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Network neighborhood for query Sequence : IP3KA_HUMAN

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IP3KA_HUMAN
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IP3KA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

IP3KA_MOUSE
θ value	0 (rank : 2)	NC score	0.990844 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R071	Gene names	Itpka
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

IP3KB_HUMAN
θ value	4.77967e-110 (rank : 3)	NC score	0.938154 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	124	Shared Neighborhood Hits	11
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

IP3KC_MOUSE
θ value	4.6295e-105 (rank : 4)	NC score	0.950589 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

IP3KC_HUMAN
θ value	3.00075e-104 (rank : 5)	NC score	0.951304 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

IPMK_MOUSE
θ value	0.0193708 (rank : 6)	NC score	0.180411 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TT16, Q8BZ11, Q8BZA8, Q9CWM9	Gene names	Ipmk, Impk
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

OBSCN_HUMAN
θ value	0.0736092 (rank : 7)	NC score	0.009838 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	1931	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

IPMK_HUMAN
θ value	0.0961366 (rank : 8)	NC score	0.180590 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NFU5	Gene names	IPMK, IMPK
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

AAK1_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.012385 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	1077	Shared Neighborhood Hits	10
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

IP6K3_HUMAN
θ value	0.163984 (rank : 10)	NC score	0.120703 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q96PC2, Q96MQ9	Gene names	IHPK3, IP6K3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

WNK2_HUMAN
θ value	0.62314 (rank : 11)	NC score	0.007802 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	1407	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

YLPM1_MOUSE
θ value	0.62314 (rank : 12)	NC score	0.028693 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	505	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

IP6K3_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.110142 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BWD2	Gene names	Ihpk3, Ip6k3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

PELP1_MOUSE
θ value	0.813845 (rank : 14)	NC score	0.035603 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	709	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

PRELP_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.013961 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

BRD4_MOUSE
θ value	1.06291 (rank : 16)	NC score	0.016209 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	845	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

RBM12_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.036689 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	298	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM12_MOUSE
θ value	1.06291 (rank : 18)	NC score	0.035126 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

CJ078_MOUSE
θ value	1.38821 (rank : 19)	NC score	0.024576 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	559	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

PRELP_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.013486 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JK53	Gene names	Prelp
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

TRHY_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.009081 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	1385	Shared Neighborhood Hits	11
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

FZD8_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.009375 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

LRC34_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.022788 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

WASL_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.019753 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	339	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

E41L5_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.011643 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

IP6K2_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.094266 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UHH9, Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6	Gene names	IHPK2, IP6K2
Domain Architecture	No domain graphic available
Description	Inositol hexakisphosphate kinase 2 (EC 2.7.4.21) (InsP6 kinase 2) (Inositol hexakisphosphate kinase 2) (P(i)-uptake stimulator) (PiUS).

SFR15_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.023836 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

ERAL_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.021737 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	O75616, O75617, Q8WUY4, Q96LE2, Q96TC0	Gene names	ERAL1, HERA
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (hERA) (ERA-W) (Conserved ERA-like GTPase) (CEGA).

FMN1A_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.021249 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	423	Shared Neighborhood Hits	9
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.020753 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	447	Shared Neighborhood Hits	10
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

FOG1_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.004877 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	981	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GGN_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.019798 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	311	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

IP6K2_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.093158 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q80V72	Gene names	Ihpk2, Ip6k2
Domain Architecture	No domain graphic available
Description	Inositol hexakisphosphate kinase 2 (EC 2.7.4.21) (InsP6 kinase 2) (Inositol hexakisphosphate kinase 2) (P(i)-uptake stimulator) (PiUS).

MCATL_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.016578 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N8R3	Gene names	SLC25A29, C14orf69
Domain Architecture
Description	Mitochondrial carnitine/acylcarnitine carrier protein CACL (CACT-like) (Solute carrier family 25 member 29).

MTF1_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.000990 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	785	Shared Neighborhood Hits	4
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

PLXB1_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.008924 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

TCRG1_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.018891 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	929	Shared Neighborhood Hits	9
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.018615 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	947	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

ZN646_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.001721 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	813	Shared Neighborhood Hits	4
SwissProt Accessions	O15015	Gene names	ZNF646, KIAA0296
Domain Architecture	No domain graphic available
Description	Zinc finger protein 646.

FEZ1_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.016479 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0X8	Gene names	Fez1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

KNTC2_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.007841 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	692	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

PNKP_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.019043 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

CD2L7_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.002375 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	1275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CTDP1_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.015180 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	416	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

PSL1_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.025665 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	650	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

AKP8L_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.017457 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

RERE_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.008273 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	785	Shared Neighborhood Hits	10
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SOS1_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.008365 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

APCD1_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.022064 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U128, Q3TA99	Gene names	Apcdd1, Drapc1
Domain Architecture	No domain graphic available
Description	Protein APCDD1 precursor (Adenomatosis polyposis coli down-regulated 1 protein homolog).

BRD4_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.012992 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	851	Shared Neighborhood Hits	14
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CN092_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.008811 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

HME1_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.002061 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	384	Shared Neighborhood Hits	2
SwissProt Accessions	Q05925	Gene names	EN1
Domain Architecture
Description	Homeobox protein engrailed-1 (Hu-En-1).

IP6K1_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.064608 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q92551, Q7L3I7, Q96E38	Gene names	IHPK1, IP6K1, KIAA0263
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).

IP6K1_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.064662 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PD10, Q9QXV6	Gene names	Ihpk1, Ip6k1
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).

KIF4A_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.003499 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	1159	Shared Neighborhood Hits	9
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MEFV_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.002865 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

PELP1_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.022488 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	596	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

SET1A_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.006923 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	690	Shared Neighborhood Hits	7
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SYP2L_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.011698 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	400	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

TMC2_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.008171 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	249	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4P4	Gene names	Tmc2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

Hits sorted by NC score

IP3KA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

IP3KA_MOUSE
NC score	0.990844 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R071	Gene names	Itpka
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

IP3KC_HUMAN
NC score	0.951304 (rank : 3)	θ value	3.00075e-104 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q96DU7, Q9UE25, Q9Y475	Gene names	ITPKC, IP3KC
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (InsP 3-kinase C) (IP3K-C).

IP3KC_MOUSE
NC score	0.950589 (rank : 4)	θ value	4.6295e-105 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TS72, Q3U384	Gene names	Itpkc
Domain Architecture	No domain graphic available
Description	Inositol-trisphosphate 3-kinase C (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase C) (IP3K-C).

IP3KB_HUMAN
NC score	0.938154 (rank : 5)	θ value	4.77967e-110 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	124	Shared Neighborhood Hits	11
SwissProt Accessions	P27987, Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47	Gene names	ITPKB
Domain Architecture
Description	Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase B) (IP3K B) (IP3 3-kinase B) (IP3K-B).

IPMK_HUMAN
NC score	0.180590 (rank : 6)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NFU5	Gene names	IPMK, IMPK
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

IPMK_MOUSE
NC score	0.180411 (rank : 7)	θ value	0.0193708 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	17	Shared Neighborhood Hits	13
SwissProt Accessions	Q7TT16, Q8BZ11, Q8BZA8, Q9CWM9	Gene names	Ipmk, Impk
Domain Architecture	No domain graphic available
Description	Inositol polyphosphate multikinase (EC 2.7.1.151) (Inositol 1,3,4,6- tetrakisphosphate 5-kinase).

IP6K3_HUMAN
NC score	0.120703 (rank : 8)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	19	Shared Neighborhood Hits	12
SwissProt Accessions	Q96PC2, Q96MQ9	Gene names	IHPK3, IP6K3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

IP6K3_MOUSE
NC score	0.110142 (rank : 9)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BWD2	Gene names	Ihpk3, Ip6k3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

IP6K2_HUMAN
NC score	0.094266 (rank : 10)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UHH9, Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6	Gene names	IHPK2, IP6K2
Domain Architecture	No domain graphic available
Description	Inositol hexakisphosphate kinase 2 (EC 2.7.4.21) (InsP6 kinase 2) (Inositol hexakisphosphate kinase 2) (P(i)-uptake stimulator) (PiUS).

IP6K2_MOUSE
NC score	0.093158 (rank : 11)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q80V72	Gene names	Ihpk2, Ip6k2
Domain Architecture	No domain graphic available
Description	Inositol hexakisphosphate kinase 2 (EC 2.7.4.21) (InsP6 kinase 2) (Inositol hexakisphosphate kinase 2) (P(i)-uptake stimulator) (PiUS).

IP6K1_MOUSE
NC score	0.064662 (rank : 12)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PD10, Q9QXV6	Gene names	Ihpk1, Ip6k1
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).

IP6K1_HUMAN
NC score	0.064608 (rank : 13)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q92551, Q7L3I7, Q96E38	Gene names	IHPK1, IP6K1, KIAA0263
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 1 (EC 2.7.4.21) (InsP6 kinase 1) (Inositol hexakisphosphate kinase 1).

RBM12_HUMAN
NC score	0.036689 (rank : 14)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	298	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

PELP1_MOUSE
NC score	0.035603 (rank : 15)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	709	Shared Neighborhood Hits	18
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RBM12_MOUSE
NC score	0.035126 (rank : 16)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	313	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

YLPM1_MOUSE
NC score	0.028693 (rank : 17)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	505	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

PSL1_HUMAN
NC score	0.025665 (rank : 18)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	650	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

CJ078_MOUSE
NC score	0.024576 (rank : 19)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	559	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

SFR15_HUMAN
NC score	0.023836 (rank : 20)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

LRC34_MOUSE
NC score	0.022788 (rank : 21)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DAM1	Gene names	Lrrc34
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 34.

PELP1_HUMAN
NC score	0.022488 (rank : 22)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	596	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

APCD1_MOUSE
NC score	0.022064 (rank : 23)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U128, Q3TA99	Gene names	Apcdd1, Drapc1
Domain Architecture	No domain graphic available
Description	Protein APCDD1 precursor (Adenomatosis polyposis coli down-regulated 1 protein homolog).

ERAL_HUMAN
NC score	0.021737 (rank : 24)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	O75616, O75617, Q8WUY4, Q96LE2, Q96TC0	Gene names	ERAL1, HERA
Domain Architecture	No domain graphic available
Description	GTP-binding protein era homolog (hERA) (ERA-W) (Conserved ERA-like GTPase) (CEGA).

FMN1A_MOUSE
NC score	0.021249 (rank : 25)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	423	Shared Neighborhood Hits	9
SwissProt Accessions	Q05860	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoforms I/II/III (Limb deformity protein).

FMN1B_MOUSE
NC score	0.020753 (rank : 26)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	447	Shared Neighborhood Hits	10
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

GGN_MOUSE
NC score	0.019798 (rank : 27)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	311	Shared Neighborhood Hits	5
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

WASL_MOUSE
NC score	0.019753 (rank : 28)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	339	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YD9	Gene names	Wasl
Domain Architecture	No domain graphic available
Description	Neural Wiskott-Aldrich syndrome protein (N-WASP).

PNKP_MOUSE
NC score	0.019043 (rank : 29)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

TCRG1_HUMAN
NC score	0.018891 (rank : 30)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	929	Shared Neighborhood Hits	9
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
NC score	0.018615 (rank : 31)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	947	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

AKP8L_MOUSE
NC score	0.017457 (rank : 32)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0L7	Gene names	Akap8l, Nakap95
Domain Architecture
Description	A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A- kinase-anchoring protein 95) (Neighbor of AKAP95).

MCATL_HUMAN
NC score	0.016578 (rank : 33)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N8R3	Gene names	SLC25A29, C14orf69
Domain Architecture
Description	Mitochondrial carnitine/acylcarnitine carrier protein CACL (CACT-like) (Solute carrier family 25 member 29).

FEZ1_MOUSE
NC score	0.016479 (rank : 34)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K0X8	Gene names	Fez1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

BRD4_MOUSE
NC score	0.016209 (rank : 35)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	845	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CTDP1_HUMAN
NC score	0.015180 (rank : 36)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	416	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

PRELP_HUMAN
NC score	0.013961 (rank : 37)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	P51888	Gene names	PRELP
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

PRELP_MOUSE
NC score	0.013486 (rank : 38)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JK53	Gene names	Prelp
Domain Architecture
Description	Prolargin precursor (Proline-arginine-rich end leucine-rich repeat protein).

BRD4_HUMAN
NC score	0.012992 (rank : 39)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	851	Shared Neighborhood Hits	14
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

AAK1_HUMAN
NC score	0.012385 (rank : 40)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	1077	Shared Neighborhood Hits	10
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

SYP2L_HUMAN
NC score	0.011698 (rank : 41)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	400	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

E41L5_HUMAN
NC score	0.011643 (rank : 42)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

OBSCN_HUMAN
NC score	0.009838 (rank : 43)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	1931	Shared Neighborhood Hits	16
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

FZD8_HUMAN
NC score	0.009375 (rank : 44)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

TRHY_HUMAN
NC score	0.009081 (rank : 45)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	1385	Shared Neighborhood Hits	11
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

PLXB1_MOUSE
NC score	0.008924 (rank : 46)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	259	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

CN092_MOUSE
NC score	0.008811 (rank : 47)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

SOS1_HUMAN
NC score	0.008365 (rank : 48)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

RERE_MOUSE
NC score	0.008273 (rank : 49)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	785	Shared Neighborhood Hits	10
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TMC2_MOUSE
NC score	0.008171 (rank : 50)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	249	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4P4	Gene names	Tmc2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

KNTC2_MOUSE
NC score	0.007841 (rank : 51)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	692	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

WNK2_HUMAN
NC score	0.007802 (rank : 52)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	1407	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

SET1A_HUMAN
NC score	0.006923 (rank : 53)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	690	Shared Neighborhood Hits	7
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

FOG1_HUMAN
NC score	0.004877 (rank : 54)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	981	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

KIF4A_HUMAN
NC score	0.003499 (rank : 55)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	1159	Shared Neighborhood Hits	9
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MEFV_HUMAN
NC score	0.002865 (rank : 56)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

CD2L7_HUMAN
NC score	0.002375 (rank : 57)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	1275	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

HME1_HUMAN
NC score	0.002061 (rank : 58)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	384	Shared Neighborhood Hits	2
SwissProt Accessions	Q05925	Gene names	EN1
Domain Architecture
Description	Homeobox protein engrailed-1 (Hu-En-1).

ZN646_HUMAN
NC score	0.001721 (rank : 59)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	813	Shared Neighborhood Hits	4
SwissProt Accessions	O15015	Gene names	ZNF646, KIAA0296
Domain Architecture	No domain graphic available
Description	Zinc finger protein 646.

MTF1_MOUSE
NC score	0.000990 (rank : 60)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	785	Shared Neighborhood Hits	4
SwissProt Accessions	Q07243	Gene names	Mtf1, Mtf-1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).