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Network neighborhood for query Sequence : TDRD3_HUMAN

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TDRD3_HUMAN
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TDRD3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.

TDRD3_MOUSE
θ value	0 (rank : 2)	NC score	0.980100 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q91W18, Q8BZW6	Gene names	Tdrd3
Domain Architecture
Description	Tudor domain-containing protein 3.

RMI1_HUMAN
θ value	1.06045e-08 (rank : 3)	NC score	0.357747 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9A7, Q5SQG8, Q5SQG9, Q6P1Q4, Q6PI89, Q7Z6L6	Gene names	RMI1, C9orf76
Domain Architecture	No domain graphic available
Description	Protein RMI1 homolog.

SPF30_HUMAN
θ value	1.99992e-07 (rank : 4)	NC score	0.409881 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	O75940	Gene names	SMNDC1, SMNR, SPF30
Domain Architecture
Description	Survival of motor neuron-related-splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain- containing protein 1).

SPF30_MOUSE
θ value	3.41135e-07 (rank : 5)	NC score	0.406057 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGT7, Q4QQL0	Gene names	Smndc1, Smnr, Spf30
Domain Architecture
Description	Survival of motor neuron-related-splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain- containing protein 1).

RMI1_MOUSE
θ value	5.81887e-07 (rank : 6)	NC score	0.341262 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D4G9, Q8C560, Q8CI20	Gene names	Rmi1
Domain Architecture	No domain graphic available
Description	Protein RMI1 homolog.

SMN_HUMAN
θ value	0.000461057 (rank : 7)	NC score	0.313007 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

SMN_MOUSE
θ value	0.000461057 (rank : 8)	NC score	0.308621 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	P97801, O09092	Gene names	Smn1, Smn
Domain Architecture
Description	Survival motor neuron protein.

TDRD1_MOUSE
θ value	0.00134147 (rank : 9)	NC score	0.192023 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MV1	Gene names	Tdrd1
Domain Architecture
Description	Tudor domain-containing protein 1.

TDRD1_HUMAN
θ value	0.00228821 (rank : 10)	NC score	0.183457 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BXT4, Q9H7B3	Gene names	TDRD1
Domain Architecture
Description	Tudor domain-containing protein 1.

NIPBL_HUMAN
θ value	0.00298849 (rank : 11)	NC score	0.099272 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	1311	Shared Neighborhood Hits	42
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

FOXGA_HUMAN
θ value	0.0113563 (rank : 12)	NC score	0.030501 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

TDRD6_MOUSE
θ value	0.0252991 (rank : 13)	NC score	0.151390 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

CHD1_MOUSE
θ value	0.0961366 (rank : 14)	NC score	0.044798 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	266	Shared Neighborhood Hits	18
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

NPBL_MOUSE
θ value	0.125558 (rank : 15)	NC score	0.096931 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	1041	Shared Neighborhood Hits	38
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

UBDC1_MOUSE
θ value	0.125558 (rank : 16)	NC score	0.127095 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDI7, Q3TZH3	Gene names	Ubadc1, Kpc2
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated domain-containing protein 1 (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2).

CHD1_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.045273 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	337	Shared Neighborhood Hits	22
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

GNAS3_HUMAN
θ value	0.21417 (rank : 18)	NC score	0.107727 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

PPIG_HUMAN
θ value	0.21417 (rank : 19)	NC score	0.048275 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	670	Shared Neighborhood Hits	33
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TOPRS_HUMAN
θ value	0.21417 (rank : 20)	NC score	0.056388 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	286	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TXND2_MOUSE
θ value	0.21417 (rank : 21)	NC score	0.058487 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

FILA_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.062329 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	685	Shared Neighborhood Hits	31
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

RSRC1_MOUSE
θ value	0.365318 (rank : 23)	NC score	0.081270 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

ANR11_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.028685 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	1289	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

WDR46_MOUSE
θ value	0.47712 (rank : 25)	NC score	0.044984 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

DDX23_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.018696 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	486	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DMP1_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.057157 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	498	Shared Neighborhood Hits	20
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

NUB1_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.060081 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	P54729, Q8K3U0	Gene names	Nub1, Nyren18
Domain Architecture
Description	NEDD8 ultimate buster 1 (Protein BS4).

SRCH_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.062318 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

RPA1_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.026823 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

UBP5_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.049454 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.049473 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

GSLG1_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.030142 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q61543, Q9QZ40	Gene names	Glg1, Esl1, Mg160, Selel
Domain Architecture
Description	Golgi apparatus protein 1 precursor (Golgi sialoglycoprotein MG-160) (E-selectin ligand 1) (ESL-1) (Selel).

UBDC1_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.069321 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BSL1, O75500, Q9UMW7	Gene names	UBADC1, GBDR1, KPC2
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated domain-containing protein 1 (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2) (Glialblastoma cell differentiation-related protein 1).

UBP13_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.050438 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

RSF1_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.036350 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	539	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SFRS4_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.041976 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	406	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

BRD4_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.019931 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	851	Shared Neighborhood Hits	17
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

LC7L2_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.033033 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	244	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

TOP2A_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.019905 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

UBP53_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.029731 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

CABIN_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.024689 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	490	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CAC1B_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.010457 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	351	Shared Neighborhood Hits	7
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

IF3A_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.015938 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	875	Shared Neighborhood Hits	12
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

NUB1_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.043015 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5A7, O95422, Q8IX22, Q9BXR2	Gene names	NUB1, NYREN18
Domain Architecture
Description	NEDD8 ultimate buster 1 (NY-REN-18 antigen).

SPRL1_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.031142 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SRRM2_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.033650 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	1470	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TTLL7_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.018110 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZT98, Q5TAX8, Q5TAX9, Q6P990, Q86YS1, Q9H5U4	Gene names	TTLL7
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 7 (Protein NYD-SP30).

UBQL4_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.014315 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

AKAP1_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.046905 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AKAP1_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.045453 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

ELOA1_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.034548 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	388	Shared Neighborhood Hits	29
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

FRM4A_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.011143 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	108	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

SFRS4_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.036972 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	384	Shared Neighborhood Hits	16
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

TCPZ_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.014447 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPZ_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.014404 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

XPC_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.023662 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

AFF4_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.038614 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	611	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

CHD2_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.035214 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	360	Shared Neighborhood Hits	19
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

DCP1B_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.018779 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

IWS1_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.039224 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	1241	Shared Neighborhood Hits	36
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1210_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.028278 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

SFR11_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.053111 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	246	Shared Neighborhood Hits	19
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SON_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.016569 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	1568	Shared Neighborhood Hits	22
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SRRM1_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.029170 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	966	Shared Neighborhood Hits	24
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SYNPO_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.016035 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

TRDN_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.031507 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	542	Shared Neighborhood Hits	14
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

WWC1_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.011369 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	290	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

AFF4_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.038970 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	581	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

BCAR3_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.008306 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	127	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

CCNL1_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.025498 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	79	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

DEK_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.031353 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

MMP1_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.003900 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].

MYOZ2_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.013604 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPC6, O43415, Q9HB92	Gene names	MYOZ2, C4orf5
Domain Architecture	No domain graphic available
Description	Myozenin-2 (Calsarcin-1) (FATZ-related protein 2).

RBBP6_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.042701 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	1135	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

Hits sorted by NC score

TDRD3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q9H7E2, Q6P992	Gene names	TDRD3
Domain Architecture
Description	Tudor domain-containing protein 3.

TDRD3_MOUSE
NC score	0.980100 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	29	Shared Neighborhood Hits	16
SwissProt Accessions	Q91W18, Q8BZW6	Gene names	Tdrd3
Domain Architecture
Description	Tudor domain-containing protein 3.

SPF30_HUMAN
NC score	0.409881 (rank : 3)	θ value	1.99992e-07 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	O75940	Gene names	SMNDC1, SMNR, SPF30
Domain Architecture
Description	Survival of motor neuron-related-splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain- containing protein 1).

SPF30_MOUSE
NC score	0.406057 (rank : 4)	θ value	3.41135e-07 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BGT7, Q4QQL0	Gene names	Smndc1, Smnr, Spf30
Domain Architecture
Description	Survival of motor neuron-related-splicing factor 30 (SMN-related protein) (30 kDa splicing factor SMNrp) (Survival motor neuron domain- containing protein 1).

RMI1_HUMAN
NC score	0.357747 (rank : 5)	θ value	1.06045e-08 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9A7, Q5SQG8, Q5SQG9, Q6P1Q4, Q6PI89, Q7Z6L6	Gene names	RMI1, C9orf76
Domain Architecture	No domain graphic available
Description	Protein RMI1 homolog.

RMI1_MOUSE
NC score	0.341262 (rank : 6)	θ value	5.81887e-07 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D4G9, Q8C560, Q8CI20	Gene names	Rmi1
Domain Architecture	No domain graphic available
Description	Protein RMI1 homolog.

SMN_HUMAN
NC score	0.313007 (rank : 7)	θ value	0.000461057 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q16637, Q13119, Q96J51	Gene names	SMN1, SMN, SMNT
Domain Architecture
Description	Survival motor neuron protein (Component of gems 1) (Gemin-1).

SMN_MOUSE
NC score	0.308621 (rank : 8)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	29	Shared Neighborhood Hits	8
SwissProt Accessions	P97801, O09092	Gene names	Smn1, Smn
Domain Architecture
Description	Survival motor neuron protein.

TDRD1_MOUSE
NC score	0.192023 (rank : 9)	θ value	0.00134147 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q99MV1	Gene names	Tdrd1
Domain Architecture
Description	Tudor domain-containing protein 1.

TDRD1_HUMAN
NC score	0.183457 (rank : 10)	θ value	0.00228821 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BXT4, Q9H7B3	Gene names	TDRD1
Domain Architecture
Description	Tudor domain-containing protein 1.

TDRD6_MOUSE
NC score	0.151390 (rank : 11)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

UBDC1_MOUSE
NC score	0.127095 (rank : 12)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDI7, Q3TZH3	Gene names	Ubadc1, Kpc2
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated domain-containing protein 1 (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2).

GNAS3_HUMAN
NC score	0.107727 (rank : 13)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	O95467, O95417	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

NIPBL_HUMAN
NC score	0.099272 (rank : 14)	θ value	0.00298849 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	1311	Shared Neighborhood Hits	42
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
NC score	0.096931 (rank : 15)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	1041	Shared Neighborhood Hits	38
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RSRC1_MOUSE
NC score	0.081270 (rank : 16)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	93	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBU6, Q3TF06	Gene names	Rsrc1
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich coiled coil protein 1.

UBDC1_HUMAN
NC score	0.069321 (rank : 17)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	25	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BSL1, O75500, Q9UMW7	Gene names	UBADC1, GBDR1, KPC2
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated domain-containing protein 1 (E3 ubiquitin-protein ligase subunit KPC2) (Kip1 ubiquitination-promoting complex protein 2) (Glialblastoma cell differentiation-related protein 1).

FILA_HUMAN
NC score	0.062329 (rank : 18)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	685	Shared Neighborhood Hits	31
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

SRCH_HUMAN
NC score	0.062318 (rank : 19)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

NUB1_MOUSE
NC score	0.060081 (rank : 20)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	P54729, Q8K3U0	Gene names	Nub1, Nyren18
Domain Architecture
Description	NEDD8 ultimate buster 1 (Protein BS4).

TXND2_MOUSE
NC score	0.058487 (rank : 21)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

DMP1_MOUSE
NC score	0.057157 (rank : 22)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	498	Shared Neighborhood Hits	20
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

TOPRS_HUMAN
NC score	0.056388 (rank : 23)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	286	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

SFR11_HUMAN
NC score	0.053111 (rank : 24)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	246	Shared Neighborhood Hits	19
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

UBP13_HUMAN
NC score	0.050438 (rank : 25)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP5_MOUSE
NC score	0.049473 (rank : 26)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_HUMAN
NC score	0.049454 (rank : 27)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

PPIG_HUMAN
NC score	0.048275 (rank : 28)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	670	Shared Neighborhood Hits	33
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

AKAP1_HUMAN
NC score	0.046905 (rank : 29)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

AKAP1_MOUSE
NC score	0.045453 (rank : 30)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	O08715, O08714, P97488	Gene names	Akap1, Akap
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein) (S-AKAP).

CHD1_HUMAN
NC score	0.045273 (rank : 31)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	337	Shared Neighborhood Hits	22
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

WDR46_MOUSE
NC score	0.044984 (rank : 32)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0H1	Gene names	Wdr46, Bing4
Domain Architecture
Description	WD repeat protein 46 (WD repeat protein BING4).

CHD1_MOUSE
NC score	0.044798 (rank : 33)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	266	Shared Neighborhood Hits	18
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

NUB1_HUMAN
NC score	0.043015 (rank : 34)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5A7, O95422, Q8IX22, Q9BXR2	Gene names	NUB1, NYREN18
Domain Architecture
Description	NEDD8 ultimate buster 1 (NY-REN-18 antigen).

RBBP6_HUMAN
NC score	0.042701 (rank : 35)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	1135	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SFRS4_MOUSE
NC score	0.041976 (rank : 36)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	406	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

IWS1_HUMAN
NC score	0.039224 (rank : 37)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	1241	Shared Neighborhood Hits	36
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AFF4_MOUSE
NC score	0.038970 (rank : 38)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	581	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AFF4_HUMAN
NC score	0.038614 (rank : 39)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	611	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

SFRS4_HUMAN
NC score	0.036972 (rank : 40)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	384	Shared Neighborhood Hits	16
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

RSF1_HUMAN
NC score	0.036350 (rank : 41)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	539	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

CHD2_HUMAN
NC score	0.035214 (rank : 42)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	360	Shared Neighborhood Hits	19
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

ELOA1_HUMAN
NC score	0.034548 (rank : 43)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	388	Shared Neighborhood Hits	29
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

SRRM2_MOUSE
NC score	0.033650 (rank : 44)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	1470	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

LC7L2_MOUSE
NC score	0.033033 (rank : 45)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	244	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TNC4, Q99LM5, Q99PC3	Gene names	Luc7l2
Domain Architecture
Description	Putative RNA-binding protein Luc7-like 2 (CGI-74 homolog).

TRDN_HUMAN
NC score	0.031507 (rank : 46)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	542	Shared Neighborhood Hits	14
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

DEK_MOUSE
NC score	0.031353 (rank : 47)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

SPRL1_HUMAN
NC score	0.031142 (rank : 48)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	231	Shared Neighborhood Hits	12
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

FOXGA_HUMAN
NC score	0.030501 (rank : 49)	θ value	0.0113563 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

GSLG1_MOUSE
NC score	0.030142 (rank : 50)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q61543, Q9QZ40	Gene names	Glg1, Esl1, Mg160, Selel
Domain Architecture
Description	Golgi apparatus protein 1 precursor (Golgi sialoglycoprotein MG-160) (E-selectin ligand 1) (ESL-1) (Selel).

UBP53_MOUSE
NC score	0.029731 (rank : 51)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	188	Shared Neighborhood Hits	16
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

SRRM1_MOUSE
NC score	0.029170 (rank : 52)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	966	Shared Neighborhood Hits	24
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ANR11_HUMAN
NC score	0.028685 (rank : 53)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	1289	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

K1210_HUMAN
NC score	0.028278 (rank : 54)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

RPA1_MOUSE
NC score	0.026823 (rank : 55)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	O35134, Q7TSA9	Gene names	Polr1a, Rpa1, Rpo1-4
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

CCNL1_HUMAN
NC score	0.025498 (rank : 56)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	79	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CABIN_HUMAN
NC score	0.024689 (rank : 57)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	490	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

XPC_MOUSE
NC score	0.023662 (rank : 58)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	7
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

BRD4_HUMAN
NC score	0.019931 (rank : 59)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	851	Shared Neighborhood Hits	17
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

TOP2A_MOUSE
NC score	0.019905 (rank : 60)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

DCP1B_HUMAN
NC score	0.018779 (rank : 61)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

DDX23_HUMAN
NC score	0.018696 (rank : 62)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	486	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

TTLL7_HUMAN
NC score	0.018110 (rank : 63)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZT98, Q5TAX8, Q5TAX9, Q6P990, Q86YS1, Q9H5U4	Gene names	TTLL7
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 7 (Protein NYD-SP30).

SON_HUMAN
NC score	0.016569 (rank : 64)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	1568	Shared Neighborhood Hits	22
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SYNPO_MOUSE
NC score	0.016035 (rank : 65)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

IF3A_HUMAN
NC score	0.015938 (rank : 66)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	875	Shared Neighborhood Hits	12
SwissProt Accessions	Q14152, O00653	Gene names	EIF3S10, KIAA0139
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a).

TCPZ_HUMAN
NC score	0.014447 (rank : 67)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	P40227, Q75LP4, Q96S46	Gene names	CCT6A, CCT6, CCTZ
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1) (Tcp20) (HTR3) (Acute morphine dependence-related protein 2).

TCPZ_MOUSE
NC score	0.014404 (rank : 68)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	P80317	Gene names	Cct6a, Cct6, Cctz, Cctz1
Domain Architecture
Description	T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (CCT-zeta-1).

UBQL4_MOUSE
NC score	0.014315 (rank : 69)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

MYOZ2_HUMAN
NC score	0.013604 (rank : 70)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPC6, O43415, Q9HB92	Gene names	MYOZ2, C4orf5
Domain Architecture	No domain graphic available
Description	Myozenin-2 (Calsarcin-1) (FATZ-related protein 2).

WWC1_MOUSE
NC score	0.011369 (rank : 71)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	290	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

FRM4A_MOUSE
NC score	0.011143 (rank : 72)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	108	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

CAC1B_MOUSE
NC score	0.010457 (rank : 73)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	351	Shared Neighborhood Hits	7
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

BCAR3_MOUSE
NC score	0.008306 (rank : 74)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	127	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZK2, Q3TNC9, Q3UP10	Gene names	Bcar3, And34
Domain Architecture	No domain graphic available
Description	Breast cancer anti-estrogen resistance protein 3 (p130Cas-binding protein AND-34).

MMP1_HUMAN
NC score	0.003900 (rank : 75)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	P03956, P08156	Gene names	MMP1, CLG
Domain Architecture
Description	Interstitial collagenase precursor (EC 3.4.24.7) (Matrix metalloproteinase-1) (MMP-1) (Fibroblast collagenase) [Contains: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase].