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Network neighborhood for query Sequence : SI1L1_HUMAN

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SI1L1_HUMAN
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SI1L1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	162	Target Neighborhood Hits	162	Shared Neighborhood Hits	162
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
θ value	0 (rank : 2)	NC score	0.994143 (rank : 2)
Query Neighborhood Hits	162	Target Neighborhood Hits	189	Shared Neighborhood Hits	113
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SI1L2_HUMAN
θ value	0 (rank : 3)	NC score	0.977285 (rank : 4)
Query Neighborhood Hits	162	Target Neighborhood Hits	131	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_MOUSE
θ value	0 (rank : 4)	NC score	0.978058 (rank : 3)
Query Neighborhood Hits	162	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L3_HUMAN
θ value	0 (rank : 5)	NC score	0.954631 (rank : 5)
Query Neighborhood Hits	162	Target Neighborhood Hits	305	Shared Neighborhood Hits	45
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SIPA1_HUMAN
θ value	6.75929e-181 (rank : 6)	NC score	0.929786 (rank : 7)
Query Neighborhood Hits	162	Target Neighborhood Hits	250	Shared Neighborhood Hits	44
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SIPA1_MOUSE
θ value	9.45368e-175 (rank : 7)	NC score	0.940008 (rank : 6)
Query Neighborhood Hits	162	Target Neighborhood Hits	158	Shared Neighborhood Hits	32
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

RGP2_HUMAN
θ value	9.45883e-58 (rank : 8)	NC score	0.883970 (rank : 8)
Query Neighborhood Hits	162	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

GRIPE_HUMAN
θ value	7.09661e-13 (rank : 9)	NC score	0.458304 (rank : 9)
Query Neighborhood Hits	162	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
θ value	6.00763e-12 (rank : 10)	NC score	0.445664 (rank : 10)
Query Neighborhood Hits	162	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TSC2_HUMAN
θ value	2.52405e-10 (rank : 11)	NC score	0.432395 (rank : 11)
Query Neighborhood Hits	162	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TSC2_MOUSE
θ value	1.06045e-08 (rank : 12)	NC score	0.410810 (rank : 12)
Query Neighborhood Hits	162	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

SHAN1_HUMAN
θ value	0.00035302 (rank : 13)	NC score	0.101111 (rank : 24)
Query Neighborhood Hits	162	Target Neighborhood Hits	1041	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

HOME2_MOUSE
θ value	0.00869519 (rank : 14)	NC score	0.055499 (rank : 41)
Query Neighborhood Hits	162	Target Neighborhood Hits	882	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

SHAN2_HUMAN
θ value	0.0113563 (rank : 15)	NC score	0.145236 (rank : 13)
Query Neighborhood Hits	162	Target Neighborhood Hits	346	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SHAN2_MOUSE
θ value	0.0148317 (rank : 16)	NC score	0.131771 (rank : 17)
Query Neighborhood Hits	162	Target Neighborhood Hits	446	Shared Neighborhood Hits	41
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

PARD3_MOUSE
θ value	0.0252991 (rank : 17)	NC score	0.089154 (rank : 27)
Query Neighborhood Hits	162	Target Neighborhood Hits	290	Shared Neighborhood Hits	45
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

APBA2_HUMAN
θ value	0.0330416 (rank : 18)	NC score	0.136433 (rank : 15)
Query Neighborhood Hits	162	Target Neighborhood Hits	220	Shared Neighborhood Hits	39
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_MOUSE
θ value	0.0330416 (rank : 19)	NC score	0.136462 (rank : 14)
Query Neighborhood Hits	162	Target Neighborhood Hits	219	Shared Neighborhood Hits	39
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

EEA1_MOUSE
θ value	0.0431538 (rank : 20)	NC score	0.041946 (rank : 59)
Query Neighborhood Hits	162	Target Neighborhood Hits	1637	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

PARD3_HUMAN
θ value	0.0431538 (rank : 21)	NC score	0.082732 (rank : 29)
Query Neighborhood Hits	162	Target Neighborhood Hits	312	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

LZTS1_MOUSE
θ value	0.0563607 (rank : 22)	NC score	0.047936 (rank : 50)
Query Neighborhood Hits	162	Target Neighborhood Hits	540	Shared Neighborhood Hits	55
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

APBA1_HUMAN
θ value	0.0736092 (rank : 23)	NC score	0.121276 (rank : 18)
Query Neighborhood Hits	162	Target Neighborhood Hits	325	Shared Neighborhood Hits	44
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

FILA_HUMAN
θ value	0.0736092 (rank : 24)	NC score	0.038430 (rank : 69)
Query Neighborhood Hits	162	Target Neighborhood Hits	685	Shared Neighborhood Hits	21
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

NHERF_HUMAN
θ value	0.0736092 (rank : 25)	NC score	0.120604 (rank : 19)
Query Neighborhood Hits	162	Target Neighborhood Hits	190	Shared Neighborhood Hits	40
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

APBA3_MOUSE
θ value	0.0961366 (rank : 26)	NC score	0.134827 (rank : 16)
Query Neighborhood Hits	162	Target Neighborhood Hits	174	Shared Neighborhood Hits	40
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

ARHGB_HUMAN
θ value	0.0961366 (rank : 27)	NC score	0.072528 (rank : 31)
Query Neighborhood Hits	162	Target Neighborhood Hits	375	Shared Neighborhood Hits	45
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

KCNB2_HUMAN
θ value	0.0961366 (rank : 28)	NC score	0.019915 (rank : 121)
Query Neighborhood Hits	162	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

NHERF_MOUSE
θ value	0.125558 (rank : 29)	NC score	0.113470 (rank : 21)
Query Neighborhood Hits	162	Target Neighborhood Hits	195	Shared Neighborhood Hits	40
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PDZD3_MOUSE
θ value	0.163984 (rank : 30)	NC score	0.100948 (rank : 25)
Query Neighborhood Hits	162	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

APBA3_HUMAN
θ value	0.21417 (rank : 31)	NC score	0.120032 (rank : 20)
Query Neighborhood Hits	162	Target Neighborhood Hits	201	Shared Neighborhood Hits	37
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

MAP9_MOUSE
θ value	0.279714 (rank : 32)	NC score	0.036294 (rank : 74)
Query Neighborhood Hits	162	Target Neighborhood Hits	529	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

PTN13_HUMAN
θ value	0.279714 (rank : 33)	NC score	0.035223 (rank : 76)
Query Neighborhood Hits	162	Target Neighborhood Hits	471	Shared Neighborhood Hits	44
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

USH1C_HUMAN
θ value	0.279714 (rank : 34)	NC score	0.101843 (rank : 22)
Query Neighborhood Hits	162	Target Neighborhood Hits	327	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
θ value	0.279714 (rank : 35)	NC score	0.101542 (rank : 23)
Query Neighborhood Hits	162	Target Neighborhood Hits	557	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

RUFY1_MOUSE
θ value	0.365318 (rank : 36)	NC score	0.053452 (rank : 44)
Query Neighborhood Hits	162	Target Neighborhood Hits	765	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

VAPB_MOUSE
θ value	0.365318 (rank : 37)	NC score	0.052145 (rank : 46)
Query Neighborhood Hits	162	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QY76	Gene names	Vapb
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B (VAMP- associated protein B) (VAMP-associated protein 33b) (VAMP-B) (VAP-B).

GCC2_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.042918 (rank : 56)
Query Neighborhood Hits	162	Target Neighborhood Hits	1558	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.042410 (rank : 58)
Query Neighborhood Hits	162	Target Neighborhood Hits	1559	Shared Neighborhood Hits	77
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RUFY2_HUMAN
θ value	0.47712 (rank : 40)	NC score	0.046346 (rank : 52)
Query Neighborhood Hits	162	Target Neighborhood Hits	1208	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

BPAEA_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.030362 (rank : 92)
Query Neighborhood Hits	162	Target Neighborhood Hits	1369	Shared Neighborhood Hits	70
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PPRB_HUMAN
θ value	0.62314 (rank : 42)	NC score	0.030276 (rank : 93)
Query Neighborhood Hits	162	Target Neighborhood Hits	311	Shared Neighborhood Hits	11
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SNIP_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.044151 (rank : 55)
Query Neighborhood Hits	162	Target Neighborhood Hits	319	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

TPR_HUMAN
θ value	0.62314 (rank : 44)	NC score	0.040445 (rank : 63)
Query Neighborhood Hits	162	Target Neighborhood Hits	1921	Shared Neighborhood Hits	88
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

VAPB_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.061214 (rank : 36)
Query Neighborhood Hits	162	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	O95292, O95293, Q9P0H0	Gene names	VAPB
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B/C (VAMP- associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C).

CCDC6_HUMAN
θ value	0.813845 (rank : 46)	NC score	0.058454 (rank : 38)
Query Neighborhood Hits	162	Target Neighborhood Hits	723	Shared Neighborhood Hits	64
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CK5P2_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.039427 (rank : 65)
Query Neighborhood Hits	162	Target Neighborhood Hits	1433	Shared Neighborhood Hits	75
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CYTSA_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.039018 (rank : 67)
Query Neighborhood Hits	162	Target Neighborhood Hits	1138	Shared Neighborhood Hits	69
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	0.813845 (rank : 49)	NC score	0.036615 (rank : 73)
Query Neighborhood Hits	162	Target Neighborhood Hits	1104	Shared Neighborhood Hits	65
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

GOGB1_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.032994 (rank : 80)
Query Neighborhood Hits	162	Target Neighborhood Hits	2297	Shared Neighborhood Hits	79
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

NHRF2_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.084870 (rank : 28)
Query Neighborhood Hits	162	Target Neighborhood Hits	194	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

RUFY2_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.056305 (rank : 40)
Query Neighborhood Hits	162	Target Neighborhood Hits	820	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

OXR1_MOUSE
θ value	1.38821 (rank : 53)	NC score	0.020094 (rank : 120)
Query Neighborhood Hits	162	Target Neighborhood Hits	516	Shared Neighborhood Hits	28
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

PDZ11_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.060236 (rank : 37)
Query Neighborhood Hits	162	Target Neighborhood Hits	160	Shared Neighborhood Hits	32
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PDZ11_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.057977 (rank : 39)
Query Neighborhood Hits	162	Target Neighborhood Hits	154	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

PEPL_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.042466 (rank : 57)
Query Neighborhood Hits	162	Target Neighborhood Hits	1105	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PKHG1_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.020221 (rank : 119)
Query Neighborhood Hits	162	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

RAI14_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.026344 (rank : 108)
Query Neighborhood Hits	162	Target Neighborhood Hits	1505	Shared Neighborhood Hits	76
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SYCP1_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.032675 (rank : 81)
Query Neighborhood Hits	162	Target Neighborhood Hits	1456	Shared Neighborhood Hits	70
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TBCD1_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.016925 (rank : 129)
Query Neighborhood Hits	162	Target Neighborhood Hits	276	Shared Neighborhood Hits	27
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

VAPA_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.041747 (rank : 60)
Query Neighborhood Hits	162	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P0L0, O75453, Q5U0E7, Q9UBZ2	Gene names	VAPA, VAP33
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein A (VAMP- associated protein A) (VAMP-A) (VAP-A) (33 kDa Vamp-associated protein) (VAP-33).

VAPA_MOUSE
θ value	1.38821 (rank : 62)	NC score	0.041486 (rank : 61)
Query Neighborhood Hits	162	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WV55, Q3TJM1, Q9QY77	Gene names	Vapa, Vap33
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein A (VAMP- associated protein A) (VAMP-A) (VAP-A) (33 kDa Vamp-associated protein) (VAP-33).

NHRF2_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.090692 (rank : 26)
Query Neighborhood Hits	162	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

NSDHL_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.023050 (rank : 114)
Query Neighborhood Hits	162	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1J0, O55109	Gene names	Nsdhl
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170).

SBDS_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.029925 (rank : 95)
Query Neighborhood Hits	162	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3A5, Q96FX0, Q9NV53	Gene names	SBDS
Domain Architecture
Description	Shwachman-Bodian-Diamond syndrome protein.

SMCA2_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.010868 (rank : 142)
Query Neighborhood Hits	162	Target Neighborhood Hits	503	Shared Neighborhood Hits	20
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

WHRN_MOUSE
θ value	1.81305 (rank : 67)	NC score	0.068903 (rank : 33)
Query Neighborhood Hits	162	Target Neighborhood Hits	412	Shared Neighborhood Hits	43
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

CENPE_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.029302 (rank : 101)
Query Neighborhood Hits	162	Target Neighborhood Hits	2060	Shared Neighborhood Hits	78
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

LAP4_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.047022 (rank : 51)
Query Neighborhood Hits	162	Target Neighborhood Hits	590	Shared Neighborhood Hits	47
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

NCOR2_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.021830 (rank : 115)
Query Neighborhood Hits	162	Target Neighborhood Hits	790	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

RAD50_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.029562 (rank : 99)
Query Neighborhood Hits	162	Target Neighborhood Hits	1366	Shared Neighborhood Hits	69
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RUFY1_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.055218 (rank : 42)
Query Neighborhood Hits	162	Target Neighborhood Hits	848	Shared Neighborhood Hits	65
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

ZCH10_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.045559 (rank : 54)
Query Neighborhood Hits	162	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

CK5P2_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.037667 (rank : 70)
Query Neighborhood Hits	162	Target Neighborhood Hits	1151	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CNOT4_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.014407 (rank : 133)
Query Neighborhood Hits	162	Target Neighborhood Hits	277	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

GOGA4_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.040248 (rank : 64)
Query Neighborhood Hits	162	Target Neighborhood Hits	2034	Shared Neighborhood Hits	86
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HOOK3_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.033706 (rank : 79)
Query Neighborhood Hits	162	Target Neighborhood Hits	1070	Shared Neighborhood Hits	72
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HOOK3_MOUSE
θ value	3.0926 (rank : 78)	NC score	0.033882 (rank : 78)
Query Neighborhood Hits	162	Target Neighborhood Hits	1007	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

MACOI_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.036252 (rank : 75)
Query Neighborhood Hits	162	Target Neighborhood Hits	620	Shared Neighborhood Hits	56
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MPDZ_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.052545 (rank : 45)
Query Neighborhood Hits	162	Target Neighborhood Hits	261	Shared Neighborhood Hits	39
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

MPDZ_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.050523 (rank : 49)
Query Neighborhood Hits	162	Target Neighborhood Hits	298	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

SBDS_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.027233 (rank : 106)
Query Neighborhood Hits	162	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P70122, Q3TG78, Q9CR18	Gene names	Sbds
Domain Architecture
Description	Shwachman-Bodian-Diamond syndrome protein homolog (Protein 22A3).

THAP6_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.046031 (rank : 53)
Query Neighborhood Hits	162	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TBB0	Gene names	THAP6
Domain Architecture
Description	THAP domain-containing protein 6.

TNIP3_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.039357 (rank : 66)
Query Neighborhood Hits	162	Target Neighborhood Hits	511	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

ANR26_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.024271 (rank : 111)
Query Neighborhood Hits	162	Target Neighborhood Hits	1614	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BPAEA_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.034019 (rank : 77)
Query Neighborhood Hits	162	Target Neighborhood Hits	1480	Shared Neighborhood Hits	74
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

EEA1_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.037353 (rank : 71)
Query Neighborhood Hits	162	Target Neighborhood Hits	1796	Shared Neighborhood Hits	77
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

HMMR_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.036827 (rank : 72)
Query Neighborhood Hits	162	Target Neighborhood Hits	1082	Shared Neighborhood Hits	71
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

IASPP_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.009828 (rank : 143)
Query Neighborhood Hits	162	Target Neighborhood Hits	688	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LAP4_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.040987 (rank : 62)
Query Neighborhood Hits	162	Target Neighborhood Hits	608	Shared Neighborhood Hits	44
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

LIPA1_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.028531 (rank : 103)
Query Neighborhood Hits	162	Target Neighborhood Hits	1294	Shared Neighborhood Hits	77
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MD1L1_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.029584 (rank : 98)
Query Neighborhood Hits	162	Target Neighborhood Hits	1001	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MYH7_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.021060 (rank : 118)
Query Neighborhood Hits	162	Target Neighborhood Hits	1559	Shared Neighborhood Hits	74
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

NOTC2_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.001191 (rank : 161)
Query Neighborhood Hits	162	Target Neighborhood Hits	1113	Shared Neighborhood Hits	8
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

OTOF_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.012035 (rank : 135)
Query Neighborhood Hits	162	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

PDZD1_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.078498 (rank : 30)
Query Neighborhood Hits	162	Target Neighborhood Hits	190	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ST5_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.007305 (rank : 149)
Query Neighborhood Hits	162	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

WHRN_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.070884 (rank : 32)
Query Neighborhood Hits	162	Target Neighborhood Hits	325	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

CI039_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.029686 (rank : 97)
Query Neighborhood Hits	162	Target Neighborhood Hits	1171	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

COT1_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.004868 (rank : 152)
Query Neighborhood Hits	162	Target Neighborhood Hits	160	Shared Neighborhood Hits	8
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

CTGE6_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.024853 (rank : 109)
Query Neighborhood Hits	162	Target Neighborhood Hits	650	Shared Neighborhood Hits	55
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

DOCK4_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.015550 (rank : 131)
Query Neighborhood Hits	162	Target Neighborhood Hits	237	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.018770 (rank : 124)
Query Neighborhood Hits	162	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DYNA_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.030696 (rank : 88)
Query Neighborhood Hits	162	Target Neighborhood Hits	1194	Shared Neighborhood Hits	68
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.031368 (rank : 86)
Query Neighborhood Hits	162	Target Neighborhood Hits	1084	Shared Neighborhood Hits	66
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

GATA5_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.006937 (rank : 151)
Query Neighborhood Hits	162	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P97489	Gene names	Gata5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

HAP1_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.026681 (rank : 107)
Query Neighborhood Hits	162	Target Neighborhood Hits	606	Shared Neighborhood Hits	56
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

MAGI1_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.054811 (rank : 43)
Query Neighborhood Hits	162	Target Neighborhood Hits	388	Shared Neighborhood Hits	41
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

MAGI1_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.052127 (rank : 47)
Query Neighborhood Hits	162	Target Neighborhood Hits	403	Shared Neighborhood Hits	42
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MAP1B_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.021827 (rank : 116)
Query Neighborhood Hits	162	Target Neighborhood Hits	903	Shared Neighborhood Hits	47
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MYOC_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.051604 (rank : 48)
Query Neighborhood Hits	162	Target Neighborhood Hits	489	Shared Neighborhood Hits	53
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

RAD50_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.028989 (rank : 102)
Query Neighborhood Hits	162	Target Neighborhood Hits	1317	Shared Neighborhood Hits	70
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

SMC3_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.032603 (rank : 84)
Query Neighborhood Hits	162	Target Neighborhood Hits	1186	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.032647 (rank : 82)
Query Neighborhood Hits	162	Target Neighborhood Hits	1187	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SYCP1_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.029840 (rank : 96)
Query Neighborhood Hits	162	Target Neighborhood Hits	1313	Shared Neighborhood Hits	67
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TULP2_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.011904 (rank : 137)
Query Neighborhood Hits	162	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O00295	Gene names	TULP2
Domain Architecture
Description	Tubby-related protein 2 (Tubby-like protein 2).

CCD93_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.032113 (rank : 85)
Query Neighborhood Hits	162	Target Neighborhood Hits	600	Shared Neighborhood Hits	52
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

CE290_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.030628 (rank : 90)
Query Neighborhood Hits	162	Target Neighborhood Hits	1553	Shared Neighborhood Hits	72
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CP135_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.030456 (rank : 91)
Query Neighborhood Hits	162	Target Neighborhood Hits	1290	Shared Neighborhood Hits	73
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

JADE1_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.004370 (rank : 158)
Query Neighborhood Hits	162	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

MYO15_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.004741 (rank : 153)
Query Neighborhood Hits	162	Target Neighborhood Hits	467	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PDZD1_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.061859 (rank : 35)
Query Neighborhood Hits	162	Target Neighborhood Hits	191	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

POF1B_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.029355 (rank : 100)
Query Neighborhood Hits	162	Target Neighborhood Hits	494	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

RAD1_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.011444 (rank : 138)
Query Neighborhood Hits	162	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QWZ1, O70452, O88391, Q3TGU1, Q3UG66, Q9QWZ3	Gene names	Rad1, Rec1
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD1 (EC 3.1.11.2) (DNA repair exonuclease rad1 homolog) (Rad1-like DNA damage checkpoint protein) (mRAD1).

RPGR1_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.023108 (rank : 113)
Query Neighborhood Hits	162	Target Neighborhood Hits	713	Shared Neighborhood Hits	52
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SCEL_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.010924 (rank : 141)
Query Neighborhood Hits	162	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQG3, Q9CTT9	Gene names	Scel
Domain Architecture
Description	Sciellin.

TLN1_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.013940 (rank : 134)
Query Neighborhood Hits	162	Target Neighborhood Hits	213	Shared Neighborhood Hits	14
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

VIME_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.017269 (rank : 128)
Query Neighborhood Hits	162	Target Neighborhood Hits	706	Shared Neighborhood Hits	58
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

BMPR2_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.000213 (rank : 162)
Query Neighborhood Hits	162	Target Neighborhood Hits	738	Shared Neighborhood Hits	5
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

CCDC3_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.024159 (rank : 112)
Query Neighborhood Hits	162	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

CING_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.030633 (rank : 89)
Query Neighborhood Hits	162	Target Neighborhood Hits	1275	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

COQ6_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.008628 (rank : 147)
Query Neighborhood Hits	162	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1S0	Gene names	Coq6
Domain Architecture
Description	Ubiquinone biosynthesis monooxygenase COQ6 (EC 1.14.13.-).

COT1_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.004222 (rank : 159)
Query Neighborhood Hits	162	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

DCR1A_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.011266 (rank : 139)
Query Neighborhood Hits	162	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

GAS8_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.027313 (rank : 105)
Query Neighborhood Hits	162	Target Neighborhood Hits	819	Shared Neighborhood Hits	65
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

INT1_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.007493 (rank : 148)
Query Neighborhood Hits	162	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P4S8, Q80UQ7, Q91Z01, Q9CTF7	Gene names	Ints1
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

KIF17_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.011918 (rank : 136)
Query Neighborhood Hits	162	Target Neighborhood Hits	452	Shared Neighborhood Hits	31
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

KMHN1_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.028328 (rank : 104)
Query Neighborhood Hits	162	Target Neighborhood Hits	950	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KS6C1_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.001927 (rank : 160)
Query Neighborhood Hits	162	Target Neighborhood Hits	682	Shared Neighborhood Hits	3
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

LACTB_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.009509 (rank : 144)
Query Neighborhood Hits	162	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	P83111, P83096	Gene names	LACTB
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

MPP4_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.021357 (rank : 117)
Query Neighborhood Hits	162	Target Neighborhood Hits	205	Shared Neighborhood Hits	33
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

NFM_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.018557 (rank : 125)
Query Neighborhood Hits	162	Target Neighborhood Hits	1328	Shared Neighborhood Hits	66
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NFM_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.018335 (rank : 126)
Query Neighborhood Hits	162	Target Neighborhood Hits	1159	Shared Neighborhood Hits	65
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

NU214_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.015093 (rank : 132)
Query Neighborhood Hits	162	Target Neighborhood Hits	657	Shared Neighborhood Hits	25
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NUP88_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.019035 (rank : 123)
Query Neighborhood Hits	162	Target Neighborhood Hits	354	Shared Neighborhood Hits	35
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

PDZD3_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.068452 (rank : 34)
Query Neighborhood Hits	162	Target Neighborhood Hits	180	Shared Neighborhood Hits	38
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PININ_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.031343 (rank : 87)
Query Neighborhood Hits	162	Target Neighborhood Hits	753	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.030186 (rank : 94)
Query Neighborhood Hits	162	Target Neighborhood Hits	777	Shared Neighborhood Hits	54
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

POF1B_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.032639 (rank : 83)
Query Neighborhood Hits	162	Target Neighborhood Hits	530	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

PRRT3_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.006948 (rank : 150)
Query Neighborhood Hits	162	Target Neighborhood Hits	998	Shared Neighborhood Hits	21
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RARG1_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.004720 (rank : 154)
Query Neighborhood Hits	162	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG1_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.004713 (rank : 155)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.004694 (rank : 156)
Query Neighborhood Hits	162	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.004684 (rank : 157)
Query Neighborhood Hits	162	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RBP26_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.011184 (rank : 140)
Query Neighborhood Hits	162	Target Neighborhood Hits	146	Shared Neighborhood Hits	12
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

RIMB1_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.024680 (rank : 110)
Query Neighborhood Hits	162	Target Neighborhood Hits	1479	Shared Neighborhood Hits	70
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RMI1_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.008814 (rank : 145)
Query Neighborhood Hits	162	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9A7, Q5SQG8, Q5SQG9, Q6P1Q4, Q6PI89, Q7Z6L6	Gene names	RMI1, C9orf76
Domain Architecture	No domain graphic available
Description	Protein RMI1 homolog.

RPGF6_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.038465 (rank : 68)
Query Neighborhood Hits	162	Target Neighborhood Hits	266	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

SDPR_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.017713 (rank : 127)
Query Neighborhood Hits	162	Target Neighborhood Hits	485	Shared Neighborhood Hits	41
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SEN54_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.008725 (rank : 146)
Query Neighborhood Hits	162	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).

STP2_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.019304 (rank : 122)
Query Neighborhood Hits	162	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q05952, Q9NZB0	Gene names	TNP2
Domain Architecture
Description	Nuclear transition protein 2 (TP-2) (TP2).

VIME_MOUSE
θ value	8.99809 (rank : 162)	NC score	0.016708 (rank : 130)
Query Neighborhood Hits	162	Target Neighborhood Hits	716	Shared Neighborhood Hits	57
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

Hits sorted by NC score

SI1L1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	162	Target Neighborhood Hits	162	Shared Neighborhood Hits	162
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

SI1L1_MOUSE
NC score	0.994143 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	162	Target Neighborhood Hits	189	Shared Neighborhood Hits	113
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

SI1L2_MOUSE
NC score	0.978058 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	162	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L2_HUMAN
NC score	0.977285 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	162	Target Neighborhood Hits	131	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P2F8, Q5VXR7, Q5VXR8, Q641Q4, Q8NA38, Q96DZ3, Q9H9F6	Gene names	SIPA1L2, KIAA1389
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

SI1L3_HUMAN
NC score	0.954631 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	162	Target Neighborhood Hits	305	Shared Neighborhood Hits	45
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SIPA1_MOUSE
NC score	0.940008 (rank : 6)	θ value	9.45368e-175 (rank : 7)
Query Neighborhood Hits	162	Target Neighborhood Hits	158	Shared Neighborhood Hits	32
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

SIPA1_HUMAN
NC score	0.929786 (rank : 7)	θ value	6.75929e-181 (rank : 6)
Query Neighborhood Hits	162	Target Neighborhood Hits	250	Shared Neighborhood Hits	44
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

RGP2_HUMAN
NC score	0.883970 (rank : 8)	θ value	9.45883e-58 (rank : 8)
Query Neighborhood Hits	162	Target Neighborhood Hits	60	Shared Neighborhood Hits	12
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

GRIPE_HUMAN
NC score	0.458304 (rank : 9)	θ value	7.09661e-13 (rank : 9)
Query Neighborhood Hits	162	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GRIPE_MOUSE
NC score	0.445664 (rank : 10)	θ value	6.00763e-12 (rank : 10)
Query Neighborhood Hits	162	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

TSC2_HUMAN
NC score	0.432395 (rank : 11)	θ value	2.52405e-10 (rank : 11)
Query Neighborhood Hits	162	Target Neighborhood Hits	59	Shared Neighborhood Hits	14
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TSC2_MOUSE
NC score	0.410810 (rank : 12)	θ value	1.06045e-08 (rank : 12)
Query Neighborhood Hits	162	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q61037, P97723, P97724, P97725, P97727, Q61007, Q61008, Q9WUF6	Gene names	Tsc2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 homolog protein).

SHAN2_HUMAN
NC score	0.145236 (rank : 13)	θ value	0.0113563 (rank : 15)
Query Neighborhood Hits	162	Target Neighborhood Hits	346	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

APBA2_MOUSE
NC score	0.136462 (rank : 14)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	162	Target Neighborhood Hits	219	Shared Neighborhood Hits	39
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA2_HUMAN
NC score	0.136433 (rank : 15)	θ value	0.0330416 (rank : 18)
Query Neighborhood Hits	162	Target Neighborhood Hits	220	Shared Neighborhood Hits	39
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

APBA3_MOUSE
NC score	0.134827 (rank : 16)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	162	Target Neighborhood Hits	174	Shared Neighborhood Hits	40
SwissProt Accessions	O88888	Gene names	Apba3, Mint3
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

SHAN2_MOUSE
NC score	0.131771 (rank : 17)	θ value	0.0148317 (rank : 16)
Query Neighborhood Hits	162	Target Neighborhood Hits	446	Shared Neighborhood Hits	41
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

APBA1_HUMAN
NC score	0.121276 (rank : 18)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	162	Target Neighborhood Hits	325	Shared Neighborhood Hits	44
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

NHERF_HUMAN
NC score	0.120604 (rank : 19)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	162	Target Neighborhood Hits	190	Shared Neighborhood Hits	40
SwissProt Accessions	O14745, O43552, Q86WQ5	Gene names	SLC9A3R1, NHERF
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

APBA3_HUMAN
NC score	0.120032 (rank : 20)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	162	Target Neighborhood Hits	201	Shared Neighborhood Hits	37
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

NHERF_MOUSE
NC score	0.113470 (rank : 21)	θ value	0.125558 (rank : 29)
Query Neighborhood Hits	162	Target Neighborhood Hits	195	Shared Neighborhood Hits	40
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

USH1C_HUMAN
NC score	0.101843 (rank : 22)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	162	Target Neighborhood Hits	327	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y6N9, Q96B29, Q9UM04, Q9UM17, Q9UPC3	Gene names	USH1C, AIE75
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein) (Autoimmune enteropathy- related antigen AIE-75) (Antigen NY-CO-38/NY-CO-37) (PDZ-73 protein) (NY-REN-3 antigen).

USH1C_MOUSE
NC score	0.101542 (rank : 23)	θ value	0.279714 (rank : 35)
Query Neighborhood Hits	162	Target Neighborhood Hits	557	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ES64, Q91XD1, Q9CVG7, Q9ES65	Gene names	Ush1c
Domain Architecture
Description	Harmonin (Usher syndrome type-1C protein homolog) (PDZ domain- containing protein).

SHAN1_HUMAN
NC score	0.101111 (rank : 24)	θ value	0.00035302 (rank : 13)
Query Neighborhood Hits	162	Target Neighborhood Hits	1041	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PDZD3_MOUSE
NC score	0.100948 (rank : 25)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	162	Target Neighborhood Hits	171	Shared Neighborhood Hits	38
SwissProt Accessions	Q99MJ6, Q8BWE5	Gene names	Pdzd3, Pdzk2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).

NHRF2_HUMAN
NC score	0.090692 (rank : 26)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	162	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

PARD3_MOUSE
NC score	0.089154 (rank : 27)	θ value	0.0252991 (rank : 17)
Query Neighborhood Hits	162	Target Neighborhood Hits	290	Shared Neighborhood Hits	45
SwissProt Accessions	Q99NH2	Gene names	Pard3, Par3
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (Ephrin-interacting protein) (PHIP).

NHRF2_MOUSE
NC score	0.084870 (rank : 28)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	162	Target Neighborhood Hits	194	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JHL1, Q3TDR3, Q8BGL9, Q8BW05, Q9DCR6	Gene names	Slc9a3r2, Nherf2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2) (Octs2).

PARD3_HUMAN
NC score	0.082732 (rank : 29)	θ value	0.0431538 (rank : 21)
Query Neighborhood Hits	162	Target Neighborhood Hits	312	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

PDZD1_HUMAN
NC score	0.078498 (rank : 30)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	162	Target Neighborhood Hits	190	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T2W1, O60450, Q5T5P6, Q9BQ41	Gene names	PDZK1, CAP70, NHERF3, PDZD1
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

ARHGB_HUMAN
NC score	0.072528 (rank : 31)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	162	Target Neighborhood Hits	375	Shared Neighborhood Hits	45
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

WHRN_HUMAN
NC score	0.070884 (rank : 32)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	162	Target Neighborhood Hits	325	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P202, Q96MZ9, Q9H9F4, Q9UFZ3	Gene names	WHRN, DFNB31, KIAA1526
Domain Architecture	No domain graphic available
Description	Whirlin (Autosomal recessive deafness type 31 protein).

WHRN_MOUSE
NC score	0.068903 (rank : 33)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	162	Target Neighborhood Hits	412	Shared Neighborhood Hits	43
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

PDZD3_HUMAN
NC score	0.068452 (rank : 34)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	162	Target Neighborhood Hits	180	Shared Neighborhood Hits	38
SwissProt Accessions	Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3	Gene names	PDZD3, IKEPP, PDZK2
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).

PDZD1_MOUSE
NC score	0.061859 (rank : 35)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	162	Target Neighborhood Hits	191	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72	Gene names	Pdzk1, Cap70, Nherf3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).

VAPB_HUMAN
NC score	0.061214 (rank : 36)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	162	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	O95292, O95293, Q9P0H0	Gene names	VAPB
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B/C (VAMP- associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C).

PDZ11_HUMAN
NC score	0.060236 (rank : 37)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	162	Target Neighborhood Hits	160	Shared Neighborhood Hits	32
SwissProt Accessions	Q5EBL8, Q6UWE1, Q9P0Q1	Gene names	PDZD11, PDZK11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

CCDC6_HUMAN
NC score	0.058454 (rank : 38)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	162	Target Neighborhood Hits	723	Shared Neighborhood Hits	64
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

PDZ11_MOUSE
NC score	0.057977 (rank : 39)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	162	Target Neighborhood Hits	154	Shared Neighborhood Hits	27
SwissProt Accessions	Q9CZG9	Gene names	Pdzd11, Pdzk11
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 11.

RUFY2_MOUSE
NC score	0.056305 (rank : 40)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	162	Target Neighborhood Hits	820	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

HOME2_MOUSE
NC score	0.055499 (rank : 41)	θ value	0.00869519 (rank : 14)
Query Neighborhood Hits	162	Target Neighborhood Hits	882	Shared Neighborhood Hits	63
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

RUFY1_HUMAN
NC score	0.055218 (rank : 42)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	162	Target Neighborhood Hits	848	Shared Neighborhood Hits	65
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

MAGI1_HUMAN
NC score	0.054811 (rank : 43)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	162	Target Neighborhood Hits	388	Shared Neighborhood Hits	41
SwissProt Accessions	Q96QZ7, O00309, O43863, O75085, Q96QZ8, Q96QZ9	Gene names	MAGI1, BAIAP1, BAP1, TNRC19
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) (Atrophin-1-interacting protein 3) (AIP3) (WW domain-containing protein 3) (WWP3) (Trinucleotide repeat-containing gene 19 protein).

RUFY1_MOUSE
NC score	0.053452 (rank : 44)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	162	Target Neighborhood Hits	765	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

MPDZ_HUMAN
NC score	0.052545 (rank : 45)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	162	Target Neighborhood Hits	261	Shared Neighborhood Hits	39
SwissProt Accessions	O75970, O43798, Q5CZ80, Q5JTX3, Q5JTX6, Q5JTX7, Q5JUC3, Q5JUC4, Q5VZ62, Q8N790	Gene names	MPDZ, MUPP1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ- domain protein 1).

VAPB_MOUSE
NC score	0.052145 (rank : 46)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	162	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QY76	Gene names	Vapb
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein B (VAMP- associated protein B) (VAMP-associated protein 33b) (VAMP-B) (VAP-B).

MAGI1_MOUSE
NC score	0.052127 (rank : 47)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	162	Target Neighborhood Hits	403	Shared Neighborhood Hits	42
SwissProt Accessions	Q6RHR9, O54893, O54894, O54895	Gene names	Magi1, Baiap1, Bap1
Domain Architecture	No domain graphic available
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1).

MYOC_HUMAN
NC score	0.051604 (rank : 48)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	162	Target Neighborhood Hits	489	Shared Neighborhood Hits	53
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

MPDZ_MOUSE
NC score	0.050523 (rank : 49)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	162	Target Neighborhood Hits	298	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

LZTS1_MOUSE
NC score	0.047936 (rank : 50)	θ value	0.0563607 (rank : 22)
Query Neighborhood Hits	162	Target Neighborhood Hits	540	Shared Neighborhood Hits	55
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

LAP4_MOUSE
NC score	0.047022 (rank : 51)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	162	Target Neighborhood Hits	590	Shared Neighborhood Hits	47
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

RUFY2_HUMAN
NC score	0.046346 (rank : 52)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	162	Target Neighborhood Hits	1208	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

THAP6_HUMAN
NC score	0.046031 (rank : 53)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	162	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TBB0	Gene names	THAP6
Domain Architecture
Description	THAP domain-containing protein 6.

ZCH10_HUMAN
NC score	0.045559 (rank : 54)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	162	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TBK6, Q9NXR4	Gene names	ZCCHC10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

SNIP_MOUSE
NC score	0.044151 (rank : 55)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	162	Target Neighborhood Hits	319	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

GCC2_HUMAN
NC score	0.042918 (rank : 56)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	162	Target Neighborhood Hits	1558	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

PEPL_MOUSE
NC score	0.042466 (rank : 57)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	162	Target Neighborhood Hits	1105	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RBP24_HUMAN
NC score	0.042410 (rank : 58)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	162	Target Neighborhood Hits	1559	Shared Neighborhood Hits	77
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

EEA1_MOUSE
NC score	0.041946 (rank : 59)	θ value	0.0431538 (rank : 20)
Query Neighborhood Hits	162	Target Neighborhood Hits	1637	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

VAPA_HUMAN
NC score	0.041747 (rank : 60)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	162	Target Neighborhood Hits	23	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P0L0, O75453, Q5U0E7, Q9UBZ2	Gene names	VAPA, VAP33
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein A (VAMP- associated protein A) (VAMP-A) (VAP-A) (33 kDa Vamp-associated protein) (VAP-33).

VAPA_MOUSE
NC score	0.041486 (rank : 61)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	162	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WV55, Q3TJM1, Q9QY77	Gene names	Vapa, Vap33
Domain Architecture
Description	Vesicle-associated membrane protein-associated protein A (VAMP- associated protein A) (VAMP-A) (VAP-A) (33 kDa Vamp-associated protein) (VAP-33).

LAP4_HUMAN
NC score	0.040987 (rank : 62)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	162	Target Neighborhood Hits	608	Shared Neighborhood Hits	44
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

TPR_HUMAN
NC score	0.040445 (rank : 63)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	162	Target Neighborhood Hits	1921	Shared Neighborhood Hits	88
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

GOGA4_HUMAN
NC score	0.040248 (rank : 64)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	162	Target Neighborhood Hits	2034	Shared Neighborhood Hits	86
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CK5P2_HUMAN
NC score	0.039427 (rank : 65)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	162	Target Neighborhood Hits	1433	Shared Neighborhood Hits	75
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

TNIP3_HUMAN
NC score	0.039357 (rank : 66)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	162	Target Neighborhood Hits	511	Shared Neighborhood Hits	51
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

CYTSA_HUMAN
NC score	0.039018 (rank : 67)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	162	Target Neighborhood Hits	1138	Shared Neighborhood Hits	69
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

RPGF6_HUMAN
NC score	0.038465 (rank : 68)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	162	Target Neighborhood Hits	266	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TEU7, Q8NI21, Q8TEU6, Q96PC1	Gene names	RAPGEF6, PDZGEF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2).

FILA_HUMAN
NC score	0.038430 (rank : 69)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	162	Target Neighborhood Hits	685	Shared Neighborhood Hits	21
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

CK5P2_MOUSE
NC score	0.037667 (rank : 70)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	162	Target Neighborhood Hits	1151	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

EEA1_HUMAN
NC score	0.037353 (rank : 71)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	162	Target Neighborhood Hits	1796	Shared Neighborhood Hits	77
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

HMMR_HUMAN
NC score	0.036827 (rank : 72)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	162	Target Neighborhood Hits	1082	Shared Neighborhood Hits	71
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

CYTSA_MOUSE
NC score	0.036615 (rank : 73)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	162	Target Neighborhood Hits	1104	Shared Neighborhood Hits	65
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

MAP9_MOUSE
NC score	0.036294 (rank : 74)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	162	Target Neighborhood Hits	529	Shared Neighborhood Hits	44
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MACOI_MOUSE
NC score	0.036252 (rank : 75)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	162	Target Neighborhood Hits	620	Shared Neighborhood Hits	56
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

PTN13_HUMAN
NC score	0.035223 (rank : 76)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	162	Target Neighborhood Hits	471	Shared Neighborhood Hits	44
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

BPAEA_MOUSE
NC score	0.034019 (rank : 77)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	162	Target Neighborhood Hits	1480	Shared Neighborhood Hits	74
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HOOK3_MOUSE
NC score	0.033882 (rank : 78)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	162	Target Neighborhood Hits	1007	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

HOOK3_HUMAN
NC score	0.033706 (rank : 79)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	162	Target Neighborhood Hits	1070	Shared Neighborhood Hits	72
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

GOGB1_HUMAN
NC score	0.032994 (rank : 80)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	162	Target Neighborhood Hits	2297	Shared Neighborhood Hits	79
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SYCP1_MOUSE
NC score	0.032675 (rank : 81)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	162	Target Neighborhood Hits	1456	Shared Neighborhood Hits	70
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SMC3_MOUSE
NC score	0.032647 (rank : 82)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	162	Target Neighborhood Hits	1187	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

POF1B_MOUSE
NC score	0.032639 (rank : 83)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	162	Target Neighborhood Hits	530	Shared Neighborhood Hits	55
SwissProt Accessions	Q8K4L4, Q8C3A2	Gene names	Pof1b
Domain Architecture	No domain graphic available
Description	Protein POF1B.

SMC3_HUMAN
NC score	0.032603 (rank : 84)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	162	Target Neighborhood Hits	1186	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

CCD93_HUMAN
NC score	0.032113 (rank : 85)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	162	Target Neighborhood Hits	600	Shared Neighborhood Hits	52
SwissProt Accessions	Q567U6, Q4LE78, Q53TJ2, Q8TBX5, Q9H6R5, Q9NV15	Gene names	CCDC93
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 93.

DYNA_MOUSE
NC score	0.031368 (rank : 86)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	162	Target Neighborhood Hits	1084	Shared Neighborhood Hits	66
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

PININ_HUMAN
NC score	0.031343 (rank : 87)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	162	Target Neighborhood Hits	753	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

DYNA_HUMAN
NC score	0.030696 (rank : 88)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	162	Target Neighborhood Hits	1194	Shared Neighborhood Hits	68
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

CING_HUMAN
NC score	0.030633 (rank : 89)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	162	Target Neighborhood Hits	1275	Shared Neighborhood Hits	73
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CE290_HUMAN
NC score	0.030628 (rank : 90)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	162	Target Neighborhood Hits	1553	Shared Neighborhood Hits	72
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CP135_HUMAN
NC score	0.030456 (rank : 91)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	162	Target Neighborhood Hits	1290	Shared Neighborhood Hits	73
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

BPAEA_HUMAN
NC score	0.030362 (rank : 92)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	162	Target Neighborhood Hits	1369	Shared Neighborhood Hits	70
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PPRB_HUMAN
NC score	0.030276 (rank : 93)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	162	Target Neighborhood Hits	311	Shared Neighborhood Hits	11
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PININ_MOUSE
NC score	0.030186 (rank : 94)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	162	Target Neighborhood Hits	777	Shared Neighborhood Hits	54
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SBDS_HUMAN
NC score	0.029925 (rank : 95)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	162	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y3A5, Q96FX0, Q9NV53	Gene names	SBDS
Domain Architecture
Description	Shwachman-Bodian-Diamond syndrome protein.

SYCP1_HUMAN
NC score	0.029840 (rank : 96)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	162	Target Neighborhood Hits	1313	Shared Neighborhood Hits	67
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CI039_HUMAN
NC score	0.029686 (rank : 97)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	162	Target Neighborhood Hits	1171	Shared Neighborhood Hits	69
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

MD1L1_MOUSE
NC score	0.029584 (rank : 98)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	162	Target Neighborhood Hits	1001	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

RAD50_MOUSE
NC score	0.029562 (rank : 99)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	162	Target Neighborhood Hits	1366	Shared Neighborhood Hits	69
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

POF1B_HUMAN
NC score	0.029355 (rank : 100)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	162	Target Neighborhood Hits	494	Shared Neighborhood Hits	52
SwissProt Accessions	Q8WVV4, Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744	Gene names	POF1B
Domain Architecture	No domain graphic available
Description	Protein POF1B (Premature ovarian failure protein 1B).

CENPE_HUMAN
NC score	0.029302 (rank : 101)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	162	Target Neighborhood Hits	2060	Shared Neighborhood Hits	78
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RAD50_HUMAN
NC score	0.028989 (rank : 102)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	162	Target Neighborhood Hits	1317	Shared Neighborhood Hits	70
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

LIPA1_HUMAN
NC score	0.028531 (rank : 103)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	162	Target Neighborhood Hits	1294	Shared Neighborhood Hits	77
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

KMHN1_HUMAN
NC score	0.028328 (rank : 104)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	162	Target Neighborhood Hits	950	Shared Neighborhood Hits	62
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

GAS8_HUMAN
NC score	0.027313 (rank : 105)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	162	Target Neighborhood Hits	819	Shared Neighborhood Hits	65
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

SBDS_MOUSE
NC score	0.027233 (rank : 106)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	162	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P70122, Q3TG78, Q9CR18	Gene names	Sbds
Domain Architecture
Description	Shwachman-Bodian-Diamond syndrome protein homolog (Protein 22A3).

HAP1_HUMAN
NC score	0.026681 (rank : 107)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	162	Target Neighborhood Hits	606	Shared Neighborhood Hits	56
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

RAI14_MOUSE
NC score	0.026344 (rank : 108)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	162	Target Neighborhood Hits	1505	Shared Neighborhood Hits	76
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CTGE6_HUMAN
NC score	0.024853 (rank : 109)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	162	Target Neighborhood Hits	650	Shared Neighborhood Hits	55
SwissProt Accessions	Q86UF2	Gene names	CTAGE6
Domain Architecture	No domain graphic available
Description	Protein cTAGE-6 (cTAGE family member 6).

RIMB1_HUMAN
NC score	0.024680 (rank : 110)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	162	Target Neighborhood Hits	1479	Shared Neighborhood Hits	70
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ANR26_HUMAN
NC score	0.024271 (rank : 111)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	162	Target Neighborhood Hits	1614	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CCDC3_MOUSE
NC score	0.024159 (rank : 112)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	162	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D6Y1	Gene names	Ccdc3
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 3 precursor.

RPGR1_MOUSE
NC score	0.023108 (rank : 113)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	162	Target Neighborhood Hits	713	Shared Neighborhood Hits	52
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

NSDHL_MOUSE
NC score	0.023050 (rank : 114)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	162	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1J0, O55109	Gene names	Nsdhl
Domain Architecture
Description	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (EC 1.1.1.170).

NCOR2_MOUSE
NC score	0.021830 (rank : 115)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	162	Target Neighborhood Hits	790	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

MAP1B_HUMAN
NC score	0.021827 (rank : 116)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	162	Target Neighborhood Hits	903	Shared Neighborhood Hits	47
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MPP4_HUMAN
NC score	0.021357 (rank : 117)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	162	Target Neighborhood Hits	205	Shared Neighborhood Hits	33
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

MYH7_HUMAN
NC score	0.021060 (rank : 118)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	162	Target Neighborhood Hits	1559	Shared Neighborhood Hits	74
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PKHG1_HUMAN
NC score	0.020221 (rank : 119)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	162	Target Neighborhood Hits	174	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

OXR1_MOUSE
NC score	0.020094 (rank : 120)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	162	Target Neighborhood Hits	516	Shared Neighborhood Hits	28
SwissProt Accessions	Q4KMM3, Q5FWW1, Q99L06, Q99MK1, Q99MP4	Gene names	Oxr1, C7
Domain Architecture	No domain graphic available
Description	Oxidation resistance protein 1 (Protein C7).

KCNB2_HUMAN
NC score	0.019915 (rank : 121)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	162	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

STP2_HUMAN
NC score	0.019304 (rank : 122)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	162	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q05952, Q9NZB0	Gene names	TNP2
Domain Architecture
Description	Nuclear transition protein 2 (TP-2) (TP2).

NUP88_HUMAN
NC score	0.019035 (rank : 123)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	162	Target Neighborhood Hits	354	Shared Neighborhood Hits	35
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

DOCK4_MOUSE
NC score	0.018770 (rank : 124)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	162	Target Neighborhood Hits	210	Shared Neighborhood Hits	10
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

NFM_HUMAN
NC score	0.018557 (rank : 125)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	162	Target Neighborhood Hits	1328	Shared Neighborhood Hits	66
SwissProt Accessions	P07197	Gene names	NEF3, NEFM, NFM
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3).

NFM_MOUSE
NC score	0.018335 (rank : 126)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	162	Target Neighborhood Hits	1159	Shared Neighborhood Hits	65
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

SDPR_MOUSE
NC score	0.017713 (rank : 127)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	162	Target Neighborhood Hits	485	Shared Neighborhood Hits	41
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

VIME_HUMAN
NC score	0.017269 (rank : 128)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	162	Target Neighborhood Hits	706	Shared Neighborhood Hits	58
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

TBCD1_HUMAN
NC score	0.016925 (rank : 129)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	162	Target Neighborhood Hits	276	Shared Neighborhood Hits	27
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

VIME_MOUSE
NC score	0.016708 (rank : 130)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	162	Target Neighborhood Hits	716	Shared Neighborhood Hits	57
SwissProt Accessions	P20152, O08704, Q8CCH1	Gene names	Vim
Domain Architecture
Description	Vimentin.

DOCK4_HUMAN
NC score	0.015550 (rank : 131)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	162	Target Neighborhood Hits	237	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

NU214_HUMAN
NC score	0.015093 (rank : 132)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	162	Target Neighborhood Hits	657	Shared Neighborhood Hits	25
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

CNOT4_MOUSE
NC score	0.014407 (rank : 133)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	162	Target Neighborhood Hits	277	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

TLN1_MOUSE
NC score	0.013940 (rank : 134)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	162	Target Neighborhood Hits	213	Shared Neighborhood Hits	14
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

OTOF_HUMAN
NC score	0.012035 (rank : 135)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	162	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

KIF17_MOUSE
NC score	0.011918 (rank : 136)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	162	Target Neighborhood Hits	452	Shared Neighborhood Hits	31
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

TULP2_HUMAN
NC score	0.011904 (rank : 137)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	162	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	O00295	Gene names	TULP2
Domain Architecture
Description	Tubby-related protein 2 (Tubby-like protein 2).

RAD1_MOUSE
NC score	0.011444 (rank : 138)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	162	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QWZ1, O70452, O88391, Q3TGU1, Q3UG66, Q9QWZ3	Gene names	Rad1, Rec1
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD1 (EC 3.1.11.2) (DNA repair exonuclease rad1 homolog) (Rad1-like DNA damage checkpoint protein) (mRAD1).

DCR1A_MOUSE
NC score	0.011266 (rank : 139)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	162	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JIC3, Q571H5, Q6GQR6	Gene names	Dclre1a, Kiaa0086, Snm1, Snm1a
Domain Architecture	No domain graphic available
Description	DNA cross-link repair 1A protein.

RBP26_HUMAN
NC score	0.011184 (rank : 140)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	162	Target Neighborhood Hits	146	Shared Neighborhood Hits	12
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

SCEL_MOUSE
NC score	0.010924 (rank : 141)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	162	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EQG3, Q9CTT9	Gene names	Scel
Domain Architecture
Description	Sciellin.

SMCA2_HUMAN
NC score	0.010868 (rank : 142)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	162	Target Neighborhood Hits	503	Shared Neighborhood Hits	20
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

IASPP_HUMAN
NC score	0.009828 (rank : 143)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	162	Target Neighborhood Hits	688	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LACTB_HUMAN
NC score	0.009509 (rank : 144)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	162	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	P83111, P83096	Gene names	LACTB
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

RMI1_HUMAN
NC score	0.008814 (rank : 145)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	162	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H9A7, Q5SQG8, Q5SQG9, Q6P1Q4, Q6PI89, Q7Z6L6	Gene names	RMI1, C9orf76
Domain Architecture	No domain graphic available
Description	Protein RMI1 homolog.

SEN54_HUMAN
NC score	0.008725 (rank : 146)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	162	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z6J9, Q86WV3, Q86XE4, Q8N9H2	Gene names	TSEN54, SEN54
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen54 (tRNA-intron endonuclease Sen54) (HsSen54).

COQ6_MOUSE
NC score	0.008628 (rank : 147)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	162	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R1S0	Gene names	Coq6
Domain Architecture
Description	Ubiquinone biosynthesis monooxygenase COQ6 (EC 1.14.13.-).

INT1_MOUSE
NC score	0.007493 (rank : 148)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	162	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P4S8, Q80UQ7, Q91Z01, Q9CTF7	Gene names	Ints1
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

ST5_HUMAN
NC score	0.007305 (rank : 149)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	162	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	P78524, P78523, Q16492, Q7KYY2, Q7KZ12, Q8NE12, Q9BQQ6	Gene names	ST5, DENND2B, HTS1
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (HeLa tumor suppression 1) (DENN domain-containing protein 2B).

PRRT3_HUMAN
NC score	0.006948 (rank : 150)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	162	Target Neighborhood Hits	998	Shared Neighborhood Hits	21
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

GATA5_MOUSE
NC score	0.006937 (rank : 151)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	162	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P97489	Gene names	Gata5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

COT1_MOUSE
NC score	0.004868 (rank : 152)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	162	Target Neighborhood Hits	160	Shared Neighborhood Hits	8
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

MYO15_MOUSE
NC score	0.004741 (rank : 153)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	162	Target Neighborhood Hits	467	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RARG1_HUMAN
NC score	0.004720 (rank : 154)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	162	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG1_MOUSE
NC score	0.004713 (rank : 155)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_HUMAN
NC score	0.004694 (rank : 156)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	162	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
NC score	0.004684 (rank : 157)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	162	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

JADE1_HUMAN
NC score	0.004370 (rank : 158)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	162	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

COT1_HUMAN
NC score	0.004222 (rank : 159)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	162	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

KS6C1_HUMAN
NC score	0.001927 (rank : 160)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	162	Target Neighborhood Hits	682	Shared Neighborhood Hits	3
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

NOTC2_HUMAN
NC score	0.001191 (rank : 161)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	162	Target Neighborhood Hits	1113	Shared Neighborhood Hits	8
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

BMPR2_MOUSE
NC score	0.000213 (rank : 162)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	162	Target Neighborhood Hits	738	Shared Neighborhood Hits	5
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).