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Network neighborhood for query Sequence : FZD4_MOUSE

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FZD4_MOUSE
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FZD4_HUMAN
θ value	0 (rank : 1)	NC score	0.999872 (rank : 2)
Query Neighborhood Hits	52	Target Neighborhood Hits	54	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

FZD4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	52
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

FZD10_HUMAN
θ value	8.88953e-157 (rank : 3)	NC score	0.993967 (rank : 3)
Query Neighborhood Hits	52	Target Neighborhood Hits	51	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD9_MOUSE
θ value	7.52544e-156 (rank : 4)	NC score	0.993090 (rank : 6)
Query Neighborhood Hits	52	Target Neighborhood Hits	66	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

FZD9_HUMAN
θ value	9.82853e-156 (rank : 5)	NC score	0.993309 (rank : 5)
Query Neighborhood Hits	52	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD10_MOUSE
θ value	4.87785e-155 (rank : 6)	NC score	0.993535 (rank : 4)
Query Neighborhood Hits	52	Target Neighborhood Hits	56	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

FZD1_HUMAN
θ value	1.38424e-125 (rank : 7)	NC score	0.985794 (rank : 14)
Query Neighborhood Hits	52	Target Neighborhood Hits	62	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD2_HUMAN
θ value	1.80787e-125 (rank : 8)	NC score	0.986173 (rank : 10)
Query Neighborhood Hits	52	Target Neighborhood Hits	57	Shared Neighborhood Hits	44
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD2_MOUSE
θ value	3.08376e-125 (rank : 9)	NC score	0.986090 (rank : 12)
Query Neighborhood Hits	52	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD5_HUMAN
θ value	1.43246e-122 (rank : 10)	NC score	0.987385 (rank : 7)
Query Neighborhood Hits	52	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD1_MOUSE
θ value	1.21265e-121 (rank : 11)	NC score	0.985126 (rank : 15)
Query Neighborhood Hits	52	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD7_HUMAN
θ value	1.21265e-121 (rank : 12)	NC score	0.986245 (rank : 9)
Query Neighborhood Hits	52	Target Neighborhood Hits	56	Shared Neighborhood Hits	44
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD5_MOUSE
θ value	2.06847e-121 (rank : 13)	NC score	0.987231 (rank : 8)
Query Neighborhood Hits	52	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD7_MOUSE
θ value	4.60808e-121 (rank : 14)	NC score	0.986026 (rank : 13)
Query Neighborhood Hits	52	Target Neighborhood Hits	59	Shared Neighborhood Hits	44
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD8_MOUSE
θ value	4.60808e-121 (rank : 15)	NC score	0.986119 (rank : 11)
Query Neighborhood Hits	52	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FZD8_HUMAN
θ value	1.18275e-92 (rank : 16)	NC score	0.983568 (rank : 16)
Query Neighborhood Hits	52	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD6_MOUSE
θ value	1.35324e-88 (rank : 17)	NC score	0.966770 (rank : 20)
Query Neighborhood Hits	52	Target Neighborhood Hits	135	Shared Neighborhood Hits	44
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

FZD3_HUMAN
θ value	1.49618e-87 (rank : 18)	NC score	0.967412 (rank : 19)
Query Neighborhood Hits	52	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD3_MOUSE
θ value	2.5521e-87 (rank : 19)	NC score	0.967479 (rank : 18)
Query Neighborhood Hits	52	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

FZD6_HUMAN
θ value	6.95003e-85 (rank : 20)	NC score	0.969221 (rank : 17)
Query Neighborhood Hits	52	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

SMO_HUMAN
θ value	6.58091e-43 (rank : 21)	NC score	0.893642 (rank : 21)
Query Neighborhood Hits	52	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

SMO_MOUSE
θ value	6.15952e-41 (rank : 22)	NC score	0.889153 (rank : 22)
Query Neighborhood Hits	52	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

CORIN_HUMAN
θ value	8.36355e-22 (rank : 23)	NC score	0.289673 (rank : 37)
Query Neighborhood Hits	52	Target Neighborhood Hits	453	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

SFRP1_MOUSE
θ value	1.09232e-21 (rank : 24)	NC score	0.830320 (rank : 27)
Query Neighborhood Hits	52	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP2_HUMAN
θ value	1.09232e-21 (rank : 25)	NC score	0.826814 (rank : 32)
Query Neighborhood Hits	52	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

SFRP2_MOUSE
θ value	1.09232e-21 (rank : 26)	NC score	0.827522 (rank : 31)
Query Neighborhood Hits	52	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP4_MOUSE
θ value	1.42661e-21 (rank : 27)	NC score	0.861007 (rank : 24)
Query Neighborhood Hits	52	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SFRP1_HUMAN
θ value	2.43343e-21 (rank : 28)	NC score	0.829465 (rank : 30)
Query Neighborhood Hits	52	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP4_HUMAN
θ value	3.17815e-21 (rank : 29)	NC score	0.861130 (rank : 23)
Query Neighborhood Hits	52	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP3_MOUSE
θ value	9.24701e-21 (rank : 30)	NC score	0.850412 (rank : 25)
Query Neighborhood Hits	52	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP3_HUMAN
θ value	1.2077e-20 (rank : 31)	NC score	0.849612 (rank : 26)
Query Neighborhood Hits	52	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

CORIN_MOUSE
θ value	2.69047e-20 (rank : 32)	NC score	0.289400 (rank : 38)
Query Neighborhood Hits	52	Target Neighborhood Hits	451	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

SFRP5_HUMAN
θ value	2.69047e-20 (rank : 33)	NC score	0.830063 (rank : 29)
Query Neighborhood Hits	52	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP5_MOUSE
θ value	7.82807e-20 (rank : 34)	NC score	0.830081 (rank : 28)
Query Neighborhood Hits	52	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

MFRP_MOUSE
θ value	1.58096e-12 (rank : 35)	NC score	0.445481 (rank : 33)
Query Neighborhood Hits	52	Target Neighborhood Hits	166	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_HUMAN
θ value	5.08577e-11 (rank : 36)	NC score	0.439608 (rank : 34)
Query Neighborhood Hits	52	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPZ_HUMAN
θ value	1.29631e-06 (rank : 37)	NC score	0.416634 (rank : 35)
Query Neighborhood Hits	52	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
θ value	3.19293e-05 (rank : 38)	NC score	0.371111 (rank : 36)
Query Neighborhood Hits	52	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

COIA1_MOUSE
θ value	0.000602161 (rank : 39)	NC score	0.255554 (rank : 39)
Query Neighborhood Hits	52	Target Neighborhood Hits	481	Shared Neighborhood Hits	37
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GP126_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.052240 (rank : 44)
Query Neighborhood Hits	52	Target Neighborhood Hits	187	Shared Neighborhood Hits	26
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP155_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.129235 (rank : 42)
Query Neighborhood Hits	52	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

LPHN3_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.035449 (rank : 45)
Query Neighborhood Hits	52	Target Neighborhood Hits	139	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

GLP1R_MOUSE
θ value	1.06291 (rank : 43)	NC score	0.012459 (rank : 49)
Query Neighborhood Hits	52	Target Neighborhood Hits	80	Shared Neighborhood Hits	10
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

GP133_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.060834 (rank : 43)
Query Neighborhood Hits	52	Target Neighborhood Hits	115	Shared Neighborhood Hits	25
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP157_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.161681 (rank : 40)
Query Neighborhood Hits	52	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

TRXR1_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.016254 (rank : 48)
Query Neighborhood Hits	52	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q16881, Q76P53, Q7LA96, Q9UH79	Gene names	TXNRD1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic precursor (EC 1.8.1.9) (TR) (TR1).

TRXR1_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.012128 (rank : 50)
Query Neighborhood Hits	52	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JMH6	Gene names	Txnrd1, Trxr1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic (EC 1.8.1.9) (TR) (TR1).

EMR1_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.007962 (rank : 52)
Query Neighborhood Hits	52	Target Neighborhood Hits	382	Shared Neighborhood Hits	14
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EDG6_MOUSE
θ value	6.88961 (rank : 49)	NC score	0.003952 (rank : 53)
Query Neighborhood Hits	52	Target Neighborhood Hits	462	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0L1, Q3U4H3, Q8C6E2, Q8K1R9	Gene names	Edg6, Lpc1, S1p4
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-6 (S1P receptor Edg-6) (Endothelial differentiation G-protein coupled receptor 6) (Lysophospholipid receptor C1) (Sphingosine 1-phosphate receptor 4) (S1P4).

GLP1R_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.008866 (rank : 51)
Query Neighborhood Hits	52	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	P43220, Q99669	Gene names	GLP1R
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

GP112_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.031327 (rank : 47)
Query Neighborhood Hits	52	Target Neighborhood Hits	441	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GPR64_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.032782 (rank : 46)
Query Neighborhood Hits	52	Target Neighborhood Hits	207	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GP157_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.148839 (rank : 41)
Query Neighborhood Hits	52	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

Hits sorted by NC score

FZD4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	52	Target Neighborhood Hits	52	Shared Neighborhood Hits	52
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

FZD4_HUMAN
NC score	0.999872 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	52	Target Neighborhood Hits	54	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

FZD10_HUMAN
NC score	0.993967 (rank : 3)	θ value	8.88953e-157 (rank : 3)
Query Neighborhood Hits	52	Target Neighborhood Hits	51	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD10_MOUSE
NC score	0.993535 (rank : 4)	θ value	4.87785e-155 (rank : 6)
Query Neighborhood Hits	52	Target Neighborhood Hits	56	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

FZD9_HUMAN
NC score	0.993309 (rank : 5)	θ value	9.82853e-156 (rank : 5)
Query Neighborhood Hits	52	Target Neighborhood Hits	63	Shared Neighborhood Hits	44
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD9_MOUSE
NC score	0.993090 (rank : 6)	θ value	7.52544e-156 (rank : 4)
Query Neighborhood Hits	52	Target Neighborhood Hits	66	Shared Neighborhood Hits	45
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

FZD5_HUMAN
NC score	0.987385 (rank : 7)	θ value	1.43246e-122 (rank : 10)
Query Neighborhood Hits	52	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD5_MOUSE
NC score	0.987231 (rank : 8)	θ value	2.06847e-121 (rank : 13)
Query Neighborhood Hits	52	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD7_HUMAN
NC score	0.986245 (rank : 9)	θ value	1.21265e-121 (rank : 12)
Query Neighborhood Hits	52	Target Neighborhood Hits	56	Shared Neighborhood Hits	44
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD2_HUMAN
NC score	0.986173 (rank : 10)	θ value	1.80787e-125 (rank : 8)
Query Neighborhood Hits	52	Target Neighborhood Hits	57	Shared Neighborhood Hits	44
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD8_MOUSE
NC score	0.986119 (rank : 11)	θ value	4.60808e-121 (rank : 15)
Query Neighborhood Hits	52	Target Neighborhood Hits	89	Shared Neighborhood Hits	44
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FZD2_MOUSE
NC score	0.986090 (rank : 12)	θ value	3.08376e-125 (rank : 9)
Query Neighborhood Hits	52	Target Neighborhood Hits	60	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD7_MOUSE
NC score	0.986026 (rank : 13)	θ value	4.60808e-121 (rank : 14)
Query Neighborhood Hits	52	Target Neighborhood Hits	59	Shared Neighborhood Hits	44
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD1_HUMAN
NC score	0.985794 (rank : 14)	θ value	1.38424e-125 (rank : 7)
Query Neighborhood Hits	52	Target Neighborhood Hits	62	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD1_MOUSE
NC score	0.985126 (rank : 15)	θ value	1.21265e-121 (rank : 11)
Query Neighborhood Hits	52	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD8_HUMAN
NC score	0.983568 (rank : 16)	θ value	1.18275e-92 (rank : 16)
Query Neighborhood Hits	52	Target Neighborhood Hits	88	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD6_HUMAN
NC score	0.969221 (rank : 17)	θ value	6.95003e-85 (rank : 20)
Query Neighborhood Hits	52	Target Neighborhood Hits	84	Shared Neighborhood Hits	43
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

FZD3_MOUSE
NC score	0.967479 (rank : 18)	θ value	2.5521e-87 (rank : 19)
Query Neighborhood Hits	52	Target Neighborhood Hits	75	Shared Neighborhood Hits	44
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

FZD3_HUMAN
NC score	0.967412 (rank : 19)	θ value	1.49618e-87 (rank : 18)
Query Neighborhood Hits	52	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD6_MOUSE
NC score	0.966770 (rank : 20)	θ value	1.35324e-88 (rank : 17)
Query Neighborhood Hits	52	Target Neighborhood Hits	135	Shared Neighborhood Hits	44
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

SMO_HUMAN
NC score	0.893642 (rank : 21)	θ value	6.58091e-43 (rank : 21)
Query Neighborhood Hits	52	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

SMO_MOUSE
NC score	0.889153 (rank : 22)	θ value	6.15952e-41 (rank : 22)
Query Neighborhood Hits	52	Target Neighborhood Hits	61	Shared Neighborhood Hits	37
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

SFRP4_HUMAN
NC score	0.861130 (rank : 23)	θ value	3.17815e-21 (rank : 29)
Query Neighborhood Hits	52	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP4_MOUSE
NC score	0.861007 (rank : 24)	θ value	1.42661e-21 (rank : 27)
Query Neighborhood Hits	52	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SFRP3_MOUSE
NC score	0.850412 (rank : 25)	θ value	9.24701e-21 (rank : 30)
Query Neighborhood Hits	52	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP3_HUMAN
NC score	0.849612 (rank : 26)	θ value	1.2077e-20 (rank : 31)
Query Neighborhood Hits	52	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP1_MOUSE
NC score	0.830320 (rank : 27)	θ value	1.09232e-21 (rank : 24)
Query Neighborhood Hits	52	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP5_MOUSE
NC score	0.830081 (rank : 28)	θ value	7.82807e-20 (rank : 34)
Query Neighborhood Hits	52	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

SFRP5_HUMAN
NC score	0.830063 (rank : 29)	θ value	2.69047e-20 (rank : 33)
Query Neighborhood Hits	52	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP1_HUMAN
NC score	0.829465 (rank : 30)	θ value	2.43343e-21 (rank : 28)
Query Neighborhood Hits	52	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP2_MOUSE
NC score	0.827522 (rank : 31)	θ value	1.09232e-21 (rank : 26)
Query Neighborhood Hits	52	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP2_HUMAN
NC score	0.826814 (rank : 32)	θ value	1.09232e-21 (rank : 25)
Query Neighborhood Hits	52	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

MFRP_MOUSE
NC score	0.445481 (rank : 33)	θ value	1.58096e-12 (rank : 35)
Query Neighborhood Hits	52	Target Neighborhood Hits	166	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_HUMAN
NC score	0.439608 (rank : 34)	θ value	5.08577e-11 (rank : 36)
Query Neighborhood Hits	52	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPZ_HUMAN
NC score	0.416634 (rank : 35)	θ value	1.29631e-06 (rank : 37)
Query Neighborhood Hits	52	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
NC score	0.371111 (rank : 36)	θ value	3.19293e-05 (rank : 38)
Query Neighborhood Hits	52	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CORIN_HUMAN
NC score	0.289673 (rank : 37)	θ value	8.36355e-22 (rank : 23)
Query Neighborhood Hits	52	Target Neighborhood Hits	453	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
NC score	0.289400 (rank : 38)	θ value	2.69047e-20 (rank : 32)
Query Neighborhood Hits	52	Target Neighborhood Hits	451	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

COIA1_MOUSE
NC score	0.255554 (rank : 39)	θ value	0.000602161 (rank : 39)
Query Neighborhood Hits	52	Target Neighborhood Hits	481	Shared Neighborhood Hits	37
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GP157_HUMAN
NC score	0.161681 (rank : 40)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	52	Target Neighborhood Hits	93	Shared Neighborhood Hits	28
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP157_MOUSE
NC score	0.148839 (rank : 41)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	52	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP155_HUMAN
NC score	0.129235 (rank : 42)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	52	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

GP133_HUMAN
NC score	0.060834 (rank : 43)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	52	Target Neighborhood Hits	115	Shared Neighborhood Hits	25
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP126_HUMAN
NC score	0.052240 (rank : 44)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	52	Target Neighborhood Hits	187	Shared Neighborhood Hits	26
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

LPHN3_HUMAN
NC score	0.035449 (rank : 45)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	52	Target Neighborhood Hits	139	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

GPR64_HUMAN
NC score	0.032782 (rank : 46)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	52	Target Neighborhood Hits	207	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GP112_HUMAN
NC score	0.031327 (rank : 47)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	52	Target Neighborhood Hits	441	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

TRXR1_HUMAN
NC score	0.016254 (rank : 48)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	52	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q16881, Q76P53, Q7LA96, Q9UH79	Gene names	TXNRD1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic precursor (EC 1.8.1.9) (TR) (TR1).

GLP1R_MOUSE
NC score	0.012459 (rank : 49)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	52	Target Neighborhood Hits	80	Shared Neighborhood Hits	10
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

TRXR1_MOUSE
NC score	0.012128 (rank : 50)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	52	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JMH6	Gene names	Txnrd1, Trxr1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic (EC 1.8.1.9) (TR) (TR1).

GLP1R_HUMAN
NC score	0.008866 (rank : 51)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	52	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	P43220, Q99669	Gene names	GLP1R
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

EMR1_HUMAN
NC score	0.007962 (rank : 52)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	52	Target Neighborhood Hits	382	Shared Neighborhood Hits	14
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EDG6_MOUSE
NC score	0.003952 (rank : 53)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	52	Target Neighborhood Hits	462	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0L1, Q3U4H3, Q8C6E2, Q8K1R9	Gene names	Edg6, Lpc1, S1p4
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-6 (S1P receptor Edg-6) (Endothelial differentiation G-protein coupled receptor 6) (Lysophospholipid receptor C1) (Sphingosine 1-phosphate receptor 4) (S1P4).