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Network neighborhood for query Sequence : PACS1_HUMAN

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PACS1_HUMAN
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PACS1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PACS1_MOUSE
θ value	0 (rank : 2)	NC score	0.988326 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	87	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

CASP_HUMAN
θ value	0.00228821 (rank : 3)	NC score	0.083595 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	1131	Shared Neighborhood Hits	30
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	0.00228821 (rank : 4)	NC score	0.084466 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	1152	Shared Neighborhood Hits	30
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

DSPP_HUMAN
θ value	0.00228821 (rank : 5)	NC score	0.111166 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	645	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NFH_HUMAN
θ value	0.00298849 (rank : 6)	NC score	0.073835 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	1242	Shared Neighborhood Hits	46
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

AFF4_HUMAN
θ value	0.00665767 (rank : 7)	NC score	0.119316 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	611	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

NFH_MOUSE
θ value	0.0193708 (rank : 8)	NC score	0.058660 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	2247	Shared Neighborhood Hits	49
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CUTL1_HUMAN
θ value	0.0563607 (rank : 9)	NC score	0.079011 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	1574	Shared Neighborhood Hits	39
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
θ value	0.0563607 (rank : 10)	NC score	0.079952 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	1620	Shared Neighborhood Hits	40
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

AFF4_MOUSE
θ value	0.0736092 (rank : 11)	NC score	0.107121 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	581	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

GP158_HUMAN
θ value	0.0961366 (rank : 12)	NC score	0.083140 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	221	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

TCOF_MOUSE
θ value	0.0961366 (rank : 13)	NC score	0.099761 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	471	Shared Neighborhood Hits	31
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TP53B_MOUSE
θ value	0.0961366 (rank : 14)	NC score	0.090477 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	644	Shared Neighborhood Hits	24
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

RGS3_HUMAN
θ value	0.125558 (rank : 15)	NC score	0.039063 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	1375	Shared Neighborhood Hits	32
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TBX21_MOUSE
θ value	0.279714 (rank : 16)	NC score	0.036095 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

JHD1B_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.042861 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	214	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

MAML1_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.047552 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PCLO_MOUSE
θ value	0.47712 (rank : 19)	NC score	0.059155 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	2275	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PTN13_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.022819 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	471	Shared Neighborhood Hits	12
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

BSN_MOUSE
θ value	0.62314 (rank : 21)	NC score	0.065574 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	2057	Shared Neighborhood Hits	48
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MDC1_MOUSE
θ value	0.62314 (rank : 22)	NC score	0.063709 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	998	Shared Neighborhood Hits	38
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NACAM_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.064866 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	1866	Shared Neighborhood Hits	52
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NEST_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.047784 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	1305	Shared Neighborhood Hits	34
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

NFM_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.039939 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	1328	Shared Neighborhood Hits	43
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

RBBP6_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.069344 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	1135	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

WNK1_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.019791 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	1158	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

AP3B2_HUMAN
θ value	0.813845 (rank : 28)	NC score	0.041607 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	246	Shared Neighborhood Hits	10
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

TITIN_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.018212 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	2923	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

WNK1_MOUSE
θ value	0.813845 (rank : 30)	NC score	0.014884 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	1179	Shared Neighborhood Hits	20
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

PRRT3_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.043627 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	998	Shared Neighborhood Hits	27
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TRPS1_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.035583 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	609	Shared Neighborhood Hits	10
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

PALM_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.062184 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

BSN_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.061460 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	1537	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CIC_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.042937 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	742	Shared Neighborhood Hits	26
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CRTC1_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.058745 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	230	Shared Neighborhood Hits	17
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

ABTAP_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.037151 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	381	Shared Neighborhood Hits	16
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

APC_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.049710 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	441	Shared Neighborhood Hits	28
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

DSPP_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.071564 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

JIP3_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.035595 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	1039	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

PAK6_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.005075 (rank : 86)
Query Neighborhood Hits	82	Target Neighborhood Hits	915	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

SAPS1_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.028340 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	704	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SI1L1_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.024025 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	189	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

ACD_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.050699 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	143	Shared Neighborhood Hits	11
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

CSPG2_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.012947 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	711	Shared Neighborhood Hits	18
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

IPR1_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.042964 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

K1219_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.038808 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

LTBP2_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.006802 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	617	Shared Neighborhood Hits	8
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MAML2_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.037307 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	360	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

MYPT1_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.016575 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	723	Shared Neighborhood Hits	15
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

SOX5_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.024954 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

SYNE2_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.020501 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	1323	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TARA_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.063892 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	1626	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRAK1_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.029232 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	660	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

CAC1G_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.018956 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	587	Shared Neighborhood Hits	18
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

HIP1R_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.030205 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	959	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

LEUK_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.039444 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	147	Shared Neighborhood Hits	12
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

RPGR_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.019316 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	281	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

STON2_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.021367 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

TACC3_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.035940 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	779	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

DDX23_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.011255 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	486	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

GOGA3_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.023387 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	1437	Shared Neighborhood Hits	32
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

MAGAB_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.014050 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P43364, Q5ETU4, Q6ZRZ5	Gene names	MAGEA11, MAGE11
Domain Architecture
Description	Melanoma-associated antigen 11 (MAGE-11 antigen).

MAP1A_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.047309 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	1626	Shared Neighborhood Hits	45
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SETD2_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.033030 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	412	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SLAF6_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.029929 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DU3, Q5TAT3, Q96DV0	Gene names	SLAMF6, KALI
Domain Architecture	No domain graphic available
Description	SLAM family member 6 precursor (NK-T-B-antigen) (NTB-A) (Activating NK receptor).

SOX5_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.022857 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

BPTF_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.034793 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	786	Shared Neighborhood Hits	32
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

EDD1_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.012470 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

LIPA3_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.022152 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	828	Shared Neighborhood Hits	22
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

MAGB6_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.024792 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	184	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N7X4, Q6GS19, Q9H219	Gene names	MAGEB6
Domain Architecture
Description	Melanoma-associated antigen B6 (MAGE-B6 antigen).

SDPR_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.032528 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	337	Shared Neighborhood Hits	20
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SRRM2_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.048329 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	1470	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TMC2_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.017062 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	149	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

AHI1_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.008133 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	537	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

IF4B_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.027257 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	417	Shared Neighborhood Hits	16
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MYPT1_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.012879 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	539	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

PCOC1_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.011322 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

RL1D1_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.058209 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

TAF6L_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.020812 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

TXLNB_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.026334 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	912	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

UN119_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.017334 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2R6	Gene names	Unc119, Unc119h
Domain Architecture
Description	Unc-119 protein homolog (Retinal protein 4) (MRG4).

AFF1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.055180 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	506	Shared Neighborhood Hits	28
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CUTL2_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.059735 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

CUTL2_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.062997 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	771	Shared Neighborhood Hits	25
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

TGON2_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.053324 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	1037	Shared Neighborhood Hits	42
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

Hits sorted by NC score

PACS1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PACS1_MOUSE
NC score	0.988326 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	87	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

AFF4_HUMAN
NC score	0.119316 (rank : 3)	θ value	0.00665767 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	611	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

DSPP_HUMAN
NC score	0.111166 (rank : 4)	θ value	0.00228821 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	645	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

AFF4_MOUSE
NC score	0.107121 (rank : 5)	θ value	0.0736092 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	581	Shared Neighborhood Hits	29
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

TCOF_MOUSE
NC score	0.099761 (rank : 6)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	471	Shared Neighborhood Hits	31
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TP53B_MOUSE
NC score	0.090477 (rank : 7)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	644	Shared Neighborhood Hits	24
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

CASP_MOUSE
NC score	0.084466 (rank : 8)	θ value	0.00228821 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	1152	Shared Neighborhood Hits	30
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_HUMAN
NC score	0.083595 (rank : 9)	θ value	0.00228821 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	1131	Shared Neighborhood Hits	30
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

GP158_HUMAN
NC score	0.083140 (rank : 10)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	221	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

CUTL1_MOUSE
NC score	0.079952 (rank : 11)	θ value	0.0563607 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	1620	Shared Neighborhood Hits	40
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CUTL1_HUMAN
NC score	0.079011 (rank : 12)	θ value	0.0563607 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	1574	Shared Neighborhood Hits	39
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

NFH_HUMAN
NC score	0.073835 (rank : 13)	θ value	0.00298849 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	1242	Shared Neighborhood Hits	46
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DSPP_MOUSE
NC score	0.071564 (rank : 14)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RBBP6_HUMAN
NC score	0.069344 (rank : 15)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	1135	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

BSN_MOUSE
NC score	0.065574 (rank : 16)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	2057	Shared Neighborhood Hits	48
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NACAM_MOUSE
NC score	0.064866 (rank : 17)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	1866	Shared Neighborhood Hits	52
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TARA_HUMAN
NC score	0.063892 (rank : 18)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	1626	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

MDC1_MOUSE
NC score	0.063709 (rank : 19)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	998	Shared Neighborhood Hits	38
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

CUTL2_MOUSE
NC score	0.062997 (rank : 20)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	771	Shared Neighborhood Hits	25
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

PALM_MOUSE
NC score	0.062184 (rank : 21)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

BSN_HUMAN
NC score	0.061460 (rank : 22)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	1537	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CUTL2_HUMAN
NC score	0.059735 (rank : 23)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

PCLO_MOUSE
NC score	0.059155 (rank : 24)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	2275	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CRTC1_MOUSE
NC score	0.058745 (rank : 25)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	230	Shared Neighborhood Hits	17
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

NFH_MOUSE
NC score	0.058660 (rank : 26)	θ value	0.0193708 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	2247	Shared Neighborhood Hits	49
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RL1D1_HUMAN
NC score	0.058209 (rank : 27)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

AFF1_HUMAN
NC score	0.055180 (rank : 28)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	506	Shared Neighborhood Hits	28
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

TGON2_HUMAN
NC score	0.053324 (rank : 29)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	82	Target Neighborhood Hits	1037	Shared Neighborhood Hits	42
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ACD_HUMAN
NC score	0.050699 (rank : 30)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	143	Shared Neighborhood Hits	11
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

APC_MOUSE
NC score	0.049710 (rank : 31)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	441	Shared Neighborhood Hits	28
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

SRRM2_MOUSE
NC score	0.048329 (rank : 32)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	1470	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NEST_HUMAN
NC score	0.047784 (rank : 33)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	1305	Shared Neighborhood Hits	34
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

MAML1_MOUSE
NC score	0.047552 (rank : 34)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MAP1A_HUMAN
NC score	0.047309 (rank : 35)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	1626	Shared Neighborhood Hits	45
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PRRT3_HUMAN
NC score	0.043627 (rank : 36)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	998	Shared Neighborhood Hits	27
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

IPR1_MOUSE
NC score	0.042964 (rank : 37)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

CIC_MOUSE
NC score	0.042937 (rank : 38)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	742	Shared Neighborhood Hits	26
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

JHD1B_MOUSE
NC score	0.042861 (rank : 39)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	214	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

AP3B2_HUMAN
NC score	0.041607 (rank : 40)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	246	Shared Neighborhood Hits	10
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

NFM_HUMAN
NC score	0.039939 (rank : 41)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	1328	Shared Neighborhood Hits	43
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

LEUK_MOUSE
NC score	0.039444 (rank : 42)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	147	Shared Neighborhood Hits	12
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

RGS3_HUMAN
NC score	0.039063 (rank : 43)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	1375	Shared Neighborhood Hits	32
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

K1219_HUMAN
NC score	0.038808 (rank : 44)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

MAML2_HUMAN
NC score	0.037307 (rank : 45)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	360	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

ABTAP_MOUSE
NC score	0.037151 (rank : 46)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	381	Shared Neighborhood Hits	16
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

TBX21_MOUSE
NC score	0.036095 (rank : 47)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TACC3_HUMAN
NC score	0.035940 (rank : 48)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	779	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

JIP3_HUMAN
NC score	0.035595 (rank : 49)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	1039	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

TRPS1_MOUSE
NC score	0.035583 (rank : 50)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	609	Shared Neighborhood Hits	10
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

BPTF_HUMAN
NC score	0.034793 (rank : 51)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	786	Shared Neighborhood Hits	32
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SETD2_HUMAN
NC score	0.033030 (rank : 52)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	412	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SDPR_HUMAN
NC score	0.032528 (rank : 53)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	337	Shared Neighborhood Hits	20
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

HIP1R_MOUSE
NC score	0.030205 (rank : 54)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	959	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

SLAF6_HUMAN
NC score	0.029929 (rank : 55)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DU3, Q5TAT3, Q96DV0	Gene names	SLAMF6, KALI
Domain Architecture	No domain graphic available
Description	SLAM family member 6 precursor (NK-T-B-antigen) (NTB-A) (Activating NK receptor).

TRAK1_HUMAN
NC score	0.029232 (rank : 56)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	660	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

SAPS1_HUMAN
NC score	0.028340 (rank : 57)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	704	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

IF4B_HUMAN
NC score	0.027257 (rank : 58)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	417	Shared Neighborhood Hits	16
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

TXLNB_HUMAN
NC score	0.026334 (rank : 59)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	912	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

SOX5_HUMAN
NC score	0.024954 (rank : 60)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	219	Shared Neighborhood Hits	13
SwissProt Accessions	P35711, Q86UK8, Q8J017, Q8J018, Q8J019, Q8J020, Q8N1D9, Q8N7E0, Q8TEA4	Gene names	SOX5
Domain Architecture
Description	Transcription factor SOX-5.

MAGB6_HUMAN
NC score	0.024792 (rank : 61)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	184	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N7X4, Q6GS19, Q9H219	Gene names	MAGEB6
Domain Architecture
Description	Melanoma-associated antigen B6 (MAGE-B6 antigen).

SI1L1_MOUSE
NC score	0.024025 (rank : 62)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	189	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

GOGA3_MOUSE
NC score	0.023387 (rank : 63)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	1437	Shared Neighborhood Hits	32
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

SOX5_MOUSE
NC score	0.022857 (rank : 64)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	P35710, O88184, O89018	Gene names	Sox5, Sox-5
Domain Architecture
Description	Transcription factor SOX-5.

PTN13_HUMAN
NC score	0.022819 (rank : 65)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	471	Shared Neighborhood Hits	12
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

LIPA3_HUMAN
NC score	0.022152 (rank : 66)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	828	Shared Neighborhood Hits	22
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

STON2_HUMAN
NC score	0.021367 (rank : 67)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

TAF6L_MOUSE
NC score	0.020812 (rank : 68)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

SYNE2_HUMAN
NC score	0.020501 (rank : 69)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	1323	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

WNK1_HUMAN
NC score	0.019791 (rank : 70)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	1158	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

RPGR_MOUSE
NC score	0.019316 (rank : 71)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	281	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

CAC1G_HUMAN
NC score	0.018956 (rank : 72)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	587	Shared Neighborhood Hits	18
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

TITIN_HUMAN
NC score	0.018212 (rank : 73)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	2923	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

UN119_MOUSE
NC score	0.017334 (rank : 74)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2R6	Gene names	Unc119, Unc119h
Domain Architecture
Description	Unc-119 protein homolog (Retinal protein 4) (MRG4).

TMC2_HUMAN
NC score	0.017062 (rank : 75)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	149	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

MYPT1_HUMAN
NC score	0.016575 (rank : 76)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	723	Shared Neighborhood Hits	15
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

WNK1_MOUSE
NC score	0.014884 (rank : 77)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	1179	Shared Neighborhood Hits	20
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

MAGAB_HUMAN
NC score	0.014050 (rank : 78)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P43364, Q5ETU4, Q6ZRZ5	Gene names	MAGEA11, MAGE11
Domain Architecture
Description	Melanoma-associated antigen 11 (MAGE-11 antigen).

CSPG2_MOUSE
NC score	0.012947 (rank : 79)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	711	Shared Neighborhood Hits	18
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

MYPT1_MOUSE
NC score	0.012879 (rank : 80)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	539	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

EDD1_MOUSE
NC score	0.012470 (rank : 81)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TP3, Q698K9, Q6PEQ8, Q6PFQ9, Q80VL4, Q810V6, Q9CXE9	Gene names	Edd1, Edd, Kiaa0896
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase EDD1 (EC 6.3.2.-) (Hyperplastic discs protein homolog).

PCOC1_HUMAN
NC score	0.011322 (rank : 82)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

DDX23_HUMAN
NC score	0.011255 (rank : 83)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	486	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

AHI1_HUMAN
NC score	0.008133 (rank : 84)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	537	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

LTBP2_MOUSE
NC score	0.006802 (rank : 85)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	617	Shared Neighborhood Hits	8
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

PAK6_HUMAN
NC score	0.005075 (rank : 86)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	915	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).