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Network neighborhood for query Sequence : SI1L1_MOUSE

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SI1L1_MOUSE
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SI1L1_HUMAN
θ value	0 (rank : 1)	NC score	0.994143 (rank : 2)
Query Neighborhood Hits	189	Target Neighborhood Hits	162	Shared Neighborhood Hits	113
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	189	Target Neighborhood Hits	189	Shared Neighborhood Hits	189
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SI1L2_HUMAN
θ value	0 (rank : 3)	NC score	0.974679 (rank : 4)
Query Neighborhood Hits	189	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
θ value	0 (rank : 4)	NC score	0.975455 (rank : 3)
Query Neighborhood Hits	189	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L3_HUMAN
θ value	0 (rank : 5)	NC score	0.952997 (rank : 5)
Query Neighborhood Hits	189	Target Neighborhood Hits	305	Shared Neighborhood Hits	50
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SIPA1_HUMAN
θ value	1.90044e-183 (rank : 6)	NC score	0.928025 (rank : 7)
Query Neighborhood Hits	189	Target Neighborhood Hits	250	Shared Neighborhood Hits	50
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SIPA1_MOUSE
θ value	2.03516e-177 (rank : 7)	NC score	0.937806 (rank : 6)
Query Neighborhood Hits	189	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

RGP2_HUMAN
θ value	5.54529e-58 (rank : 8)	NC score	0.882084 (rank : 8)
Query Neighborhood Hits	189	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

GRIPE_HUMAN
θ value	7.09661e-13 (rank : 9)	NC score	0.456969 (rank : 9)
Query Neighborhood Hits	189	Target Neighborhood Hits	69	Shared Neighborhood Hits	16
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
θ value	6.00763e-12 (rank : 10)	NC score	0.444570 (rank : 10)
Query Neighborhood Hits	189	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TSC2_HUMAN
θ value	2.52405e-10 (rank : 11)	NC score	0.431390 (rank : 11)
Query Neighborhood Hits	189	Target Neighborhood Hits	59	Shared Neighborhood Hits	16
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TSC2_MOUSE
θ value	1.06045e-08 (rank : 12)	NC score	0.409614 (rank : 12)
Query Neighborhood Hits	189	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

SHAN1_HUMAN
θ value	0.00035302 (rank : 13)	NC score	0.100544 (rank : 24)
Query Neighborhood Hits	189	Target Neighborhood Hits	1041	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

HOME2_MOUSE
θ value	0.00102713 (rank : 14)	NC score	0.067584 (rank : 35)
Query Neighborhood Hits	189	Target Neighborhood Hits	882	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

SHAN2_HUMAN
θ value	0.00390308 (rank : 15)	NC score	0.147314 (rank : 13)
Query Neighborhood Hits	189	Target Neighborhood Hits	346	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

PARD3_HUMAN
θ value	0.0113563 (rank : 16)	NC score	0.081130 (rank : 29)
Query Neighborhood Hits	189	Target Neighborhood Hits	312	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

SHAN2_MOUSE
θ value	0.0148317 (rank : 17)	NC score	0.133426 (rank : 17)
Query Neighborhood Hits	189	Target Neighborhood Hits	446	Shared Neighborhood Hits	42
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

APBA2_HUMAN
θ value	0.0330416 (rank : 18)	NC score	0.136038 (rank : 15)
Query Neighborhood Hits	189	Target Neighborhood Hits	220	Shared Neighborhood Hits	43
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.0330416 (rank : 19)	NC score	0.136099 (rank : 14)
Query Neighborhood Hits	189	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

KCNB2_HUMAN
θ value	0.0330416 (rank : 20)	NC score	0.020748 (rank : 147)
Query Neighborhood Hits	189	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

APBA1_HUMAN
θ value	0.0736092 (rank : 21)	NC score	0.120983 (rank : 18)
Query Neighborhood Hits	189	Target Neighborhood Hits	325	Shared Neighborhood Hits	46
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CCDC6_HUMAN
θ value	0.0736092 (rank : 22)	NC score	0.068161 (rank : 33)
Query Neighborhood Hits	189	Target Neighborhood Hits	723	Shared Neighborhood Hits	76
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

FILA_HUMAN
θ value	0.0736092 (rank : 23)	NC score	0.040585 (rank : 84)
Query Neighborhood Hits	189	Target Neighborhood Hits	685	Shared Neighborhood Hits	24
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

NHERF_HUMAN
θ value	0.0736092 (rank : 24)	NC score	0.119865 (rank : 20)
Query Neighborhood Hits	189	Target Neighborhood Hits	190	Shared Neighborhood Hits	42
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

APBA3_MOUSE
θ value	0.0961366 (rank : 25)	NC score	0.134746 (rank : 16)
Query Neighborhood Hits	189	Target Neighborhood Hits	174	Shared Neighborhood Hits	41
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ARHGB_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.072361 (rank : 31)
Query Neighborhood Hits	189	Target Neighborhood Hits	375	Shared Neighborhood Hits	52
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

NHERF_MOUSE
θ value	0.125558 (rank : 27)	NC score	0.112772 (rank : 21)
Query Neighborhood Hits	189	Target Neighborhood Hits	195	Shared Neighborhood Hits	42
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

SNIP_MOUSE
θ value	0.125558 (rank : 28)	NC score	0.057443 (rank : 42)
Query Neighborhood Hits	189	Target Neighborhood Hits	319	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

EEA1_MOUSE
θ value	0.163984 (rank : 29)	NC score	0.049498 (rank : 59)
Query Neighborhood Hits	189	Target Neighborhood Hits	1637	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

PARD3_MOUSE
θ value	0.163984 (rank : 30)	NC score	0.087620 (rank : 27)
Query Neighborhood Hits	189	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

PDZD3_MOUSE
θ value	0.163984 (rank : 31)	NC score	0.100404 (rank : 25)
Query Neighborhood Hits	189	Target Neighborhood Hits	171	Shared Neighborhood Hits	40
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

THAP6_HUMAN
θ value	0.163984 (rank : 32)	NC score	0.054225 (rank : 45)
Query Neighborhood Hits	189	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TBB0	Gene names	THAP6
Domain Architecture
Description	THAP domain-containing protein 6.

APBA3_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.120198 (rank : 19)
Query Neighborhood Hits	189	Target Neighborhood Hits	201	Shared Neighborhood Hits	41
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

BPAEA_MOUSE
θ value	0.21417 (rank : 34)	NC score	0.043128 (rank : 72)
Query Neighborhood Hits	189	Target Neighborhood Hits	1480	Shared Neighborhood Hits	93
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TPR_HUMAN
θ value	0.21417 (rank : 35)	NC score	0.049547 (rank : 58)
Query Neighborhood Hits	189	Target Neighborhood Hits	1921	Shared Neighborhood Hits	105
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

HMMR_HUMAN
θ value	0.279714 (rank : 36)	NC score	0.046786 (rank : 62)
Query Neighborhood Hits	189	Target Neighborhood Hits	1082	Shared Neighborhood Hits	86
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

OXR1_HUMAN
θ value	0.279714 (rank : 37)	NC score	0.029271 (rank : 124)
Query Neighborhood Hits	189	Target Neighborhood Hits	282	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

USH1C_HUMAN
θ value	0.279714 (rank : 38)	NC score	0.100849 (rank : 23)
Query Neighborhood Hits	189	Target Neighborhood Hits	327	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	0.279714 (rank : 39)	NC score	0.102932 (rank : 22)
Query Neighborhood Hits	189	Target Neighborhood Hits	557	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

GCC2_HUMAN
θ value	0.365318 (rank : 40)	NC score	0.051210 (rank : 50)
Query Neighborhood Hits	189	Target Neighborhood Hits	1558	Shared Neighborhood Hits	93
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGA4_HUMAN
θ value	0.365318 (rank : 41)	NC score	0.050018 (rank : 57)
Query Neighborhood Hits	189	Target Neighborhood Hits	2034	Shared Neighborhood Hits	98
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RBP24_HUMAN
θ value	0.365318 (rank : 42)	NC score	0.050920 (rank : 52)
Query Neighborhood Hits	189	Target Neighborhood Hits	1559	Shared Neighborhood Hits	93
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

PKHG1_HUMAN
θ value	0.47712 (rank : 43)	NC score	0.023266 (rank : 141)
Query Neighborhood Hits	189	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

DOCK4_HUMAN
θ value	0.62314 (rank : 44)	NC score	0.025571 (rank : 135)
Query Neighborhood Hits	189	Target Neighborhood Hits	237	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	0.62314 (rank : 45)	NC score	0.028670 (rank : 125)
Query Neighborhood Hits	189	Target Neighborhood Hits	210	Shared Neighborhood Hits	12
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

HOME2_HUMAN
θ value	0.62314 (rank : 46)	NC score	0.050347 (rank : 54)
Query Neighborhood Hits	189	Target Neighborhood Hits	532	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

RUFY1_MOUSE
θ value	0.62314 (rank : 47)	NC score	0.057704 (rank : 41)
Query Neighborhood Hits	189	Target Neighborhood Hits	765	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

PEPL_MOUSE
θ value	0.813845 (rank : 48)	NC score	0.051052 (rank : 51)
Query Neighborhood Hits	189	Target Neighborhood Hits	1105	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RAI14_MOUSE
θ value	0.813845 (rank : 49)	NC score	0.032728 (rank : 116)
Query Neighborhood Hits	189	Target Neighborhood Hits	1505	Shared Neighborhood Hits	93
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CENPE_HUMAN
θ value	1.06291 (rank : 50)	NC score	0.037590 (rank : 104)
Query Neighborhood Hits	189	Target Neighborhood Hits	2060	Shared Neighborhood Hits	100
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

NHRF2_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.084078 (rank : 28)
Query Neighborhood Hits	189	Target Neighborhood Hits	194	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

OPTN_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.039593 (rank : 92)
Query Neighborhood Hits	189	Target Neighborhood Hits	1120	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

TNIP3_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.050281 (rank : 55)
Query Neighborhood Hits	189	Target Neighborhood Hits	511	Shared Neighborhood Hits	64
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

CCD93_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.042031 (rank : 76)
Query Neighborhood Hits	189	Target Neighborhood Hits	600	Shared Neighborhood Hits	69
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CK5P2_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.048412 (rank : 60)
Query Neighborhood Hits	189	Target Neighborhood Hits	1433	Shared Neighborhood Hits	96
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CK5P2_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.047479 (rank : 61)
Query Neighborhood Hits	189	Target Neighborhood Hits	1151	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

HTF4_MOUSE
θ value	1.38821 (rank : 57)	NC score	0.013001 (rank : 159)
Query Neighborhood Hits	189	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

LZTS1_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.050405 (rank : 53)
Query Neighborhood Hits	189	Target Neighborhood Hits	540	Shared Neighborhood Hits	72
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MAP1B_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.031757 (rank : 118)
Query Neighborhood Hits	189	Target Neighborhood Hits	903	Shared Neighborhood Hits	59
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MPDZ_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.052362 (rank : 46)
Query Neighborhood Hits	189	Target Neighborhood Hits	261	Shared Neighborhood Hits	43
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

NCOR2_MOUSE
θ value	1.38821 (rank : 61)	NC score	0.030125 (rank : 121)
Query Neighborhood Hits	189	Target Neighborhood Hits	790	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PDZ11_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.059091 (rank : 39)
Query Neighborhood Hits	189	Target Neighborhood Hits	160	Shared Neighborhood Hits	34
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	1.38821 (rank : 63)	NC score	0.056689 (rank : 43)
Query Neighborhood Hits	189	Target Neighborhood Hits	154	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

RUFY2_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.052316 (rank : 47)
Query Neighborhood Hits	189	Target Neighborhood Hits	1208	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SMC3_HUMAN
θ value	1.38821 (rank : 65)	NC score	0.041471 (rank : 79)
Query Neighborhood Hits	189	Target Neighborhood Hits	1186	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	1.38821 (rank : 66)	NC score	0.041606 (rank : 78)
Query Neighborhood Hits	189	Target Neighborhood Hits	1187	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

CCDC3_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.034483 (rank : 113)
Query Neighborhood Hits	189	Target Neighborhood Hits	111	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQI4	Gene names	CCDC3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

CCDC3_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.036976 (rank : 106)
Query Neighborhood Hits	189	Target Neighborhood Hits	131	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

HOOK3_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.043748 (rank : 68)
Query Neighborhood Hits	189	Target Neighborhood Hits	1070	Shared Neighborhood Hits	90
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	1.81305 (rank : 70)	NC score	0.043770 (rank : 67)
Query Neighborhood Hits	189	Target Neighborhood Hits	1007	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

MYH7_HUMAN
θ value	1.81305 (rank : 71)	NC score	0.028331 (rank : 126)
Query Neighborhood Hits	189	Target Neighborhood Hits	1559	Shared Neighborhood Hits	86
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NFM_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.026884 (rank : 128)
Query Neighborhood Hits	189	Target Neighborhood Hits	1328	Shared Neighborhood Hits	90
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NFM_MOUSE
θ value	1.81305 (rank : 73)	NC score	0.026569 (rank : 130)
Query Neighborhood Hits	189	Target Neighborhood Hits	1159	Shared Neighborhood Hits	83
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NHRF2_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.089678 (rank : 26)
Query Neighborhood Hits	189	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NIN_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.039246 (rank : 98)
Query Neighborhood Hits	189	Target Neighborhood Hits	1416	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NSDHL_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.022903 (rank : 144)
Query Neighborhood Hits	189	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1J0, O55109	Gene names	Nsdhl
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170).

PININ_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.043405 (rank : 71)
Query Neighborhood Hits	189	Target Neighborhood Hits	753	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	1.81305 (rank : 78)	NC score	0.043771 (rank : 66)
Query Neighborhood Hits	189	Target Neighborhood Hits	777	Shared Neighborhood Hits	76
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RUFY2_MOUSE
θ value	1.81305 (rank : 79)	NC score	0.059393 (rank : 38)
Query Neighborhood Hits	189	Target Neighborhood Hits	820	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SET1A_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.014077 (rank : 158)
Query Neighborhood Hits	189	Target Neighborhood Hits	690	Shared Neighborhood Hits	26
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SMCA2_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.012658 (rank : 160)
Query Neighborhood Hits	189	Target Neighborhood Hits	503	Shared Neighborhood Hits	37
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SNIP_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.039348 (rank : 95)
Query Neighborhood Hits	189	Target Neighborhood Hits	313	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SPTB1_MOUSE
θ value	1.81305 (rank : 83)	NC score	0.021621 (rank : 146)
Query Neighborhood Hits	189	Target Neighborhood Hits	543	Shared Neighborhood Hits	65
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

TLN2_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.020203 (rank : 150)
Query Neighborhood Hits	189	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

APC_MOUSE
θ value	2.36792 (rank : 85)	NC score	0.025740 (rank : 134)
Query Neighborhood Hits	189	Target Neighborhood Hits	441	Shared Neighborhood Hits	46
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CSKP_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.002426 (rank : 185)
Query Neighborhood Hits	189	Target Neighborhood Hits	1022	Shared Neighborhood Hits	34
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

CT112_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.014553 (rank : 157)
Query Neighborhood Hits	189	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MY1, Q5JYB7, Q6P0Y4, Q9BR34, Q9NQF6	Gene names	C20orf112
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112.

DYNA_HUMAN
θ value	2.36792 (rank : 88)	NC score	0.040988 (rank : 81)
Query Neighborhood Hits	189	Target Neighborhood Hits	1194	Shared Neighborhood Hits	82
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.041297 (rank : 80)
Query Neighborhood Hits	189	Target Neighborhood Hits	1084	Shared Neighborhood Hits	78
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

EEA1_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.044962 (rank : 65)
Query Neighborhood Hits	189	Target Neighborhood Hits	1796	Shared Neighborhood Hits	96
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

KS6C1_HUMAN
θ value	2.36792 (rank : 91)	NC score	0.004533 (rank : 179)
Query Neighborhood Hits	189	Target Neighborhood Hits	682	Shared Neighborhood Hits	7
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

LAP4_MOUSE
θ value	2.36792 (rank : 92)	NC score	0.046431 (rank : 63)
Query Neighborhood Hits	189	Target Neighborhood Hits	590	Shared Neighborhood Hits	52
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

PACS1_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.024025 (rank : 137)
Query Neighborhood Hits	189	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PACS1_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.023795 (rank : 140)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PPRB_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.026367 (rank : 131)
Query Neighborhood Hits	189	Target Neighborhood Hits	311	Shared Neighborhood Hits	15
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SH22A_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.015571 (rank : 155)
Query Neighborhood Hits	189	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

STMN1_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.027056 (rank : 127)
Query Neighborhood Hits	189	Target Neighborhood Hits	554	Shared Neighborhood Hits	60
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

TLN2_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.020410 (rank : 149)
Query Neighborhood Hits	189	Target Neighborhood Hits	149	Shared Neighborhood Hits	9
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

CYTSA_HUMAN
θ value	3.0926 (rank : 99)	NC score	0.045539 (rank : 64)
Query Neighborhood Hits	189	Target Neighborhood Hits	1138	Shared Neighborhood Hits	88
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	3.0926 (rank : 100)	NC score	0.043530 (rank : 69)
Query Neighborhood Hits	189	Target Neighborhood Hits	1104	Shared Neighborhood Hits	84
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

LOXL1_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.009877 (rank : 171)
Query Neighborhood Hits	189	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

MAP1B_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.031343 (rank : 120)
Query Neighborhood Hits	189	Target Neighborhood Hits	977	Shared Neighborhood Hits	67
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MPDZ_MOUSE
θ value	3.0926 (rank : 103)	NC score	0.050130 (rank : 56)
Query Neighborhood Hits	189	Target Neighborhood Hits	298	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

MY18A_MOUSE
θ value	3.0926 (rank : 104)	NC score	0.038898 (rank : 99)
Query Neighborhood Hits	189	Target Neighborhood Hits	1989	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYO5C_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.026627 (rank : 129)
Query Neighborhood Hits	189	Target Neighborhood Hits	1206	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NFAT5_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.010745 (rank : 167)
Query Neighborhood Hits	189	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

RHPN2_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.012512 (rank : 161)
Query Neighborhood Hits	189	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

RUFY1_HUMAN
θ value	3.0926 (rank : 108)	NC score	0.059014 (rank : 40)
Query Neighborhood Hits	189	Target Neighborhood Hits	848	Shared Neighborhood Hits	80
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

SEM6A_MOUSE
θ value	3.0926 (rank : 109)	NC score	0.004255 (rank : 180)
Query Neighborhood Hits	189	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

STMN1_MOUSE
θ value	3.0926 (rank : 110)	NC score	0.025843 (rank : 133)
Query Neighborhood Hits	189	Target Neighborhood Hits	560	Shared Neighborhood Hits	61
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

VIME_HUMAN
θ value	3.0926 (rank : 111)	NC score	0.024209 (rank : 136)
Query Neighborhood Hits	189	Target Neighborhood Hits	706	Shared Neighborhood Hits	72
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

BPA1_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.034568 (rank : 112)
Query Neighborhood Hits	189	Target Neighborhood Hits	1477	Shared Neighborhood Hits	89
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCHCR_MOUSE
θ value	4.03905 (rank : 113)	NC score	0.039283 (rank : 97)
Query Neighborhood Hits	189	Target Neighborhood Hits	932	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CENPF_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.036097 (rank : 110)
Query Neighborhood Hits	189	Target Neighborhood Hits	1932	Shared Neighborhood Hits	92
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CING_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.039951 (rank : 89)
Query Neighborhood Hits	189	Target Neighborhood Hits	1275	Shared Neighborhood Hits	91
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CN145_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.043487 (rank : 70)
Query Neighborhood Hits	189	Target Neighborhood Hits	1196	Shared Neighborhood Hits	91
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

LAP4_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.040181 (rank : 87)
Query Neighborhood Hits	189	Target Neighborhood Hits	608	Shared Neighborhood Hits	51
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

OTOF_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.011770 (rank : 163)
Query Neighborhood Hits	189	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

PCNT_MOUSE
θ value	4.03905 (rank : 119)	NC score	0.042273 (rank : 75)
Query Neighborhood Hits	189	Target Neighborhood Hits	1207	Shared Neighborhood Hits	92
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PDZD1_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.077943 (rank : 30)
Query Neighborhood Hits	189	Target Neighborhood Hits	190	Shared Neighborhood Hits	42
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ROCK2_MOUSE
θ value	4.03905 (rank : 121)	NC score	0.016201 (rank : 154)
Query Neighborhood Hits	189	Target Neighborhood Hits	2072	Shared Neighborhood Hits	97
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

SYCP1_MOUSE
θ value	4.03905 (rank : 122)	NC score	0.039417 (rank : 94)
Query Neighborhood Hits	189	Target Neighborhood Hits	1456	Shared Neighborhood Hits	88
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

VAPB_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.039288 (rank : 96)
Query Neighborhood Hits	189	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	O95292, O95293, Q9P0H0	Gene names	VAPB
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B/C (VAMP- associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C).

VIME_MOUSE
θ value	4.03905 (rank : 124)	NC score	0.023845 (rank : 139)
Query Neighborhood Hits	189	Target Neighborhood Hits	716	Shared Neighborhood Hits	74
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

WHRN_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.066595 (rank : 36)
Query Neighborhood Hits	189	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

APC_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.022848 (rank : 145)
Query Neighborhood Hits	189	Target Neighborhood Hits	603	Shared Neighborhood Hits	48
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BMPR2_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.002462 (rank : 184)
Query Neighborhood Hits	189	Target Neighborhood Hits	738	Shared Neighborhood Hits	12
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

CCD91_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.033713 (rank : 114)
Query Neighborhood Hits	189	Target Neighborhood Hits	699	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

ERC2_HUMAN
θ value	5.27518 (rank : 129)	NC score	0.040783 (rank : 83)
Query Neighborhood Hits	189	Target Neighborhood Hits	1156	Shared Neighborhood Hits	85
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

GNAS1_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.003297 (rank : 182)
Query Neighborhood Hits	189	Target Neighborhood Hits	651	Shared Neighborhood Hits	15
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

IFT74_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.038427 (rank : 101)
Query Neighborhood Hits	189	Target Neighborhood Hits	939	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

MAGI1_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.054529 (rank : 44)
Query Neighborhood Hits	189	Target Neighborhood Hits	388	Shared Neighborhood Hits	47
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	5.27518 (rank : 133)	NC score	0.051835 (rank : 49)
Query Neighborhood Hits	189	Target Neighborhood Hits	403	Shared Neighborhood Hits	47
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MY18A_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.036537 (rank : 108)
Query Neighborhood Hits	189	Target Neighborhood Hits	1929	Shared Neighborhood Hits	122
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NCOR2_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.019655 (rank : 151)
Query Neighborhood Hits	189	Target Neighborhood Hits	870	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

ROCK2_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.015280 (rank : 156)
Query Neighborhood Hits	189	Target Neighborhood Hits	2073	Shared Neighborhood Hits	96
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

RPTN_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.010781 (rank : 166)
Query Neighborhood Hits	189	Target Neighborhood Hits	406	Shared Neighborhood Hits	13
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

TAB3_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.025972 (rank : 132)
Query Neighborhood Hits	189	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TAB3_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.023055 (rank : 143)
Query Neighborhood Hits	189	Target Neighborhood Hits	273	Shared Neighborhood Hits	13
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TEX2_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.010620 (rank : 168)
Query Neighborhood Hits	189	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TLN1_MOUSE
θ value	5.27518 (rank : 141)	NC score	0.023215 (rank : 142)
Query Neighborhood Hits	189	Target Neighborhood Hits	213	Shared Neighborhood Hits	18
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

WEE1B_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.001153 (rank : 186)
Query Neighborhood Hits	189	Target Neighborhood Hits	836	Shared Neighborhood Hits	13
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

WHRN_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.068309 (rank : 32)
Query Neighborhood Hits	189	Target Neighborhood Hits	325	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

BSN_MOUSE
θ value	6.88961 (rank : 144)	NC score	0.023985 (rank : 138)
Query Neighborhood Hits	189	Target Neighborhood Hits	2057	Shared Neighborhood Hits	91
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CE290_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.038551 (rank : 100)
Query Neighborhood Hits	189	Target Neighborhood Hits	1553	Shared Neighborhood Hits	92
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CP135_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.039930 (rank : 90)
Query Neighborhood Hits	189	Target Neighborhood Hits	1290	Shared Neighborhood Hits	89
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DCR1A_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.012207 (rank : 162)
Query Neighborhood Hits	189	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

DOCK3_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.016660 (rank : 153)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

FA53C_MOUSE
θ value	6.88961 (rank : 149)	NC score	0.010114 (rank : 170)
Query Neighborhood Hits	189	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BXQ8, Q3U4J2	Gene names	Fam53c
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

GCC1_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.039522 (rank : 93)
Query Neighborhood Hits	189	Target Neighborhood Hits	777	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GOGB1_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.040434 (rank : 86)
Query Neighborhood Hits	189	Target Neighborhood Hits	2297	Shared Neighborhood Hits	99
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

KCNH4_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.003357 (rank : 181)
Query Neighborhood Hits	189	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KIF3A_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.020640 (rank : 148)
Query Neighborhood Hits	189	Target Neighborhood Hits	715	Shared Neighborhood Hits	75
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

LDLR_MOUSE
θ value	6.88961 (rank : 154)	NC score	0.000751 (rank : 187)
Query Neighborhood Hits	189	Target Neighborhood Hits	382	Shared Neighborhood Hits	3
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MACOI_MOUSE
θ value	6.88961 (rank : 155)	NC score	0.042411 (rank : 74)
Query Neighborhood Hits	189	Target Neighborhood Hits	620	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MYCD_MOUSE
θ value	6.88961 (rank : 156)	NC score	0.007857 (rank : 174)
Query Neighborhood Hits	189	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

MYO15_MOUSE
θ value	6.88961 (rank : 157)	NC score	0.008184 (rank : 173)
Query Neighborhood Hits	189	Target Neighborhood Hits	467	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NU214_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.018200 (rank : 152)
Query Neighborhood Hits	189	Target Neighborhood Hits	657	Shared Neighborhood Hits	38
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

OBSCN_HUMAN
θ value	6.88961 (rank : 159)	NC score	-0.000778 (rank : 189)
Query Neighborhood Hits	189	Target Neighborhood Hits	1931	Shared Neighborhood Hits	25
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PDZD1_MOUSE
θ value	6.88961 (rank : 160)	NC score	0.060964 (rank : 37)
Query Neighborhood Hits	189	Target Neighborhood Hits	191	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

POPD1_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.008534 (rank : 172)
Query Neighborhood Hits	189	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE79, Q8IWC6, Q9HBV0, Q9UNG6	Gene names	BVES, POP1, POPDC1
Domain Architecture
Description	Blood vessel epicardial substance (hBVES) (Popeye domain-containing protein 1) (Popeye protein 1).

PXDC1_MOUSE
θ value	6.88961 (rank : 162)	NC score	0.007716 (rank : 175)
Query Neighborhood Hits	189	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZV7, Q8BM20, Q9CWV5	Gene names	Plxdc1, Tem7
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 1 precursor (Tumor endothelial marker 7).

RILP_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.029492 (rank : 123)
Query Neighborhood Hits	189	Target Neighborhood Hits	257	Shared Neighborhood Hits	42
SwissProt Accessions	Q5ND29, Q80WB8, Q8CHY9	Gene names	Rilp
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

TRIPB_HUMAN
θ value	6.88961 (rank : 164)	NC score	0.039622 (rank : 91)
Query Neighborhood Hits	189	Target Neighborhood Hits	1587	Shared Neighborhood Hits	91
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TUFT1_HUMAN
θ value	6.88961 (rank : 165)	NC score	0.040930 (rank : 82)
Query Neighborhood Hits	189	Target Neighborhood Hits	686	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

VAPB_MOUSE
θ value	6.88961 (rank : 166)	NC score	0.029945 (rank : 122)
Query Neighborhood Hits	189	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY76	Gene names	Vapb
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B (VAMP- associated protein B) (VAMP-associated protein 33b) (VAMP-B) (VAP-B).

ZCH10_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.042894 (rank : 73)
Query Neighborhood Hits	189	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

BICD2_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.033334 (rank : 115)
Query Neighborhood Hits	189	Target Neighborhood Hits	856	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.034689 (rank : 111)
Query Neighborhood Hits	189	Target Neighborhood Hits	864	Shared Neighborhood Hits	79
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BMPR2_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.000400 (rank : 188)
Query Neighborhood Hits	189	Target Neighborhood Hits	736	Shared Neighborhood Hits	9
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

CN145_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.041938 (rank : 77)
Query Neighborhood Hits	189	Target Neighborhood Hits	916	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CSPG2_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.002629 (rank : 183)
Query Neighborhood Hits	189	Target Neighborhood Hits	681	Shared Neighborhood Hits	10
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

ERC2_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.040142 (rank : 88)
Query Neighborhood Hits	189	Target Neighborhood Hits	1166	Shared Neighborhood Hits	85
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

GAS8_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.036732 (rank : 107)
Query Neighborhood Hits	189	Target Neighborhood Hits	819	Shared Neighborhood Hits	78
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GOPC_HUMAN
θ value	8.99809 (rank : 175)	NC score	0.040541 (rank : 85)
Query Neighborhood Hits	189	Target Neighborhood Hits	377	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GP149_MOUSE
θ value	8.99809 (rank : 176)	NC score	0.007534 (rank : 176)
Query Neighborhood Hits	189	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UVY1, Q3TMB1, Q80T52, Q8BXA3, Q8BZC0	Gene names	Gpr149, Pgr10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

IFT74_HUMAN
θ value	8.99809 (rank : 177)	NC score	0.037808 (rank : 103)
Query Neighborhood Hits	189	Target Neighborhood Hits	949	Shared Neighborhood Hits	77
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

INSRR_MOUSE
θ value	8.99809 (rank : 178)	NC score	-0.002429 (rank : 190)
Query Neighborhood Hits	189	Target Neighborhood Hits	961	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

NPBL_MOUSE
θ value	8.99809 (rank : 179)	NC score	0.011003 (rank : 165)
Query Neighborhood Hits	189	Target Neighborhood Hits	1041	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PDZD3_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.067684 (rank : 34)
Query Neighborhood Hits	189	Target Neighborhood Hits	180	Shared Neighborhood Hits	41
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PTN13_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.032570 (rank : 117)
Query Neighborhood Hits	189	Target Neighborhood Hits	471	Shared Neighborhood Hits	55
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

RB6I2_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.036523 (rank : 109)
Query Neighborhood Hits	189	Target Neighborhood Hits	1584	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	8.99809 (rank : 183)	NC score	0.037310 (rank : 105)
Query Neighborhood Hits	189	Target Neighborhood Hits	1433	Shared Neighborhood Hits	88
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RIMB1_MOUSE
θ value	8.99809 (rank : 184)	NC score	0.031642 (rank : 119)
Query Neighborhood Hits	189	Target Neighborhood Hits	1376	Shared Neighborhood Hits	90
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RPGF6_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.037871 (rank : 102)
Query Neighborhood Hits	189	Target Neighborhood Hits	266	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SCYBG_MOUSE
θ value	8.99809 (rank : 186)	NC score	0.011104 (rank : 164)
Query Neighborhood Hits	189	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BSU2, Q8VE25, Q9EPB3	Gene names	Cxcl16, Srpsox
Domain Architecture	No domain graphic available
Description	Small inducible cytokine B16 precursor (Transmembrane chemokine CXCL16) (SR-PSOX) (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein).

SPY2_HUMAN
θ value	8.99809 (rank : 187)	NC score	0.005144 (rank : 177)
Query Neighborhood Hits	189	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

TULP2_HUMAN
θ value	8.99809 (rank : 188)	NC score	0.010585 (rank : 169)
Query Neighborhood Hits	189	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O00295	Gene names	TULP2
Domain Architecture
Description	Tubby-related protein 2 (Tubby-like protein 2).

VMDL3_HUMAN
θ value	8.99809 (rank : 189)	NC score	0.004703 (rank : 178)
Query Neighborhood Hits	189	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N1M1, Q8N356, Q8NFT9, Q9BR80	Gene names	VMD2L3
Domain Architecture
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

MYOC_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.052005 (rank : 48)
Query Neighborhood Hits	189	Target Neighborhood Hits	489	Shared Neighborhood Hits	63
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

Hits sorted by NC score

SI1L1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	189	Target Neighborhood Hits	189	Shared Neighborhood Hits	189
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SI1L1_HUMAN
NC score	0.994143 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	189	Target Neighborhood Hits	162	Shared Neighborhood Hits	113
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L2_MOUSE
NC score	0.975455 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	189	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_HUMAN
NC score	0.974679 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	189	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L3_HUMAN
NC score	0.952997 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	189	Target Neighborhood Hits	305	Shared Neighborhood Hits	50
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SIPA1_MOUSE
NC score	0.937806 (rank : 6)	θ value	2.03516e-177 (rank : 7)
Query Neighborhood Hits	189	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SIPA1_HUMAN
NC score	0.928025 (rank : 7)	θ value	1.90044e-183 (rank : 6)
Query Neighborhood Hits	189	Target Neighborhood Hits	250	Shared Neighborhood Hits	50
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

RGP2_HUMAN
NC score	0.882084 (rank : 8)	θ value	5.54529e-58 (rank : 8)
Query Neighborhood Hits	189	Target Neighborhood Hits	60	Shared Neighborhood Hits	14
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

GRIPE_HUMAN
NC score	0.456969 (rank : 9)	θ value	7.09661e-13 (rank : 9)
Query Neighborhood Hits	189	Target Neighborhood Hits	69	Shared Neighborhood Hits	16
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
NC score	0.444570 (rank : 10)	θ value	6.00763e-12 (rank : 10)
Query Neighborhood Hits	189	Target Neighborhood Hits	70	Shared Neighborhood Hits	14
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TSC2_HUMAN
NC score	0.431390 (rank : 11)	θ value	2.52405e-10 (rank : 11)
Query Neighborhood Hits	189	Target Neighborhood Hits	59	Shared Neighborhood Hits	16
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TSC2_MOUSE
NC score	0.409614 (rank : 12)	θ value	1.06045e-08 (rank : 12)
Query Neighborhood Hits	189	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

SHAN2_HUMAN
NC score	0.147314 (rank : 13)	θ value	0.00390308 (rank : 15)
Query Neighborhood Hits	189	Target Neighborhood Hits	346	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

APBA2_MOUSE
NC score	0.136099 (rank : 14)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	189	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_HUMAN
NC score	0.136038 (rank : 15)	θ value	0.0330416 (rank : 18)
Query Neighborhood Hits	189	Target Neighborhood Hits	220	Shared Neighborhood Hits	43
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_MOUSE
NC score	0.134746 (rank : 16)	θ value	0.0961366 (rank : 25)
Query Neighborhood Hits	189	Target Neighborhood Hits	174	Shared Neighborhood Hits	41
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SHAN2_MOUSE
NC score	0.133426 (rank : 17)	θ value	0.0148317 (rank : 17)
Query Neighborhood Hits	189	Target Neighborhood Hits	446	Shared Neighborhood Hits	42
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

APBA1_HUMAN
NC score	0.120983 (rank : 18)	θ value	0.0736092 (rank : 21)
Query Neighborhood Hits	189	Target Neighborhood Hits	325	Shared Neighborhood Hits	46
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

APBA3_HUMAN
NC score	0.120198 (rank : 19)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	189	Target Neighborhood Hits	201	Shared Neighborhood Hits	41
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

NHERF_HUMAN
NC score	0.119865 (rank : 20)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	189	Target Neighborhood Hits	190	Shared Neighborhood Hits	42
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

NHERF_MOUSE
NC score	0.112772 (rank : 21)	θ value	0.125558 (rank : 27)
Query Neighborhood Hits	189	Target Neighborhood Hits	195	Shared Neighborhood Hits	42
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

USH1C_MOUSE
NC score	0.102932 (rank : 22)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	189	Target Neighborhood Hits	557	Shared Neighborhood Hits	83
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

USH1C_HUMAN
NC score	0.100849 (rank : 23)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	189	Target Neighborhood Hits	327	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

SHAN1_HUMAN
NC score	0.100544 (rank : 24)	θ value	0.00035302 (rank : 13)
Query Neighborhood Hits	189	Target Neighborhood Hits	1041	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PDZD3_MOUSE
NC score	0.100404 (rank : 25)	θ value	0.163984 (rank : 31)
Query Neighborhood Hits	189	Target Neighborhood Hits	171	Shared Neighborhood Hits	40
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

NHRF2_HUMAN
NC score	0.089678 (rank : 26)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	189	Target Neighborhood Hits	197	Shared Neighborhood Hits	39
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PARD3_MOUSE
NC score	0.087620 (rank : 27)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	189	Target Neighborhood Hits	290	Shared Neighborhood Hits	50
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

NHRF2_MOUSE
NC score	0.084078 (rank : 28)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	189	Target Neighborhood Hits	194	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PARD3_HUMAN
NC score	0.081130 (rank : 29)	θ value	0.0113563 (rank : 16)
Query Neighborhood Hits	189	Target Neighborhood Hits	312	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PDZD1_HUMAN
NC score	0.077943 (rank : 30)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	189	Target Neighborhood Hits	190	Shared Neighborhood Hits	42
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ARHGB_HUMAN
NC score	0.072361 (rank : 31)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	189	Target Neighborhood Hits	375	Shared Neighborhood Hits	52
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

WHRN_HUMAN
NC score	0.068309 (rank : 32)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	189	Target Neighborhood Hits	325	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

CCDC6_HUMAN
NC score	0.068161 (rank : 33)	θ value	0.0736092 (rank : 22)
Query Neighborhood Hits	189	Target Neighborhood Hits	723	Shared Neighborhood Hits	76
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

PDZD3_HUMAN
NC score	0.067684 (rank : 34)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	189	Target Neighborhood Hits	180	Shared Neighborhood Hits	41
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

HOME2_MOUSE
NC score	0.067584 (rank : 35)	θ value	0.00102713 (rank : 14)
Query Neighborhood Hits	189	Target Neighborhood Hits	882	Shared Neighborhood Hits	78
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

WHRN_MOUSE
NC score	0.066595 (rank : 36)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	189	Target Neighborhood Hits	412	Shared Neighborhood Hits	45
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZD1_MOUSE
NC score	0.060964 (rank : 37)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	189	Target Neighborhood Hits	191	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

RUFY2_MOUSE
NC score	0.059393 (rank : 38)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	189	Target Neighborhood Hits	820	Shared Neighborhood Hits	78
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

PDZ11_HUMAN
NC score	0.059091 (rank : 39)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	189	Target Neighborhood Hits	160	Shared Neighborhood Hits	34
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

RUFY1_HUMAN
NC score	0.059014 (rank : 40)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	189	Target Neighborhood Hits	848	Shared Neighborhood Hits	80
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY1_MOUSE
NC score	0.057704 (rank : 41)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	189	Target Neighborhood Hits	765	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

SNIP_MOUSE
NC score	0.057443 (rank : 42)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	189	Target Neighborhood Hits	319	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

PDZ11_MOUSE
NC score	0.056689 (rank : 43)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	189	Target Neighborhood Hits	154	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

MAGI1_HUMAN
NC score	0.054529 (rank : 44)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	189	Target Neighborhood Hits	388	Shared Neighborhood Hits	47
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

THAP6_HUMAN
NC score	0.054225 (rank : 45)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	189	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TBB0	Gene names	THAP6
Domain Architecture
Description	THAP domain-containing protein 6.

MPDZ_HUMAN
NC score	0.052362 (rank : 46)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	189	Target Neighborhood Hits	261	Shared Neighborhood Hits	43
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

RUFY2_HUMAN
NC score	0.052316 (rank : 47)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	189	Target Neighborhood Hits	1208	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

MYOC_HUMAN
NC score	0.052005 (rank : 48)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	189	Target Neighborhood Hits	489	Shared Neighborhood Hits	63
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

MAGI1_MOUSE
NC score	0.051835 (rank : 49)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	189	Target Neighborhood Hits	403	Shared Neighborhood Hits	47
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

GCC2_HUMAN
NC score	0.051210 (rank : 50)	θ value	0.365318 (rank : 40)
Query Neighborhood Hits	189	Target Neighborhood Hits	1558	Shared Neighborhood Hits	93
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

PEPL_MOUSE
NC score	0.051052 (rank : 51)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	189	Target Neighborhood Hits	1105	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RBP24_HUMAN
NC score	0.050920 (rank : 52)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	189	Target Neighborhood Hits	1559	Shared Neighborhood Hits	93
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

LZTS1_MOUSE
NC score	0.050405 (rank : 53)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	189	Target Neighborhood Hits	540	Shared Neighborhood Hits	72
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

HOME2_HUMAN
NC score	0.050347 (rank : 54)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	189	Target Neighborhood Hits	532	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

TNIP3_HUMAN
NC score	0.050281 (rank : 55)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	189	Target Neighborhood Hits	511	Shared Neighborhood Hits	64
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

MPDZ_MOUSE
NC score	0.050130 (rank : 56)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	189	Target Neighborhood Hits	298	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

GOGA4_HUMAN
NC score	0.050018 (rank : 57)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	189	Target Neighborhood Hits	2034	Shared Neighborhood Hits	98
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

TPR_HUMAN
NC score	0.049547 (rank : 58)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	189	Target Neighborhood Hits	1921	Shared Neighborhood Hits	105
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

EEA1_MOUSE
NC score	0.049498 (rank : 59)	θ value	0.163984 (rank : 29)
Query Neighborhood Hits	189	Target Neighborhood Hits	1637	Shared Neighborhood Hits	92
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

CK5P2_HUMAN
NC score	0.048412 (rank : 60)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	189	Target Neighborhood Hits	1433	Shared Neighborhood Hits	96
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CK5P2_MOUSE
NC score	0.047479 (rank : 61)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	189	Target Neighborhood Hits	1151	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

HMMR_HUMAN
NC score	0.046786 (rank : 62)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	189	Target Neighborhood Hits	1082	Shared Neighborhood Hits	86
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

LAP4_MOUSE
NC score	0.046431 (rank : 63)	θ value	2.36792 (rank : 92)
Query Neighborhood Hits	189	Target Neighborhood Hits	590	Shared Neighborhood Hits	52
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

CYTSA_HUMAN
NC score	0.045539 (rank : 64)	θ value	3.0926 (rank : 99)
Query Neighborhood Hits	189	Target Neighborhood Hits	1138	Shared Neighborhood Hits	88
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

EEA1_HUMAN
NC score	0.044962 (rank : 65)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	189	Target Neighborhood Hits	1796	Shared Neighborhood Hits	96
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

PININ_MOUSE
NC score	0.043771 (rank : 66)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	189	Target Neighborhood Hits	777	Shared Neighborhood Hits	76
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

HOOK3_MOUSE
NC score	0.043770 (rank : 67)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	189	Target Neighborhood Hits	1007	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

HOOK3_HUMAN
NC score	0.043748 (rank : 68)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	189	Target Neighborhood Hits	1070	Shared Neighborhood Hits	90
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

CYTSA_MOUSE
NC score	0.043530 (rank : 69)	θ value	3.0926 (rank : 100)
Query Neighborhood Hits	189	Target Neighborhood Hits	1104	Shared Neighborhood Hits	84
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

CN145_HUMAN
NC score	0.043487 (rank : 70)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	189	Target Neighborhood Hits	1196	Shared Neighborhood Hits	91
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

PININ_HUMAN
NC score	0.043405 (rank : 71)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	189	Target Neighborhood Hits	753	Shared Neighborhood Hits	73
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

BPAEA_MOUSE
NC score	0.043128 (rank : 72)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	189	Target Neighborhood Hits	1480	Shared Neighborhood Hits	93
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ZCH10_HUMAN
NC score	0.042894 (rank : 73)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	189	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

MACOI_MOUSE
NC score	0.042411 (rank : 74)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	189	Target Neighborhood Hits	620	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

PCNT_MOUSE
NC score	0.042273 (rank : 75)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	189	Target Neighborhood Hits	1207	Shared Neighborhood Hits	92
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

CCD93_HUMAN
NC score	0.042031 (rank : 76)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	189	Target Neighborhood Hits	600	Shared Neighborhood Hits	69
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CN145_MOUSE
NC score	0.041938 (rank : 77)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	189	Target Neighborhood Hits	916	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

SMC3_MOUSE
NC score	0.041606 (rank : 78)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	189	Target Neighborhood Hits	1187	Shared Neighborhood Hits	82
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.041471 (rank : 79)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	189	Target Neighborhood Hits	1186	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

DYNA_MOUSE
NC score	0.041297 (rank : 80)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	189	Target Neighborhood Hits	1084	Shared Neighborhood Hits	78
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

DYNA_HUMAN
NC score	0.040988 (rank : 81)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	189	Target Neighborhood Hits	1194	Shared Neighborhood Hits	82
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

TUFT1_HUMAN
NC score	0.040930 (rank : 82)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	189	Target Neighborhood Hits	686	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

ERC2_HUMAN
NC score	0.040783 (rank : 83)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	189	Target Neighborhood Hits	1156	Shared Neighborhood Hits	85
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

FILA_HUMAN
NC score	0.040585 (rank : 84)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	189	Target Neighborhood Hits	685	Shared Neighborhood Hits	24
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GOPC_HUMAN
NC score	0.040541 (rank : 85)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	189	Target Neighborhood Hits	377	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HD26, Q59FS4, Q969U8	Gene names	GOPC, CAL, FIG
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST) (CFTR-associated ligand) (Fused in glioblastoma).

GOGB1_HUMAN
NC score	0.040434 (rank : 86)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	189	Target Neighborhood Hits	2297	Shared Neighborhood Hits	99
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LAP4_HUMAN
NC score	0.040181 (rank : 87)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	189	Target Neighborhood Hits	608	Shared Neighborhood Hits	51
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

ERC2_MOUSE
NC score	0.040142 (rank : 88)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	189	Target Neighborhood Hits	1166	Shared Neighborhood Hits	85
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

CING_HUMAN
NC score	0.039951 (rank : 89)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	189	Target Neighborhood Hits	1275	Shared Neighborhood Hits	91
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CP135_HUMAN
NC score	0.039930 (rank : 90)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	189	Target Neighborhood Hits	1290	Shared Neighborhood Hits	89
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

TRIPB_HUMAN
NC score	0.039622 (rank : 91)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	189	Target Neighborhood Hits	1587	Shared Neighborhood Hits	91
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

OPTN_MOUSE
NC score	0.039593 (rank : 92)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	189	Target Neighborhood Hits	1120	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

GCC1_MOUSE
NC score	0.039522 (rank : 93)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	189	Target Neighborhood Hits	777	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

SYCP1_MOUSE
NC score	0.039417 (rank : 94)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	189	Target Neighborhood Hits	1456	Shared Neighborhood Hits	88
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SNIP_HUMAN
NC score	0.039348 (rank : 95)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	189	Target Neighborhood Hits	313	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

VAPB_HUMAN
NC score	0.039288 (rank : 96)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	189	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	O95292, O95293, Q9P0H0	Gene names	VAPB
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B/C (VAMP- associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C).

CCHCR_MOUSE
NC score	0.039283 (rank : 97)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	189	Target Neighborhood Hits	932	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

NIN_HUMAN
NC score	0.039246 (rank : 98)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	189	Target Neighborhood Hits	1416	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

MY18A_MOUSE
NC score	0.038898 (rank : 99)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	189	Target Neighborhood Hits	1989	Shared Neighborhood Hits	123
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CE290_HUMAN
NC score	0.038551 (rank : 100)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	189	Target Neighborhood Hits	1553	Shared Neighborhood Hits	92
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

IFT74_MOUSE
NC score	0.038427 (rank : 101)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	189	Target Neighborhood Hits	939	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

RPGF6_HUMAN
NC score	0.037871 (rank : 102)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	189	Target Neighborhood Hits	266	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

IFT74_HUMAN
NC score	0.037808 (rank : 103)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	189	Target Neighborhood Hits	949	Shared Neighborhood Hits	77
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CENPE_HUMAN
NC score	0.037590 (rank : 104)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	189	Target Neighborhood Hits	2060	Shared Neighborhood Hits	100
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RB6I2_MOUSE
NC score	0.037310 (rank : 105)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	189	Target Neighborhood Hits	1433	Shared Neighborhood Hits	88
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

CCDC3_MOUSE
NC score	0.036976 (rank : 106)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	189	Target Neighborhood Hits	131	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

GAS8_HUMAN
NC score	0.036732 (rank : 107)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	189	Target Neighborhood Hits	819	Shared Neighborhood Hits	78
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

MY18A_HUMAN
NC score	0.036537 (rank : 108)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	189	Target Neighborhood Hits	1929	Shared Neighborhood Hits	122
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RB6I2_HUMAN
NC score	0.036523 (rank : 109)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	189	Target Neighborhood Hits	1584	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

CENPF_HUMAN
NC score	0.036097 (rank : 110)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	189	Target Neighborhood Hits	1932	Shared Neighborhood Hits	92
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

BICD2_MOUSE
NC score	0.034689 (rank : 111)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	189	Target Neighborhood Hits	864	Shared Neighborhood Hits	79
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BPA1_MOUSE
NC score	0.034568 (rank : 112)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	189	Target Neighborhood Hits	1477	Shared Neighborhood Hits	89
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCDC3_HUMAN
NC score	0.034483 (rank : 113)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	189	Target Neighborhood Hits	111	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQI4	Gene names	CCDC3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

CCD91_MOUSE
NC score	0.033713 (rank : 114)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	189	Target Neighborhood Hits	699	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

BICD2_HUMAN
NC score	0.033334 (rank : 115)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	189	Target Neighborhood Hits	856	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

RAI14_MOUSE
NC score	0.032728 (rank : 116)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	189	Target Neighborhood Hits	1505	Shared Neighborhood Hits	93
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

PTN13_HUMAN
NC score	0.032570 (rank : 117)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	189	Target Neighborhood Hits	471	Shared Neighborhood Hits	55
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

MAP1B_HUMAN
NC score	0.031757 (rank : 118)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	189	Target Neighborhood Hits	903	Shared Neighborhood Hits	59
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

RIMB1_MOUSE
NC score	0.031642 (rank : 119)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	189	Target Neighborhood Hits	1376	Shared Neighborhood Hits	90
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

MAP1B_MOUSE
NC score	0.031343 (rank : 120)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	189	Target Neighborhood Hits	977	Shared Neighborhood Hits	67
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NCOR2_MOUSE
NC score	0.030125 (rank : 121)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	189	Target Neighborhood Hits	790	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

VAPB_MOUSE
NC score	0.029945 (rank : 122)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	189	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY76	Gene names	Vapb
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B (VAMP- associated protein B) (VAMP-associated protein 33b) (VAMP-B) (VAP-B).

RILP_MOUSE
NC score	0.029492 (rank : 123)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	189	Target Neighborhood Hits	257	Shared Neighborhood Hits	42
SwissProt Accessions	Q5ND29, Q80WB8, Q8CHY9	Gene names	Rilp
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

OXR1_HUMAN
NC score	0.029271 (rank : 124)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	189	Target Neighborhood Hits	282	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N573, Q3LIB5, Q6ZVK9, Q8N8V0, Q9H266, Q9NWC7	Gene names	OXR1
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1.

DOCK4_MOUSE
NC score	0.028670 (rank : 125)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	189	Target Neighborhood Hits	210	Shared Neighborhood Hits	12
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

MYH7_HUMAN
NC score	0.028331 (rank : 126)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	189	Target Neighborhood Hits	1559	Shared Neighborhood Hits	86
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

STMN1_HUMAN
NC score	0.027056 (rank : 127)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	189	Target Neighborhood Hits	554	Shared Neighborhood Hits	60
SwissProt Accessions	P16949	Gene names	STMN1, LAP18, OP18
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Protein Pr22).

NFM_HUMAN
NC score	0.026884 (rank : 128)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	189	Target Neighborhood Hits	1328	Shared Neighborhood Hits	90
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

MYO5C_HUMAN
NC score	0.026627 (rank : 129)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	189	Target Neighborhood Hits	1206	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NFM_MOUSE
NC score	0.026569 (rank : 130)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	189	Target Neighborhood Hits	1159	Shared Neighborhood Hits	83
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

PPRB_HUMAN
NC score	0.026367 (rank : 131)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	189	Target Neighborhood Hits	311	Shared Neighborhood Hits	15
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

TAB3_HUMAN
NC score	0.025972 (rank : 132)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	189	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

STMN1_MOUSE
NC score	0.025843 (rank : 133)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	189	Target Neighborhood Hits	560	Shared Neighborhood Hits	61
SwissProt Accessions	P54227	Gene names	Stmn1, Lag, Lap18, Pr22
Domain Architecture
Description	Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) (Leukemia-associated gene protein).

APC_MOUSE
NC score	0.025740 (rank : 134)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	189	Target Neighborhood Hits	441	Shared Neighborhood Hits	46
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

DOCK4_HUMAN
NC score	0.025571 (rank : 135)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	189	Target Neighborhood Hits	237	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

VIME_HUMAN
NC score	0.024209 (rank : 136)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	189	Target Neighborhood Hits	706	Shared Neighborhood Hits	72
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

PACS1_HUMAN
NC score	0.024025 (rank : 137)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	189	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

BSN_MOUSE
NC score	0.023985 (rank : 138)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	189	Target Neighborhood Hits	2057	Shared Neighborhood Hits	91
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

VIME_MOUSE
NC score	0.023845 (rank : 139)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	189	Target Neighborhood Hits	716	Shared Neighborhood Hits	74
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

PACS1_MOUSE
NC score	0.023795 (rank : 140)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PKHG1_HUMAN
NC score	0.023266 (rank : 141)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	189	Target Neighborhood Hits	174	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

TLN1_MOUSE
NC score	0.023215 (rank : 142)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	189	Target Neighborhood Hits	213	Shared Neighborhood Hits	18
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TAB3_MOUSE
NC score	0.023055 (rank : 143)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	189	Target Neighborhood Hits	273	Shared Neighborhood Hits	13
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

NSDHL_MOUSE
NC score	0.022903 (rank : 144)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	189	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1J0, O55109	Gene names	Nsdhl
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170).

APC_HUMAN
NC score	0.022848 (rank : 145)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	189	Target Neighborhood Hits	603	Shared Neighborhood Hits	48
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

SPTB1_MOUSE
NC score	0.021621 (rank : 146)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	189	Target Neighborhood Hits	543	Shared Neighborhood Hits	65
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

KCNB2_HUMAN
NC score	0.020748 (rank : 147)	θ value	0.0330416 (rank : 20)
Query Neighborhood Hits	189	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KIF3A_MOUSE
NC score	0.020640 (rank : 148)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	189	Target Neighborhood Hits	715	Shared Neighborhood Hits	75
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

TLN2_MOUSE
NC score	0.020410 (rank : 149)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	189	Target Neighborhood Hits	149	Shared Neighborhood Hits	9
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
NC score	0.020203 (rank : 150)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	189	Target Neighborhood Hits	157	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

NCOR2_HUMAN
NC score	0.019655 (rank : 151)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	189	Target Neighborhood Hits	870	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NU214_HUMAN
NC score	0.018200 (rank : 152)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	189	Target Neighborhood Hits	657	Shared Neighborhood Hits	38
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

DOCK3_HUMAN
NC score	0.016660 (rank : 153)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	189	Target Neighborhood Hits	87	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

ROCK2_MOUSE
NC score	0.016201 (rank : 154)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	189	Target Neighborhood Hits	2072	Shared Neighborhood Hits	97
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

SH22A_MOUSE
NC score	0.015571 (rank : 155)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	189	Target Neighborhood Hits	179	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

ROCK2_HUMAN
NC score	0.015280 (rank : 156)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	189	Target Neighborhood Hits	2073	Shared Neighborhood Hits	96
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

CT112_HUMAN
NC score	0.014553 (rank : 157)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	189	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q96MY1, Q5JYB7, Q6P0Y4, Q9BR34, Q9NQF6	Gene names	C20orf112
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112.

SET1A_HUMAN
NC score	0.014077 (rank : 158)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	189	Target Neighborhood Hits	690	Shared Neighborhood Hits	26
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

HTF4_MOUSE
NC score	0.013001 (rank : 159)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	189	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

SMCA2_HUMAN
NC score	0.012658 (rank : 160)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	189	Target Neighborhood Hits	503	Shared Neighborhood Hits	37
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

RHPN2_HUMAN
NC score	0.012512 (rank : 161)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	189	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUC4, Q8N3T7, Q8N9D6, Q8NE33, Q96RU1	Gene names	RHPN2
Domain Architecture	No domain graphic available
Description	Rhophilin-2 (GTP-Rho-binding protein 2) (76 kDa RhoB effector protein) (p76RBE).

DCR1A_MOUSE
NC score	0.012207 (rank : 162)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	189	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

OTOF_HUMAN
NC score	0.011770 (rank : 163)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	189	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

SCYBG_MOUSE
NC score	0.011104 (rank : 164)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	189	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BSU2, Q8VE25, Q9EPB3	Gene names	Cxcl16, Srpsox
Domain Architecture	No domain graphic available
Description	Small inducible cytokine B16 precursor (Transmembrane chemokine CXCL16) (SR-PSOX) (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein).

NPBL_MOUSE
NC score	0.011003 (rank : 165)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	189	Target Neighborhood Hits	1041	Shared Neighborhood Hits	40
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

RPTN_HUMAN
NC score	0.010781 (rank : 166)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	189	Target Neighborhood Hits	406	Shared Neighborhood Hits	13
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

NFAT5_MOUSE
NC score	0.010745 (rank : 167)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	189	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

TEX2_MOUSE
NC score	0.010620 (rank : 168)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	189	Target Neighborhood Hits	121	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZPJ0	Gene names	Tex2, Kiaa1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TULP2_HUMAN
NC score	0.010585 (rank : 169)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	189	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O00295	Gene names	TULP2
Domain Architecture
Description	Tubby-related protein 2 (Tubby-like protein 2).

FA53C_MOUSE
NC score	0.010114 (rank : 170)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	189	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BXQ8, Q3U4J2	Gene names	Fam53c
Domain Architecture	No domain graphic available
Description	Protein FAM53C.

LOXL1_MOUSE
NC score	0.009877 (rank : 171)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	189	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

POPD1_HUMAN
NC score	0.008534 (rank : 172)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	189	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NE79, Q8IWC6, Q9HBV0, Q9UNG6	Gene names	BVES, POP1, POPDC1
Domain Architecture
Description	Blood vessel epicardial substance (hBVES) (Popeye domain-containing protein 1) (Popeye protein 1).

MYO15_MOUSE
NC score	0.008184 (rank : 173)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	189	Target Neighborhood Hits	467	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYCD_MOUSE
NC score	0.007857 (rank : 174)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	189	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

PXDC1_MOUSE
NC score	0.007716 (rank : 175)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	189	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZV7, Q8BM20, Q9CWV5	Gene names	Plxdc1, Tem7
Domain Architecture	No domain graphic available
Description	Plexin domain-containing protein 1 precursor (Tumor endothelial marker 7).

GP149_MOUSE
NC score	0.007534 (rank : 176)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	189	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q3UVY1, Q3TMB1, Q80T52, Q8BXA3, Q8BZC0	Gene names	Gpr149, Pgr10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

SPY2_HUMAN
NC score	0.005144 (rank : 177)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	189	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

VMDL3_HUMAN
NC score	0.004703 (rank : 178)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	189	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N1M1, Q8N356, Q8NFT9, Q9BR80	Gene names	VMD2L3
Domain Architecture
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

KS6C1_HUMAN
NC score	0.004533 (rank : 179)	θ value	2.36792 (rank : 91)
Query Neighborhood Hits	189	Target Neighborhood Hits	682	Shared Neighborhood Hits	7
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

SEM6A_MOUSE
NC score	0.004255 (rank : 180)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	189	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	O35464, Q6P5A8, Q6PCN9, Q9EQ71	Gene names	Sema6a, Semaq
Domain Architecture
Description	Semaphorin-6A precursor (Semaphorin VIA) (Sema VIA) (Semaphorin 6A-1) (SEMA6A-1) (Semaphorin Q) (Sema Q).

KCNH4_HUMAN
NC score	0.003357 (rank : 181)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	189	Target Neighborhood Hits	177	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

GNAS1_MOUSE
NC score	0.003297 (rank : 182)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	189	Target Neighborhood Hits	651	Shared Neighborhood Hits	15
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

CSPG2_HUMAN
NC score	0.002629 (rank : 183)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	189	Target Neighborhood Hits	681	Shared Neighborhood Hits	10
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

BMPR2_MOUSE
NC score	0.002462 (rank : 184)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	189	Target Neighborhood Hits	738	Shared Neighborhood Hits	12
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

CSKP_HUMAN
NC score	0.002426 (rank : 185)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	189	Target Neighborhood Hits	1022	Shared Neighborhood Hits	34
SwissProt Accessions	O14936, O43215, Q9NYB3	Gene names	CASK, LIN2
Domain Architecture
Description	Peripheral plasma membrane protein CASK (EC 2.7.11.1) (hCASK) (Calcium/calmodulin-dependent serine protein kinase) (Lin-2 homolog).

WEE1B_HUMAN
NC score	0.001153 (rank : 186)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	189	Target Neighborhood Hits	836	Shared Neighborhood Hits	13
SwissProt Accessions	P0C1S8	Gene names	WEE1B, WEE2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase).

LDLR_MOUSE
NC score	0.000751 (rank : 187)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	189	Target Neighborhood Hits	382	Shared Neighborhood Hits	3
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

BMPR2_HUMAN
NC score	0.000400 (rank : 188)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	189	Target Neighborhood Hits	736	Shared Neighborhood Hits	9
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

OBSCN_HUMAN
NC score	-0.000778 (rank : 189)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	189	Target Neighborhood Hits	1931	Shared Neighborhood Hits	25
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

INSRR_MOUSE
NC score	-0.002429 (rank : 190)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	189	Target Neighborhood Hits	961	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].