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Network neighborhood for query Sequence : SEM5B_MOUSE

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SEM5B_MOUSE
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SEM5A_HUMAN
θ value	0 (rank : 1)	NC score	0.994034 (rank : 4)
Query Neighborhood Hits	190	Target Neighborhood Hits	177	Shared Neighborhood Hits	146
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	0 (rank : 2)	NC score	0.994611 (rank : 3)
Query Neighborhood Hits	190	Target Neighborhood Hits	162	Shared Neighborhood Hits	141
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_HUMAN
θ value	0 (rank : 3)	NC score	0.998299 (rank : 2)
Query Neighborhood Hits	190	Target Neighborhood Hits	178	Shared Neighborhood Hits	163
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5B_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	190	Target Neighborhood Hits	190	Shared Neighborhood Hits	190
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM6D_MOUSE
θ value	8.20983e-86 (rank : 5)	NC score	0.800108 (rank : 14)
Query Neighborhood Hits	190	Target Neighborhood Hits	161	Shared Neighborhood Hits	53
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6D_HUMAN
θ value	5.32145e-85 (rank : 6)	NC score	0.799368 (rank : 16)
Query Neighborhood Hits	190	Target Neighborhood Hits	169	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6A_MOUSE
θ value	5.69867e-79 (rank : 7)	NC score	0.801163 (rank : 11)
Query Neighborhood Hits	190	Target Neighborhood Hits	96	Shared Neighborhood Hits	53
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SEM6B_HUMAN
θ value	9.7205e-79 (rank : 8)	NC score	0.801643 (rank : 8)
Query Neighborhood Hits	190	Target Neighborhood Hits	187	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SEM6A_HUMAN
θ value	8.22888e-78 (rank : 9)	NC score	0.801165 (rank : 10)
Query Neighborhood Hits	190	Target Neighborhood Hits	96	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM6B_MOUSE
θ value	1.40363e-77 (rank : 10)	NC score	0.798494 (rank : 17)
Query Neighborhood Hits	190	Target Neighborhood Hits	200	Shared Neighborhood Hits	53
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SEM6C_HUMAN
θ value	3.12697e-77 (rank : 11)	NC score	0.802093 (rank : 7)
Query Neighborhood Hits	190	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6C_MOUSE
θ value	4.51533e-76 (rank : 12)	NC score	0.787576 (rank : 34)
Query Neighborhood Hits	190	Target Neighborhood Hits	352	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM3A_MOUSE
θ value	5.8972e-76 (rank : 13)	NC score	0.789951 (rank : 29)
Query Neighborhood Hits	190	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	O08665, Q5BL08, Q62180, Q62215	Gene names	Sema3a, Semad, SemD
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III) (Semaphorin D) (Sema D).

SEM3A_HUMAN
θ value	7.70199e-76 (rank : 14)	NC score	0.790432 (rank : 28)
Query Neighborhood Hits	190	Target Neighborhood Hits	78	Shared Neighborhood Hits	54
SwissProt Accessions	Q14563	Gene names	SEMA3A
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III).

HMCN1_HUMAN
θ value	2.47765e-74 (rank : 15)	NC score	0.283896 (rank : 122)
Query Neighborhood Hits	190	Target Neighborhood Hits	983	Shared Neighborhood Hits	127
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

SEM3B_HUMAN
θ value	1.7756e-72 (rank : 16)	NC score	0.794632 (rank : 19)
Query Neighborhood Hits	190	Target Neighborhood Hits	76	Shared Neighborhood Hits	54
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

SEM4C_HUMAN
θ value	6.31527e-70 (rank : 17)	NC score	0.802102 (rank : 6)
Query Neighborhood Hits	190	Target Neighborhood Hits	84	Shared Neighborhood Hits	54
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SEM4C_MOUSE
θ value	5.34618e-69 (rank : 18)	NC score	0.799742 (rank : 15)
Query Neighborhood Hits	190	Target Neighborhood Hits	77	Shared Neighborhood Hits	54
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM4A_HUMAN
θ value	1.5555e-68 (rank : 19)	NC score	0.803379 (rank : 5)
Query Neighborhood Hits	190	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM3F_HUMAN
θ value	2.65329e-68 (rank : 20)	NC score	0.795130 (rank : 18)
Query Neighborhood Hits	190	Target Neighborhood Hits	100	Shared Neighborhood Hits	61
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEM3F_MOUSE
θ value	2.65329e-68 (rank : 21)	NC score	0.793432 (rank : 24)
Query Neighborhood Hits	190	Target Neighborhood Hits	86	Shared Neighborhood Hits	55
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEM3E_HUMAN
θ value	7.71989e-68 (rank : 22)	NC score	0.789412 (rank : 30)
Query Neighborhood Hits	190	Target Neighborhood Hits	73	Shared Neighborhood Hits	53
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

SEM3E_MOUSE
θ value	1.71981e-67 (rank : 23)	NC score	0.788713 (rank : 33)
Query Neighborhood Hits	190	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM4D_MOUSE
θ value	1.71981e-67 (rank : 24)	NC score	0.793679 (rank : 22)
Query Neighborhood Hits	190	Target Neighborhood Hits	143	Shared Neighborhood Hits	54
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SEM4D_HUMAN
θ value	1.11475e-66 (rank : 25)	NC score	0.793176 (rank : 26)
Query Neighborhood Hits	190	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

SEM3B_MOUSE
θ value	1.45591e-66 (rank : 26)	NC score	0.793214 (rank : 25)
Query Neighborhood Hits	190	Target Neighborhood Hits	75	Shared Neighborhood Hits	53
SwissProt Accessions	Q62177	Gene names	Sema3b, Sema, Semaa
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin A) (Sema A).

SEM3C_MOUSE
θ value	2.4834e-66 (rank : 27)	NC score	0.794385 (rank : 20)
Query Neighborhood Hits	190	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3D_HUMAN
θ value	7.2256e-66 (rank : 28)	NC score	0.786854 (rank : 35)
Query Neighborhood Hits	190	Target Neighborhood Hits	104	Shared Neighborhood Hits	53
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

SEM3C_HUMAN
θ value	1.2325e-65 (rank : 29)	NC score	0.794299 (rank : 21)
Query Neighborhood Hits	190	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3D_MOUSE
θ value	1.6097e-65 (rank : 30)	NC score	0.785423 (rank : 36)
Query Neighborhood Hits	190	Target Neighborhood Hits	97	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

SEM4B_MOUSE
θ value	2.74572e-65 (rank : 31)	NC score	0.801145 (rank : 12)
Query Neighborhood Hits	190	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q62179, Q4PKI6, Q69ZB7	Gene names	Sema4b, Kiaa1745, Semac, SemC
Domain Architecture	No domain graphic available
Description	Semaphorin-4B precursor (Semaphorin C) (Sema C).

SEM4A_MOUSE
θ value	1.77973e-64 (rank : 32)	NC score	0.801410 (rank : 9)
Query Neighborhood Hits	190	Target Neighborhood Hits	65	Shared Neighborhood Hits	53
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4B_HUMAN
θ value	6.76295e-64 (rank : 33)	NC score	0.800516 (rank : 13)
Query Neighborhood Hits	190	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NPR2, Q6UXE3, Q8WVP9, Q96FK5, Q9C0B8, Q9H691, Q9NPM8, Q9NPN0	Gene names	SEMA4B, KIAA1745
Domain Architecture
Description	Semaphorin-4B precursor.

SEM4F_MOUSE
θ value	7.49467e-55 (rank : 34)	NC score	0.793617 (rank : 23)
Query Neighborhood Hits	190	Target Neighborhood Hits	59	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

SEM4F_HUMAN
θ value	4.11246e-53 (rank : 35)	NC score	0.792041 (rank : 27)
Query Neighborhood Hits	190	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	O95754, Q9NS35	Gene names	SEMA4F, SEMAM, SEMAW
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W) (Semaphorin M) (Sema M).

SEM4G_HUMAN
θ value	6.56568e-51 (rank : 36)	NC score	0.788892 (rank : 32)
Query Neighborhood Hits	190	Target Neighborhood Hits	88	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NTN9, Q9HCF3	Gene names	SEMA4G, KIAA1619
Domain Architecture
Description	Semaphorin-4G precursor.

SEM4G_MOUSE
θ value	3.2585e-50 (rank : 37)	NC score	0.789214 (rank : 31)
Query Neighborhood Hits	190	Target Neighborhood Hits	99	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SSPO_MOUSE
θ value	4.70527e-49 (rank : 38)	NC score	0.393289 (rank : 94)
Query Neighborhood Hits	190	Target Neighborhood Hits	800	Shared Neighborhood Hits	130
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

PROP_MOUSE
θ value	7.51208e-47 (rank : 39)	NC score	0.627233 (rank : 40)
Query Neighborhood Hits	190	Target Neighborhood Hits	165	Shared Neighborhood Hits	93
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROP_HUMAN
θ value	1.67352e-46 (rank : 40)	NC score	0.629151 (rank : 39)
Query Neighborhood Hits	190	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

BAI1_HUMAN
θ value	8.04462e-41 (rank : 41)	NC score	0.462638 (rank : 52)
Query Neighborhood Hits	190	Target Neighborhood Hits	375	Shared Neighborhood Hits	96
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	2.34062e-40 (rank : 42)	NC score	0.463707 (rank : 50)
Query Neighborhood Hits	190	Target Neighborhood Hits	340	Shared Neighborhood Hits	95
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_MOUSE
θ value	1.46948e-34 (rank : 43)	NC score	0.457027 (rank : 55)
Query Neighborhood Hits	190	Target Neighborhood Hits	323	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
θ value	3.27365e-34 (rank : 44)	NC score	0.457647 (rank : 54)
Query Neighborhood Hits	190	Target Neighborhood Hits	332	Shared Neighborhood Hits	95
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

SEM7A_MOUSE
θ value	1.79631e-32 (rank : 45)	NC score	0.771057 (rank : 37)
Query Neighborhood Hits	190	Target Neighborhood Hits	64	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QUR8, O88371	Gene names	Sema7a, Cd108, Semal, Semk1
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (CD108 antigen) (CDw108).

TSP1_MOUSE
θ value	8.91499e-32 (rank : 46)	NC score	0.435277 (rank : 64)
Query Neighborhood Hits	190	Target Neighborhood Hits	396	Shared Neighborhood Hits	117
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_HUMAN
θ value	1.16434e-31 (rank : 47)	NC score	0.435480 (rank : 63)
Query Neighborhood Hits	190	Target Neighborhood Hits	389	Shared Neighborhood Hits	117
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_MOUSE
θ value	1.98606e-31 (rank : 48)	NC score	0.444429 (rank : 58)
Query Neighborhood Hits	190	Target Neighborhood Hits	352	Shared Neighborhood Hits	113
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_HUMAN
θ value	2.19584e-30 (rank : 49)	NC score	0.441720 (rank : 60)
Query Neighborhood Hits	190	Target Neighborhood Hits	359	Shared Neighborhood Hits	115
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

SEM7A_HUMAN
θ value	3.74554e-30 (rank : 50)	NC score	0.769661 (rank : 38)
Query Neighborhood Hits	190	Target Neighborhood Hits	67	Shared Neighborhood Hits	53
SwissProt Accessions	O75326	Gene names	SEMA7A, CD108, SEMAL
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (John-Milton-Hargen human blood group Ag) (JMH blood group antigen) (CD108 antigen) (CDw108).

BAI3_HUMAN
θ value	1.08979e-29 (rank : 51)	NC score	0.460434 (rank : 53)
Query Neighborhood Hits	190	Target Neighborhood Hits	246	Shared Neighborhood Hits	91
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	4.14116e-29 (rank : 52)	NC score	0.463547 (rank : 51)
Query Neighborhood Hits	190	Target Neighborhood Hits	250	Shared Neighborhood Hits	93
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

UNC5D_HUMAN
θ value	3.39556e-23 (rank : 53)	NC score	0.468587 (rank : 48)
Query Neighborhood Hits	190	Target Neighborhood Hits	267	Shared Neighborhood Hits	84
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	4.43474e-23 (rank : 54)	NC score	0.466800 (rank : 49)
Query Neighborhood Hits	190	Target Neighborhood Hits	268	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5A_MOUSE
θ value	5.79196e-23 (rank : 55)	NC score	0.486111 (rank : 43)
Query Neighborhood Hits	190	Target Neighborhood Hits	203	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5C_MOUSE
θ value	5.79196e-23 (rank : 56)	NC score	0.471207 (rank : 46)
Query Neighborhood Hits	190	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5B_MOUSE
θ value	7.56453e-23 (rank : 57)	NC score	0.484328 (rank : 44)
Query Neighborhood Hits	190	Target Neighborhood Hits	226	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
θ value	9.87957e-23 (rank : 58)	NC score	0.483755 (rank : 45)
Query Neighborhood Hits	190	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5C_HUMAN
θ value	9.87957e-23 (rank : 59)	NC score	0.470661 (rank : 47)
Query Neighborhood Hits	190	Target Neighborhood Hits	226	Shared Neighborhood Hits	81
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

SPON1_MOUSE
θ value	2.87452e-22 (rank : 60)	NC score	0.530205 (rank : 41)
Query Neighborhood Hits	190	Target Neighborhood Hits	123	Shared Neighborhood Hits	90
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
θ value	5.42112e-21 (rank : 61)	NC score	0.527660 (rank : 42)
Query Neighborhood Hits	190	Target Neighborhood Hits	117	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

ATS9_HUMAN
θ value	4.74913e-17 (rank : 62)	NC score	0.438574 (rank : 62)
Query Neighborhood Hits	190	Target Neighborhood Hits	219	Shared Neighborhood Hits	99
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS20_HUMAN
θ value	2.35696e-16 (rank : 63)	NC score	0.425861 (rank : 74)
Query Neighborhood Hits	190	Target Neighborhood Hits	192	Shared Neighborhood Hits	94
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS18_MOUSE
θ value	4.44505e-15 (rank : 64)	NC score	0.434099 (rank : 65)
Query Neighborhood Hits	190	Target Neighborhood Hits	163	Shared Neighborhood Hits	88
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_HUMAN
θ value	9.90251e-15 (rank : 65)	NC score	0.429740 (rank : 68)
Query Neighborhood Hits	190	Target Neighborhood Hits	169	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS20_MOUSE
θ value	1.29331e-14 (rank : 66)	NC score	0.432065 (rank : 66)
Query Neighborhood Hits	190	Target Neighborhood Hits	225	Shared Neighborhood Hits	95
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS8_HUMAN
θ value	2.88119e-14 (rank : 67)	NC score	0.427104 (rank : 72)
Query Neighborhood Hits	190	Target Neighborhood Hits	145	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

PLXA4_HUMAN
θ value	2.88119e-14 (rank : 68)	NC score	0.354943 (rank : 102)
Query Neighborhood Hits	190	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

ATS16_HUMAN
θ value	4.91457e-14 (rank : 69)	NC score	0.428459 (rank : 70)
Query Neighborhood Hits	190	Target Neighborhood Hits	208	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS15_HUMAN
θ value	1.42992e-13 (rank : 70)	NC score	0.418240 (rank : 83)
Query Neighborhood Hits	190	Target Neighborhood Hits	151	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS16_MOUSE
θ value	2.43908e-13 (rank : 71)	NC score	0.429378 (rank : 69)
Query Neighborhood Hits	190	Target Neighborhood Hits	179	Shared Neighborhood Hits	87
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS14_HUMAN
θ value	3.18553e-13 (rank : 72)	NC score	0.422751 (rank : 79)
Query Neighborhood Hits	190	Target Neighborhood Hits	382	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS8_MOUSE
θ value	5.43371e-13 (rank : 73)	NC score	0.431213 (rank : 67)
Query Neighborhood Hits	190	Target Neighborhood Hits	139	Shared Neighborhood Hits	84
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS17_HUMAN
θ value	7.09661e-13 (rank : 74)	NC score	0.427975 (rank : 71)
Query Neighborhood Hits	190	Target Neighborhood Hits	194	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

PLXA4_MOUSE
θ value	7.09661e-13 (rank : 75)	NC score	0.353172 (rank : 103)
Query Neighborhood Hits	190	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXB3_MOUSE
θ value	7.09661e-13 (rank : 76)	NC score	0.316219 (rank : 118)
Query Neighborhood Hits	190	Target Neighborhood Hits	94	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

ATS13_HUMAN
θ value	1.2105e-12 (rank : 77)	NC score	0.444041 (rank : 59)
Query Neighborhood Hits	190	Target Neighborhood Hits	238	Shared Neighborhood Hits	88
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS2_MOUSE
θ value	1.2105e-12 (rank : 78)	NC score	0.422772 (rank : 78)
Query Neighborhood Hits	190	Target Neighborhood Hits	179	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS12_HUMAN
θ value	1.58096e-12 (rank : 79)	NC score	0.416780 (rank : 86)
Query Neighborhood Hits	190	Target Neighborhood Hits	251	Shared Neighborhood Hits	88
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS4_HUMAN
θ value	1.58096e-12 (rank : 80)	NC score	0.426097 (rank : 73)
Query Neighborhood Hits	190	Target Neighborhood Hits	138	Shared Neighborhood Hits	80
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS12_MOUSE
θ value	2.0648e-12 (rank : 81)	NC score	0.417518 (rank : 84)
Query Neighborhood Hits	190	Target Neighborhood Hits	220	Shared Neighborhood Hits	89
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS4_MOUSE
θ value	2.69671e-12 (rank : 82)	NC score	0.425019 (rank : 76)
Query Neighborhood Hits	190	Target Neighborhood Hits	145	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS5_MOUSE
θ value	2.69671e-12 (rank : 83)	NC score	0.407675 (rank : 90)
Query Neighborhood Hits	190	Target Neighborhood Hits	147	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS7_HUMAN
θ value	4.59992e-12 (rank : 84)	NC score	0.410225 (rank : 89)
Query Neighborhood Hits	190	Target Neighborhood Hits	169	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS5_HUMAN
θ value	6.00763e-12 (rank : 85)	NC score	0.403199 (rank : 92)
Query Neighborhood Hits	190	Target Neighborhood Hits	141	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS1_HUMAN
θ value	7.84624e-12 (rank : 86)	NC score	0.417354 (rank : 85)
Query Neighborhood Hits	190	Target Neighborhood Hits	159	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS1_MOUSE
θ value	1.02475e-11 (rank : 87)	NC score	0.418262 (rank : 82)
Query Neighborhood Hits	190	Target Neighborhood Hits	158	Shared Neighborhood Hits	87
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS6_HUMAN
θ value	1.02475e-11 (rank : 88)	NC score	0.414929 (rank : 87)
Query Neighborhood Hits	190	Target Neighborhood Hits	141	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS19_MOUSE
θ value	2.28291e-11 (rank : 89)	NC score	0.404736 (rank : 91)
Query Neighborhood Hits	190	Target Neighborhood Hits	188	Shared Neighborhood Hits	82
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS2_HUMAN
θ value	2.98157e-11 (rank : 90)	NC score	0.423327 (rank : 77)
Query Neighborhood Hits	190	Target Neighborhood Hits	179	Shared Neighborhood Hits	82
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS19_HUMAN
θ value	3.89403e-11 (rank : 91)	NC score	0.398997 (rank : 93)
Query Neighborhood Hits	190	Target Neighborhood Hits	203	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

PLXB3_HUMAN
θ value	6.64225e-11 (rank : 92)	NC score	0.310809 (rank : 119)
Query Neighborhood Hits	190	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

ATS13_MOUSE
θ value	1.133e-10 (rank : 93)	NC score	0.438923 (rank : 61)
Query Neighborhood Hits	190	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATL3_HUMAN
θ value	2.52405e-10 (rank : 94)	NC score	0.383924 (rank : 96)
Query Neighborhood Hits	190	Target Neighborhood Hits	414	Shared Neighborhood Hits	90
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATS3_HUMAN
θ value	4.30538e-10 (rank : 95)	NC score	0.410817 (rank : 88)
Query Neighborhood Hits	190	Target Neighborhood Hits	179	Shared Neighborhood Hits	87
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

PLXA2_HUMAN
θ value	7.34386e-10 (rank : 96)	NC score	0.337561 (rank : 108)
Query Neighborhood Hits	190	Target Neighborhood Hits	100	Shared Neighborhood Hits	56
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

PLXB2_HUMAN
θ value	1.63604e-09 (rank : 97)	NC score	0.372307 (rank : 98)
Query Neighborhood Hits	190	Target Neighborhood Hits	94	Shared Neighborhood Hits	55
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

PLXB1_HUMAN
θ value	3.64472e-09 (rank : 98)	NC score	0.325465 (rank : 114)
Query Neighborhood Hits	190	Target Neighborhood Hits	360	Shared Neighborhood Hits	60
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

ATL1_HUMAN
θ value	1.38499e-08 (rank : 99)	NC score	0.420190 (rank : 80)
Query Neighborhood Hits	190	Target Neighborhood Hits	93	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

CO6_HUMAN
θ value	1.80886e-08 (rank : 100)	NC score	0.356149 (rank : 101)
Query Neighborhood Hits	190	Target Neighborhood Hits	331	Shared Neighborhood Hits	103
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CILP2_HUMAN
θ value	3.08544e-08 (rank : 101)	NC score	0.331282 (rank : 111)
Query Neighborhood Hits	190	Target Neighborhood Hits	307	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

ATL1_MOUSE
θ value	5.26297e-08 (rank : 102)	NC score	0.419181 (rank : 81)
Query Neighborhood Hits	190	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL2_HUMAN
θ value	8.97725e-08 (rank : 103)	NC score	0.452128 (rank : 56)
Query Neighborhood Hits	190	Target Neighborhood Hits	125	Shared Neighborhood Hits	86
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

CO8A_HUMAN
θ value	8.97725e-08 (rank : 104)	NC score	0.349765 (rank : 104)
Query Neighborhood Hits	190	Target Neighborhood Hits	200	Shared Neighborhood Hits	86
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	1.53129e-07 (rank : 105)	NC score	0.346240 (rank : 105)
Query Neighborhood Hits	190	Target Neighborhood Hits	199	Shared Neighborhood Hits	84
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

PLXA2_MOUSE
θ value	1.99992e-07 (rank : 106)	NC score	0.333994 (rank : 110)
Query Neighborhood Hits	190	Target Neighborhood Hits	97	Shared Neighborhood Hits	55
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

PLXD1_HUMAN
θ value	1.99992e-07 (rank : 107)	NC score	0.298640 (rank : 121)
Query Neighborhood Hits	190	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

THSD1_HUMAN
θ value	2.61198e-07 (rank : 108)	NC score	0.391915 (rank : 95)
Query Neighborhood Hits	190	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CO8A_MOUSE
θ value	3.41135e-07 (rank : 109)	NC score	0.345894 (rank : 106)
Query Neighborhood Hits	190	Target Neighborhood Hits	182	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_MOUSE
θ value	3.41135e-07 (rank : 110)	NC score	0.364147 (rank : 100)
Query Neighborhood Hits	190	Target Neighborhood Hits	224	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

PLXB1_MOUSE
θ value	3.41135e-07 (rank : 111)	NC score	0.324120 (rank : 115)
Query Neighborhood Hits	190	Target Neighborhood Hits	259	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PLXA1_MOUSE
θ value	4.45536e-07 (rank : 112)	NC score	0.328136 (rank : 112)
Query Neighborhood Hits	190	Target Neighborhood Hits	107	Shared Neighborhood Hits	55
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

UNC5A_HUMAN
θ value	4.45536e-07 (rank : 113)	NC score	0.379443 (rank : 97)
Query Neighborhood Hits	190	Target Neighborhood Hits	198	Shared Neighborhood Hits	74
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ATL2_MOUSE
θ value	5.81887e-07 (rank : 114)	NC score	0.450714 (rank : 57)
Query Neighborhood Hits	190	Target Neighborhood Hits	137	Shared Neighborhood Hits	85
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

CO7_HUMAN
θ value	5.81887e-07 (rank : 115)	NC score	0.325604 (rank : 113)
Query Neighborhood Hits	190	Target Neighborhood Hits	278	Shared Neighborhood Hits	89
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

PLXA1_HUMAN
θ value	5.81887e-07 (rank : 116)	NC score	0.322823 (rank : 116)
Query Neighborhood Hits	190	Target Neighborhood Hits	108	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

ATL5_HUMAN
θ value	9.92553e-07 (rank : 117)	NC score	0.425838 (rank : 75)
Query Neighborhood Hits	190	Target Neighborhood Hits	103	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

PLXA3_HUMAN
θ value	4.92598e-06 (rank : 118)	NC score	0.320506 (rank : 117)
Query Neighborhood Hits	190	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	P51805	Gene names	PLXNA3, PLXN4, SEX
Domain Architecture
Description	Plexin-A3 precursor (Plexin-4) (Semaphorin receptor SEX).

CI094_HUMAN
θ value	6.43352e-06 (rank : 119)	NC score	0.309146 (rank : 120)
Query Neighborhood Hits	190	Target Neighborhood Hits	310	Shared Neighborhood Hits	72
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CILP1_MOUSE
θ value	9.29e-05 (rank : 120)	NC score	0.267960 (rank : 123)
Query Neighborhood Hits	190	Target Neighborhood Hits	282	Shared Neighborhood Hits	85
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

THSD1_MOUSE
θ value	0.000158464 (rank : 121)	NC score	0.370426 (rank : 99)
Query Neighborhood Hits	190	Target Neighborhood Hits	153	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

PLXC1_MOUSE
θ value	0.000602161 (rank : 122)	NC score	0.343358 (rank : 107)
Query Neighborhood Hits	190	Target Neighborhood Hits	84	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QZC2, Q8CGW1	Gene names	Plxnc1, Vespr
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXC1_HUMAN
θ value	0.00102713 (rank : 123)	NC score	0.334774 (rank : 109)
Query Neighborhood Hits	190	Target Neighborhood Hits	94	Shared Neighborhood Hits	55
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

VWF_HUMAN
θ value	0.00102713 (rank : 124)	NC score	0.075464 (rank : 164)
Query Neighborhood Hits	190	Target Neighborhood Hits	396	Shared Neighborhood Hits	58
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CILP1_HUMAN
θ value	0.0193708 (rank : 125)	NC score	0.253992 (rank : 124)
Query Neighborhood Hits	190	Target Neighborhood Hits	266	Shared Neighborhood Hits	82
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

FRAS1_MOUSE
θ value	0.0252991 (rank : 126)	NC score	0.084628 (rank : 153)
Query Neighborhood Hits	190	Target Neighborhood Hits	747	Shared Neighborhood Hits	93
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LRP4_MOUSE
θ value	0.0431538 (rank : 127)	NC score	0.046917 (rank : 238)
Query Neighborhood Hits	190	Target Neighborhood Hits	351	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

KRA53_HUMAN
θ value	0.0563607 (rank : 128)	NC score	0.037235 (rank : 253)
Query Neighborhood Hits	190	Target Neighborhood Hits	331	Shared Neighborhood Hits	37
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

DLL3_HUMAN
θ value	0.0961366 (rank : 129)	NC score	0.033270 (rank : 256)
Query Neighborhood Hits	190	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

TENX_HUMAN
θ value	0.0961366 (rank : 130)	NC score	0.045563 (rank : 240)
Query Neighborhood Hits	190	Target Neighborhood Hits	789	Shared Neighborhood Hits	76
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

WISP2_HUMAN
θ value	0.0961366 (rank : 131)	NC score	0.111617 (rank : 127)
Query Neighborhood Hits	190	Target Neighborhood Hits	126	Shared Neighborhood Hits	60
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

KRA59_HUMAN
θ value	0.125558 (rank : 132)	NC score	0.042612 (rank : 245)
Query Neighborhood Hits	190	Target Neighborhood Hits	310	Shared Neighborhood Hits	32
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

STAB2_HUMAN
θ value	0.125558 (rank : 133)	NC score	0.043801 (rank : 244)
Query Neighborhood Hits	190	Target Neighborhood Hits	534	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

KRA58_HUMAN
θ value	0.163984 (rank : 134)	NC score	0.039732 (rank : 249)
Query Neighborhood Hits	190	Target Neighborhood Hits	324	Shared Neighborhood Hits	33
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

SREC_HUMAN
θ value	0.163984 (rank : 135)	NC score	0.040706 (rank : 248)
Query Neighborhood Hits	190	Target Neighborhood Hits	645	Shared Neighborhood Hits	66
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

CYR61_MOUSE
θ value	0.21417 (rank : 136)	NC score	0.079094 (rank : 159)
Query Neighborhood Hits	190	Target Neighborhood Hits	156	Shared Neighborhood Hits	62
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

FRAS1_HUMAN
θ value	0.21417 (rank : 137)	NC score	0.079199 (rank : 158)
Query Neighborhood Hits	190	Target Neighborhood Hits	759	Shared Neighborhood Hits	84
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LRP4_HUMAN
θ value	0.21417 (rank : 138)	NC score	0.048373 (rank : 236)
Query Neighborhood Hits	190	Target Neighborhood Hits	355	Shared Neighborhood Hits	42
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP1B_HUMAN
θ value	0.279714 (rank : 139)	NC score	0.046551 (rank : 239)
Query Neighborhood Hits	190	Target Neighborhood Hits	602	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MET_MOUSE
θ value	0.279714 (rank : 140)	NC score	0.026754 (rank : 259)
Query Neighborhood Hits	190	Target Neighborhood Hits	844	Shared Neighborhood Hits	25
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

CELR2_HUMAN
θ value	0.47712 (rank : 141)	NC score	0.044650 (rank : 242)
Query Neighborhood Hits	190	Target Neighborhood Hits	657	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CYR61_HUMAN
θ value	0.47712 (rank : 142)	NC score	0.087264 (rank : 145)
Query Neighborhood Hits	190	Target Neighborhood Hits	159	Shared Neighborhood Hits	66
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

JAG2_HUMAN
θ value	0.62314 (rank : 143)	NC score	0.038795 (rank : 252)
Query Neighborhood Hits	190	Target Neighborhood Hits	491	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

KRA51_HUMAN
θ value	0.62314 (rank : 144)	NC score	0.060516 (rank : 203)
Query Neighborhood Hits	190	Target Neighborhood Hits	288	Shared Neighborhood Hits	46
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LRP1B_MOUSE
θ value	0.813845 (rank : 145)	NC score	0.044768 (rank : 241)
Query Neighborhood Hits	190	Target Neighborhood Hits	606	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SHPS1_HUMAN
θ value	1.06291 (rank : 146)	NC score	0.007570 (rank : 271)
Query Neighborhood Hits	190	Target Neighborhood Hits	455	Shared Neighborhood Hits	3
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

SPON2_HUMAN
θ value	1.06291 (rank : 147)	NC score	0.141730 (rank : 125)
Query Neighborhood Hits	190	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

CELR2_MOUSE
θ value	1.38821 (rank : 148)	NC score	0.039332 (rank : 250)
Query Neighborhood Hits	190	Target Neighborhood Hits	584	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

LAMC1_HUMAN
θ value	1.38821 (rank : 149)	NC score	0.017412 (rank : 263)
Query Neighborhood Hits	190	Target Neighborhood Hits	922	Shared Neighborhood Hits	49
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LRP2_HUMAN
θ value	1.38821 (rank : 150)	NC score	0.052326 (rank : 223)
Query Neighborhood Hits	190	Target Neighborhood Hits	573	Shared Neighborhood Hits	60
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ERBB3_HUMAN
θ value	1.81305 (rank : 151)	NC score	-0.001166 (rank : 279)
Query Neighborhood Hits	190	Target Neighborhood Hits	918	Shared Neighborhood Hits	19
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

KCNH2_MOUSE
θ value	1.81305 (rank : 152)	NC score	0.004565 (rank : 275)
Query Neighborhood Hits	190	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

LRP8_MOUSE
θ value	1.81305 (rank : 153)	NC score	0.047994 (rank : 237)
Query Neighborhood Hits	190	Target Neighborhood Hits	385	Shared Neighborhood Hits	49
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CRUM1_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.036799 (rank : 255)
Query Neighborhood Hits	190	Target Neighborhood Hits	457	Shared Neighborhood Hits	53
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

NOTC3_MOUSE
θ value	2.36792 (rank : 155)	NC score	0.042426 (rank : 246)
Query Neighborhood Hits	190	Target Neighborhood Hits	975	Shared Neighborhood Hits	72
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SPON2_MOUSE
θ value	2.36792 (rank : 156)	NC score	0.113470 (rank : 126)
Query Neighborhood Hits	190	Target Neighborhood Hits	42	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

CO9_MOUSE
θ value	3.0926 (rank : 157)	NC score	0.104025 (rank : 131)
Query Neighborhood Hits	190	Target Neighborhood Hits	153	Shared Neighborhood Hits	38
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

LYAM3_HUMAN
θ value	3.0926 (rank : 158)	NC score	0.016992 (rank : 264)
Query Neighborhood Hits	190	Target Neighborhood Hits	378	Shared Neighborhood Hits	36
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MK_MOUSE
θ value	3.0926 (rank : 159)	NC score	0.032817 (rank : 257)
Query Neighborhood Hits	190	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	P12025	Gene names	Mdk, Mk
Domain Architecture
Description	Midkine precursor (MK) (Retinoic acid-induced differentiation factor).

PRKN2_MOUSE
θ value	3.0926 (rank : 160)	NC score	0.015061 (rank : 266)
Query Neighborhood Hits	190	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

ADAM8_MOUSE
θ value	4.03905 (rank : 161)	NC score	0.104566 (rank : 130)
Query Neighborhood Hits	190	Target Neighborhood Hits	326	Shared Neighborhood Hits	67
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

KR132_HUMAN
θ value	4.03905 (rank : 162)	NC score	0.007219 (rank : 272)
Query Neighborhood Hits	190	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

LYAM3_MOUSE
θ value	4.03905 (rank : 163)	NC score	0.020308 (rank : 261)
Query Neighborhood Hits	190	Target Neighborhood Hits	390	Shared Neighborhood Hits	36
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

WISP1_MOUSE
θ value	4.03905 (rank : 164)	NC score	0.098045 (rank : 133)
Query Neighborhood Hits	190	Target Neighborhood Hits	123	Shared Neighborhood Hits	57
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP2_MOUSE
θ value	4.03905 (rank : 165)	NC score	0.108873 (rank : 128)
Query Neighborhood Hits	190	Target Neighborhood Hits	129	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

CRIM1_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.061100 (rank : 201)
Query Neighborhood Hits	190	Target Neighborhood Hits	362	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ELOA2_HUMAN
θ value	5.27518 (rank : 167)	NC score	0.003504 (rank : 276)
Query Neighborhood Hits	190	Target Neighborhood Hits	165	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

FBLN1_MOUSE
θ value	5.27518 (rank : 168)	NC score	0.039110 (rank : 251)
Query Neighborhood Hits	190	Target Neighborhood Hits	329	Shared Neighborhood Hits	41
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

IL4RA_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.015933 (rank : 265)
Query Neighborhood Hits	190	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

LAMA3_MOUSE
θ value	5.27518 (rank : 170)	NC score	0.014440 (rank : 267)
Query Neighborhood Hits	190	Target Neighborhood Hits	859	Shared Neighborhood Hits	54
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

MEGF6_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.051462 (rank : 227)
Query Neighborhood Hits	190	Target Neighborhood Hits	671	Shared Neighborhood Hits	75
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NOTC1_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.037172 (rank : 254)
Query Neighborhood Hits	190	Target Neighborhood Hits	906	Shared Neighborhood Hits	67
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PAPPA_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.013722 (rank : 268)
Query Neighborhood Hits	190	Target Neighborhood Hits	161	Shared Neighborhood Hits	25
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PNKP_MOUSE
θ value	5.27518 (rank : 174)	NC score	0.009330 (rank : 269)
Query Neighborhood Hits	190	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

VWF_MOUSE
θ value	5.27518 (rank : 175)	NC score	0.055236 (rank : 216)
Query Neighborhood Hits	190	Target Neighborhood Hits	381	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WISP1_HUMAN
θ value	5.27518 (rank : 176)	NC score	0.093499 (rank : 138)
Query Neighborhood Hits	190	Target Neighborhood Hits	121	Shared Neighborhood Hits	61
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

FINC_HUMAN
θ value	6.88961 (rank : 177)	NC score	0.002174 (rank : 277)
Query Neighborhood Hits	190	Target Neighborhood Hits	302	Shared Neighborhood Hits	8
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

GP143_MOUSE
θ value	6.88961 (rank : 178)	NC score	0.005843 (rank : 273)
Query Neighborhood Hits	190	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P70259, O89031	Gene names	Gpr143, Oa1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein homolog) (MOA1).

ITB6_MOUSE
θ value	6.88961 (rank : 179)	NC score	0.018888 (rank : 262)
Query Neighborhood Hits	190	Target Neighborhood Hits	341	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

KRA55_HUMAN
θ value	6.88961 (rank : 180)	NC score	0.022331 (rank : 260)
Query Neighborhood Hits	190	Target Neighborhood Hits	257	Shared Neighborhood Hits	28
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LYPD5_HUMAN
θ value	6.88961 (rank : 181)	NC score	0.005413 (rank : 274)
Query Neighborhood Hits	190	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UWN5, Q6PEX9, Q96DR2	Gene names	LYPD5
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 5 precursor.

RSPO1_HUMAN
θ value	6.88961 (rank : 182)	NC score	0.089381 (rank : 142)
Query Neighborhood Hits	190	Target Neighborhood Hits	101	Shared Neighborhood Hits	50
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO2_HUMAN
θ value	6.88961 (rank : 183)	NC score	0.049853 (rank : 235)
Query Neighborhood Hits	190	Target Neighborhood Hits	90	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

DLL3_MOUSE
θ value	8.99809 (rank : 184)	NC score	0.031925 (rank : 258)
Query Neighborhood Hits	190	Target Neighborhood Hits	399	Shared Neighborhood Hits	48
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

NOTC3_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.041229 (rank : 247)
Query Neighborhood Hits	190	Target Neighborhood Hits	1062	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PCSK5_MOUSE
θ value	8.99809 (rank : 186)	NC score	0.044541 (rank : 243)
Query Neighborhood Hits	190	Target Neighborhood Hits	613	Shared Neighborhood Hits	67
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

RHEB_HUMAN
θ value	8.99809 (rank : 187)	NC score	-0.003782 (rank : 281)
Query Neighborhood Hits	190	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q15382, Q99444	Gene names	RHEB, RHEB2
Domain Architecture
Description	GTP-binding protein Rheb (Ras homolog enriched in brain).

RHEB_MOUSE
θ value	8.99809 (rank : 188)	NC score	-0.003779 (rank : 280)
Query Neighborhood Hits	190	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q921J2	Gene names	Rheb
Domain Architecture
Description	GTP-binding protein Rheb (Ras homolog enriched in brain).

UFO_MOUSE
θ value	8.99809 (rank : 189)	NC score	-0.000557 (rank : 278)
Query Neighborhood Hits	190	Target Neighborhood Hits	988	Shared Neighborhood Hits	17
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

VMO1_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.007721 (rank : 270)
Query Neighborhood Hits	190	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SXG7	Gene names	Vmo1, Gm741
Domain Architecture	No domain graphic available
Description	Vitelline membrane outer layer protein 1 homolog precursor.

AD26A_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.064589 (rank : 191)
Query Neighborhood Hits	190	Target Neighborhood Hits	165	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA11_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.062886 (rank : 197)
Query Neighborhood Hits	190	Target Neighborhood Hits	259	Shared Neighborhood Hits	62
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.070068 (rank : 175)
Query Neighborhood Hits	190	Target Neighborhood Hits	263	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA12_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.090956 (rank : 139)
Query Neighborhood Hits	190	Target Neighborhood Hits	224	Shared Neighborhood Hits	48
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.089259 (rank : 143)
Query Neighborhood Hits	190	Target Neighborhood Hits	474	Shared Neighborhood Hits	51
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.087255 (rank : 146)
Query Neighborhood Hits	190	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.076841 (rank : 161)
Query Neighborhood Hits	190	Target Neighborhood Hits	324	Shared Neighborhood Hits	60
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.050308 (rank : 231)
Query Neighborhood Hits	190	Target Neighborhood Hits	223	Shared Neighborhood Hits	52
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.051108 (rank : 229)
Query Neighborhood Hits	190	Target Neighborhood Hits	201	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA19_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.096381 (rank : 135)
Query Neighborhood Hits	190	Target Neighborhood Hits	381	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.101991 (rank : 132)
Query Neighborhood Hits	190	Target Neighborhood Hits	315	Shared Neighborhood Hits	66
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA21_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.066441 (rank : 188)
Query Neighborhood Hits	190	Target Neighborhood Hits	181	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA21_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.072131 (rank : 170)
Query Neighborhood Hits	190	Target Neighborhood Hits	172	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.075710 (rank : 163)
Query Neighborhood Hits	190	Target Neighborhood Hits	211	Shared Neighborhood Hits	52
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.072642 (rank : 168)
Query Neighborhood Hits	190	Target Neighborhood Hits	225	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.069396 (rank : 176)
Query Neighborhood Hits	190	Target Neighborhood Hits	235	Shared Neighborhood Hits	58
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.070816 (rank : 174)
Query Neighborhood Hits	190	Target Neighborhood Hits	245	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.071687 (rank : 172)
Query Neighborhood Hits	190	Target Neighborhood Hits	230	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.066444 (rank : 187)
Query Neighborhood Hits	190	Target Neighborhood Hits	213	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.095005 (rank : 136)
Query Neighborhood Hits	190	Target Neighborhood Hits	244	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA28_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.097774 (rank : 134)
Query Neighborhood Hits	190	Target Neighborhood Hits	241	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA29_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.067285 (rank : 185)
Query Neighborhood Hits	190	Target Neighborhood Hits	247	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA32_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.051546 (rank : 226)
Query Neighborhood Hits	190	Target Neighborhood Hits	216	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.050166 (rank : 232)
Query Neighborhood Hits	190	Target Neighborhood Hits	219	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA33_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.093750 (rank : 137)
Query Neighborhood Hits	190	Target Neighborhood Hits	264	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.084232 (rank : 155)
Query Neighborhood Hits	190	Target Neighborhood Hits	231	Shared Neighborhood Hits	56
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.054837 (rank : 217)
Query Neighborhood Hits	190	Target Neighborhood Hits	209	Shared Neighborhood Hits	58
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.085984 (rank : 151)
Query Neighborhood Hits	190	Target Neighborhood Hits	221	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.086099 (rank : 150)
Query Neighborhood Hits	190	Target Neighborhood Hits	200	Shared Neighborhood Hits	52
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM8_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.104947 (rank : 129)
Query Neighborhood Hits	190	Target Neighborhood Hits	327	Shared Neighborhood Hits	63
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM9_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.084552 (rank : 154)
Query Neighborhood Hits	190	Target Neighborhood Hits	243	Shared Neighborhood Hits	60
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.090666 (rank : 140)
Query Neighborhood Hits	190	Target Neighborhood Hits	325	Shared Neighborhood Hits	62
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADEC1_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.090159 (rank : 141)
Query Neighborhood Hits	190	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.072125 (rank : 171)
Query Neighborhood Hits	190	Target Neighborhood Hits	85	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADM1A_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.071561 (rank : 173)
Query Neighborhood Hits	190	Target Neighborhood Hits	230	Shared Neighborhood Hits	56
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.074377 (rank : 166)
Query Neighborhood Hits	190	Target Neighborhood Hits	236	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

BMPER_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.056907 (rank : 211)
Query Neighborhood Hits	190	Target Neighborhood Hits	175	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.054519 (rank : 219)
Query Neighborhood Hits	190	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CD97_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.067792 (rank : 182)
Query Neighborhood Hits	190	Target Neighborhood Hits	353	Shared Neighborhood Hits	36
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.064843 (rank : 190)
Query Neighborhood Hits	190	Target Neighborhood Hits	295	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CO9_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.087941 (rank : 144)
Query Neighborhood Hits	190	Target Neighborhood Hits	147	Shared Neighborhood Hits	33
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

COMP_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.086380 (rank : 149)
Query Neighborhood Hits	190	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.086384 (rank : 148)
Query Neighborhood Hits	190	Target Neighborhood Hits	290	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CTGF_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.060400 (rank : 204)
Query Neighborhood Hits	190	Target Neighborhood Hits	128	Shared Neighborhood Hits	51
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.063532 (rank : 195)
Query Neighborhood Hits	190	Target Neighborhood Hits	124	Shared Neighborhood Hits	53
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

ELTD1_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.078067 (rank : 160)
Query Neighborhood Hits	190	Target Neighborhood Hits	269	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.072741 (rank : 167)
Query Neighborhood Hits	190	Target Neighborhood Hits	288	Shared Neighborhood Hits	35
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.068041 (rank : 181)
Query Neighborhood Hits	190	Target Neighborhood Hits	382	Shared Neighborhood Hits	44
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.069036 (rank : 177)
Query Neighborhood Hits	190	Target Neighborhood Hits	349	Shared Neighborhood Hits	40
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.064227 (rank : 192)
Query Neighborhood Hits	190	Target Neighborhood Hits	345	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.061290 (rank : 200)
Query Neighborhood Hits	190	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.067393 (rank : 183)
Query Neighborhood Hits	190	Target Neighborhood Hits	191	Shared Neighborhood Hits	21
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

GP110_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.065730 (rank : 189)
Query Neighborhood Hits	190	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP110_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.062269 (rank : 198)
Query Neighborhood Hits	190	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP111_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.053239 (rank : 221)
Query Neighborhood Hits	190	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

GP112_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.052963 (rank : 222)
Query Neighborhood Hits	190	Target Neighborhood Hits	441	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP113_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.074610 (rank : 165)
Query Neighborhood Hits	190	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP114_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.050106 (rank : 233)
Query Neighborhood Hits	190	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP115_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.060363 (rank : 205)
Query Neighborhood Hits	190	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GP115_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.059023 (rank : 207)
Query Neighborhood Hits	190	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP116_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.068619 (rank : 179)
Query Neighborhood Hits	190	Target Neighborhood Hits	167	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP128_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.061509 (rank : 199)
Query Neighborhood Hits	190	Target Neighborhood Hits	135	Shared Neighborhood Hits	13
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP128_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.051999 (rank : 225)
Query Neighborhood Hits	190	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.063640 (rank : 194)
Query Neighborhood Hits	190	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP144_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.055292 (rank : 215)
Query Neighborhood Hits	190	Target Neighborhood Hits	108	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GPR64_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.056130 (rank : 213)
Query Neighborhood Hits	190	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GPR64_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.054828 (rank : 218)
Query Neighborhood Hits	190	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR97_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.057185 (rank : 210)
Query Neighborhood Hits	190	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GPR97_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.059440 (rank : 206)
Query Neighborhood Hits	190	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

KR102_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.050070 (rank : 234)
Query Neighborhood Hits	190	Target Neighborhood Hits	264	Shared Neighborhood Hits	47
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.054020 (rank : 220)
Query Neighborhood Hits	190	Target Neighborhood Hits	313	Shared Neighborhood Hits	48
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR106_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.057249 (rank : 209)
Query Neighborhood Hits	190	Target Neighborhood Hits	347	Shared Neighborhood Hits	59
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.051385 (rank : 228)
Query Neighborhood Hits	190	Target Neighborhood Hits	330	Shared Neighborhood Hits	53
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

LPHN1_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.056853 (rank : 212)
Query Neighborhood Hits	190	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.056096 (rank : 214)
Query Neighborhood Hits	190	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.057946 (rank : 208)
Query Neighborhood Hits	190	Target Neighborhood Hits	139	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

NELL1_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.050675 (rank : 230)
Query Neighborhood Hits	190	Target Neighborhood Hits	451	Shared Neighborhood Hits	50
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NOV_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.067127 (rank : 186)
Query Neighborhood Hits	190	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.068298 (rank : 180)
Query Neighborhood Hits	190	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

ROBO4_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.052126 (rank : 224)
Query Neighborhood Hits	190	Target Neighborhood Hits	358	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

RSPO1_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.072528 (rank : 169)
Query Neighborhood Hits	190	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO3_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.068635 (rank : 178)
Query Neighborhood Hits	190	Target Neighborhood Hits	128	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.067376 (rank : 184)
Query Neighborhood Hits	190	Target Neighborhood Hits	120	Shared Neighborhood Hits	38
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.060776 (rank : 202)
Query Neighborhood Hits	190	Target Neighborhood Hits	110	Shared Neighborhood Hits	37
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.076651 (rank : 162)
Query Neighborhood Hits	190	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

TSP3_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.086649 (rank : 147)
Query Neighborhood Hits	190	Target Neighborhood Hits	250	Shared Neighborhood Hits	28
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.085423 (rank : 152)
Query Neighborhood Hits	190	Target Neighborhood Hits	247	Shared Neighborhood Hits	27
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.083357 (rank : 156)
Query Neighborhood Hits	190	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.082309 (rank : 157)
Query Neighborhood Hits	190	Target Neighborhood Hits	276	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

WISP3_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.063823 (rank : 193)
Query Neighborhood Hits	190	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ZAN_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.063438 (rank : 196)
Query Neighborhood Hits	190	Target Neighborhood Hits	808	Shared Neighborhood Hits	74
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

SEM5B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	190	Target Neighborhood Hits	190	Shared Neighborhood Hits	190
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5B_HUMAN
NC score	0.998299 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	190	Target Neighborhood Hits	178	Shared Neighborhood Hits	163
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5A_MOUSE
NC score	0.994611 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	190	Target Neighborhood Hits	162	Shared Neighborhood Hits	141
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_HUMAN
NC score	0.994034 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	190	Target Neighborhood Hits	177	Shared Neighborhood Hits	146
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM4A_HUMAN
NC score	0.803379 (rank : 5)	θ value	1.5555e-68 (rank : 19)
Query Neighborhood Hits	190	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4C_HUMAN
NC score	0.802102 (rank : 6)	θ value	6.31527e-70 (rank : 17)
Query Neighborhood Hits	190	Target Neighborhood Hits	84	Shared Neighborhood Hits	54
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SEM6C_HUMAN
NC score	0.802093 (rank : 7)	θ value	3.12697e-77 (rank : 11)
Query Neighborhood Hits	190	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6B_HUMAN
NC score	0.801643 (rank : 8)	θ value	9.7205e-79 (rank : 8)
Query Neighborhood Hits	190	Target Neighborhood Hits	187	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SEM4A_MOUSE
NC score	0.801410 (rank : 9)	θ value	1.77973e-64 (rank : 32)
Query Neighborhood Hits	190	Target Neighborhood Hits	65	Shared Neighborhood Hits	53
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM6A_HUMAN
NC score	0.801165 (rank : 10)	θ value	8.22888e-78 (rank : 9)
Query Neighborhood Hits	190	Target Neighborhood Hits	96	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM6A_MOUSE
NC score	0.801163 (rank : 11)	θ value	5.69867e-79 (rank : 7)
Query Neighborhood Hits	190	Target Neighborhood Hits	96	Shared Neighborhood Hits	53
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SEM4B_MOUSE
NC score	0.801145 (rank : 12)	θ value	2.74572e-65 (rank : 31)
Query Neighborhood Hits	190	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q62179, Q4PKI6, Q69ZB7	Gene names	Sema4b, Kiaa1745, Semac, SemC
Domain Architecture	No domain graphic available
Description	Semaphorin-4B precursor (Semaphorin C) (Sema C).

SEM4B_HUMAN
NC score	0.800516 (rank : 13)	θ value	6.76295e-64 (rank : 33)
Query Neighborhood Hits	190	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NPR2, Q6UXE3, Q8WVP9, Q96FK5, Q9C0B8, Q9H691, Q9NPM8, Q9NPN0	Gene names	SEMA4B, KIAA1745
Domain Architecture
Description	Semaphorin-4B precursor.

SEM6D_MOUSE
NC score	0.800108 (rank : 14)	θ value	8.20983e-86 (rank : 5)
Query Neighborhood Hits	190	Target Neighborhood Hits	161	Shared Neighborhood Hits	53
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM4C_MOUSE
NC score	0.799742 (rank : 15)	θ value	5.34618e-69 (rank : 18)
Query Neighborhood Hits	190	Target Neighborhood Hits	77	Shared Neighborhood Hits	54
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM6D_HUMAN
NC score	0.799368 (rank : 16)	θ value	5.32145e-85 (rank : 6)
Query Neighborhood Hits	190	Target Neighborhood Hits	169	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6B_MOUSE
NC score	0.798494 (rank : 17)	θ value	1.40363e-77 (rank : 10)
Query Neighborhood Hits	190	Target Neighborhood Hits	200	Shared Neighborhood Hits	53
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SEM3F_HUMAN
NC score	0.795130 (rank : 18)	θ value	2.65329e-68 (rank : 20)
Query Neighborhood Hits	190	Target Neighborhood Hits	100	Shared Neighborhood Hits	61
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEM3B_HUMAN
NC score	0.794632 (rank : 19)	θ value	1.7756e-72 (rank : 16)
Query Neighborhood Hits	190	Target Neighborhood Hits	76	Shared Neighborhood Hits	54
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

SEM3C_MOUSE
NC score	0.794385 (rank : 20)	θ value	2.4834e-66 (rank : 27)
Query Neighborhood Hits	190	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3C_HUMAN
NC score	0.794299 (rank : 21)	θ value	1.2325e-65 (rank : 29)
Query Neighborhood Hits	190	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM4D_MOUSE
NC score	0.793679 (rank : 22)	θ value	1.71981e-67 (rank : 24)
Query Neighborhood Hits	190	Target Neighborhood Hits	143	Shared Neighborhood Hits	54
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SEM4F_MOUSE
NC score	0.793617 (rank : 23)	θ value	7.49467e-55 (rank : 34)
Query Neighborhood Hits	190	Target Neighborhood Hits	59	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

SEM3F_MOUSE
NC score	0.793432 (rank : 24)	θ value	2.65329e-68 (rank : 21)
Query Neighborhood Hits	190	Target Neighborhood Hits	86	Shared Neighborhood Hits	55
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEM3B_MOUSE
NC score	0.793214 (rank : 25)	θ value	1.45591e-66 (rank : 26)
Query Neighborhood Hits	190	Target Neighborhood Hits	75	Shared Neighborhood Hits	53
SwissProt Accessions	Q62177	Gene names	Sema3b, Sema, Semaa
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin A) (Sema A).

SEM4D_HUMAN
NC score	0.793176 (rank : 26)	θ value	1.11475e-66 (rank : 25)
Query Neighborhood Hits	190	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

SEM4F_HUMAN
NC score	0.792041 (rank : 27)	θ value	4.11246e-53 (rank : 35)
Query Neighborhood Hits	190	Target Neighborhood Hits	57	Shared Neighborhood Hits	54
SwissProt Accessions	O95754, Q9NS35	Gene names	SEMA4F, SEMAM, SEMAW
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W) (Semaphorin M) (Sema M).

SEM3A_HUMAN
NC score	0.790432 (rank : 28)	θ value	7.70199e-76 (rank : 14)
Query Neighborhood Hits	190	Target Neighborhood Hits	78	Shared Neighborhood Hits	54
SwissProt Accessions	Q14563	Gene names	SEMA3A
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III).

SEM3A_MOUSE
NC score	0.789951 (rank : 29)	θ value	5.8972e-76 (rank : 13)
Query Neighborhood Hits	190	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	O08665, Q5BL08, Q62180, Q62215	Gene names	Sema3a, Semad, SemD
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III) (Semaphorin D) (Sema D).

SEM3E_HUMAN
NC score	0.789412 (rank : 30)	θ value	7.71989e-68 (rank : 22)
Query Neighborhood Hits	190	Target Neighborhood Hits	73	Shared Neighborhood Hits	53
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

SEM4G_MOUSE
NC score	0.789214 (rank : 31)	θ value	3.2585e-50 (rank : 37)
Query Neighborhood Hits	190	Target Neighborhood Hits	99	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SEM4G_HUMAN
NC score	0.788892 (rank : 32)	θ value	6.56568e-51 (rank : 36)
Query Neighborhood Hits	190	Target Neighborhood Hits	88	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NTN9, Q9HCF3	Gene names	SEMA4G, KIAA1619
Domain Architecture
Description	Semaphorin-4G precursor.

SEM3E_MOUSE
NC score	0.788713 (rank : 33)	θ value	1.71981e-67 (rank : 23)
Query Neighborhood Hits	190	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM6C_MOUSE
NC score	0.787576 (rank : 34)	θ value	4.51533e-76 (rank : 12)
Query Neighborhood Hits	190	Target Neighborhood Hits	352	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM3D_HUMAN
NC score	0.786854 (rank : 35)	θ value	7.2256e-66 (rank : 28)
Query Neighborhood Hits	190	Target Neighborhood Hits	104	Shared Neighborhood Hits	53
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

SEM3D_MOUSE
NC score	0.785423 (rank : 36)	θ value	1.6097e-65 (rank : 30)
Query Neighborhood Hits	190	Target Neighborhood Hits	97	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

SEM7A_MOUSE
NC score	0.771057 (rank : 37)	θ value	1.79631e-32 (rank : 45)
Query Neighborhood Hits	190	Target Neighborhood Hits	64	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QUR8, O88371	Gene names	Sema7a, Cd108, Semal, Semk1
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (CD108 antigen) (CDw108).

SEM7A_HUMAN
NC score	0.769661 (rank : 38)	θ value	3.74554e-30 (rank : 50)
Query Neighborhood Hits	190	Target Neighborhood Hits	67	Shared Neighborhood Hits	53
SwissProt Accessions	O75326	Gene names	SEMA7A, CD108, SEMAL
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (John-Milton-Hargen human blood group Ag) (JMH blood group antigen) (CD108 antigen) (CDw108).

PROP_HUMAN
NC score	0.629151 (rank : 39)	θ value	1.67352e-46 (rank : 40)
Query Neighborhood Hits	190	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
NC score	0.627233 (rank : 40)	θ value	7.51208e-47 (rank : 39)
Query Neighborhood Hits	190	Target Neighborhood Hits	165	Shared Neighborhood Hits	93
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SPON1_MOUSE
NC score	0.530205 (rank : 41)	θ value	2.87452e-22 (rank : 60)
Query Neighborhood Hits	190	Target Neighborhood Hits	123	Shared Neighborhood Hits	90
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
NC score	0.527660 (rank : 42)	θ value	5.42112e-21 (rank : 61)
Query Neighborhood Hits	190	Target Neighborhood Hits	117	Shared Neighborhood Hits	89
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

UNC5A_MOUSE
NC score	0.486111 (rank : 43)	θ value	5.79196e-23 (rank : 55)
Query Neighborhood Hits	190	Target Neighborhood Hits	203	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_MOUSE
NC score	0.484328 (rank : 44)	θ value	7.56453e-23 (rank : 57)
Query Neighborhood Hits	190	Target Neighborhood Hits	226	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
NC score	0.483755 (rank : 45)	θ value	9.87957e-23 (rank : 58)
Query Neighborhood Hits	190	Target Neighborhood Hits	225	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5C_MOUSE
NC score	0.471207 (rank : 46)	θ value	5.79196e-23 (rank : 56)
Query Neighborhood Hits	190	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.470661 (rank : 47)	θ value	9.87957e-23 (rank : 59)
Query Neighborhood Hits	190	Target Neighborhood Hits	226	Shared Neighborhood Hits	81
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5D_HUMAN
NC score	0.468587 (rank : 48)	θ value	3.39556e-23 (rank : 53)
Query Neighborhood Hits	190	Target Neighborhood Hits	267	Shared Neighborhood Hits	84
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
NC score	0.466800 (rank : 49)	θ value	4.43474e-23 (rank : 54)
Query Neighborhood Hits	190	Target Neighborhood Hits	268	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

BAI1_MOUSE
NC score	0.463707 (rank : 50)	θ value	2.34062e-40 (rank : 42)
Query Neighborhood Hits	190	Target Neighborhood Hits	340	Shared Neighborhood Hits	95
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI3_MOUSE
NC score	0.463547 (rank : 51)	θ value	4.14116e-29 (rank : 52)
Query Neighborhood Hits	190	Target Neighborhood Hits	250	Shared Neighborhood Hits	93
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI1_HUMAN
NC score	0.462638 (rank : 52)	θ value	8.04462e-41 (rank : 41)
Query Neighborhood Hits	190	Target Neighborhood Hits	375	Shared Neighborhood Hits	96
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI3_HUMAN
NC score	0.460434 (rank : 53)	θ value	1.08979e-29 (rank : 51)
Query Neighborhood Hits	190	Target Neighborhood Hits	246	Shared Neighborhood Hits	91
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI2_HUMAN
NC score	0.457647 (rank : 54)	θ value	3.27365e-34 (rank : 44)
Query Neighborhood Hits	190	Target Neighborhood Hits	332	Shared Neighborhood Hits	95
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
NC score	0.457027 (rank : 55)	θ value	1.46948e-34 (rank : 43)
Query Neighborhood Hits	190	Target Neighborhood Hits	323	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ATL2_HUMAN
NC score	0.452128 (rank : 56)	θ value	8.97725e-08 (rank : 103)
Query Neighborhood Hits	190	Target Neighborhood Hits	125	Shared Neighborhood Hits	86
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
NC score	0.450714 (rank : 57)	θ value	5.81887e-07 (rank : 114)
Query Neighborhood Hits	190	Target Neighborhood Hits	137	Shared Neighborhood Hits	85
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

TSP2_MOUSE
NC score	0.444429 (rank : 58)	θ value	1.98606e-31 (rank : 48)
Query Neighborhood Hits	190	Target Neighborhood Hits	352	Shared Neighborhood Hits	113
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATS13_HUMAN
NC score	0.444041 (rank : 59)	θ value	1.2105e-12 (rank : 77)
Query Neighborhood Hits	190	Target Neighborhood Hits	238	Shared Neighborhood Hits	88
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

TSP2_HUMAN
NC score	0.441720 (rank : 60)	θ value	2.19584e-30 (rank : 49)
Query Neighborhood Hits	190	Target Neighborhood Hits	359	Shared Neighborhood Hits	115
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATS13_MOUSE
NC score	0.438923 (rank : 61)	θ value	1.133e-10 (rank : 93)
Query Neighborhood Hits	190	Target Neighborhood Hits	227	Shared Neighborhood Hits	87
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS9_HUMAN
NC score	0.438574 (rank : 62)	θ value	4.74913e-17 (rank : 62)
Query Neighborhood Hits	190	Target Neighborhood Hits	219	Shared Neighborhood Hits	99
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

TSP1_HUMAN
NC score	0.435480 (rank : 63)	θ value	1.16434e-31 (rank : 47)
Query Neighborhood Hits	190	Target Neighborhood Hits	389	Shared Neighborhood Hits	117
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
NC score	0.435277 (rank : 64)	θ value	8.91499e-32 (rank : 46)
Query Neighborhood Hits	190	Target Neighborhood Hits	396	Shared Neighborhood Hits	117
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

ATS18_MOUSE
NC score	0.434099 (rank : 65)	θ value	4.44505e-15 (rank : 64)
Query Neighborhood Hits	190	Target Neighborhood Hits	163	Shared Neighborhood Hits	88
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS20_MOUSE
NC score	0.432065 (rank : 66)	θ value	1.29331e-14 (rank : 66)
Query Neighborhood Hits	190	Target Neighborhood Hits	225	Shared Neighborhood Hits	95
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS8_MOUSE
NC score	0.431213 (rank : 67)	θ value	5.43371e-13 (rank : 73)
Query Neighborhood Hits	190	Target Neighborhood Hits	139	Shared Neighborhood Hits	84
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS18_HUMAN
NC score	0.429740 (rank : 68)	θ value	9.90251e-15 (rank : 65)
Query Neighborhood Hits	190	Target Neighborhood Hits	169	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_MOUSE
NC score	0.429378 (rank : 69)	θ value	2.43908e-13 (rank : 71)
Query Neighborhood Hits	190	Target Neighborhood Hits	179	Shared Neighborhood Hits	87
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_HUMAN
NC score	0.428459 (rank : 70)	θ value	4.91457e-14 (rank : 69)
Query Neighborhood Hits	190	Target Neighborhood Hits	208	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS17_HUMAN
NC score	0.427975 (rank : 71)	θ value	7.09661e-13 (rank : 74)
Query Neighborhood Hits	190	Target Neighborhood Hits	194	Shared Neighborhood Hits	92
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS8_HUMAN
NC score	0.427104 (rank : 72)	θ value	2.88119e-14 (rank : 67)
Query Neighborhood Hits	190	Target Neighborhood Hits	145	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS4_HUMAN
NC score	0.426097 (rank : 73)	θ value	1.58096e-12 (rank : 80)
Query Neighborhood Hits	190	Target Neighborhood Hits	138	Shared Neighborhood Hits	80
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS20_HUMAN
NC score	0.425861 (rank : 74)	θ value	2.35696e-16 (rank : 63)
Query Neighborhood Hits	190	Target Neighborhood Hits	192	Shared Neighborhood Hits	94
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATL5_HUMAN
NC score	0.425838 (rank : 75)	θ value	9.92553e-07 (rank : 117)
Query Neighborhood Hits	190	Target Neighborhood Hits	103	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATS4_MOUSE
NC score	0.425019 (rank : 76)	θ value	2.69671e-12 (rank : 82)
Query Neighborhood Hits	190	Target Neighborhood Hits	145	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS2_HUMAN
NC score	0.423327 (rank : 77)	θ value	2.98157e-11 (rank : 90)
Query Neighborhood Hits	190	Target Neighborhood Hits	179	Shared Neighborhood Hits	82
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
NC score	0.422772 (rank : 78)	θ value	1.2105e-12 (rank : 78)
Query Neighborhood Hits	190	Target Neighborhood Hits	179	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS14_HUMAN
NC score	0.422751 (rank : 79)	θ value	3.18553e-13 (rank : 72)
Query Neighborhood Hits	190	Target Neighborhood Hits	382	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATL1_HUMAN
NC score	0.420190 (rank : 80)	θ value	1.38499e-08 (rank : 99)
Query Neighborhood Hits	190	Target Neighborhood Hits	93	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
NC score	0.419181 (rank : 81)	θ value	5.26297e-08 (rank : 102)
Query Neighborhood Hits	190	Target Neighborhood Hits	80	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATS1_MOUSE
NC score	0.418262 (rank : 82)	θ value	1.02475e-11 (rank : 87)
Query Neighborhood Hits	190	Target Neighborhood Hits	158	Shared Neighborhood Hits	87
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS15_HUMAN
NC score	0.418240 (rank : 83)	θ value	1.42992e-13 (rank : 70)
Query Neighborhood Hits	190	Target Neighborhood Hits	151	Shared Neighborhood Hits	85
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS12_MOUSE
NC score	0.417518 (rank : 84)	θ value	2.0648e-12 (rank : 81)
Query Neighborhood Hits	190	Target Neighborhood Hits	220	Shared Neighborhood Hits	89
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS1_HUMAN
NC score	0.417354 (rank : 85)	θ value	7.84624e-12 (rank : 86)
Query Neighborhood Hits	190	Target Neighborhood Hits	159	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS12_HUMAN
NC score	0.416780 (rank : 86)	θ value	1.58096e-12 (rank : 79)
Query Neighborhood Hits	190	Target Neighborhood Hits	251	Shared Neighborhood Hits	88
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS6_HUMAN
NC score	0.414929 (rank : 87)	θ value	1.02475e-11 (rank : 88)
Query Neighborhood Hits	190	Target Neighborhood Hits	141	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS3_HUMAN
NC score	0.410817 (rank : 88)	θ value	4.30538e-10 (rank : 95)
Query Neighborhood Hits	190	Target Neighborhood Hits	179	Shared Neighborhood Hits	87
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS7_HUMAN
NC score	0.410225 (rank : 89)	θ value	4.59992e-12 (rank : 84)
Query Neighborhood Hits	190	Target Neighborhood Hits	169	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS5_MOUSE
NC score	0.407675 (rank : 90)	θ value	2.69671e-12 (rank : 83)
Query Neighborhood Hits	190	Target Neighborhood Hits	147	Shared Neighborhood Hits	81
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS19_MOUSE
NC score	0.404736 (rank : 91)	θ value	2.28291e-11 (rank : 89)
Query Neighborhood Hits	190	Target Neighborhood Hits	188	Shared Neighborhood Hits	82
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS5_HUMAN
NC score	0.403199 (rank : 92)	θ value	6.00763e-12 (rank : 85)
Query Neighborhood Hits	190	Target Neighborhood Hits	141	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS19_HUMAN
NC score	0.398997 (rank : 93)	θ value	3.89403e-11 (rank : 91)
Query Neighborhood Hits	190	Target Neighborhood Hits	203	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

SSPO_MOUSE
NC score	0.393289 (rank : 94)	θ value	4.70527e-49 (rank : 38)
Query Neighborhood Hits	190	Target Neighborhood Hits	800	Shared Neighborhood Hits	130
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

THSD1_HUMAN
NC score	0.391915 (rank : 95)	θ value	2.61198e-07 (rank : 108)
Query Neighborhood Hits	190	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ATL3_HUMAN
NC score	0.383924 (rank : 96)	θ value	2.52405e-10 (rank : 94)
Query Neighborhood Hits	190	Target Neighborhood Hits	414	Shared Neighborhood Hits	90
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

UNC5A_HUMAN
NC score	0.379443 (rank : 97)	θ value	4.45536e-07 (rank : 113)
Query Neighborhood Hits	190	Target Neighborhood Hits	198	Shared Neighborhood Hits	74
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

PLXB2_HUMAN
NC score	0.372307 (rank : 98)	θ value	1.63604e-09 (rank : 97)
Query Neighborhood Hits	190	Target Neighborhood Hits	94	Shared Neighborhood Hits	55
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

THSD1_MOUSE
NC score	0.370426 (rank : 99)	θ value	0.000158464 (rank : 121)
Query Neighborhood Hits	190	Target Neighborhood Hits	153	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CO8B_MOUSE
NC score	0.364147 (rank : 100)	θ value	3.41135e-07 (rank : 110)
Query Neighborhood Hits	190	Target Neighborhood Hits	224	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO6_HUMAN
NC score	0.356149 (rank : 101)	θ value	1.80886e-08 (rank : 100)
Query Neighborhood Hits	190	Target Neighborhood Hits	331	Shared Neighborhood Hits	103
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

PLXA4_HUMAN
NC score	0.354943 (rank : 102)	θ value	2.88119e-14 (rank : 68)
Query Neighborhood Hits	190	Target Neighborhood Hits	106	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_MOUSE
NC score	0.353172 (rank : 103)	θ value	7.09661e-13 (rank : 75)
Query Neighborhood Hits	190	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

CO8A_HUMAN
NC score	0.349765 (rank : 104)	θ value	8.97725e-08 (rank : 104)
Query Neighborhood Hits	190	Target Neighborhood Hits	200	Shared Neighborhood Hits	86
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
NC score	0.346240 (rank : 105)	θ value	1.53129e-07 (rank : 105)
Query Neighborhood Hits	190	Target Neighborhood Hits	199	Shared Neighborhood Hits	84
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8A_MOUSE
NC score	0.345894 (rank : 106)	θ value	3.41135e-07 (rank : 109)
Query Neighborhood Hits	190	Target Neighborhood Hits	182	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

PLXC1_MOUSE
NC score	0.343358 (rank : 107)	θ value	0.000602161 (rank : 122)
Query Neighborhood Hits	190	Target Neighborhood Hits	84	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QZC2, Q8CGW1	Gene names	Plxnc1, Vespr
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXA2_HUMAN
NC score	0.337561 (rank : 108)	θ value	7.34386e-10 (rank : 96)
Query Neighborhood Hits	190	Target Neighborhood Hits	100	Shared Neighborhood Hits	56
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

PLXC1_HUMAN
NC score	0.334774 (rank : 109)	θ value	0.00102713 (rank : 123)
Query Neighborhood Hits	190	Target Neighborhood Hits	94	Shared Neighborhood Hits	55
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXA2_MOUSE
NC score	0.333994 (rank : 110)	θ value	1.99992e-07 (rank : 106)
Query Neighborhood Hits	190	Target Neighborhood Hits	97	Shared Neighborhood Hits	55
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

CILP2_HUMAN
NC score	0.331282 (rank : 111)	θ value	3.08544e-08 (rank : 101)
Query Neighborhood Hits	190	Target Neighborhood Hits	307	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

PLXA1_MOUSE
NC score	0.328136 (rank : 112)	θ value	4.45536e-07 (rank : 112)
Query Neighborhood Hits	190	Target Neighborhood Hits	107	Shared Neighborhood Hits	55
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

CO7_HUMAN
NC score	0.325604 (rank : 113)	θ value	5.81887e-07 (rank : 115)
Query Neighborhood Hits	190	Target Neighborhood Hits	278	Shared Neighborhood Hits	89
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

PLXB1_HUMAN
NC score	0.325465 (rank : 114)	θ value	3.64472e-09 (rank : 98)
Query Neighborhood Hits	190	Target Neighborhood Hits	360	Shared Neighborhood Hits	60
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PLXB1_MOUSE
NC score	0.324120 (rank : 115)	θ value	3.41135e-07 (rank : 111)
Query Neighborhood Hits	190	Target Neighborhood Hits	259	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PLXA1_HUMAN
NC score	0.322823 (rank : 116)	θ value	5.81887e-07 (rank : 116)
Query Neighborhood Hits	190	Target Neighborhood Hits	108	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

PLXA3_HUMAN
NC score	0.320506 (rank : 117)	θ value	4.92598e-06 (rank : 118)
Query Neighborhood Hits	190	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	P51805	Gene names	PLXNA3, PLXN4, SEX
Domain Architecture
Description	Plexin-A3 precursor (Plexin-4) (Semaphorin receptor SEX).

PLXB3_MOUSE
NC score	0.316219 (rank : 118)	θ value	7.09661e-13 (rank : 76)
Query Neighborhood Hits	190	Target Neighborhood Hits	94	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

PLXB3_HUMAN
NC score	0.310809 (rank : 119)	θ value	6.64225e-11 (rank : 92)
Query Neighborhood Hits	190	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

CI094_HUMAN
NC score	0.309146 (rank : 120)	θ value	6.43352e-06 (rank : 119)
Query Neighborhood Hits	190	Target Neighborhood Hits	310	Shared Neighborhood Hits	72
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

PLXD1_HUMAN
NC score	0.298640 (rank : 121)	θ value	1.99992e-07 (rank : 107)
Query Neighborhood Hits	190	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

HMCN1_HUMAN
NC score	0.283896 (rank : 122)	θ value	2.47765e-74 (rank : 15)
Query Neighborhood Hits	190	Target Neighborhood Hits	983	Shared Neighborhood Hits	127
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CILP1_MOUSE
NC score	0.267960 (rank : 123)	θ value	9.29e-05 (rank : 120)
Query Neighborhood Hits	190	Target Neighborhood Hits	282	Shared Neighborhood Hits	85
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_HUMAN
NC score	0.253992 (rank : 124)	θ value	0.0193708 (rank : 125)
Query Neighborhood Hits	190	Target Neighborhood Hits	266	Shared Neighborhood Hits	82
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

SPON2_HUMAN
NC score	0.141730 (rank : 125)	θ value	1.06291 (rank : 147)
Query Neighborhood Hits	190	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON2_MOUSE
NC score	0.113470 (rank : 126)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	190	Target Neighborhood Hits	42	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

WISP2_HUMAN
NC score	0.111617 (rank : 127)	θ value	0.0961366 (rank : 131)
Query Neighborhood Hits	190	Target Neighborhood Hits	126	Shared Neighborhood Hits	60
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
NC score	0.108873 (rank : 128)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	190	Target Neighborhood Hits	129	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ADAM8_HUMAN
NC score	0.104947 (rank : 129)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	190	Target Neighborhood Hits	327	Shared Neighborhood Hits	63
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
NC score	0.104566 (rank : 130)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	190	Target Neighborhood Hits	326	Shared Neighborhood Hits	67
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CO9_MOUSE
NC score	0.104025 (rank : 131)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	190	Target Neighborhood Hits	153	Shared Neighborhood Hits	38
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

ADA19_MOUSE
NC score	0.101991 (rank : 132)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	190	Target Neighborhood Hits	315	Shared Neighborhood Hits	66
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

WISP1_MOUSE
NC score	0.098045 (rank : 133)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	190	Target Neighborhood Hits	123	Shared Neighborhood Hits	57
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ADA28_MOUSE
NC score	0.097774 (rank : 134)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	190	Target Neighborhood Hits	241	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA19_HUMAN
NC score	0.096381 (rank : 135)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	190	Target Neighborhood Hits	381	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA28_HUMAN
NC score	0.095005 (rank : 136)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	190	Target Neighborhood Hits	244	Shared Neighborhood Hits	54
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA33_HUMAN
NC score	0.093750 (rank : 137)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	190	Target Neighborhood Hits	264	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

WISP1_HUMAN
NC score	0.093499 (rank : 138)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	190	Target Neighborhood Hits	121	Shared Neighborhood Hits	61
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

ADA12_HUMAN
NC score	0.090956 (rank : 139)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	190	Target Neighborhood Hits	224	Shared Neighborhood Hits	48
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM9_MOUSE
NC score	0.090666 (rank : 140)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	190	Target Neighborhood Hits	325	Shared Neighborhood Hits	62
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADEC1_HUMAN
NC score	0.090159 (rank : 141)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	190	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

RSPO1_HUMAN
NC score	0.089381 (rank : 142)	θ value	6.88961 (rank : 182)
Query Neighborhood Hits	190	Target Neighborhood Hits	101	Shared Neighborhood Hits	50
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

ADA12_MOUSE
NC score	0.089259 (rank : 143)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	190	Target Neighborhood Hits	474	Shared Neighborhood Hits	51
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CO9_HUMAN
NC score	0.087941 (rank : 144)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	190	Target Neighborhood Hits	147	Shared Neighborhood Hits	33
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CYR61_HUMAN
NC score	0.087264 (rank : 145)	θ value	0.47712 (rank : 142)
Query Neighborhood Hits	190	Target Neighborhood Hits	159	Shared Neighborhood Hits	66
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

ADA15_HUMAN
NC score	0.087255 (rank : 146)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	190	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

TSP3_HUMAN
NC score	0.086649 (rank : 147)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	190	Target Neighborhood Hits	250	Shared Neighborhood Hits	28
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

COMP_MOUSE
NC score	0.086384 (rank : 148)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	190	Target Neighborhood Hits	290	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_HUMAN
NC score	0.086380 (rank : 149)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	190	Target Neighborhood Hits	258	Shared Neighborhood Hits	36
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

ADAM7_MOUSE
NC score	0.086099 (rank : 150)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	190	Target Neighborhood Hits	200	Shared Neighborhood Hits	52
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM7_HUMAN
NC score	0.085984 (rank : 151)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	190	Target Neighborhood Hits	221	Shared Neighborhood Hits	57
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

TSP3_MOUSE
NC score	0.085423 (rank : 152)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	190	Target Neighborhood Hits	247	Shared Neighborhood Hits	27
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

FRAS1_MOUSE
NC score	0.084628 (rank : 153)	θ value	0.0252991 (rank : 126)
Query Neighborhood Hits	190	Target Neighborhood Hits	747	Shared Neighborhood Hits	93
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ADAM9_HUMAN
NC score	0.084552 (rank : 154)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	190	Target Neighborhood Hits	243	Shared Neighborhood Hits	60
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADA33_MOUSE
NC score	0.084232 (rank : 155)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	190	Target Neighborhood Hits	231	Shared Neighborhood Hits	56
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

TSP4_HUMAN
NC score	0.083357 (rank : 156)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	190	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
NC score	0.082309 (rank : 157)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	190	Target Neighborhood Hits	276	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

FRAS1_HUMAN
NC score	0.079199 (rank : 158)	θ value	0.21417 (rank : 137)
Query Neighborhood Hits	190	Target Neighborhood Hits	759	Shared Neighborhood Hits	84
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CYR61_MOUSE
NC score	0.079094 (rank : 159)	θ value	0.21417 (rank : 136)
Query Neighborhood Hits	190	Target Neighborhood Hits	156	Shared Neighborhood Hits	62
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

ELTD1_HUMAN
NC score	0.078067 (rank : 160)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	190	Target Neighborhood Hits	269	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ADA15_MOUSE
NC score	0.076841 (rank : 161)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	190	Target Neighborhood Hits	324	Shared Neighborhood Hits	60
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

RSPO4_MOUSE
NC score	0.076651 (rank : 162)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	190	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

ADA22_HUMAN
NC score	0.075710 (rank : 163)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	190	Target Neighborhood Hits	211	Shared Neighborhood Hits	52
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

VWF_HUMAN
NC score	0.075464 (rank : 164)	θ value	0.00102713 (rank : 124)
Query Neighborhood Hits	190	Target Neighborhood Hits	396	Shared Neighborhood Hits	58
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

GP113_HUMAN
NC score	0.074610 (rank : 165)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	190	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

ADM1B_MOUSE
NC score	0.074377 (rank : 166)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	190	Target Neighborhood Hits	236	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ELTD1_MOUSE
NC score	0.072741 (rank : 167)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	190	Target Neighborhood Hits	288	Shared Neighborhood Hits	35
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ADA22_MOUSE
NC score	0.072642 (rank : 168)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	190	Target Neighborhood Hits	225	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

RSPO1_MOUSE
NC score	0.072528 (rank : 169)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	190	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

ADA21_MOUSE
NC score	0.072131 (rank : 170)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	190	Target Neighborhood Hits	172	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADEC1_MOUSE
NC score	0.072125 (rank : 171)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	190	Target Neighborhood Hits	85	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA24_MOUSE
NC score	0.071687 (rank : 172)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	190	Target Neighborhood Hits	230	Shared Neighborhood Hits	58
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADM1A_MOUSE
NC score	0.071561 (rank : 173)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	190	Target Neighborhood Hits	230	Shared Neighborhood Hits	56
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA23_MOUSE
NC score	0.070816 (rank : 174)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	190	Target Neighborhood Hits	245	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA11_MOUSE
NC score	0.070068 (rank : 175)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	190	Target Neighborhood Hits	263	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA23_HUMAN
NC score	0.069396 (rank : 176)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	190	Target Neighborhood Hits	235	Shared Neighborhood Hits	58
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

EMR1_MOUSE
NC score	0.069036 (rank : 177)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	190	Target Neighborhood Hits	349	Shared Neighborhood Hits	40
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

RSPO3_HUMAN
NC score	0.068635 (rank : 178)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	190	Target Neighborhood Hits	128	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

GP116_HUMAN
NC score	0.068619 (rank : 179)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	190	Target Neighborhood Hits	167	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

NOV_MOUSE
NC score	0.068298 (rank : 180)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	190	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

EMR1_HUMAN
NC score	0.068041 (rank : 181)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	190	Target Neighborhood Hits	382	Shared Neighborhood Hits	44
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

CD97_HUMAN
NC score	0.067792 (rank : 182)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	190	Target Neighborhood Hits	353	Shared Neighborhood Hits	36
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR4_MOUSE
NC score	0.067393 (rank : 183)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	190	Target Neighborhood Hits	191	Shared Neighborhood Hits	21
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

RSPO3_MOUSE
NC score	0.067376 (rank : 184)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	190	Target Neighborhood Hits	120	Shared Neighborhood Hits	38
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

ADA29_HUMAN
NC score	0.067285 (rank : 185)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	190	Target Neighborhood Hits	247	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

NOV_HUMAN
NC score	0.067127 (rank : 186)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	190	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

ADA25_MOUSE
NC score	0.066444 (rank : 187)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	190	Target Neighborhood Hits	213	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA21_HUMAN
NC score	0.066441 (rank : 188)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	190	Target Neighborhood Hits	181	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

GP110_HUMAN
NC score	0.065730 (rank : 189)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	190	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

CD97_MOUSE
NC score	0.064843 (rank : 190)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	190	Target Neighborhood Hits	295	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

AD26A_MOUSE
NC score	0.064589 (rank : 191)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	190	Target Neighborhood Hits	165	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

EMR2_HUMAN
NC score	0.064227 (rank : 192)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	190	Target Neighborhood Hits	345	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

WISP3_HUMAN
NC score	0.063823 (rank : 193)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	190	Target Neighborhood Hits	87	Shared Neighborhood Hits	43
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

GP133_HUMAN
NC score	0.063640 (rank : 194)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	190	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

CTGF_MOUSE
NC score	0.063532 (rank : 195)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	190	Target Neighborhood Hits	124	Shared Neighborhood Hits	53
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

ZAN_MOUSE
NC score	0.063438 (rank : 196)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	190	Target Neighborhood Hits	808	Shared Neighborhood Hits	74
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ADA11_HUMAN
NC score	0.062886 (rank : 197)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	190	Target Neighborhood Hits	259	Shared Neighborhood Hits	62
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

GP110_MOUSE
NC score	0.062269 (rank : 198)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	190	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP128_HUMAN
NC score	0.061509 (rank : 199)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	190	Target Neighborhood Hits	135	Shared Neighborhood Hits	13
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

EMR3_HUMAN
NC score	0.061290 (rank : 200)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	190	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

CRIM1_HUMAN
NC score	0.061100 (rank : 201)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	190	Target Neighborhood Hits	362	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

RSPO4_HUMAN
NC score	0.060776 (rank : 202)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	190	Target Neighborhood Hits	110	Shared Neighborhood Hits	37
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

KRA51_HUMAN
NC score	0.060516 (rank : 203)	θ value	0.62314 (rank : 144)
Query Neighborhood Hits	190	Target Neighborhood Hits	288	Shared Neighborhood Hits	46
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

CTGF_HUMAN
NC score	0.060400 (rank : 204)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	190	Target Neighborhood Hits	128	Shared Neighborhood Hits	51
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

GP115_HUMAN
NC score	0.060363 (rank : 205)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	190	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GPR97_MOUSE
NC score	0.059440 (rank : 206)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	190	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GP115_MOUSE
NC score	0.059023 (rank : 207)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	190	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

LPHN3_HUMAN
NC score	0.057946 (rank : 208)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	190	Target Neighborhood Hits	139	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

KR106_HUMAN
NC score	0.057249 (rank : 209)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	190	Target Neighborhood Hits	347	Shared Neighborhood Hits	59
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

GPR97_HUMAN
NC score	0.057185 (rank : 210)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	190	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

BMPER_HUMAN
NC score	0.056907 (rank : 211)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	190	Target Neighborhood Hits	175	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

LPHN1_HUMAN
NC score	0.056853 (rank : 212)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	190	Target Neighborhood Hits	155	Shared Neighborhood Hits	9
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

GPR64_HUMAN
NC score	0.056130 (rank : 213)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	190	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

LPHN2_HUMAN
NC score	0.056096 (rank : 214)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	190	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

GP144_HUMAN
NC score	0.055292 (rank : 215)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	190	Target Neighborhood Hits	108	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

VWF_MOUSE
NC score	0.055236 (rank : 216)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	190	Target Neighborhood Hits	381	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ADAM2_MOUSE
NC score	0.054837 (rank : 217)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	190	Target Neighborhood Hits	209	Shared Neighborhood Hits	58
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

GPR64_MOUSE
NC score	0.054828 (rank : 218)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	190	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

BMPER_MOUSE
NC score	0.054519 (rank : 219)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	190	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

KR104_HUMAN
NC score	0.054020 (rank : 220)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	190	Target Neighborhood Hits	313	Shared Neighborhood Hits	48
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

GP111_HUMAN
NC score	0.053239 (rank : 221)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	190	Target Neighborhood Hits	77	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

GP112_HUMAN
NC score	0.052963 (rank : 222)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	190	Target Neighborhood Hits	441	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

LRP2_HUMAN
NC score	0.052326 (rank : 223)	θ value	1.38821 (rank : 150)
Query Neighborhood Hits	190	Target Neighborhood Hits	573	Shared Neighborhood Hits	60
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ROBO4_MOUSE
NC score	0.052126 (rank : 224)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	190	Target Neighborhood Hits	358	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

GP128_MOUSE
NC score	0.051999 (rank : 225)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	190	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

ADA32_HUMAN
NC score	0.051546 (rank : 226)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	190	Target Neighborhood Hits	216	Shared Neighborhood Hits	54
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

MEGF6_HUMAN
NC score	0.051462 (rank : 227)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	190	Target Neighborhood Hits	671	Shared Neighborhood Hits	75
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KR107_HUMAN
NC score	0.051385 (rank : 228)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	190	Target Neighborhood Hits	330	Shared Neighborhood Hits	53
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

ADA17_MOUSE
NC score	0.051108 (rank : 229)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	190	Target Neighborhood Hits	201	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

NELL1_HUMAN
NC score	0.050675 (rank : 230)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	190	Target Neighborhood Hits	451	Shared Neighborhood Hits	50
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

ADA17_HUMAN
NC score	0.050308 (rank : 231)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	190	Target Neighborhood Hits	223	Shared Neighborhood Hits	52
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA32_MOUSE
NC score	0.050166 (rank : 232)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	190	Target Neighborhood Hits	219	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

GP114_HUMAN
NC score	0.050106 (rank : 233)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	190	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

KR102_HUMAN
NC score	0.050070 (rank : 234)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	190	Target Neighborhood Hits	264	Shared Neighborhood Hits	47
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

RSPO2_HUMAN
NC score	0.049853 (rank : 235)	θ value	6.88961 (rank : 183)
Query Neighborhood Hits	190	Target Neighborhood Hits	90	Shared Neighborhood Hits	35
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

LRP4_HUMAN
NC score	0.048373 (rank : 236)	θ value	0.21417 (rank : 138)
Query Neighborhood Hits	190	Target Neighborhood Hits	355	Shared Neighborhood Hits	42
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP8_MOUSE
NC score	0.047994 (rank : 237)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	190	Target Neighborhood Hits	385	Shared Neighborhood Hits	49
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP4_MOUSE
NC score	0.046917 (rank : 238)	θ value	0.0431538 (rank : 127)
Query Neighborhood Hits	190	Target Neighborhood Hits	351	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP1B_HUMAN
NC score	0.046551 (rank : 239)	θ value	0.279714 (rank : 139)
Query Neighborhood Hits	190	Target Neighborhood Hits	602	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TENX_HUMAN
NC score	0.045563 (rank : 240)	θ value	0.0961366 (rank : 130)
Query Neighborhood Hits	190	Target Neighborhood Hits	789	Shared Neighborhood Hits	76
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LRP1B_MOUSE
NC score	0.044768 (rank : 241)	θ value	0.813845 (rank : 145)
Query Neighborhood Hits	190	Target Neighborhood Hits	606	Shared Neighborhood Hits	61
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

CELR2_HUMAN
NC score	0.044650 (rank : 242)	θ value	0.47712 (rank : 141)
Query Neighborhood Hits	190	Target Neighborhood Hits	657	Shared Neighborhood Hits	52
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

PCSK5_MOUSE
NC score	0.044541 (rank : 243)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	190	Target Neighborhood Hits	613	Shared Neighborhood Hits	67
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

STAB2_HUMAN
NC score	0.043801 (rank : 244)	θ value	0.125558 (rank : 133)
Query Neighborhood Hits	190	Target Neighborhood Hits	534	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

KRA59_HUMAN
NC score	0.042612 (rank : 245)	θ value	0.125558 (rank : 132)
Query Neighborhood Hits	190	Target Neighborhood Hits	310	Shared Neighborhood Hits	32
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

NOTC3_MOUSE
NC score	0.042426 (rank : 246)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	190	Target Neighborhood Hits	975	Shared Neighborhood Hits	72
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.041229 (rank : 247)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	190	Target Neighborhood Hits	1062	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SREC_HUMAN
NC score	0.040706 (rank : 248)	θ value	0.163984 (rank : 135)
Query Neighborhood Hits	190	Target Neighborhood Hits	645	Shared Neighborhood Hits	66
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

KRA58_HUMAN
NC score	0.039732 (rank : 249)	θ value	0.163984 (rank : 134)
Query Neighborhood Hits	190	Target Neighborhood Hits	324	Shared Neighborhood Hits	33
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

CELR2_MOUSE
NC score	0.039332 (rank : 250)	θ value	1.38821 (rank : 148)
Query Neighborhood Hits	190	Target Neighborhood Hits	584	Shared Neighborhood Hits	44
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

FBLN1_MOUSE
NC score	0.039110 (rank : 251)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	190	Target Neighborhood Hits	329	Shared Neighborhood Hits	41
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

JAG2_HUMAN
NC score	0.038795 (rank : 252)	θ value	0.62314 (rank : 143)
Query Neighborhood Hits	190	Target Neighborhood Hits	491	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

KRA53_HUMAN
NC score	0.037235 (rank : 253)	θ value	0.0563607 (rank : 128)
Query Neighborhood Hits	190	Target Neighborhood Hits	331	Shared Neighborhood Hits	37
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

NOTC1_HUMAN
NC score	0.037172 (rank : 254)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	190	Target Neighborhood Hits	906	Shared Neighborhood Hits	67
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CRUM1_HUMAN
NC score	0.036799 (rank : 255)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	190	Target Neighborhood Hits	457	Shared Neighborhood Hits	53
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DLL3_HUMAN
NC score	0.033270 (rank : 256)	θ value	0.0961366 (rank : 129)
Query Neighborhood Hits	190	Target Neighborhood Hits	419	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

MK_MOUSE
NC score	0.032817 (rank : 257)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	190	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	P12025	Gene names	Mdk, Mk
Domain Architecture
Description	Midkine precursor (MK) (Retinoic acid-induced differentiation factor).

DLL3_MOUSE
NC score	0.031925 (rank : 258)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	190	Target Neighborhood Hits	399	Shared Neighborhood Hits	48
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

MET_MOUSE
NC score	0.026754 (rank : 259)	θ value	0.279714 (rank : 140)
Query Neighborhood Hits	190	Target Neighborhood Hits	844	Shared Neighborhood Hits	25
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

KRA55_HUMAN
NC score	0.022331 (rank : 260)	θ value	6.88961 (rank : 180)
Query Neighborhood Hits	190	Target Neighborhood Hits	257	Shared Neighborhood Hits	28
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LYAM3_MOUSE
NC score	0.020308 (rank : 261)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	190	Target Neighborhood Hits	390	Shared Neighborhood Hits	36
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

ITB6_MOUSE
NC score	0.018888 (rank : 262)	θ value	6.88961 (rank : 179)
Query Neighborhood Hits	190	Target Neighborhood Hits	341	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMC1_HUMAN
NC score	0.017412 (rank : 263)	θ value	1.38821 (rank : 149)
Query Neighborhood Hits	190	Target Neighborhood Hits	922	Shared Neighborhood Hits	49
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LYAM3_HUMAN
NC score	0.016992 (rank : 264)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	190	Target Neighborhood Hits	378	Shared Neighborhood Hits	36
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

IL4RA_HUMAN
NC score	0.015933 (rank : 265)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	190	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

PRKN2_MOUSE
NC score	0.015061 (rank : 266)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	190	Target Neighborhood Hits	69	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

LAMA3_MOUSE
NC score	0.014440 (rank : 267)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	190	Target Neighborhood Hits	859	Shared Neighborhood Hits	54
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

PAPPA_HUMAN
NC score	0.013722 (rank : 268)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	190	Target Neighborhood Hits	161	Shared Neighborhood Hits	25
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PNKP_MOUSE
NC score	0.009330 (rank : 269)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	190	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLV6, Q6PFA3	Gene names	Pnkp
Domain Architecture	No domain graphic available
Description	Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase- 3'-phosphatase) (DNA 5'-kinase/3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2'(3')-polynucleotidase); Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78)].

VMO1_MOUSE
NC score	0.007721 (rank : 270)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	190	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SXG7	Gene names	Vmo1, Gm741
Domain Architecture	No domain graphic available
Description	Vitelline membrane outer layer protein 1 homolog precursor.

SHPS1_HUMAN
NC score	0.007570 (rank : 271)	θ value	1.06291 (rank : 146)
Query Neighborhood Hits	190	Target Neighborhood Hits	455	Shared Neighborhood Hits	3
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

KR132_HUMAN
NC score	0.007219 (rank : 272)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	190	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

GP143_MOUSE
NC score	0.005843 (rank : 273)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	190	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P70259, O89031	Gene names	Gpr143, Oa1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein homolog) (MOA1).

LYPD5_HUMAN
NC score	0.005413 (rank : 274)	θ value	6.88961 (rank : 181)
Query Neighborhood Hits	190	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UWN5, Q6PEX9, Q96DR2	Gene names	LYPD5
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 5 precursor.

KCNH2_MOUSE
NC score	0.004565 (rank : 275)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	190	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

ELOA2_HUMAN
NC score	0.003504 (rank : 276)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	190	Target Neighborhood Hits	165	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

FINC_HUMAN
NC score	0.002174 (rank : 277)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	190	Target Neighborhood Hits	302	Shared Neighborhood Hits	8
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

UFO_MOUSE
NC score	-0.000557 (rank : 278)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	190	Target Neighborhood Hits	988	Shared Neighborhood Hits	17
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

ERBB3_HUMAN
NC score	-0.001166 (rank : 279)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	190	Target Neighborhood Hits	918	Shared Neighborhood Hits	19
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

RHEB_MOUSE
NC score	-0.003779 (rank : 280)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	190	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q921J2	Gene names	Rheb
Domain Architecture
Description	GTP-binding protein Rheb (Ras homolog enriched in brain).

RHEB_HUMAN
NC score	-0.003782 (rank : 281)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	190	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q15382, Q99444	Gene names	RHEB, RHEB2
Domain Architecture
Description	GTP-binding protein Rheb (Ras homolog enriched in brain).