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Network neighborhood for query Sequence : FZD5_HUMAN

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FZD5_HUMAN
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FZD5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD5_MOUSE
θ value	0 (rank : 2)	NC score	0.999469 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	70	Shared Neighborhood Hits	62
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD8_HUMAN
θ value	3.16172e-154 (rank : 3)	NC score	0.992418 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	88	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD8_MOUSE
θ value	1.56915e-153 (rank : 4)	NC score	0.992448 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FZD2_MOUSE
θ value	1.24331e-150 (rank : 5)	NC score	0.989029 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD2_HUMAN
θ value	3.06238e-149 (rank : 6)	NC score	0.989095 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	57	Shared Neighborhood Hits	45
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD7_MOUSE
θ value	8.91014e-149 (rank : 7)	NC score	0.990091 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	59	Shared Neighborhood Hits	45
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD7_HUMAN
θ value	3.38586e-148 (rank : 8)	NC score	0.990138 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	56	Shared Neighborhood Hits	43
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD1_HUMAN
θ value	2.2711e-144 (rank : 9)	NC score	0.988373 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	62	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD1_MOUSE
θ value	5.23575e-141 (rank : 10)	NC score	0.988334 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	63	Shared Neighborhood Hits	50
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD10_MOUSE
θ value	2.69525e-129 (rank : 11)	NC score	0.987556 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	56	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

FZD10_HUMAN
θ value	1.05987e-125 (rank : 12)	NC score	0.987863 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	51	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD4_MOUSE
θ value	1.43246e-122 (rank : 13)	NC score	0.987385 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

FZD4_HUMAN
θ value	1.87085e-122 (rank : 14)	NC score	0.987481 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	54	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

FZD9_MOUSE
θ value	4.16784e-122 (rank : 15)	NC score	0.986906 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	66	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

FZD9_HUMAN
θ value	7.35691e-119 (rank : 16)	NC score	0.986885 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	63	Shared Neighborhood Hits	48
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD3_HUMAN
θ value	7.15887e-98 (rank : 17)	NC score	0.969255 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	74	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD3_MOUSE
θ value	7.15887e-98 (rank : 18)	NC score	0.969402 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	75	Shared Neighborhood Hits	47
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

FZD6_HUMAN
θ value	1.35324e-88 (rank : 19)	NC score	0.969613 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

FZD6_MOUSE
θ value	3.44927e-84 (rank : 20)	NC score	0.966284 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	135	Shared Neighborhood Hits	46
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

SMO_HUMAN
θ value	4.86918e-46 (rank : 21)	NC score	0.892620 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

SMO_MOUSE
θ value	4.55743e-44 (rank : 22)	NC score	0.888241 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

SFRP3_HUMAN
θ value	4.00176e-32 (rank : 23)	NC score	0.871251 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP3_MOUSE
θ value	4.00176e-32 (rank : 24)	NC score	0.871785 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP4_HUMAN
θ value	9.8567e-31 (rank : 25)	NC score	0.880278 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP4_MOUSE
θ value	9.8567e-31 (rank : 26)	NC score	0.879858 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SFRP5_MOUSE
θ value	3.39556e-23 (rank : 27)	NC score	0.833962 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

SFRP5_HUMAN
θ value	9.87957e-23 (rank : 28)	NC score	0.833512 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP2_HUMAN
θ value	3.17815e-21 (rank : 29)	NC score	0.826205 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

SFRP2_MOUSE
θ value	3.17815e-21 (rank : 30)	NC score	0.827207 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP1_MOUSE
θ value	8.65492e-19 (rank : 31)	NC score	0.829570 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP1_HUMAN
θ value	1.92812e-18 (rank : 32)	NC score	0.829051 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

CORIN_HUMAN
θ value	8.10077e-17 (rank : 33)	NC score	0.286103 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	453	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	1.80466e-16 (rank : 34)	NC score	0.285941 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	451	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

MFRP_HUMAN
θ value	1.33837e-11 (rank : 35)	NC score	0.439190 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	3.89403e-11 (rank : 36)	NC score	0.444413 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	166	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPZ_HUMAN
θ value	2.79066e-09 (rank : 37)	NC score	0.425278 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
θ value	8.97725e-08 (rank : 38)	NC score	0.379888 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

COIA1_MOUSE
θ value	1.53129e-07 (rank : 39)	NC score	0.263011 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	481	Shared Neighborhood Hits	37
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CELR1_MOUSE
θ value	0.0113563 (rank : 40)	NC score	0.029999 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	617	Shared Neighborhood Hits	31
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

GP126_HUMAN
θ value	0.0736092 (rank : 41)	NC score	0.067203 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	187	Shared Neighborhood Hits	31
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

CELR1_HUMAN
θ value	0.163984 (rank : 42)	NC score	0.019016 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	613	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

GPR64_MOUSE
θ value	0.163984 (rank : 43)	NC score	0.053658 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	156	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

BAI1_HUMAN
θ value	0.21417 (rank : 44)	NC score	0.053857 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	375	Shared Neighborhood Hits	28
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

GPR64_HUMAN
θ value	0.279714 (rank : 45)	NC score	0.051609 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	207	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GP144_HUMAN
θ value	0.365318 (rank : 46)	NC score	0.036285 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	108	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

BAI1_MOUSE
θ value	0.62314 (rank : 47)	NC score	0.048955 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	340	Shared Neighborhood Hits	25
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

GP174_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.005018 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	486	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BXC1	Gene names	GPR174
Domain Architecture
Description	Probable G-protein coupled receptor 174.

GP174_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.004954 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	480	Shared Neighborhood Hits	9
SwissProt Accessions	Q3U507	Gene names	Gpr174, Gm376
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 174.

MAL_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.025223 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	O09198, O08819, O09109	Gene names	Mal
Domain Architecture
Description	Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein).

BAI3_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.046170 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	246	Shared Neighborhood Hits	25
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.046048 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	250	Shared Neighborhood Hits	25
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

MAL_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.022734 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P21145	Gene names	MAL
Domain Architecture
Description	Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein).

CLD13_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.011015 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0S4	Gene names	Cldn13
Domain Architecture
Description	Claudin-13.

LRFN3_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.001959 (rank : 75)
Query Neighborhood Hits	71	Target Neighborhood Hits	444	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN3_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.001848 (rank : 76)
Query Neighborhood Hits	71	Target Neighborhood Hits	455	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

SFT2A_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.031568 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WV19, Q5TI64, Q9UIC7	Gene names	SFT2D1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) (pRGR1).

ATX7_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.007793 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

EDG3_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.010773 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	860	Shared Neighborhood Hits	9
SwissProt Accessions	Q99500, Q7Z5I2	Gene names	EDG3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3).

EDG3_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.005978 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	861	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0U9, Q8BP20	Gene names	Edg3, Lpb3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3).

EDG6_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.006648 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	462	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0L1, Q3U4H3, Q8C6E2, Q8K1R9	Gene names	Edg6, Lpc1, S1p4
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-6 (S1P receptor Edg-6) (Endothelial differentiation G-protein coupled receptor 6) (Lysophospholipid receptor C1) (Sphingosine 1-phosphate receptor 4) (S1P4).

TYSY_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.015460 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P07607	Gene names	Tyms
Domain Architecture
Description	Thymidylate synthase (EC 2.1.1.45) (TS) (TSase).

ELTD1_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.020290 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

GP112_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.044605 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP157_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.166271 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

PDE3A_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.003682 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

SFT2A_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.026103 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SSN7	Gene names	Sft2d1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1).

TYSY_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.011341 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P04818	Gene names	TYMS, TS
Domain Architecture
Description	Thymidylate synthase (EC 2.1.1.45) (TS) (TSase).

ELTD1_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.016678 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

FRAT1_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.004674 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q92837, Q8NE74, Q8TDW9	Gene names	FRAT1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

LPHN1_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.019341 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	155	Shared Neighborhood Hits	15
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

BAI2_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.054478 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	332	Shared Neighborhood Hits	29
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.054563 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	323	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.071754 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	115	Shared Neighborhood Hits	31
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP155_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.116741 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

GP157_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.155546 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

Hits sorted by NC score

FZD5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD5_MOUSE
NC score	0.999469 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	70	Shared Neighborhood Hits	62
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD8_MOUSE
NC score	0.992448 (rank : 3)	θ value	1.56915e-153 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FZD8_HUMAN
NC score	0.992418 (rank : 4)	θ value	3.16172e-154 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	88	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD7_HUMAN
NC score	0.990138 (rank : 5)	θ value	3.38586e-148 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	56	Shared Neighborhood Hits	43
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD7_MOUSE
NC score	0.990091 (rank : 6)	θ value	8.91014e-149 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	59	Shared Neighborhood Hits	45
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD2_HUMAN
NC score	0.989095 (rank : 7)	θ value	3.06238e-149 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	57	Shared Neighborhood Hits	45
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD2_MOUSE
NC score	0.989029 (rank : 8)	θ value	1.24331e-150 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD1_HUMAN
NC score	0.988373 (rank : 9)	θ value	2.2711e-144 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	62	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD1_MOUSE
NC score	0.988334 (rank : 10)	θ value	5.23575e-141 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	63	Shared Neighborhood Hits	50
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD10_HUMAN
NC score	0.987863 (rank : 11)	θ value	1.05987e-125 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	51	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD10_MOUSE
NC score	0.987556 (rank : 12)	θ value	2.69525e-129 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	56	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

FZD4_HUMAN
NC score	0.987481 (rank : 13)	θ value	1.87085e-122 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	54	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

FZD4_MOUSE
NC score	0.987385 (rank : 14)	θ value	1.43246e-122 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

FZD9_MOUSE
NC score	0.986906 (rank : 15)	θ value	4.16784e-122 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	66	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

FZD9_HUMAN
NC score	0.986885 (rank : 16)	θ value	7.35691e-119 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	63	Shared Neighborhood Hits	48
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD6_HUMAN
NC score	0.969613 (rank : 17)	θ value	1.35324e-88 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

FZD3_MOUSE
NC score	0.969402 (rank : 18)	θ value	7.15887e-98 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	75	Shared Neighborhood Hits	47
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

FZD3_HUMAN
NC score	0.969255 (rank : 19)	θ value	7.15887e-98 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	74	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD6_MOUSE
NC score	0.966284 (rank : 20)	θ value	3.44927e-84 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	135	Shared Neighborhood Hits	46
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

SMO_HUMAN
NC score	0.892620 (rank : 21)	θ value	4.86918e-46 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

SMO_MOUSE
NC score	0.888241 (rank : 22)	θ value	4.55743e-44 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

SFRP4_HUMAN
NC score	0.880278 (rank : 23)	θ value	9.8567e-31 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP4_MOUSE
NC score	0.879858 (rank : 24)	θ value	9.8567e-31 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SFRP3_MOUSE
NC score	0.871785 (rank : 25)	θ value	4.00176e-32 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP3_HUMAN
NC score	0.871251 (rank : 26)	θ value	4.00176e-32 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP5_MOUSE
NC score	0.833962 (rank : 27)	θ value	3.39556e-23 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

SFRP5_HUMAN
NC score	0.833512 (rank : 28)	θ value	9.87957e-23 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP1_MOUSE
NC score	0.829570 (rank : 29)	θ value	8.65492e-19 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP1_HUMAN
NC score	0.829051 (rank : 30)	θ value	1.92812e-18 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP2_MOUSE
NC score	0.827207 (rank : 31)	θ value	3.17815e-21 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP2_HUMAN
NC score	0.826205 (rank : 32)	θ value	3.17815e-21 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

MFRP_MOUSE
NC score	0.444413 (rank : 33)	θ value	3.89403e-11 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	166	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_HUMAN
NC score	0.439190 (rank : 34)	θ value	1.33837e-11 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPZ_HUMAN
NC score	0.425278 (rank : 35)	θ value	2.79066e-09 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
NC score	0.379888 (rank : 36)	θ value	8.97725e-08 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CORIN_HUMAN
NC score	0.286103 (rank : 37)	θ value	8.10077e-17 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	453	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
NC score	0.285941 (rank : 38)	θ value	1.80466e-16 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	451	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

COIA1_MOUSE
NC score	0.263011 (rank : 39)	θ value	1.53129e-07 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	481	Shared Neighborhood Hits	37
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GP157_HUMAN
NC score	0.166271 (rank : 40)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP157_MOUSE
NC score	0.155546 (rank : 41)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	71	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP155_HUMAN
NC score	0.116741 (rank : 42)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	71	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

GP133_HUMAN
NC score	0.071754 (rank : 43)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	115	Shared Neighborhood Hits	31
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP126_HUMAN
NC score	0.067203 (rank : 44)	θ value	0.0736092 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	187	Shared Neighborhood Hits	31
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

BAI2_MOUSE
NC score	0.054563 (rank : 45)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	323	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
NC score	0.054478 (rank : 46)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	332	Shared Neighborhood Hits	29
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI1_HUMAN
NC score	0.053857 (rank : 47)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	375	Shared Neighborhood Hits	28
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

GPR64_MOUSE
NC score	0.053658 (rank : 48)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	156	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR64_HUMAN
NC score	0.051609 (rank : 49)	θ value	0.279714 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	207	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

BAI1_MOUSE
NC score	0.048955 (rank : 50)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	340	Shared Neighborhood Hits	25
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI3_HUMAN
NC score	0.046170 (rank : 51)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	246	Shared Neighborhood Hits	25
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
NC score	0.046048 (rank : 52)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	250	Shared Neighborhood Hits	25
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

GP112_HUMAN
NC score	0.044605 (rank : 53)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP144_HUMAN
NC score	0.036285 (rank : 54)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	108	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

SFT2A_HUMAN
NC score	0.031568 (rank : 55)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WV19, Q5TI64, Q9UIC7	Gene names	SFT2D1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) (pRGR1).

CELR1_MOUSE
NC score	0.029999 (rank : 56)	θ value	0.0113563 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	617	Shared Neighborhood Hits	31
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

SFT2A_MOUSE
NC score	0.026103 (rank : 57)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SSN7	Gene names	Sft2d1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1).

MAL_MOUSE
NC score	0.025223 (rank : 58)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	O09198, O08819, O09109	Gene names	Mal
Domain Architecture
Description	Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein).

MAL_HUMAN
NC score	0.022734 (rank : 59)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P21145	Gene names	MAL
Domain Architecture
Description	Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein).

ELTD1_HUMAN
NC score	0.020290 (rank : 60)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

LPHN1_HUMAN
NC score	0.019341 (rank : 61)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	155	Shared Neighborhood Hits	15
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

CELR1_HUMAN
NC score	0.019016 (rank : 62)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	613	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

ELTD1_MOUSE
NC score	0.016678 (rank : 63)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

TYSY_MOUSE
NC score	0.015460 (rank : 64)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P07607	Gene names	Tyms
Domain Architecture
Description	Thymidylate synthase (EC 2.1.1.45) (TS) (TSase).

TYSY_HUMAN
NC score	0.011341 (rank : 65)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P04818	Gene names	TYMS, TS
Domain Architecture
Description	Thymidylate synthase (EC 2.1.1.45) (TS) (TSase).

CLD13_MOUSE
NC score	0.011015 (rank : 66)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0S4	Gene names	Cldn13
Domain Architecture
Description	Claudin-13.

EDG3_HUMAN
NC score	0.010773 (rank : 67)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	860	Shared Neighborhood Hits	9
SwissProt Accessions	Q99500, Q7Z5I2	Gene names	EDG3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3).

ATX7_MOUSE
NC score	0.007793 (rank : 68)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

EDG6_MOUSE
NC score	0.006648 (rank : 69)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	462	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0L1, Q3U4H3, Q8C6E2, Q8K1R9	Gene names	Edg6, Lpc1, S1p4
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-6 (S1P receptor Edg-6) (Endothelial differentiation G-protein coupled receptor 6) (Lysophospholipid receptor C1) (Sphingosine 1-phosphate receptor 4) (S1P4).

EDG3_MOUSE
NC score	0.005978 (rank : 70)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	861	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0U9, Q8BP20	Gene names	Edg3, Lpb3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3).

GP174_HUMAN
NC score	0.005018 (rank : 71)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	486	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BXC1	Gene names	GPR174
Domain Architecture
Description	Probable G-protein coupled receptor 174.

GP174_MOUSE
NC score	0.004954 (rank : 72)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	480	Shared Neighborhood Hits	9
SwissProt Accessions	Q3U507	Gene names	Gpr174, Gm376
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 174.

FRAT1_HUMAN
NC score	0.004674 (rank : 73)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q92837, Q8NE74, Q8TDW9	Gene names	FRAT1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

PDE3A_HUMAN
NC score	0.003682 (rank : 74)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q14432, O60865, Q13348	Gene names	PDE3A
Domain Architecture
Description	cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A).

LRFN3_HUMAN
NC score	0.001959 (rank : 75)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	444	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN3_MOUSE
NC score	0.001848 (rank : 76)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	455	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.