names	Spink4, Mpgc60
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog) (MPGC60 protein).

ISK4_HUMAN
NC score	0.095810 (rank : 57)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	81	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	O60575	Gene names	SPINK4
Domain Architecture
Description	Serine protease inhibitor Kazal-type 4 precursor (Peptide PEC-60 homolog).

IBP7_HUMAN
NC score	0.085878 (rank : 58)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	81	Target Neighborhood Hits	220	Shared Neighborhood Hits	29
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

HTRA1_HUMAN
NC score	0.085455 (rank : 59)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	81	Target Neighborhood Hits	155	Shared Neighborhood Hits	33
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

IPK1_HUMAN
NC score	0.082437 (rank : 60)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	81	Target Neighborhood Hits	38	Shared Neighborhood Hits	20
SwissProt Accessions	P00995	Gene names	SPINK1, PSTI
Domain Architecture
Description	Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).

IBP7_MOUSE
NC score	0.079918 (rank : 61)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	81	Target Neighborhood Hits	230	Shared Neighborhood Hits	27
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ISK7_MOUSE
NC score	0.073569 (rank : 62)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	81	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q6IE32	Gene names	Spink7, Ecg2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

ISK7_HUMAN
NC score	0.072625 (rank : 63)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	81	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	P58062	Gene names	SPINK7, ECG2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 7 precursor (Esophagus cancer- related gene 2 protein) (ECRG-2).

GUC1C_HUMAN
NC score	0.071115 (rank : 64)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	81	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

IPK2_HUMAN
NC score	0.061284 (rank : 65)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	81	Target Neighborhood Hits	30	Shared Neighborhood Hits	18
SwissProt Accessions	P20155	Gene names	SPINK2
Domain Architecture
Description	Serine protease inhibitor Kazal-type 2 precursor (Acrosin-trypsin inhibitor) (HUSI-II).

ISK3_MOUSE
NC score	0.059559 (rank : 66)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	81	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

LRP5_HUMAN
NC score	0.059216 (rank : 67)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	81	Target Neighborhood Hits	224	Shared Neighborhood Hits	7
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
NC score	0.058955 (rank : 68)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	81	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

KCIP2_MOUSE
NC score	0.058198 (rank : 69)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	81	Target Neighborhood Hits	124	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJ69, Q6DTJ2, Q8K1T8, Q8K1T9, Q8K1U0, Q8VHN4, Q8VHN5, Q8VHN6, Q9JJ68	Gene names	Kcnip2, Kchip2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2).

LRP6_HUMAN
NC score	0.057309 (rank : 70)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	81	Target Neighborhood Hits	235	Shared Neighborhood Hits	5
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
NC score	0.057247 (rank : 71)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	81	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

KCIP2_HUMAN
NC score	0.057089 (rank : 72)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	81	Target Neighborhood Hits	125	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NS61, Q7Z6F1, Q96K86, Q96T41, Q96T42, Q96T43, Q96T44, Q9H0N4, Q9HD10, Q9HD11, Q9NS60, Q9NY10, Q9NZI1	Gene names	KCNIP2, KCHIP2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2) (Cardiac voltage-gated potassium channel modulatory subunit).

KCIP4_HUMAN
NC score	0.055928 (rank : 73)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	81	Target Neighborhood Hits	136	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PIL6, Q4W5G8, Q8NEU0, Q9BWT2, Q9H294, Q9H2A4	Gene names	KCNIP4, CALP, KCHIP4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

KCIP4_MOUSE
NC score	0.055914 (rank : 74)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	81	Target Neighborhood Hits	136	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PHZ8, Q6DTJ3, Q8CAD0, Q8R4I2, Q9EQ01	Gene names	Kcnip4, Calp, Kchip4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

EGF_HUMAN
NC score	0.055144 (rank : 75)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	81	Target Neighborhood Hits	343	Shared Neighborhood Hits	9
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
NC score	0.055070 (rank : 76)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	81	Target Neighborhood Hits	358	Shared Neighborhood Hits	9
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

TECTA_HUMAN
NC score	0.053558 (rank : 77)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	81	Target Neighborhood Hits	239	Shared Neighborhood Hits	7
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

CSEN_HUMAN
NC score	0.053442 (rank : 78)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	81	Target Neighborhood Hits	128	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2W7, Q53TJ5, Q96T40, Q9UJ84, Q9UJ85	Gene names	KCNIP3, CSEN, DREAM, KCHIP3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3).

RECK_HUMAN
NC score	0.051794 (rank : 79)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	81	Target Neighborhood Hits	189	Shared Neighborhood Hits	24
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TECTA_MOUSE
NC score	0.051438 (rank : 80)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	81	Target Neighborhood Hits	244	Shared Neighborhood Hits	7
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

KCIP1_HUMAN
NC score	0.051351 (rank : 81)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	81	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZI2, Q5U822	Gene names	KCNIP1, KCHIP1, VABP
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein).

KCIP1_MOUSE
NC score	0.051275 (rank : 82)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	81	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJ57, Q5SSA3, Q6DTJ1, Q8BGJ4, Q8C4K4, Q8CGL1, Q8K1U1, Q8K3M2	Gene names	Kcnip1, Kchip1
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1).

GUC1A_MOUSE
NC score	0.050982 (rank : 83)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	81	Target Neighborhood Hits	152	Shared Neighborhood Hits	18
SwissProt Accessions	P43081	Gene names	Guca1a, Gcap, Gcap1, Guca1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

CSEN_MOUSE
NC score	0.047948 (rank : 84)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	81	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXT8, Q924L0, Q99PH9, Q99PI0, Q99PI2, Q99PI3, Q9JHZ5	Gene names	Kcnip3, Csen, Dream, Kchip3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (A-type potassium channel modulatory protein 3) (KChIP3).

HPCA_HUMAN
NC score	0.046018 (rank : 85)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	81	Target Neighborhood Hits	156	Shared Neighborhood Hits	17
SwissProt Accessions	P84074, P32076, P41211, P70510	Gene names	HPCA, BDR2
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2).

HPCA_MOUSE
NC score	0.046018 (rank : 86)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	81	Target Neighborhood Hits	156	Shared Neighborhood Hits	17
SwissProt Accessions	P84075, P32076, P41211, P70510	Gene names	Hpca
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin.

HPCL1_MOUSE
NC score	0.043535 (rank : 87)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	81	Target Neighborhood Hits	149	Shared Neighborhood Hits	18
SwissProt Accessions	P62748, P35333	Gene names	Hpcal1
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Neural visinin-like protein 3) (NVL-3) (NVP-3).

HPCL1_HUMAN
NC score	0.043228 (rank : 88)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	81	Target Neighborhood Hits	150	Shared Neighborhood Hits	17
SwissProt Accessions	P37235, Q969S5	Gene names	HPCAL1, BDR1
Domain Architecture
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Calcium-binding protein BDR-1) (HLP2).

ANKY1_HUMAN
NC score	0.034354 (rank : 89)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	81	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

S10A9_HUMAN
NC score	0.032737 (rank : 90)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	81	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	P06702, Q9NYM0, Q9UCJ1	Gene names	S100A9, CAGB, MRP14
Domain Architecture
Description	Protein S100-A9 (S100 calcium-binding protein A9) (Calgranulin-B) (Migration inhibitory factor-related protein 14) (MRP-14) (P14) (Leukocyte L1 complex heavy chain) (Calprotectin L1H subunit).

CFAI_MOUSE
NC score	0.030604 (rank : 91)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	81	Target Neighborhood Hits	290	Shared Neighborhood Hits	14
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

ESCO1_HUMAN
NC score	0.026905 (rank : 92)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	81	Target Neighborhood Hits	361	Shared Neighborhood Hits	3
SwissProt Accessions	Q5FWF5, Q69YG4, Q69YS3, Q6IMD7, Q8N3Z5, Q8NBG2, Q96PX7	Gene names	ESCO1, EFO1, KIAA1911
Domain Architecture	No domain graphic available
Description	N-acetyltransferase ESCO1 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) (Establishment factor- like protein 1) (EFO1p) (hEFO1) (CTF7 homolog 1).

TULP1_MOUSE
NC score	0.023394 (rank : 93)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	81	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z273	Gene names	Tulp1
Domain Architecture
Description	Tubby-related protein 1 (Tubby-like protein 1).

LAMA3_MOUSE
NC score	0.023160 (rank : 94)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	81	Target Neighborhood Hits	859	Shared Neighborhood Hits	15
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

SO1A2_HUMAN
NC score	0.020374 (rank : 95)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	81	Target Neighborhood Hits	40	Shared Neighborhood Hits	10
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

LAMA2_HUMAN
NC score	0.016819 (rank : 96)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	81	Target Neighborhood Hits	1092	Shared Neighborhood Hits	13
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CYGB_MOUSE
NC score	0.014546 (rank : 97)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	81	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CX80	Gene names	Cygb
Domain Architecture
Description	Cytoglobin (Histoglobin) (HGb).

GP152_HUMAN
NC score	0.014385 (rank : 98)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	81	Target Neighborhood Hits	636	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

PKP3_MOUSE
NC score	0.010955 (rank : 99)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY23	Gene names	Pkp3
Domain Architecture
Description	Plakophilin-3.

PASK_MOUSE
NC score	-0.002349 (rank : 100)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	81	Target Neighborhood Hits	867	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CEE6, Q91YD8	Gene names	Pask, Kiaa0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN).