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Network neighborhood for query Sequence : FZD8_HUMAN

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FZD8_HUMAN
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FZD8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD8_MOUSE
θ value	0 (rank : 2)	NC score	0.998000 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	89	Shared Neighborhood Hits	65
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FZD5_HUMAN
θ value	3.16172e-154 (rank : 3)	NC score	0.992418 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	71	Shared Neighborhood Hits	51
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD5_MOUSE
θ value	3.49569e-153 (rank : 4)	NC score	0.992566 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD7_MOUSE
θ value	2.35023e-141 (rank : 5)	NC score	0.986368 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	46
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD7_HUMAN
θ value	3.06949e-141 (rank : 6)	NC score	0.986409 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD10_MOUSE
θ value	6.43005e-123 (rank : 7)	NC score	0.985949 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	56	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

FZD10_HUMAN
θ value	7.86017e-121 (rank : 8)	NC score	0.986282 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD9_MOUSE
θ value	1.34698e-104 (rank : 9)	NC score	0.984276 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	66	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

FZD2_HUMAN
θ value	2.2976e-104 (rank : 10)	NC score	0.983326 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD2_MOUSE
θ value	2.2976e-104 (rank : 11)	NC score	0.983212 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD9_HUMAN
θ value	1.94503e-103 (rank : 12)	NC score	0.984183 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	63	Shared Neighborhood Hits	46
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD1_HUMAN
θ value	1.82049e-101 (rank : 13)	NC score	0.982271 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	62	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD1_MOUSE
θ value	6.47494e-99 (rank : 14)	NC score	0.981732 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	63	Shared Neighborhood Hits	48
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD4_HUMAN
θ value	6.93392e-93 (rank : 15)	NC score	0.983720 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	54	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

FZD4_MOUSE
θ value	1.18275e-92 (rank : 16)	NC score	0.983568 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

FZD3_HUMAN
θ value	2.56397e-71 (rank : 17)	NC score	0.960615 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD3_MOUSE
θ value	4.37348e-71 (rank : 18)	NC score	0.960751 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	75	Shared Neighborhood Hits	45
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

FZD6_HUMAN
θ value	2.17053e-70 (rank : 19)	NC score	0.962458 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	84	Shared Neighborhood Hits	47
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

FZD6_MOUSE
θ value	3.13423e-69 (rank : 20)	NC score	0.958918 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	135	Shared Neighborhood Hits	47
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

SMO_HUMAN
θ value	7.52953e-39 (rank : 21)	NC score	0.884413 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

SMO_MOUSE
θ value	2.19075e-38 (rank : 22)	NC score	0.880087 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

SFRP3_HUMAN
θ value	5.40856e-29 (rank : 23)	NC score	0.873032 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP3_MOUSE
θ value	5.40856e-29 (rank : 24)	NC score	0.873572 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP4_HUMAN
θ value	5.06226e-27 (rank : 25)	NC score	0.881083 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP4_MOUSE
θ value	5.06226e-27 (rank : 26)	NC score	0.880722 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SFRP2_HUMAN
θ value	2.59989e-23 (rank : 27)	NC score	0.836464 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

SFRP2_MOUSE
θ value	2.59989e-23 (rank : 28)	NC score	0.837394 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP5_MOUSE
θ value	2.20094e-22 (rank : 29)	NC score	0.841833 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

SFRP5_HUMAN
θ value	6.40375e-22 (rank : 30)	NC score	0.841326 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP1_MOUSE
θ value	5.07402e-19 (rank : 31)	NC score	0.837445 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP1_HUMAN
θ value	6.62687e-19 (rank : 32)	NC score	0.837038 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

CORIN_MOUSE
θ value	3.28887e-18 (rank : 33)	NC score	0.289793 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	451	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CORIN_HUMAN
θ value	7.32683e-18 (rank : 34)	NC score	0.289451 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	453	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

MFRP_HUMAN
θ value	1.02475e-11 (rank : 35)	NC score	0.441601 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	1.133e-10 (rank : 36)	NC score	0.446125 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	166	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPZ_HUMAN
θ value	3.64472e-09 (rank : 37)	NC score	0.428271 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

COIA1_MOUSE
θ value	5.26297e-08 (rank : 38)	NC score	0.270058 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	481	Shared Neighborhood Hits	45
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CBPZ_MOUSE
θ value	1.53129e-07 (rank : 39)	NC score	0.382880 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

EDG3_HUMAN
θ value	0.000270298 (rank : 40)	NC score	0.018205 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	860	Shared Neighborhood Hits	8
SwissProt Accessions	Q99500, Q7Z5I2	Gene names	EDG3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3).

TP53B_HUMAN
θ value	0.00228821 (rank : 41)	NC score	0.064171 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	413	Shared Neighborhood Hits	9
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

TP53B_MOUSE
θ value	0.00509761 (rank : 42)	NC score	0.050528 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	644	Shared Neighborhood Hits	7
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SLIK1_HUMAN
θ value	0.0431538 (rank : 43)	NC score	0.014029 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

CELR1_MOUSE
θ value	0.0961366 (rank : 44)	NC score	0.028687 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	617	Shared Neighborhood Hits	28
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

EDG3_MOUSE
θ value	0.125558 (rank : 45)	NC score	0.012375 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	861	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0U9, Q8BP20	Gene names	Edg3, Lpb3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3).

SLIK1_MOUSE
θ value	0.125558 (rank : 46)	NC score	0.014701 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	333	Shared Neighborhood Hits	5
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

CELR3_MOUSE
θ value	0.21417 (rank : 47)	NC score	0.023458 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	687	Shared Neighborhood Hits	28
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

GP126_HUMAN
θ value	0.21417 (rank : 48)	NC score	0.058946 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	187	Shared Neighborhood Hits	26
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP157_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.178615 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

LPHN3_HUMAN
θ value	0.365318 (rank : 50)	NC score	0.041717 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	139	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

GP157_MOUSE
θ value	0.62314 (rank : 51)	NC score	0.168265 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GPR64_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.043293 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	207	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

RP1L1_HUMAN
θ value	0.813845 (rank : 53)	NC score	0.013283 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	1072	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

CELR1_HUMAN
θ value	1.06291 (rank : 54)	NC score	0.017780 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	613	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR3_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.019295 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	680	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CEL_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.004473 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	896	Shared Neighborhood Hits	11
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

GP174_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.006401 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	486	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BXC1	Gene names	GPR174
Domain Architecture
Description	Probable G-protein coupled receptor 174.

SFT2A_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.037096 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WV19, Q5TI64, Q9UIC7	Gene names	SFT2D1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) (pRGR1).

GP174_MOUSE
θ value	1.81305 (rank : 59)	NC score	0.006195 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	480	Shared Neighborhood Hits	9
SwissProt Accessions	Q3U507	Gene names	Gpr174, Gm376
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 174.

IP3KA_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.009375 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

JPH2_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.005539 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	639	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

SFT2A_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.032028 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SSN7	Gene names	Sft2d1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1).

TBX21_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.003840 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TMM28_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.027514 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	O75949	Gene names	TMEM28, TED
Domain Architecture	No domain graphic available
Description	Transmembrane protein 28 (TED protein).

INP5E_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.007301 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	201	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

TENX_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.005736 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	789	Shared Neighborhood Hits	13
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

DOK7_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.008898 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

CD2_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.008679 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	504	Shared Neighborhood Hits	6
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CI040_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.012146 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCE4, Q8BJJ5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf40 homolog.

GPR64_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.043529 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

KINH_HUMAN
θ value	5.27518 (rank : 71)	NC score	-0.002588 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	1231	Shared Neighborhood Hits	5
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

KINH_MOUSE
θ value	5.27518 (rank : 72)	NC score	-0.001876 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	1082	Shared Neighborhood Hits	5
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

LTBP2_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.004546 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	617	Shared Neighborhood Hits	9
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NMD3A_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.003625 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

SET1A_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.003871 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	690	Shared Neighborhood Hits	12
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TCGAP_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.000690 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	872	Shared Neighborhood Hits	10
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TRXR1_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.012178 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q16881, Q76P53, Q7LA96, Q9UH79	Gene names	TXNRD1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic precursor (EC 1.8.1.9) (TR) (TR1).

CNTRB_HUMAN
θ value	6.88961 (rank : 78)	NC score	-0.000630 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	690	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

COG8_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.006155 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

MUC1_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.002607 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CO7A1_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.003876 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	807	Shared Neighborhood Hits	9
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO9A3_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.006050 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	361	Shared Neighborhood Hits	9
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

GPR61_HUMAN
θ value	8.99809 (rank : 83)	NC score	-0.002683 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	710	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZJ8, Q6NWS0, Q8TDV4, Q96PR4	Gene names	GPR61, BALGR
Domain Architecture
Description	Probable G-protein coupled receptor 61 (Biogenic amine receptor-like G-protein coupled receptor).

HME2_MOUSE
θ value	8.99809 (rank : 84)	NC score	-0.001884 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	352	Shared Neighborhood Hits	3
SwissProt Accessions	P09066	Gene names	En2, En-2
Domain Architecture
Description	Homeobox protein engrailed-2 (Mo-En-2).

IF4B_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.002343 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	368	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

RNF5_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.008050 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

SC6A4_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.001117 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P31645	Gene names	SLC6A4, HTT, SERT
Domain Architecture
Description	Sodium-dependent serotonin transporter (5HT transporter) (5HTT).

ZN467_MOUSE
θ value	8.99809 (rank : 88)	NC score	-0.005441 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	794	Shared Neighborhood Hits	3
SwissProt Accessions	Q8JZL0, Q9JJ98	Gene names	Znf467, Ezi, Zfp467
Domain Architecture	No domain graphic available
Description	Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI).

GP133_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.063979 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	115	Shared Neighborhood Hits	26
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP155_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.110219 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

Hits sorted by NC score

FZD8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD8_MOUSE
NC score	0.998000 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	89	Shared Neighborhood Hits	65
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FZD5_MOUSE
NC score	0.992566 (rank : 3)	θ value	3.49569e-153 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD5_HUMAN
NC score	0.992418 (rank : 4)	θ value	3.16172e-154 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	71	Shared Neighborhood Hits	51
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD7_HUMAN
NC score	0.986409 (rank : 5)	θ value	3.06949e-141 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	56	Shared Neighborhood Hits	46
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD7_MOUSE
NC score	0.986368 (rank : 6)	θ value	2.35023e-141 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	59	Shared Neighborhood Hits	46
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD10_HUMAN
NC score	0.986282 (rank : 7)	θ value	7.86017e-121 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD10_MOUSE
NC score	0.985949 (rank : 8)	θ value	6.43005e-123 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	56	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

FZD9_MOUSE
NC score	0.984276 (rank : 9)	θ value	1.34698e-104 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	66	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

FZD9_HUMAN
NC score	0.984183 (rank : 10)	θ value	1.94503e-103 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	63	Shared Neighborhood Hits	46
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD4_HUMAN
NC score	0.983720 (rank : 11)	θ value	6.93392e-93 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	54	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

FZD4_MOUSE
NC score	0.983568 (rank : 12)	θ value	1.18275e-92 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

FZD2_HUMAN
NC score	0.983326 (rank : 13)	θ value	2.2976e-104 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	57	Shared Neighborhood Hits	47
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD2_MOUSE
NC score	0.983212 (rank : 14)	θ value	2.2976e-104 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD1_HUMAN
NC score	0.982271 (rank : 15)	θ value	1.82049e-101 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	62	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD1_MOUSE
NC score	0.981732 (rank : 16)	θ value	6.47494e-99 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	63	Shared Neighborhood Hits	48
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD6_HUMAN
NC score	0.962458 (rank : 17)	θ value	2.17053e-70 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	84	Shared Neighborhood Hits	47
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

FZD3_MOUSE
NC score	0.960751 (rank : 18)	θ value	4.37348e-71 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	75	Shared Neighborhood Hits	45
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

FZD3_HUMAN
NC score	0.960615 (rank : 19)	θ value	2.56397e-71 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD6_MOUSE
NC score	0.958918 (rank : 20)	θ value	3.13423e-69 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	135	Shared Neighborhood Hits	47
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

SMO_HUMAN
NC score	0.884413 (rank : 21)	θ value	7.52953e-39 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

SFRP4_HUMAN
NC score	0.881083 (rank : 22)	θ value	5.06226e-27 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP4_MOUSE
NC score	0.880722 (rank : 23)	θ value	5.06226e-27 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SMO_MOUSE
NC score	0.880087 (rank : 24)	θ value	2.19075e-38 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

SFRP3_MOUSE
NC score	0.873572 (rank : 25)	θ value	5.40856e-29 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP3_HUMAN
NC score	0.873032 (rank : 26)	θ value	5.40856e-29 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP5_MOUSE
NC score	0.841833 (rank : 27)	θ value	2.20094e-22 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

SFRP5_HUMAN
NC score	0.841326 (rank : 28)	θ value	6.40375e-22 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP1_MOUSE
NC score	0.837445 (rank : 29)	θ value	5.07402e-19 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP2_MOUSE
NC score	0.837394 (rank : 30)	θ value	2.59989e-23 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP1_HUMAN
NC score	0.837038 (rank : 31)	θ value	6.62687e-19 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP2_HUMAN
NC score	0.836464 (rank : 32)	θ value	2.59989e-23 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

MFRP_MOUSE
NC score	0.446125 (rank : 33)	θ value	1.133e-10 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	166	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_HUMAN
NC score	0.441601 (rank : 34)	θ value	1.02475e-11 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	165	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPZ_HUMAN
NC score	0.428271 (rank : 35)	θ value	3.64472e-09 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
NC score	0.382880 (rank : 36)	θ value	1.53129e-07 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CORIN_MOUSE
NC score	0.289793 (rank : 37)	θ value	3.28887e-18 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	451	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CORIN_HUMAN
NC score	0.289451 (rank : 38)	θ value	7.32683e-18 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	453	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

COIA1_MOUSE
NC score	0.270058 (rank : 39)	θ value	5.26297e-08 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	481	Shared Neighborhood Hits	45
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GP157_HUMAN
NC score	0.178615 (rank : 40)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	31
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP157_MOUSE
NC score	0.168265 (rank : 41)	θ value	0.62314 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP155_HUMAN
NC score	0.110219 (rank : 42)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

TP53B_HUMAN
NC score	0.064171 (rank : 43)	θ value	0.00228821 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	413	Shared Neighborhood Hits	9
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

GP133_HUMAN
NC score	0.063979 (rank : 44)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	115	Shared Neighborhood Hits	26
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP126_HUMAN
NC score	0.058946 (rank : 45)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	187	Shared Neighborhood Hits	26
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

TP53B_MOUSE
NC score	0.050528 (rank : 46)	θ value	0.00509761 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	644	Shared Neighborhood Hits	7
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

GPR64_MOUSE
NC score	0.043529 (rank : 47)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR64_HUMAN
NC score	0.043293 (rank : 48)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	207	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

LPHN3_HUMAN
NC score	0.041717 (rank : 49)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	139	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

SFT2A_HUMAN
NC score	0.037096 (rank : 50)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WV19, Q5TI64, Q9UIC7	Gene names	SFT2D1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) (pRGR1).

SFT2A_MOUSE
NC score	0.032028 (rank : 51)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SSN7	Gene names	Sft2d1
Domain Architecture	No domain graphic available
Description	Vesicle transport protein SFT2A (SFT2 domain-containing protein 1).

CELR1_MOUSE
NC score	0.028687 (rank : 52)	θ value	0.0961366 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	617	Shared Neighborhood Hits	28
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

TMM28_HUMAN
NC score	0.027514 (rank : 53)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	O75949	Gene names	TMEM28, TED
Domain Architecture	No domain graphic available
Description	Transmembrane protein 28 (TED protein).

CELR3_MOUSE
NC score	0.023458 (rank : 54)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	687	Shared Neighborhood Hits	28
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR3_HUMAN
NC score	0.019295 (rank : 55)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	680	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

EDG3_HUMAN
NC score	0.018205 (rank : 56)	θ value	0.000270298 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	860	Shared Neighborhood Hits	8
SwissProt Accessions	Q99500, Q7Z5I2	Gene names	EDG3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3).

CELR1_HUMAN
NC score	0.017780 (rank : 57)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	613	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

SLIK1_MOUSE
NC score	0.014701 (rank : 58)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	333	Shared Neighborhood Hits	5
SwissProt Accessions	Q810C1, Q9CXL0	Gene names	Slitrk1, Sltk1
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor.

SLIK1_HUMAN
NC score	0.014029 (rank : 59)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	297	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PX8, Q5U5I6, Q96SF9	Gene names	SLITRK1, KIAA1910, LRRC12
Domain Architecture
Description	SLIT and NTRK-like protein 1 precursor (Leucine-rich repeat-containing protein 12).

RP1L1_HUMAN
NC score	0.013283 (rank : 60)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	1072	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

EDG3_MOUSE
NC score	0.012375 (rank : 61)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	861	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0U9, Q8BP20	Gene names	Edg3, Lpb3
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3).

TRXR1_HUMAN
NC score	0.012178 (rank : 62)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	Q16881, Q76P53, Q7LA96, Q9UH79	Gene names	TXNRD1
Domain Architecture
Description	Thioredoxin reductase 1, cytoplasmic precursor (EC 1.8.1.9) (TR) (TR1).

CI040_MOUSE
NC score	0.012146 (rank : 63)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCE4, Q8BJJ5	Gene names
Domain Architecture	No domain graphic available
Description	Protein C9orf40 homolog.

IP3KA_HUMAN
NC score	0.009375 (rank : 64)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

DOK7_MOUSE
NC score	0.008898 (rank : 65)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

CD2_HUMAN
NC score	0.008679 (rank : 66)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	504	Shared Neighborhood Hits	6
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

RNF5_MOUSE
NC score	0.008050 (rank : 67)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

INP5E_HUMAN
NC score	0.007301 (rank : 68)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	201	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

GP174_HUMAN
NC score	0.006401 (rank : 69)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	486	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BXC1	Gene names	GPR174
Domain Architecture
Description	Probable G-protein coupled receptor 174.

GP174_MOUSE
NC score	0.006195 (rank : 70)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	480	Shared Neighborhood Hits	9
SwissProt Accessions	Q3U507	Gene names	Gpr174, Gm376
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 174.

COG8_MOUSE
NC score	0.006155 (rank : 71)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	147	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

CO9A3_HUMAN
NC score	0.006050 (rank : 72)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	361	Shared Neighborhood Hits	9
SwissProt Accessions	Q14050, Q13681, Q9H4G9, Q9UPE2	Gene names	COL9A3
Domain Architecture	No domain graphic available
Description	Collagen alpha-3(IX) chain precursor.

TENX_HUMAN
NC score	0.005736 (rank : 73)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	789	Shared Neighborhood Hits	13
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

JPH2_HUMAN
NC score	0.005539 (rank : 74)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	639	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

LTBP2_MOUSE
NC score	0.004546 (rank : 75)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	617	Shared Neighborhood Hits	9
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CEL_HUMAN
NC score	0.004473 (rank : 76)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	896	Shared Neighborhood Hits	11
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CO7A1_HUMAN
NC score	0.003876 (rank : 77)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	807	Shared Neighborhood Hits	9
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

SET1A_HUMAN
NC score	0.003871 (rank : 78)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	690	Shared Neighborhood Hits	12
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TBX21_HUMAN
NC score	0.003840 (rank : 79)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UL17	Gene names	TBX21, TBET, TBLYM
Domain Architecture
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

NMD3A_HUMAN
NC score	0.003625 (rank : 80)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TCU5, Q8TF29, Q8WXI6	Gene names	GRIN3A, KIAA1973
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3A precursor (N-methyl-D-aspartate receptor subtype NR3A) (NMDAR-L).

MUC1_HUMAN
NC score	0.002607 (rank : 81)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

IF4B_MOUSE
NC score	0.002343 (rank : 82)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	368	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

SC6A4_HUMAN
NC score	0.001117 (rank : 83)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P31645	Gene names	SLC6A4, HTT, SERT
Domain Architecture
Description	Sodium-dependent serotonin transporter (5HT transporter) (5HTT).

TCGAP_HUMAN
NC score	0.000690 (rank : 84)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	872	Shared Neighborhood Hits	10
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CNTRB_HUMAN
NC score	-0.000630 (rank : 85)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	690	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

KINH_MOUSE
NC score	-0.001876 (rank : 86)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	1082	Shared Neighborhood Hits	5
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

HME2_MOUSE
NC score	-0.001884 (rank : 87)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	352	Shared Neighborhood Hits	3
SwissProt Accessions	P09066	Gene names	En2, En-2
Domain Architecture
Description	Homeobox protein engrailed-2 (Mo-En-2).

KINH_HUMAN
NC score	-0.002588 (rank : 88)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	1231	Shared Neighborhood Hits	5
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

GPR61_HUMAN
NC score	-0.002683 (rank : 89)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	710	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZJ8, Q6NWS0, Q8TDV4, Q96PR4	Gene names	GPR61, BALGR
Domain Architecture
Description	Probable G-protein coupled receptor 61 (Biogenic amine receptor-like G-protein coupled receptor).

ZN467_MOUSE
NC score	-0.005441 (rank : 90)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	794	Shared Neighborhood Hits	3
SwissProt Accessions	Q8JZL0, Q9JJ98	Gene names	Znf467, Ezi, Zfp467
Domain Architecture	No domain graphic available
Description	Zinc finger protein 467 (Endothelial cell-derived zinc finger protein) (EZI).