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Network neighborhood for query Sequence : PDE3A_HUMAN

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PDE3A_HUMAN
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PDE3A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	79	Target Neighborhood Hits	79	Shared Neighborhood Hits	79
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDE3A_MOUSE
θ value	0 (rank : 2)	NC score	0.993518 (rank : 2)
Query Neighborhood Hits	79	Target Neighborhood Hits	115	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDE3B_HUMAN
θ value	0 (rank : 3)	NC score	0.986246 (rank : 3)
Query Neighborhood Hits	79	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q13370, O00639, Q14408	Gene names	PDE3B
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).

PDE1C_MOUSE
θ value	1.51363e-47 (rank : 4)	NC score	0.903157 (rank : 9)
Query Neighborhood Hits	79	Target Neighborhood Hits	161	Shared Neighborhood Hits	40
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

PDE1A_HUMAN
θ value	1.97686e-47 (rank : 5)	NC score	0.912191 (rank : 5)
Query Neighborhood Hits	79	Target Neighborhood Hits	42	Shared Neighborhood Hits	38
SwissProt Accessions	P54750, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2, Q9C0L3, Q9C0L4, Q9UFX3	Gene names	PDE1A
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE) (hCam-1).

PDE1A_MOUSE
θ value	1.97686e-47 (rank : 6)	NC score	0.912732 (rank : 4)
Query Neighborhood Hits	79	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q61481, O35388	Gene names	Pde1a
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE).

PDE1C_HUMAN
θ value	2.85459e-46 (rank : 7)	NC score	0.903226 (rank : 8)
Query Neighborhood Hits	79	Target Neighborhood Hits	134	Shared Neighborhood Hits	42
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).

PDE4D_MOUSE
θ value	1.73182e-43 (rank : 8)	NC score	0.892901 (rank : 13)
Query Neighborhood Hits	79	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	Q01063, Q6TRH9, Q8C4Q7, Q8CG05	Gene names	Pde4d
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3).

PDE4D_HUMAN
θ value	3.85808e-43 (rank : 9)	NC score	0.891950 (rank : 15)
Query Neighborhood Hits	79	Target Neighborhood Hits	122	Shared Neighborhood Hits	38
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

PDE4A_MOUSE
θ value	6.58091e-43 (rank : 10)	NC score	0.893722 (rank : 12)
Query Neighborhood Hits	79	Target Neighborhood Hits	66	Shared Neighborhood Hits	39
SwissProt Accessions	O89084, Q8R078, Q9JHQ4, Q9QX48, Q9QX49, Q9QXI8	Gene names	Pde4a
Domain Architecture
Description	cAMP-dependent 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17).

PDE4A_HUMAN
θ value	1.91475e-42 (rank : 11)	NC score	0.892752 (rank : 14)
Query Neighborhood Hits	79	Target Neighborhood Hits	73	Shared Neighborhood Hits	38
SwissProt Accessions	P27815, O75522, O76092, Q16255, Q16691, Q8WUQ3	Gene names	PDE4A
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).

PDE4B_HUMAN
θ value	1.91475e-42 (rank : 12)	NC score	0.894942 (rank : 10)
Query Neighborhood Hits	79	Target Neighborhood Hits	65	Shared Neighborhood Hits	38
SwissProt Accessions	Q07343, O15443	Gene names	PDE4B
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.17) (DPDE4) (PDE32).

PDE1B_MOUSE
θ value	8.04462e-41 (rank : 13)	NC score	0.908470 (rank : 6)
Query Neighborhood Hits	79	Target Neighborhood Hits	46	Shared Neighborhood Hits	38
SwissProt Accessions	Q01065, O35384	Gene names	Pde1b, Pde1b1
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (EC 3.1.4.17) (Cam-PDE 1B) (63 kDa Cam-PDE).

PDE1B_HUMAN
θ value	1.79215e-40 (rank : 14)	NC score	0.907457 (rank : 7)
Query Neighborhood Hits	79	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	Q01064, Q92825	Gene names	PDE1B, PDE1B1
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (EC 3.1.4.17) (Cam-PDE 1B) (63 kDa Cam-PDE).

PDE4C_MOUSE
θ value	7.52953e-39 (rank : 15)	NC score	0.894584 (rank : 11)
Query Neighborhood Hits	79	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q3UEI1, Q8K0P4	Gene names	Pde4c
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17).

PDE4C_HUMAN
θ value	1.6774e-38 (rank : 16)	NC score	0.891430 (rank : 16)
Query Neighborhood Hits	79	Target Neighborhood Hits	56	Shared Neighborhood Hits	39
SwissProt Accessions	Q08493, Q9UN44, Q9UN45, Q9UN46, Q9UPJ6	Gene names	PDE4C
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17) (DPDE1) (PDE21).

PDE8B_HUMAN
θ value	3.4976e-36 (rank : 17)	NC score	0.888103 (rank : 17)
Query Neighborhood Hits	79	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95263, Q86XK8, Q8IUJ7, Q8IUJ8, Q8IUJ9, Q8IUK0, Q8N3T2	Gene names	PDE8B
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (EC 3.1.4.17) (HSPDE8B).

PDE8A_MOUSE
θ value	6.59618e-35 (rank : 18)	NC score	0.885095 (rank : 20)
Query Neighborhood Hits	79	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	O88502	Gene names	Pde8a, Pde8
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17) (MMPDE8).

PDE8A_HUMAN
θ value	3.27365e-34 (rank : 19)	NC score	0.885040 (rank : 21)
Query Neighborhood Hits	79	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O60658, Q969I1, Q96PC9, Q96PD0, Q96PD1, Q9UMB7	Gene names	PDE8A
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17).

PDE7A_HUMAN
θ value	2.19584e-30 (rank : 20)	NC score	0.886066 (rank : 19)
Query Neighborhood Hits	79	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	Q13946, O15380	Gene names	PDE7A
Domain Architecture
Description	High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (EC 3.1.4.17) (HCP1) (TM22).

PDE7A_MOUSE
θ value	3.74554e-30 (rank : 21)	NC score	0.886794 (rank : 18)
Query Neighborhood Hits	79	Target Neighborhood Hits	39	Shared Neighborhood Hits	38
SwissProt Accessions	P70453, Q9ERB3	Gene names	Pde7a
Domain Architecture
Description	High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (EC 3.1.4.17) (P2A).

PDE9A_HUMAN
θ value	1.57365e-28 (rank : 22)	NC score	0.874453 (rank : 25)
Query Neighborhood Hits	79	Target Neighborhood Hits	93	Shared Neighborhood Hits	39
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDE9A_MOUSE
θ value	2.05525e-28 (rank : 23)	NC score	0.878117 (rank : 24)
Query Neighborhood Hits	79	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	O70628	Gene names	Pde9a, Pde8b
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDE7B_MOUSE
θ value	8.63488e-27 (rank : 24)	NC score	0.881010 (rank : 22)
Query Neighborhood Hits	79	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXQ1	Gene names	Pde7b
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 7B (EC 3.1.4.17).

PDE7B_HUMAN
θ value	1.62847e-25 (rank : 25)	NC score	0.878797 (rank : 23)
Query Neighborhood Hits	79	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP56	Gene names	PDE7B
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 7B (EC 3.1.4.17).

PDE2A_HUMAN
θ value	1.02238e-19 (rank : 26)	NC score	0.791781 (rank : 27)
Query Neighborhood Hits	79	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O00408	Gene names	PDE2A
Domain Architecture
Description	cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE).

PDE2A_MOUSE
θ value	1.02238e-19 (rank : 27)	NC score	0.792778 (rank : 26)
Query Neighborhood Hits	79	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	Q922S4, Q8K2U1	Gene names	Pde2a
Domain Architecture	No domain graphic available
Description	cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE).

PDE11_HUMAN
θ value	8.65492e-19 (rank : 28)	NC score	0.765620 (rank : 28)
Query Neighborhood Hits	79	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCR9, Q53T16, Q96S76, Q9GZY7, Q9HB46, Q9NY45	Gene names	PDE11A
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

PDE11_MOUSE
θ value	1.92812e-18 (rank : 29)	NC score	0.764956 (rank : 29)
Query Neighborhood Hits	79	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	P0C1Q2	Gene names	Pde11a
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

PDE6C_HUMAN
θ value	4.02038e-16 (rank : 30)	NC score	0.730039 (rank : 34)
Query Neighborhood Hits	79	Target Neighborhood Hits	56	Shared Neighborhood Hits	39
SwissProt Accessions	P51160, Q5VY29	Gene names	PDE6C, PDEA2
Domain Architecture
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PDE6C_MOUSE
θ value	8.95645e-16 (rank : 31)	NC score	0.730291 (rank : 33)
Query Neighborhood Hits	79	Target Neighborhood Hits	45	Shared Neighborhood Hits	38
SwissProt Accessions	Q91ZQ1, Q8R0D4	Gene names	Pde6c
Domain Architecture	No domain graphic available
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PDE6A_HUMAN
θ value	2.20605e-14 (rank : 32)	NC score	0.723404 (rank : 35)
Query Neighborhood Hits	79	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	P16499	Gene names	PDE6A, PDEA
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha) (PDE V-B1).

PDE6A_MOUSE
θ value	4.91457e-14 (rank : 33)	NC score	0.719786 (rank : 36)
Query Neighborhood Hits	79	Target Neighborhood Hits	45	Shared Neighborhood Hits	38
SwissProt Accessions	P27664	Gene names	Pde6a, Mpa, Pdea
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha).

PDE6B_HUMAN
θ value	1.86753e-13 (rank : 34)	NC score	0.719321 (rank : 37)
Query Neighborhood Hits	79	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	P35913, Q9BWH5	Gene names	PDE6B, PDEB
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase beta-subunit precursor (EC 3.1.4.35) (GMP-PDE beta).

PDE6B_MOUSE
θ value	3.52202e-12 (rank : 35)	NC score	0.714793 (rank : 38)
Query Neighborhood Hits	79	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	P23440	Gene names	Pde6b, Mpb, Pdeb, rd
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta precursor (EC 3.1.4.35) (GMP-PDE beta).

PDE10_HUMAN
θ value	2.98157e-11 (rank : 36)	NC score	0.750970 (rank : 30)
Query Neighborhood Hits	79	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y233, Q9Y5T1	Gene names	PDE10A
Domain Architecture
Description	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17).

PDE5A_HUMAN
θ value	2.98157e-11 (rank : 37)	NC score	0.731002 (rank : 32)
Query Neighborhood Hits	79	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	O76074, O75026, O75887, Q86UI0, Q86V66, Q9Y6Z6	Gene names	PDE5A, PDE5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

PDE5A_MOUSE
θ value	2.52405e-10 (rank : 38)	NC score	0.732189 (rank : 31)
Query Neighborhood Hits	79	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG03	Gene names	Pde5a, Pde5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

KI18A_HUMAN
θ value	0.163984 (rank : 39)	NC score	0.009098 (rank : 53)
Query Neighborhood Hits	79	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NI77, Q86VS5, Q9H0F3	Gene names	KIF18A
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

IRF2_MOUSE
θ value	0.21417 (rank : 40)	NC score	0.023310 (rank : 39)
Query Neighborhood Hits	79	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

MDC1_MOUSE
θ value	0.47712 (rank : 41)	NC score	0.016841 (rank : 44)
Query Neighborhood Hits	79	Target Neighborhood Hits	998	Shared Neighborhood Hits	15
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ANGP2_MOUSE
θ value	1.06291 (rank : 42)	NC score	0.008207 (rank : 55)
Query Neighborhood Hits	79	Target Neighborhood Hits	397	Shared Neighborhood Hits	6
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

MYO3A_HUMAN
θ value	1.06291 (rank : 43)	NC score	-0.002345 (rank : 78)
Query Neighborhood Hits	79	Target Neighborhood Hits	1033	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

LAD1_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.016665 (rank : 45)
Query Neighborhood Hits	79	Target Neighborhood Hits	441	Shared Neighborhood Hits	10
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

DCP1A_MOUSE
θ value	2.36792 (rank : 45)	NC score	0.014503 (rank : 49)
Query Neighborhood Hits	79	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

HASP_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.016126 (rank : 47)
Query Neighborhood Hits	79	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0R0, Q99MU9, Q9JJJ4	Gene names	Gsg2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein).

LEO1_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.010970 (rank : 52)
Query Neighborhood Hits	79	Target Neighborhood Hits	958	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEUK_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.016115 (rank : 48)
Query Neighborhood Hits	79	Target Neighborhood Hits	213	Shared Neighborhood Hits	7
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

PAX3_MOUSE
θ value	2.36792 (rank : 49)	NC score	0.003317 (rank : 67)
Query Neighborhood Hits	79	Target Neighborhood Hits	478	Shared Neighborhood Hits	5
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

COLI_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.022303 (rank : 41)
Query Neighborhood Hits	79	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P01193, P01200, Q544U4	Gene names	Pomc, Pomc1
Domain Architecture
Description	Corticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC) [Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta- LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin].

CUTL1_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.001252 (rank : 72)
Query Neighborhood Hits	79	Target Neighborhood Hits	1574	Shared Neighborhood Hits	13
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

MAPK2_HUMAN
θ value	3.0926 (rank : 52)	NC score	-0.000705 (rank : 75)
Query Neighborhood Hits	79	Target Neighborhood Hits	844	Shared Neighborhood Hits	6
SwissProt Accessions	P49137, Q8IYD6	Gene names	MAPKAPK2
Domain Architecture
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

MAPK2_MOUSE
θ value	3.0926 (rank : 53)	NC score	-0.000682 (rank : 74)
Query Neighborhood Hits	79	Target Neighborhood Hits	831	Shared Neighborhood Hits	5
SwissProt Accessions	P49138, Q6P561	Gene names	Mapkapk2, Rps6kc1
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

CAD26_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.002042 (rank : 70)
Query Neighborhood Hits	79	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	P59862	Gene names	Cdh26
Domain Architecture
Description	Cadherin-like protein 26 precursor.

CN113_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.022341 (rank : 40)
Query Neighborhood Hits	79	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXV8	Gene names	C14orf113
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf113.

IRF2_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.016539 (rank : 46)
Query Neighborhood Hits	79	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

PAX3_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.002739 (rank : 68)
Query Neighborhood Hits	79	Target Neighborhood Hits	513	Shared Neighborhood Hits	5
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

DONS_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.011394 (rank : 51)
Query Neighborhood Hits	79	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXP4, Q80V93, Q8BV55	Gene names	Donson, ORF60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (Protein 3SG).

GLIS3_HUMAN
θ value	5.27518 (rank : 59)	NC score	-0.003657 (rank : 79)
Query Neighborhood Hits	79	Target Neighborhood Hits	758	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

SRRM2_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.013470 (rank : 50)
Query Neighborhood Hits	79	Target Neighborhood Hits	1296	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.017228 (rank : 43)
Query Neighborhood Hits	79	Target Neighborhood Hits	1470	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ATX2_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.008486 (rank : 54)
Query Neighborhood Hits	79	Target Neighborhood Hits	375	Shared Neighborhood Hits	9
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

COLI_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.017683 (rank : 42)
Query Neighborhood Hits	79	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P01189, P78442, Q9UD39, Q9UD40	Gene names	POMC
Domain Architecture
Description	Corticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC) [Contains: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin].

FXL19_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.007494 (rank : 56)
Query Neighborhood Hits	79	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

FZD5_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.003682 (rank : 65)
Query Neighborhood Hits	79	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD5_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.003695 (rank : 64)
Query Neighborhood Hits	79	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

KCNB1_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.001373 (rank : 71)
Query Neighborhood Hits	79	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

PTPRT_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.000356 (rank : 73)
Query Neighborhood Hits	79	Target Neighborhood Hits	219	Shared Neighborhood Hits	2
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

SP100_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.004543 (rank : 62)
Query Neighborhood Hits	79	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

ANKR6_HUMAN
θ value	8.99809 (rank : 70)	NC score	-0.000956 (rank : 77)
Query Neighborhood Hits	79	Target Neighborhood Hits	439	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

CA103_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.007298 (rank : 57)
Query Neighborhood Hits	79	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CDD9, Q8C893	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf103 homolog.

GPR97_MOUSE
θ value	8.99809 (rank : 72)	NC score	0.005422 (rank : 60)
Query Neighborhood Hits	79	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

KI67_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.005820 (rank : 59)
Query Neighborhood Hits	79	Target Neighborhood Hits	581	Shared Neighborhood Hits	9
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LIMA1_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.003468 (rank : 66)
Query Neighborhood Hits	79	Target Neighborhood Hits	298	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

LRRF2_HUMAN
θ value	8.99809 (rank : 75)	NC score	-0.000955 (rank : 76)
Query Neighborhood Hits	79	Target Neighborhood Hits	791	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

SETBP_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.006073 (rank : 58)
Query Neighborhood Hits	79	Target Neighborhood Hits	305	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SVIL_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.004238 (rank : 63)
Query Neighborhood Hits	79	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

TARA_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.005254 (rank : 61)
Query Neighborhood Hits	79	Target Neighborhood Hits	1626	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TGM3_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.002733 (rank : 69)
Query Neighborhood Hits	79	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q08189	Gene names	Tgm3, Tgase3
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase E precursor (EC 2.3.2.13) (TGase E) (TGE) (TG(E)) (Transglutaminase-3) [Contains: Protein- glutamine gamma-glutamyltransferase E 50 kDa non-catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa catalytic chain].

Hits sorted by NC score

PDE3A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	79	Target Neighborhood Hits	79	Shared Neighborhood Hits	79
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDE3A_MOUSE
NC score	0.993518 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	79	Target Neighborhood Hits	115	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z0X4	Gene names	Pde3a
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

PDE3B_HUMAN
NC score	0.986246 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	79	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q13370, O00639, Q14408	Gene names	PDE3B
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).

PDE1A_MOUSE
NC score	0.912732 (rank : 4)	θ value	1.97686e-47 (rank : 6)
Query Neighborhood Hits	79	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q61481, O35388	Gene names	Pde1a
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE).

PDE1A_HUMAN
NC score	0.912191 (rank : 5)	θ value	1.97686e-47 (rank : 5)
Query Neighborhood Hits	79	Target Neighborhood Hits	42	Shared Neighborhood Hits	38
SwissProt Accessions	P54750, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2, Q9C0L3, Q9C0L4, Q9UFX3	Gene names	PDE1A
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE) (hCam-1).

PDE1B_MOUSE
NC score	0.908470 (rank : 6)	θ value	8.04462e-41 (rank : 13)
Query Neighborhood Hits	79	Target Neighborhood Hits	46	Shared Neighborhood Hits	38
SwissProt Accessions	Q01065, O35384	Gene names	Pde1b, Pde1b1
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (EC 3.1.4.17) (Cam-PDE 1B) (63 kDa Cam-PDE).

PDE1B_HUMAN
NC score	0.907457 (rank : 7)	θ value	1.79215e-40 (rank : 14)
Query Neighborhood Hits	79	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	Q01064, Q92825	Gene names	PDE1B, PDE1B1
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (EC 3.1.4.17) (Cam-PDE 1B) (63 kDa Cam-PDE).

PDE1C_HUMAN
NC score	0.903226 (rank : 8)	θ value	2.85459e-46 (rank : 7)
Query Neighborhood Hits	79	Target Neighborhood Hits	134	Shared Neighborhood Hits	42
SwissProt Accessions	Q14123, Q14124	Gene names	PDE1C
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C) (hCam-3).

PDE1C_MOUSE
NC score	0.903157 (rank : 9)	θ value	1.51363e-47 (rank : 4)
Query Neighborhood Hits	79	Target Neighborhood Hits	161	Shared Neighborhood Hits	40
SwissProt Accessions	Q64338, Q62045, Q8BSV6	Gene names	Pde1c
Domain Architecture
Description	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (EC 3.1.4.17) (Cam-PDE 1C).

PDE4B_HUMAN
NC score	0.894942 (rank : 10)	θ value	1.91475e-42 (rank : 12)
Query Neighborhood Hits	79	Target Neighborhood Hits	65	Shared Neighborhood Hits	38
SwissProt Accessions	Q07343, O15443	Gene names	PDE4B
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.17) (DPDE4) (PDE32).

PDE4C_MOUSE
NC score	0.894584 (rank : 11)	θ value	7.52953e-39 (rank : 15)
Query Neighborhood Hits	79	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q3UEI1, Q8K0P4	Gene names	Pde4c
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17).

PDE4A_MOUSE
NC score	0.893722 (rank : 12)	θ value	6.58091e-43 (rank : 10)
Query Neighborhood Hits	79	Target Neighborhood Hits	66	Shared Neighborhood Hits	39
SwissProt Accessions	O89084, Q8R078, Q9JHQ4, Q9QX48, Q9QX49, Q9QXI8	Gene names	Pde4a
Domain Architecture
Description	cAMP-dependent 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17).

PDE4D_MOUSE
NC score	0.892901 (rank : 13)	θ value	1.73182e-43 (rank : 8)
Query Neighborhood Hits	79	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	Q01063, Q6TRH9, Q8C4Q7, Q8CG05	Gene names	Pde4d
Domain Architecture	No domain graphic available
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3).

PDE4A_HUMAN
NC score	0.892752 (rank : 14)	θ value	1.91475e-42 (rank : 11)
Query Neighborhood Hits	79	Target Neighborhood Hits	73	Shared Neighborhood Hits	38
SwissProt Accessions	P27815, O75522, O76092, Q16255, Q16691, Q8WUQ3	Gene names	PDE4A
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).

PDE4D_HUMAN
NC score	0.891950 (rank : 15)	θ value	3.85808e-43 (rank : 9)
Query Neighborhood Hits	79	Target Neighborhood Hits	122	Shared Neighborhood Hits	38
SwissProt Accessions	Q08499, O43433, Q13549, Q13550, Q13551, Q7Z2L8, Q8IV84, Q8IVA9, Q8IVD2, Q8IVD3, Q9HCX7	Gene names	PDE4D
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4D (EC 3.1.4.17) (DPDE3) (PDE43).

PDE4C_HUMAN
NC score	0.891430 (rank : 16)	θ value	1.6774e-38 (rank : 16)
Query Neighborhood Hits	79	Target Neighborhood Hits	56	Shared Neighborhood Hits	39
SwissProt Accessions	Q08493, Q9UN44, Q9UN45, Q9UN46, Q9UPJ6	Gene names	PDE4C
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4C (EC 3.1.4.17) (DPDE1) (PDE21).

PDE8B_HUMAN
NC score	0.888103 (rank : 17)	θ value	3.4976e-36 (rank : 17)
Query Neighborhood Hits	79	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95263, Q86XK8, Q8IUJ7, Q8IUJ8, Q8IUJ9, Q8IUK0, Q8N3T2	Gene names	PDE8B
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (EC 3.1.4.17) (HSPDE8B).

PDE7A_MOUSE
NC score	0.886794 (rank : 18)	θ value	3.74554e-30 (rank : 21)
Query Neighborhood Hits	79	Target Neighborhood Hits	39	Shared Neighborhood Hits	38
SwissProt Accessions	P70453, Q9ERB3	Gene names	Pde7a
Domain Architecture
Description	High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (EC 3.1.4.17) (P2A).

PDE7A_HUMAN
NC score	0.886066 (rank : 19)	θ value	2.19584e-30 (rank : 20)
Query Neighborhood Hits	79	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	Q13946, O15380	Gene names	PDE7A
Domain Architecture
Description	High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (EC 3.1.4.17) (HCP1) (TM22).

PDE8A_MOUSE
NC score	0.885095 (rank : 20)	θ value	6.59618e-35 (rank : 18)
Query Neighborhood Hits	79	Target Neighborhood Hits	52	Shared Neighborhood Hits	38
SwissProt Accessions	O88502	Gene names	Pde8a, Pde8
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17) (MMPDE8).

PDE8A_HUMAN
NC score	0.885040 (rank : 21)	θ value	3.27365e-34 (rank : 19)
Query Neighborhood Hits	79	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O60658, Q969I1, Q96PC9, Q96PD0, Q96PD1, Q9UMB7	Gene names	PDE8A
Domain Architecture
Description	High-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.17).

PDE7B_MOUSE
NC score	0.881010 (rank : 22)	θ value	8.63488e-27 (rank : 24)
Query Neighborhood Hits	79	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXQ1	Gene names	Pde7b
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 7B (EC 3.1.4.17).

PDE7B_HUMAN
NC score	0.878797 (rank : 23)	θ value	1.62847e-25 (rank : 25)
Query Neighborhood Hits	79	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP56	Gene names	PDE7B
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 7B (EC 3.1.4.17).

PDE9A_MOUSE
NC score	0.878117 (rank : 24)	θ value	2.05525e-28 (rank : 23)
Query Neighborhood Hits	79	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	O70628	Gene names	Pde9a, Pde8b
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDE9A_HUMAN
NC score	0.874453 (rank : 25)	θ value	1.57365e-28 (rank : 22)
Query Neighborhood Hits	79	Target Neighborhood Hits	93	Shared Neighborhood Hits	39
SwissProt Accessions	O76083, O75490, O75491, O95225, Q86SF7, Q86SI6, Q86SJ3, Q86WN3, Q86WN4, Q86WN5, Q86WN6, Q86WN7, Q86WN8, Q86WN9, Q86WP0	Gene names	PDE9A
Domain Architecture
Description	High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35).

PDE2A_MOUSE
NC score	0.792778 (rank : 26)	θ value	1.02238e-19 (rank : 27)
Query Neighborhood Hits	79	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	Q922S4, Q8K2U1	Gene names	Pde2a
Domain Architecture	No domain graphic available
Description	cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE).

PDE2A_HUMAN
NC score	0.791781 (rank : 27)	θ value	1.02238e-19 (rank : 26)
Query Neighborhood Hits	79	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O00408	Gene names	PDE2A
Domain Architecture
Description	cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE).

PDE11_HUMAN
NC score	0.765620 (rank : 28)	θ value	8.65492e-19 (rank : 28)
Query Neighborhood Hits	79	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCR9, Q53T16, Q96S76, Q9GZY7, Q9HB46, Q9NY45	Gene names	PDE11A
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

PDE11_MOUSE
NC score	0.764956 (rank : 29)	θ value	1.92812e-18 (rank : 29)
Query Neighborhood Hits	79	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	P0C1Q2	Gene names	Pde11a
Domain Architecture	No domain graphic available
Description	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.17) (EC 3.1.4.35) (cAMP and cGMP phosphodiesterase 11A).

PDE10_HUMAN
NC score	0.750970 (rank : 30)	θ value	2.98157e-11 (rank : 36)
Query Neighborhood Hits	79	Target Neighborhood Hits	49	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y233, Q9Y5T1	Gene names	PDE10A
Domain Architecture
Description	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (EC 3.1.4.17).

PDE5A_MOUSE
NC score	0.732189 (rank : 31)	θ value	2.52405e-10 (rank : 38)
Query Neighborhood Hits	79	Target Neighborhood Hits	50	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG03	Gene names	Pde5a, Pde5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

PDE5A_HUMAN
NC score	0.731002 (rank : 32)	θ value	2.98157e-11 (rank : 37)
Query Neighborhood Hits	79	Target Neighborhood Hits	48	Shared Neighborhood Hits	38
SwissProt Accessions	O76074, O75026, O75887, Q86UI0, Q86V66, Q9Y6Z6	Gene names	PDE5A, PDE5
Domain Architecture
Description	cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (CGB-PDE) (cGMP-binding cGMP-specific phosphodiesterase).

PDE6C_MOUSE
NC score	0.730291 (rank : 33)	θ value	8.95645e-16 (rank : 31)
Query Neighborhood Hits	79	Target Neighborhood Hits	45	Shared Neighborhood Hits	38
SwissProt Accessions	Q91ZQ1, Q8R0D4	Gene names	Pde6c
Domain Architecture	No domain graphic available
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PDE6C_HUMAN
NC score	0.730039 (rank : 34)	θ value	4.02038e-16 (rank : 30)
Query Neighborhood Hits	79	Target Neighborhood Hits	56	Shared Neighborhood Hits	39
SwissProt Accessions	P51160, Q5VY29	Gene names	PDE6C, PDEA2
Domain Architecture
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PDE6A_HUMAN
NC score	0.723404 (rank : 35)	θ value	2.20605e-14 (rank : 32)
Query Neighborhood Hits	79	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	P16499	Gene names	PDE6A, PDEA
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha) (PDE V-B1).

PDE6A_MOUSE
NC score	0.719786 (rank : 36)	θ value	4.91457e-14 (rank : 33)
Query Neighborhood Hits	79	Target Neighborhood Hits	45	Shared Neighborhood Hits	38
SwissProt Accessions	P27664	Gene names	Pde6a, Mpa, Pdea
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase alpha-subunit (EC 3.1.4.35) (GMP-PDE alpha).

PDE6B_HUMAN
NC score	0.719321 (rank : 37)	θ value	1.86753e-13 (rank : 34)
Query Neighborhood Hits	79	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	P35913, Q9BWH5	Gene names	PDE6B, PDEB
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase beta-subunit precursor (EC 3.1.4.35) (GMP-PDE beta).

PDE6B_MOUSE
NC score	0.714793 (rank : 38)	θ value	3.52202e-12 (rank : 35)
Query Neighborhood Hits	79	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	P23440	Gene names	Pde6b, Mpb, Pdeb, rd
Domain Architecture
Description	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta precursor (EC 3.1.4.35) (GMP-PDE beta).

IRF2_MOUSE
NC score	0.023310 (rank : 39)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	79	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P23906	Gene names	Irf2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

CN113_HUMAN
NC score	0.022341 (rank : 40)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	79	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXV8	Gene names	C14orf113
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf113.

COLI_MOUSE
NC score	0.022303 (rank : 41)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	79	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P01193, P01200, Q544U4	Gene names	Pomc, Pomc1
Domain Architecture
Description	Corticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC) [Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta- LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin].

COLI_HUMAN
NC score	0.017683 (rank : 42)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	79	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P01189, P78442, Q9UD39, Q9UD40	Gene names	POMC
Domain Architecture
Description	Corticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC) [Contains: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin].

SRRM2_MOUSE
NC score	0.017228 (rank : 43)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	79	Target Neighborhood Hits	1470	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MDC1_MOUSE
NC score	0.016841 (rank : 44)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	79	Target Neighborhood Hits	998	Shared Neighborhood Hits	15
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

LAD1_HUMAN
NC score	0.016665 (rank : 45)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	79	Target Neighborhood Hits	441	Shared Neighborhood Hits	10
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

IRF2_HUMAN
NC score	0.016539 (rank : 46)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	79	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P14316, Q96B99	Gene names	IRF2
Domain Architecture
Description	Interferon regulatory factor 2 (IRF-2).

HASP_MOUSE
NC score	0.016126 (rank : 47)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	79	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0R0, Q99MU9, Q9JJJ4	Gene names	Gsg2
Domain Architecture
Description	Serine/threonine-protein kinase Haspin (EC 2.7.11.1) (Haploid germ cell-specific nuclear protein kinase) (Germ cell-specific gene 2 protein).

LEUK_HUMAN
NC score	0.016115 (rank : 48)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	79	Target Neighborhood Hits	213	Shared Neighborhood Hits	7
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

DCP1A_MOUSE
NC score	0.014503 (rank : 49)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	79	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

SRRM2_HUMAN
NC score	0.013470 (rank : 50)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	79	Target Neighborhood Hits	1296	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DONS_MOUSE
NC score	0.011394 (rank : 51)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	79	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXP4, Q80V93, Q8BV55	Gene names	Donson, ORF60
Domain Architecture	No domain graphic available
Description	Protein downstream neighbor of Son (Protein 3SG).

LEO1_HUMAN
NC score	0.010970 (rank : 52)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	79	Target Neighborhood Hits	958	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

KI18A_HUMAN
NC score	0.009098 (rank : 53)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	79	Target Neighborhood Hits	168	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NI77, Q86VS5, Q9H0F3	Gene names	KIF18A
Domain Architecture	No domain graphic available
Description	Kinesin family member 18A.

ATX2_HUMAN
NC score	0.008486 (rank : 54)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	79	Target Neighborhood Hits	375	Shared Neighborhood Hits	9
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

ANGP2_MOUSE
NC score	0.008207 (rank : 55)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	79	Target Neighborhood Hits	397	Shared Neighborhood Hits	6
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

FXL19_MOUSE
NC score	0.007494 (rank : 56)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	79	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

CA103_MOUSE
NC score	0.007298 (rank : 57)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	79	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CDD9, Q8C893	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf103 homolog.

SETBP_HUMAN
NC score	0.006073 (rank : 58)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	79	Target Neighborhood Hits	305	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y6X0, Q9UEF3	Gene names	SETBP1, KIAA0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

KI67_HUMAN
NC score	0.005820 (rank : 59)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	79	Target Neighborhood Hits	581	Shared Neighborhood Hits	9
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

GPR97_MOUSE
NC score	0.005422 (rank : 60)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	79	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

TARA_HUMAN
NC score	0.005254 (rank : 61)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	79	Target Neighborhood Hits	1626	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SP100_HUMAN
NC score	0.004543 (rank : 62)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	79	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

SVIL_HUMAN
NC score	0.004238 (rank : 63)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	79	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	O95425, O60611, O60612, Q5VZK5, Q5VZK6, Q9H1R7	Gene names	SVIL
Domain Architecture	No domain graphic available
Description	Supervillin (Archvillin) (p205/p250).

FZD5_MOUSE
NC score	0.003695 (rank : 64)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	79	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD5_HUMAN
NC score	0.003682 (rank : 65)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	79	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

LIMA1_MOUSE
NC score	0.003468 (rank : 66)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	79	Target Neighborhood Hits	298	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERG0, Q9ERG1	Gene names	Lima1, D15Ertd366e, Eplin
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm) (mEPLIN).

PAX3_MOUSE
NC score	0.003317 (rank : 67)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	79	Target Neighborhood Hits	478	Shared Neighborhood Hits	5
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

PAX3_HUMAN
NC score	0.002739 (rank : 68)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	79	Target Neighborhood Hits	513	Shared Neighborhood Hits	5
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

TGM3_MOUSE
NC score	0.002733 (rank : 69)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	79	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q08189	Gene names	Tgm3, Tgase3
Domain Architecture
Description	Protein-glutamine gamma-glutamyltransferase E precursor (EC 2.3.2.13) (TGase E) (TGE) (TG(E)) (Transglutaminase-3) [Contains: Protein- glutamine gamma-glutamyltransferase E 50 kDa non-catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa catalytic chain].

CAD26_MOUSE
NC score	0.002042 (rank : 70)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	79	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	P59862	Gene names	Cdh26
Domain Architecture
Description	Cadherin-like protein 26 precursor.

KCNB1_HUMAN
NC score	0.001373 (rank : 71)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	79	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

CUTL1_HUMAN
NC score	0.001252 (rank : 72)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	79	Target Neighborhood Hits	1574	Shared Neighborhood Hits	13
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

PTPRT_MOUSE
NC score	0.000356 (rank : 73)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	79	Target Neighborhood Hits	219	Shared Neighborhood Hits	2
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

MAPK2_MOUSE
NC score	-0.000682 (rank : 74)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	79	Target Neighborhood Hits	831	Shared Neighborhood Hits	5
SwissProt Accessions	P49138, Q6P561	Gene names	Mapkapk2, Rps6kc1
Domain Architecture	No domain graphic available
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

MAPK2_HUMAN
NC score	-0.000705 (rank : 75)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	79	Target Neighborhood Hits	844	Shared Neighborhood Hits	6
SwissProt Accessions	P49137, Q8IYD6	Gene names	MAPKAPK2
Domain Architecture
Description	MAP kinase-activated protein kinase 2 (EC 2.7.11.1) (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAPK-2) (MK2).

LRRF2_HUMAN
NC score	-0.000955 (rank : 76)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	79	Target Neighborhood Hits	791	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

ANKR6_HUMAN
NC score	-0.000956 (rank : 77)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	79	Target Neighborhood Hits	439	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

MYO3A_HUMAN
NC score	-0.002345 (rank : 78)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	79	Target Neighborhood Hits	1033	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

GLIS3_HUMAN
NC score	-0.003657 (rank : 79)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	79	Target Neighborhood Hits	758	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).