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Network neighborhood for query Sequence : PNKP_MOUSE

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PNKP_MOUSE
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PNKP_HUMAN
θ value	0 (rank : 1)	NC score	0.993455 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q96T60, Q9P1V2, Q9UKU8, Q9UNF8	Gene names	PNKP
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

PNKP_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

APTX_HUMAN
θ value	4.16044e-13 (rank : 3)	NC score	0.517739 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z2E3, Q5T781, Q7Z2F3, Q7Z336, Q7Z5R5, Q7Z6V7, Q7Z6V8, Q9NXM5	Gene names	APTX
Domain Architecture
Description	Aprataxin (Forkhead-associated domain histidine triad-like protein) (FHA-HIT).

APTX_MOUSE
θ value	4.16044e-13 (rank : 4)	NC score	0.514065 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQC5, Q8BPA7, Q8C2B5, Q8K3D1, Q9CQ59	Gene names	Aptx
Domain Architecture
Description	Aprataxin homolog (Forkhead-associated domain histidine triad-like protein) (FHA-HIT).

HNRPU_HUMAN
θ value	0.0330416 (rank : 5)	NC score	0.138865 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

CB013_HUMAN
θ value	0.0736092 (rank : 6)	NC score	0.130889 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IW19, Q53P47, Q53PB9, Q53QU0	Gene names	C2orf13
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13.

HNRL1_HUMAN
θ value	0.0736092 (rank : 7)	NC score	0.108022 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
θ value	0.0736092 (rank : 8)	NC score	0.107655 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

DHX34_HUMAN
θ value	0.813845 (rank : 9)	NC score	0.051368 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX34_MOUSE
θ value	0.813845 (rank : 10)	NC score	0.043730 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	235	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX35_HUMAN
θ value	1.81305 (rank : 11)	NC score	0.029690 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

CB013_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.076712 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D842, Q8BZL5, Q99LX6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13 homolog.

IP3KA_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.019043 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

SEM5B_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.009330 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

DHX8_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.025000 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

SEM5B_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.008837 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

CXA8_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.005471 (rank : 18)
Query Neighborhood Hits	17	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	P48165, Q9NP25	Gene names	GJA8
Domain Architecture
Description	Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70).

HINT1_HUMAN
θ value	θ > 10 (rank : 18)	NC score	0.051832 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P49773, Q9H5W8	Gene names	HINT1, HINT, PKCI1, PRKCNH1
Domain Architecture
Description	Histidine triad nucleotide-binding protein 1 (Adenosine 5'- monophosphoramidase) (Protein kinase C inhibitor 1) (Protein kinase C- interacting protein 1) (PKCI-1).

Hits sorted by NC score

PNKP_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

PNKP_HUMAN
NC score	0.993455 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	9
SwissProt Accessions	Q96T60, Q9P1V2, Q9UKU8, Q9UNF8	Gene names	PNKP
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

APTX_HUMAN
NC score	0.517739 (rank : 3)	θ value	4.16044e-13 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	24	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z2E3, Q5T781, Q7Z2F3, Q7Z336, Q7Z5R5, Q7Z6V7, Q7Z6V8, Q9NXM5	Gene names	APTX
Domain Architecture
Description	Aprataxin (Forkhead-associated domain histidine triad-like protein) (FHA-HIT).

APTX_MOUSE
NC score	0.514065 (rank : 4)	θ value	4.16044e-13 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQC5, Q8BPA7, Q8C2B5, Q8K3D1, Q9CQ59	Gene names	Aptx
Domain Architecture
Description	Aprataxin homolog (Forkhead-associated domain histidine triad-like protein) (FHA-HIT).

HNRPU_HUMAN
NC score	0.138865 (rank : 5)	θ value	0.0330416 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q00839, O75507, Q96HY9	Gene names	HNRPU, SAFA, U21.1
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (Scaffold attachment factor A) (SAF-A) (p120) (pp120).

CB013_HUMAN
NC score	0.130889 (rank : 6)	θ value	0.0736092 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IW19, Q53P47, Q53PB9, Q53QU0	Gene names	C2orf13
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13.

HNRL1_HUMAN
NC score	0.108022 (rank : 7)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BUJ2, O76022, Q6ZSZ0, Q7L8P4, Q8N6Z4, Q96G37, Q9HAL3, Q9UG75	Gene names	HNRPUL1, E1BAP5
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5).

HNRL1_MOUSE
NC score	0.107655 (rank : 8)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

CB013_MOUSE
NC score	0.076712 (rank : 9)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D842, Q8BZL5, Q99LX6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13 homolog.

HINT1_HUMAN
NC score	0.051832 (rank : 10)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	17	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P49773, Q9H5W8	Gene names	HINT1, HINT, PKCI1, PRKCNH1
Domain Architecture
Description	Histidine triad nucleotide-binding protein 1 (Adenosine 5'- monophosphoramidase) (Protein kinase C inhibitor 1) (Protein kinase C- interacting protein 1) (PKCI-1).

DHX34_HUMAN
NC score	0.051368 (rank : 11)	θ value	0.813845 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q14147	Gene names	DHX34, DDX34, KIAA0134
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX34_MOUSE
NC score	0.043730 (rank : 12)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	235	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DBV3	Gene names	Dhx34, Ddx34, Kiaa0134
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX34 (EC 3.6.1.-) (DEAH box protein 34).

DHX35_HUMAN
NC score	0.029690 (rank : 13)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	46	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

DHX8_HUMAN
NC score	0.025000 (rank : 14)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	86	Shared Neighborhood Hits	5
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

IP3KA_HUMAN
NC score	0.019043 (rank : 15)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	P23677, Q8TAN3	Gene names	ITPKA
Domain Architecture
Description	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5- trisphosphate 3-kinase A) (IP3K A) (IP3 3-kinase A).

SEM5B_MOUSE
NC score	0.009330 (rank : 16)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5B_HUMAN
NC score	0.008837 (rank : 17)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	178	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

CXA8_HUMAN
NC score	0.005471 (rank : 18)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	P48165, Q9NP25	Gene names	GJA8
Domain Architecture
Description	Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70).