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Network neighborhood for query Sequence : SP100_HUMAN

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SP100_HUMAN
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SP100_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	117
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

LY10_HUMAN
θ value	1.14825e-79 (rank : 2)	NC score	0.494843 (rank : 17)
Query Neighborhood Hits	117	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

HMGB1_HUMAN
θ value	1.84173e-61 (rank : 3)	NC score	0.800974 (rank : 4)
Query Neighborhood Hits	117	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_MOUSE
θ value	1.84173e-61 (rank : 4)	NC score	0.801255 (rank : 3)
Query Neighborhood Hits	117	Target Neighborhood Hits	123	Shared Neighborhood Hits	70
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMG1X_HUMAN
θ value	2.25136e-59 (rank : 5)	NC score	0.813606 (rank : 2)
Query Neighborhood Hits	117	Target Neighborhood Hits	97	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HMGB2_HUMAN
θ value	3.0428e-56 (rank : 6)	NC score	0.788434 (rank : 6)
Query Neighborhood Hits	117	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_MOUSE
θ value	5.73848e-55 (rank : 7)	NC score	0.791188 (rank : 5)
Query Neighborhood Hits	117	Target Neighborhood Hits	111	Shared Neighborhood Hits	70
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

SP100_MOUSE
θ value	9.81109e-47 (rank : 8)	NC score	0.572754 (rank : 9)
Query Neighborhood Hits	117	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

HMGB3_MOUSE
θ value	3.37985e-39 (rank : 9)	NC score	0.768137 (rank : 7)
Query Neighborhood Hits	117	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_HUMAN
θ value	5.76516e-39 (rank : 10)	NC score	0.765557 (rank : 8)
Query Neighborhood Hits	117	Target Neighborhood Hits	86	Shared Neighborhood Hits	69
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

S100R_MOUSE
θ value	4.57862e-28 (rank : 11)	NC score	0.553151 (rank : 10)
Query Neighborhood Hits	117	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

SP110_HUMAN
θ value	2.12685e-25 (rank : 12)	NC score	0.456081 (rank : 20)
Query Neighborhood Hits	117	Target Neighborhood Hits	141	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

IPR1_MOUSE
θ value	7.56453e-23 (rank : 13)	NC score	0.519737 (rank : 13)
Query Neighborhood Hits	117	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

SSRP1_HUMAN
θ value	7.84624e-12 (rank : 14)	NC score	0.545753 (rank : 11)
Query Neighborhood Hits	117	Target Neighborhood Hits	187	Shared Neighborhood Hits	72
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

DEAF1_HUMAN
θ value	6.64225e-11 (rank : 15)	NC score	0.311579 (rank : 32)
Query Neighborhood Hits	117	Target Neighborhood Hits	67	Shared Neighborhood Hits	15
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

DEAF1_MOUSE
θ value	6.64225e-11 (rank : 16)	NC score	0.310011 (rank : 33)
Query Neighborhood Hits	117	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

SSRP1_MOUSE
θ value	1.133e-10 (rank : 17)	NC score	0.535322 (rank : 12)
Query Neighborhood Hits	117	Target Neighborhood Hits	193	Shared Neighborhood Hits	71
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

HM20B_MOUSE
θ value	4.76016e-09 (rank : 18)	NC score	0.510639 (rank : 14)
Query Neighborhood Hits	117	Target Neighborhood Hits	122	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

HM20B_HUMAN
θ value	1.99992e-07 (rank : 19)	NC score	0.493442 (rank : 18)
Query Neighborhood Hits	117	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

HM20A_HUMAN
θ value	2.61198e-07 (rank : 20)	NC score	0.450675 (rank : 21)
Query Neighborhood Hits	117	Target Neighborhood Hits	343	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
θ value	2.61198e-07 (rank : 21)	NC score	0.448928 (rank : 22)
Query Neighborhood Hits	117	Target Neighborhood Hits	348	Shared Neighborhood Hits	70
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

TFAM_MOUSE
θ value	5.81887e-07 (rank : 22)	NC score	0.496718 (rank : 16)
Query Neighborhood Hits	117	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

HM2L1_HUMAN
θ value	2.21117e-06 (rank : 23)	NC score	0.498060 (rank : 15)
Query Neighborhood Hits	117	Target Neighborhood Hits	130	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

UBF1_MOUSE
θ value	6.43352e-06 (rank : 24)	NC score	0.380479 (rank : 28)
Query Neighborhood Hits	117	Target Neighborhood Hits	419	Shared Neighborhood Hits	72
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

UBF1_HUMAN
θ value	8.40245e-06 (rank : 25)	NC score	0.387550 (rank : 27)
Query Neighborhood Hits	117	Target Neighborhood Hits	415	Shared Neighborhood Hits	72
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

CN092_HUMAN
θ value	1.09739e-05 (rank : 26)	NC score	0.425006 (rank : 23)
Query Neighborhood Hits	117	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
θ value	1.09739e-05 (rank : 27)	NC score	0.416972 (rank : 24)
Query Neighborhood Hits	117	Target Neighborhood Hits	206	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

TFAM_HUMAN
θ value	1.43324e-05 (rank : 28)	NC score	0.468291 (rank : 19)
Query Neighborhood Hits	117	Target Neighborhood Hits	156	Shared Neighborhood Hits	63
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

BBX_MOUSE
θ value	9.29e-05 (rank : 29)	NC score	0.345761 (rank : 30)
Query Neighborhood Hits	117	Target Neighborhood Hits	152	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BBX_HUMAN
θ value	0.000121331 (rank : 30)	NC score	0.343717 (rank : 31)
Query Neighborhood Hits	117	Target Neighborhood Hits	167	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

GMEB1_MOUSE
θ value	0.00020696 (rank : 31)	NC score	0.205503 (rank : 82)
Query Neighborhood Hits	117	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JL60	Gene names	Gmeb1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1).

GMEB1_HUMAN
θ value	0.000270298 (rank : 32)	NC score	0.204962 (rank : 83)
Query Neighborhood Hits	117	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y692, Q9NWH1, Q9UKD0	Gene names	GMEB1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (Parvovirus initiation factor p96) (PIF p96) (DNA-binding protein p96PIF).

TOX_MOUSE
θ value	0.000786445 (rank : 33)	NC score	0.415993 (rank : 25)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

GMEB2_HUMAN
θ value	0.00102713 (rank : 34)	NC score	0.201013 (rank : 85)
Query Neighborhood Hits	117	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

GMEB2_MOUSE
θ value	0.00102713 (rank : 35)	NC score	0.201246 (rank : 84)
Query Neighborhood Hits	117	Target Neighborhood Hits	64	Shared Neighborhood Hits	10
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

TOX_HUMAN
θ value	0.00102713 (rank : 36)	NC score	0.411744 (rank : 26)
Query Neighborhood Hits	117	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

SOX8_HUMAN
θ value	0.00390308 (rank : 37)	NC score	0.306579 (rank : 34)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	63
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

GCX1_HUMAN
θ value	0.00509761 (rank : 38)	NC score	0.367070 (rank : 29)
Query Neighborhood Hits	117	Target Neighborhood Hits	132	Shared Neighborhood Hits	47
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

SOX8_MOUSE
θ value	0.00509761 (rank : 39)	NC score	0.306513 (rank : 35)
Query Neighborhood Hits	117	Target Neighborhood Hits	96	Shared Neighborhood Hits	63
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX10_HUMAN
θ value	0.00869519 (rank : 40)	NC score	0.286389 (rank : 47)
Query Neighborhood Hits	117	Target Neighborhood Hits	122	Shared Neighborhood Hits	59
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX10_MOUSE
θ value	0.00869519 (rank : 41)	NC score	0.286747 (rank : 46)
Query Neighborhood Hits	117	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX2_HUMAN
θ value	0.00869519 (rank : 42)	NC score	0.297547 (rank : 37)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_MOUSE
θ value	0.00869519 (rank : 43)	NC score	0.297663 (rank : 36)
Query Neighborhood Hits	117	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX9_HUMAN
θ value	0.0113563 (rank : 44)	NC score	0.292783 (rank : 43)
Query Neighborhood Hits	117	Target Neighborhood Hits	210	Shared Neighborhood Hits	64
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_MOUSE
θ value	0.0113563 (rank : 45)	NC score	0.293685 (rank : 42)
Query Neighborhood Hits	117	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX18_HUMAN
θ value	0.0148317 (rank : 46)	NC score	0.295906 (rank : 38)
Query Neighborhood Hits	117	Target Neighborhood Hits	106	Shared Neighborhood Hits	64
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

AIRE_HUMAN
θ value	0.0330416 (rank : 47)	NC score	0.115129 (rank : 91)
Query Neighborhood Hits	117	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	0.0563607 (rank : 48)	NC score	0.117907 (rank : 90)
Query Neighborhood Hits	117	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

HBP1_HUMAN
θ value	0.0563607 (rank : 49)	NC score	0.271450 (rank : 62)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	61
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

HBP1_MOUSE
θ value	0.0563607 (rank : 50)	NC score	0.270170 (rank : 65)
Query Neighborhood Hits	117	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

SOX14_HUMAN
θ value	0.0563607 (rank : 51)	NC score	0.294105 (rank : 40)
Query Neighborhood Hits	117	Target Neighborhood Hits	102	Shared Neighborhood Hits	68
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_MOUSE
θ value	0.0563607 (rank : 52)	NC score	0.294100 (rank : 41)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	68
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

PMS1_HUMAN
θ value	0.125558 (rank : 53)	NC score	0.278390 (rank : 54)
Query Neighborhood Hits	117	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

SRY_HUMAN
θ value	0.125558 (rank : 54)	NC score	0.285402 (rank : 49)
Query Neighborhood Hits	117	Target Neighborhood Hits	83	Shared Neighborhood Hits	68
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

CIC_HUMAN
θ value	0.163984 (rank : 55)	NC score	0.242309 (rank : 74)
Query Neighborhood Hits	117	Target Neighborhood Hits	992	Shared Neighborhood Hits	70
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	0.163984 (rank : 56)	NC score	0.256035 (rank : 71)
Query Neighborhood Hits	117	Target Neighborhood Hits	742	Shared Neighborhood Hits	66
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SRY_MOUSE
θ value	0.163984 (rank : 57)	NC score	0.273990 (rank : 59)
Query Neighborhood Hits	117	Target Neighborhood Hits	139	Shared Neighborhood Hits	69
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

FGD6_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.014788 (rank : 113)
Query Neighborhood Hits	117	Target Neighborhood Hits	237	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

SOX30_HUMAN
θ value	0.21417 (rank : 59)	NC score	0.272326 (rank : 60)
Query Neighborhood Hits	117	Target Neighborhood Hits	305	Shared Neighborhood Hits	67
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX30_MOUSE
θ value	0.21417 (rank : 60)	NC score	0.274092 (rank : 58)
Query Neighborhood Hits	117	Target Neighborhood Hits	374	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

ATRX_MOUSE
θ value	0.279714 (rank : 61)	NC score	0.037496 (rank : 101)
Query Neighborhood Hits	117	Target Neighborhood Hits	682	Shared Neighborhood Hits	21
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

DIP2A_HUMAN
θ value	0.365318 (rank : 62)	NC score	0.025441 (rank : 103)
Query Neighborhood Hits	117	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

SOX12_HUMAN
θ value	0.365318 (rank : 63)	NC score	0.286831 (rank : 45)
Query Neighborhood Hits	117	Target Neighborhood Hits	111	Shared Neighborhood Hits	63
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX12_MOUSE
θ value	0.365318 (rank : 64)	NC score	0.285982 (rank : 48)
Query Neighborhood Hits	117	Target Neighborhood Hits	98	Shared Neighborhood Hits	63
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SOX18_MOUSE
θ value	0.365318 (rank : 65)	NC score	0.278433 (rank : 53)
Query Neighborhood Hits	117	Target Neighborhood Hits	105	Shared Neighborhood Hits	63
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

SOX1_HUMAN
θ value	0.365318 (rank : 66)	NC score	0.276355 (rank : 55)
Query Neighborhood Hits	117	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX1_MOUSE
θ value	0.365318 (rank : 67)	NC score	0.275889 (rank : 57)
Query Neighborhood Hits	117	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX4_HUMAN
θ value	0.365318 (rank : 68)	NC score	0.276199 (rank : 56)
Query Neighborhood Hits	117	Target Neighborhood Hits	111	Shared Neighborhood Hits	67
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX4_MOUSE
θ value	0.47712 (rank : 69)	NC score	0.279003 (rank : 52)
Query Neighborhood Hits	117	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX13_HUMAN
θ value	0.62314 (rank : 70)	NC score	0.239009 (rank : 79)
Query Neighborhood Hits	117	Target Neighborhood Hits	464	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX13_MOUSE
θ value	0.62314 (rank : 71)	NC score	0.239684 (rank : 78)
Query Neighborhood Hits	117	Target Neighborhood Hits	495	Shared Neighborhood Hits	70
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX21_HUMAN
θ value	0.62314 (rank : 72)	NC score	0.282222 (rank : 50)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX21_MOUSE
θ value	0.62314 (rank : 73)	NC score	0.282215 (rank : 51)
Query Neighborhood Hits	117	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SOX3_HUMAN
θ value	0.62314 (rank : 74)	NC score	0.270219 (rank : 64)
Query Neighborhood Hits	117	Target Neighborhood Hits	109	Shared Neighborhood Hits	67
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

SOX3_MOUSE
θ value	0.62314 (rank : 75)	NC score	0.271894 (rank : 61)
Query Neighborhood Hits	117	Target Neighborhood Hits	101	Shared Neighborhood Hits	67
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

SOX6_HUMAN
θ value	0.62314 (rank : 76)	NC score	0.241398 (rank : 75)
Query Neighborhood Hits	117	Target Neighborhood Hits	332	Shared Neighborhood Hits	71
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
θ value	0.62314 (rank : 77)	NC score	0.241322 (rank : 76)
Query Neighborhood Hits	117	Target Neighborhood Hits	341	Shared Neighborhood Hits	71
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

STK10_HUMAN
θ value	0.62314 (rank : 78)	NC score	0.000572 (rank : 131)
Query Neighborhood Hits	117	Target Neighborhood Hits	1921	Shared Neighborhood Hits	21
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

ETV7_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.014142 (rank : 115)
Query Neighborhood Hits	117	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y603, Q9NZ65, Q9NZ66, Q9NZ68, Q9NZR8, Q9UNJ7, Q9Y5K4, Q9Y604	Gene names	ETV7, TEL2, TELB, TREF
Domain Architecture
Description	Transcription factor ETV7 (Transcription factor Tel-2) (ETS-related protein Tel2) (Tel-related Ets factor).

SH3G2_MOUSE
θ value	1.38821 (rank : 80)	NC score	0.015551 (rank : 111)
Query Neighborhood Hits	117	Target Neighborhood Hits	319	Shared Neighborhood Hits	8
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SMCE1_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.269192 (rank : 66)
Query Neighborhood Hits	117	Target Neighborhood Hits	272	Shared Neighborhood Hits	64
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SMCE1_MOUSE
θ value	1.38821 (rank : 82)	NC score	0.254040 (rank : 73)
Query Neighborhood Hits	117	Target Neighborhood Hits	409	Shared Neighborhood Hits	65
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

MYH10_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.006707 (rank : 124)
Query Neighborhood Hits	117	Target Neighborhood Hits	1620	Shared Neighborhood Hits	22
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	1.81305 (rank : 84)	NC score	0.006300 (rank : 125)
Query Neighborhood Hits	117	Target Neighborhood Hits	1612	Shared Neighborhood Hits	22
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SH3G2_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.014854 (rank : 112)
Query Neighborhood Hits	117	Target Neighborhood Hits	324	Shared Neighborhood Hits	8
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

SOX15_MOUSE
θ value	1.81305 (rank : 86)	NC score	0.288389 (rank : 44)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	68
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

BAZ1A_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.024263 (rank : 104)
Query Neighborhood Hits	117	Target Neighborhood Hits	693	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

MEPD_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.019090 (rank : 108)
Query Neighborhood Hits	117	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P52888, Q9UCB3	Gene names	THOP1
Domain Architecture
Description	Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78).

PB1_HUMAN
θ value	2.36792 (rank : 89)	NC score	0.241198 (rank : 77)
Query Neighborhood Hits	117	Target Neighborhood Hits	261	Shared Neighborhood Hits	69
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

SOX15_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.294347 (rank : 39)
Query Neighborhood Hits	117	Target Neighborhood Hits	134	Shared Neighborhood Hits	68
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

CG024_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.027461 (rank : 102)
Query Neighborhood Hits	117	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7X8, Q3URJ2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C7orf24 homolog.

CJ068_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.018451 (rank : 109)
Query Neighborhood Hits	117	Target Neighborhood Hits	316	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

KIF4A_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.004597 (rank : 126)
Query Neighborhood Hits	117	Target Neighborhood Hits	1159	Shared Neighborhood Hits	16
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

SRGP2_MOUSE
θ value	3.0926 (rank : 94)	NC score	0.010558 (rank : 118)
Query Neighborhood Hits	117	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

CLC1A_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.008243 (rank : 121)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWY2, Q7TPX7, Q8BMH5	Gene names	Clec1a
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 1 member A.

IL1R1_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.006885 (rank : 122)
Query Neighborhood Hits	117	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

P66A_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.014493 (rank : 114)
Query Neighborhood Hits	117	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q86YP4, Q7L3J2, Q96F28, Q9NPU2, Q9NXS1	Gene names	GATAD2A
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A).

VGFR1_MOUSE
θ value	4.03905 (rank : 98)	NC score	-0.003196 (rank : 134)
Query Neighborhood Hits	117	Target Neighborhood Hits	1118	Shared Neighborhood Hits	4
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

WDHD1_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.038924 (rank : 100)
Query Neighborhood Hits	117	Target Neighborhood Hits	342	Shared Neighborhood Hits	17
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

BLM_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.006812 (rank : 123)
Query Neighborhood Hits	117	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

MLL3_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.020579 (rank : 107)
Query Neighborhood Hits	117	Target Neighborhood Hits	1399	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PLCB3_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.015830 (rank : 110)
Query Neighborhood Hits	117	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

REPS1_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.009783 (rank : 119)
Query Neighborhood Hits	117	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RN169_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.013306 (rank : 116)
Query Neighborhood Hits	117	Target Neighborhood Hits	203	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

SRGP2_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.009396 (rank : 120)
Query Neighborhood Hits	117	Target Neighborhood Hits	331	Shared Neighborhood Hits	9
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

GCC2_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.002503 (rank : 130)
Query Neighborhood Hits	117	Target Neighborhood Hits	1558	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

NIPBL_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.023130 (rank : 105)
Query Neighborhood Hits	117	Target Neighborhood Hits	1311	Shared Neighborhood Hits	29
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PDE3A_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.004543 (rank : 127)
Query Neighborhood Hits	117	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

RBP24_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.002548 (rank : 129)
Query Neighborhood Hits	117	Target Neighborhood Hits	1559	Shared Neighborhood Hits	19
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

ZN174_HUMAN
θ value	6.88961 (rank : 110)	NC score	-0.004528 (rank : 135)
Query Neighborhood Hits	117	Target Neighborhood Hits	744	Shared Neighborhood Hits	2
SwissProt Accessions	Q15697, Q9BQ34	Gene names	ZNF174, ZSCAN8
Domain Architecture
Description	Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8).

1B47_HUMAN
θ value	8.99809 (rank : 111)	NC score	-0.001215 (rank : 133)
Query Neighborhood Hits	117	Target Neighborhood Hits	211	Shared Neighborhood Hits	2
SwissProt Accessions	P30485, O19555, O77933, Q95392, Q9GIL3	Gene names	HLA-B, HLAB
Domain Architecture
Description	HLA class I histocompatibility antigen, B-47 alpha chain precursor (MHC class I antigen B*47) (Bw-47).

CG024_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.020614 (rank : 106)
Query Neighborhood Hits	117	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	O75223	Gene names	C7orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C7orf24.

NKX61_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.000216 (rank : 132)
Query Neighborhood Hits	117	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

SOX11_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.268280 (rank : 67)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	66
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX11_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.266592 (rank : 68)
Query Neighborhood Hits	117	Target Neighborhood Hits	96	Shared Neighborhood Hits	66
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SPAG1_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.004286 (rank : 128)
Query Neighborhood Hits	117	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

SYCP2_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.013094 (rank : 117)
Query Neighborhood Hits	117	Target Neighborhood Hits	230	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

LEF1_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.122396 (rank : 88)
Query Neighborhood Hits	117	Target Neighborhood Hits	150	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.122241 (rank : 89)
Query Neighborhood Hits	117	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

PKCB1_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.050032 (rank : 99)
Query Neighborhood Hits	117	Target Neighborhood Hits	488	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

SOX17_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.255265 (rank : 72)
Query Neighborhood Hits	117	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SOX17_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.258219 (rank : 70)
Query Neighborhood Hits	117	Target Neighborhood Hits	223	Shared Neighborhood Hits	65
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

SOX5_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.226175 (rank : 81)
Query Neighborhood Hits	117	Target Neighborhood Hits	219	Shared Neighborhood Hits	67
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.227023 (rank : 80)
Query Neighborhood Hits	117	Target Neighborhood Hits	196	Shared Neighborhood Hits	67
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX7_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.266493 (rank : 69)
Query Neighborhood Hits	117	Target Neighborhood Hits	140	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX7_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.270416 (rank : 63)
Query Neighborhood Hits	117	Target Neighborhood Hits	105	Shared Neighborhood Hits	67
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

TCF7_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.131389 (rank : 86)
Query Neighborhood Hits	117	Target Neighborhood Hits	186	Shared Neighborhood Hits	57
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TCF7_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.127192 (rank : 87)
Query Neighborhood Hits	117	Target Neighborhood Hits	277	Shared Neighborhood Hits	55
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TF7L1_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.104760 (rank : 92)
Query Neighborhood Hits	117	Target Neighborhood Hits	129	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

TF7L1_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.104213 (rank : 95)
Query Neighborhood Hits	117	Target Neighborhood Hits	131	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

TF7L2_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.104754 (rank : 93)
Query Neighborhood Hits	117	Target Neighborhood Hits	119	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L2_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.104402 (rank : 94)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	52
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TIF1A_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.050210 (rank : 98)
Query Neighborhood Hits	117	Target Neighborhood Hits	307	Shared Neighborhood Hits	8
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRI66_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.054370 (rank : 96)
Query Neighborhood Hits	117	Target Neighborhood Hits	479	Shared Neighborhood Hits	15
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.052857 (rank : 97)
Query Neighborhood Hits	117	Target Neighborhood Hits	491	Shared Neighborhood Hits	19
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

Hits sorted by NC score

SP100_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	117	Target Neighborhood Hits	117	Shared Neighborhood Hits	117
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

HMG1X_HUMAN
NC score	0.813606 (rank : 2)	θ value	2.25136e-59 (rank : 5)
Query Neighborhood Hits	117	Target Neighborhood Hits	97	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UGV6	Gene names	HMG1L10
Domain Architecture
Description	High mobility group protein 1-like 10 (HMG-1L10).

HMGB1_MOUSE
NC score	0.801255 (rank : 3)	θ value	1.84173e-61 (rank : 4)
Query Neighborhood Hits	117	Target Neighborhood Hits	123	Shared Neighborhood Hits	70
SwissProt Accessions	P63158, P07155, P27109, P27428	Gene names	Hmgb1, Hmg-1, Hmg1
Domain Architecture	No domain graphic available
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB1_HUMAN
NC score	0.800974 (rank : 4)	θ value	1.84173e-61 (rank : 3)
Query Neighborhood Hits	117	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	P09429, Q6IBE1	Gene names	HMGB1, HMG1
Domain Architecture
Description	High mobility group protein B1 (High mobility group protein 1) (HMG- 1).

HMGB2_MOUSE
NC score	0.791188 (rank : 5)	θ value	5.73848e-55 (rank : 7)
Query Neighborhood Hits	117	Target Neighborhood Hits	111	Shared Neighborhood Hits	70
SwissProt Accessions	P30681, Q3UXT1, Q9EQD5	Gene names	Hmgb2, Hmg2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB2_HUMAN
NC score	0.788434 (rank : 6)	θ value	3.0428e-56 (rank : 6)
Query Neighborhood Hits	117	Target Neighborhood Hits	114	Shared Neighborhood Hits	70
SwissProt Accessions	P26583	Gene names	HMGB2, HMG2
Domain Architecture
Description	High mobility group protein B2 (High mobility group protein 2) (HMG- 2).

HMGB3_MOUSE
NC score	0.768137 (rank : 7)	θ value	3.37985e-39 (rank : 9)
Query Neighborhood Hits	117	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	O54879	Gene names	Hmgb3, Hmg2a, Hmg4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

HMGB3_HUMAN
NC score	0.765557 (rank : 8)	θ value	5.76516e-39 (rank : 10)
Query Neighborhood Hits	117	Target Neighborhood Hits	86	Shared Neighborhood Hits	69
SwissProt Accessions	O15347, O95556, Q6NS40	Gene names	HMGB3, HMG2A, HMG4
Domain Architecture
Description	High mobility group protein B3 (High mobility group protein 4) (HMG-4) (High mobility group protein 2a) (HMG-2a).

SP100_MOUSE
NC score	0.572754 (rank : 9)	θ value	9.81109e-47 (rank : 8)
Query Neighborhood Hits	117	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	O35892, O35897, O88392, O88395	Gene names	Sp100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein).

S100R_MOUSE
NC score	0.553151 (rank : 10)	θ value	4.57862e-28 (rank : 11)
Query Neighborhood Hits	117	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	Q99388	Gene names	D1Lub1, Sp100-rs
Domain Architecture
Description	Putative Sp100-related protein.

SSRP1_HUMAN
NC score	0.545753 (rank : 11)	θ value	7.84624e-12 (rank : 14)
Query Neighborhood Hits	117	Target Neighborhood Hits	187	Shared Neighborhood Hits	72
SwissProt Accessions	Q08945, Q5BJG8	Gene names	SSRP1, FACT80
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (FACT 80 kDa subunit) (FACTp80) (Chromatin- specific transcription elongation factor 80 kDa subunit) (Structure- specific recognition protein 1) (hSSRP1) (Recombination signal sequence recognition protein 1) (T160).

SSRP1_MOUSE
NC score	0.535322 (rank : 12)	θ value	1.133e-10 (rank : 17)
Query Neighborhood Hits	117	Target Neighborhood Hits	193	Shared Neighborhood Hits	71
SwissProt Accessions	Q08943, Q3U9Z2, Q3UJ75, Q4V9U4, Q8CGA6	Gene names	Ssrp1
Domain Architecture
Description	FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Structure-specific recognition protein 1) (Recombination signal sequence recognition protein 1) (T160).

IPR1_MOUSE
NC score	0.519737 (rank : 13)	θ value	7.56453e-23 (rank : 13)
Query Neighborhood Hits	117	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

HM20B_MOUSE
NC score	0.510639 (rank : 14)	θ value	4.76016e-09 (rank : 18)
Query Neighborhood Hits	117	Target Neighborhood Hits	122	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z104, Q9NSF7, Q9NSF8	Gene names	Hmg20b, Braf35, Hmgx2, Smarce1r
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35).

HM2L1_HUMAN
NC score	0.498060 (rank : 15)	θ value	2.21117e-06 (rank : 23)
Query Neighborhood Hits	117	Target Neighborhood Hits	130	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UGU5, O75672, O75673, Q9UMT5	Gene names	HMG2L1, HMGBCG
Domain Architecture
Description	High mobility group protein 2-like 1 (Protein HMGBCG).

TFAM_MOUSE
NC score	0.496718 (rank : 16)	θ value	5.81887e-07 (rank : 22)
Query Neighborhood Hits	117	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

LY10_HUMAN
NC score	0.494843 (rank : 17)	θ value	1.14825e-79 (rank : 2)
Query Neighborhood Hits	117	Target Neighborhood Hits	151	Shared Neighborhood Hits	19
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

HM20B_HUMAN
NC score	0.493442 (rank : 18)	θ value	1.99992e-07 (rank : 19)
Query Neighborhood Hits	117	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q9P0W2, Q6IBP8, Q8NBD5, Q9HD21, Q9Y491, Q9Y4A2	Gene names	HMG20B, BRAF35, HMGX2, SMARCE1R
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (HMG domain protein HMG20B) (Structural DNA-binding protein BRAF35) (BRCA2- associated factor 35) (Sox-like transcriptional factor).

TFAM_HUMAN
NC score	0.468291 (rank : 19)	θ value	1.43324e-05 (rank : 28)
Query Neighborhood Hits	117	Target Neighborhood Hits	156	Shared Neighborhood Hits	63
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

SP110_HUMAN
NC score	0.456081 (rank : 20)	θ value	2.12685e-25 (rank : 12)
Query Neighborhood Hits	117	Target Neighborhood Hits	141	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

HM20A_HUMAN
NC score	0.450675 (rank : 21)	θ value	2.61198e-07 (rank : 20)
Query Neighborhood Hits	117	Target Neighborhood Hits	343	Shared Neighborhood Hits	70
SwissProt Accessions	Q9NP66, Q53G31, Q9NSF6	Gene names	HMG20A, HMGX1
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1).

HM20A_MOUSE
NC score	0.448928 (rank : 22)	θ value	2.61198e-07 (rank : 21)
Query Neighborhood Hits	117	Target Neighborhood Hits	348	Shared Neighborhood Hits	70
SwissProt Accessions	Q9DC33, Q3LSF9, Q6NV87, Q8BSK1, Q8C3C1, Q8CAA0, Q9CYG2	Gene names	Hmg20a, Ibraf
Domain Architecture	No domain graphic available
Description	High mobility group protein 20A (HMG box-containing protein 20A) (iBRAF) (Inhibitor of BRAF35) (HMG domain protein HMGX1).

CN092_HUMAN
NC score	0.425006 (rank : 23)	θ value	1.09739e-05 (rank : 26)
Query Neighborhood Hits	117	Target Neighborhood Hits	143	Shared Neighborhood Hits	56
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CN092_MOUSE
NC score	0.416972 (rank : 24)	θ value	1.09739e-05 (rank : 27)
Query Neighborhood Hits	117	Target Neighborhood Hits	206	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

TOX_MOUSE
NC score	0.415993 (rank : 25)	θ value	0.000786445 (rank : 33)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	Q66JW3, Q8BKH9, Q8BYQ5, Q8R4H0	Gene names	Tox
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

TOX_HUMAN
NC score	0.411744 (rank : 26)	θ value	0.00102713 (rank : 36)
Query Neighborhood Hits	117	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	O94900, Q96AV5	Gene names	TOX, KIAA0808
Domain Architecture	No domain graphic available
Description	Thymus high mobility group box protein TOX.

UBF1_HUMAN
NC score	0.387550 (rank : 27)	θ value	8.40245e-06 (rank : 25)
Query Neighborhood Hits	117	Target Neighborhood Hits	415	Shared Neighborhood Hits	72
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

UBF1_MOUSE
NC score	0.380479 (rank : 28)	θ value	6.43352e-06 (rank : 24)
Query Neighborhood Hits	117	Target Neighborhood Hits	419	Shared Neighborhood Hits	72
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

GCX1_HUMAN
NC score	0.367070 (rank : 29)	θ value	0.00509761 (rank : 38)
Query Neighborhood Hits	117	Target Neighborhood Hits	132	Shared Neighborhood Hits	47
SwissProt Accessions	Q96NM4, Q5TE33, Q5TE34, Q5TE35, Q96IC9, Q9BQN5	Gene names	GCX1, C20orf100
Domain Architecture
Description	Granulosa cell HMG box protein 1 (GCX-1).

BBX_MOUSE
NC score	0.345761 (rank : 30)	θ value	9.29e-05 (rank : 29)
Query Neighborhood Hits	117	Target Neighborhood Hits	152	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

BBX_HUMAN
NC score	0.343717 (rank : 31)	θ value	0.000121331 (rank : 30)
Query Neighborhood Hits	117	Target Neighborhood Hits	167	Shared Neighborhood Hits	65
SwissProt Accessions	Q8WY36, Q2TAJ1, Q7L3J8, Q7LBY8, Q8NDB0, Q8WY35, Q9H0J6	Gene names	BBX, HBP2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

DEAF1_HUMAN
NC score	0.311579 (rank : 32)	θ value	6.64225e-11 (rank : 15)
Query Neighborhood Hits	117	Target Neighborhood Hits	67	Shared Neighborhood Hits	15
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

DEAF1_MOUSE
NC score	0.310011 (rank : 33)	θ value	6.64225e-11 (rank : 16)
Query Neighborhood Hits	117	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z1T5	Gene names	Deaf1
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR).

SOX8_HUMAN
NC score	0.306579 (rank : 34)	θ value	0.00390308 (rank : 37)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	63
SwissProt Accessions	P57073, Q9NZW2	Gene names	SOX8
Domain Architecture
Description	Transcription factor SOX-8.

SOX8_MOUSE
NC score	0.306513 (rank : 35)	θ value	0.00509761 (rank : 39)
Query Neighborhood Hits	117	Target Neighborhood Hits	96	Shared Neighborhood Hits	63
SwissProt Accessions	Q04886	Gene names	Sox8, Sox-8
Domain Architecture
Description	Transcription factor SOX-8.

SOX2_MOUSE
NC score	0.297663 (rank : 36)	θ value	0.00869519 (rank : 43)
Query Neighborhood Hits	117	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	P48432	Gene names	Sox2, Sox-2
Domain Architecture
Description	Transcription factor SOX-2.

SOX2_HUMAN
NC score	0.297547 (rank : 37)	θ value	0.00869519 (rank : 42)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	P48431, Q14537	Gene names	SOX2
Domain Architecture
Description	Transcription factor SOX-2.

SOX18_HUMAN
NC score	0.295906 (rank : 38)	θ value	0.0148317 (rank : 46)
Query Neighborhood Hits	117	Target Neighborhood Hits	106	Shared Neighborhood Hits	64
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

SOX15_HUMAN
NC score	0.294347 (rank : 39)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	117	Target Neighborhood Hits	134	Shared Neighborhood Hits	68
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

SOX14_HUMAN
NC score	0.294105 (rank : 40)	θ value	0.0563607 (rank : 51)
Query Neighborhood Hits	117	Target Neighborhood Hits	102	Shared Neighborhood Hits	68
SwissProt Accessions	O95416, Q3KPH7	Gene names	SOX14, SOX28
Domain Architecture
Description	Transcription factor SOX-14.

SOX14_MOUSE
NC score	0.294100 (rank : 41)	θ value	0.0563607 (rank : 52)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	68
SwissProt Accessions	Q04892, Q9JLC9, Q9JLD0, Q9QXU4	Gene names	Sox14, Sox-14
Domain Architecture
Description	Transcription factor SOX-14.

SOX9_MOUSE
NC score	0.293685 (rank : 42)	θ value	0.0113563 (rank : 45)
Query Neighborhood Hits	117	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	Q04887, Q8C7L2, Q91ZK2, Q99KQ0	Gene names	Sox9, Sox-9
Domain Architecture
Description	Transcription factor SOX-9.

SOX9_HUMAN
NC score	0.292783 (rank : 43)	θ value	0.0113563 (rank : 44)
Query Neighborhood Hits	117	Target Neighborhood Hits	210	Shared Neighborhood Hits	64
SwissProt Accessions	P48436	Gene names	SOX9
Domain Architecture
Description	Transcription factor SOX-9.

SOX15_MOUSE
NC score	0.288389 (rank : 44)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	68
SwissProt Accessions	P43267, O70204, P70418, Q62246, Q91V00, Q91V43, Q920T1, Q9JLG2	Gene names	Sox15, Sox-15
Domain Architecture
Description	SOX-15 protein.

SOX12_HUMAN
NC score	0.286831 (rank : 45)	θ value	0.365318 (rank : 63)
Query Neighborhood Hits	117	Target Neighborhood Hits	111	Shared Neighborhood Hits	63
SwissProt Accessions	O15370, Q9NUD4	Gene names	SOX12, SOX22
Domain Architecture
Description	SOX-12 protein (SOX-22 protein).

SOX10_MOUSE
NC score	0.286747 (rank : 46)	θ value	0.00869519 (rank : 41)
Query Neighborhood Hits	117	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q04888, O08518, O09141, O54856, P70416	Gene names	Sox10, Sox-10, Sox21
Domain Architecture
Description	Transcription factor SOX-10 (SOX-21) (Transcription factor SOX-M).

SOX10_HUMAN
NC score	0.286389 (rank : 47)	θ value	0.00869519 (rank : 40)
Query Neighborhood Hits	117	Target Neighborhood Hits	122	Shared Neighborhood Hits	59
SwissProt Accessions	P56693	Gene names	SOX10
Domain Architecture
Description	Transcription factor SOX-10.

SOX12_MOUSE
NC score	0.285982 (rank : 48)	θ value	0.365318 (rank : 64)
Query Neighborhood Hits	117	Target Neighborhood Hits	98	Shared Neighborhood Hits	63
SwissProt Accessions	Q04890, P70417, Q6NXL2	Gene names	Sox12, Sox-12
Domain Architecture	No domain graphic available
Description	SOX-12 protein.

SRY_HUMAN
NC score	0.285402 (rank : 49)	θ value	0.125558 (rank : 54)
Query Neighborhood Hits	117	Target Neighborhood Hits	83	Shared Neighborhood Hits	68
SwissProt Accessions	Q05066	Gene names	SRY, TDF
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX21_HUMAN
NC score	0.282222 (rank : 50)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y651, P35715, Q15504	Gene names	SOX21, SOX25, SOXA
Domain Architecture
Description	Transcription factor SOX-21 (SOX-A).

SOX21_MOUSE
NC score	0.282215 (rank : 51)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	117	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	Q811W0, Q8VH35	Gene names	Sox21
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-21.

SOX4_MOUSE
NC score	0.279003 (rank : 52)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	117	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	Q06831	Gene names	Sox4, Sox-4
Domain Architecture
Description	Transcription factor SOX-4.

SOX18_MOUSE
NC score	0.278433 (rank : 53)	θ value	0.365318 (rank : 65)
Query Neighborhood Hits	117	Target Neighborhood Hits	105	Shared Neighborhood Hits	63
SwissProt Accessions	P43680, Q9EQ73	Gene names	Sox18, Sox-18
Domain Architecture
Description	Transcription factor SOX-18.

PMS1_HUMAN
NC score	0.278390 (rank : 54)	θ value	0.125558 (rank : 53)
Query Neighborhood Hits	117	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	P54277	Gene names	PMS1, PMSL1
Domain Architecture
Description	PMS1 protein homolog 1 (DNA mismatch repair protein PMS1).

SOX1_HUMAN
NC score	0.276355 (rank : 55)	θ value	0.365318 (rank : 66)
Query Neighborhood Hits	117	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	O00570	Gene names	SOX1
Domain Architecture
Description	SOX-1 protein.

SOX4_HUMAN
NC score	0.276199 (rank : 56)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	117	Target Neighborhood Hits	111	Shared Neighborhood Hits	67
SwissProt Accessions	Q06945	Gene names	SOX4
Domain Architecture
Description	Transcription factor SOX-4.

SOX1_MOUSE
NC score	0.275889 (rank : 57)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	117	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	P53783	Gene names	Sox1, Sox-1
Domain Architecture
Description	SOX-1 protein.

SOX30_MOUSE
NC score	0.274092 (rank : 58)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	117	Target Neighborhood Hits	374	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SRY_MOUSE
NC score	0.273990 (rank : 59)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	117	Target Neighborhood Hits	139	Shared Neighborhood Hits	69
SwissProt Accessions	Q05738	Gene names	Sry, Tdf, Tdy
Domain Architecture
Description	Sex-determining region Y protein (Testis-determining factor).

SOX30_HUMAN
NC score	0.272326 (rank : 60)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	117	Target Neighborhood Hits	305	Shared Neighborhood Hits	67
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SOX3_MOUSE
NC score	0.271894 (rank : 61)	θ value	0.62314 (rank : 75)
Query Neighborhood Hits	117	Target Neighborhood Hits	101	Shared Neighborhood Hits	67
SwissProt Accessions	P53784	Gene names	Sox3, Sox-3
Domain Architecture
Description	Transcription factor SOX-3.

HBP1_HUMAN
NC score	0.271450 (rank : 62)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	61
SwissProt Accessions	O60381, Q8TBM1, Q8TE93, Q96AJ2	Gene names	HBP1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

SOX7_MOUSE
NC score	0.270416 (rank : 63)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	117	Target Neighborhood Hits	105	Shared Neighborhood Hits	67
SwissProt Accessions	P40646, Q9R1T6	Gene names	Sox7, Sox-7
Domain Architecture
Description	Transcription factor SOX-7 (mSOX7).

SOX3_HUMAN
NC score	0.270219 (rank : 64)	θ value	0.62314 (rank : 74)
Query Neighborhood Hits	117	Target Neighborhood Hits	109	Shared Neighborhood Hits	67
SwissProt Accessions	P41225, P35714, Q9NP49	Gene names	SOX3
Domain Architecture
Description	Transcription factor SOX-3.

HBP1_MOUSE
NC score	0.270170 (rank : 65)	θ value	0.0563607 (rank : 50)
Query Neighborhood Hits	117	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	Q8R316, Q3V0I4, Q8BUS3, Q8C199	Gene names	Hbp1
Domain Architecture	No domain graphic available
Description	HMG box-containing protein 1 (HMG box transcription factor 1) (High mobility group box transcription factor 1).

SMCE1_HUMAN
NC score	0.269192 (rank : 66)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	117	Target Neighborhood Hits	272	Shared Neighborhood Hits	64
SwissProt Accessions	Q969G3, O43539	Gene names	SMARCE1, BAF57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57).

SOX11_HUMAN
NC score	0.268280 (rank : 67)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	117	Target Neighborhood Hits	89	Shared Neighborhood Hits	66
SwissProt Accessions	P35716	Gene names	SOX11
Domain Architecture
Description	Transcription factor SOX-11.

SOX11_MOUSE
NC score	0.266592 (rank : 68)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	117	Target Neighborhood Hits	96	Shared Neighborhood Hits	66
SwissProt Accessions	Q7M6Y2, O35178, O89036, Q04889, Q80XF0	Gene names	Sox11, Sox-11
Domain Architecture	No domain graphic available
Description	Transcription factor SOX-11.

SOX7_HUMAN
NC score	0.266493 (rank : 69)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	117	Target Neighborhood Hits	140	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BT81	Gene names	SOX7
Domain Architecture
Description	Transcription factor SOX-7.

SOX17_MOUSE
NC score	0.258219 (rank : 70)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	117	Target Neighborhood Hits	223	Shared Neighborhood Hits	65
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

CIC_MOUSE
NC score	0.256035 (rank : 71)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	117	Target Neighborhood Hits	742	Shared Neighborhood Hits	66
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SOX17_HUMAN
NC score	0.255265 (rank : 72)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	117	Target Neighborhood Hits	108	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H6I2	Gene names	SOX17
Domain Architecture
Description	Transcription factor SOX-17.

SMCE1_MOUSE
NC score	0.254040 (rank : 73)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	117	Target Neighborhood Hits	409	Shared Neighborhood Hits	65
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

CIC_HUMAN
NC score	0.242309 (rank : 74)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	117	Target Neighborhood Hits	992	Shared Neighborhood Hits	70
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SOX6_HUMAN
NC score	0.241398 (rank : 75)	θ value	0.62314 (rank : 76)
Query Neighborhood Hits	117	Target Neighborhood Hits	332	Shared Neighborhood Hits	71
SwissProt Accessions	P35712, Q9BXQ3, Q9BXQ4, Q9BXQ5, Q9H0I8	Gene names	SOX6
Domain Architecture
Description	Transcription factor SOX-6.

SOX6_MOUSE
NC score	0.241322 (rank : 76)	θ value	0.62314 (rank : 77)
Query Neighborhood Hits	117	Target Neighborhood Hits	341	Shared Neighborhood Hits	71
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

PB1_HUMAN
NC score	0.241198 (rank : 77)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	117	Target Neighborhood Hits	261	Shared Neighborhood Hits	69
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

SOX13_MOUSE
NC score	0.239684 (rank : 78)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	117	Target Neighborhood Hits	495	Shared Neighborhood Hits	70
SwissProt Accessions	Q04891, Q922L3	Gene names	Sox13, Sox-13
Domain Architecture
Description	SOX-13 protein.

SOX13_HUMAN
NC score	0.239009 (rank : 79)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	117	Target Neighborhood Hits	464	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SOX5_MOUSE
NC score	0.227023 (rank : 80)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	117	Target Neighborhood Hits	196	Shared Neighborhood Hits	67
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

SOX5_HUMAN
NC score	0.226175 (rank : 81)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	117	Target Neighborhood Hits	219	Shared Neighborhood Hits	67
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

GMEB1_MOUSE
NC score	0.205503 (rank : 82)	θ value	0.00020696 (rank : 31)
Query Neighborhood Hits	117	Target Neighborhood Hits	60	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JL60	Gene names	Gmeb1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1).

GMEB1_HUMAN
NC score	0.204962 (rank : 83)	θ value	0.000270298 (rank : 32)
Query Neighborhood Hits	117	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y692, Q9NWH1, Q9UKD0	Gene names	GMEB1
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 1 (GMEB-1) (Parvovirus initiation factor p96) (PIF p96) (DNA-binding protein p96PIF).

GMEB2_MOUSE
NC score	0.201246 (rank : 84)	θ value	0.00102713 (rank : 35)
Query Neighborhood Hits	117	Target Neighborhood Hits	64	Shared Neighborhood Hits	10
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

GMEB2_HUMAN
NC score	0.201013 (rank : 85)	θ value	0.00102713 (rank : 34)
Query Neighborhood Hits	117	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

TCF7_HUMAN
NC score	0.131389 (rank : 86)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	117	Target Neighborhood Hits	186	Shared Neighborhood Hits	57
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TCF7_MOUSE
NC score	0.127192 (rank : 87)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	117	Target Neighborhood Hits	277	Shared Neighborhood Hits	55
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

LEF1_HUMAN
NC score	0.122396 (rank : 88)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	117	Target Neighborhood Hits	150	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UJU2, Q9HAZ0	Gene names	LEF1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1) (T cell-specific transcription factor 1-alpha) (TCF1-alpha).

LEF1_MOUSE
NC score	0.122241 (rank : 89)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	117	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	P27782	Gene names	Lef1, Lef-1
Domain Architecture
Description	Lymphoid enhancer-binding factor 1 (LEF-1).

AIRE_MOUSE
NC score	0.117907 (rank : 90)	θ value	0.0563607 (rank : 48)
Query Neighborhood Hits	117	Target Neighborhood Hits	196	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AIRE_HUMAN
NC score	0.115129 (rank : 91)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	117	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

TF7L1_HUMAN
NC score	0.104760 (rank : 92)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	117	Target Neighborhood Hits	129	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCS4, Q53R97, Q6PD70, Q9NP00	Gene names	TCF7L1, TCF3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF- 3).

TF7L2_HUMAN
NC score	0.104754 (rank : 93)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	117	Target Neighborhood Hits	119	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NQB0, O00185, Q9NQB1, Q9NQB2, Q9NQB3, Q9NQB4, Q9NQB5, Q9NQB6, Q9NQB7, Q9ULC2	Gene names	TCF7L2, TCF4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (hTCF-4).

TF7L2_MOUSE
NC score	0.104402 (rank : 94)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	117	Target Neighborhood Hits	95	Shared Neighborhood Hits	52
SwissProt Accessions	Q924A0, O70574, Q91XP2, Q91XP3, Q91XP4, Q924A1, Q9Z0V3, Q9Z0V4	Gene names	Tcf7l2, Tcf4
Domain Architecture
Description	Transcription factor 7-like 2 (HMG box transcription factor 4) (T- cell-specific transcription factor 4) (TCF-4) (mTCF-4).

TF7L1_MOUSE
NC score	0.104213 (rank : 95)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	117	Target Neighborhood Hits	131	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z1J1, O70450, O70573	Gene names	Tcf7l1, Tcf3
Domain Architecture
Description	Transcription factor 7-like 1 (HMG box transcription factor 3) (TCF-3) (mTCF-3).

TRI66_HUMAN
NC score	0.054370 (rank : 96)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	117	Target Neighborhood Hits	479	Shared Neighborhood Hits	15
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
NC score	0.052857 (rank : 97)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	117	Target Neighborhood Hits	491	Shared Neighborhood Hits	19
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1A_MOUSE
NC score	0.050210 (rank : 98)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	117	Target Neighborhood Hits	307	Shared Neighborhood Hits	8
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

PKCB1_HUMAN
NC score	0.050032 (rank : 99)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	117	Target Neighborhood Hits	488	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

WDHD1_HUMAN
NC score	0.038924 (rank : 100)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	117	Target Neighborhood Hits	342	Shared Neighborhood Hits	17
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

ATRX_MOUSE
NC score	0.037496 (rank : 101)	θ value	0.279714 (rank : 61)
Query Neighborhood Hits	117	Target Neighborhood Hits	682	Shared Neighborhood Hits	21
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CG024_MOUSE
NC score	0.027461 (rank : 102)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	117	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7X8, Q3URJ2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C7orf24 homolog.

DIP2A_HUMAN
NC score	0.025441 (rank : 103)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	117	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

BAZ1A_HUMAN
NC score	0.024263 (rank : 104)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	117	Target Neighborhood Hits	693	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

NIPBL_HUMAN
NC score	0.023130 (rank : 105)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	117	Target Neighborhood Hits	1311	Shared Neighborhood Hits	29
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

CG024_HUMAN
NC score	0.020614 (rank : 106)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	117	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	O75223	Gene names	C7orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C7orf24.

MLL3_MOUSE
NC score	0.020579 (rank : 107)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	117	Target Neighborhood Hits	1399	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MEPD_HUMAN
NC score	0.019090 (rank : 108)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	117	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P52888, Q9UCB3	Gene names	THOP1
Domain Architecture
Description	Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78).

CJ068_HUMAN
NC score	0.018451 (rank : 109)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	117	Target Neighborhood Hits	316	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

PLCB3_MOUSE
NC score	0.015830 (rank : 110)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	117	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	P51432	Gene names	Plcb3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

SH3G2_MOUSE
NC score	0.015551 (rank : 111)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	117	Target Neighborhood Hits	319	Shared Neighborhood Hits	8
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

SH3G2_HUMAN
NC score	0.014854 (rank : 112)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	117	Target Neighborhood Hits	324	Shared Neighborhood Hits	8
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

FGD6_HUMAN
NC score	0.014788 (rank : 113)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	117	Target Neighborhood Hits	237	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

P66A_HUMAN
NC score	0.014493 (rank : 114)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	117	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q86YP4, Q7L3J2, Q96F28, Q9NPU2, Q9NXS1	Gene names	GATAD2A
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 alpha (Hp66alpha) (GATA zinc finger domain-containing protein 2A).

ETV7_HUMAN
NC score	0.014142 (rank : 115)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	117	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y603, Q9NZ65, Q9NZ66, Q9NZ68, Q9NZR8, Q9UNJ7, Q9Y5K4, Q9Y604	Gene names	ETV7, TEL2, TELB, TREF
Domain Architecture
Description	Transcription factor ETV7 (Transcription factor Tel-2) (ETS-related protein Tel2) (Tel-related Ets factor).

RN169_HUMAN
NC score	0.013306 (rank : 116)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	117	Target Neighborhood Hits	203	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

SYCP2_HUMAN
NC score	0.013094 (rank : 117)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	117	Target Neighborhood Hits	230	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

SRGP2_MOUSE
NC score	0.010558 (rank : 118)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	117	Target Neighborhood Hits	324	Shared Neighborhood Hits	9
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

REPS1_HUMAN
NC score	0.009783 (rank : 119)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	117	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q96D71, Q8NDR7, Q8WU62, Q9BXY9	Gene names	REPS1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

SRGP2_HUMAN
NC score	0.009396 (rank : 120)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	117	Target Neighborhood Hits	331	Shared Neighborhood Hits	9
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

CLC1A_MOUSE
NC score	0.008243 (rank : 121)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	117	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWY2, Q7TPX7, Q8BMH5	Gene names	Clec1a
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 1 member A.

IL1R1_HUMAN
NC score	0.006885 (rank : 122)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	117	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

BLM_HUMAN
NC score	0.006812 (rank : 123)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	117	Target Neighborhood Hits	148	Shared Neighborhood Hits	2
SwissProt Accessions	P54132	Gene names	BLM, RECQ2, RECQL3
Domain Architecture
Description	Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase, RecQ-like type 2).

MYH10_HUMAN
NC score	0.006707 (rank : 124)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	117	Target Neighborhood Hits	1620	Shared Neighborhood Hits	22
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.006300 (rank : 125)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	117	Target Neighborhood Hits	1612	Shared Neighborhood Hits	22
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

KIF4A_HUMAN
NC score	0.004597 (rank : 126)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	117	Target Neighborhood Hits	1159	Shared Neighborhood Hits	16
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

PDE3A_HUMAN
NC score	0.004543 (rank : 127)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	117	Target Neighborhood Hits	79	Shared Neighborhood Hits	2
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

SPAG1_MOUSE
NC score	0.004286 (rank : 128)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	117	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

RBP24_HUMAN
NC score	0.002548 (rank : 129)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	117	Target Neighborhood Hits	1559	Shared Neighborhood Hits	19
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.002503 (rank : 130)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	117	Target Neighborhood Hits	1558	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

STK10_HUMAN
NC score	0.000572 (rank : 131)	θ value	0.62314 (rank : 78)
Query Neighborhood Hits	117	Target Neighborhood Hits	1921	Shared Neighborhood Hits	21
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

NKX61_MOUSE
NC score	0.000216 (rank : 132)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	117	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

1B47_HUMAN
NC score	-0.001215 (rank : 133)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	117	Target Neighborhood Hits	211	Shared Neighborhood Hits	2
SwissProt Accessions	P30485, O19555, O77933, Q95392, Q9GIL3	Gene names	HLA-B, HLAB
Domain Architecture
Description	HLA class I histocompatibility antigen, B-47 alpha chain precursor (MHC class I antigen B*47) (Bw-47).

VGFR1_MOUSE
NC score	-0.003196 (rank : 134)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	117	Target Neighborhood Hits	1118	Shared Neighborhood Hits	4
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

ZN174_HUMAN
NC score	-0.004528 (rank : 135)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	117	Target Neighborhood Hits	744	Shared Neighborhood Hits	2
SwissProt Accessions	Q15697, Q9BQ34	Gene names	ZNF174, ZSCAN8
Domain Architecture
Description	Zinc finger protein 174 (AW-1) (Zinc finger and SCAN domain-containing protein 8).