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Network neighborhood for query Sequence : SEM6A_MOUSE

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SEM6A_MOUSE
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SEM6A_HUMAN
θ value	0 (rank : 1)	NC score	0.999321 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM6A_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SEM6B_HUMAN
θ value	0 (rank : 3)	NC score	0.986446 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	187	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SEM6B_MOUSE
θ value	0 (rank : 4)	NC score	0.984207 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	200	Shared Neighborhood Hits	54
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SEM6D_HUMAN
θ value	0 (rank : 5)	NC score	0.987146 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	169	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6D_MOUSE
θ value	0 (rank : 6)	NC score	0.987648 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	161	Shared Neighborhood Hits	61
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6C_HUMAN
θ value	9.17788e-162 (rank : 7)	NC score	0.984220 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6C_MOUSE
θ value	8.88953e-157 (rank : 8)	NC score	0.968118 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	352	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM3A_MOUSE
θ value	3.44927e-84 (rank : 9)	NC score	0.943340 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	92	Shared Neighborhood Hits	53
SwissProt Accessions	O08665, Q5BL08, Q62180, Q62215	Gene names	Sema3a, Semad, SemD
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III) (Semaphorin D) (Sema D).

SEM5A_HUMAN
θ value	4.50487e-84 (rank : 10)	NC score	0.799423 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	177	Shared Neighborhood Hits	53
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	4.50487e-84 (rank : 11)	NC score	0.804463 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM3A_HUMAN
θ value	3.81361e-83 (rank : 12)	NC score	0.943289 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	78	Shared Neighborhood Hits	53
SwissProt Accessions	Q14563	Gene names	SEMA3A
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III).

SEM3B_HUMAN
θ value	5.15425e-80 (rank : 13)	NC score	0.947249 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

SEM5B_HUMAN
θ value	1.14825e-79 (rank : 14)	NC score	0.803782 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	178	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5B_MOUSE
θ value	5.69867e-79 (rank : 15)	NC score	0.801163 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	190	Shared Neighborhood Hits	53
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM3B_MOUSE
θ value	8.22888e-78 (rank : 16)	NC score	0.946467 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	75	Shared Neighborhood Hits	53
SwissProt Accessions	Q62177	Gene names	Sema3b, Sema, Semaa
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin A) (Sema A).

SEM3D_MOUSE
θ value	5.8972e-76 (rank : 17)	NC score	0.940214 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	97	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

SEM3D_HUMAN
θ value	2.24094e-75 (rank : 18)	NC score	0.940604 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	104	Shared Neighborhood Hits	51
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

SEM3E_HUMAN
θ value	6.10265e-73 (rank : 19)	NC score	0.942386 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	73	Shared Neighborhood Hits	53
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

SEM3C_MOUSE
θ value	1.7756e-72 (rank : 20)	NC score	0.939271 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	53
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3C_HUMAN
θ value	3.02872e-72 (rank : 21)	NC score	0.939030 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3E_MOUSE
θ value	3.95564e-72 (rank : 22)	NC score	0.940716 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM4D_MOUSE
θ value	6.7473e-72 (rank : 23)	NC score	0.943886 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SEM4D_HUMAN
θ value	4.37348e-71 (rank : 24)	NC score	0.942895 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	139	Shared Neighborhood Hits	53
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

SEM3F_MOUSE
θ value	8.24801e-70 (rank : 25)	NC score	0.941181 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEM3F_HUMAN
θ value	9.11921e-69 (rank : 26)	NC score	0.940146 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	100	Shared Neighborhood Hits	53
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEM4C_MOUSE
θ value	5.00389e-67 (rank : 27)	NC score	0.944929 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	77	Shared Neighborhood Hits	53
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM4C_HUMAN
θ value	3.24342e-66 (rank : 28)	NC score	0.944024 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	84	Shared Neighborhood Hits	53
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SEM4A_HUMAN
θ value	4.68348e-65 (rank : 29)	NC score	0.945524 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4B_HUMAN
θ value	1.04338e-64 (rank : 30)	NC score	0.943287 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NPR2, Q6UXE3, Q8WVP9, Q96FK5, Q9C0B8, Q9H691, Q9NPM8, Q9NPN0	Gene names	SEMA4B, KIAA1745
Domain Architecture
Description	Semaphorin-4B precursor.

SEM4B_MOUSE
θ value	2.56992e-63 (rank : 31)	NC score	0.942217 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	67	Shared Neighborhood Hits	53
SwissProt Accessions	Q62179, Q4PKI6, Q69ZB7	Gene names	Sema4b, Kiaa1745, Semac, SemC
Domain Architecture	No domain graphic available
Description	Semaphorin-4B precursor (Semaphorin C) (Sema C).

SEM4A_MOUSE
θ value	1.07972e-61 (rank : 32)	NC score	0.944150 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	65	Shared Neighborhood Hits	53
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4F_MOUSE
θ value	1.55911e-60 (rank : 33)	NC score	0.944877 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	59	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

SEM4F_HUMAN
θ value	3.47335e-60 (rank : 34)	NC score	0.943272 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	57	Shared Neighborhood Hits	53
SwissProt Accessions	O95754, Q9NS35	Gene names	SEMA4F, SEMAM, SEMAW
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W) (Semaphorin M) (Sema M).

SEM4G_HUMAN
θ value	1.01059e-59 (rank : 35)	NC score	0.937664 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	88	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NTN9, Q9HCF3	Gene names	SEMA4G, KIAA1619
Domain Architecture
Description	Semaphorin-4G precursor.

SEM4G_MOUSE
θ value	9.45883e-58 (rank : 36)	NC score	0.936013 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	99	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SEM7A_HUMAN
θ value	1.24399e-33 (rank : 37)	NC score	0.912966 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	67	Shared Neighborhood Hits	53
SwissProt Accessions	O75326	Gene names	SEMA7A, CD108, SEMAL
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (John-Milton-Hargen human blood group Ag) (JMH blood group antigen) (CD108 antigen) (CDw108).

SEM7A_MOUSE
θ value	1.37539e-32 (rank : 38)	NC score	0.910639 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	64	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QUR8, O88371	Gene names	Sema7a, Cd108, Semal, Semk1
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (CD108 antigen) (CDw108).

PLXB1_HUMAN
θ value	8.11959e-09 (rank : 39)	NC score	0.337714 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	360	Shared Neighborhood Hits	58
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PLXB1_MOUSE
θ value	1.06045e-08 (rank : 40)	NC score	0.339763 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	259	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PLXB2_HUMAN
θ value	8.97725e-08 (rank : 41)	NC score	0.394676 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	94	Shared Neighborhood Hits	53
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

PLXA2_HUMAN
θ value	9.92553e-07 (rank : 42)	NC score	0.341252 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	100	Shared Neighborhood Hits	53
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

PLXA2_MOUSE
θ value	9.92553e-07 (rank : 43)	NC score	0.338923 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	97	Shared Neighborhood Hits	52
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

PLXB3_HUMAN
θ value	1.87187e-05 (rank : 44)	NC score	0.306610 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

PLXA4_HUMAN
θ value	4.1701e-05 (rank : 45)	NC score	0.355347 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXB3_MOUSE
θ value	0.000121331 (rank : 46)	NC score	0.307149 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	94	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

PLXA4_MOUSE
θ value	0.000158464 (rank : 47)	NC score	0.354524 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	109	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA1_HUMAN
θ value	0.00020696 (rank : 48)	NC score	0.326991 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	108	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

PLXA1_MOUSE
θ value	0.00035302 (rank : 49)	NC score	0.332742 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	107	Shared Neighborhood Hits	53
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

PLXC1_MOUSE
θ value	0.000602161 (rank : 50)	NC score	0.356913 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	84	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QZC2, Q8CGW1	Gene names	Plxnc1, Vespr
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXA3_HUMAN
θ value	0.00102713 (rank : 51)	NC score	0.321588 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	P51805	Gene names	PLXNA3, PLXN4, SEX
Domain Architecture
Description	Plexin-A3 precursor (Plexin-4) (Semaphorin receptor SEX).

PLXC1_HUMAN
θ value	0.0113563 (rank : 52)	NC score	0.345773 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	94	Shared Neighborhood Hits	53
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXD1_HUMAN
θ value	0.0252991 (rank : 53)	NC score	0.287732 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

MLL2_HUMAN
θ value	0.125558 (rank : 54)	NC score	0.016144 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	1788	Shared Neighborhood Hits	24
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ZYX_MOUSE
θ value	0.21417 (rank : 55)	NC score	0.013580 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	347	Shared Neighborhood Hits	8
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

FGD1_HUMAN
θ value	0.365318 (rank : 56)	NC score	0.016531 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	367	Shared Neighborhood Hits	10
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_MOUSE
θ value	1.06291 (rank : 57)	NC score	0.018848 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	387	Shared Neighborhood Hits	10
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

APS_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.013096 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

LAP2_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.001869 (rank : 107)
Query Neighborhood Hits	96	Target Neighborhood Hits	482	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

IL3RB_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.010447 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

MDC1_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.010104 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	1446	Shared Neighborhood Hits	20
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PHAR1_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.009367 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

SFR15_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.014407 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

GATA5_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.010152 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BWX5	Gene names	GATA5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

ZDH17_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.008241 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	334	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ZDH17_MOUSE
θ value	2.36792 (rank : 66)	NC score	0.008421 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	328	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

K0195_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.011063 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

MAP4_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.009964 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	409	Shared Neighborhood Hits	8
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RAPH1_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.007765 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	593	Shared Neighborhood Hits	9
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RHG12_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.004816 (rank : 100)
Query Neighborhood Hits	96	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SI1L1_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.004255 (rank : 101)
Query Neighborhood Hits	96	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

MINK1_MOUSE
θ value	4.03905 (rank : 72)	NC score	-0.003534 (rank : 113)
Query Neighborhood Hits	96	Target Neighborhood Hits	1451	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINT_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.008481 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	1291	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

AKAP6_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.008485 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	263	Shared Neighborhood Hits	8
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

ALK_MOUSE
θ value	5.27518 (rank : 75)	NC score	-0.003778 (rank : 114)
Query Neighborhood Hits	96	Target Neighborhood Hits	811	Shared Neighborhood Hits	8
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

EP400_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.010224 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	592	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

FXR2_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.006931 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

KIF12_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.003115 (rank : 103)
Query Neighborhood Hits	96	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D2Z8, O35061	Gene names	Kif12
Domain Architecture
Description	Kinesin-like protein KIF12.

MLL3_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.005024 (rank : 99)
Query Neighborhood Hits	96	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NRP1_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.002162 (rank : 106)
Query Neighborhood Hits	96	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.002252 (rank : 105)
Query Neighborhood Hits	96	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

KLF2_MOUSE
θ value	6.88961 (rank : 82)	NC score	-0.003408 (rank : 111)
Query Neighborhood Hits	96	Target Neighborhood Hits	738	Shared Neighborhood Hits	5
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

M3K10_HUMAN
θ value	6.88961 (rank : 83)	NC score	-0.004798 (rank : 117)
Query Neighborhood Hits	96	Target Neighborhood Hits	1071	Shared Neighborhood Hits	9
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

MK15_HUMAN
θ value	6.88961 (rank : 84)	NC score	-0.005337 (rank : 119)
Query Neighborhood Hits	96	Target Neighborhood Hits	1038	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).

RRBP1_HUMAN
θ value	6.88961 (rank : 85)	NC score	-0.002315 (rank : 109)
Query Neighborhood Hits	96	Target Neighborhood Hits	1306	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

WNK4_MOUSE
θ value	6.88961 (rank : 86)	NC score	-0.004282 (rank : 116)
Query Neighborhood Hits	96	Target Neighborhood Hits	961	Shared Neighborhood Hits	9
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

F262_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.006044 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	O60825, O60824, Q9H3P1	Gene names	PFKFB2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

KLF2_HUMAN
θ value	8.99809 (rank : 88)	NC score	-0.002584 (rank : 110)
Query Neighborhood Hits	96	Target Neighborhood Hits	755	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5W3, Q9UJS5, Q9UKR6	Gene names	KLF2, LKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

MAGC1_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.002911 (rank : 104)
Query Neighborhood Hits	96	Target Neighborhood Hits	431	Shared Neighborhood Hits	9
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MILK1_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.006066 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

RRBP1_MOUSE
θ value	8.99809 (rank : 91)	NC score	-0.003451 (rank : 112)
Query Neighborhood Hits	96	Target Neighborhood Hits	1650	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SNRK_HUMAN
θ value	8.99809 (rank : 92)	NC score	-0.005330 (rank : 118)
Query Neighborhood Hits	96	Target Neighborhood Hits	855	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

SNTG2_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.000585 (rank : 108)
Query Neighborhood Hits	96	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

SYNPO_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.009637 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

VATA1_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.003312 (rank : 102)
Query Neighborhood Hits	96	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	P38606, Q96DY6, Q9UHY3	Gene names	ATP6V1A, ATP6A1, ATP6V1A1, VPP2
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68).

WNK1_MOUSE
θ value	8.99809 (rank : 96)	NC score	-0.003849 (rank : 115)
Query Neighborhood Hits	96	Target Neighborhood Hits	1179	Shared Neighborhood Hits	16
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

BAI1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.057365 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	375	Shared Neighborhood Hits	7
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.057073 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	340	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.053702 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.053762 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	323	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.052236 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.054296 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	250	Shared Neighborhood Hits	5
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

PROP_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.099993 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.097237 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SPON1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.072480 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.074153 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SSPO_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.054883 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	800	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

THSD1_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.050673 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TSP1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.051054 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	389	Shared Neighborhood Hits	4
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.051405 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	396	Shared Neighborhood Hits	4
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.052444 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	359	Shared Neighborhood Hits	4
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.053653 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

UNC5A_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.059453 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	203	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.061941 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.061008 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	226	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.057387 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.058145 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.068606 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	267	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.068488 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	268	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

Hits sorted by NC score

SEM6A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	96
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

SEM6A_HUMAN
NC score	0.999321 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	96	Target Neighborhood Hits	96	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H2E6, Q9P2H9	Gene names	SEMA6A, KIAA1368
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1).

SEM6D_MOUSE
NC score	0.987648 (rank : 3)	θ value	0 (rank : 6)
Query Neighborhood Hits	96	Target Neighborhood Hits	161	Shared Neighborhood Hits	61
SwissProt Accessions	Q76KF0, Q76KF1, Q76KF2, Q76KF3, Q76KF4, Q80TD0	Gene names	Sema6d, Kiaa1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6D_HUMAN
NC score	0.987146 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	96	Target Neighborhood Hits	169	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NFY4, Q8NFY3, Q8NFY5, Q8NFY6, Q8NFY7, Q9P249	Gene names	SEMA6D, KIAA1479
Domain Architecture	No domain graphic available
Description	Semaphorin-6D precursor.

SEM6B_HUMAN
NC score	0.986446 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	96	Target Neighborhood Hits	187	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

SEM6C_HUMAN
NC score	0.984220 (rank : 6)	θ value	9.17788e-162 (rank : 7)
Query Neighborhood Hits	96	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM6B_MOUSE
NC score	0.984207 (rank : 7)	θ value	0 (rank : 4)
Query Neighborhood Hits	96	Target Neighborhood Hits	200	Shared Neighborhood Hits	54
SwissProt Accessions	O54951	Gene names	Sema6b, Seman
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin VIB) (Sema VIB) (Semaphorin N) (Sema N).

SEM6C_MOUSE
NC score	0.968118 (rank : 8)	θ value	8.88953e-157 (rank : 8)
Query Neighborhood Hits	96	Target Neighborhood Hits	352	Shared Neighborhood Hits	56
SwissProt Accessions	Q9WTM3	Gene names	Sema6c, Semay
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SEM3B_HUMAN
NC score	0.947249 (rank : 9)	θ value	5.15425e-80 (rank : 13)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	Q13214, Q8TB71, Q8TDV7, Q93018, Q96GX0	Gene names	SEMA3B, SEMA5
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin V) (Sema V) (Sema A(V)).

SEM3B_MOUSE
NC score	0.946467 (rank : 10)	θ value	8.22888e-78 (rank : 16)
Query Neighborhood Hits	96	Target Neighborhood Hits	75	Shared Neighborhood Hits	53
SwissProt Accessions	Q62177	Gene names	Sema3b, Sema, Semaa
Domain Architecture
Description	Semaphorin-3B precursor (Semaphorin A) (Sema A).

SEM4A_HUMAN
NC score	0.945524 (rank : 11)	θ value	4.68348e-65 (rank : 29)
Query Neighborhood Hits	96	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H3S1, Q8WUA9	Gene names	SEMA4A, SEMB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4C_MOUSE
NC score	0.944929 (rank : 12)	θ value	5.00389e-67 (rank : 27)
Query Neighborhood Hits	96	Target Neighborhood Hits	77	Shared Neighborhood Hits	53
SwissProt Accessions	Q64151	Gene names	Sema4c, Semacl1, Semai
Domain Architecture
Description	Semaphorin-4C precursor (Semaphorin I) (Sema I) (Semaphorin C-like 1) (M-Sema F).

SEM4F_MOUSE
NC score	0.944877 (rank : 13)	θ value	1.55911e-60 (rank : 33)
Query Neighborhood Hits	96	Target Neighborhood Hits	59	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Z123, Q9R1Y1	Gene names	Sema4f, Semaw
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W).

SEM4A_MOUSE
NC score	0.944150 (rank : 14)	θ value	1.07972e-61 (rank : 32)
Query Neighborhood Hits	96	Target Neighborhood Hits	65	Shared Neighborhood Hits	53
SwissProt Accessions	Q62178	Gene names	Sema4a, Semab, SemB
Domain Architecture
Description	Semaphorin-4A precursor (Semaphorin B) (Sema B).

SEM4C_HUMAN
NC score	0.944024 (rank : 15)	θ value	3.24342e-66 (rank : 28)
Query Neighborhood Hits	96	Target Neighborhood Hits	84	Shared Neighborhood Hits	53
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SEM4D_MOUSE
NC score	0.943886 (rank : 16)	θ value	6.7473e-72 (rank : 23)
Query Neighborhood Hits	96	Target Neighborhood Hits	143	Shared Neighborhood Hits	55
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

SEM3A_MOUSE
NC score	0.943340 (rank : 17)	θ value	3.44927e-84 (rank : 9)
Query Neighborhood Hits	96	Target Neighborhood Hits	92	Shared Neighborhood Hits	53
SwissProt Accessions	O08665, Q5BL08, Q62180, Q62215	Gene names	Sema3a, Semad, SemD
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III) (Semaphorin D) (Sema D).

SEM3A_HUMAN
NC score	0.943289 (rank : 18)	θ value	3.81361e-83 (rank : 12)
Query Neighborhood Hits	96	Target Neighborhood Hits	78	Shared Neighborhood Hits	53
SwissProt Accessions	Q14563	Gene names	SEMA3A
Domain Architecture
Description	Semaphorin-3A precursor (Semaphorin III) (Sema III).

SEM4B_HUMAN
NC score	0.943287 (rank : 19)	θ value	1.04338e-64 (rank : 30)
Query Neighborhood Hits	96	Target Neighborhood Hits	67	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NPR2, Q6UXE3, Q8WVP9, Q96FK5, Q9C0B8, Q9H691, Q9NPM8, Q9NPN0	Gene names	SEMA4B, KIAA1745
Domain Architecture
Description	Semaphorin-4B precursor.

SEM4F_HUMAN
NC score	0.943272 (rank : 20)	θ value	3.47335e-60 (rank : 34)
Query Neighborhood Hits	96	Target Neighborhood Hits	57	Shared Neighborhood Hits	53
SwissProt Accessions	O95754, Q9NS35	Gene names	SEMA4F, SEMAM, SEMAW
Domain Architecture
Description	Semaphorin-4F precursor (Semaphorin W) (Sema W) (Semaphorin M) (Sema M).

SEM4D_HUMAN
NC score	0.942895 (rank : 21)	θ value	4.37348e-71 (rank : 24)
Query Neighborhood Hits	96	Target Neighborhood Hits	139	Shared Neighborhood Hits	53
SwissProt Accessions	Q92854, Q7Z5S4	Gene names	SEMA4D, CD100
Domain Architecture
Description	Semaphorin-4D precursor (Leukocyte activation antigen CD100) (BB18) (A8) (GR3).

SEM3E_HUMAN
NC score	0.942386 (rank : 22)	θ value	6.10265e-73 (rank : 19)
Query Neighborhood Hits	96	Target Neighborhood Hits	73	Shared Neighborhood Hits	53
SwissProt Accessions	O15041, Q75M94, Q75M97	Gene names	SEMA3E, KIAA0331
Domain Architecture	No domain graphic available
Description	Semaphorin-3E precursor.

SEM4B_MOUSE
NC score	0.942217 (rank : 23)	θ value	2.56992e-63 (rank : 31)
Query Neighborhood Hits	96	Target Neighborhood Hits	67	Shared Neighborhood Hits	53
SwissProt Accessions	Q62179, Q4PKI6, Q69ZB7	Gene names	Sema4b, Kiaa1745, Semac, SemC
Domain Architecture	No domain graphic available
Description	Semaphorin-4B precursor (Semaphorin C) (Sema C).

SEM3F_MOUSE
NC score	0.941181 (rank : 24)	θ value	8.24801e-70 (rank : 25)
Query Neighborhood Hits	96	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	O88632, O88633	Gene names	Sema3f
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV).

SEM3E_MOUSE
NC score	0.940716 (rank : 25)	θ value	3.95564e-72 (rank : 22)
Query Neighborhood Hits	96	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

SEM3D_HUMAN
NC score	0.940604 (rank : 26)	θ value	2.24094e-75 (rank : 18)
Query Neighborhood Hits	96	Target Neighborhood Hits	104	Shared Neighborhood Hits	51
SwissProt Accessions	O95025, Q6UW77, Q8NCQ1	Gene names	SEMA3D
Domain Architecture
Description	Semaphorin-3D precursor.

SEM3D_MOUSE
NC score	0.940214 (rank : 27)	θ value	5.8972e-76 (rank : 17)
Query Neighborhood Hits	96	Target Neighborhood Hits	97	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH34	Gene names	Sema3d
Domain Architecture	No domain graphic available
Description	Semaphorin-3D precursor.

SEM3F_HUMAN
NC score	0.940146 (rank : 28)	θ value	9.11921e-69 (rank : 26)
Query Neighborhood Hits	96	Target Neighborhood Hits	100	Shared Neighborhood Hits	53
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEM3C_MOUSE
NC score	0.939271 (rank : 29)	θ value	1.7756e-72 (rank : 20)
Query Neighborhood Hits	96	Target Neighborhood Hits	113	Shared Neighborhood Hits	53
SwissProt Accessions	Q62181	Gene names	Sema3c, Semae, SemE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM3C_HUMAN
NC score	0.939030 (rank : 30)	θ value	3.02872e-72 (rank : 21)
Query Neighborhood Hits	96	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q99985	Gene names	SEMA3C, SEMAE
Domain Architecture
Description	Semaphorin-3C precursor (Semaphorin E) (Sema E).

SEM4G_HUMAN
NC score	0.937664 (rank : 31)	θ value	1.01059e-59 (rank : 35)
Query Neighborhood Hits	96	Target Neighborhood Hits	88	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NTN9, Q9HCF3	Gene names	SEMA4G, KIAA1619
Domain Architecture
Description	Semaphorin-4G precursor.

SEM4G_MOUSE
NC score	0.936013 (rank : 32)	θ value	9.45883e-58 (rank : 36)
Query Neighborhood Hits	96	Target Neighborhood Hits	99	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WUH7	Gene names	Sema4g
Domain Architecture
Description	Semaphorin-4G precursor.

SEM7A_HUMAN
NC score	0.912966 (rank : 33)	θ value	1.24399e-33 (rank : 37)
Query Neighborhood Hits	96	Target Neighborhood Hits	67	Shared Neighborhood Hits	53
SwissProt Accessions	O75326	Gene names	SEMA7A, CD108, SEMAL
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (John-Milton-Hargen human blood group Ag) (JMH blood group antigen) (CD108 antigen) (CDw108).

SEM7A_MOUSE
NC score	0.910639 (rank : 34)	θ value	1.37539e-32 (rank : 38)
Query Neighborhood Hits	96	Target Neighborhood Hits	64	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QUR8, O88371	Gene names	Sema7a, Cd108, Semal, Semk1
Domain Architecture
Description	Semaphorin-7A precursor (Semaphorin L) (Sema L) (Semaphorin K1) (Sema K1) (CD108 antigen) (CDw108).

SEM5A_MOUSE
NC score	0.804463 (rank : 35)	θ value	4.50487e-84 (rank : 11)
Query Neighborhood Hits	96	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_HUMAN
NC score	0.803782 (rank : 36)	θ value	1.14825e-79 (rank : 14)
Query Neighborhood Hits	96	Target Neighborhood Hits	178	Shared Neighborhood Hits	53
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5B_MOUSE
NC score	0.801163 (rank : 37)	θ value	5.69867e-79 (rank : 15)
Query Neighborhood Hits	96	Target Neighborhood Hits	190	Shared Neighborhood Hits	53
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5A_HUMAN
NC score	0.799423 (rank : 38)	θ value	4.50487e-84 (rank : 10)
Query Neighborhood Hits	96	Target Neighborhood Hits	177	Shared Neighborhood Hits	53
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

PLXB2_HUMAN
NC score	0.394676 (rank : 39)	θ value	8.97725e-08 (rank : 41)
Query Neighborhood Hits	96	Target Neighborhood Hits	94	Shared Neighborhood Hits	53
SwissProt Accessions	O15031, Q7KZU3, Q9BSU7	Gene names	PLXNB2, KIAA0315
Domain Architecture	No domain graphic available
Description	Plexin-B2 precursor (MM1).

PLXC1_MOUSE
NC score	0.356913 (rank : 40)	θ value	0.000602161 (rank : 50)
Query Neighborhood Hits	96	Target Neighborhood Hits	84	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QZC2, Q8CGW1	Gene names	Plxnc1, Vespr
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXA4_HUMAN
NC score	0.355347 (rank : 41)	θ value	4.1701e-05 (rank : 45)
Query Neighborhood Hits	96	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HCM2, Q6UWC6, Q6ZW89, Q8N969, Q8ND00, Q8NEN3, Q9NTD4	Gene names	PLXNA4, KIAA1550, PLXNA4A, PLXNA4B
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXA4_MOUSE
NC score	0.354524 (rank : 42)	θ value	0.000158464 (rank : 47)
Query Neighborhood Hits	96	Target Neighborhood Hits	109	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UG2, Q5DTW8, Q8BKK9	Gene names	Plxna4, Kiaa1550
Domain Architecture	No domain graphic available
Description	Plexin-A4 precursor.

PLXC1_HUMAN
NC score	0.345773 (rank : 43)	θ value	0.0113563 (rank : 52)
Query Neighborhood Hits	96	Target Neighborhood Hits	94	Shared Neighborhood Hits	53
SwissProt Accessions	O60486, Q59H25	Gene names	PLXNC1, VESPR
Domain Architecture	No domain graphic available
Description	Plexin-C1 precursor (Virus-encoded semaphorin protein receptor) (CD232 antigen).

PLXA2_HUMAN
NC score	0.341252 (rank : 44)	θ value	9.92553e-07 (rank : 42)
Query Neighborhood Hits	96	Target Neighborhood Hits	100	Shared Neighborhood Hits	53
SwissProt Accessions	O75051, Q6UX61, Q96GN9, Q9BRL1, Q9UIW1	Gene names	PLXNA2, KIAA0463, OCT
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Semaphorin receptor OCT).

PLXB1_MOUSE
NC score	0.339763 (rank : 45)	θ value	1.06045e-08 (rank : 40)
Query Neighborhood Hits	96	Target Neighborhood Hits	259	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PLXA2_MOUSE
NC score	0.338923 (rank : 46)	θ value	9.92553e-07 (rank : 43)
Query Neighborhood Hits	96	Target Neighborhood Hits	97	Shared Neighborhood Hits	52
SwissProt Accessions	P70207, Q6NVE6, Q6PHN4, Q80TZ7, Q8R1I4	Gene names	Plxna2, Kiaa0463
Domain Architecture	No domain graphic available
Description	Plexin-A2 precursor (Plexin-2) (Plex 2).

PLXB1_HUMAN
NC score	0.337714 (rank : 47)	θ value	8.11959e-09 (rank : 39)
Query Neighborhood Hits	96	Target Neighborhood Hits	360	Shared Neighborhood Hits	58
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PLXA1_MOUSE
NC score	0.332742 (rank : 48)	θ value	0.00035302 (rank : 49)
Query Neighborhood Hits	96	Target Neighborhood Hits	107	Shared Neighborhood Hits	53
SwissProt Accessions	P70206, Q5DTR0	Gene names	Plxna1, KIAA4053
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Plexin-1) (Plex 1).

PLXA1_HUMAN
NC score	0.326991 (rank : 49)	θ value	0.00020696 (rank : 48)
Query Neighborhood Hits	96	Target Neighborhood Hits	108	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UIW2	Gene names	PLXNA1, NOV
Domain Architecture	No domain graphic available
Description	Plexin-A1 precursor (Semaphorin receptor NOV).

PLXA3_HUMAN
NC score	0.321588 (rank : 50)	θ value	0.00102713 (rank : 51)
Query Neighborhood Hits	96	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	P51805	Gene names	PLXNA3, PLXN4, SEX
Domain Architecture
Description	Plexin-A3 precursor (Plexin-4) (Semaphorin receptor SEX).

PLXB3_MOUSE
NC score	0.307149 (rank : 51)	θ value	0.000121331 (rank : 46)
Query Neighborhood Hits	96	Target Neighborhood Hits	94	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

PLXB3_HUMAN
NC score	0.306610 (rank : 52)	θ value	1.87187e-05 (rank : 44)
Query Neighborhood Hits	96	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

PLXD1_HUMAN
NC score	0.287732 (rank : 53)	θ value	0.0252991 (rank : 53)
Query Neighborhood Hits	96	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4D7, Q6PJS9, Q8IZJ2, Q9BTQ2	Gene names	PLXND1, KIAA0620
Domain Architecture	No domain graphic available
Description	Plexin-D1 precursor.

PROP_HUMAN
NC score	0.099993 (rank : 54)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	96	Target Neighborhood Hits	126	Shared Neighborhood Hits	4
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
NC score	0.097237 (rank : 55)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	96	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SPON1_MOUSE
NC score	0.074153 (rank : 56)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	96	Target Neighborhood Hits	123	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
NC score	0.072480 (rank : 57)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	96	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

UNC5D_HUMAN
NC score	0.068606 (rank : 58)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	96	Target Neighborhood Hits	267	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
NC score	0.068488 (rank : 59)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	96	Target Neighborhood Hits	268	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5B_HUMAN
NC score	0.061941 (rank : 60)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	96	Target Neighborhood Hits	225	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
NC score	0.061008 (rank : 61)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	96	Target Neighborhood Hits	226	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5A_MOUSE
NC score	0.059453 (rank : 62)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	96	Target Neighborhood Hits	203	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5C_MOUSE
NC score	0.058145 (rank : 63)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	96	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.057387 (rank : 64)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	96	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

BAI1_HUMAN
NC score	0.057365 (rank : 65)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	96	Target Neighborhood Hits	375	Shared Neighborhood Hits	7
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
NC score	0.057073 (rank : 66)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	96	Target Neighborhood Hits	340	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

SSPO_MOUSE
NC score	0.054883 (rank : 67)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	96	Target Neighborhood Hits	800	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

BAI3_MOUSE
NC score	0.054296 (rank : 68)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	96	Target Neighborhood Hits	250	Shared Neighborhood Hits	5
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI2_MOUSE
NC score	0.053762 (rank : 69)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	96	Target Neighborhood Hits	323	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
NC score	0.053702 (rank : 70)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	96	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TSP2_MOUSE
NC score	0.053653 (rank : 71)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	96	Target Neighborhood Hits	352	Shared Neighborhood Hits	4
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_HUMAN
NC score	0.052444 (rank : 72)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	96	Target Neighborhood Hits	359	Shared Neighborhood Hits	4
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

BAI3_HUMAN
NC score	0.052236 (rank : 73)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	96	Target Neighborhood Hits	246	Shared Neighborhood Hits	4
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

TSP1_MOUSE
NC score	0.051405 (rank : 74)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	96	Target Neighborhood Hits	396	Shared Neighborhood Hits	4
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_HUMAN
NC score	0.051054 (rank : 75)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	96	Target Neighborhood Hits	389	Shared Neighborhood Hits	4
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

THSD1_HUMAN
NC score	0.050673 (rank : 76)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	96	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

FGD1_MOUSE
NC score	0.018848 (rank : 77)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	96	Target Neighborhood Hits	387	Shared Neighborhood Hits	10
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FGD1_HUMAN
NC score	0.016531 (rank : 78)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	96	Target Neighborhood Hits	367	Shared Neighborhood Hits	10
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

MLL2_HUMAN
NC score	0.016144 (rank : 79)	θ value	0.125558 (rank : 54)
Query Neighborhood Hits	96	Target Neighborhood Hits	1788	Shared Neighborhood Hits	24
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SFR15_HUMAN
NC score	0.014407 (rank : 80)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	96	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

ZYX_MOUSE
NC score	0.013580 (rank : 81)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	96	Target Neighborhood Hits	347	Shared Neighborhood Hits	8
SwissProt Accessions	Q62523, P70461	Gene names	Zyx
Domain Architecture
Description	Zyxin.

APS_MOUSE
NC score	0.013096 (rank : 82)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	96	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JID9, O88936	Gene names	Aps
Domain Architecture
Description	SH2 and PH domain-containing adapter protein APS (Adapter protein with pleckstrin homology and Src homology 2 domains).

K0195_HUMAN
NC score	0.011063 (rank : 83)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	96	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

IL3RB_HUMAN
NC score	0.010447 (rank : 84)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	96	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

EP400_MOUSE
NC score	0.010224 (rank : 85)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	96	Target Neighborhood Hits	592	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

GATA5_HUMAN
NC score	0.010152 (rank : 86)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	96	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BWX5	Gene names	GATA5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

MDC1_HUMAN
NC score	0.010104 (rank : 87)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	96	Target Neighborhood Hits	1446	Shared Neighborhood Hits	20
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MAP4_MOUSE
NC score	0.009964 (rank : 88)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	96	Target Neighborhood Hits	409	Shared Neighborhood Hits	8
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SYNPO_MOUSE
NC score	0.009637 (rank : 89)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	96	Target Neighborhood Hits	242	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CC35, Q99JI0	Gene names	Synpo, Kiaa1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

PHAR1_MOUSE
NC score	0.009367 (rank : 90)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	96	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

AKAP6_HUMAN
NC score	0.008485 (rank : 91)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	96	Target Neighborhood Hits	263	Shared Neighborhood Hits	8
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

MINT_HUMAN
NC score	0.008481 (rank : 92)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	96	Target Neighborhood Hits	1291	Shared Neighborhood Hits	19
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ZDH17_MOUSE
NC score	0.008421 (rank : 93)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	96	Target Neighborhood Hits	328	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ZDH17_HUMAN
NC score	0.008241 (rank : 94)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	96	Target Neighborhood Hits	334	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

RAPH1_HUMAN
NC score	0.007765 (rank : 95)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	96	Target Neighborhood Hits	593	Shared Neighborhood Hits	9
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

FXR2_HUMAN
NC score	0.006931 (rank : 96)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	96	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	P51116, Q8WUM2	Gene names	FXR2
Domain Architecture
Description	Fragile X mental retardation syndrome-related protein 2.

MILK1_HUMAN
NC score	0.006066 (rank : 97)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	96	Target Neighborhood Hits	427	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

F262_HUMAN
NC score	0.006044 (rank : 98)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	96	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	O60825, O60824, Q9H3P1	Gene names	PFKFB2
Domain Architecture
Description	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (6PF-2-K/Fru- 2,6-P2ASE heart-type isozyme) (PFK-2/FBPase-2) [Includes: 6- phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)].

MLL3_HUMAN
NC score	0.005024 (rank : 99)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	96	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RHG12_HUMAN
NC score	0.004816 (rank : 100)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	96	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

SI1L1_MOUSE
NC score	0.004255 (rank : 101)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	96	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

VATA1_HUMAN
NC score	0.003312 (rank : 102)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	96	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	P38606, Q96DY6, Q9UHY3	Gene names	ATP6V1A, ATP6A1, ATP6V1A1, VPP2
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1) (Isoform VA68).

KIF12_MOUSE
NC score	0.003115 (rank : 103)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	96	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D2Z8, O35061	Gene names	Kif12
Domain Architecture
Description	Kinesin-like protein KIF12.

MAGC1_HUMAN
NC score	0.002911 (rank : 104)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	96	Target Neighborhood Hits	431	Shared Neighborhood Hits	9
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

NRP2_HUMAN
NC score	0.002252 (rank : 105)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	96	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP1_MOUSE
NC score	0.002162 (rank : 106)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	96	Target Neighborhood Hits	120	Shared Neighborhood Hits	3
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

LAP2_MOUSE
NC score	0.001869 (rank : 107)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	96	Target Neighborhood Hits	482	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TH2, Q8BQ14, Q8CE41, Q8K171, Q99JU3, Q9JI47	Gene names	Erbb2ip, Erbin, Kiaa1225, Lap2
Domain Architecture	No domain graphic available
Description	Protein LAP2 (Erbb2-interacting protein) (Erbin) (Densin-180-like protein).

SNTG2_MOUSE
NC score	0.000585 (rank : 108)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	96	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q925E0	Gene names	Sntg2
Domain Architecture
Description	Gamma-2-syntrophin (G2SYN) (Syntrophin 5) (SYN5).

RRBP1_HUMAN
NC score	-0.002315 (rank : 109)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	96	Target Neighborhood Hits	1306	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

KLF2_HUMAN
NC score	-0.002584 (rank : 110)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	96	Target Neighborhood Hits	755	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y5W3, Q9UJS5, Q9UKR6	Gene names	KLF2, LKLF
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

KLF2_MOUSE
NC score	-0.003408 (rank : 111)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	96	Target Neighborhood Hits	738	Shared Neighborhood Hits	5
SwissProt Accessions	Q60843	Gene names	Klf2, Lklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 2 (Lung krueppel-like factor).

RRBP1_MOUSE
NC score	-0.003451 (rank : 112)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	96	Target Neighborhood Hits	1650	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

MINK1_MOUSE
NC score	-0.003534 (rank : 113)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	96	Target Neighborhood Hits	1451	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

ALK_MOUSE
NC score	-0.003778 (rank : 114)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	96	Target Neighborhood Hits	811	Shared Neighborhood Hits	8
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

WNK1_MOUSE
NC score	-0.003849 (rank : 115)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	96	Target Neighborhood Hits	1179	Shared Neighborhood Hits	16
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

WNK4_MOUSE
NC score	-0.004282 (rank : 116)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	96	Target Neighborhood Hits	961	Shared Neighborhood Hits	9
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

M3K10_HUMAN
NC score	-0.004798 (rank : 117)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	96	Target Neighborhood Hits	1071	Shared Neighborhood Hits	9
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

SNRK_HUMAN
NC score	-0.005330 (rank : 118)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	96	Target Neighborhood Hits	855	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRH2, Q14706, Q68D15, Q6IQ46, Q9NXI7	Gene names	SNRK, KIAA0096, SNFRK
Domain Architecture	No domain graphic available
Description	SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1- related kinase).

MK15_HUMAN
NC score	-0.005337 (rank : 119)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	96	Target Neighborhood Hits	1038	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TD08, Q2TCF9, Q8N362	Gene names	MAPK15, ERK8
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase 15 (EC 2.7.11.24) (Extracellular signal-regulated kinase 8).