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Network neighborhood for query Sequence : LACTB_HUMAN

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LACTB_HUMAN
SwissProt Accessions	P83111, P83096	Gene names	LACTB
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LACTB_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	62	Target Neighborhood Hits	62	Shared Neighborhood Hits	62
SwissProt Accessions	P83111, P83096	Gene names	LACTB
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

LACTB_MOUSE
θ value	0 (rank : 2)	NC score	0.977604 (rank : 2)
Query Neighborhood Hits	62	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EP89	Gene names	Lactb, Lact1
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

MAP1A_HUMAN
θ value	0.0193708 (rank : 3)	NC score	0.066752 (rank : 6)
Query Neighborhood Hits	62	Target Neighborhood Hits	1626	Shared Neighborhood Hits	41
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NANO3_HUMAN
θ value	0.0736092 (rank : 4)	NC score	0.075521 (rank : 4)
Query Neighborhood Hits	62	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P60323	Gene names	NANOS3, NOS3
Domain Architecture	No domain graphic available
Description	Nanos homolog 3.

STAC3_MOUSE
θ value	0.0961366 (rank : 5)	NC score	0.042717 (rank : 7)
Query Neighborhood Hits	62	Target Neighborhood Hits	232	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

SEC62_MOUSE
θ value	0.163984 (rank : 6)	NC score	0.092318 (rank : 3)
Query Neighborhood Hits	62	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BU14, Q6NX81	Gene names	Tloc1, Sec62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1).

RAD50_HUMAN
θ value	0.365318 (rank : 7)	NC score	0.034180 (rank : 16)
Query Neighborhood Hits	62	Target Neighborhood Hits	1317	Shared Neighborhood Hits	38
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

NFM_MOUSE
θ value	0.47712 (rank : 8)	NC score	0.022498 (rank : 38)
Query Neighborhood Hits	62	Target Neighborhood Hits	1159	Shared Neighborhood Hits	31
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

CAF1A_MOUSE
θ value	0.62314 (rank : 9)	NC score	0.040219 (rank : 10)
Query Neighborhood Hits	62	Target Neighborhood Hits	736	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CN145_MOUSE
θ value	0.62314 (rank : 10)	NC score	0.032346 (rank : 19)
Query Neighborhood Hits	62	Target Neighborhood Hits	916	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

TOP1_MOUSE
θ value	1.06291 (rank : 11)	NC score	0.036368 (rank : 12)
Query Neighborhood Hits	62	Target Neighborhood Hits	213	Shared Neighborhood Hits	8
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

NFL_HUMAN
θ value	1.38821 (rank : 12)	NC score	0.018407 (rank : 45)
Query Neighborhood Hits	62	Target Neighborhood Hits	666	Shared Neighborhood Hits	18
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

INCE_HUMAN
θ value	1.81305 (rank : 13)	NC score	0.030768 (rank : 22)
Query Neighborhood Hits	62	Target Neighborhood Hits	978	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

RYR1_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.024862 (rank : 33)
Query Neighborhood Hits	62	Target Neighborhood Hits	303	Shared Neighborhood Hits	5
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

CCD46_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.029083 (rank : 26)
Query Neighborhood Hits	62	Target Neighborhood Hits	1430	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CTGE4_HUMAN
θ value	2.36792 (rank : 16)	NC score	0.024457 (rank : 34)
Query Neighborhood Hits	62	Target Neighborhood Hits	393	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

MOES_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.023093 (rank : 37)
Query Neighborhood Hits	62	Target Neighborhood Hits	892	Shared Neighborhood Hits	25
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PDIA3_MOUSE
θ value	2.36792 (rank : 18)	NC score	0.019233 (rank : 43)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

PHLB1_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.034233 (rank : 15)
Query Neighborhood Hits	62	Target Neighborhood Hits	1038	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PININ_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.040850 (rank : 9)
Query Neighborhood Hits	62	Target Neighborhood Hits	753	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

SEC62_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.071131 (rank : 5)
Query Neighborhood Hits	62	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

IF2P_HUMAN
θ value	3.0926 (rank : 22)	NC score	0.031593 (rank : 20)
Query Neighborhood Hits	62	Target Neighborhood Hits	889	Shared Neighborhood Hits	19
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

PININ_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.041065 (rank : 8)
Query Neighborhood Hits	62	Target Neighborhood Hits	777	Shared Neighborhood Hits	29
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

THOC2_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.034618 (rank : 14)
Query Neighborhood Hits	62	Target Neighborhood Hits	337	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

ARI4A_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.032561 (rank : 17)
Query Neighborhood Hits	62	Target Neighborhood Hits	434	Shared Neighborhood Hits	14
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

EEA1_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.028226 (rank : 28)
Query Neighborhood Hits	62	Target Neighborhood Hits	1637	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FYB_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.027008 (rank : 29)
Query Neighborhood Hits	62	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

NEK1_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.003732 (rank : 61)
Query Neighborhood Hits	62	Target Neighborhood Hits	1129	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

PHLB1_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.030582 (rank : 24)
Query Neighborhood Hits	62	Target Neighborhood Hits	678	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RB6I2_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.025161 (rank : 32)
Query Neighborhood Hits	62	Target Neighborhood Hits	1584	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RBBP6_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.035431 (rank : 13)
Query Neighborhood Hits	62	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RPGR1_MOUSE
θ value	4.03905 (rank : 32)	NC score	0.029792 (rank : 25)
Query Neighborhood Hits	62	Target Neighborhood Hits	713	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RXINP_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.030890 (rank : 21)
Query Neighborhood Hits	62	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

TAF3_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.032362 (rank : 18)
Query Neighborhood Hits	62	Target Neighborhood Hits	568	Shared Neighborhood Hits	20
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CD2L1_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.004710 (rank : 60)
Query Neighborhood Hits	62	Target Neighborhood Hits	1467	Shared Neighborhood Hits	19
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

CIR_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.026370 (rank : 30)
Query Neighborhood Hits	62	Target Neighborhood Hits	249	Shared Neighborhood Hits	8
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

DSRAD_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.016390 (rank : 48)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

MAP1B_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.038544 (rank : 11)
Query Neighborhood Hits	62	Target Neighborhood Hits	903	Shared Neighborhood Hits	24
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MOES_MOUSE
θ value	5.27518 (rank : 39)	NC score	0.021663 (rank : 40)
Query Neighborhood Hits	62	Target Neighborhood Hits	923	Shared Neighborhood Hits	22
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MYO6_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.010720 (rank : 56)
Query Neighborhood Hits	62	Target Neighborhood Hits	586	Shared Neighborhood Hits	18
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

SETD8_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.021078 (rank : 41)
Query Neighborhood Hits	62	Target Neighborhood Hits	131	Shared Neighborhood Hits	9
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

TLK1_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.003583 (rank : 62)
Query Neighborhood Hits	62	Target Neighborhood Hits	967	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).

BAZ1B_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.025256 (rank : 31)
Query Neighborhood Hits	62	Target Neighborhood Hits	701	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

DACT1_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.018687 (rank : 44)
Query Neighborhood Hits	62	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

HS90A_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.017742 (rank : 47)
Query Neighborhood Hits	62	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

REST_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.024107 (rank : 36)
Query Neighborhood Hits	62	Target Neighborhood Hits	1605	Shared Neighborhood Hits	39
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SMC2_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.024378 (rank : 35)
Query Neighborhood Hits	62	Target Neighborhood Hits	1131	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SPAT7_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.020919 (rank : 42)
Query Neighborhood Hits	62	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P0W8, Q8WX30, Q96HF3, Q9H0X0, Q9P0W7	Gene names	SPATA7, HSD3
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 7 (Spermatogenesis-associated protein HSD3) (HSD-3.1).

TAF3_MOUSE
θ value	6.88961 (rank : 49)	NC score	0.030732 (rank : 23)
Query Neighborhood Hits	62	Target Neighborhood Hits	463	Shared Neighborhood Hits	17
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

ABCF1_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.013264 (rank : 54)
Query Neighborhood Hits	62	Target Neighborhood Hits	343	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

BAZ2A_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.012552 (rank : 55)
Query Neighborhood Hits	62	Target Neighborhood Hits	780	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BPA1_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.014185 (rank : 53)
Query Neighborhood Hits	62	Target Neighborhood Hits	1477	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CBX1_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.014849 (rank : 50)
Query Neighborhood Hits	62	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.014849 (rank : 51)
Query Neighborhood Hits	62	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CHD5_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.007571 (rank : 59)
Query Neighborhood Hits	62	Target Neighborhood Hits	349	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

HS90A_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.018182 (rank : 46)
Query Neighborhood Hits	62	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

MAP9_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.028233 (rank : 27)
Query Neighborhood Hits	62	Target Neighborhood Hits	518	Shared Neighborhood Hits	17
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

NACAM_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.010272 (rank : 57)
Query Neighborhood Hits	62	Target Neighborhood Hits	1866	Shared Neighborhood Hits	14
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

REST_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.022183 (rank : 39)
Query Neighborhood Hits	62	Target Neighborhood Hits	1506	Shared Neighborhood Hits	36
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SI1L1_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.009509 (rank : 58)
Query Neighborhood Hits	62	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

WDR75_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.014387 (rank : 52)
Query Neighborhood Hits	62	Target Neighborhood Hits	193	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWA0, Q96J10, Q9H8U8, Q9H9U5, Q9H9V8, Q9UIX2	Gene names	WDR75
Domain Architecture	No domain graphic available
Description	WD repeat protein 75.

XTP3B_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.015194 (rank : 49)
Query Neighborhood Hits	62	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VEH8, Q3UZF3, Q8BVN6	Gene names
Domain Architecture	No domain graphic available
Description	XTP3-transactivated gene B protein homolog precursor.

Hits sorted by NC score

LACTB_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	62	Target Neighborhood Hits	62	Shared Neighborhood Hits	62
SwissProt Accessions	P83111, P83096	Gene names	LACTB
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

LACTB_MOUSE
NC score	0.977604 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	62	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EP89	Gene names	Lactb, Lact1
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

SEC62_MOUSE
NC score	0.092318 (rank : 3)	θ value	0.163984 (rank : 6)
Query Neighborhood Hits	62	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BU14, Q6NX81	Gene names	Tloc1, Sec62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1).

NANO3_HUMAN
NC score	0.075521 (rank : 4)	θ value	0.0736092 (rank : 4)
Query Neighborhood Hits	62	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P60323	Gene names	NANOS3, NOS3
Domain Architecture	No domain graphic available
Description	Nanos homolog 3.

SEC62_HUMAN
NC score	0.071131 (rank : 5)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	62	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q99442, O00682, O00729	Gene names	TLOC1, SEC62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1).

MAP1A_HUMAN
NC score	0.066752 (rank : 6)	θ value	0.0193708 (rank : 3)
Query Neighborhood Hits	62	Target Neighborhood Hits	1626	Shared Neighborhood Hits	41
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

STAC3_MOUSE
NC score	0.042717 (rank : 7)	θ value	0.0961366 (rank : 5)
Query Neighborhood Hits	62	Target Neighborhood Hits	232	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

PININ_MOUSE
NC score	0.041065 (rank : 8)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	62	Target Neighborhood Hits	777	Shared Neighborhood Hits	29
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PININ_HUMAN
NC score	0.040850 (rank : 9)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	62	Target Neighborhood Hits	753	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CAF1A_MOUSE
NC score	0.040219 (rank : 10)	θ value	0.62314 (rank : 9)
Query Neighborhood Hits	62	Target Neighborhood Hits	736	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

MAP1B_HUMAN
NC score	0.038544 (rank : 11)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	62	Target Neighborhood Hits	903	Shared Neighborhood Hits	24
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

TOP1_MOUSE
NC score	0.036368 (rank : 12)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	62	Target Neighborhood Hits	213	Shared Neighborhood Hits	8
SwissProt Accessions	Q04750	Gene names	Top1, Top-1
Domain Architecture
Description	DNA topoisomerase 1 (EC 5.99.1.2) (DNA topoisomerase I).

RBBP6_HUMAN
NC score	0.035431 (rank : 13)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	62	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

THOC2_HUMAN
NC score	0.034618 (rank : 14)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	62	Target Neighborhood Hits	337	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

PHLB1_HUMAN
NC score	0.034233 (rank : 15)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	62	Target Neighborhood Hits	1038	Shared Neighborhood Hits	26
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RAD50_HUMAN
NC score	0.034180 (rank : 16)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	62	Target Neighborhood Hits	1317	Shared Neighborhood Hits	38
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

ARI4A_HUMAN
NC score	0.032561 (rank : 17)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	62	Target Neighborhood Hits	434	Shared Neighborhood Hits	14
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

TAF3_HUMAN
NC score	0.032362 (rank : 18)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	62	Target Neighborhood Hits	568	Shared Neighborhood Hits	20
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CN145_MOUSE
NC score	0.032346 (rank : 19)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	62	Target Neighborhood Hits	916	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

IF2P_HUMAN
NC score	0.031593 (rank : 20)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	62	Target Neighborhood Hits	889	Shared Neighborhood Hits	19
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

RXINP_HUMAN
NC score	0.030890 (rank : 21)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	62	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

INCE_HUMAN
NC score	0.030768 (rank : 22)	θ value	1.81305 (rank : 13)
Query Neighborhood Hits	62	Target Neighborhood Hits	978	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

TAF3_MOUSE
NC score	0.030732 (rank : 23)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	62	Target Neighborhood Hits	463	Shared Neighborhood Hits	17
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

PHLB1_MOUSE
NC score	0.030582 (rank : 24)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	62	Target Neighborhood Hits	678	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RPGR1_MOUSE
NC score	0.029792 (rank : 25)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	62	Target Neighborhood Hits	713	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CCD46_HUMAN
NC score	0.029083 (rank : 26)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	62	Target Neighborhood Hits	1430	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

MAP9_HUMAN
NC score	0.028233 (rank : 27)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	62	Target Neighborhood Hits	518	Shared Neighborhood Hits	17
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

EEA1_MOUSE
NC score	0.028226 (rank : 28)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	62	Target Neighborhood Hits	1637	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FYB_MOUSE
NC score	0.027008 (rank : 29)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	62	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

CIR_HUMAN
NC score	0.026370 (rank : 30)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	62	Target Neighborhood Hits	249	Shared Neighborhood Hits	8
SwissProt Accessions	Q86X95, O95367, Q12804, Q4G1B9, Q6PJI4, Q8IWI2	Gene names	CIR
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor (Recepin).

BAZ1B_HUMAN
NC score	0.025256 (rank : 31)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	62	Target Neighborhood Hits	701	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

RB6I2_HUMAN
NC score	0.025161 (rank : 32)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	62	Target Neighborhood Hits	1584	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RYR1_HUMAN
NC score	0.024862 (rank : 33)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	62	Target Neighborhood Hits	303	Shared Neighborhood Hits	5
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

CTGE4_HUMAN
NC score	0.024457 (rank : 34)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	62	Target Neighborhood Hits	393	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

SMC2_MOUSE
NC score	0.024378 (rank : 35)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	62	Target Neighborhood Hits	1131	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

REST_HUMAN
NC score	0.024107 (rank : 36)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	62	Target Neighborhood Hits	1605	Shared Neighborhood Hits	39
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

MOES_HUMAN
NC score	0.023093 (rank : 37)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	62	Target Neighborhood Hits	892	Shared Neighborhood Hits	25
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

NFM_MOUSE
NC score	0.022498 (rank : 38)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	62	Target Neighborhood Hits	1159	Shared Neighborhood Hits	31
SwissProt Accessions	P08553, Q61961	Gene names	Nef3, Nefm, Nfm
Domain Architecture
Description	Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M).

REST_MOUSE
NC score	0.022183 (rank : 39)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	62	Target Neighborhood Hits	1506	Shared Neighborhood Hits	36
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

MOES_MOUSE
NC score	0.021663 (rank : 40)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	62	Target Neighborhood Hits	923	Shared Neighborhood Hits	22
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

SETD8_MOUSE
NC score	0.021078 (rank : 41)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	62	Target Neighborhood Hits	131	Shared Neighborhood Hits	9
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SPAT7_HUMAN
NC score	0.020919 (rank : 42)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	62	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q9P0W8, Q8WX30, Q96HF3, Q9H0X0, Q9P0W7	Gene names	SPATA7, HSD3
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 7 (Spermatogenesis-associated protein HSD3) (HSD-3.1).

PDIA3_MOUSE
NC score	0.019233 (rank : 43)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

DACT1_HUMAN
NC score	0.018687 (rank : 44)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	62	Target Neighborhood Hits	228	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

NFL_HUMAN
NC score	0.018407 (rank : 45)	θ value	1.38821 (rank : 12)
Query Neighborhood Hits	62	Target Neighborhood Hits	666	Shared Neighborhood Hits	18
SwissProt Accessions	P07196, Q16154, Q8IU72	Gene names	NEFL, NF68, NFL
Domain Architecture
Description	Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L).

HS90A_HUMAN
NC score	0.018182 (rank : 46)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	62	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

HS90A_MOUSE
NC score	0.017742 (rank : 47)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	62	Target Neighborhood Hits	155	Shared Neighborhood Hits	6
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

DSRAD_HUMAN
NC score	0.016390 (rank : 48)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	62	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

XTP3B_MOUSE
NC score	0.015194 (rank : 49)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	62	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VEH8, Q3UZF3, Q8BVN6	Gene names
Domain Architecture	No domain graphic available
Description	XTP3-transactivated gene B protein homolog precursor.

CBX1_HUMAN
NC score	0.014849 (rank : 50)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	62	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.014849 (rank : 51)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	62	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

WDR75_HUMAN
NC score	0.014387 (rank : 52)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	62	Target Neighborhood Hits	193	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWA0, Q96J10, Q9H8U8, Q9H9U5, Q9H9V8, Q9UIX2	Gene names	WDR75
Domain Architecture	No domain graphic available
Description	WD repeat protein 75.

BPA1_MOUSE
NC score	0.014185 (rank : 53)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	62	Target Neighborhood Hits	1477	Shared Neighborhood Hits	35
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ABCF1_HUMAN
NC score	0.013264 (rank : 54)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	62	Target Neighborhood Hits	343	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

BAZ2A_HUMAN
NC score	0.012552 (rank : 55)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	62	Target Neighborhood Hits	780	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

MYO6_MOUSE
NC score	0.010720 (rank : 56)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	62	Target Neighborhood Hits	586	Shared Neighborhood Hits	18
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

NACAM_MOUSE
NC score	0.010272 (rank : 57)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	62	Target Neighborhood Hits	1866	Shared Neighborhood Hits	14
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SI1L1_HUMAN
NC score	0.009509 (rank : 58)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	62	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	O43166, O95321, Q9UDU4, Q9UNU4	Gene names	SIPA1L1, E6TP1, KIAA0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1 (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6- targeted protein 1).

CHD5_HUMAN
NC score	0.007571 (rank : 59)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	62	Target Neighborhood Hits	349	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CD2L1_HUMAN
NC score	0.004710 (rank : 60)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	62	Target Neighborhood Hits	1467	Shared Neighborhood Hits	19
SwissProt Accessions	P21127, O95265, Q12817, Q12818, Q12819, Q12820, Q12822, Q8N530, Q9NZS5, Q9UBJ0, Q9UBQ1, Q9UBR0, Q9UNY2, Q9UP57, Q9UP58, Q9UP59	Gene names	CDC2L1, PITSLREA, PK58
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1) (CLK-1) (CDK11) (p58 CLK-1).

NEK1_HUMAN
NC score	0.003732 (rank : 61)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	62	Target Neighborhood Hits	1129	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PY6, Q9Y594	Gene names	NEK1, KIAA1901
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1) (NY-REN-55 antigen).

TLK1_HUMAN
NC score	0.003583 (rank : 62)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	62	Target Neighborhood Hits	967	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UKI8, Q14150, Q8N591, Q9NYH2, Q9Y4F6	Gene names	TLK1, KIAA0137
Domain Architecture
Description	Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (Tousled- like kinase 1) (PKU-beta).