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Network neighborhood for query Sequence : IBP6_MOUSE

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IBP6_MOUSE
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IBP6_MOUSE
θ value	9.28496e-122 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP6_HUMAN
θ value	4.98072e-83 (rank : 2)	NC score	0.982204 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP5_HUMAN
θ value	9.8567e-31 (rank : 3)	NC score	0.901383 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
θ value	1.28732e-30 (rank : 4)	NC score	0.900416 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP3_HUMAN
θ value	7.80994e-28 (rank : 5)	NC score	0.894910 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP3_MOUSE
θ value	4.73814e-25 (rank : 6)	NC score	0.897120 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP2_HUMAN
θ value	7.56453e-23 (rank : 7)	NC score	0.861167 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP2_MOUSE
θ value	7.56453e-23 (rank : 8)	NC score	0.862003 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP4_HUMAN
θ value	7.32683e-18 (rank : 9)	NC score	0.855849 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	52	Shared Neighborhood Hits	34
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
θ value	7.32683e-18 (rank : 10)	NC score	0.854871 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP1_MOUSE
θ value	3.40345e-15 (rank : 11)	NC score	0.826219 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP1_HUMAN
θ value	1.29331e-14 (rank : 12)	NC score	0.836243 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

TICN2_HUMAN
θ value	8.40245e-06 (rank : 13)	NC score	0.446010 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_MOUSE
θ value	1.43324e-05 (rank : 14)	NC score	0.444311 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

NID2_HUMAN
θ value	0.00020696 (rank : 15)	NC score	0.187488 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	456	Shared Neighborhood Hits	38
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

TICN1_HUMAN
θ value	0.000602161 (rank : 16)	NC score	0.438823 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_MOUSE
θ value	0.000602161 (rank : 17)	NC score	0.438339 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	79	Shared Neighborhood Hits	35
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

NID1_HUMAN
θ value	0.00298849 (rank : 18)	NC score	0.186647 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	329	Shared Neighborhood Hits	37
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TICN3_HUMAN
θ value	0.00298849 (rank : 19)	NC score	0.415169 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

SMOC2_HUMAN
θ value	0.00509761 (rank : 20)	NC score	0.367457 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

THYG_HUMAN
θ value	0.00509761 (rank : 21)	NC score	0.231581 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	154	Shared Neighborhood Hits	33
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TICN3_MOUSE
θ value	0.00509761 (rank : 22)	NC score	0.408897 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

SMOC2_MOUSE
θ value	0.00665767 (rank : 23)	NC score	0.368461 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

THYG_MOUSE
θ value	0.00869519 (rank : 24)	NC score	0.219533 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	161	Shared Neighborhood Hits	33
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

NID2_MOUSE
θ value	0.0113563 (rank : 25)	NC score	0.186002 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	338	Shared Neighborhood Hits	37
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID1_MOUSE
θ value	0.0148317 (rank : 26)	NC score	0.175972 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	335	Shared Neighborhood Hits	36
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

HG2A_MOUSE
θ value	0.0431538 (rank : 27)	NC score	0.391066 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

SMOC1_MOUSE
θ value	0.0431538 (rank : 28)	NC score	0.344648 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	74	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

SRRM1_MOUSE
θ value	0.0431538 (rank : 29)	NC score	0.043020 (rank : 61)
Query Neighborhood Hits	53	Target Neighborhood Hits	966	Shared Neighborhood Hits	6
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SMOC1_HUMAN
θ value	0.0563607 (rank : 30)	NC score	0.346639 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

TACD2_HUMAN
θ value	0.0563607 (rank : 31)	NC score	0.287197 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

SRRM1_HUMAN
θ value	0.0736092 (rank : 32)	NC score	0.044007 (rank : 60)
Query Neighborhood Hits	53	Target Neighborhood Hits	690	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TACD1_HUMAN
θ value	0.0961366 (rank : 33)	NC score	0.310220 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	34	Shared Neighborhood Hits	31
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

HG2A_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.347354 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

HTRA1_MOUSE
θ value	0.21417 (rank : 35)	NC score	0.206947 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	140	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

CJ095_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.070533 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

FBN1_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.037753 (rank : 62)
Query Neighborhood Hits	53	Target Neighborhood Hits	557	Shared Neighborhood Hits	11
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

MELPH_MOUSE
θ value	0.62314 (rank : 38)	NC score	0.032184 (rank : 65)
Query Neighborhood Hits	53	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

HTRA1_HUMAN
θ value	0.813845 (rank : 39)	NC score	0.206824 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	155	Shared Neighborhood Hits	22
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

ESM1_HUMAN
θ value	1.38821 (rank : 40)	NC score	0.184950 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FBN1_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.036561 (rank : 64)
Query Neighborhood Hits	53	Target Neighborhood Hits	563	Shared Neighborhood Hits	11
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN3_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.037213 (rank : 63)
Query Neighborhood Hits	53	Target Neighborhood Hits	543	Shared Neighborhood Hits	13
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

IBP7_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.146969 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	230	Shared Neighborhood Hits	14
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

IBP7_HUMAN
θ value	1.81305 (rank : 44)	NC score	0.146849 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	220	Shared Neighborhood Hits	15
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

MEGF6_HUMAN
θ value	1.81305 (rank : 45)	NC score	0.030003 (rank : 67)
Query Neighborhood Hits	53	Target Neighborhood Hits	671	Shared Neighborhood Hits	18
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TCAL3_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.015978 (rank : 71)
Query Neighborhood Hits	53	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

SMAD6_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.014241 (rank : 72)
Query Neighborhood Hits	53	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	O43541, O43654, Q15799, Q9UKZ3	Gene names	SMAD6, MADH6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (hSMAD6).

STAB1_HUMAN
θ value	3.0926 (rank : 48)	NC score	0.031707 (rank : 66)
Query Neighborhood Hits	53	Target Neighborhood Hits	546	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

ZN688_HUMAN
θ value	5.27518 (rank : 49)	NC score	-0.002540 (rank : 74)
Query Neighborhood Hits	53	Target Neighborhood Hits	873	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

SFRIP_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.017917 (rank : 69)
Query Neighborhood Hits	53	Target Neighborhood Hits	530	Shared Neighborhood Hits	5
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CRSP7_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.016524 (rank : 70)
Query Neighborhood Hits	53	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

PLXB3_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.004090 (rank : 73)
Query Neighborhood Hits	53	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

ZHANG_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.018629 (rank : 68)
Query Neighborhood Hits	53	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NS37	Gene names	ZF
Domain Architecture	No domain graphic available
Description	Host cell factor-binding transcription factor Zhangfei (HCF-binding transcription factor Zhangfei).

CRIM1_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.087697 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	362	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CTGF_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.064983 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	15
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CYR61_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.053745 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.053913 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	156	Shared Neighborhood Hits	18
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

ESM1_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.156031 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	107	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FSTL3_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.053765 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	162	Shared Neighborhood Hits	20
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.051690 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.052396 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	129	Shared Neighborhood Hits	17
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

HTRA3_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.093583 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.092675 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HTRA4_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.064824 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

KAZD1_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.127944 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	248	Shared Neighborhood Hits	27
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.132431 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	281	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

LCE4A_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.161831 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

NOV_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.060618 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

SPRC_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.071659 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.069579 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRL1_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.063853 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	231	Shared Neighborhood Hits	13
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SPRL1_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.057503 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

WISP2_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.101807 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	126	Shared Neighborhood Hits	19
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.073235 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

Hits sorted by NC score

IBP6_MOUSE
NC score	0.999962 (rank : 1)	θ value	9.28496e-122 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP6_HUMAN
NC score	0.982204 (rank : 2)	θ value	4.98072e-83 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP5_HUMAN
NC score	0.901383 (rank : 3)	θ value	9.8567e-31 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
NC score	0.900416 (rank : 4)	θ value	1.28732e-30 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP3_MOUSE
NC score	0.897120 (rank : 5)	θ value	4.73814e-25 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP3_HUMAN
NC score	0.894910 (rank : 6)	θ value	7.80994e-28 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP2_MOUSE
NC score	0.862003 (rank : 7)	θ value	7.56453e-23 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP2_HUMAN
NC score	0.861167 (rank : 8)	θ value	7.56453e-23 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP4_HUMAN
NC score	0.855849 (rank : 9)	θ value	7.32683e-18 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	52	Shared Neighborhood Hits	34
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
NC score	0.854871 (rank : 10)	θ value	7.32683e-18 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP1_HUMAN
NC score	0.836243 (rank : 11)	θ value	1.29331e-14 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP1_MOUSE
NC score	0.826219 (rank : 12)	θ value	3.40345e-15 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

TICN2_HUMAN
NC score	0.446010 (rank : 13)	θ value	8.40245e-06 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_MOUSE
NC score	0.444311 (rank : 14)	θ value	1.43324e-05 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN1_HUMAN
NC score	0.438823 (rank : 15)	θ value	0.000602161 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_MOUSE
NC score	0.438339 (rank : 16)	θ value	0.000602161 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	79	Shared Neighborhood Hits	35
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN3_HUMAN
NC score	0.415169 (rank : 17)	θ value	0.00298849 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_MOUSE
NC score	0.408897 (rank : 18)	θ value	0.00509761 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

HG2A_MOUSE
NC score	0.391066 (rank : 19)	θ value	0.0431538 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

SMOC2_MOUSE
NC score	0.368461 (rank : 20)	θ value	0.00665767 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC2_HUMAN
NC score	0.367457 (rank : 21)	θ value	0.00509761 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

HG2A_HUMAN
NC score	0.347354 (rank : 22)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

SMOC1_HUMAN
NC score	0.346639 (rank : 23)	θ value	0.0563607 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
NC score	0.344648 (rank : 24)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	74	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

TACD1_HUMAN
NC score	0.310220 (rank : 25)	θ value	0.0961366 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	34	Shared Neighborhood Hits	31
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

TACD2_HUMAN
NC score	0.287197 (rank : 26)	θ value	0.0563607 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

THYG_HUMAN
NC score	0.231581 (rank : 27)	θ value	0.00509761 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	154	Shared Neighborhood Hits	33
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

THYG_MOUSE
NC score	0.219533 (rank : 28)	θ value	0.00869519 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	161	Shared Neighborhood Hits	33
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

HTRA1_MOUSE
NC score	0.206947 (rank : 29)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	140	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

HTRA1_HUMAN
NC score	0.206824 (rank : 30)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	155	Shared Neighborhood Hits	22
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

NID2_HUMAN
NC score	0.187488 (rank : 31)	θ value	0.00020696 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	456	Shared Neighborhood Hits	38
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID1_HUMAN
NC score	0.186647 (rank : 32)	θ value	0.00298849 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	329	Shared Neighborhood Hits	37
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_MOUSE
NC score	0.186002 (rank : 33)	θ value	0.0113563 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	338	Shared Neighborhood Hits	37
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

ESM1_HUMAN
NC score	0.184950 (rank : 34)	θ value	1.38821 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

NID1_MOUSE
NC score	0.175972 (rank : 35)	θ value	0.0148317 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	335	Shared Neighborhood Hits	36
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LCE4A_HUMAN
NC score	0.161831 (rank : 36)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	53	Target Neighborhood Hits	26	Shared Neighborhood Hits	8
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

ESM1_MOUSE
NC score	0.156031 (rank : 37)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	107	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

IBP7_MOUSE
NC score	0.146969 (rank : 38)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	230	Shared Neighborhood Hits	14
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

IBP7_HUMAN
NC score	0.146849 (rank : 39)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	220	Shared Neighborhood Hits	15
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

KAZD1_MOUSE
NC score	0.132431 (rank : 40)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	53	Target Neighborhood Hits	281	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KAZD1_HUMAN
NC score	0.127944 (rank : 41)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	53	Target Neighborhood Hits	248	Shared Neighborhood Hits	27
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

WISP2_HUMAN
NC score	0.101807 (rank : 42)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	53	Target Neighborhood Hits	126	Shared Neighborhood Hits	19
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

HTRA3_HUMAN
NC score	0.093583 (rank : 43)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	53	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
NC score	0.092675 (rank : 44)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	53	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

CRIM1_HUMAN
NC score	0.087697 (rank : 45)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	362	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

WISP2_MOUSE
NC score	0.073235 (rank : 46)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	53	Target Neighborhood Hits	129	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

SPRC_HUMAN
NC score	0.071659 (rank : 47)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	53	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

CJ095_HUMAN
NC score	0.070533 (rank : 48)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H7T3	Gene names	C10orf95
Domain Architecture	No domain graphic available
Description	Protein C10orf95.

SPRC_MOUSE
NC score	0.069579 (rank : 49)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	53	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

CTGF_HUMAN
NC score	0.064983 (rank : 50)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	15
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

HTRA4_HUMAN
NC score	0.064824 (rank : 51)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	53	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

SPRL1_HUMAN
NC score	0.063853 (rank : 52)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	53	Target Neighborhood Hits	231	Shared Neighborhood Hits	13
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

NOV_HUMAN
NC score	0.060618 (rank : 53)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

SPRL1_MOUSE
NC score	0.057503 (rank : 54)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	53	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CYR61_MOUSE
NC score	0.053913 (rank : 55)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	156	Shared Neighborhood Hits	18
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

FSTL3_HUMAN
NC score	0.053765 (rank : 56)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	162	Shared Neighborhood Hits	20
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

CYR61_HUMAN
NC score	0.053745 (rank : 57)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

FST_HUMAN
NC score	0.052396 (rank : 58)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	53	Target Neighborhood Hits	129	Shared Neighborhood Hits	17
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FSTL3_MOUSE
NC score	0.051690 (rank : 59)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	53	Target Neighborhood Hits	152	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

SRRM1_HUMAN
NC score	0.044007 (rank : 60)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	690	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
NC score	0.043020 (rank : 61)	θ value	0.0431538 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	966	Shared Neighborhood Hits	6
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

FBN1_HUMAN
NC score	0.037753 (rank : 62)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	557	Shared Neighborhood Hits	11
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN3_HUMAN
NC score	0.037213 (rank : 63)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	543	Shared Neighborhood Hits	13
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN1_MOUSE
NC score	0.036561 (rank : 64)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	563	Shared Neighborhood Hits	11
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

MELPH_MOUSE
NC score	0.032184 (rank : 65)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	Q91V27, Q99N53	Gene names	Mlph, Ln, Slac2a
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Leaden protein) (Synaptotagmin-like protein 2a) (Slac2-a) (Slp homolog lacking C2 domains a).

STAB1_HUMAN
NC score	0.031707 (rank : 66)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	546	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

MEGF6_HUMAN
NC score	0.030003 (rank : 67)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	671	Shared Neighborhood Hits	18
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

ZHANG_HUMAN
NC score	0.018629 (rank : 68)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NS37	Gene names	ZF
Domain Architecture	No domain graphic available
Description	Host cell factor-binding transcription factor Zhangfei (HCF-binding transcription factor Zhangfei).

SFRIP_HUMAN
NC score	0.017917 (rank : 69)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	530	Shared Neighborhood Hits	5
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

CRSP7_HUMAN
NC score	0.016524 (rank : 70)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

TCAL3_HUMAN
NC score	0.015978 (rank : 71)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

SMAD6_HUMAN
NC score	0.014241 (rank : 72)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	O43541, O43654, Q15799, Q9UKZ3	Gene names	SMAD6, MADH6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (hSMAD6).

PLXB3_HUMAN
NC score	0.004090 (rank : 73)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

ZN688_HUMAN
NC score	-0.002540 (rank : 74)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	873	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.