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Network neighborhood for query Sequence : FZD8_MOUSE

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FZD8_MOUSE
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FZD8_HUMAN
θ value	0 (rank : 1)	NC score	0.998000 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	88	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD8_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FZD5_HUMAN
θ value	1.56915e-153 (rank : 3)	NC score	0.992448 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	71	Shared Neighborhood Hits	51
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD5_MOUSE
θ value	5.96274e-153 (rank : 4)	NC score	0.992599 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD7_MOUSE
θ value	5.9766e-145 (rank : 5)	NC score	0.986336 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD7_HUMAN
θ value	1.92261e-143 (rank : 6)	NC score	0.986335 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD10_MOUSE
θ value	3.76964e-123 (rank : 7)	NC score	0.986466 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	56	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

FZD10_HUMAN
θ value	2.06847e-121 (rank : 8)	NC score	0.986856 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	51	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD4_MOUSE
θ value	4.60808e-121 (rank : 9)	NC score	0.986119 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

FZD4_HUMAN
θ value	1.75107e-120 (rank : 10)	NC score	0.986239 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	54	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

FZD2_HUMAN
θ value	2.07809e-105 (rank : 11)	NC score	0.983482 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD2_MOUSE
θ value	2.07809e-105 (rank : 12)	NC score	0.983348 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD9_MOUSE
θ value	5.11853e-104 (rank : 13)	NC score	0.984885 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	66	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

FZD1_HUMAN
θ value	9.65309e-103 (rank : 14)	NC score	0.982410 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	62	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD9_HUMAN
θ value	3.66817e-102 (rank : 15)	NC score	0.984866 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	63	Shared Neighborhood Hits	46
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD1_MOUSE
θ value	7.64859e-100 (rank : 16)	NC score	0.981844 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	63	Shared Neighborhood Hits	48
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD6_MOUSE
θ value	6.52014e-75 (rank : 17)	NC score	0.959227 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	135	Shared Neighborhood Hits	47
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

FZD3_HUMAN
θ value	1.66191e-70 (rank : 18)	NC score	0.960435 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD3_MOUSE
θ value	2.83479e-70 (rank : 19)	NC score	0.960567 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	75	Shared Neighborhood Hits	45
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

FZD6_HUMAN
θ value	1.07722e-69 (rank : 20)	NC score	0.962618 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	84	Shared Neighborhood Hits	47
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

SMO_HUMAN
θ value	3.37985e-39 (rank : 21)	NC score	0.885222 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

SMO_MOUSE
θ value	5.76516e-39 (rank : 22)	NC score	0.880820 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

SFRP3_MOUSE
θ value	2.42779e-29 (rank : 23)	NC score	0.872220 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP3_HUMAN
θ value	5.40856e-29 (rank : 24)	NC score	0.871653 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP4_HUMAN
θ value	5.06226e-27 (rank : 25)	NC score	0.879750 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP4_MOUSE
θ value	5.06226e-27 (rank : 26)	NC score	0.879442 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SFRP2_HUMAN
θ value	2.59989e-23 (rank : 27)	NC score	0.835366 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

SFRP2_MOUSE
θ value	2.59989e-23 (rank : 28)	NC score	0.836273 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP5_MOUSE
θ value	2.20094e-22 (rank : 29)	NC score	0.840417 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

SFRP5_HUMAN
θ value	6.40375e-22 (rank : 30)	NC score	0.840027 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP1_MOUSE
θ value	6.62687e-19 (rank : 31)	NC score	0.836423 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP1_HUMAN
θ value	8.65492e-19 (rank : 32)	NC score	0.835980 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

CORIN_MOUSE
θ value	3.28887e-18 (rank : 33)	NC score	0.289346 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	451	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CORIN_HUMAN
θ value	7.32683e-18 (rank : 34)	NC score	0.289132 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	453	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

MFRP_HUMAN
θ value	1.02475e-11 (rank : 35)	NC score	0.440885 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	1.133e-10 (rank : 36)	NC score	0.445663 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPZ_HUMAN
θ value	3.64472e-09 (rank : 37)	NC score	0.427143 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

COIA1_MOUSE
θ value	5.26297e-08 (rank : 38)	NC score	0.268024 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	481	Shared Neighborhood Hits	45
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CBPZ_MOUSE
θ value	1.53129e-07 (rank : 39)	NC score	0.381836 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

EDG3_HUMAN
θ value	0.000270298 (rank : 40)	NC score	0.017935 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	860	Shared Neighborhood Hits	8
SwissProt Accessions	Q99500, Q7Z5I2	Gene names	EDG3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3).

TP53B_HUMAN
θ value	0.0148317 (rank : 41)	NC score	0.056513 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	413	Shared Neighborhood Hits	9
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TP53B_MOUSE
θ value	0.0330416 (rank : 42)	NC score	0.045056 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	644	Shared Neighborhood Hits	11
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CELR1_MOUSE
θ value	0.0431538 (rank : 43)	NC score	0.028755 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	617	Shared Neighborhood Hits	27
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

SLIK1_MOUSE
θ value	0.0736092 (rank : 44)	NC score	0.012957 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	333	Shared Neighborhood Hits	5
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

RGS3_HUMAN
θ value	0.0961366 (rank : 45)	NC score	0.008455 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	1375	Shared Neighborhood Hits	14
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

EDG3_MOUSE
θ value	0.125558 (rank : 46)	NC score	0.012173 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	861	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0U9, Q8BP20	Gene names	Edg3, Lpb3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3).

CELR3_MOUSE
θ value	0.21417 (rank : 47)	NC score	0.023486 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	687	Shared Neighborhood Hits	28
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

GP126_HUMAN
θ value	0.21417 (rank : 48)	NC score	0.059144 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	187	Shared Neighborhood Hits	26
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

SMBP2_HUMAN
θ value	0.279714 (rank : 49)	NC score	0.014408 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

GP157_HUMAN
θ value	0.365318 (rank : 50)	NC score	0.178295 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

LPHN3_HUMAN
θ value	0.365318 (rank : 51)	NC score	0.041989 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	139	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

GP157_MOUSE
θ value	0.62314 (rank : 52)	NC score	0.167310 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GPR64_HUMAN
θ value	0.62314 (rank : 53)	NC score	0.043281 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	207	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

NACAM_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.003898 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	1866	Shared Neighborhood Hits	21
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SLIK1_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.012232 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

RIN3_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.013303 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

CELR1_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.017863 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	613	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR3_HUMAN
θ value	1.06291 (rank : 58)	NC score	0.019292 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	680	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CF195_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.028466 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MT4, Q5TAW4	Gene names	C6orf195
Domain Architecture	No domain graphic available
Description	Protein C6orf195.

DIDO1_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.009670 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	960	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GP174_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.006180 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	486	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXC1	Gene names	GPR174
Domain Architecture
Description	Probable G-protein coupled receptor 174.

RNF5_MOUSE
θ value	1.38821 (rank : 62)	NC score	0.013522 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

SFT2A_HUMAN
θ value	1.38821 (rank : 63)	NC score	0.036713 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WV19, Q5TI64, Q9UIC7	Gene names	SFT2D1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) (pRGR1).

GP174_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.005982 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	480	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U507	Gene names	Gpr174, Gm376
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 174.

SFT2A_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.031696 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SSN7	Gene names	Sft2d1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1).

TMM28_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.027744 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O75949	Gene names	TMEM28, TED
Domain Architecture	No domain graphic available
Description	Transmembrane protein 28 (TED protein).

LCP2_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.005512 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	531	Shared Neighborhood Hits	7
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

NOTC3_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.001997 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	1062	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ZFP28_HUMAN
θ value	3.0926 (rank : 69)	NC score	-0.004989 (rank : 91)
Query Neighborhood Hits	89	Target Neighborhood Hits	843	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

CD2_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.009321 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	504	Shared Neighborhood Hits	9
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

JIP2_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.008680 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	288	Shared Neighborhood Hits	7
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

RNF5_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.009016 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

SC6A4_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.002394 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q60857, O35241	Gene names	Slc6a4, Htt, Sert
Domain Architecture
Description	Sodium-dependent serotonin transporter (5HT transporter) (5HTT).

SOX13_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.002044 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	464	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

ZN385_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.009209 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	614	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ADA19_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.001284 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	381	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

GPR64_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.043645 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

LIMD1_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.001892 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

RPGF1_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.005142 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SEM6C_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.001404 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	352	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

TRXR1_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.012496 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q16881, Q76P53, Q7LA96, Q9UH79	Gene names	TXNRD1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic precursor (EC 1.8.1.9) (TR) (TR1).

HXC11_HUMAN
θ value	6.88961 (rank : 82)	NC score	-0.001268 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	349	Shared Neighborhood Hits	4
SwissProt Accessions	O43248, Q96DH2	Gene names	HOXC11
Domain Architecture
Description	Homeobox protein Hox-C11.

K0310_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.007484 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	420	Shared Neighborhood Hits	7
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

CI079_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.005874 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	288	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

NCOR2_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.002819 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	790	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NMD3A_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.003024 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

S23IP_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.004259 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	363	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SC6A4_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.002628 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P31645	Gene names	SLC6A4, HTT, SERT
Domain Architecture
Description	Sodium-dependent serotonin transporter (5HT transporter) (5HTT).

TR19L_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.005159 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

GP133_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.064151 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	115	Shared Neighborhood Hits	26
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP155_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.111101 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

Hits sorted by NC score

FZD8_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FZD8_HUMAN
NC score	0.998000 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	88	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD5_MOUSE
NC score	0.992599 (rank : 3)	θ value	5.96274e-153 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD5_HUMAN
NC score	0.992448 (rank : 4)	θ value	1.56915e-153 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	71	Shared Neighborhood Hits	51
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD10_HUMAN
NC score	0.986856 (rank : 5)	θ value	2.06847e-121 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	51	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD10_MOUSE
NC score	0.986466 (rank : 6)	θ value	3.76964e-123 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	56	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

FZD7_MOUSE
NC score	0.986336 (rank : 7)	θ value	5.9766e-145 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD7_HUMAN
NC score	0.986335 (rank : 8)	θ value	1.92261e-143 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD4_HUMAN
NC score	0.986239 (rank : 9)	θ value	1.75107e-120 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	54	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

FZD4_MOUSE
NC score	0.986119 (rank : 10)	θ value	4.60808e-121 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

FZD9_MOUSE
NC score	0.984885 (rank : 11)	θ value	5.11853e-104 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	66	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

FZD9_HUMAN
NC score	0.984866 (rank : 12)	θ value	3.66817e-102 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	63	Shared Neighborhood Hits	46
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD2_HUMAN
NC score	0.983482 (rank : 13)	θ value	2.07809e-105 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD2_MOUSE
NC score	0.983348 (rank : 14)	θ value	2.07809e-105 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD1_HUMAN
NC score	0.982410 (rank : 15)	θ value	9.65309e-103 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	62	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD1_MOUSE
NC score	0.981844 (rank : 16)	θ value	7.64859e-100 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	63	Shared Neighborhood Hits	48
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD6_HUMAN
NC score	0.962618 (rank : 17)	θ value	1.07722e-69 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	84	Shared Neighborhood Hits	47
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

FZD3_MOUSE
NC score	0.960567 (rank : 18)	θ value	2.83479e-70 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	75	Shared Neighborhood Hits	45
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

FZD3_HUMAN
NC score	0.960435 (rank : 19)	θ value	1.66191e-70 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD6_MOUSE
NC score	0.959227 (rank : 20)	θ value	6.52014e-75 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	135	Shared Neighborhood Hits	47
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

SMO_HUMAN
NC score	0.885222 (rank : 21)	θ value	3.37985e-39 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

SMO_MOUSE
NC score	0.880820 (rank : 22)	θ value	5.76516e-39 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

SFRP4_HUMAN
NC score	0.879750 (rank : 23)	θ value	5.06226e-27 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP4_MOUSE
NC score	0.879442 (rank : 24)	θ value	5.06226e-27 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SFRP3_MOUSE
NC score	0.872220 (rank : 25)	θ value	2.42779e-29 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP3_HUMAN
NC score	0.871653 (rank : 26)	θ value	5.40856e-29 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP5_MOUSE
NC score	0.840417 (rank : 27)	θ value	2.20094e-22 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

SFRP5_HUMAN
NC score	0.840027 (rank : 28)	θ value	6.40375e-22 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP1_MOUSE
NC score	0.836423 (rank : 29)	θ value	6.62687e-19 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP2_MOUSE
NC score	0.836273 (rank : 30)	θ value	2.59989e-23 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP1_HUMAN
NC score	0.835980 (rank : 31)	θ value	8.65492e-19 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP2_HUMAN
NC score	0.835366 (rank : 32)	θ value	2.59989e-23 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

MFRP_MOUSE
NC score	0.445663 (rank : 33)	θ value	1.133e-10 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_HUMAN
NC score	0.440885 (rank : 34)	θ value	1.02475e-11 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPZ_HUMAN
NC score	0.427143 (rank : 35)	θ value	3.64472e-09 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
NC score	0.381836 (rank : 36)	θ value	1.53129e-07 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CORIN_MOUSE
NC score	0.289346 (rank : 37)	θ value	3.28887e-18 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	451	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CORIN_HUMAN
NC score	0.289132 (rank : 38)	θ value	7.32683e-18 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	453	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

COIA1_MOUSE
NC score	0.268024 (rank : 39)	θ value	5.26297e-08 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	481	Shared Neighborhood Hits	45
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GP157_HUMAN
NC score	0.178295 (rank : 40)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP157_MOUSE
NC score	0.167310 (rank : 41)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP155_HUMAN
NC score	0.111101 (rank : 42)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	89	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

GP133_HUMAN
NC score	0.064151 (rank : 43)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	115	Shared Neighborhood Hits	26
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP126_HUMAN
NC score	0.059144 (rank : 44)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	187	Shared Neighborhood Hits	26
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

TP53B_HUMAN
NC score	0.056513 (rank : 45)	θ value	0.0148317 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	413	Shared Neighborhood Hits	9
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TP53B_MOUSE
NC score	0.045056 (rank : 46)	θ value	0.0330416 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	644	Shared Neighborhood Hits	11
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

GPR64_MOUSE
NC score	0.043645 (rank : 47)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	156	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR64_HUMAN
NC score	0.043281 (rank : 48)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	207	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

LPHN3_HUMAN
NC score	0.041989 (rank : 49)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	139	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

SFT2A_HUMAN
NC score	0.036713 (rank : 50)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WV19, Q5TI64, Q9UIC7	Gene names	SFT2D1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) (pRGR1).

SFT2A_MOUSE
NC score	0.031696 (rank : 51)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SSN7	Gene names	Sft2d1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1).

CELR1_MOUSE
NC score	0.028755 (rank : 52)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	617	Shared Neighborhood Hits	27
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CF195_HUMAN
NC score	0.028466 (rank : 53)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MT4, Q5TAW4	Gene names	C6orf195
Domain Architecture	No domain graphic available
Description	Protein C6orf195.

TMM28_HUMAN
NC score	0.027744 (rank : 54)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O75949	Gene names	TMEM28, TED
Domain Architecture	No domain graphic available
Description	Transmembrane protein 28 (TED protein).

CELR3_MOUSE
NC score	0.023486 (rank : 55)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	687	Shared Neighborhood Hits	28
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR3_HUMAN
NC score	0.019292 (rank : 56)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	680	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

EDG3_HUMAN
NC score	0.017935 (rank : 57)	θ value	0.000270298 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	860	Shared Neighborhood Hits	8
SwissProt Accessions	Q99500, Q7Z5I2	Gene names	EDG3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3).

CELR1_HUMAN
NC score	0.017863 (rank : 58)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	613	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

SMBP2_HUMAN
NC score	0.014408 (rank : 59)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

RNF5_MOUSE
NC score	0.013522 (rank : 60)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RIN3_HUMAN
NC score	0.013303 (rank : 61)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SLIK1_MOUSE
NC score	0.012957 (rank : 62)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	333	Shared Neighborhood Hits	5
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

TRXR1_HUMAN
NC score	0.012496 (rank : 63)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q16881, Q76P53, Q7LA96, Q9UH79	Gene names	TXNRD1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic precursor (EC 1.8.1.9) (TR) (TR1).

SLIK1_HUMAN
NC score	0.012232 (rank : 64)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

EDG3_MOUSE
NC score	0.012173 (rank : 65)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	861	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0U9, Q8BP20	Gene names	Edg3, Lpb3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3).

DIDO1_HUMAN
NC score	0.009670 (rank : 66)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	960	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

CD2_HUMAN
NC score	0.009321 (rank : 67)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	504	Shared Neighborhood Hits	9
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

ZN385_HUMAN
NC score	0.009209 (rank : 68)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	614	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

RNF5_HUMAN
NC score	0.009016 (rank : 69)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

JIP2_HUMAN
NC score	0.008680 (rank : 70)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	288	Shared Neighborhood Hits	7
SwissProt Accessions	Q13387, Q96G62, Q99771, Q9NZ59, Q9UKQ4	Gene names	MAPK8IP2, IB2, JIP2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

RGS3_HUMAN
NC score	0.008455 (rank : 71)	θ value	0.0961366 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	1375	Shared Neighborhood Hits	14
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

K0310_HUMAN
NC score	0.007484 (rank : 72)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	420	Shared Neighborhood Hits	7
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

GP174_HUMAN
NC score	0.006180 (rank : 73)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	486	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXC1	Gene names	GPR174
Domain Architecture
Description	Probable G-protein coupled receptor 174.

GP174_MOUSE
NC score	0.005982 (rank : 74)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	480	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U507	Gene names	Gpr174, Gm376
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 174.

CI079_HUMAN
NC score	0.005874 (rank : 75)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	288	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

LCP2_HUMAN
NC score	0.005512 (rank : 76)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	531	Shared Neighborhood Hits	7
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

TR19L_HUMAN
NC score	0.005159 (rank : 77)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

RPGF1_HUMAN
NC score	0.005142 (rank : 78)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	262	Shared Neighborhood Hits	4
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

S23IP_MOUSE
NC score	0.004259 (rank : 79)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	363	Shared Neighborhood Hits	9
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

NACAM_MOUSE
NC score	0.003898 (rank : 80)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	1866	Shared Neighborhood Hits	21
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NMD3A_HUMAN
NC score	0.003024 (rank : 81)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

NCOR2_MOUSE
NC score	0.002819 (rank : 82)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	790	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

SC6A4_HUMAN
NC score	0.002628 (rank : 83)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P31645	Gene names	SLC6A4, HTT, SERT
Domain Architecture
Description	Sodium-dependent serotonin transporter (5HT transporter) (5HTT).

SC6A4_MOUSE
NC score	0.002394 (rank : 84)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	53	Shared Neighborhood Hits	3
SwissProt Accessions	Q60857, O35241	Gene names	Slc6a4, Htt, Sert
Domain Architecture
Description	Sodium-dependent serotonin transporter (5HT transporter) (5HTT).

SOX13_HUMAN
NC score	0.002044 (rank : 85)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	464	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

NOTC3_HUMAN
NC score	0.001997 (rank : 86)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	1062	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LIMD1_MOUSE
NC score	0.001892 (rank : 87)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXD8, Q8C8G4, Q9CW55	Gene names	Limd1
Domain Architecture
Description	LIM domain-containing protein 1.

SEM6C_MOUSE
NC score	0.001404 (rank : 88)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	352	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

ADA19_HUMAN
NC score	0.001284 (rank : 89)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	381	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

HXC11_HUMAN
NC score	-0.001268 (rank : 90)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	349	Shared Neighborhood Hits	4
SwissProt Accessions	O43248, Q96DH2	Gene names	HOXC11
Domain Architecture
Description	Homeobox protein Hox-C11.

ZFP28_HUMAN
NC score	-0.004989 (rank : 91)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	843	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).