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Network neighborhood for query Sequence : LEF1_HUMAN

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LEF1_HUMAN
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LEF1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	150	Target Neighborhood Hits	150	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
θ value	0 (rank : 2)	NC score	0.997231 (rank : 2)
Query Neighborhood Hits	150	Target Neighborhood Hits	161	Shared Neighborhood Hits	141
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

TF7L2_MOUSE
θ value	4.32305e-111 (rank : 3)	NC score	0.971259 (rank : 3)
Query Neighborhood Hits	150	Target Neighborhood Hits	95	Shared Neighborhood Hits	67
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TF7L2_HUMAN
θ value	7.14227e-106 (rank : 4)	NC score	0.963767 (rank : 4)
Query Neighborhood Hits	150	Target Neighborhood Hits	119	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L1_HUMAN
θ value	2.01746e-92 (rank : 5)	NC score	0.957551 (rank : 5)
Query Neighborhood Hits	150	Target Neighborhood Hits	129	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

TF7L1_MOUSE
θ value	4.96919e-91 (rank : 6)	NC score	0.956415 (rank : 6)
Query Neighborhood Hits	150	Target Neighborhood Hits	131	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

TCF7_MOUSE
θ value	9.41505e-74 (rank : 7)	NC score	0.930985 (rank : 8)
Query Neighborhood Hits	150	Target Neighborhood Hits	277	Shared Neighborhood Hits	87
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TCF7_HUMAN
θ value	6.32992e-62 (rank : 8)	NC score	0.937600 (rank : 7)
Query Neighborhood Hits	150	Target Neighborhood Hits	186	Shared Neighborhood Hits	79
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

CIC_HUMAN
θ value	5.62301e-10 (rank : 9)	NC score	0.527309 (rank : 50)
Query Neighborhood Hits	150	Target Neighborhood Hits	992	Shared Neighborhood Hits	107
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	5.62301e-10 (rank : 10)	NC score	0.554293 (rank : 49)
Query Neighborhood Hits	150	Target Neighborhood Hits	742	Shared Neighborhood Hits	98
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SOX6_HUMAN
θ value	1.63604e-09 (rank : 11)	NC score	0.584684 (rank : 25)
Query Neighborhood Hits	150	Target Neighborhood Hits	332	Shared Neighborhood Hits	78
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
θ value	1.63604e-09 (rank : 12)	NC score	0.584027 (rank : 26)
Query Neighborhood Hits	150	Target Neighborhood Hits	341	Shared Neighborhood Hits	80
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SOX5_HUMAN
θ value	1.80886e-08 (rank : 13)	NC score	0.579940 (rank : 29)
Query Neighborhood Hits	150	Target Neighborhood Hits	219	Shared Neighborhood Hits	77
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
θ value	1.80886e-08 (rank : 14)	NC score	0.581667 (rank : 27)
Query Neighborhood Hits	150	Target Neighborhood Hits	196	Shared Neighborhood Hits	76
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX30_HUMAN
θ value	2.36244e-08 (rank : 15)	NC score	0.605070 (rank : 11)
Query Neighborhood Hits	150	Target Neighborhood Hits	305	Shared Neighborhood Hits	88
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX30_MOUSE
θ value	2.36244e-08 (rank : 16)	NC score	0.606068 (rank : 9)
Query Neighborhood Hits	150	Target Neighborhood Hits	374	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SOX13_HUMAN
θ value	4.0297e-08 (rank : 17)	NC score	0.575117 (rank : 36)
Query Neighborhood Hits	150	Target Neighborhood Hits	464	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
θ value	4.0297e-08 (rank : 18)	NC score	0.571257 (rank : 37)
Query Neighborhood Hits	150	Target Neighborhood Hits	495	Shared Neighborhood Hits	93
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX7_HUMAN
θ value	1.53129e-07 (rank : 19)	NC score	0.593599 (rank : 15)
Query Neighborhood Hits	150	Target Neighborhood Hits	140	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX7_MOUSE
θ value	1.53129e-07 (rank : 20)	NC score	0.597534 (rank : 14)
Query Neighborhood Hits	150	Target Neighborhood Hits	105	Shared Neighborhood Hits	75
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SRY_MOUSE
θ value	7.59969e-07 (rank : 21)	NC score	0.593058 (rank : 16)
Query Neighborhood Hits	150	Target Neighborhood Hits	139	Shared Neighborhood Hits	75
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX2_HUMAN
θ value	9.92553e-07 (rank : 22)	NC score	0.586402 (rank : 20)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
θ value	9.92553e-07 (rank : 23)	NC score	0.586050 (rank : 21)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	75
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX8_HUMAN
θ value	9.92553e-07 (rank : 24)	NC score	0.581349 (rank : 28)
Query Neighborhood Hits	150	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX8_MOUSE
θ value	9.92553e-07 (rank : 25)	NC score	0.578047 (rank : 31)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX12_HUMAN
θ value	2.21117e-06 (rank : 26)	NC score	0.602293 (rank : 13)
Query Neighborhood Hits	150	Target Neighborhood Hits	111	Shared Neighborhood Hits	71
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX12_MOUSE
θ value	2.21117e-06 (rank : 27)	NC score	0.603747 (rank : 12)
Query Neighborhood Hits	150	Target Neighborhood Hits	98	Shared Neighborhood Hits	71
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX14_HUMAN
θ value	2.21117e-06 (rank : 28)	NC score	0.587959 (rank : 18)
Query Neighborhood Hits	150	Target Neighborhood Hits	102	Shared Neighborhood Hits	76
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_MOUSE
θ value	2.21117e-06 (rank : 29)	NC score	0.588035 (rank : 17)
Query Neighborhood Hits	150	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX11_HUMAN
θ value	2.88788e-06 (rank : 30)	NC score	0.587319 (rank : 19)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX11_MOUSE
θ value	2.88788e-06 (rank : 31)	NC score	0.585804 (rank : 22)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	74
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SOX21_HUMAN
θ value	3.77169e-06 (rank : 32)	NC score	0.585728 (rank : 23)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX21_MOUSE
θ value	3.77169e-06 (rank : 33)	NC score	0.585699 (rank : 24)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	74
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SRY_HUMAN
θ value	3.77169e-06 (rank : 34)	NC score	0.605206 (rank : 10)
Query Neighborhood Hits	150	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX17_HUMAN
θ value	8.40245e-06 (rank : 35)	NC score	0.575720 (rank : 34)
Query Neighborhood Hits	150	Target Neighborhood Hits	108	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX17_MOUSE
θ value	8.40245e-06 (rank : 36)	NC score	0.575438 (rank : 35)
Query Neighborhood Hits	150	Target Neighborhood Hits	223	Shared Neighborhood Hits	86
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX4_MOUSE
θ value	1.09739e-05 (rank : 37)	NC score	0.579049 (rank : 30)
Query Neighborhood Hits	150	Target Neighborhood Hits	108	Shared Neighborhood Hits	74
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX10_HUMAN
θ value	1.43324e-05 (rank : 38)	NC score	0.559922 (rank : 45)
Query Neighborhood Hits	150	Target Neighborhood Hits	122	Shared Neighborhood Hits	70
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX9_HUMAN
θ value	1.43324e-05 (rank : 39)	NC score	0.560619 (rank : 44)
Query Neighborhood Hits	150	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_MOUSE
θ value	1.43324e-05 (rank : 40)	NC score	0.561262 (rank : 43)
Query Neighborhood Hits	150	Target Neighborhood Hits	188	Shared Neighborhood Hits	80
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX10_MOUSE
θ value	1.87187e-05 (rank : 41)	NC score	0.557793 (rank : 47)
Query Neighborhood Hits	150	Target Neighborhood Hits	110	Shared Neighborhood Hits	70
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX1_HUMAN
θ value	1.87187e-05 (rank : 42)	NC score	0.569653 (rank : 38)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX1_MOUSE
θ value	1.87187e-05 (rank : 43)	NC score	0.569105 (rank : 40)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	75
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX4_HUMAN
θ value	1.87187e-05 (rank : 44)	NC score	0.577903 (rank : 32)
Query Neighborhood Hits	150	Target Neighborhood Hits	111	Shared Neighborhood Hits	75
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX18_MOUSE
θ value	3.19293e-05 (rank : 45)	NC score	0.576156 (rank : 33)
Query Neighborhood Hits	150	Target Neighborhood Hits	105	Shared Neighborhood Hits	74
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SOX15_MOUSE
θ value	5.44631e-05 (rank : 46)	NC score	0.566198 (rank : 41)
Query Neighborhood Hits	150	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

SOX3_HUMAN
θ value	5.44631e-05 (rank : 47)	NC score	0.555964 (rank : 48)
Query Neighborhood Hits	150	Target Neighborhood Hits	109	Shared Neighborhood Hits	75
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SOX3_MOUSE
θ value	5.44631e-05 (rank : 48)	NC score	0.559002 (rank : 46)
Query Neighborhood Hits	150	Target Neighborhood Hits	101	Shared Neighborhood Hits	75
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

SOX15_HUMAN
θ value	7.1131e-05 (rank : 49)	NC score	0.562293 (rank : 42)
Query Neighborhood Hits	150	Target Neighborhood Hits	134	Shared Neighborhood Hits	82
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX18_HUMAN
θ value	7.1131e-05 (rank : 50)	NC score	0.569386 (rank : 39)
Query Neighborhood Hits	150	Target Neighborhood Hits	106	Shared Neighborhood Hits	77
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

BBX_HUMAN
θ value	0.000270298 (rank : 51)	NC score	0.484139 (rank : 54)
Query Neighborhood Hits	150	Target Neighborhood Hits	167	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BBX_MOUSE
θ value	0.000270298 (rank : 52)	NC score	0.487445 (rank : 53)
Query Neighborhood Hits	150	Target Neighborhood Hits	152	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

HBP1_HUMAN
θ value	0.000461057 (rank : 53)	NC score	0.507406 (rank : 52)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_MOUSE
θ value	0.000461057 (rank : 54)	NC score	0.508913 (rank : 51)
Query Neighborhood Hits	150	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

ENAH_MOUSE
θ value	0.00509761 (rank : 55)	NC score	0.069688 (rank : 87)
Query Neighborhood Hits	150	Target Neighborhood Hits	919	Shared Neighborhood Hits	34
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ANX11_HUMAN
θ value	0.0148317 (rank : 56)	NC score	0.034493 (rank : 112)
Query Neighborhood Hits	150	Target Neighborhood Hits	192	Shared Neighborhood Hits	13
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

HM20A_HUMAN
θ value	0.0148317 (rank : 57)	NC score	0.356240 (rank : 57)
Query Neighborhood Hits	150	Target Neighborhood Hits	343	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	0.0148317 (rank : 58)	NC score	0.355349 (rank : 58)
Query Neighborhood Hits	150	Target Neighborhood Hits	348	Shared Neighborhood Hits	75
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

MEF2B_MOUSE
θ value	0.0148317 (rank : 59)	NC score	0.066142 (rank : 90)
Query Neighborhood Hits	150	Target Neighborhood Hits	218	Shared Neighborhood Hits	22
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

SF3A2_MOUSE
θ value	0.0148317 (rank : 60)	NC score	0.111594 (rank : 83)
Query Neighborhood Hits	150	Target Neighborhood Hits	247	Shared Neighborhood Hits	27
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

HXB3_HUMAN
θ value	0.0252991 (rank : 61)	NC score	0.031731 (rank : 113)
Query Neighborhood Hits	150	Target Neighborhood Hits	559	Shared Neighborhood Hits	32
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

HM20B_HUMAN
θ value	0.0330416 (rank : 62)	NC score	0.364272 (rank : 55)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

HM20B_MOUSE
θ value	0.0431538 (rank : 63)	NC score	0.360874 (rank : 56)
Query Neighborhood Hits	150	Target Neighborhood Hits	122	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

GCX1_HUMAN
θ value	0.0736092 (rank : 64)	NC score	0.151385 (rank : 78)
Query Neighborhood Hits	150	Target Neighborhood Hits	132	Shared Neighborhood Hits	47
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

HXB3_MOUSE
θ value	0.0736092 (rank : 65)	NC score	0.027214 (rank : 118)
Query Neighborhood Hits	150	Target Neighborhood Hits	493	Shared Neighborhood Hits	24
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

SF3A2_HUMAN
θ value	0.0961366 (rank : 66)	NC score	0.095937 (rank : 85)
Query Neighborhood Hits	150	Target Neighborhood Hits	263	Shared Neighborhood Hits	25
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

SSRP1_MOUSE
θ value	0.0961366 (rank : 67)	NC score	0.339519 (rank : 59)
Query Neighborhood Hits	150	Target Neighborhood Hits	193	Shared Neighborhood Hits	75
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

CN092_HUMAN
θ value	0.125558 (rank : 68)	NC score	0.182645 (rank : 73)
Query Neighborhood Hits	150	Target Neighborhood Hits	143	Shared Neighborhood Hits	60
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
θ value	0.125558 (rank : 69)	NC score	0.177645 (rank : 75)
Query Neighborhood Hits	150	Target Neighborhood Hits	206	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

HM2L1_HUMAN
θ value	0.125558 (rank : 70)	NC score	0.266570 (rank : 69)
Query Neighborhood Hits	150	Target Neighborhood Hits	130	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

GLIS1_MOUSE
θ value	0.163984 (rank : 71)	NC score	0.004065 (rank : 156)
Query Neighborhood Hits	150	Target Neighborhood Hits	751	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

4ET_MOUSE
θ value	0.21417 (rank : 72)	NC score	0.062516 (rank : 92)
Query Neighborhood Hits	150	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

MAGI2_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.019581 (rank : 134)
Query Neighborhood Hits	150	Target Neighborhood Hits	373	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

ARI1B_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.045202 (rank : 100)
Query Neighborhood Hits	150	Target Neighborhood Hits	567	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

SSRP1_HUMAN
θ value	0.279714 (rank : 75)	NC score	0.335652 (rank : 60)
Query Neighborhood Hits	150	Target Neighborhood Hits	187	Shared Neighborhood Hits	75
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

UBF1_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.301897 (rank : 61)
Query Neighborhood Hits	150	Target Neighborhood Hits	415	Shared Neighborhood Hits	78
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

ZIM10_HUMAN
θ value	0.279714 (rank : 77)	NC score	0.041092 (rank : 106)
Query Neighborhood Hits	150	Target Neighborhood Hits	577	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

RBM12_HUMAN
θ value	0.365318 (rank : 78)	NC score	0.046307 (rank : 98)
Query Neighborhood Hits	150	Target Neighborhood Hits	298	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

UBF1_MOUSE
θ value	0.47712 (rank : 79)	NC score	0.291611 (rank : 62)
Query Neighborhood Hits	150	Target Neighborhood Hits	419	Shared Neighborhood Hits	78
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

ZN207_HUMAN
θ value	0.47712 (rank : 80)	NC score	0.066583 (rank : 89)
Query Neighborhood Hits	150	Target Neighborhood Hits	326	Shared Neighborhood Hits	13
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ATN1_HUMAN
θ value	0.62314 (rank : 81)	NC score	0.067922 (rank : 88)
Query Neighborhood Hits	150	Target Neighborhood Hits	676	Shared Neighborhood Hits	35
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BAG4_HUMAN
θ value	0.62314 (rank : 82)	NC score	0.041027 (rank : 107)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

CNOT4_HUMAN
θ value	0.62314 (rank : 83)	NC score	0.047251 (rank : 97)
Query Neighborhood Hits	150	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

ITCH_MOUSE
θ value	0.62314 (rank : 84)	NC score	0.009623 (rank : 148)
Query Neighborhood Hits	150	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

PB1_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.193756 (rank : 72)
Query Neighborhood Hits	150	Target Neighborhood Hits	261	Shared Neighborhood Hits	79
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

4ET_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.057802 (rank : 94)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

ABI2_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.021792 (rank : 130)
Query Neighborhood Hits	150	Target Neighborhood Hits	350	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

CNOT4_MOUSE
θ value	0.813845 (rank : 88)	NC score	0.047907 (rank : 96)
Query Neighborhood Hits	150	Target Neighborhood Hits	277	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

HMGB1_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.269755 (rank : 68)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
θ value	0.813845 (rank : 90)	NC score	0.269825 (rank : 67)
Query Neighborhood Hits	150	Target Neighborhood Hits	123	Shared Neighborhood Hits	74
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

MILK1_MOUSE
θ value	0.813845 (rank : 91)	NC score	0.026924 (rank : 119)
Query Neighborhood Hits	150	Target Neighborhood Hits	788	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PMS1_HUMAN
θ value	0.813845 (rank : 92)	NC score	0.163781 (rank : 77)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	63
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

TFCP2_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.028606 (rank : 116)
Query Neighborhood Hits	150	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q12800, Q12801, Q9UD77	Gene names	TFCP2, LSF, SEF
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2 (Transcription factor LSF) (SAA3 enhancer factor).

TFCP2_MOUSE
θ value	0.813845 (rank : 94)	NC score	0.028616 (rank : 115)
Query Neighborhood Hits	150	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERA0, Q3UGJ4, Q8VC13	Gene names	Tcfcp2
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2.

MLL3_MOUSE
θ value	1.06291 (rank : 95)	NC score	0.040951 (rank : 108)
Query Neighborhood Hits	150	Target Neighborhood Hits	1399	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
θ value	1.38821 (rank : 96)	NC score	0.045777 (rank : 99)
Query Neighborhood Hits	150	Target Neighborhood Hits	1644	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYCD_HUMAN
θ value	1.38821 (rank : 97)	NC score	0.023871 (rank : 124)
Query Neighborhood Hits	150	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

PHLB2_HUMAN
θ value	1.38821 (rank : 98)	NC score	0.009808 (rank : 147)
Query Neighborhood Hits	150	Target Neighborhood Hits	964	Shared Neighborhood Hits	11
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

ST5_MOUSE
θ value	1.38821 (rank : 99)	NC score	0.020320 (rank : 133)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	8
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

HMGB2_HUMAN
θ value	1.81305 (rank : 100)	NC score	0.289451 (rank : 63)
Query Neighborhood Hits	150	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

IF4G3_HUMAN
θ value	1.81305 (rank : 101)	NC score	0.021993 (rank : 129)
Query Neighborhood Hits	150	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

PTN23_MOUSE
θ value	1.81305 (rank : 102)	NC score	0.023321 (rank : 126)
Query Neighborhood Hits	150	Target Neighborhood Hits	726	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SPT5H_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.044662 (rank : 102)
Query Neighborhood Hits	150	Target Neighborhood Hits	436	Shared Neighborhood Hits	27
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	1.81305 (rank : 104)	NC score	0.044791 (rank : 101)
Query Neighborhood Hits	150	Target Neighborhood Hits	437	Shared Neighborhood Hits	28
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

ABLM1_HUMAN
θ value	2.36792 (rank : 105)	NC score	0.018044 (rank : 135)
Query Neighborhood Hits	150	Target Neighborhood Hits	387	Shared Neighborhood Hits	11
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

ASPP1_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.017913 (rank : 136)
Query Neighborhood Hits	150	Target Neighborhood Hits	1244	Shared Neighborhood Hits	37
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

DIAP1_HUMAN
θ value	2.36792 (rank : 107)	NC score	0.030068 (rank : 114)
Query Neighborhood Hits	150	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

MBD6_HUMAN
θ value	2.36792 (rank : 108)	NC score	0.050055 (rank : 95)
Query Neighborhood Hits	150	Target Neighborhood Hits	349	Shared Neighborhood Hits	22
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

MYO15_HUMAN
θ value	2.36792 (rank : 109)	NC score	0.016799 (rank : 139)
Query Neighborhood Hits	150	Target Neighborhood Hits	671	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PRR13_HUMAN
θ value	2.36792 (rank : 110)	NC score	0.101520 (rank : 84)
Query Neighborhood Hits	150	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

RERE_HUMAN
θ value	2.36792 (rank : 111)	NC score	0.062408 (rank : 93)
Query Neighborhood Hits	150	Target Neighborhood Hits	779	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

BAT2_HUMAN
θ value	3.0926 (rank : 112)	NC score	0.044379 (rank : 103)
Query Neighborhood Hits	150	Target Neighborhood Hits	931	Shared Neighborhood Hits	40
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.044332 (rank : 104)
Query Neighborhood Hits	150	Target Neighborhood Hits	1008	Shared Neighborhood Hits	53
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

DMRT1_MOUSE
θ value	3.0926 (rank : 114)	NC score	0.022968 (rank : 127)
Query Neighborhood Hits	150	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ59, Q9QZ37, Q9QZA4	Gene names	Dmrt1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1.

EFS_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.024963 (rank : 122)
Query Neighborhood Hits	150	Target Neighborhood Hits	348	Shared Neighborhood Hits	17
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

ENAH_HUMAN
θ value	3.0926 (rank : 116)	NC score	0.026677 (rank : 120)
Query Neighborhood Hits	150	Target Neighborhood Hits	784	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

HMGB2_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.270488 (rank : 66)
Query Neighborhood Hits	150	Target Neighborhood Hits	111	Shared Neighborhood Hits	75
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

IRX2_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.007633 (rank : 152)
Query Neighborhood Hits	150	Target Neighborhood Hits	358	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

PCD15_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.004824 (rank : 154)
Query Neighborhood Hits	150	Target Neighborhood Hits	289	Shared Neighborhood Hits	10
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

RPB1_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.036459 (rank : 109)
Query Neighborhood Hits	150	Target Neighborhood Hits	362	Shared Neighborhood Hits	19
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	3.0926 (rank : 121)	NC score	0.036243 (rank : 111)
Query Neighborhood Hits	150	Target Neighborhood Hits	363	Shared Neighborhood Hits	18
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

AT11A_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.020345 (rank : 132)
Query Neighborhood Hits	150	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	P98196, Q5VXT2	Gene names	ATP11A, ATPIH, ATPIS, KIAA1021
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase class I type 11A) (ATPase IS).

MAP1B_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.010981 (rank : 145)
Query Neighborhood Hits	150	Target Neighborhood Hits	903	Shared Neighborhood Hits	15
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NELFA_MOUSE
θ value	4.03905 (rank : 124)	NC score	0.022700 (rank : 128)
Query Neighborhood Hits	150	Target Neighborhood Hits	195	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

SET1A_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.025403 (rank : 121)
Query Neighborhood Hits	150	Target Neighborhood Hits	690	Shared Neighborhood Hits	28
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SMCE1_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.182351 (rank : 74)
Query Neighborhood Hits	150	Target Neighborhood Hits	272	Shared Neighborhood Hits	62
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.171574 (rank : 76)
Query Neighborhood Hits	150	Target Neighborhood Hits	409	Shared Neighborhood Hits	65
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

BASP_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.024418 (rank : 123)
Query Neighborhood Hits	150	Target Neighborhood Hits	321	Shared Neighborhood Hits	7
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

DIP2C_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.008896 (rank : 149)
Query Neighborhood Hits	150	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2E4	Gene names	DIP2C, KIAA0934
Domain Architecture
Description	Disco-interacting protein 2 homolog C.

FIGN_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.012156 (rank : 142)
Query Neighborhood Hits	150	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

FOXGB_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.005141 (rank : 153)
Query Neighborhood Hits	150	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	P55315	Gene names	FOXG1B, FKHL1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1) (HFK1).

KIF12_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.004792 (rank : 155)
Query Neighborhood Hits	150	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	Q96FN5, Q5TBE0	Gene names	KIF12
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF12.

PRB4S_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.041789 (rank : 105)
Query Neighborhood Hits	150	Target Neighborhood Hits	330	Shared Neighborhood Hits	20
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

SMAD1_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.007950 (rank : 151)
Query Neighborhood Hits	150	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

TMBI1_MOUSE
θ value	5.27518 (rank : 135)	NC score	0.010379 (rank : 146)
Query Neighborhood Hits	150	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJZ3, Q8CH91, Q99KB6	Gene names	Tmbim1, Recs1
Domain Architecture
Description	Transmembrane BAX inhibitor motif-containing protein 1 (RECS1 protein) (Responsive to centrifugal force and shear stress gene 1 protein).

AT11A_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.016998 (rank : 138)
Query Neighborhood Hits	150	Target Neighborhood Hits	77	Shared Neighborhood Hits	10
SwissProt Accessions	P98197	Gene names	Atp11a
Domain Architecture
Description	Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase class I type 11A) (ATPase IS).

IF4G3_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.017803 (rank : 137)
Query Neighborhood Hits	150	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

MNT_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.023432 (rank : 125)
Query Neighborhood Hits	150	Target Neighborhood Hits	432	Shared Neighborhood Hits	22
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

RBM12_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.036449 (rank : 110)
Query Neighborhood Hits	150	Target Neighborhood Hits	313	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RERE_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.065002 (rank : 91)
Query Neighborhood Hits	150	Target Neighborhood Hits	785	Shared Neighborhood Hits	41
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

RUNX2_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.011273 (rank : 144)
Query Neighborhood Hits	150	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.013882 (rank : 141)
Query Neighborhood Hits	150	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

SGIP1_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.021042 (rank : 131)
Query Neighborhood Hits	150	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TFAM_MOUSE
θ value	6.88961 (rank : 144)	NC score	0.208443 (rank : 71)
Query Neighborhood Hits	150	Target Neighborhood Hits	93	Shared Neighborhood Hits	72
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

FIP1_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.014433 (rank : 140)
Query Neighborhood Hits	150	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

HNF3A_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.003516 (rank : 157)
Query Neighborhood Hits	150	Target Neighborhood Hits	140	Shared Neighborhood Hits	7
SwissProt Accessions	P35582, Q61108	Gene names	Foxa1, Hnf3a, Tcf-3a, Tcf3a
Domain Architecture
Description	Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1).

KCNA5_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.002653 (rank : 158)
Query Neighborhood Hits	150	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

LNP_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.008843 (rank : 150)
Query Neighborhood Hits	150	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

MYO15_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.011645 (rank : 143)
Query Neighborhood Hits	150	Target Neighborhood Hits	467	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SYN1_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.028033 (rank : 117)
Query Neighborhood Hits	150	Target Neighborhood Hits	419	Shared Neighborhood Hits	24
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

HMG1X_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.218006 (rank : 70)
Query Neighborhood Hits	150	Target Neighborhood Hits	97	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HMGB3_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.280530 (rank : 64)
Query Neighborhood Hits	150	Target Neighborhood Hits	86	Shared Neighborhood Hits	67
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.277949 (rank : 65)
Query Neighborhood Hits	150	Target Neighborhood Hits	88	Shared Neighborhood Hits	68
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

PRR13_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.083322 (rank : 86)
Query Neighborhood Hits	150	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SP100_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.122396 (rank : 82)
Query Neighborhood Hits	150	Target Neighborhood Hits	117	Shared Neighborhood Hits	62
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

TFAM_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.144263 (rank : 79)
Query Neighborhood Hits	150	Target Neighborhood Hits	156	Shared Neighborhood Hits	58
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

TOX_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.131128 (rank : 81)
Query Neighborhood Hits	150	Target Neighborhood Hits	106	Shared Neighborhood Hits	48
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.131356 (rank : 80)
Query Neighborhood Hits	150	Target Neighborhood Hits	95	Shared Neighborhood Hits	48
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

Hits sorted by NC score

LEF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	150	Target Neighborhood Hits	150	Shared Neighborhood Hits	150
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
NC score	0.997231 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	150	Target Neighborhood Hits	161	Shared Neighborhood Hits	141
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

TF7L2_MOUSE
NC score	0.971259 (rank : 3)	θ value	4.32305e-111 (rank : 3)
Query Neighborhood Hits	150	Target Neighborhood Hits	95	Shared Neighborhood Hits	67
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TF7L2_HUMAN
NC score	0.963767 (rank : 4)	θ value	7.14227e-106 (rank : 4)
Query Neighborhood Hits	150	Target Neighborhood Hits	119	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L1_HUMAN
NC score	0.957551 (rank : 5)	θ value	2.01746e-92 (rank : 5)
Query Neighborhood Hits	150	Target Neighborhood Hits	129	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

TF7L1_MOUSE
NC score	0.956415 (rank : 6)	θ value	4.96919e-91 (rank : 6)
Query Neighborhood Hits	150	Target Neighborhood Hits	131	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

TCF7_HUMAN
NC score	0.937600 (rank : 7)	θ value	6.32992e-62 (rank : 8)
Query Neighborhood Hits	150	Target Neighborhood Hits	186	Shared Neighborhood Hits	79
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TCF7_MOUSE
NC score	0.930985 (rank : 8)	θ value	9.41505e-74 (rank : 7)
Query Neighborhood Hits	150	Target Neighborhood Hits	277	Shared Neighborhood Hits	87
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

SOX30_MOUSE
NC score	0.606068 (rank : 9)	θ value	2.36244e-08 (rank : 16)
Query Neighborhood Hits	150	Target Neighborhood Hits	374	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SRY_HUMAN
NC score	0.605206 (rank : 10)	θ value	3.77169e-06 (rank : 34)
Query Neighborhood Hits	150	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX30_HUMAN
NC score	0.605070 (rank : 11)	θ value	2.36244e-08 (rank : 15)
Query Neighborhood Hits	150	Target Neighborhood Hits	305	Shared Neighborhood Hits	88
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX12_MOUSE
NC score	0.603747 (rank : 12)	θ value	2.21117e-06 (rank : 27)
Query Neighborhood Hits	150	Target Neighborhood Hits	98	Shared Neighborhood Hits	71
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX12_HUMAN
NC score	0.602293 (rank : 13)	θ value	2.21117e-06 (rank : 26)
Query Neighborhood Hits	150	Target Neighborhood Hits	111	Shared Neighborhood Hits	71
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX7_MOUSE
NC score	0.597534 (rank : 14)	θ value	1.53129e-07 (rank : 20)
Query Neighborhood Hits	150	Target Neighborhood Hits	105	Shared Neighborhood Hits	75
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SOX7_HUMAN
NC score	0.593599 (rank : 15)	θ value	1.53129e-07 (rank : 19)
Query Neighborhood Hits	150	Target Neighborhood Hits	140	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SRY_MOUSE
NC score	0.593058 (rank : 16)	θ value	7.59969e-07 (rank : 21)
Query Neighborhood Hits	150	Target Neighborhood Hits	139	Shared Neighborhood Hits	75
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX14_MOUSE
NC score	0.588035 (rank : 17)	θ value	2.21117e-06 (rank : 29)
Query Neighborhood Hits	150	Target Neighborhood Hits	100	Shared Neighborhood Hits	76
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_HUMAN
NC score	0.587959 (rank : 18)	θ value	2.21117e-06 (rank : 28)
Query Neighborhood Hits	150	Target Neighborhood Hits	102	Shared Neighborhood Hits	76
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX11_HUMAN
NC score	0.587319 (rank : 19)	θ value	2.88788e-06 (rank : 30)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX2_HUMAN
NC score	0.586402 (rank : 20)	θ value	9.92553e-07 (rank : 22)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	75
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
NC score	0.586050 (rank : 21)	θ value	9.92553e-07 (rank : 23)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	75
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX11_MOUSE
NC score	0.585804 (rank : 22)	θ value	2.88788e-06 (rank : 31)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	74
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SOX21_HUMAN
NC score	0.585728 (rank : 23)	θ value	3.77169e-06 (rank : 32)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX21_MOUSE
NC score	0.585699 (rank : 24)	θ value	3.77169e-06 (rank : 33)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	74
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SOX6_HUMAN
NC score	0.584684 (rank : 25)	θ value	1.63604e-09 (rank : 11)
Query Neighborhood Hits	150	Target Neighborhood Hits	332	Shared Neighborhood Hits	78
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
NC score	0.584027 (rank : 26)	θ value	1.63604e-09 (rank : 12)
Query Neighborhood Hits	150	Target Neighborhood Hits	341	Shared Neighborhood Hits	80
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

SOX5_MOUSE
NC score	0.581667 (rank : 27)	θ value	1.80886e-08 (rank : 14)
Query Neighborhood Hits	150	Target Neighborhood Hits	196	Shared Neighborhood Hits	76
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX8_HUMAN
NC score	0.581349 (rank : 28)	θ value	9.92553e-07 (rank : 24)
Query Neighborhood Hits	150	Target Neighborhood Hits	100	Shared Neighborhood Hits	73
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX5_HUMAN
NC score	0.579940 (rank : 29)	θ value	1.80886e-08 (rank : 13)
Query Neighborhood Hits	150	Target Neighborhood Hits	219	Shared Neighborhood Hits	77
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX4_MOUSE
NC score	0.579049 (rank : 30)	θ value	1.09739e-05 (rank : 37)
Query Neighborhood Hits	150	Target Neighborhood Hits	108	Shared Neighborhood Hits	74
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX8_MOUSE
NC score	0.578047 (rank : 31)	θ value	9.92553e-07 (rank : 25)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	72
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX4_HUMAN
NC score	0.577903 (rank : 32)	θ value	1.87187e-05 (rank : 44)
Query Neighborhood Hits	150	Target Neighborhood Hits	111	Shared Neighborhood Hits	75
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX18_MOUSE
NC score	0.576156 (rank : 33)	θ value	3.19293e-05 (rank : 45)
Query Neighborhood Hits	150	Target Neighborhood Hits	105	Shared Neighborhood Hits	74
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SOX17_HUMAN
NC score	0.575720 (rank : 34)	θ value	8.40245e-06 (rank : 35)
Query Neighborhood Hits	150	Target Neighborhood Hits	108	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX17_MOUSE
NC score	0.575438 (rank : 35)	θ value	8.40245e-06 (rank : 36)
Query Neighborhood Hits	150	Target Neighborhood Hits	223	Shared Neighborhood Hits	86
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX13_HUMAN
NC score	0.575117 (rank : 36)	θ value	4.0297e-08 (rank : 17)
Query Neighborhood Hits	150	Target Neighborhood Hits	464	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
NC score	0.571257 (rank : 37)	θ value	4.0297e-08 (rank : 18)
Query Neighborhood Hits	150	Target Neighborhood Hits	495	Shared Neighborhood Hits	93
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX1_HUMAN
NC score	0.569653 (rank : 38)	θ value	1.87187e-05 (rank : 42)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX18_HUMAN
NC score	0.569386 (rank : 39)	θ value	7.1131e-05 (rank : 50)
Query Neighborhood Hits	150	Target Neighborhood Hits	106	Shared Neighborhood Hits	77
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SOX1_MOUSE
NC score	0.569105 (rank : 40)	θ value	1.87187e-05 (rank : 43)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	75
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX15_MOUSE
NC score	0.566198 (rank : 41)	θ value	5.44631e-05 (rank : 46)
Query Neighborhood Hits	150	Target Neighborhood Hits	100	Shared Neighborhood Hits	78
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

SOX15_HUMAN
NC score	0.562293 (rank : 42)	θ value	7.1131e-05 (rank : 49)
Query Neighborhood Hits	150	Target Neighborhood Hits	134	Shared Neighborhood Hits	82
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX9_MOUSE
NC score	0.561262 (rank : 43)	θ value	1.43324e-05 (rank : 40)
Query Neighborhood Hits	150	Target Neighborhood Hits	188	Shared Neighborhood Hits	80
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_HUMAN
NC score	0.560619 (rank : 44)	θ value	1.43324e-05 (rank : 39)
Query Neighborhood Hits	150	Target Neighborhood Hits	210	Shared Neighborhood Hits	79
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX10_HUMAN
NC score	0.559922 (rank : 45)	θ value	1.43324e-05 (rank : 38)
Query Neighborhood Hits	150	Target Neighborhood Hits	122	Shared Neighborhood Hits	70
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX3_MOUSE
NC score	0.559002 (rank : 46)	θ value	5.44631e-05 (rank : 48)
Query Neighborhood Hits	150	Target Neighborhood Hits	101	Shared Neighborhood Hits	75
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

SOX10_MOUSE
NC score	0.557793 (rank : 47)	θ value	1.87187e-05 (rank : 41)
Query Neighborhood Hits	150	Target Neighborhood Hits	110	Shared Neighborhood Hits	70
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX3_HUMAN
NC score	0.555964 (rank : 48)	θ value	5.44631e-05 (rank : 47)
Query Neighborhood Hits	150	Target Neighborhood Hits	109	Shared Neighborhood Hits	75
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

CIC_MOUSE
NC score	0.554293 (rank : 49)	θ value	5.62301e-10 (rank : 10)
Query Neighborhood Hits	150	Target Neighborhood Hits	742	Shared Neighborhood Hits	98
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_HUMAN
NC score	0.527309 (rank : 50)	θ value	5.62301e-10 (rank : 9)
Query Neighborhood Hits	150	Target Neighborhood Hits	992	Shared Neighborhood Hits	107
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

HBP1_MOUSE
NC score	0.508913 (rank : 51)	θ value	0.000461057 (rank : 54)
Query Neighborhood Hits	150	Target Neighborhood Hits	86	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_HUMAN
NC score	0.507406 (rank : 52)	θ value	0.000461057 (rank : 53)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

BBX_MOUSE
NC score	0.487445 (rank : 53)	θ value	0.000270298 (rank : 52)
Query Neighborhood Hits	150	Target Neighborhood Hits	152	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BBX_HUMAN
NC score	0.484139 (rank : 54)	θ value	0.000270298 (rank : 51)
Query Neighborhood Hits	150	Target Neighborhood Hits	167	Shared Neighborhood Hits	74
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

HM20B_HUMAN
NC score	0.364272 (rank : 55)	θ value	0.0330416 (rank : 62)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	72
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

HM20B_MOUSE
NC score	0.360874 (rank : 56)	θ value	0.0431538 (rank : 63)
Query Neighborhood Hits	150	Target Neighborhood Hits	122	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

HM20A_HUMAN
NC score	0.356240 (rank : 57)	θ value	0.0148317 (rank : 57)
Query Neighborhood Hits	150	Target Neighborhood Hits	343	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
NC score	0.355349 (rank : 58)	θ value	0.0148317 (rank : 58)
Query Neighborhood Hits	150	Target Neighborhood Hits	348	Shared Neighborhood Hits	75
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

SSRP1_MOUSE
NC score	0.339519 (rank : 59)	θ value	0.0961366 (rank : 67)
Query Neighborhood Hits	150	Target Neighborhood Hits	193	Shared Neighborhood Hits	75
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

SSRP1_HUMAN
NC score	0.335652 (rank : 60)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	150	Target Neighborhood Hits	187	Shared Neighborhood Hits	75
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

UBF1_HUMAN
NC score	0.301897 (rank : 61)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	150	Target Neighborhood Hits	415	Shared Neighborhood Hits	78
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBF1_MOUSE
NC score	0.291611 (rank : 62)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	150	Target Neighborhood Hits	419	Shared Neighborhood Hits	78
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

HMGB2_HUMAN
NC score	0.289451 (rank : 63)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	150	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB3_HUMAN
NC score	0.280530 (rank : 64)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	150	Target Neighborhood Hits	86	Shared Neighborhood Hits	67
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_MOUSE
NC score	0.277949 (rank : 65)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	150	Target Neighborhood Hits	88	Shared Neighborhood Hits	68
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB2_MOUSE
NC score	0.270488 (rank : 66)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	150	Target Neighborhood Hits	111	Shared Neighborhood Hits	75
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB1_MOUSE
NC score	0.269825 (rank : 67)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	150	Target Neighborhood Hits	123	Shared Neighborhood Hits	74
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_HUMAN
NC score	0.269755 (rank : 68)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	74
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HM2L1_HUMAN
NC score	0.266570 (rank : 69)	θ value	0.125558 (rank : 70)
Query Neighborhood Hits	150	Target Neighborhood Hits	130	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

HMG1X_HUMAN
NC score	0.218006 (rank : 70)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	150	Target Neighborhood Hits	97	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

TFAM_MOUSE
NC score	0.208443 (rank : 71)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	150	Target Neighborhood Hits	93	Shared Neighborhood Hits	72
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

PB1_HUMAN
NC score	0.193756 (rank : 72)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	150	Target Neighborhood Hits	261	Shared Neighborhood Hits	79
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

CN092_HUMAN
NC score	0.182645 (rank : 73)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	150	Target Neighborhood Hits	143	Shared Neighborhood Hits	60
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

SMCE1_HUMAN
NC score	0.182351 (rank : 74)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	150	Target Neighborhood Hits	272	Shared Neighborhood Hits	62
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

CN092_MOUSE
NC score	0.177645 (rank : 75)	θ value	0.125558 (rank : 69)
Query Neighborhood Hits	150	Target Neighborhood Hits	206	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

SMCE1_MOUSE
NC score	0.171574 (rank : 76)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	150	Target Neighborhood Hits	409	Shared Neighborhood Hits	65
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

PMS1_HUMAN
NC score	0.163781 (rank : 77)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	63
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

GCX1_HUMAN
NC score	0.151385 (rank : 78)	θ value	0.0736092 (rank : 64)
Query Neighborhood Hits	150	Target Neighborhood Hits	132	Shared Neighborhood Hits	47
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

TFAM_HUMAN
NC score	0.144263 (rank : 79)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	150	Target Neighborhood Hits	156	Shared Neighborhood Hits	58
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

TOX_MOUSE
NC score	0.131356 (rank : 80)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	150	Target Neighborhood Hits	95	Shared Neighborhood Hits	48
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_HUMAN
NC score	0.131128 (rank : 81)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	150	Target Neighborhood Hits	106	Shared Neighborhood Hits	48
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

SP100_HUMAN
NC score	0.122396 (rank : 82)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	150	Target Neighborhood Hits	117	Shared Neighborhood Hits	62
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

SF3A2_MOUSE
NC score	0.111594 (rank : 83)	θ value	0.0148317 (rank : 60)
Query Neighborhood Hits	150	Target Neighborhood Hits	247	Shared Neighborhood Hits	27
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

PRR13_HUMAN
NC score	0.101520 (rank : 84)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	150	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

SF3A2_HUMAN
NC score	0.095937 (rank : 85)	θ value	0.0961366 (rank : 66)
Query Neighborhood Hits	150	Target Neighborhood Hits	263	Shared Neighborhood Hits	25
SwissProt Accessions	Q15428, O75245	Gene names	SF3A2, SAP62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

PRR13_MOUSE
NC score	0.083322 (rank : 86)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	150	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

ENAH_MOUSE
NC score	0.069688 (rank : 87)	θ value	0.00509761 (rank : 55)
Query Neighborhood Hits	150	Target Neighborhood Hits	919	Shared Neighborhood Hits	34
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ATN1_HUMAN
NC score	0.067922 (rank : 88)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	150	Target Neighborhood Hits	676	Shared Neighborhood Hits	35
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

ZN207_HUMAN
NC score	0.066583 (rank : 89)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	150	Target Neighborhood Hits	326	Shared Neighborhood Hits	13
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

MEF2B_MOUSE
NC score	0.066142 (rank : 90)	θ value	0.0148317 (rank : 59)
Query Neighborhood Hits	150	Target Neighborhood Hits	218	Shared Neighborhood Hits	22
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

RERE_MOUSE
NC score	0.065002 (rank : 91)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	150	Target Neighborhood Hits	785	Shared Neighborhood Hits	41
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

4ET_MOUSE
NC score	0.062516 (rank : 92)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	150	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

RERE_HUMAN
NC score	0.062408 (rank : 93)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	150	Target Neighborhood Hits	779	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

4ET_HUMAN
NC score	0.057802 (rank : 94)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRA8, Q8NCF2, Q9H708	Gene names	EIF4ENIF1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

MBD6_HUMAN
NC score	0.050055 (rank : 95)	θ value	2.36792 (rank : 108)
Query Neighborhood Hits	150	Target Neighborhood Hits	349	Shared Neighborhood Hits	22
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

CNOT4_MOUSE
NC score	0.047907 (rank : 96)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	150	Target Neighborhood Hits	277	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

CNOT4_HUMAN
NC score	0.047251 (rank : 97)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	150	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	O95628, O95339, O95627, Q8IYM7, Q8NCL0, Q9NPQ1, Q9NZN6	Gene names	CNOT4, NOT4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

RBM12_HUMAN
NC score	0.046307 (rank : 98)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	150	Target Neighborhood Hits	298	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

MLL3_HUMAN
NC score	0.045777 (rank : 99)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	150	Target Neighborhood Hits	1644	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ARI1B_HUMAN
NC score	0.045202 (rank : 100)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	150	Target Neighborhood Hits	567	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

SPT5H_MOUSE
NC score	0.044791 (rank : 101)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	150	Target Neighborhood Hits	437	Shared Neighborhood Hits	28
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

SPT5H_HUMAN
NC score	0.044662 (rank : 102)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	150	Target Neighborhood Hits	436	Shared Neighborhood Hits	27
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

BAT2_HUMAN
NC score	0.044379 (rank : 103)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	150	Target Neighborhood Hits	931	Shared Neighborhood Hits	40
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_HUMAN
NC score	0.044332 (rank : 104)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	150	Target Neighborhood Hits	1008	Shared Neighborhood Hits	53
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

PRB4S_HUMAN
NC score	0.041789 (rank : 105)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	150	Target Neighborhood Hits	330	Shared Neighborhood Hits	20
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

ZIM10_HUMAN
NC score	0.041092 (rank : 106)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	150	Target Neighborhood Hits	577	Shared Neighborhood Hits	38
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

BAG4_HUMAN
NC score	0.041027 (rank : 107)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	O95429, O95818	Gene names	BAG4, SODD
Domain Architecture
Description	BAG family molecular chaperone regulator 4 (BCL2-associated athanogene 4) (BAG-4) (Silencer of death domains).

MLL3_MOUSE
NC score	0.040951 (rank : 108)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	150	Target Neighborhood Hits	1399	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RPB1_HUMAN
NC score	0.036459 (rank : 109)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	150	Target Neighborhood Hits	362	Shared Neighborhood Hits	19
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RBM12_MOUSE
NC score	0.036449 (rank : 110)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	150	Target Neighborhood Hits	313	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RPB1_MOUSE
NC score	0.036243 (rank : 111)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	150	Target Neighborhood Hits	363	Shared Neighborhood Hits	18
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ANX11_HUMAN
NC score	0.034493 (rank : 112)	θ value	0.0148317 (rank : 56)
Query Neighborhood Hits	150	Target Neighborhood Hits	192	Shared Neighborhood Hits	13
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

HXB3_HUMAN
NC score	0.031731 (rank : 113)	θ value	0.0252991 (rank : 61)
Query Neighborhood Hits	150	Target Neighborhood Hits	559	Shared Neighborhood Hits	32
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

DIAP1_HUMAN
NC score	0.030068 (rank : 114)	θ value	2.36792 (rank : 107)
Query Neighborhood Hits	150	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

TFCP2_MOUSE
NC score	0.028616 (rank : 115)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	150	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERA0, Q3UGJ4, Q8VC13	Gene names	Tcfcp2
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2.

TFCP2_HUMAN
NC score	0.028606 (rank : 116)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	150	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q12800, Q12801, Q9UD77	Gene names	TFCP2, LSF, SEF
Domain Architecture	No domain graphic available
Description	Alpha-globin transcription factor CP2 (Transcription factor LSF) (SAA3 enhancer factor).

SYN1_HUMAN
NC score	0.028033 (rank : 117)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	150	Target Neighborhood Hits	419	Shared Neighborhood Hits	24
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

HXB3_MOUSE
NC score	0.027214 (rank : 118)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	150	Target Neighborhood Hits	493	Shared Neighborhood Hits	24
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

MILK1_MOUSE
NC score	0.026924 (rank : 119)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	150	Target Neighborhood Hits	788	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

ENAH_HUMAN
NC score	0.026677 (rank : 120)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	150	Target Neighborhood Hits	784	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

SET1A_HUMAN
NC score	0.025403 (rank : 121)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	150	Target Neighborhood Hits	690	Shared Neighborhood Hits	28
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

EFS_HUMAN
NC score	0.024963 (rank : 122)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	150	Target Neighborhood Hits	348	Shared Neighborhood Hits	17
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

BASP_HUMAN
NC score	0.024418 (rank : 123)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	150	Target Neighborhood Hits	321	Shared Neighborhood Hits	7
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MYCD_HUMAN
NC score	0.023871 (rank : 124)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	150	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

MNT_MOUSE
NC score	0.023432 (rank : 125)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	150	Target Neighborhood Hits	432	Shared Neighborhood Hits	22
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PTN23_MOUSE
NC score	0.023321 (rank : 126)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	150	Target Neighborhood Hits	726	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

DMRT1_MOUSE
NC score	0.022968 (rank : 127)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	150	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ59, Q9QZ37, Q9QZA4	Gene names	Dmrt1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1.

NELFA_MOUSE
NC score	0.022700 (rank : 128)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	150	Target Neighborhood Hits	195	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

IF4G3_HUMAN
NC score	0.021993 (rank : 129)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	150	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

ABI2_HUMAN
NC score	0.021792 (rank : 130)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	150	Target Neighborhood Hits	350	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

SGIP1_MOUSE
NC score	0.021042 (rank : 131)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	150	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

AT11A_HUMAN
NC score	0.020345 (rank : 132)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	150	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	P98196, Q5VXT2	Gene names	ATP11A, ATPIH, ATPIS, KIAA1021
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase class I type 11A) (ATPase IS).

ST5_MOUSE
NC score	0.020320 (rank : 133)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	8
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

MAGI2_HUMAN
NC score	0.019581 (rank : 134)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	150	Target Neighborhood Hits	373	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

ABLM1_HUMAN
NC score	0.018044 (rank : 135)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	150	Target Neighborhood Hits	387	Shared Neighborhood Hits	11
SwissProt Accessions	O14639, Q15039, Q68CQ9, Q9BUP1	Gene names	ABLIM1, ABLIM, KIAA0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1) (Actin-binding double-zinc-finger protein) (LIMAB1) (Limatin).

ASPP1_MOUSE
NC score	0.017913 (rank : 136)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	150	Target Neighborhood Hits	1244	Shared Neighborhood Hits	37
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

IF4G3_MOUSE
NC score	0.017803 (rank : 137)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	150	Target Neighborhood Hits	279	Shared Neighborhood Hits	12
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

AT11A_MOUSE
NC score	0.016998 (rank : 138)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	150	Target Neighborhood Hits	77	Shared Neighborhood Hits	10
SwissProt Accessions	P98197	Gene names	Atp11a
Domain Architecture
Description	Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase class I type 11A) (ATPase IS).

MYO15_HUMAN
NC score	0.016799 (rank : 139)	θ value	2.36792 (rank : 109)
Query Neighborhood Hits	150	Target Neighborhood Hits	671	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

FIP1_MOUSE
NC score	0.014433 (rank : 140)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	150	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D824, Q8BWX7, Q99LH0, Q9DBB2	Gene names	Fip1l1
Domain Architecture	No domain graphic available
Description	Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1).

RUNX2_MOUSE
NC score	0.013882 (rank : 141)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	150	Target Neighborhood Hits	119	Shared Neighborhood Hits	10
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

FIGN_MOUSE
NC score	0.012156 (rank : 142)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	150	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

MYO15_MOUSE
NC score	0.011645 (rank : 143)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	150	Target Neighborhood Hits	467	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RUNX2_HUMAN
NC score	0.011273 (rank : 144)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	150	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

MAP1B_HUMAN
NC score	0.010981 (rank : 145)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	150	Target Neighborhood Hits	903	Shared Neighborhood Hits	15
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

TMBI1_MOUSE
NC score	0.010379 (rank : 146)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	150	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJZ3, Q8CH91, Q99KB6	Gene names	Tmbim1, Recs1
Domain Architecture
Description	Transmembrane BAX inhibitor motif-containing protein 1 (RECS1 protein) (Responsive to centrifugal force and shear stress gene 1 protein).

PHLB2_HUMAN
NC score	0.009808 (rank : 147)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	150	Target Neighborhood Hits	964	Shared Neighborhood Hits	11
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

ITCH_MOUSE
NC score	0.009623 (rank : 148)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	150	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

DIP2C_HUMAN
NC score	0.008896 (rank : 149)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	150	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2E4	Gene names	DIP2C, KIAA0934
Domain Architecture
Description	Disco-interacting protein 2 homolog C.

LNP_HUMAN
NC score	0.008843 (rank : 150)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	150	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C0E8, Q2M2V8, Q2YD99, Q658W8, Q8N5V9, Q96MS5	Gene names	LNP, KIAA1715
Domain Architecture	No domain graphic available
Description	Protein lunapark.

SMAD1_MOUSE
NC score	0.007950 (rank : 151)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	150	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

IRX2_HUMAN
NC score	0.007633 (rank : 152)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	150	Target Neighborhood Hits	358	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

FOXGB_HUMAN
NC score	0.005141 (rank : 153)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	150	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	P55315	Gene names	FOXG1B, FKHL1
Domain Architecture
Description	Forkhead box protein G1B (Forkhead-related protein FKHL1) (Transcription factor BF-1) (Brain factor 1) (BF1) (HFK1).

PCD15_HUMAN
NC score	0.004824 (rank : 154)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	150	Target Neighborhood Hits	289	Shared Neighborhood Hits	10
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

KIF12_HUMAN
NC score	0.004792 (rank : 155)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	150	Target Neighborhood Hits	148	Shared Neighborhood Hits	4
SwissProt Accessions	Q96FN5, Q5TBE0	Gene names	KIF12
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF12.

GLIS1_MOUSE
NC score	0.004065 (rank : 156)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	150	Target Neighborhood Hits	751	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

HNF3A_MOUSE
NC score	0.003516 (rank : 157)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	150	Target Neighborhood Hits	140	Shared Neighborhood Hits	7
SwissProt Accessions	P35582, Q61108	Gene names	Foxa1, Hnf3a, Tcf-3a, Tcf3a
Domain Architecture
Description	Hepatocyte nuclear factor 3-alpha (HNF-3A) (Forkhead box protein A1).

KCNA5_HUMAN
NC score	0.002653 (rank : 158)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	150	Target Neighborhood Hits	124	Shared Neighborhood Hits	4
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).